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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for MAFF_MAFG

Z-value: 2.03

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Transcription factors associated with MAFF_MAFG

Gene Symbol Gene ID Gene Info
MAFF
ENSG00000185022.7 MAFF
MAFG
ENSG00000197063.6 MAFG

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
MAFFchr22_38610191_386103427240.537857-0.636.9e-02Click!
MAFFchr22_38598543_385986951840.911091-0.608.8e-02Click!
MAFFchr22_38610915_3861106614480.282218-0.599.7e-02Click!
MAFFchr22_38610451_3861070910380.390786-0.432.5e-01Click!
MAFFchr22_38598076_385984612650.864198-0.402.8e-01Click!
MAFGchr17_79884123_798852838810.222449-0.511.7e-01Click!
MAFGchr17_79882093_798823778270.257316-0.481.9e-01Click!
MAFGchr17_79881842_798819935090.428578-0.402.9e-01Click!
MAFGchr17_79882996_7988314716630.115033-0.166.9e-01Click!
MAFGchr17_79882380_7988253110470.1948810.117.7e-01Click!

Activity of the MAFF_MAFG motif across conditions

Conditions sorted by the z-value of the MAFF_MAFG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr4_17060566_17060738 0.92 LDB2
 LIM domain binding 2
 160220
 0.04
chr1_172112919_172113144 0.84 ENSG00000208024
 .
 753
 0.46
chr21_17567832_17567983 0.81 ENSG00000201025
 .
 89182
 0.1
chr13_22190759_22190945 0.75 MICU2
 mitochondrial calcium uptake 2
 12499
 0.22
chr19_44139197_44139620 0.74 CADM4
 cell adhesion molecule 4
 4583
 0.1
chr4_4784046_4784388 0.74 MSX1
 msh homeobox 1
 77176
 0.11
chr18_56244442_56244608 0.72 RP11-126O1.2
20223
 0.14
chr5_71403752_71403990 0.72 MAP1B
 microtubule-associated protein 1B
 558
 0.84
chr18_12278485_12278651 0.72 CIDEA
 cell death-inducing DFFA-like effector a
 24250
 0.15
chr5_52132959_52133110 0.70 CTD-2288O8.1
49174
 0.13
chr11_12309017_12309498 0.69 MICALCL
 MICAL C-terminal like
 810
 0.62
chr4_119754084_119754235 0.68 SEC24D
 SEC24 family member D
 3134
 0.34
chr18_52551233_52551384 0.67 RAB27B
 RAB27B, member RAS oncogene family
 280
 0.92
chr6_24443792_24443943 0.66 MRS2
 MRS2 magnesium transporter
 40447
 0.12
chr10_17274225_17274484 0.65 VIM
 vimentin
 1746
 0.26
chr3_89163237_89163857 0.65 EPHA3
 EPH receptor A3
 6721
 0.35
chr12_106530238_106530817 0.65 NUAK1
 NUAK family, SNF1-like kinase, 1
 3284
 0.3
chr7_42646131_42646414 0.64 C7orf25
 chromosome 7 open reading frame 25
 305237
 0.01
chr10_116761272_116761462 0.64 ENSG00000252611
 .
 32040
 0.2
chr2_27301899_27302732 0.63 EMILIN1
 elastin microfibril interfacer 1
 880
 0.32
chr9_21688149_21688723 0.63 ENSG00000244230
 .
 10877
 0.24
chr2_203883174_203883392 0.62 NBEAL1
 neurobeachin-like 1
 3681
 0.28
chr2_38300397_38300595 0.62 CYP1B1-AS1
 CYP1B1 antisense RNA 1
 2295
 0.25
chr17_15209957_15210211 0.61 ENSG00000200437
 .
 4578
 0.19
chr7_90355616_90355767 0.61 CDK14
 cyclin-dependent kinase 14
 16515
 0.28
chr6_112554565_112554822 0.60 RP11-506B6.6
2601
 0.27
chr7_5464589_5465209 0.60 TNRC18
 trinucleotide repeat containing 18
 146
 0.94
chr8_50822371_50822736 0.59 SNTG1
 syntrophin, gamma 1
 204
 0.97
chr5_141699076_141699254 0.58 SPRY4
 sprouty homolog 4 (Drosophila)
 4582
 0.25
chr9_22102802_22102953 0.58 CDKN2B-AS1
 CDKN2B antisense RNA 1
 10800
 0.25
chr3_110792322_110792622 0.57 PVRL3
 poliovirus receptor-related 3
 579
 0.76
chr5_146783513_146783669 0.57 CTB-108O6.2
2268
 0.31
chr2_105475160_105475311 0.56 POU3F3
 POU class 3 homeobox 3
 3266
 0.17
chr5_158438402_158438767 0.56 CTD-2363C16.2
25770
 0.2
chr18_2856996_2857255 0.55 EMILIN2
 elastin microfibril interfacer 2
 10097
 0.16
chr18_34273309_34273594 0.54 FHOD3
 formin homology 2 domain containing 3
 25069
 0.22
chr3_147115262_147115580 0.54 ZIC1
 Zic family member 1
 3739
 0.21
chr5_57754273_57754664 0.53 PLK2
 polo-like kinase 2
 1619
 0.44
chr3_64172371_64172810 0.53 PRICKLE2-AS3
 PRICKLE2 antisense RNA 3
 630
 0.74
chr1_212810509_212810859 0.53 RP11-338C15.5
10571
 0.14
chr15_70994402_70994652 0.52 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 93
 0.98
chr21_45139141_45140358 0.52 PDXK
 pyridoxal (pyridoxine, vitamin B6) kinase
 756
 0.66
chr13_21654404_21654812 0.51 LATS2
 large tumor suppressor kinase 2
 18922
 0.14
chr1_185903548_185903809 0.51 HMCN1
 hemicentin 1
 199995
 0.03
chr6_28175291_28175856 0.51 ZSCAN9
 zinc finger and SCAN domain containing 9
 17091
 0.12
chr6_169828167_169828442 0.51 THBS2
 thrombospondin 2
 174165
 0.03
chr8_103663875_103664026 0.51 KLF10
 Kruppel-like factor 10
 2653
 0.33
chr1_60031328_60031726 0.51 FGGY
 FGGY carbohydrate kinase domain containing
 11937
 0.3
chr14_72052991_72053258 0.50 SIPA1L1
 signal-induced proliferation-associated 1 like 1
 126
 0.98
chr12_57522507_57523183 0.50 STAT6
 signal transducer and activator of transcription 6, interleukin-4 induced
 38
 0.64
chr11_121800053_121800533 0.50 ENSG00000252556
 .
 74770
 0.11
chr3_112359324_112359570 0.50 CCDC80
 coiled-coil domain containing 80
 669
 0.77
chr2_134325508_134325697 0.50 NCKAP5
 NCK-associated protein 5
 429
 0.88
chr4_134068181_134068851 0.50 PCDH10
 protocadherin 10
 1954
 0.52
chr15_23810880_23811333 0.49 MKRN3
 makorin ring finger protein 3
 186
 0.93
chr7_18794470_18794725 0.49 ENSG00000222164
 .
 53305
 0.17
chr3_45052751_45053653 0.49 CLEC3B
 C-type lectin domain family 3, member B
 14473
 0.15
chr6_56556586_56556809 0.49 DST
 dystonin
 48903
 0.18
chr6_2111373_2111600 0.49 GMDS
 GDP-mannose 4,6-dehydratase
 64739
 0.15
chr3_30975573_30975751 0.49 GADL1
 glutamate decarboxylase-like 1
 39405
 0.22
chr7_97952929_97953353 0.48 RP11-307C18.1
976
 0.55
chr10_114886062_114886413 0.48 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
 17442
 0.28
chr8_75667241_75667392 0.48 PI15
 peptidase inhibitor 15
 69456
 0.11
chr7_137026886_137027037 0.48 PTN
 pleiotrophin
 1559
 0.52
chr17_79884123_79885283 0.48 MAFG
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
 881
 0.22
chr8_119628036_119628187 0.47 SAMD12
 sterile alpha motif domain containing 12
 6073
 0.34
chrX_69674453_69675874 0.47 DLG3
 discs, large homolog 3 (Drosophila)
 217
 0.75
chrX_152760469_152760831 0.47 BGN
 biglycan
 199
 0.63
chr5_108441798_108441949 0.47 ENSG00000206593
 .
 91232
 0.1
chr11_112755544_112755695 0.47 RP11-629G13.1
76402
 0.1
chr3_184503907_184504131 0.46 VPS8
 vacuolar protein sorting 8 homolog (S. cerevisiae)
 25912
 0.22
chr4_40765446_40765597 0.46 NSUN7
 NOP2/Sun domain family, member 7
 13579
 0.2
chr6_11196915_11197406 0.46 RP3-510L9.1
23475
 0.18
chr3_16218692_16218887 0.46 GALNT15
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
 2573
 0.36
chr5_173959976_173960345 0.46 MSX2
 msh homeobox 2
 191376
 0.03
chr14_24836692_24836908 0.46 NFATC4
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
 92
 0.93
chr2_202774749_202774932 0.46 ENSG00000212184
 .
 17322
 0.18
chr19_30205840_30206749 0.46 C19orf12
 chromosome 19 open reading frame 12
 133
 0.97
chr4_126237829_126238914 0.46 FAT4
 FAT atypical cadherin 4
 817
 0.75
chr2_177024685_177024984 0.45 HOXD3
 homeobox D3
 785
 0.4
chr4_138354057_138354215 0.45 PCDH18
 protocadherin 18
 99429
 0.09
chr5_42944152_42944647 0.45 SEPP1
 selenoprotein P, plasma, 1
 56905
 0.11
chr8_15398730_15398881 0.45 TUSC3
 tumor suppressor candidate 3
 1013
 0.64
chr5_81064717_81065068 0.45 SSBP2
 single-stranded DNA binding protein 2
 17820
 0.28
chr16_73235490_73235677 0.45 C16orf47
 chromosome 16 open reading frame 47
 57237
 0.16
chr12_52400775_52401965 0.45 GRASP
 GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
 646
 0.62
chr16_73053803_73054015 0.44 AC002044.4
5534
 0.23
chr2_47141058_47141265 0.44 MCFD2
 multiple coagulation factor deficiency 2
 52
 0.96
chr3_154798433_154798647 0.44 MME
 membrane metallo-endopeptidase
 213
 0.97
chr5_169230334_169230676 0.44 CTB-37A13.1
24136
 0.22
chr2_69922345_69922564 0.44 ENSG00000238708
 .
 27963
 0.17
chr4_114304583_114304734 0.44 ANK2
 ankyrin 2, neuronal
 10143
 0.22
chr4_148947373_148947715 0.44 RP11-76G10.1
120078
 0.06
chr2_38301385_38301690 0.44 CYP1B1-AS1
 CYP1B1 antisense RNA 1
 1254
 0.37
chr5_106403324_106403615 0.44 ENSG00000252337
 .
 521103
 0.0
chr8_32505564_32505715 0.43 NRG1
 neuregulin 1
 282
 0.95
chr9_100181817_100181968 0.43 TDRD7
 tudor domain containing 7
 7516
 0.23
chr14_56711281_56711464 0.43 PELI2
 pellino E3 ubiquitin protein ligase family member 2
 125545
 0.06
chr11_78767245_78767406 0.43 ENSG00000266550
 .
 82471
 0.11
chr8_117586987_117587193 0.43 EIF3H
 eukaryotic translation initiation factor 3, subunit H
 180933
 0.03
chr7_29605545_29606286 0.43 PRR15
 proline rich 15
 849
 0.6
chr19_45655667_45657201 0.43 NKPD1
 NTPase, KAP family P-loop domain containing 1
 594
 0.58
chr7_43739481_43739640 0.43 COA1
 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
 29491
 0.18
chr4_119948488_119948716 0.43 SYNPO2
 synaptopodin 2
 3976
 0.33
chr20_56706361_56706780 0.42 C20orf85
 chromosome 20 open reading frame 85
 19390
 0.21
chr7_73915534_73915685 0.42 GTF2IRD1
 GTF2I repeat domain containing 1
 4713
 0.23
chr1_170633420_170634117 0.42 PRRX1
 paired related homeobox 1
 690
 0.8
chr18_57332365_57332516 0.42 CCBE1
 collagen and calcium binding EGF domains 1
 954
 0.57
chr10_114718428_114718838 0.42 RP11-57H14.2
6999
 0.23
chr10_95751804_95751990 0.42 PLCE1
 phospholipase C, epsilon 1
 1849
 0.4
chr4_15471443_15471718 0.42 CC2D2A
 coiled-coil and C2 domain containing 2A
 26
 0.98
chr15_48378818_48378969 0.42 SLC24A5
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
 34276
 0.16
chr12_101191303_101191454 0.42 ANO4
 anoctamin 4
 2642
 0.36
chr1_85065027_85065219 0.42 CTBS
 chitobiase, di-N-acetyl-
 24976
 0.17
chr1_61668583_61669016 0.42 RP4-802A10.1
78394
 0.11
chr13_96293825_96294023 0.42 DZIP1
 DAZ interacting zinc finger protein 1
 1593
 0.43
chr10_17276728_17276924 0.41 RP11-124N14.3
6
 0.97
chr2_238317343_238317737 0.41 COL6A3
 collagen, type VI, alpha 3
 5251
 0.23
chr17_13424489_13424747 0.41 ENSG00000266115
 .
 20973
 0.19
chr1_8354218_8354369 0.41 ENSG00000251977
 .
 1970
 0.28
chr9_12776208_12776436 0.41 LURAP1L
 leucine rich adaptor protein 1-like
 1302
 0.47
chr6_163776165_163776497 0.41 QKI
 QKI, KH domain containing, RNA binding
 59344
 0.15
chr2_28565345_28565858 0.40 AC093690.1
32275
 0.15
chr15_71148071_71148222 0.40 LARP6
 La ribonucleoprotein domain family, member 6
 1648
 0.3
chr6_46376004_46376155 0.40 RCAN2
 regulator of calcineurin 2
 48634
 0.16
chr18_24125857_24126142 0.40 KCTD1
 potassium channel tetramerization domain containing 1
 964
 0.65
chr18_57214984_57215158 0.40 RP11-760L24.1
15870
 0.23
chr8_71005594_71005799 0.40 ENSG00000212473
 .
 15429
 0.2
chr13_111863178_111863377 0.40 ARHGEF7
 Rho guanine nucleotide exchange factor (GEF) 7
 5641
 0.26
chr14_73248118_73248269 0.40 ENSG00000206751
 .
 71846
 0.11
chr11_28695349_28695500 0.40 ENSG00000222385
 .
 412358
 0.01
chr1_39329527_39329678 0.40 RP5-864K19.4
3847
 0.16
chr17_67137803_67138011 0.40 ABCA6
 ATP-binding cassette, sub-family A (ABC1), member 6
 108
 0.97
chr1_231297648_231298418 0.40 TRIM67
 tripartite motif containing 67
 175
 0.95
chr12_118424590_118424864 0.40 KSR2
 kinase suppressor of ras 2
 17939
 0.19
chr1_109262925_109263076 0.39 FNDC7
 fibronectin type III domain containing 7
 2033
 0.27
chr10_5491314_5491465 0.39 NET1
 neuroepithelial cell transforming 1
 2815
 0.24
chr19_57182553_57183430 0.39 ZNF835
 zinc finger protein 835
 137
 0.95
chrX_51640322_51640473 0.39 MAGED1
 melanoma antigen family D, 1
 3662
 0.29
chr12_107525847_107526024 0.39 CRY1
 cryptochrome 1 (photolyase-like)
 38328
 0.17
chr15_90205872_90206267 0.39 PLIN1
 perilipin 1
 4802
 0.14
chr16_27256849_27257000 0.39 NSMCE1
 non-SMC element 1 homolog (S. cerevisiae)
 12525
 0.16
chr3_129407054_129407730 0.39 TMCC1
 transmembrane and coiled-coil domain family 1
 183
 0.96
chr17_65427494_65427948 0.39 ENSG00000201547
 .
 22724
 0.12
chrX_53310382_53310778 0.39 IQSEC2
 IQ motif and Sec7 domain 2
 216
 0.94
chr2_239765903_239766187 0.39 TWIST2
 twist family bHLH transcription factor 2
 9372
 0.26
chr6_146868018_146868556 0.39 RAB32
 RAB32, member RAS oncogene family
 3458
 0.33
chr6_25266628_25266779 0.39 RP3-522P13.3
5064
 0.18
chr8_129234068_129234219 0.39 ENSG00000201782
 .
 1393
 0.56
chr1_49413886_49414037 0.39 AGBL4
 ATP/GTP binding protein-like 4
 97425
 0.08
chr9_79292400_79292551 0.39 ENSG00000265488
 .
 11473
 0.22
chr5_80251688_80251866 0.38 CTC-459I6.1
2978
 0.3
chr12_20000310_20000490 0.38 ENSG00000200885
 .
 123031
 0.06
chr6_97545575_97545734 0.38 KLHL32
 kelch-like family member 32
 33150
 0.23
chr2_98765349_98765752 0.38 VWA3B
 von Willebrand factor A domain containing 3B
 61851
 0.13
chr2_39355170_39355412 0.38 ENSG00000202309
 .
 777
 0.61
chr1_156872582_156872733 0.38 PEAR1
 platelet endothelial aggregation receptor 1
 9134
 0.13
chr20_32803614_32804224 0.38 ASIP
 agouti signaling protein
 21544
 0.17
chr12_78796897_78797048 0.38 NAV3
 neuron navigator 3
 204116
 0.03
chr11_118475977_118476197 0.38 PHLDB1
 pleckstrin homology-like domain, family B, member 1
 1068
 0.37
chr3_71275125_71275276 0.38 FOXP1
 forkhead box P1
 19116
 0.26
chr5_123150123_123150346 0.38 CSNK1G3
 casein kinase 1, gamma 3
 226115
 0.02
chr8_13371594_13371816 0.38 DLC1
 deleted in liver cancer 1
 569
 0.79
chr4_170189368_170189538 0.38 SH3RF1
 SH3 domain containing ring finger 1
 1655
 0.5
chr3_134369918_134370289 0.38 KY
 kyphoscoliosis peptidase
 239
 0.94
chr2_187713432_187714439 0.38 ZSWIM2
 zinc finger, SWIM-type containing 2
 38
 0.99
chr1_214470760_214470948 0.38 SMYD2
 SET and MYND domain containing 2
 16278
 0.26
chr3_134183800_134183951 0.38 CEP63
 centrosomal protein 63kDa
 20710
 0.16
chr1_163137606_163137757 0.37 RP11-267N12.1
6216
 0.24
chr15_63664284_63664568 0.37 CA12
 carbonic anhydrase XII
 9608
 0.26
chr4_81160065_81160216 0.37 FGF5
 fibroblast growth factor 5
 27613
 0.18
chr3_27368413_27368573 0.37 NEK10
 NIMA-related kinase 10
 35445
 0.15
chr12_115251305_115251544 0.37 ENSG00000252459
 .
 75915
 0.12
chr13_74487387_74487624 0.37 KLF12
 Kruppel-like factor 12
 81681
 0.12
chr21_33836527_33836765 0.37 EVA1C
 eva-1 homolog C (C. elegans)
 36004
 0.13
chr1_94219763_94219914 0.37 RP11-488P3.1
21162
 0.21
chr13_52158653_52159782 0.37 WDFY2
 WD repeat and FYVE domain containing 2
 573
 0.6
chr2_121498772_121498953 0.37 GLI2
 GLI family zinc finger 2
 5039
 0.32
chr8_55294582_55295235 0.37 ENSG00000244107
 .
 38120
 0.17
chr21_39654900_39655051 0.37 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
 10546
 0.28
chr15_49718551_49718707 0.37 FGF7
 fibroblast growth factor 7
 3172
 0.3
chr10_114787759_114788133 0.37 RP11-57H14.2
76312
 0.1
chr16_30856305_30856895 0.37 MIR4519
 microRNA 4519
 29943
 0.07
chr15_99215068_99215236 0.37 IGF1R
 insulin-like growth factor 1 receptor
 22879
 0.2
chr16_65154468_65154619 0.36 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 1290
 0.65
chr3_178684614_178685138 0.36 ZMAT3
 zinc finger, matrin-type 3
 104478
 0.06
chr21_36936389_36936667 0.36 ENSG00000211590
 .
 156485
 0.04
chr18_8707466_8707765 0.36 RP11-674N23.1
4
 0.73
chr7_115868519_115868670 0.36 TES
 testis derived transcript (3 LIM domains)
 5736
 0.23
chr6_56573707_56573932 0.36 DST
 dystonin
 66025
 0.13
chr4_119948824_119949052 0.36 SYNPO2
 synaptopodin 2
 4312
 0.32
chr8_89310599_89310750 0.36 RP11-586K2.1
28391
 0.2
chr7_80547175_80548098 0.36 SEMA3C
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
 863
 0.76
chr7_90758039_90758190 0.36 FZD1
 frizzled family receptor 1
 135669
 0.05
chr3_114343374_114343541 0.36 ZBTB20
 zinc finger and BTB domain containing 20
 335
 0.94
chr15_39875260_39875463 0.36 THBS1
 thrombospondin 1
 2067
 0.32
chr5_37836619_37837236 0.36 GDNF
 glial cell derived neurotrophic factor
 998
 0.64
chr13_98826071_98826283 0.36 RNF113B
 ring finger protein 113B
 3342
 0.2
chr17_13266074_13266343 0.36 ENSG00000266115
 .
 137437
 0.05
chr1_243962680_243962831 0.36 AKT3-IT1
 AKT3 intronic transcript 1 (non-protein coding)
 5053
 0.27

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of MAFF_MAFG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 0.6 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.6 GO:0010665 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.7 GO:0060841 venous blood vessel development(GO:0060841)
0.1 0.4 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.3 GO:0021508 floor plate formation(GO:0021508)
0.1 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.3 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.1 0.3 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.3 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1 0.6 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.3 GO:0048293 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.1 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.8 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.2 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.1 0.2 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.2 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.1 0.5 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.3 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.3 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.4 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.1 GO:0003157 endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.1 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.2 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.1 GO:0021825 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.7 GO:0035329 hippo signaling(GO:0035329)
0.1 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.3 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.2 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.2 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.3 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.1 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.0 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.2 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.2 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.3 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0060413 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.2 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.0 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.3 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.1 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.0 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0003211 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0031579 membrane raft organization(GO:0031579)
0.0 0.2 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0032347 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.2 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.2 GO:0001660 fever generation(GO:0001660)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.0 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.2 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.0 0.3 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.2 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.0 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0048566 embryonic digestive tract development(GO:0048566)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0014002 astrocyte development(GO:0014002)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.0 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.1 GO:0035930 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.2 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.8 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.1 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.0 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.0 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.2 GO:0010596 negative regulation of endothelial cell migration(GO:0010596)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0032770 positive regulation of monooxygenase activity(GO:0032770)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.0 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.3 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.0 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.0 GO:0007343 egg activation(GO:0007343)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.1 GO:0007530 sex determination(GO:0007530)
0.0 0.0 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0070391 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0 0.1 GO:0070198 protein localization to chromosome, telomeric region(GO:0070198)
0.0 0.0 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.0 GO:0010224 response to UV-B(GO:0010224)
0.0 0.1 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.0 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.2 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.2 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.1 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.0 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.0 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.0 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.0 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.0 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.0 GO:0090311 regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.4 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.1 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0051583 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0009129 pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0 0.0 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.0 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.0 GO:0061082 myeloid leukocyte cytokine production(GO:0061082)
0.0 0.0 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.4 GO:0005916 fascia adherens(GO:0005916)
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.9 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.9 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0043656 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.6 GO:0030018 Z disc(GO:0030018)
0.0 0.0 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.0 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.0 GO:0071437 invadopodium(GO:0071437)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.2 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.6 GO:0042383 sarcolemma(GO:0042383)
0.0 0.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.8 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.7 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.9 GO:0034705 potassium channel complex(GO:0034705)
0.0 0.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.6 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.3 GO:0002060 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.2 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.1 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.3 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.1 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.0 GO:0034618 arginine binding(GO:0034618)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.0 GO:0031782 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0048038 quinone binding(GO:0048038)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.0 GO:0046980 tapasin binding(GO:0046980)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID IGF1 PATHWAY IGF1 pathway
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.1 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.0 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG