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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for MBD2

Z-value: 0.57

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Transcription factors associated with MBD2

Gene Symbol	Gene ID	Gene Info
MBD2 Ensembl NCBI GeneCards UniProt	ENSG00000134046.7	MBD2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
MBD2	chr18_51751599_51751750	516	0.785603	-0.85	3.8e-03	Click!
MBD2	chr18_51766045_51766196	14962	0.186217	0.38	3.1e-01	Click!
MBD2	chr18_51749801_51749975	1099	0.380751	-0.32	4.0e-01	Click!
MBD2	chr18_51750360_51750511	552	0.724562	-0.13	7.3e-01	Click!
MBD2	chr18_51751166_51751526	188	0.944061	-0.13	7.3e-01	Click!

Activity of the MBD2 motif across conditions

Conditions sorted by the z-value of the MBD2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_80189068_80189889	0.26	SLC16A3	solute carrier family 16 (monocarboxylate transporter), member 3	630	0.57
chr6_166721057_166722024	0.25	PRR18	proline rich 18	331	0.9
chr4_74809740_74810515	0.22	PF4	platelet factor 4	37714	0.11
chr3_36985452_36986747	0.20	TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	449	0.83
chr12_3308931_3310293	0.19	TSPAN9	tetraspanin 9	729	0.75
chr3_142681892_142682427	0.19	PAQR9	progestin and adipoQ receptor family member IX	19	0.84
chr20_43729394_43729952	0.19	KCNS1	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1	77	0.96
chr21_44496501_44497065	0.18	CBS	cystathionine-beta-synthase	270	0.91
chrX_48748285_48749195	0.17	TIMM17B	translocase of inner mitochondrial membrane 17 homolog B (yeast)	6290	0.1
chr2_27485345_27486489	0.17	SLC30A3	solute carrier family 30 (zinc transporter), member 3	178	0.89
chr3_196594834_196595961	0.17	SENP5	SUMO1/sentrin specific peptidase 5	581	0.72
chr10_94449633_94450257	0.16	HHEX	hematopoietically expressed homeobox	898	0.6
chr3_192126971_192127690	0.15	FGF12	fibroblast growth factor 12	492	0.87
chr18_70210992_70211675	0.15	CBLN2	cerebellin 2 precursor	441	0.91
chr7_128171824_128173030	0.15	RP11-274B21.1		1279	0.43
chr5_149864820_149865733	0.14	NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	105	0.97
chr10_98592747_98593792	0.14	LCOR	ligand dependent nuclear receptor corepressor	532	0.78
chr3_39194337_39194962	0.14	CSRNP1	cysteine-serine-rich nuclear protein 1	417	0.84
chr15_56035451_56035609	0.14	PRTG	protogenin	242	0.94
chr17_78234751_78235551	0.14	RNF213	ring finger protein 213	482	0.76
chr4_71570546_71572213	0.13	RUFY3	RUN and FYVE domain containing 3	861	0.36
chr5_74907170_74908023	0.13	ANKDD1B	ankyrin repeat and death domain containing 1B	312	0.9
chr2_185463143_185463634	0.13	ZNF804A	zinc finger protein 804A	295	0.95
chr13_29068702_29069490	0.13	FLT1	fms-related tyrosine kinase 1	136	0.98
chr17_73584494_73585142	0.13	MYO15B	myosin XVB pseudogene	2040	0.21
chrX_39964334_39965624	0.13	BCOR	BCL6 corepressor	8323	0.32
chr1_180881914_180882730	0.12	KIAA1614	KIAA1614	3	0.98
chr3_195384928_195385957	0.12	SDHAP2	succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2	475	0.81
chr15_99192776_99194432	0.12	IGF1R	insulin-like growth factor 1 receptor	1331	0.47
chr17_20491916_20492779	0.12	CDRT15L2	CMT1A duplicated region transcript 15-like 2	9310	0.21
chr16_691284_692401	0.12	FAM195A	family with sequence similarity 195, member A	29	0.92
chr2_160653969_160654659	0.11	CD302	CD302 molecule	439	0.87
chr22_20003723_20004755	0.11	ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	92	0.75
chr21_37529152_37530122	0.11	DOPEY2	dopey family member 2	557	0.57
chr14_100706520_100706671	0.11	YY1	YY1 transcription factor	499	0.64
chr22_29601932_29602692	0.11	EMID1	EMI domain containing 1	400	0.8
chr8_144512945_144513817	0.11	MAFA	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A	805	0.48
chr5_134825154_134825603	0.11	TIFAB	TRAF-interacting protein with forkhead-associated domain, family member B	37289	0.11
chr18_77558508_77558774	0.10	KCNG2	potassium voltage-gated channel, subfamily G, member 2	65027	0.12
chr18_11149170_11149978	0.10	PIEZO2	piezo-type mechanosensitive ion channel component 2	987	0.72
chr7_2394785_2395825	0.10	EIF3B	eukaryotic translation initiation factor 3, subunit B	788	0.53
chr10_102278895_102279852	0.10	SEC31B	SEC31 homolog B (S. cerevisiae)	218	0.92
chr11_62455448_62455813	0.10	LRRN4CL	LRRN4 C-terminal like	1741	0.12
chr11_119019412_119020504	0.10	ABCG4	ATP-binding cassette, sub-family G (WHITE), member 4	5	0.94
chr3_141379125_141379497	0.10	RNF7	ring finger protein 7	77735	0.09
chr13_21634768_21635319	0.10	LATS2	large tumor suppressor kinase 2	614	0.69
chr19_10982465_10983821	0.10	CARM1	coactivator-associated arginine methyltransferase 1	764	0.53
chr3_197463352_197463883	0.10	KIAA0226	KIAA0226	27	0.88
chr2_8818889_8820001	0.10	AC011747.7		259	0.7
chrX_36975622_36976198	0.10	FAM47C	family with sequence similarity 47, member C	50522	0.19
chrX_53349448_53350467	0.10	IQSEC2	IQ motif and Sec7 domain 2	565	0.73
chr15_69113585_69114214	0.10	ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	665	0.75
chr11_63535609_63536120	0.09	ENSG00000264519	.	29679	0.13
chr20_3073179_3074190	0.09	ENSG00000263905	.	1177	0.34
chr1_159750747_159751482	0.09	DUSP23	dual specificity phosphatase 23	321	0.85
chr18_74843262_74844680	0.09	MBP	myelin basic protein	331	0.94
chrX_119384747_119385998	0.09	ZBTB33	zinc finger and BTB domain containing 33	762	0.69
chr12_6937518_6938631	0.09	LEPREL2	leprecan-like 2	502	0.55
chr2_103235205_103235939	0.09	SLC9A2	solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2	594	0.82
chr12_14720104_14720509	0.09	RP11-695J4.2		378	0.73
chr16_66638822_66640143	0.09	CMTM3	CKLF-like MARVEL transmembrane domain containing 3	58	0.95
chr5_42944152_42944647	0.09	SEPP1	selenoprotein P, plasma, 1	56905	0.11
chr5_76506770_76507546	0.09	PDE8B	phosphodiesterase 8B	407	0.88
chr1_17446030_17446253	0.09	PADI2	peptidyl arginine deiminase, type II	193	0.94
chr16_70221940_70222878	0.09	CLEC18C	C-type lectin domain family 18, member C	14349	0.1
chr4_128543868_128544388	0.09	INTU	inturned planar cell polarity protein	298	0.94
chr1_45008521_45008672	0.09	ENSG00000263381	.	2569	0.31
chr7_18125753_18126403	0.08	HDAC9	histone deacetylase 9	494	0.84
chr1_36923329_36923682	0.08	MRPS15	mitochondrial ribosomal protein S15	6533	0.14
chr6_85472920_85473300	0.08	TBX18	T-box 18	37	0.99
chr20_49347136_49348386	0.08	PARD6B	par-6 family cell polarity regulator beta	320	0.89
chr1_103573929_103574109	0.08	COL11A1	collagen, type XI, alpha 1	16	0.99
chr20_32273512_32274295	0.08	E2F1	E2F transcription factor 1	307	0.81
chr14_101034010_101035263	0.08	BEGAIN	brain-enriched guanylate kinase-associated	192	0.93
chr8_142138821_142140144	0.08	RP11-809O17.1		578	0.46
chr5_133861629_133862874	0.08	JADE2	jade family PHD finger 2	76	0.97
chr9_77501796_77502826	0.08	TRPM6	transient receptor potential cation channel, subfamily M, member 6	48	0.97
chr13_114822852_114823008	0.08	RASA3	RAS p21 protein activator 3	20508	0.23
chr18_499765_500605	0.08	COLEC12	collectin sub-family member 12	537	0.79
chr20_31351193_31351609	0.08	DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	953	0.56
chr11_68780491_68780695	0.08	MRGPRF	MAS-related GPR, member F	121	0.88
chr20_39657787_39658990	0.08	TOP1	topoisomerase (DNA) I	930	0.61
chr13_27131903_27132772	0.08	WASF3	WAS protein family, member 3	450	0.89
chr10_27547544_27548544	0.08	ARMC4P1	armadillo repeat containing 4 pseudogene 1	3842	0.17
chr3_195635375_195636127	0.08	TNK2	tyrosine kinase, non-receptor, 2	204	0.83
chr10_6186918_6187892	0.08	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	508	0.72
chr8_67624599_67625774	0.08	SGK3	serum/glucocorticoid regulated kinase family, member 3	533	0.76
chr17_79268296_79269061	0.08	SLC38A10	solute carrier family 38, member 10	389	0.8
chr7_92218956_92219793	0.08	FAM133B	family with sequence similarity 133, member B	10	0.98
chr13_99227754_99228977	0.08	STK24	serine/threonine kinase 24	752	0.54
chr1_53685385_53686250	0.08	C1orf123	chromosome 1 open reading frame 123	472	0.43
chr17_38498589_38499681	0.08	CTD-2267D19.2		253	0.69
chr16_85793355_85793506	0.08	C16orf74	chromosome 16 open reading frame 74	8695	0.11
chr4_682374_683342	0.07	MFSD7	major facilitator superfamily domain containing 7	74	0.94
chr18_12376105_12377115	0.07	AFG3L2	AFG3-like AAA ATPase 2	391	0.83
chr5_1110808_1112337	0.07	SLC12A7	solute carrier family 12 (potassium/chloride transporter), member 7	578	0.75
chr10_27148230_27149879	0.07	ABI1	abl-interactor 1	738	0.67
chr17_2296252_2297077	0.07	MNT	MAX network transcriptional repressor	7734	0.11
chr6_7051751_7052548	0.07	ENSG00000251762	.	11370	0.24
chr7_127671114_127671650	0.07	LRRC4	leucine rich repeat containing 4	259	0.94
chr8_136470073_136470726	0.07	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	69	0.96
chr1_40942691_40943841	0.07	ZFP69	ZFP69 zinc finger protein	36	0.96
chr17_73521710_73521861	0.07	LLGL2	lethal giant larvae homolog 2 (Drosophila)	22	0.96
chr17_1962412_1962588	0.07	HIC1	hypermethylated in cancer 1	2896	0.12
chr2_243030793_243031816	0.07	AC093642.5		460	0.62
chr17_79848117_79849118	0.07	ANAPC11	anaphase promoting complex subunit 11	49	0.89
chr10_15138786_15140121	0.07	RPP38	ribonuclease P/MRP 38kDa subunit	34	0.62
chr4_1341026_1341962	0.07	UVSSA	UV-stimulated scaffold protein A	0	0.97
chr5_32522838_32523035	0.07	SUB1	SUB1 homolog (S. cerevisiae)	8803	0.26
chr1_146714369_146715035	0.07	CHD1L	chromodomain helicase DNA binding protein 1-like	346	0.88
chr1_246952376_246952607	0.07	ENSG00000227953	.	1435	0.37
chrX_103357104_103358067	0.07	ZCCHC18	zinc finger, CCHC domain containing 18	383	0.86
chr15_90294233_90294789	0.07	MESP1	mesoderm posterior 1 homolog (mouse)	30	0.96
chr11_48002643_48003787	0.07	PTPRJ	protein tyrosine phosphatase, receptor type, J	936	0.61
chr9_35489468_35490886	0.07	RUSC2	RUN and SH3 domain containing 2	53	0.97
chr5_176432878_176433695	0.07	UIMC1	ubiquitin interaction motif containing 1	123	0.96
chr1_1207989_1209115	0.07	UBE2J2	ubiquitin-conjugating enzyme E2, J2	299	0.76
chr18_3262315_3263346	0.07	MYL12B	myosin, light chain 12B, regulatory	124	0.92
chr8_145747877_145748779	0.07	LRRC24	leucine rich repeat containing 24	4074	0.07
chr17_37856067_37857084	0.07	ERBB2	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2	242	0.86
chr5_138089111_138089974	0.07	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	192	0.8
chr17_34611752_34612896	0.07	CCL3L1	chemokine (C-C motif) ligand 3-like 1	13395	0.14
chr17_235901_236198	0.07	RPH3AL	rabphilin 3A-like (without C2 domains)	4	0.97
chr3_8809480_8810320	0.07	OXTR	oxytocin receptor	463	0.76
chr19_36545772_36546481	0.07	WDR62	WD repeat domain 62	234	0.67
chr17_36508115_36509219	0.07	SOCS7	suppressor of cytokine signaling 7	159	0.94
chr9_91926364_91927170	0.07	ENSG00000265112	.	373	0.66
chr3_181413371_181413945	0.07	SOX2-OT	SOX2 overlapping transcript (non-protein coding)	3623	0.29
chrX_9432622_9433173	0.07	TBL1X	transducin (beta)-like 1X-linked	151	0.98
chr17_29814991_29815971	0.07	RAB11FIP4	RAB11 family interacting protein 4 (class II)	355	0.83
chrX_131622714_131623644	0.07	MBNL3	muscleblind-like splicing regulator 3	136	0.98
chr15_95388341_95388759	0.07	MCTP2	multiple C2 domains, transmembrane 2	489347	0.01
chr3_75707498_75708269	0.07	FRG2C	FSHD region gene 2 family, member C	5598	0.22
chr2_121102314_121103173	0.07	INHBB	inhibin, beta B	976	0.66
chr15_62360405_62361178	0.07	C2CD4A	C2 calcium-dependent domain containing 4A	1615	0.36
chr7_29605545_29606286	0.07	PRR15	proline rich 15	849	0.6
chr14_106347518_106347669	0.07	ENSG00000225825	.	179	0.62
chr9_140500205_140501463	0.07	ARRDC1	arrestin domain containing 1	679	0.56
chr3_128210659_128211025	0.07	GATA2	GATA binding protein 2	1174	0.41
chr7_26437839_26438861	0.07	AC004540.4		22029	0.21
chr4_8632079_8632376	0.07	CPZ	carboxypeptidase Z	28530	0.2
chr12_117036919_117037510	0.07	MAP1LC3B2	microtubule-associated protein 1 light chain 3 beta 2	23558	0.24
chr13_20766378_20767168	0.06	GJB2	gap junction protein, beta 2, 26kDa	264	0.91
chr8_27491561_27492240	0.06	SCARA3	scavenger receptor class A, member 3	202	0.93
chr11_118305386_118306890	0.06	RP11-770J1.4		217	0.83
chr9_133813639_133813991	0.06	FIBCD1	fibrinogen C domain containing 1	422	0.82
chr4_77342002_77342745	0.06	SHROOM3	shroom family member 3	13880	0.15
chr17_40332753_40333403	0.06	KCNH4	potassium voltage-gated channel, subfamily H (eag-related), member 4	21	0.95
chr10_49732228_49732379	0.06	ARHGAP22	Rho GTPase activating protein 22	22	0.98
chr19_15489473_15490549	0.06	ENSG00000268189	.	112	0.87
chr22_17601691_17602165	0.06	CECR6	cat eye syndrome chromosome region, candidate 6	215	0.77
chrX_109246139_109246998	0.06	TMEM164	transmembrane protein 164	225	0.95
chr12_95043269_95044318	0.06	TMCC3	transmembrane and coiled-coil domain family 3	545	0.85
chr7_150783520_150783695	0.06	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	222	0.85
chr7_75986838_75988224	0.06	YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	817	0.59
chr11_75479321_75480435	0.06	DGAT2	diacylglycerol O-acyltransferase 2	21	0.69
chr12_52263267_52263773	0.06	ANKRD33	ankyrin repeat domain 33	18224	0.17
chr11_73019949_73020282	0.06	RP11-800A3.7		291	0.76
chr4_118954790_118955212	0.06	NDST3	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3	499	0.89
chr1_206831789_206831940	0.06	DYRK3	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3	22690	0.12
chr5_76475983_76476746	0.06	PDE8B	phosphodiesterase 8B	29910	0.15
chr20_32030739_32031661	0.06	SNTA1	syntrophin, alpha 1	498	0.77
chr11_61595087_61595308	0.06	FADS2	fatty acid desaturase 2	36	0.95
chr1_247694177_247694328	0.06	OR2C3	olfactory receptor, family 2, subfamily C, member 3	2889	0.17
chr1_45278722_45278873	0.06	BTBD19	BTB (POZ) domain containing 19	4602	0.08
chr1_223743422_223744240	0.06	CAPN8	calpain 8	19451	0.25
chr11_62367822_62369222	0.06	MTA2	metastasis associated 1 family, member 2	225	0.8
chr12_111051969_111052303	0.06	TCTN1	tectonic family member 1	167	0.94
chr1_244816518_244817656	0.06	DESI2	desumoylating isopeptidase 2	34	0.98
chr7_155601099_155601405	0.06	SHH	sonic hedgehog	514	0.83
chr12_26348638_26349346	0.06	SSPN	sarcospan	386	0.88
chr12_124155530_124156430	0.06	TCTN2	tectonic family member 2	320	0.85
chr15_41851700_41852372	0.06	TYRO3	TYRO3 protein tyrosine kinase	804	0.57
chr1_6672501_6673393	0.06	PHF13	PHD finger protein 13	798	0.46
chr18_77547944_77548277	0.06	KCNG2	potassium voltage-gated channel, subfamily G, member 2	75558	0.1
chrX_153639895_153640843	0.06	DNASE1L1	deoxyribonuclease I-like 1	51	0.66
chrX_12156590_12157176	0.06	FRMPD4	FERM and PDZ domain containing 4	298	0.9
chr15_56034170_56035376	0.06	PRTG	protogenin	41	0.98
chr19_57828794_57829125	0.06	ZNF543	zinc finger protein 543	2918	0.14
chr8_28269075_28269620	0.06	ENSG00000207361	.	4618	0.15
chr11_14665333_14666638	0.06	PDE3B	phosphodiesterase 3B, cGMP-inhibited	608	0.56
chr12_133263459_133264038	0.06	POLE	polymerase (DNA directed), epsilon, catalytic subunit	166	0.73
chr6_18277489_18278102	0.06	ENSG00000199715	.	4298	0.21
chr9_138987258_138988057	0.06	NACC2	NACC family member 2, BEN and BTB (POZ) domain containing	526	0.8
chr10_88280283_88281468	0.06	WAPAL	wings apart-like homolog (Drosophila)	697	0.48
chr12_106640524_106641264	0.06	RP11-651L5.2		160	0.9
chr6_41702621_41703238	0.06	TFEB	transcription factor EB	131	0.93
chr9_123837276_123837840	0.06	CNTRL	centriolin	268	0.93
chr10_116634887_116635113	0.06	FAM160B1	family with sequence similarity 160, member B1	14450	0.25
chr7_145813891_145814290	0.06	CNTNAP2	contactin associated protein-like 2	637	0.8
chr1_2005099_2005545	0.06	PRKCZ	protein kinase C, zeta	103	0.96
chr16_89766857_89768141	0.06	SPATA2L	spermatogenesis associated 2-like	549	0.59
chr7_99595147_99595680	0.06	AZGP1P1	alpha-2-glycoprotein 1, zinc-binding pseudogene 1	17024	0.08
chr9_127240198_127240462	0.06	NR5A1	nuclear receptor subfamily 5, group A, member 1	22935	0.17
chr2_120189452_120190154	0.06	TMEM37	transmembrane protein 37	358	0.88
chr1_246948051_246948632	0.06	ENSG00000227953	.	5585	0.17
chr11_117185897_117186711	0.06	BACE1	beta-site APP-cleaving enzyme 1	210	0.87
chr3_126076169_126076320	0.06	KLF15	Kruppel-like factor 15	41	0.98
chr12_54589848_54590188	0.06	SMUG1	single-strand-selective monofunctional uracil-DNA glycosylase 1	7240	0.12
chr4_47916858_47917055	0.06	NFXL1	nuclear transcription factor, X-box binding-like 1	323	0.9

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.2	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.0	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.1	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.0	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.0	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.1	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.0	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.1	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.0	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.1	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.0	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0051136	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0043218	compact myelin(GO:0043218)
0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	GO:0005915	zonula adherens(GO:0005915)
0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.1	GO:0031512	motile primary cilium(GO:0031512)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.0	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.0	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.0	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.0	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.0	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.0	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.0	REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL	Genes involved in Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters