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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for MBD2

Z-value: 0.57

Motif logo

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Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
MBD2
ENSG00000134046.7 methyl-CpG binding domain protein 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr18_51751599_51751750MBD25160.785603-0.853.8e-03Click!
chr18_51766045_51766196MBD2149620.1862170.383.1e-01Click!
chr18_51749801_51749975MBD210990.380751-0.324.0e-01Click!
chr18_51750360_51750511MBD25520.724562-0.137.3e-01Click!
chr18_51751166_51751526MBD21880.944061-0.137.3e-01Click!

Activity of the MBD2 motif across conditions

Conditions sorted by the z-value of the MBD2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_80189068_80189889 0.26 SLC16A3
 solute carrier family 16 (monocarboxylate transporter), member 3
 630
 0.57
chr6_166721057_166722024 0.25 PRR18
 proline rich 18
 331
 0.9
chr4_74809740_74810515 0.22 PF4
 platelet factor 4
 37714
 0.11
chr3_36985452_36986747 0.20 TRANK1
 tetratricopeptide repeat and ankyrin repeat containing 1
 449
 0.83
chr12_3308931_3310293 0.19 TSPAN9
 tetraspanin 9
 729
 0.75
chr3_142681892_142682427 0.19 PAQR9
 progestin and adipoQ receptor family member IX
 19
 0.84
chr20_43729394_43729952 0.19 KCNS1
 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
 77
 0.96
chr21_44496501_44497065 0.18 CBS
 cystathionine-beta-synthase
 270
 0.91
chrX_48748285_48749195 0.17 TIMM17B
 translocase of inner mitochondrial membrane 17 homolog B (yeast)
 6290
 0.1
chr2_27485345_27486489 0.17 SLC30A3
 solute carrier family 30 (zinc transporter), member 3
 178
 0.89
chr3_196594834_196595961 0.17 SENP5
 SUMO1/sentrin specific peptidase 5
 581
 0.72
chr10_94449633_94450257 0.16 HHEX
 hematopoietically expressed homeobox
 898
 0.6
chr3_192126971_192127690 0.15 FGF12
 fibroblast growth factor 12
 492
 0.87
chr18_70210992_70211675 0.15 CBLN2
 cerebellin 2 precursor
 441
 0.91
chr7_128171824_128173030 0.15 RP11-274B21.1
1279
 0.43
chr5_149864820_149865733 0.14 NDST1
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
 105
 0.97
chr10_98592747_98593792 0.14 LCOR
 ligand dependent nuclear receptor corepressor
 532
 0.78
chr3_39194337_39194962 0.14 CSRNP1
 cysteine-serine-rich nuclear protein 1
 417
 0.84
chr15_56035451_56035609 0.14 PRTG
 protogenin
 242
 0.94
chr17_78234751_78235551 0.14 RNF213
 ring finger protein 213
 482
 0.76
chr4_71570546_71572213 0.13 RUFY3
 RUN and FYVE domain containing 3
 861
 0.36
chr5_74907170_74908023 0.13 ANKDD1B
 ankyrin repeat and death domain containing 1B
 312
 0.9
chr2_185463143_185463634 0.13 ZNF804A
 zinc finger protein 804A
 295
 0.95
chr13_29068702_29069490 0.13 FLT1
 fms-related tyrosine kinase 1
 136
 0.98
chr17_73584494_73585142 0.13 MYO15B
 myosin XVB pseudogene
 2040
 0.21
chrX_39964334_39965624 0.13 BCOR
 BCL6 corepressor
 8323
 0.32
chr1_180881914_180882730 0.12 KIAA1614
 KIAA1614
 3
 0.98
chr3_195384928_195385957 0.12 SDHAP2
 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
 475
 0.81
chr15_99192776_99194432 0.12 IGF1R
 insulin-like growth factor 1 receptor
 1331
 0.47
chr17_20491916_20492779 0.12 CDRT15L2
 CMT1A duplicated region transcript 15-like 2
 9310
 0.21
chr16_691284_692401 0.12 FAM195A
 family with sequence similarity 195, member A
 29
 0.92
chr2_160653969_160654659 0.11 CD302
 CD302 molecule
 439
 0.87
chr22_20003723_20004755 0.11 ARVCF
 armadillo repeat gene deleted in velocardiofacial syndrome
 92
 0.75
chr21_37529152_37530122 0.11 DOPEY2
 dopey family member 2
 557
 0.57
chr14_100706520_100706671 0.11 YY1
 YY1 transcription factor
 499
 0.64
chr22_29601932_29602692 0.11 EMID1
 EMI domain containing 1
 400
 0.8
chr8_144512945_144513817 0.11 MAFA
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
 805
 0.48
chr5_134825154_134825603 0.11 TIFAB
 TRAF-interacting protein with forkhead-associated domain, family member B
 37289
 0.11
chr18_77558508_77558774 0.10 KCNG2
 potassium voltage-gated channel, subfamily G, member 2
 65027
 0.12
chr18_11149170_11149978 0.10 PIEZO2
 piezo-type mechanosensitive ion channel component 2
 987
 0.72
chr7_2394785_2395825 0.10 EIF3B
 eukaryotic translation initiation factor 3, subunit B
 788
 0.53
chr10_102278895_102279852 0.10 SEC31B
 SEC31 homolog B (S. cerevisiae)
 218
 0.92
chr11_62455448_62455813 0.10 LRRN4CL
 LRRN4 C-terminal like
 1741
 0.12
chr11_119019412_119020504 0.10 ABCG4
 ATP-binding cassette, sub-family G (WHITE), member 4
 5
 0.94
chr3_141379125_141379497 0.10 RNF7
 ring finger protein 7
 77735
 0.09
chr13_21634768_21635319 0.10 LATS2
 large tumor suppressor kinase 2
 614
 0.69
chr19_10982465_10983821 0.10 CARM1
 coactivator-associated arginine methyltransferase 1
 764
 0.53
chr3_197463352_197463883 0.10 KIAA0226
 KIAA0226
 27
 0.88
chr2_8818889_8820001 0.10 AC011747.7
259
 0.7
chrX_36975622_36976198 0.10 FAM47C
 family with sequence similarity 47, member C
 50522
 0.19
chrX_53349448_53350467 0.10 IQSEC2
 IQ motif and Sec7 domain 2
 565
 0.73
chr15_69113585_69114214 0.10 ANP32A
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
 665
 0.75
chr11_63535609_63536120 0.09 ENSG00000264519
 .
 29679
 0.13
chr20_3073179_3074190 0.09 ENSG00000263905
 .
 1177
 0.34
chr1_159750747_159751482 0.09 DUSP23
 dual specificity phosphatase 23
 321
 0.85
chr18_74843262_74844680 0.09 MBP
 myelin basic protein
 331
 0.94
chrX_119384747_119385998 0.09 ZBTB33
 zinc finger and BTB domain containing 33
 762
 0.69
chr12_6937518_6938631 0.09 LEPREL2
 leprecan-like 2
 502
 0.55
chr2_103235205_103235939 0.09 SLC9A2
 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
 594
 0.82
chr12_14720104_14720509 0.09 RP11-695J4.2
378
 0.73
chr16_66638822_66640143 0.09 CMTM3
 CKLF-like MARVEL transmembrane domain containing 3
 58
 0.95
chr5_42944152_42944647 0.09 SEPP1
 selenoprotein P, plasma, 1
 56905
 0.11
chr5_76506770_76507546 0.09 PDE8B
 phosphodiesterase 8B
 407
 0.88
chr1_17446030_17446253 0.09 PADI2
 peptidyl arginine deiminase, type II
 193
 0.94
chr16_70221940_70222878 0.09 CLEC18C
 C-type lectin domain family 18, member C
 14349
 0.1
chr4_128543868_128544388 0.09 INTU
 inturned planar cell polarity protein
 298
 0.94
chr1_45008521_45008672 0.09 ENSG00000263381
 .
 2569
 0.31
chr7_18125753_18126403 0.08 HDAC9
 histone deacetylase 9
 494
 0.84
chr1_36923329_36923682 0.08 MRPS15
 mitochondrial ribosomal protein S15
 6533
 0.14
chr6_85472920_85473300 0.08 TBX18
 T-box 18
 37
 0.99
chr20_49347136_49348386 0.08 PARD6B
 par-6 family cell polarity regulator beta
 320
 0.89
chr1_103573929_103574109 0.08 COL11A1
 collagen, type XI, alpha 1
 16
 0.99
chr20_32273512_32274295 0.08 E2F1
 E2F transcription factor 1
 307
 0.81
chr14_101034010_101035263 0.08 BEGAIN
 brain-enriched guanylate kinase-associated
 192
 0.93
chr8_142138821_142140144 0.08 RP11-809O17.1
578
 0.46
chr5_133861629_133862874 0.08 JADE2
 jade family PHD finger 2
 76
 0.97
chr9_77501796_77502826 0.08 TRPM6
 transient receptor potential cation channel, subfamily M, member 6
 48
 0.97
chr13_114822852_114823008 0.08 RASA3
 RAS p21 protein activator 3
 20508
 0.23
chr18_499765_500605 0.08 COLEC12
 collectin sub-family member 12
 537
 0.79
chr20_31351193_31351609 0.08 DNMT3B
 DNA (cytosine-5-)-methyltransferase 3 beta
 953
 0.56
chr11_68780491_68780695 0.08 MRGPRF
 MAS-related GPR, member F
 121
 0.88
chr20_39657787_39658990 0.08 TOP1
 topoisomerase (DNA) I
 930
 0.61
chr13_27131903_27132772 0.08 WASF3
 WAS protein family, member 3
 450
 0.89
chr10_27547544_27548544 0.08 ARMC4P1
 armadillo repeat containing 4 pseudogene 1
 3842
 0.17
chr3_195635375_195636127 0.08 TNK2
 tyrosine kinase, non-receptor, 2
 204
 0.83
chr10_6186918_6187892 0.08 PFKFB3
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
 508
 0.72
chr8_67624599_67625774 0.08 SGK3
 serum/glucocorticoid regulated kinase family, member 3
 533
 0.76
chr17_79268296_79269061 0.08 SLC38A10
 solute carrier family 38, member 10
 389
 0.8
chr7_92218956_92219793 0.08 FAM133B
 family with sequence similarity 133, member B
 10
 0.98
chr13_99227754_99228977 0.08 STK24
 serine/threonine kinase 24
 752
 0.54
chr1_53685385_53686250 0.08 C1orf123
 chromosome 1 open reading frame 123
 472
 0.43
chr17_38498589_38499681 0.08 CTD-2267D19.2
253
 0.69
chr16_85793355_85793506 0.08 C16orf74
 chromosome 16 open reading frame 74
 8695
 0.11
chr4_682374_683342 0.07 MFSD7
 major facilitator superfamily domain containing 7
 74
 0.94
chr18_12376105_12377115 0.07 AFG3L2
 AFG3-like AAA ATPase 2
 391
 0.83
chr5_1110808_1112337 0.07 SLC12A7
 solute carrier family 12 (potassium/chloride transporter), member 7
 578
 0.75
chr10_27148230_27149879 0.07 ABI1
 abl-interactor 1
 738
 0.67
chr17_2296252_2297077 0.07 MNT
 MAX network transcriptional repressor
 7734
 0.11
chr6_7051751_7052548 0.07 ENSG00000251762
 .
 11370
 0.24
chr7_127671114_127671650 0.07 LRRC4
 leucine rich repeat containing 4
 259
 0.94
chr8_136470073_136470726 0.07 KHDRBS3
 KH domain containing, RNA binding, signal transduction associated 3
 69
 0.96
chr1_40942691_40943841 0.07 ZFP69
 ZFP69 zinc finger protein
 36
 0.96
chr17_73521710_73521861 0.07 LLGL2
 lethal giant larvae homolog 2 (Drosophila)
 22
 0.96
chr17_1962412_1962588 0.07 HIC1
 hypermethylated in cancer 1
 2896
 0.12
chr2_243030793_243031816 0.07 AC093642.5
460
 0.62
chr17_79848117_79849118 0.07 ANAPC11
 anaphase promoting complex subunit 11
 49
 0.89
chr10_15138786_15140121 0.07 RPP38
 ribonuclease P/MRP 38kDa subunit
 34
 0.62
chr4_1341026_1341962 0.07 UVSSA
 UV-stimulated scaffold protein A
 0
 0.97
chr5_32522838_32523035 0.07 SUB1
 SUB1 homolog (S. cerevisiae)
 8803
 0.26
chr1_146714369_146715035 0.07 CHD1L
 chromodomain helicase DNA binding protein 1-like
 346
 0.88
chr1_246952376_246952607 0.07 ENSG00000227953
 .
 1435
 0.37
chrX_103357104_103358067 0.07 ZCCHC18
 zinc finger, CCHC domain containing 18
 383
 0.86
chr15_90294233_90294789 0.07 MESP1
 mesoderm posterior 1 homolog (mouse)
 30
 0.96
chr11_48002643_48003787 0.07 PTPRJ
 protein tyrosine phosphatase, receptor type, J
 936
 0.61
chr9_35489468_35490886 0.07 RUSC2
 RUN and SH3 domain containing 2
 53
 0.97
chr5_176432878_176433695 0.07 UIMC1
 ubiquitin interaction motif containing 1
 123
 0.96
chr1_1207989_1209115 0.07 UBE2J2
 ubiquitin-conjugating enzyme E2, J2
 299
 0.76
chr18_3262315_3263346 0.07 MYL12B
 myosin, light chain 12B, regulatory
 124
 0.92
chr8_145747877_145748779 0.07 LRRC24
 leucine rich repeat containing 24
 4074
 0.07
chr17_37856067_37857084 0.07 ERBB2
 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
 242
 0.86
chr5_138089111_138089974 0.07 CTNNA1
 catenin (cadherin-associated protein), alpha 1, 102kDa
 192
 0.8
chr17_34611752_34612896 0.07 CCL3L1
 chemokine (C-C motif) ligand 3-like 1
 13395
 0.14
chr17_235901_236198 0.07 RPH3AL
 rabphilin 3A-like (without C2 domains)
 4
 0.97
chr3_8809480_8810320 0.07 OXTR
 oxytocin receptor
 463
 0.76
chr19_36545772_36546481 0.07 WDR62
 WD repeat domain 62
 234
 0.67
chr17_36508115_36509219 0.07 SOCS7
 suppressor of cytokine signaling 7
 159
 0.94
chr9_91926364_91927170 0.07 ENSG00000265112
 .
 373
 0.66
chr3_181413371_181413945 0.07 SOX2-OT
 SOX2 overlapping transcript (non-protein coding)
 3623
 0.29
chrX_9432622_9433173 0.07 TBL1X
 transducin (beta)-like 1X-linked
 151
 0.98
chr17_29814991_29815971 0.07 RAB11FIP4
 RAB11 family interacting protein 4 (class II)
 355
 0.83
chrX_131622714_131623644 0.07 MBNL3
 muscleblind-like splicing regulator 3
 136
 0.98
chr15_95388341_95388759 0.07 MCTP2
 multiple C2 domains, transmembrane 2
 489347
 0.01
chr3_75707498_75708269 0.07 FRG2C
 FSHD region gene 2 family, member C
 5598
 0.22
chr2_121102314_121103173 0.07 INHBB
 inhibin, beta B
 976
 0.66
chr15_62360405_62361178 0.07 C2CD4A
 C2 calcium-dependent domain containing 4A
 1615
 0.36
chr7_29605545_29606286 0.07 PRR15
 proline rich 15
 849
 0.6
chr14_106347518_106347669 0.07 ENSG00000225825
 .
 179
 0.62
chr9_140500205_140501463 0.07 ARRDC1
 arrestin domain containing 1
 679
 0.56
chr3_128210659_128211025 0.07 GATA2
 GATA binding protein 2
 1174
 0.41
chr7_26437839_26438861 0.07 AC004540.4
22029
 0.21
chr4_8632079_8632376 0.07 CPZ
 carboxypeptidase Z
 28530
 0.2
chr12_117036919_117037510 0.07 MAP1LC3B2
 microtubule-associated protein 1 light chain 3 beta 2
 23558
 0.24
chr13_20766378_20767168 0.06 GJB2
 gap junction protein, beta 2, 26kDa
 264
 0.91
chr8_27491561_27492240 0.06 SCARA3
 scavenger receptor class A, member 3
 202
 0.93
chr11_118305386_118306890 0.06 RP11-770J1.4
217
 0.83
chr9_133813639_133813991 0.06 FIBCD1
 fibrinogen C domain containing 1
 422
 0.82
chr4_77342002_77342745 0.06 SHROOM3
 shroom family member 3
 13880
 0.15
chr17_40332753_40333403 0.06 KCNH4
 potassium voltage-gated channel, subfamily H (eag-related), member 4
 21
 0.95
chr10_49732228_49732379 0.06 ARHGAP22
 Rho GTPase activating protein 22
 22
 0.98
chr19_15489473_15490549 0.06 ENSG00000268189
 .
 112
 0.87
chr22_17601691_17602165 0.06 CECR6
 cat eye syndrome chromosome region, candidate 6
 215
 0.77
chrX_109246139_109246998 0.06 TMEM164
 transmembrane protein 164
 225
 0.95
chr12_95043269_95044318 0.06 TMCC3
 transmembrane and coiled-coil domain family 3
 545
 0.85
chr7_150783520_150783695 0.06 AGAP3
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
 222
 0.85
chr7_75986838_75988224 0.06 YWHAG
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
 817
 0.59
chr11_75479321_75480435 0.06 DGAT2
 diacylglycerol O-acyltransferase 2
 21
 0.69
chr12_52263267_52263773 0.06 ANKRD33
 ankyrin repeat domain 33
 18224
 0.17
chr11_73019949_73020282 0.06 RP11-800A3.7
291
 0.76
chr4_118954790_118955212 0.06 NDST3
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
 499
 0.89
chr1_206831789_206831940 0.06 DYRK3
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
 22690
 0.12
chr5_76475983_76476746 0.06 PDE8B
 phosphodiesterase 8B
 29910
 0.15
chr20_32030739_32031661 0.06 SNTA1
 syntrophin, alpha 1
 498
 0.77
chr11_61595087_61595308 0.06 FADS2
 fatty acid desaturase 2
 36
 0.95
chr1_247694177_247694328 0.06 OR2C3
 olfactory receptor, family 2, subfamily C, member 3
 2889
 0.17
chr1_45278722_45278873 0.06 BTBD19
 BTB (POZ) domain containing 19
 4602
 0.08
chr1_223743422_223744240 0.06 CAPN8
 calpain 8
 19451
 0.25
chr11_62367822_62369222 0.06 MTA2
 metastasis associated 1 family, member 2
 225
 0.8
chr12_111051969_111052303 0.06 TCTN1
 tectonic family member 1
 167
 0.94
chr1_244816518_244817656 0.06 DESI2
 desumoylating isopeptidase 2
 34
 0.98
chr7_155601099_155601405 0.06 SHH
 sonic hedgehog
 514
 0.83
chr12_26348638_26349346 0.06 SSPN
 sarcospan
 386
 0.88
chr12_124155530_124156430 0.06 TCTN2
 tectonic family member 2
 320
 0.85
chr15_41851700_41852372 0.06 TYRO3
 TYRO3 protein tyrosine kinase
 804
 0.57
chr1_6672501_6673393 0.06 PHF13
 PHD finger protein 13
 798
 0.46
chr18_77547944_77548277 0.06 KCNG2
 potassium voltage-gated channel, subfamily G, member 2
 75558
 0.1
chrX_153639895_153640843 0.06 DNASE1L1
 deoxyribonuclease I-like 1
 51
 0.66
chrX_12156590_12157176 0.06 FRMPD4
 FERM and PDZ domain containing 4
 298
 0.9
chr15_56034170_56035376 0.06 PRTG
 protogenin
 41
 0.98
chr19_57828794_57829125 0.06 ZNF543
 zinc finger protein 543
 2918
 0.14
chr8_28269075_28269620 0.06 ENSG00000207361
 .
 4618
 0.15
chr11_14665333_14666638 0.06 PDE3B
 phosphodiesterase 3B, cGMP-inhibited
 608
 0.56
chr12_133263459_133264038 0.06 POLE
 polymerase (DNA directed), epsilon, catalytic subunit
 166
 0.73
chr6_18277489_18278102 0.06 ENSG00000199715
 .
 4298
 0.21
chr9_138987258_138988057 0.06 NACC2
 NACC family member 2, BEN and BTB (POZ) domain containing
 526
 0.8
chr10_88280283_88281468 0.06 WAPAL
 wings apart-like homolog (Drosophila)
 697
 0.48
chr12_106640524_106641264 0.06 RP11-651L5.2
160
 0.9
chr6_41702621_41703238 0.06 TFEB
 transcription factor EB
 131
 0.93
chr9_123837276_123837840 0.06 CNTRL
 centriolin
 268
 0.93
chr10_116634887_116635113 0.06 FAM160B1
 family with sequence similarity 160, member B1
 14450
 0.25
chr7_145813891_145814290 0.06 CNTNAP2
 contactin associated protein-like 2
 637
 0.8
chr1_2005099_2005545 0.06 PRKCZ
 protein kinase C, zeta
 103
 0.96
chr16_89766857_89768141 0.06 SPATA2L
 spermatogenesis associated 2-like
 549
 0.59
chr7_99595147_99595680 0.06 AZGP1P1
 alpha-2-glycoprotein 1, zinc-binding pseudogene 1
 17024
 0.08
chr9_127240198_127240462 0.06 NR5A1
 nuclear receptor subfamily 5, group A, member 1
 22935
 0.17
chr2_120189452_120190154 0.06 TMEM37
 transmembrane protein 37
 358
 0.88
chr1_246948051_246948632 0.06 ENSG00000227953
 .
 5585
 0.17
chr11_117185897_117186711 0.06 BACE1
 beta-site APP-cleaving enzyme 1
 210
 0.87
chr3_126076169_126076320 0.06 KLF15
 Kruppel-like factor 15
 41
 0.98
chr12_54589848_54590188 0.06 SMUG1
 single-strand-selective monofunctional uracil-DNA glycosylase 1
 7240
 0.12
chr4_47916858_47917055 0.06 NFXL1
 nuclear transcription factor, X-box binding-like 1
 323
 0.9

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.0 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.0 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0044321 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0051136 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.0 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.0 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.0 REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL Genes involved in Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters