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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for MEF2B

Z-value: 0.75

Motif logo

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Transcription factors associated with MEF2B

Gene Symbol Gene ID Gene Info
ENSG00000213999.11 MEF2B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
MEF2Bchr19_19280776_192811291020.937982-0.412.7e-01Click!
MEF2Bchr19_19281413_192815643900.7455180.304.4e-01Click!
MEF2Bchr19_19281195_192814052020.8875960.245.3e-01Click!
MEF2Bchr19_19282584_1928273515610.2352750.147.2e-01Click!
MEF2Bchr19_19283135_1928328621120.1783750.117.7e-01Click!

Activity of the MEF2B motif across conditions

Conditions sorted by the z-value of the MEF2B motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_17699920_17700290 0.69 RAD51AP2
RAD51 associated protein 2
399
0.89
chr1_234630809_234631231 0.67 TARBP1
TAR (HIV-1) RNA binding protein 1
16171
0.21
chr20_11871763_11872529 0.63 BTBD3
BTB (POZ) domain containing 3
171
0.97
chr6_86167890_86168219 0.62 NT5E
5'-nucleotidase, ecto (CD73)
8227
0.28
chr11_94503028_94503179 0.61 AMOTL1
angiomotin like 1
1566
0.45
chr14_89769991_89770787 0.59 RP11-356K23.1

46240
0.14
chr11_43597772_43598095 0.57 ENSG00000199077
.
5011
0.24
chr9_124360553_124361088 0.55 RP11-524G24.2

22327
0.18
chr2_155312257_155312697 0.54 AC009227.2

1473
0.49
chr3_145968218_145968873 0.53 PLSCR4
phospholipid scramblase 4
109
0.98
chr6_49293859_49294324 0.50 ENSG00000252457
.
18430
0.26
chr5_39399204_39399669 0.50 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
4934
0.29
chr1_151173034_151173185 0.46 PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
2058
0.17
chr16_88449218_88449497 0.45 ZNF469
zinc finger protein 469
44522
0.14
chr1_93818876_93819027 0.44 ENSG00000223745
.
7369
0.19
chr9_81322437_81322726 0.44 PSAT1
phosphoserine aminotransferase 1
410522
0.01
chr11_113649028_113649338 0.41 CLDN25
claudin 25
1286
0.35
chr1_229762768_229763169 0.40 URB2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
987
0.42
chr8_6539493_6539644 0.38 CTD-2541M15.1

26132
0.18
chr12_109219039_109219464 0.37 SSH1
slingshot protein phosphatase 1
811
0.57
chr9_127999236_127999759 0.37 HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
4112
0.17
chr6_106994674_106995055 0.37 AIM1
absent in melanoma 1
5835
0.22
chr1_50575996_50576351 0.36 ELAVL4
ELAV like neuron-specific RNA binding protein 4
795
0.71
chr2_55226424_55226816 0.35 RTN4
reticulon 4
10965
0.21
chr13_45011783_45011934 0.35 TSC22D1
TSC22 domain family, member 1
877
0.72
chr19_8305457_8305834 0.34 CTD-3020H12.4

1113
0.43
chr2_98487283_98487560 0.33 TMEM131
transmembrane protein 131
36288
0.17
chr5_14154391_14154790 0.32 TRIO
trio Rho guanine nucleotide exchange factor
10761
0.32
chr20_62485470_62485890 0.31 ABHD16B
abhydrolase domain containing 16B
6886
0.08
chr17_27719677_27719955 0.31 TAOK1
TAO kinase 1
1867
0.18
chr5_88081859_88082385 0.30 MEF2C
myocyte enhancer factor 2C
37483
0.19
chrX_77908364_77908810 0.29 ZCCHC5
zinc finger, CCHC domain containing 5
6238
0.32
chr3_66139685_66140118 0.29 SLC25A26
solute carrier family 25 (S-adenosylmethionine carrier), member 26
20616
0.25
chr1_24373488_24373760 0.28 RP11-293P20.2

6299
0.15
chr17_65428016_65428233 0.28 ENSG00000201547
.
23127
0.12
chr22_46366779_46367595 0.28 WNT7B
wingless-type MMTV integration site family, member 7B
1408
0.38
chr3_29377379_29377667 0.28 ENSG00000216169
.
33389
0.18
chr3_99357829_99358140 0.28 COL8A1
collagen, type VIII, alpha 1
530
0.85
chr3_48597891_48598569 0.27 PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
332
0.77
chr8_56805751_56805987 0.27 RP11-318K15.2

285
0.88
chr6_26698405_26698556 0.26 ZNF322
zinc finger protein 322
38500
0.16
chr15_99864560_99864718 0.26 AC022819.2
Uncharacterized protein
4811
0.23
chr2_55345979_55346130 0.26 RTN4
reticulon 4
6297
0.2
chr2_174983381_174983564 0.26 OLA1
Obg-like ATPase 1
99202
0.07
chr9_108211383_108211534 0.26 FSD1L
fibronectin type III and SPRY domain containing 1-like
1054
0.64
chr18_3579974_3580125 0.26 ENSG00000238445
.
7008
0.16
chr1_184476918_184477069 0.25 GS1-115G20.1

99522
0.07
chr1_10168624_10168775 0.25 UBE4B
ubiquitination factor E4B
13401
0.19
chr21_30504177_30504355 0.25 MAP3K7CL
MAP3K7 C-terminal like
688
0.61
chr4_183167608_183167774 0.25 TENM3
teneurin transmembrane protein 3
3109
0.34
chr18_43840452_43840603 0.24 RNF165
ring finger protein 165
66245
0.11
chr4_41362274_41362647 0.24 LIMCH1
LIM and calponin homology domains 1
188
0.96
chr11_85429273_85429899 0.24 SYTL2
synaptotagmin-like 2
55
0.97
chr10_134401745_134402170 0.24 INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
19473
0.23
chr14_89631722_89632070 0.24 FOXN3
forkhead box N3
15192
0.28
chr7_121012824_121012975 0.24 FAM3C
family with sequence similarity 3, member C
23463
0.22
chr2_122258317_122258683 0.24 CLASP1
cytoplasmic linker associated protein 1
3064
0.27
chr1_201819395_201819711 0.24 IPO9-AS1
IPO9 antisense RNA 1
20866
0.11
chr5_65750356_65750571 0.23 MAST4
microtubule associated serine/threonine kinase family member 4
141713
0.05
chr2_238571219_238571370 0.23 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
29494
0.17
chr14_34145464_34145720 0.23 NPAS3
neuronal PAS domain protein 3
58855
0.17
chr17_42172843_42173098 0.23 HDAC5
histone deacetylase 5
2415
0.15
chr1_17945358_17945612 0.23 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
636
0.82
chr5_52098224_52098443 0.22 CTD-2288O8.1

14473
0.19
chr2_145695991_145696253 0.22 ENSG00000253036
.
396516
0.01
chr3_24527242_24527393 0.22 ENSG00000228791
.
8261
0.19
chr12_50504495_50504703 0.22 COX14
cytochrome c oxidase assembly homolog 14 (S. cerevisiae)
1163
0.28
chr17_41669450_41669625 0.22 ETV4
ets variant 4
12549
0.16
chr4_15011908_15012097 0.22 CPEB2
cytoplasmic polyadenylation element binding protein 2
6442
0.31
chr13_44642585_44642983 0.22 SMIM2-AS1
SMIM2 antisense RNA 1
73898
0.1
chr21_39678468_39679041 0.21 KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
9906
0.29
chr5_174673965_174674120 0.21 DRD1
dopamine receptor D1
197169
0.03
chr10_65019032_65019264 0.21 JMJD1C
jumonji domain containing 1C
9678
0.27
chr7_137439335_137439486 0.21 DGKI
diacylglycerol kinase, iota
91872
0.09
chr7_16751263_16751414 0.21 AC073333.8

8185
0.18
chr12_125340893_125341100 0.21 SCARB1
scavenger receptor class B, member 1
7333
0.22
chr20_52352609_52352999 0.21 ENSG00000238468
.
67507
0.12
chr9_98639144_98639295 0.20 ERCC6L2
excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2
1236
0.48
chr2_151338744_151338901 0.20 RND3
Rho family GTPase 3
3074
0.42
chr15_36793558_36793709 0.20 C15orf41
chromosome 15 open reading frame 41
78179
0.12
chr12_62115825_62115976 0.20 FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
105114
0.08
chr1_31459830_31459981 0.20 PUM1
pumilio RNA-binding family member 1
8001
0.17
chr9_80641416_80641906 0.19 GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
3859
0.36
chr6_94127165_94127388 0.19 EPHA7
EPH receptor A7
1968
0.51
chr16_3999501_3999652 0.19 RP11-462G12.1

869
0.56
chr4_140685024_140685175 0.19 ENSG00000252233
.
30488
0.19
chr2_109257559_109258085 0.19 LIMS1
LIM and senescent cell antigen-like domains 1
13446
0.22
chr21_17909068_17909746 0.19 ENSG00000207638
.
2002
0.33
chr2_33682993_33683144 0.19 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
45
0.99
chr1_189407105_189407256 0.19 ENSG00000252553
.
228206
0.02
chr9_35341457_35341792 0.18 AL160274.1
HCG17281; PRO0038; Uncharacterized protein
19638
0.2
chr14_89632118_89632412 0.18 FOXN3
forkhead box N3
14823
0.28
chr1_3087716_3087867 0.18 RP1-163G9.2

37518
0.18
chr4_77491396_77491547 0.18 ENSG00000263445
.
3250
0.21
chr4_170585829_170585980 0.18 CLCN3
chloride channel, voltage-sensitive 3
4691
0.28
chr19_45931964_45932396 0.18 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
288
0.84
chr7_120631344_120631706 0.18 CPED1
cadherin-like and PC-esterase domain containing 1
1849
0.35
chr7_36168506_36168695 0.18 EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
24158
0.18
chr13_114540399_114540680 0.17 GAS6
growth arrest-specific 6
1522
0.45
chr2_192111446_192111930 0.17 MYO1B
myosin IB
679
0.79
chr6_45413846_45414088 0.17 RUNX2
runt-related transcription factor 2
23745
0.2
chr11_46259732_46260224 0.17 CTD-2589M5.4

36120
0.14
chr17_53398574_53398941 0.17 RP11-515O17.2

47743
0.16
chr12_25486836_25487071 0.17 ENSG00000201439
.
70409
0.1
chr8_108316261_108316433 0.17 ANGPT1
angiopoietin 1
32403
0.22
chr6_74434667_74435200 0.17 RP11-553A21.3

29079
0.17
chr12_43136229_43136380 0.17 PRICKLE1
prickle homolog 1 (Drosophila)
152147
0.04
chr3_32602518_32602669 0.17 DYNC1LI1
dynein, cytoplasmic 1, light intermediate chain 1
9152
0.22
chr3_138066783_138067508 0.17 MRAS
muscle RAS oncogene homolog
169
0.96
chr15_64391587_64391738 0.17 SNX1
sorting nexin 1
3437
0.18
chr18_33106392_33106607 0.17 INO80C
INO80 complex subunit C
28544
0.16
chr11_2834821_2835116 0.16 KCNQ1-AS1
KCNQ1 antisense RNA 1
47830
0.11
chr2_227555497_227555648 0.16 ENSG00000263363
.
32063
0.22
chr4_86747653_86747804 0.16 ARHGAP24
Rho GTPase activating protein 24
1170
0.61
chr22_46082903_46083054 0.16 ATXN10
ataxin 10
15299
0.21
chr7_75341548_75341699 0.16 HIP1
huntingtin interacting protein 1
26636
0.18
chr12_131200528_131200853 0.16 RIMBP2
RIMS binding protein 2
136
0.98
chr1_208393211_208393379 0.16 PLXNA2
plexin A2
24370
0.28
chr3_188108011_188108162 0.16 LPP
LIM domain containing preferred translocation partner in lipoma
150434
0.04
chr13_51252397_51252695 0.16 DLEU7-AS1
DLEU7 antisense RNA 1
129446
0.05
chr10_125608306_125608596 0.16 CPXM2
carboxypeptidase X (M14 family), member 2
42879
0.15
chr20_7566360_7566511 0.16 ENSG00000240584
.
48063
0.19
chr9_89738562_89738713 0.16 C9orf170
chromosome 9 open reading frame 170
24922
0.26
chr14_76327643_76327914 0.16 RP11-270M14.4

13737
0.25
chr7_98028694_98029033 0.16 BAIAP2L1
BAI1-associated protein 2-like 1
1517
0.48
chr13_94996950_94997101 0.16 ENSG00000212057
.
120619
0.06
chr19_3818575_3818945 0.16 MATK
megakaryocyte-associated tyrosine kinase
16633
0.11
chr14_63951066_63951267 0.15 ENSG00000252800
.
5176
0.16
chr6_35687700_35688402 0.15 FKBP5
FK506 binding protein 5
8309
0.12
chr10_119132010_119132432 0.15 PDZD8
PDZ domain containing 8
2757
0.3
chr8_107281700_107282399 0.15 OXR1
oxidation resistance 1
424
0.92
chr6_152784305_152784456 0.15 SYNE1
spectrin repeat containing, nuclear envelope 1
9385
0.22
chr19_17790996_17791451 0.15 UNC13A
unc-13 homolog A (C. elegans)
4245
0.17
chr4_146601616_146601767 0.15 C4orf51
chromosome 4 open reading frame 51
214
0.94
chr6_16722645_16722796 0.15 RP1-151F17.1

38649
0.19
chr8_81934177_81934401 0.15 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
90014
0.09
chr6_14639094_14639727 0.15 ENSG00000206960
.
7356
0.34
chr17_67056911_67057062 0.15 ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
61
0.98
chr8_145598687_145598886 0.15 ADCK5
aarF domain containing kinase 5
1036
0.26
chr21_17584209_17584483 0.15 ENSG00000201025
.
72743
0.13
chr3_52039748_52040001 0.15 RPL29
ribosomal protein L29
9916
0.09
chr16_84328151_84329018 0.15 WFDC1
WAP four-disulfide core domain 1
132
0.94
chr4_186488570_186488721 0.14 RP11-301L8.2

20418
0.16
chr1_186834383_186834534 0.14 PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
36336
0.23
chr16_68281342_68281493 0.14 PLA2G15
phospholipase A2, group XV
2122
0.13
chr2_179728640_179728888 0.14 CCDC141
coiled-coil domain containing 141
20914
0.17
chr3_137834054_137834699 0.14 DZIP1L
DAZ interacting zinc finger protein 1-like
75
0.97
chr5_167831410_167831561 0.14 WWC1
WW and C2 domain containing 1
1799
0.45
chr5_36692416_36692567 0.14 CTD-2353F22.1

32784
0.22
chr11_46360410_46360982 0.14 DGKZ
diacylglycerol kinase, zeta
548
0.72
chr6_25179503_25179654 0.14 ENSG00000222373
.
13063
0.19
chr16_19016973_19017124 0.14 ENSG00000207167
.
6431
0.16
chr19_58521610_58521765 0.14 ZNF606
zinc finger protein 606
6970
0.11
chr1_145524889_145525225 0.14 ITGA10
integrin, alpha 10
22
0.95
chr1_217308938_217309289 0.14 ESRRG
estrogen-related receptor gamma
1983
0.51
chr14_92864159_92864342 0.14 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
10473
0.28
chr5_154138190_154138341 0.14 LARP1
La ribonucleoprotein domain family, member 1
1531
0.39
chr14_76620436_76620587 0.13 GPATCH2L
G patch domain containing 2-like
522
0.85
chr13_45009518_45010564 0.13 TSC22D1
TSC22 domain family, member 1
940
0.69
chr5_159208675_159208826 0.13 ADRA1B
adrenoceptor alpha 1B
135040
0.05
chr17_13502555_13502706 0.13 HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
2614
0.37
chr9_100264063_100264279 0.13 TMOD1
tropomodulin 1
250
0.92
chr5_125031921_125032072 0.13 ENSG00000222107
.
345172
0.01
chr4_57974250_57974401 0.13 IGFBP7-AS1
IGFBP7 antisense RNA 1
1603
0.28
chr1_82048437_82048588 0.13 RP5-837I24.2

25125
0.21
chr4_143766947_143768160 0.13 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
99
0.99
chr2_25599883_25600214 0.13 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
34589
0.16
chr10_56993124_56993275 0.13 PCDH15
protocadherin-related 15
86175
0.11
chr2_227665986_227666395 0.13 IRS1
insulin receptor substrate 1
1715
0.35
chr7_115670129_115670280 0.12 TFEC
transcription factor EC
591
0.85
chr12_1626749_1626900 0.12 WNT5B
wingless-type MMTV integration site family, member 5B
12233
0.24
chr2_54195795_54196058 0.12 ACYP2
acylphosphatase 2, muscle type
2049
0.28
chr6_153414041_153414192 0.12 RGS17
regulator of G-protein signaling 17
38268
0.14
chr4_159731146_159731380 0.12 FNIP2
folliculin interacting protein 2
3863
0.25
chrX_105431716_105431867 0.12 MUM1L1
melanoma associated antigen (mutated) 1-like 1
13938
0.29
chr8_38205081_38205318 0.12 RP11-513D5.2

11700
0.13
chr2_134894818_134895366 0.12 ENSG00000263813
.
10396
0.24
chr12_12686379_12686530 0.12 DUSP16
dual specificity phosphatase 16
12395
0.24
chr7_157148744_157148916 0.12 DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
16315
0.23
chr5_44943313_44943551 0.12 MRPS30
mitochondrial ribosomal protein S30
134405
0.05
chr2_203159927_203160078 0.12 ENSG00000238317
.
2230
0.18
chr1_192803524_192803675 0.12 RGS2
regulator of G-protein signaling 2, 24kDa
25428
0.21
chr20_1356402_1356657 0.12 RP11-314N13.3

14263
0.13
chr13_38113810_38113961 0.12 POSTN
periostin, osteoblast specific factor
58978
0.16
chr2_197852125_197852688 0.12 ANKRD44
ankyrin repeat domain 44
12820
0.25
chr10_94039164_94039387 0.11 ENSG00000199881
.
7268
0.17
chr10_6234346_6234592 0.11 RP11-414H17.5

10187
0.15
chr1_115753443_115753594 0.11 RP4-663N10.1

72137
0.11
chr10_126753112_126753370 0.11 ENSG00000264572
.
31802
0.18
chrX_119751985_119752136 0.11 C1GALT1C1
C1GALT1-specific chaperone 1
11790
0.18
chr8_144512945_144513817 0.11 MAFA
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
805
0.48
chr1_230272340_230272635 0.11 GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
69469
0.11
chr7_125333680_125333831 0.11 ENSG00000221418
.
346528
0.01
chr20_19991582_19991882 0.11 NAA20
N(alpha)-acetyltransferase 20, NatB catalytic subunit
6028
0.22
chr5_66935802_66935953 0.11 ENSG00000222939
.
175441
0.03
chr7_90085000_90085151 0.11 CDK14
cyclin-dependent kinase 14
10663
0.23
chr18_57549496_57550010 0.11 PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
17427
0.24
chr5_148796790_148796941 0.11 ENSG00000208035
.
11616
0.13
chr6_129822270_129822588 0.11 RP1-69D17.3

19874
0.26
chr12_90484641_90484914 0.11 ENSG00000252823
.
336941
0.01

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of MEF2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.2 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.1 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0090273 regulation of glucagon secretion(GO:0070092) regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.0 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0051818 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:1901978 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.0 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.0 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.1 GO:1903670 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling