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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for MEIS1

Z-value: 0.99

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Transcription factors associated with MEIS1

Gene Symbol	Gene ID	Gene Info
MEIS1 Ensembl NCBI GeneCards UniProt	ENSG00000143995.15	Meis homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_66800716_66800867	MEIS1	64732	0.132604	0.81	8.3e-03	Click!
chr2_67157367_67157518	MEIS1	421383	0.006713	0.60	9.1e-02	Click!
chr2_66803645_66804000	MEIS1	67763	0.126743	0.56	1.2e-01	Click!
chr2_66735557_66735708	MEIS1	427	0.877982	0.53	1.4e-01	Click!
chr2_66662081_66662232	MEIS1	109	0.946260	-0.51	1.6e-01	Click!

Activity of the MEIS1 motif across conditions

Conditions sorted by the z-value of the MEIS1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_640288_641115	1.10	RAB40C	RAB40C, member RAS oncogene family	369	0.68
chr20_10286915_10287750	0.73	ENSG00000211588	.	55546	0.13
chr8_128919529_128920109	0.73	TMEM75	transmembrane protein 75	40772	0.15
chr9_34651822_34652525	0.70	IL11RA	interleukin 11 receptor, alpha	16	0.94
chr9_96214890_96215815	0.61	FAM120AOS	family with sequence similarity 120A opposite strand	522	0.51
chr17_17726041_17726867	0.59	SREBF1	sterol regulatory element binding transcription factor 1	478	0.73
chr1_14924992_14926197	0.58	KAZN	kazrin, periplakin interacting protein	381	0.93
chr1_78468921_78469158	0.56	RP11-386I14.4		1199	0.35
chr20_22384501_22385014	0.54	FOXA2	forkhead box A2	180344	0.03
chr4_157692811_157693135	0.53	RP11-154F14.2		69538	0.11
chr5_37736234_37736424	0.53	ENSG00000206743	.	35790	0.19
chr21_35678304_35678597	0.51	ENSG00000266007	.	1020	0.57
chr1_26704591_26705236	0.51	ZNF683	zinc finger protein 683	3900	0.15
chr9_109459969_109460612	0.49	ENSG00000200131	.	18032	0.28
chr5_134727497_134727842	0.48	H2AFY	H2A histone family, member Y	7232	0.17
chr19_5802056_5802207	0.48	DUS3L	dihydrouridine synthase 3-like (S. cerevisiae)	10882	0.09
chr5_171380881_171381289	0.48	FBXW11	F-box and WD repeat domain containing 11	23675	0.23
chr2_84282857_84283143	0.47	ENSG00000252298	.	197053	0.03
chr8_42063953_42065062	0.47	PLAT	plasminogen activator, tissue	576	0.71
chr1_172360185_172360576	0.47	DNM3	dynamin 3	12222	0.16
chr16_87469465_87469755	0.47	ZCCHC14	zinc finger, CCHC domain containing 14	2870	0.22
chr20_55204347_55205219	0.47	TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	425	0.81
chr9_113342240_113342458	0.46	SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	189	0.96
chr19_19174720_19175940	0.45	SLC25A42	solute carrier family 25, member 42	522	0.7
chr1_68149030_68149645	0.45	GADD45A	growth arrest and DNA-damage-inducible, alpha	1407	0.47
chr9_14180845_14181011	0.44	NFIB	nuclear factor I/B	131	0.98
chr5_167266384_167266535	0.44	ENSG00000221741	.	31211	0.18
chr20_16514306_16514457	0.44	KIF16B	kinesin family member 16B	39697	0.2
chr13_30251628_30251779	0.44	SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	81878	0.11
chr13_56670560_56670711	0.44	ENSG00000238455	.	463123	0.01
chr5_1315874_1316496	0.44	ENSG00000263670	.	6693	0.18
chr18_54318050_54319471	0.43	TXNL1	thioredoxin-like 1	64	0.61
chr12_66122461_66123138	0.43	HMGA2	high mobility group AT-hook 2	95112	0.08
chr19_13107353_13108160	0.43	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	1104	0.3
chr11_10695962_10696877	0.43	MRVI1	murine retrovirus integration site 1 homolog	18642	0.17
chr1_183156151_183156302	0.43	LAMC2	laminin, gamma 2	803	0.7
chrX_73755392_73756724	0.42	SLC16A2	solute carrier family 16, member 2 (thyroid hormone transporter)	15103	0.23
chr1_210465594_210466382	0.42	HHAT	hedgehog acyltransferase	35608	0.17
chr15_48010788_48011252	0.42	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	334	0.93
chr19_54676940_54677234	0.42	TMC4	transmembrane channel-like 4	143	0.89
chr1_161195725_161196723	0.42	TOMM40L	translocase of outer mitochondrial membrane 40 homolog (yeast)-like	130	0.84
chr17_46129068_46130070	0.41	NFE2L1	nuclear factor, erythroid 2-like 1	2121	0.15
chr6_13761461_13761614	0.41	MCUR1	mitochondrial calcium uniporter regulator 1	40040	0.15
chr9_86916681_86916945	0.41	RP11-380F14.2		23679	0.22
chr10_72163983_72165283	0.40	EIF4EBP2	eukaryotic translation initiation factor 4E binding protein 2	498	0.77
chr13_35962874_35963128	0.40	MAB21L1	mab-21-like 1 (C. elegans)	87831	0.09
chr5_95294796_95295032	0.40	ELL2	elongation factor, RNA polymerase II, 2	2638	0.26
chr7_33972032_33972255	0.40	BMPER	BMP binding endothelial regulator	26998	0.26
chr2_145732023_145732174	0.39	ENSG00000253036	.	360540	0.01
chr3_132349108_132349259	0.39	UBA5	ubiquitin-like modifier activating enzyme 5	24107	0.16
chr22_43042721_43042986	0.39	CYB5R3	cytochrome b5 reductase 3	113	0.95
chr7_32110576_32110834	0.39	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	231	0.97
chr1_50489142_50489611	0.39	AGBL4	ATP/GTP binding protein-like 4	196	0.94
chr6_72129322_72130506	0.39	ENSG00000207827	.	16590	0.22
chr6_71108128_71108412	0.38	FAM135A	family with sequence similarity 135, member A	14741	0.21
chr1_200749440_200749639	0.38	CAMSAP2	calmodulin regulated spectrin-associated protein family, member 2	40632	0.17
chr1_239302822_239302973	0.38	CHRM3	cholinergic receptor, muscarinic 3	489476	0.01
chr15_95739591_95739742	0.38	ENSG00000222076	.	549367	0.0
chr1_151174318_151174695	0.38	PIP5K1A	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	3455	0.12
chr3_192535250_192535401	0.38	FGF12	fibroblast growth factor 12	49772	0.16
chr21_32715523_32716836	0.38	TIAM1	T-cell lymphoma invasion and metastasis 1	415	0.91
chr16_75121726_75121965	0.37	ZNRF1	zinc and ring finger 1, E3 ubiquitin protein ligase	16837	0.15
chr11_7599067_7599755	0.37	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	1140	0.49
chr2_24123591_24123937	0.37	ATAD2B	ATPase family, AAA domain containing 2B	26171	0.17
chr6_91500118_91500269	0.37	MAP3K7	mitogen-activated protein kinase kinase kinase 7	203429	0.03
chr14_105436556_105437076	0.37	AHNAK2	AHNAK nucleoprotein 2	7878	0.16
chr18_30049396_30050442	0.37	GAREM	GRB2 associated, regulator of MAPK1	476	0.87
chr7_33946724_33946875	0.37	BMPER	BMP binding endothelial regulator	1654	0.54
chr18_24736144_24736295	0.36	CHST9	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9	13217	0.31
chr12_95509986_95510137	0.36	FGD6	FYVE, RhoGEF and PH domain containing 6	688	0.74
chr9_110250307_110251795	0.36	KLF4	Kruppel-like factor 4 (gut)	360	0.89
chr15_82185842_82186054	0.36	ENSG00000222521	.	150687	0.04
chr6_106982104_106982255	0.36	AIM1	absent in melanoma 1	6830	0.22
chr2_29337699_29338221	0.36	CLIP4	CAP-GLY domain containing linker protein family, member 4	332	0.87
chr3_172303826_172303977	0.36	AC007919.2	HCG1787166; PRO1163; Uncharacterized protein	57582	0.11
chr15_47476270_47477144	0.36	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	409	0.87
chr12_67807670_67807821	0.36	CAND1	cullin-associated and neddylation-dissociated 1	114993	0.07
chr22_30658388_30658630	0.36	OSM	oncostatin M	3298	0.13
chr2_43822335_43823890	0.35	THADA	thyroid adenoma associated	1	0.98
chr20_39945349_39946123	0.35	ZHX3	zinc fingers and homeoboxes 3	90	0.97
chr12_15600082_15600233	0.35	RERG	RAS-like, estrogen-regulated, growth inhibitor	98625	0.08
chr7_124430606_124430965	0.35	GPR37	G protein-coupled receptor 37 (endothelin receptor type B-like)	25104	0.22
chr13_60580593_60580744	0.35	DIAPH3-AS1	DIAPH3 antisense RNA 1	6217	0.26
chr1_115153328_115153616	0.35	BCAS2	breast carcinoma amplified sequence 2	29212	0.16
chr12_69418432_69418757	0.35	CPM	carboxypeptidase M	61545	0.11
chr11_8832812_8833111	0.35	ST5	suppression of tumorigenicity 5	73	0.96
chr14_21081225_21081433	0.35	RNASE11	ribonuclease, RNase A family, 11 (non-active)	3286	0.14
chr17_78866297_78866787	0.34	RPTOR	regulatory associated protein of MTOR, complex 1	29982	0.14
chr12_59472769_59472920	0.34	RP11-150C16.1		158424	0.04
chr16_49150769_49150920	0.34	CBLN1	cerebellin 1 precursor	164629	0.04
chr20_15793445_15793596	0.34	MACROD2	MACRO domain containing 2	49930	0.19
chr6_33610158_33610417	0.34	ITPR3	inositol 1,4,5-trisphosphate receptor, type 3	21126	0.13
chr17_38178315_38178466	0.34	MED24	mediator complex subunit 24	1023	0.38
chr14_45559377_45559745	0.34	ENSG00000212615	.	2115	0.2
chr13_33791465_33791616	0.34	STARD13	StAR-related lipid transfer (START) domain containing 13	11397	0.23
chr6_36645350_36645501	0.34	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	163	0.94
chr12_54391177_54391923	0.34	HOXC-AS2	HOXC cluster antisense RNA 2	981	0.22
chr10_104069935_104070086	0.34	ENSG00000251989	.	49023	0.09
chr11_120271300_120271503	0.33	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	15398	0.2
chr2_29548877_29549028	0.33	ALK	anaplastic lymphoma receptor tyrosine kinase	102692	0.07
chr9_73095232_73095769	0.33	KLF9	Kruppel-like factor 9	65960	0.12
chr3_79432526_79432918	0.33	ENSG00000265193	.	124315	0.06
chr1_66998527_66999432	0.33	SGIP1	SH3-domain GRB2-like (endophilin) interacting protein 1	87	0.98
chr9_102021888_102022109	0.33	ENSG00000222337	.	24306	0.17
chr7_30189174_30189325	0.33	MTURN	maturin, neural progenitor differentiation regulator homolog (Xenopus)	3736	0.2
chr12_58704955_58705136	0.33	RP11-362K2.2	Protein LOC100506869	232862	0.02
chr12_1423709_1423860	0.33	RP5-951N9.2		71215	0.1
chr4_107956832_107957922	0.32	DKK2	dickkopf WNT signaling pathway inhibitor 2	77	0.99
chr13_99641281_99641432	0.32	DOCK9	dedicator of cytokinesis 9	11018	0.23
chr5_157861845_157861996	0.32	ENSG00000222626	.	457956	0.01
chr6_44195015_44195399	0.32	SLC29A1	solute carrier family 29 (equilibrative nucleoside transporter), member 1	331	0.82
chr1_32421860_32422231	0.32	PTP4A2	protein tyrosine phosphatase type IVA, member 2	13868	0.17
chr4_181055224_181055668	0.32	NA	NA	> 10⁶	NA
chr1_33168933_33169118	0.32	SYNC	syncoilin, intermediate filament protein	172	0.93
chr3_133524639_133525577	0.32	SRPRB	signal recognition particle receptor, B subunit	649	0.75
chr1_90184902_90185053	0.32	ENSG00000239176	.	48900	0.13
chr15_67390777_67391884	0.32	SMAD3	SMAD family member 3	313	0.93
chr17_33391542_33391948	0.32	RFFL	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	874	0.45
chr17_45198216_45198367	0.32	ENSG00000221016	.	2423	0.23
chr2_198464213_198464591	0.32	RFTN2	raftlin family member 2	18217	0.19
chr4_47851555_47851706	0.32	CORIN	corin, serine peptidase	11507	0.21
chr1_158087708_158088406	0.32	KIRREL	kin of IRRE like (Drosophila)	31587	0.18
chr10_77168132_77169350	0.32	ENSG00000237149	.	5929	0.2
chr6_19838575_19839711	0.32	RP1-167F1.2		168	0.95
chr7_132260669_132261651	0.32	PLXNA4	plexin A4	69	0.98
chr13_105442959_105443110	0.32	DAOA	D-amino acid oxidase activator	675558	0.0
chr4_125725281_125725432	0.32	ANKRD50	ankyrin repeat domain 50	91469	0.1
chr17_64464860_64465690	0.32	RP11-4F22.2		52303	0.15
chr2_17994561_17995135	0.32	MSGN1	mesogenin 1	2915	0.27
chr6_75634606_75634757	0.31	COL12A1	collagen, type XII, alpha 1	194093	0.03
chr10_46010179_46010570	0.31	MARCH8	membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase	20445	0.22
chr1_209393485_209393990	0.31	ENSG00000230937	.	211741	0.02
chr7_67474743_67474894	0.31	ENSG00000265600	.	653151	0.0
chr10_112113893_112114201	0.31	SMNDC1	survival motor neuron domain containing 1	49338	0.14
chr14_102050713_102051023	0.31	DIO3	deiodinase, iodothyronine, type III	23180	0.17
chr7_129598360_129598651	0.31	ENSG00000207184	.	3411	0.15
chr10_103326247_103326406	0.31	DPCD	deleted in primary ciliary dyskinesia homolog (mouse)	4080	0.2
chr7_26126830_26127131	0.31	ENSG00000266430	.	27021	0.2
chr2_169377724_169378182	0.31	ENSG00000265694	.	61500	0.1
chr7_115912354_115912783	0.31	TES	testis derived transcript (3 LIM domains)	22079	0.19
chr17_37183284_37183583	0.31	LRRC37A11P	leucine rich repeat containing 37, member A11, pseudogene	97	0.96
chr3_9745623_9746706	0.31	CPNE9	copine family member IX	654	0.62
chr6_166795582_166796398	0.31	MPC1	mitochondrial pyruvate carrier 1	496	0.56
chr1_27443108_27443302	0.31	SLC9A1	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	37768	0.14
chr1_44030641_44030792	0.31	PTPRF	protein tyrosine phosphatase, receptor type, F	19969	0.18
chr2_174000750_174001454	0.31	MLTK	Mitogen-activated protein kinase kinase kinase MLT	45755	0.16
chr21_30502885_30503196	0.31	MAP3K7CL	MAP3K7 C-terminal like	81	0.96
chr16_14398873_14399280	0.31	ENSG00000207639	.	1252	0.44
chr12_102040565_102040734	0.31	RP11-755O11.2		4077	0.2
chr20_5712743_5712894	0.31	C20orf196	chromosome 20 open reading frame 196	18221	0.25
chr1_165602062_165602213	0.31	MGST3	microsomal glutathione S-transferase 3	660	0.71
chr12_19270446_19270597	0.31	PLEKHA5	pleckstrin homology domain containing, family A member 5	12127	0.23
chr2_237551540_237552008	0.30	ACKR3	atypical chemokine receptor 3	73490	0.12
chr9_139886935_139887950	0.30	C9orf142	chromosome 9 open reading frame 142	572	0.45
chr2_102359188_102359339	0.30	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	44271	0.19
chr15_72529055_72529849	0.30	PKM	pyruvate kinase, muscle	5288	0.17
chr5_124202427_124202671	0.30	ZNF608	zinc finger protein 608	118049	0.05
chr1_9653728_9653879	0.30	TMEM201	transmembrane protein 201	3152	0.26
chr7_148232370_148232768	0.30	C7orf33	chromosome 7 open reading frame 33	55088	0.14
chr10_76249005_76249156	0.30	RP11-46O21.2		39996	0.19
chr5_58830530_58830681	0.30	PDE4D	phosphodiesterase 4D, cAMP-specific	51614	0.19
chr10_123357016_123357770	0.30	FGFR2	fibroblast growth factor receptor 2	205	0.97
chr2_218560010_218560412	0.30	DIRC3	disrupted in renal carcinoma 3	61067	0.14
chr1_31407482_31407633	0.30	ENSG00000200154	.	1063	0.44
chr1_19973947_19974889	0.30	NBL1	neuroblastoma 1, DAN family BMP antagonist	314	0.87
chr7_48125773_48125924	0.30	UPP1	uridine phosphorylase 1	2377	0.33
chr18_29030114_29030410	0.30	DSG3	desmoglein 3	2504	0.25
chr9_90588787_90589959	0.30	CDK20	cyclin-dependent kinase 20	29	0.98
chr13_114559546_114559768	0.30	GAS6	growth arrest-specific 6	7383	0.25
chr2_28939308_28939670	0.30	AC097724.3		19486	0.15
chr5_57134719_57134870	0.30	ENSG00000266864	.	34079	0.24
chr20_19915434_19915955	0.30	RIN2	Ras and Rab interactor 2	45484	0.16
chr3_112964540_112964768	0.30	BOC	BOC cell adhesion associated, oncogene regulated	29456	0.19
chr6_86113057_86113246	0.30	NT5E	5'-nucleotidase, ecto (CD73)	46658	0.19
chr10_35060387_35060538	0.30	PARD3	par-3 family cell polarity regulator	43787	0.16
chr6_67228735_67228886	0.30	ENSG00000221281	.	159492	0.04
chr14_85707273_85707789	0.30	ENSG00000252529	.	30745	0.26
chr13_24782165_24782389	0.29	SPATA13	spermatogenesis associated 13	43555	0.13
chr9_18689231_18689382	0.29	ENSG00000252960	.	38161	0.2
chr17_29020953_29021202	0.29	ENSG00000241631	.	8716	0.17
chr4_57974006_57974157	0.29	ENSG00000238541	.	1570	0.29
chr22_46462951_46463814	0.29	RP6-109B7.4		2389	0.16
chr18_46460407_46461027	0.29	SMAD7	SMAD family member 7	14158	0.24
chr3_184037306_184037783	0.29	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	1	0.95
chr2_182760406_182760853	0.29	SSFA2	sperm specific antigen 2	3706	0.25
chr14_37570606_37570757	0.29	RP11-537P22.2		2913	0.31
chr17_72008631_72008782	0.29	RPL38	ribosomal protein L38	191015	0.02
chr1_214397865_214398571	0.29	SMYD2	SET and MYND domain containing 2	56358	0.16
chr17_74442541_74443075	0.29	UBE2O	ubiquitin-conjugating enzyme E2O	6480	0.12
chr13_107540716_107540867	0.29	ENSG00000239050	.	86583	0.11
chr1_113933852_113934516	0.29	MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	573	0.86
chr10_115860454_115861476	0.29	ENSG00000253066	.	10208	0.2
chr8_144099091_144099248	0.29	LY6E	lymphocyte antigen 6 complex, locus E	230	0.93
chr6_158090942_158091198	0.29	ZDHHC14	zinc finger, DHHC-type containing 14	77029	0.1
chr2_70994239_70995345	0.29	ADD2	adducin 2 (beta)	55	0.97
chr13_114527173_114527324	0.29	GAS6-AS1	GAS6 antisense RNA 1	8645	0.21
chr9_112839583_112839734	0.29	AKAP2	A kinase (PRKA) anchor protein 2	12819	0.28
chr2_153211288_153211531	0.29	FMNL2	formin-like 2	19658	0.26
chr7_36566798_36566949	0.29	AC006960.7		64241	0.1
chr3_186335083_186335441	0.29	AHSG	alpha-2-HS-glycoprotein	4407	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MEIS1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.3	0.5	GO:0035844	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.2	0.7	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2	0.9	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.7	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.2	0.4	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.2	0.2	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.2	0.3	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.2	1.3	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2	0.2	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.6	GO:0060013	righting reflex(GO:0060013)
0.1	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	0.4	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	1.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.1	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.5	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1	0.4	GO:0003181	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.1	0.4	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.3	GO:0072081	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.1	0.3	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1	0.3	GO:0060426	lung vasculature development(GO:0060426)
0.1	0.3	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.1	GO:0060435	bronchiole development(GO:0060435)
0.1	1.0	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	0.1	GO:0051280	negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1	0.3	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	0.4	GO:0008218	bioluminescence(GO:0008218)
0.1	1.3	GO:0035329	hippo signaling(GO:0035329)
0.1	0.3	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.1	0.4	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.1	0.7	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1	0.5	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.3	GO:0009732	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.3	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1	0.1	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.1	0.3	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.2	GO:0060157	urinary bladder development(GO:0060157)
0.1	0.3	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.3	GO:0042482	positive regulation of odontogenesis(GO:0042482) positive regulation of tooth mineralization(GO:0070172)
0.1	0.3	GO:0060174	limb bud formation(GO:0060174)
0.1	0.5	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.1	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.1	0.4	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1	0.1	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.1	0.4	GO:0070141	response to UV-A(GO:0070141)
0.1	0.2	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.1	0.3	GO:0010193	response to ozone(GO:0010193)
0.1	0.5	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.1	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.1	0.3	GO:0015816	glycine transport(GO:0015816)
0.1	0.3	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.3	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.1	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.1	0.4	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.2	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.2	GO:0051451	myoblast migration(GO:0051451)
0.1	0.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.2	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.5	GO:0051934	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.1	0.1	GO:0070100	regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1	0.2	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.1	GO:0098810	neurotransmitter reuptake(GO:0098810)
0.1	0.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.1	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.1	0.3	GO:0048242	epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.1	0.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	0.4	GO:1902667	regulation of axon guidance(GO:1902667)
0.1	0.4	GO:0060037	pharyngeal system development(GO:0060037)
0.1	0.1	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.3	GO:0051014	actin filament severing(GO:0051014)
0.1	0.1	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.1	0.2	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1	0.4	GO:0042640	anagen(GO:0042640)
0.1	0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.1	0.3	GO:0032933	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1	0.2	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	0.2	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1	0.1	GO:0006991	response to sterol depletion(GO:0006991)
0.1	0.2	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1	0.2	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.1	0.1	GO:0060685	regulation of prostatic bud formation(GO:0060685)
0.1	0.2	GO:0070307	lens fiber cell development(GO:0070307)
0.1	0.2	GO:0070295	renal water absorption(GO:0070295)
0.1	0.4	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.1	GO:0045683	negative regulation of epidermis development(GO:0045683)
0.1	0.1	GO:0003197	endocardial cushion development(GO:0003197)
0.1	0.2	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	0.2	GO:0021978	telencephalon regionalization(GO:0021978)
0.1	0.2	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1	0.5	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.2	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.1	GO:0090030	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347) regulation of steroid hormone biosynthetic process(GO:0090030)
0.1	1.0	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	0.2	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1	0.1	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.1	0.3	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	0.2	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.1	0.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.2	GO:0090400	stress-induced premature senescence(GO:0090400)
0.1	0.3	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.1	GO:0060438	trachea development(GO:0060438)
0.1	0.2	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.1	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.1	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1	0.3	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
0.1	0.2	GO:0048865	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.1	0.1	GO:0032203	telomere formation via telomerase(GO:0032203)
0.1	0.3	GO:0033194	response to hydroperoxide(GO:0033194)
0.1	0.1	GO:0021569	rhombomere 3 development(GO:0021569)
0.1	0.3	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.1	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1	0.9	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	0.2	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.8	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.1	0.2	GO:0021570	rhombomere 4 development(GO:0021570)
0.1	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.1	0.1	GO:0033088	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.1	GO:2000737	negative regulation of stem cell differentiation(GO:2000737)
0.1	0.3	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.0	GO:0060437	lung growth(GO:0060437)
0.0	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.0	GO:0007442	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0021546	rhombomere development(GO:0021546)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.2	GO:0050746	regulation of lipoprotein metabolic process(GO:0050746)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.0	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.2	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0048840	otolith development(GO:0048840)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.2	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.2	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	4.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.8	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.3	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.0	0.1	GO:0060044	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.6	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0090037	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.2	GO:0035247	peptidyl-arginine omega-N-methylation(GO:0035247)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.4	GO:0007398	ectoderm development(GO:0007398)
0.0	0.3	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	0.1	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.3	GO:0031649	heat generation(GO:0031649)
0.0	0.8	GO:0046068	cGMP metabolic process(GO:0046068)
0.0	0.3	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.0	GO:0060850	regulation of transcription involved in cell fate commitment(GO:0060850)
0.0	0.2	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.3	GO:0043113	receptor clustering(GO:0043113)
0.0	0.0	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166) adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.2	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.0	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.2	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.1	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.2	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.2	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.0	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.1	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.5	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.2	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.2	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.0	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.0	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	0.2	GO:0006547	histidine metabolic process(GO:0006547)
0.0	0.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.1	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.1	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:1901655	cellular response to ketone(GO:1901655)
0.0	0.0	GO:0060068	vagina development(GO:0060068)
0.0	0.1	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.9	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.0	GO:0060065	uterus development(GO:0060065) cornea development in camera-type eye(GO:0061303)
0.0	0.1	GO:0010656	negative regulation of muscle cell apoptotic process(GO:0010656)
0.0	0.1	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0	0.3	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.1	GO:0006273	lagging strand elongation(GO:0006273)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.4	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.1	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.1	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.0	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.0	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.1	GO:0032610	interleukin-1 alpha production(GO:0032610)
0.0	0.0	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.0	GO:0045616	regulation of keratinocyte differentiation(GO:0045616)
0.0	0.1	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.3	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.0	0.1	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.0	0.0	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.0	0.1	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.9	GO:0031424	keratinization(GO:0031424)
0.0	0.1	GO:0046541	saliva secretion(GO:0046541)
0.0	0.1	GO:0030539	male genitalia development(GO:0030539)
0.0	0.0	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.0	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0072210	metanephric nephron development(GO:0072210)
0.0	0.1	GO:0046184	aldehyde biosynthetic process(GO:0046184)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.0	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.3	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.2	GO:0009267	cellular response to starvation(GO:0009267)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.0	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.1	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.0	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.1	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.0	GO:0048486	parasympathetic nervous system development(GO:0048486)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.0	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:1901862	negative regulation of muscle tissue development(GO:1901862)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.2	GO:0032459	regulation of protein oligomerization(GO:0032459)
0.0	0.1	GO:0071384	cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0	0.1	GO:0002857	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.4	GO:0048675	axon extension(GO:0048675) neuron projection extension(GO:1990138)
0.0	0.0	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.1	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.0	GO:0060676	ureteric bud formation(GO:0060676)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.2	GO:0048485	sympathetic nervous system development(GO:0048485)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.2	GO:0050771	negative regulation of axonogenesis(GO:0050771)
0.0	0.2	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.0	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.0	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.0	GO:0003071	renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071)
0.0	0.0	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.0	GO:0071503	response to heparin(GO:0071503)
0.0	0.2	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0	0.1	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	0.1	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.0	GO:0019731	antibacterial humoral response(GO:0019731)
0.0	0.0	GO:0019614	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.0	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.1	GO:0010771	negative regulation of cell morphogenesis involved in differentiation(GO:0010771)
0.0	0.1	GO:0055010	ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.0	0.0	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.0	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0	0.1	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.1	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.0	GO:0002604	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.0	0.0	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0001676	long-chain fatty acid metabolic process(GO:0001676)
0.0	0.1	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0048318	axial mesoderm development(GO:0048318)
0.0	0.2	GO:0015697	quaternary ammonium group transport(GO:0015697)
0.0	0.0	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.3	GO:0044243	collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0	0.1	GO:0032740	positive regulation of interleukin-17 production(GO:0032740)
0.0	0.1	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.1	GO:0007350	blastoderm segmentation(GO:0007350)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.2	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.0	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.0	0.0	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.0	GO:1903960	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.0	GO:0032069	regulation of nuclease activity(GO:0032069)
0.0	0.0	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0001502	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.0	GO:0034766	negative regulation of ion transmembrane transport(GO:0034766) negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0	0.0	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.0	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.0	GO:0048333	mesodermal cell fate commitment(GO:0001710) mesodermal cell differentiation(GO:0048333)
0.0	0.2	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.0	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.3	GO:0007588	excretion(GO:0007588)
0.0	0.0	GO:0052803	imidazole-containing compound metabolic process(GO:0052803)
0.0	0.0	GO:0021591	ventricular system development(GO:0021591)
0.0	0.1	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0	0.0	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.0	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0043260	laminin-11 complex(GO:0043260)
0.1	0.9	GO:0043256	laminin complex(GO:0043256)
0.1	2.2	GO:0030057	desmosome(GO:0030057)
0.1	0.4	GO:0043218	compact myelin(GO:0043218)
0.1	0.3	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.4	GO:0005915	zonula adherens(GO:0005915)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.2	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	0.6	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.2	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.5	GO:0031941	filamentous actin(GO:0031941)
0.1	0.4	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.7	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.4	GO:0043034	costamere(GO:0043034)
0.0	0.6	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	1.4	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	6.2	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.3	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.2	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.1	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	1.7	GO:0005911	cell-cell junction(GO:0005911)
0.0	1.4	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.0	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	1.1	GO:0030426	growth cone(GO:0030426)
0.0	0.9	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.1	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.4	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0046930	pore complex(GO:0046930)
0.0	1.2	GO:0001726	ruffle(GO:0001726)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.2	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.2	GO:0001533	cornified envelope(GO:0001533)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0044447	axoneme part(GO:0044447)
0.0	0.0	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.3	GO:0031526	brush border membrane(GO:0031526)
0.0	0.2	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.0	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0000801	central element(GO:0000801)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	0.6	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.2	0.7	GO:0048495	Roundabout binding(GO:0048495)
0.2	0.5	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	1.2	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.2	0.7	GO:0045499	chemorepellent activity(GO:0045499)
0.2	0.8	GO:0017154	semaphorin receptor activity(GO:0017154)
0.2	0.8	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.2	0.5	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	0.6	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.5	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.5	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.6	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.4	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.9	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.3	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	1.3	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	0.5	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.2	GO:0070052	collagen V binding(GO:0070052)
0.1	0.5	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1	0.2	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	0.5	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.3	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.4	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.1	0.4	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.4	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.1	0.2	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.3	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.2	GO:0030172	troponin C binding(GO:0030172)
0.1	0.2	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.7	GO:0008430	selenium binding(GO:0008430)
0.1	0.6	GO:0048019	receptor antagonist activity(GO:0048019)
0.1	0.2	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.1	0.2	GO:0005113	patched binding(GO:0005113)
0.1	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.2	GO:0008517	folic acid transporter activity(GO:0008517)
0.1	0.2	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.1	0.2	GO:0001601	peptide YY receptor activity(GO:0001601)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.5	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	1.0	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.3	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.1	0.2	GO:0051380	norepinephrine binding(GO:0051380)
0.1	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.2	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.3	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.2	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.8	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.2	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.3	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.3	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.4	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.6	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.2	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.4	GO:0043394	proteoglycan binding(GO:0043394)
0.0	0.4	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.2	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	1.1	GO:0005518	collagen binding(GO:0005518)
0.0	1.0	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.4	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.2	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.2	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.3	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.2	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.2	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	1.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.3	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.2	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.6	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	1.4	GO:0008201	heparin binding(GO:0008201)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.6	GO:0004601	peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.6	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.0	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.3	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.1	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0015421	oligopeptide-transporting ATPase activity(GO:0015421)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.3	GO:0019209	kinase activator activity(GO:0019209)
0.0	0.0	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	4.2	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.0	GO:0019798	procollagen-proline dioxygenase activity(GO:0019798)
0.0	0.0	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.0	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.0	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.0	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.0	GO:0080030	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	1.1	GO:0008083	growth factor activity(GO:0008083)
0.0	0.0	GO:0070061	fructose binding(GO:0070061)
0.0	0.1	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.0	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.5	GO:0005178	integrin binding(GO:0005178)
0.0	0.0	GO:0051183	vitamin transporter activity(GO:0051183)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	1.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.7	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.2	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	1.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	1.6	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.6	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	1.8	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	5.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.5	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.4	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.5	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.9	PID FGF PATHWAY	FGF signaling pathway
0.0	0.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.7	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.0	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	4.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	1.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.3	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.1	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.0	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.4	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.1	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	1.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	2.2	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.4	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.6	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.3	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	1.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.4	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.0	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.0	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.0	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.1	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.0	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.0	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.1	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.0	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.1	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.0	0.0	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.1	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly

Results for MEIS1

Z-value: 0.99

Motif logo

Transcription factors associated with MEIS1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the MEIS1 motif across conditions

Conditions sorted by the z-value of the MEIS1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MEIS1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: