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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for MESP1

Z-value: 1.18

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Transcription factors associated with MESP1

Gene Symbol	Gene ID	Gene Info
MESP1 Ensembl NCBI GeneCards UniProt	ENSG00000166823.5	mesoderm posterior bHLH transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr15_90283484_90283688	MESP1	10955	0.109694	-0.38	3.1e-01	Click!
chr15_90294233_90294789	MESP1	30	0.961388	0.35	3.6e-01	Click!
chr15_90293549_90294164	MESP1	685	0.566331	0.08	8.3e-01	Click!

Activity of the MESP1 motif across conditions

Conditions sorted by the z-value of the MESP1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_129323468_129324020	1.50	PLXND1	plexin D1	1917	0.3
chr19_57182553_57183430	0.83	ZNF835	zinc finger protein 835	137	0.95
chr9_97401149_97402104	0.58	FBP1	fructose-1,6-bisphosphatase 1	163	0.96
chr19_16436739_16437476	0.57	KLF2	Kruppel-like factor 2	1456	0.3
chr11_63639243_63639445	0.48	MARK2	MAP/microtubule affinity-regulating kinase 2	2596	0.2
chr9_140500205_140501463	0.46	ARRDC1	arrestin domain containing 1	679	0.56
chr22_37310592_37310811	0.43	CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	1026	0.44
chr7_73443076_73443679	0.40	ELN	elastin	859	0.62
chr5_175665017_175665241	0.38	SIMC1	SUMO-interacting motifs containing 1	236	0.94
chr10_15391105_15391301	0.37	FAM171A1	family with sequence similarity 171, member A1	21855	0.25
chr19_14550010_14550416	0.35	PKN1	protein kinase N1	859	0.46
chr11_72539440_72539591	0.33	ATG16L2	autophagy related 16-like 2 (S. cerevisiae)	5987	0.14
chr21_46326285_46326436	0.33	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	4185	0.13
chr6_6007915_6008396	0.33	NRN1	neuritin 1	955	0.65
chr19_4872699_4872850	0.32	ENSG00000264899	.	3950	0.13
chr1_3566019_3566622	0.32	WRAP73	WD repeat containing, antisense to TP73	270	0.85
chr7_45959503_45959698	0.31	IGFBP3	insulin-like growth factor binding protein 3	1250	0.48
chr2_227835215_227835366	0.31	ENSG00000212391	.	1452	0.52
chr20_60813797_60814657	0.30	OSBPL2	oxysterol binding protein-like 2	647	0.65
chr2_232531790_232531942	0.30	ENSG00000239202	.	20882	0.15
chr19_18770811_18771071	0.30	KLHL26	kelch-like family member 26	23074	0.1
chr19_14486645_14486802	0.30	CD97	CD97 molecule	5245	0.16
chr5_98362367_98362646	0.29	ENSG00000200351	.	90055	0.09
chr7_135432763_135432935	0.29	FAM180A	family with sequence similarity 180, member A	611	0.71
chr10_26728445_26728931	0.29	APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	1334	0.57
chrY_21146527_21146678	0.29	ENSG00000252766	.	34371	0.23
chr17_48281818_48281998	0.29	COL1A1	collagen, type I, alpha 1	2915	0.16
chr11_1784168_1785131	0.29	AC068580.5		330	0.47
chr19_4084114_4084300	0.29	MAP2K2	mitogen-activated protein kinase kinase 2	16838	0.1
chr11_308095_309459	0.28	IFITM2	interferon induced transmembrane protein 2	369	0.66
chr1_246948051_246948632	0.28	ENSG00000227953	.	5585	0.17
chr16_87298255_87298406	0.28	RP11-178L8.5		27314	0.12
chr2_241504790_241504976	0.28	RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1	338	0.81
chr10_135073626_135073923	0.28	MIR202HG	MIR202 host gene (non-protein coding)	12379	0.1
chr19_17983159_17983879	0.26	SLC5A5	solute carrier family 5 (sodium/iodide cotransporter), member 5	737	0.53
chr22_50963015_50963954	0.26	SCO2	SCO2 cytochrome c oxidase assembly protein	549	0.44
chr10_13313411_13313562	0.26	PHYH	phytanoyl-CoA 2-hydroxylase	28063	0.14
chr8_133772520_133773234	0.26	TMEM71	transmembrane protein 71	1	0.98
chr21_22548352_22548537	0.26	NCAM2	neural cell adhesion molecule 2	29006	0.23
chr6_34283894_34284092	0.25	C6orf1	chromosome 6 open reading frame 1	66746	0.09
chr17_79981151_79982026	0.25	LRRC45	leucine rich repeat containing 45	210	0.63
chr19_43028303_43028515	0.25	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	3565	0.21
chr9_94441418_94441569	0.25	ENSG00000266855	.	42960	0.21
chr19_47218817_47220203	0.25	PRKD2	protein kinase D2	343	0.75
chr6_27636501_27636652	0.25	ENSG00000238648	.	37388	0.14
chr14_105527312_105527781	0.25	GPR132	G protein-coupled receptor 132	3727	0.23
chr4_77659160_77659311	0.25	RP11-359D14.2		20392	0.2
chr18_74075855_74076006	0.24	RP11-504I13.3		8742	0.23
chr6_39760623_39760848	0.24	DAAM2	dishevelled associated activator of morphogenesis 2	59	0.98
chr2_37844682_37844833	0.24	AC006369.2		17478	0.22
chr10_101767094_101767245	0.24	DNMBP	dynamin binding protein	2507	0.28
chr14_39592310_39592461	0.24	GEMIN2	gem (nuclear organelle) associated protein 2	8850	0.18
chr17_47694059_47694247	0.24	SPOP	speckle-type POZ protein	29831	0.11
chr19_18451078_18452116	0.24	PGPEP1	pyroglutamyl-peptidase I	148	0.91
chr22_41417818_41418675	0.24	ENSG00000222698	.	23255	0.13
chr1_192921022_192921264	0.24	UCHL5	ubiquitin carboxyl-terminal hydrolase L5	71909	0.09
chr8_120650260_120650433	0.23	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	674	0.78
chr17_8065024_8065852	0.23	VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	812	0.29
chr4_114216117_114216268	0.23	ANK2	ankyrin 2, neuronal	2054	0.45
chr2_100881771_100881922	0.23	LONRF2	LON peptidase N-terminal domain and ring finger 2	44121	0.17
chr9_117149358_117150269	0.23	AKNA	AT-hook transcription factor	430	0.85
chr17_39804404_39805047	0.23	KRT42P	keratin 42 pseudogene	17881	0.09
chr12_1702254_1703248	0.23	FBXL14	F-box and leucine-rich repeat protein 14	580	0.78
chr2_239768756_239768907	0.23	TWIST2	twist family bHLH transcription factor 2	12158	0.25
chr20_5066459_5066610	0.23	ENSG00000212536	.	12588	0.13
chr20_18658814_18658965	0.23	RP11-379J5.5		20464	0.18
chr17_81008798_81008949	0.23	B3GNTL1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1	813	0.67
chr9_96714559_96714710	0.23	BARX1	BARX homeobox 1	1079	0.63
chr1_19673885_19674036	0.23	PQLC2	PQ loop repeat containing 2	22712	0.11
chr19_1267204_1267424	0.23	CIRBP	cold inducible RNA binding protein	24	0.94
chr8_25143601_25143752	0.23	DOCK5	dedicator of cytokinesis 5	12782	0.27
chr14_81644331_81644507	0.22	RP11-114N19.3		7661	0.22
chr19_2083107_2083981	0.22	MOB3A	MOB kinase activator 3A	1847	0.21
chr7_87935974_87936151	0.22	STEAP4	STEAP family member 4	133	0.97
chr3_14474617_14474768	0.22	SLC6A6	solute carrier family 6 (neurotransmitter transporter), member 6	514	0.83
chr1_161067755_161068142	0.22	KLHDC9	kelch domain containing 9	236	0.81
chr5_32545745_32545896	0.22	SUB1	SUB1 homolog (S. cerevisiae)	13896	0.25
chr5_76372662_76373578	0.22	ENSG00000238961	.	3276	0.17
chr8_89338361_89338512	0.22	RP11-586K2.1		629	0.66
chr17_42082359_42083086	0.22	NAGS	N-acetylglutamate synthase	597	0.46
chr14_92367892_92368043	0.22	FBLN5	fibulin 5	23581	0.18
chr1_16343782_16344178	0.21	HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)	340	0.8
chr1_45082416_45082567	0.21	RNF220	ring finger protein 220	9507	0.17
chr11_406419_406701	0.21	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	190	0.87
chr9_35793134_35793285	0.21	NPR2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)	1058	0.29
chr6_148521629_148521780	0.21	SASH1	SAM and SH3 domain containing 1	71736	0.11
chr18_158238_158410	0.21	USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	59	0.98
chr3_49055259_49056395	0.21	DALRD3	DALR anticodon binding domain containing 3	170	0.84
chr2_145272420_145272698	0.21	ZEB2	zinc finger E-box binding homeobox 2	2556	0.32
chr16_50727533_50728424	0.21	NOD2	nucleotide-binding oligomerization domain containing 2	441	0.74
chr11_1329925_1330473	0.21	TOLLIP	toll interacting protein	650	0.47
chr17_79880835_79881081	0.21	RP11-498C9.12		183	0.67
chr17_74268478_74268686	0.21	UBALD2	UBA-like domain containing 2	6798	0.13
chr8_142288307_142288672	0.21	RP11-10J21.3	Uncharacterized protein	23825	0.12
chr1_12227603_12227877	0.21	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	680	0.65
chr3_87003306_87003457	0.21	VGLL3	vestigial like 3 (Drosophila)	36471	0.24
chr6_169252713_169252864	0.20	SMOC2	SPARC related modular calcium binding 2	199024	0.03
chr10_89824216_89824367	0.20	ENSG00000200891	.	69839	0.12
chr20_3082970_3083121	0.20	UBOX5-AS1	UBOX5 antisense RNA 1	4514	0.13
chr10_28308972_28309123	0.20	ARMC4	armadillo repeat containing 4	21070	0.27
chr2_240202152_240202303	0.20	ENSG00000265215	.	24930	0.16
chr15_40697977_40698740	0.20	IVD	isovaleryl-CoA dehydrogenase	83	0.94
chr11_68658958_68659117	0.20	MRPL21	mitochondrial ribosomal protein L21	12209	0.15
chr6_11279481_11279645	0.20	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	46648	0.16
chr1_15527398_15527585	0.20	C1orf195	chromosome 1 open reading frame 195	29678	0.16
chr15_65136052_65136764	0.20	AC069368.3	Uncharacterized protein	2261	0.2
chr15_90356636_90356804	0.20	ANPEP	alanyl (membrane) aminopeptidase	1374	0.33
chr16_30996962_30997263	0.20	AC135048.1	Uncharacterized protein	421	0.49
chr19_38129236_38129387	0.20	ZFP30	ZFP30 zinc finger protein	16319	0.14
chrX_134124848_134125476	0.20	SMIM10	small integral membrane protein 10	194	0.94
chr10_73533824_73534035	0.20	C10orf54	chromosome 10 open reading frame 54	674	0.7
chr21_33508570_33508721	0.20	ENSG00000264055	.	15572	0.24
chr21_45139141_45140358	0.20	PDXK	pyridoxal (pyridoxine, vitamin B6) kinase	756	0.66
chr5_106724658_106724809	0.20	EFNA5	ephrin-A5	281595	0.01
chr18_7619630_7619781	0.20	PTPRM	protein tyrosine phosphatase, receptor type, M	51888	0.16
chr8_1940163_1940314	0.20	KBTBD11	kelch repeat and BTB (POZ) domain containing 11	18194	0.24
chr3_77090564_77090715	0.20	ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	758	0.77
chr8_144451022_144451484	0.19	RHPN1	rhophilin, Rho GTPase binding protein 1	196	0.76
chr5_138311064_138311215	0.19	ENSG00000201532	.	36879	0.13
chr5_176798199_176798886	0.19	RGS14	regulator of G-protein signaling 14	4598	0.11
chr3_48597891_48598569	0.19	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	332	0.77
chr9_130217644_130218078	0.19	LRSAM1	leucine rich repeat and sterile alpha motif containing 1	3327	0.15
chr15_70433742_70433910	0.19	TLE3	transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)	43311	0.16
chr19_2635140_2635291	0.19	CTC-265F19.3		3263	0.18
chr3_98482698_98482885	0.19	ST3GAL6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	594	0.76
chr7_37123310_37123461	0.19	ENSG00000221157	.	21830	0.22
chr5_150594214_150594453	0.19	GM2A	GM2 ganglioside activator	2622	0.27
chr17_9924881_9925032	0.19	GAS7	growth arrest-specific 7	1497	0.47
chr3_194705554_194705908	0.19	XXYLT1-AS1	XXYLT1 antisense RNA 1	109586	0.06
chr4_138450227_138450378	0.19	PCDH18	protocadherin 18	3263	0.41
chr3_50305285_50305436	0.19	SEMA3B-AS1	SEMA3B antisense RNA 1 (head to head)	557	0.55
chr19_18794852_18795187	0.19	CRTC1	CREB regulated transcription coactivator 1	531	0.72
chr7_72436019_72436572	0.19	TRIM74	tripartite motif containing 74	1189	0.31
chr2_96915646_96915797	0.19	TMEM127	transmembrane protein 127	10612	0.14
chr12_91576386_91576586	0.19	DCN	decorin	0	0.99
chr22_39889594_39889745	0.19	MIEF1	mitochondrial elongation factor 1	6436	0.14
chr7_156432875_156433240	0.19	RNF32	ring finger protein 32	82	0.57
chr1_156466052_156466203	0.19	MEF2D	myocyte enhancer factor 2D	4402	0.14
chr6_112065421_112065572	0.18	FYN	FYN oncogene related to SRC, FGR, YES	14821	0.25
chr4_150999769_151000790	0.18	DCLK2	doublecortin-like kinase 2	99	0.98
chr8_74787469_74787620	0.18	UBE2W	ubiquitin-conjugating enzyme E2W (putative)	3516	0.27
chr10_95262845_95263083	0.18	CEP55	centrosomal protein 55kDa	3803	0.2
chr9_129089520_129090202	0.18	MVB12B	multivesicular body subunit 12B	733	0.77
chr3_114169976_114170457	0.18	ZBTB20	zinc finger and BTB domain containing 20	3314	0.33
chr1_17622086_17622237	0.18	PADI4	peptidyl arginine deiminase, type IV	12529	0.15
chr7_73442859_73443010	0.18	ELN	elastin	416	0.85
chr5_180617301_180618176	0.18	CTC-338M12.5		1186	0.26
chr16_83848003_83848154	0.18	HSBP1	heat shock factor binding protein 1	6484	0.17
chr3_123337936_123338087	0.18	MYLK	myosin light chain kinase	1350	0.45
chr7_18955566_18955717	0.18	AC004744.3		16585	0.27
chr5_134689632_134689991	0.18	C5orf66	chromosome 5 open reading frame 66	16182	0.18
chr19_13319766_13319917	0.18	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	48373	0.08
chr16_30216869_30217924	0.18	RP11-347C12.3	Uncharacterized protein	31	0.94
chr14_65623358_65623814	0.18	ENSG00000222985	.	32326	0.16
chr2_161491867_161492018	0.18	RBMS1	RNA binding motif, single stranded interacting protein 1	141637	0.05
chr16_86603298_86603475	0.18	RP11-463O9.5		2019	0.25
chr19_16293563_16293744	0.18	FAM32A	family with sequence similarity 32, member A	2538	0.18
chr17_56414167_56414399	0.18	BZRAP1-AS1	BZRAP1 antisense RNA 1	281	0.76
chr18_522731_523016	0.18	COLEC12	collectin sub-family member 12	22151	0.15
chr1_100435604_100436270	0.18	SLC35A3	solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3	72	0.88
chr2_101179794_101180035	0.18	PDCL3	phosducin-like 3	194	0.93
chr11_65184608_65185159	0.18	ENSG00000245532	.	27046	0.09
chr5_143265670_143265821	0.18	HMHB1	histocompatibility (minor) HB-1	74019	0.12
chr21_16291045_16291196	0.18	AF127577.8		265	0.93
chr7_73443991_73444142	0.18	ELN	elastin	1548	0.4
chr20_61201262_61201430	0.18	ENSG00000207764	.	39227	0.09
chrX_13268758_13268909	0.18	GS1-600G8.3		59938	0.14
chr1_15850348_15850760	0.18	CASP9	caspase 9, apoptosis-related cysteine peptidase	158	0.92
chr11_69460305_69460629	0.18	CCND1	cyclin D1	4493	0.24
chr2_37894528_37894693	0.18	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	4724	0.31
chr16_2077067_2078193	0.18	SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	701	0.35
chr15_81591495_81592151	0.18	IL16	interleukin 16	66	0.98
chr21_46953280_46953431	0.18	SLC19A1	solute carrier family 19 (folate transporter), member 1	1174	0.53
chr14_92879549_92879700	0.17	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	4901	0.31
chr3_112356424_112356629	0.17	CCDC80	coiled-coil domain containing 80	418	0.88
chr11_46382695_46383612	0.17	DGKZ	diacylglycerol kinase, zeta	8	0.97
chr9_93644008_93644159	0.17	SYK	spleen tyrosine kinase	54313	0.18
chr3_50273853_50274765	0.17	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	673	0.53
chr5_87797997_87798358	0.17	TMEM161B-AS1	TMEM161B antisense RNA 1	75665	0.11
chr19_49378794_49379189	0.17	PPP1R15A	protein phosphatase 1, regulatory subunit 15A	1416	0.22
chr19_1164693_1164844	0.17	SBNO2	strawberry notch homolog 2 (Drosophila)	4174	0.14
chr19_45347719_45348142	0.17	PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	1502	0.27
chr22_50625649_50625946	0.17	TRABD	TraB domain containing	1451	0.21
chr4_42657844_42658977	0.17	ATP8A1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	700	0.59
chr5_172264830_172264981	0.17	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	3491	0.23
chr16_1992323_1993243	0.17	MSRB1	methionine sulfoxide reductase B1	341	0.64
chr10_16869868_16870019	0.17	RSU1	Ras suppressor protein 1	10416	0.28
chr20_32030739_32031661	0.17	SNTA1	syntrophin, alpha 1	498	0.77
chr15_102181178_102181450	0.17	ENSG00000252614	.	7201	0.18
chr17_38488898_38489056	0.17	RARA	retinoic acid receptor, alpha	8663	0.11
chr8_74005587_74005738	0.17	SBSPON	somatomedin B and thrombospondin, type 1 domain containing	155	0.95
chr5_95156034_95156185	0.17	GLRX	glutaredoxin (thioltransferase)	2306	0.24
chr7_44788675_44789485	0.17	ZMIZ2	zinc finger, MIZ-type containing 2	550	0.76
chr2_243030793_243031816	0.17	AC093642.5		460	0.62
chr2_64262064_64262215	0.17	VPS54	vacuolar protein sorting 54 homolog (S. cerevisiae)	15933	0.26
chr2_189652663_189652814	0.17	DIRC1	disrupted in renal carcinoma 1	2093	0.42
chr12_56097264_56097415	0.17	ITGA7	integrin, alpha 7	4146	0.1
chr1_145562437_145562658	0.17	PIAS3	protein inhibitor of activated STAT, 3	12686	0.09
chr6_32076875_32077026	0.17	TNXB	tenascin XB	140	0.9
chr10_22904775_22905136	0.17	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	24313	0.26

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MESP1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.4	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.3	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.6	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.1	0.2	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.1	0.2	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.1	0.3	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.2	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.2	GO:0042663	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.2	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.2	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.2	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.1	0.2	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.2	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.2	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.2	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.1	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.3	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.1	0.2	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.1	0.2	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	0.2	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.2	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.2	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.1	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.1	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0042819	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0071883	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.2	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.7	GO:0048536	spleen development(GO:0048536)
0.0	0.2	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.2	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.2	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.3	GO:0015884	folic acid transport(GO:0015884)
0.0	0.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.2	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0	0.0	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.0	GO:0032493	response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0	0.3	GO:0006853	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.2	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.2	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.0	0.0	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.1	GO:0015780	nucleotide-sugar transport(GO:0015780)
0.0	0.2	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.1	GO:0015809	arginine transport(GO:0015809)
0.0	0.1	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.2	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.0	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.2	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.3	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.0	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.2	GO:0032096	negative regulation of response to food(GO:0032096)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.2	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.1	GO:0071223	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.0	GO:0048845	venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.0	0.1	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.1	GO:0031659	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.2	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.3	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.0	GO:0034393	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.3	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.0	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.1	GO:0033622	integrin activation(GO:0033622)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.0	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0090026	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.2	GO:0090398	cellular senescence(GO:0090398)
0.0	0.1	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.0	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.0	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0	0.2	GO:0034033	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.0	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.2	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) regulation of membrane lipid distribution(GO:0097035)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:2000909	sterol import(GO:0035376) regulation of cholesterol import(GO:0060620) cholesterol import(GO:0070508) regulation of sterol import(GO:2000909)
0.0	0.0	GO:0034143	regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.1	GO:0021794	thalamus development(GO:0021794)
0.0	0.1	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0060424	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.2	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.1	GO:0060324	face development(GO:0060324)
0.0	0.0	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.1	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.1	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.2	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.2	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.3	GO:0009268	response to pH(GO:0009268)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.0	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.0	GO:0033605	positive regulation of catecholamine secretion(GO:0033605)
0.0	0.1	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.0	GO:0001865	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0090151	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0	0.1	GO:0015838	amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0042749	regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.2	GO:0051602	response to electrical stimulus(GO:0051602)
0.0	0.1	GO:0033003	regulation of mast cell activation(GO:0033003)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:2000846	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.0	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0	0.1	GO:0035306	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:0045123	cellular extravasation(GO:0045123)
0.0	0.1	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.0	GO:0010586	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.3	GO:0043487	regulation of RNA stability(GO:0043487)
0.0	0.0	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0070198	protein localization to chromosome, telomeric region(GO:0070198)
0.0	0.2	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.2	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.1	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.0	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.0	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.0	GO:0090273	somatostatin secretion(GO:0070253) regulation of somatostatin secretion(GO:0090273)
0.0	0.0	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0001914	regulation of T cell mediated cytotoxicity(GO:0001914)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.0	GO:0051974	negative regulation of telomerase activity(GO:0051974) negative regulation of DNA biosynthetic process(GO:2000279)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.1	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.0	GO:0072047	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0019884	antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.0	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.1	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0009209	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.2	GO:0010171	body morphogenesis(GO:0010171)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0030432	peristalsis(GO:0030432)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.3	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.0	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.0	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.1	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.0	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.4	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0048241	epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0019042	viral latency(GO:0019042)
0.0	0.0	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.0	0.0	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.0	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.0	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0072676	lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0	0.0	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.3	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.0	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.0	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.2	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.0	GO:1902808	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.0	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.3	GO:0034968	histone lysine methylation(GO:0034968)
0.0	0.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.1	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.0	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.0	GO:1902117	positive regulation of organelle assembly(GO:1902117)
0.0	0.3	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:1902115	regulation of organelle assembly(GO:1902115)
0.0	0.2	GO:0007030	Golgi organization(GO:0007030)
0.0	0.1	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385) microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0046386	deoxyribose phosphate catabolic process(GO:0046386)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0018206	peptidyl-methionine modification(GO:0018206)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0030904	retromer complex(GO:0030904)
0.1	0.2	GO:0043218	compact myelin(GO:0043218)
0.1	0.2	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.2	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.3	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.2	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.3	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.0	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.0	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.2	GO:0016235	aggresome(GO:0016235)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.5	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0016234	inclusion body(GO:0016234)
0.0	0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.0	GO:0001740	Barr body(GO:0001740)
0.0	0.0	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.2	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0	0.0	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.8	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1	0.3	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.5	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.1	0.4	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.3	GO:0008518	reduced folate carrier activity(GO:0008518)
0.1	0.2	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.2	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.4	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.0	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.2	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.3	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.2	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.3	GO:0046969	histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0004739	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0019956	chemokine binding(GO:0019956)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.0	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.3	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.0	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.6	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0004953	icosanoid receptor activity(GO:0004953)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.1	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.0	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0	0.2	GO:0004675	transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.2	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.0	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.0	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.0	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.0	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.3	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.1	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.0	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.0	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.0	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.0	GO:0042806	fucose binding(GO:0042806)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0032404	mismatch repair complex binding(GO:0032404)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.0	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.2	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.2	GO:0015923	mannosidase activity(GO:0015923)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.8	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.5	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.3	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	SIG CHEMOTAXIS	Genes related to chemotaxis
0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.1	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.5	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.1	PID RAC1 PATHWAY	RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
0.3	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.4	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.7	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.2	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.4	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.4	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin

Results for MESP1

Z-value: 1.18

Motif logo

Transcription factors associated with MESP1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the MESP1 motif across conditions

Conditions sorted by the z-value of the MESP1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MESP1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: