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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for MSX1

Z-value: 0.80

Motif logo

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Transcription factors associated with MSX1

Gene Symbol Gene ID Gene Info
MSX1
ENSG00000163132.6 msh homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_4873247_4873398MSX1119290.255507-0.618.0e-02Click!
chr4_4765683_4765834MSX1956350.079346-0.531.4e-01Click!
chr4_4873038_4873189MSX1117200.256232-0.511.6e-01Click!
chr4_4854523_4854767MSX167480.2876950.501.7e-01Click!
chr4_4861125_4861397MSX11320.9764610.472.0e-01Click!

Activity of the MSX1 motif across conditions

Conditions sorted by the z-value of the MSX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_38172411_38172686 0.47 POSTN
 periostin, osteoblast specific factor
 315
 0.95
chr3_129468296_129468447 0.38 TMCC1
 transmembrane and coiled-coil domain family 1
 44888
 0.13
chr6_1613704_1614304 0.35 FOXC1
 forkhead box C1
 3323
 0.37
chr6_1612835_1613496 0.34 FOXC1
 forkhead box C1
 2484
 0.42
chr1_234675056_234675207 0.31 ENSG00000212144
 .
 53890
 0.11
chr3_189932576_189932727 0.28 ENSG00000212489
 .
 49339
 0.13
chr3_29327656_29328192 0.27 RBMS3-AS3
 RBMS3 antisense RNA 3
 4293
 0.26
chr9_4865980_4866131 0.26 AL158147.2
 HCG2011465; Uncharacterized protein
 6795
 0.16
chr7_158609578_158609780 0.25 ESYT2
 extended synaptotagmin-like protein 2
 12484
 0.24
chr1_172313169_172313650 0.25 ENSG00000252354
 .
 3874
 0.23
chr8_10268256_10268407 0.25 RP11-981G7.1
22851
 0.2
chr7_116347101_116347278 0.25 MET
 met proto-oncogene
 8050
 0.26
chr15_93429972_93430811 0.25 CHD2
 chromodomain helicase DNA binding protein 2
 3865
 0.22
chr11_14375529_14375805 0.24 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
 379
 0.91
chr18_19866097_19866248 0.24 ENSG00000238907
 .
 25633
 0.19
chr5_106791734_106791885 0.23 EFNA5
 ephrin-A5
 214519
 0.02
chr21_36256046_36256553 0.23 RUNX1
 runt-related transcription factor 1
 3181
 0.38
chr8_83181283_83181434 0.23 SNX16
 sorting nexin 16
 426257
 0.01
chr3_30289901_30290052 0.23 ENSG00000199927
 .
 56051
 0.15
chr9_10292066_10292217 0.22 PTPRD
 protein tyrosine phosphatase, receptor type, D
 258351
 0.02
chr2_225672771_225672922 0.22 DOCK10
 dedicator of cytokinesis 10
 8523
 0.32
chr2_21445047_21445198 0.21 TDRD15
 tudor domain containing 15
 98333
 0.09
chr9_114506322_114506473 0.21 C9orf84
 chromosome 9 open reading frame 84
 15416
 0.21
chr4_61665381_61665532 0.21 ENSG00000265829
 .
 122881
 0.06
chr6_155544928_155545289 0.20 TIAM2
 T-cell lymphoma invasion and metastasis 2
 7008
 0.22
chr21_29172171_29172322 0.20 ADAMTS5
 ADAM metallopeptidase with thrombospondin type 1 motif, 5
 833414
 0.0
chr16_1069426_1069639 0.20 SOX8
 SRY (sex determining region Y)-box 8
 37724
 0.09
chr10_8635845_8635996 0.20 ENSG00000212505
 .
 62874
 0.16
chr9_81871537_81871846 0.20 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 314997
 0.01
chr5_94951954_94952105 0.20 GPR150
 G protein-coupled receptor 150
 3753
 0.21
chr5_26332801_26332952 0.20 ENSG00000222560
 .
 319878
 0.01
chr11_95906977_95907128 0.20 ENSG00000266192
 .
 167550
 0.03
chr8_32407136_32407287 0.20 NRG1
 neuregulin 1
 966
 0.71
chrY_17603350_17603501 0.20 ENSG00000252664
 .
 571221
 0.0
chr22_46479348_46479691 0.19 FLJ27365
 hsa-mir-4763
 2364
 0.16
chr10_80549668_80549819 0.19 ENSG00000223243
 .
 39384
 0.22
chr3_134091064_134091340 0.19 AMOTL2
 angiomotin like 2
 448
 0.85
chr3_49447935_49448923 0.19 RHOA
 ras homolog family member A
 932
 0.32
chr15_93999319_93999470 0.19 ENSG00000212063
 .
 169842
 0.04
chr4_43019583_43019734 0.19 GRXCR1
 glutaredoxin, cysteine rich 1
 124374
 0.06
chr4_47491811_47491962 0.19 ATP10D
 ATPase, class V, type 10D
 4570
 0.24
chr1_221330964_221331115 0.19 HLX
 H2.0-like homeobox
 276455
 0.01
chr4_14728626_14728777 0.18 ENSG00000202449
 .
 36367
 0.24
chr12_54089934_54090280 0.18 CALCOCO1
 calcium binding and coiled-coil domain 1
 18306
 0.14
chr21_25900554_25900705 0.18 ENSG00000232512
 .
 572816
 0.0
chr7_113054663_113054814 0.18 TSRM
 Uncharacterized protein; Zinc finger domain-related protein TSRM
 36389
 0.24
chr1_113447611_113447762 0.18 SLC16A1
 solute carrier family 16 (monocarboxylate transporter), member 1
 30924
 0.18
chr17_2879197_2879355 0.18 CTD-3060P21.1
10087
 0.23
chr9_74377079_74377230 0.18 TMEM2
 transmembrane protein 2
 6148
 0.31
chr11_39124455_39124606 0.18 ENSG00000201591
 .
 158127
 0.04
chr1_244504765_244505074 0.18 C1orf100
 chromosome 1 open reading frame 100
 11018
 0.25
chr4_184558081_184558479 0.18 ENSG00000252157
 .
 16549
 0.14
chr6_69548767_69548918 0.18 BAI3
 brain-specific angiogenesis inhibitor 3
 203583
 0.03
chr10_20208323_20208474 0.18 PLXDC2
 plexin domain containing 2
 103230
 0.07
chr16_82664556_82664707 0.18 CDH13
 cadherin 13
 3933
 0.35
chr7_55638778_55639418 0.18 VOPP1
 vesicular, overexpressed in cancer, prosurvival protein 1
 463
 0.8
chr10_63843987_63844138 0.18 ENSG00000221094
 .
 31912
 0.19
chr4_146467351_146467609 0.18 SMAD1-AS1
 SMAD1 antisense RNA 1
 29210
 0.17
chr2_189198683_189198972 0.18 ENSG00000207951
 .
 36608
 0.17
chr15_67374785_67374936 0.17 SMAD3
 SMAD family member 3
 16060
 0.25
chr2_134432207_134432889 0.17 ENSG00000200708
 .
 78886
 0.11
chr2_113545549_113545700 0.17 IL1A
 interleukin 1, alpha
 3457
 0.21
chr20_43975692_43975843 0.17 SDC4
 syndecan 4
 1297
 0.32
chr15_64813512_64813804 0.17 ZNF609
 zinc finger protein 609
 22167
 0.15
chr6_1798343_1798634 0.17 FOXC1
 forkhead box C1
 187807
 0.03
chr1_189407668_189407819 0.17 ENSG00000252553
 .
 227643
 0.02
chr2_214003351_214003502 0.17 IKZF2
 IKAROS family zinc finger 2 (Helios)
 9927
 0.3
chr17_1478282_1478467 0.17 PITPNA
 phosphatidylinositol transfer protein, alpha
 12264
 0.11
chr12_128113659_128113866 0.17 ENSG00000199584
 .
 9770
 0.33
chr2_113958350_113958501 0.17 PSD4
 pleckstrin and Sec7 domain containing 4
 4568
 0.16
chr3_58359199_58359350 0.17 PXK
 PX domain containing serine/threonine kinase
 22127
 0.17
chr4_169553357_169553551 0.17 PALLD
 palladin, cytoskeletal associated protein
 686
 0.73
chr7_37349873_37350077 0.17 ELMO1
 engulfment and cell motility 1
 32392
 0.18
chr1_120191467_120191618 0.17 ZNF697
 zinc finger protein 697
 1146
 0.52
chr4_85553592_85553743 0.17 CDS1
 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
 49535
 0.15
chr2_118855601_118855752 0.17 INSIG2
 insulin induced gene 2
 9626
 0.24
chrX_2507647_2507798 0.17 CD99P1
 CD99 molecule pseudogene 1
 19734
 0.22
chrY_2457647_2457798 0.17 ENSG00000251841
 .
 195068
 0.03
chr21_41095530_41095681 0.17 IGSF5
 immunoglobulin superfamily, member 5
 21729
 0.21
chr11_12132484_12132785 0.17 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 496
 0.87
chr1_44792092_44792243 0.17 ERI3
 ERI1 exoribonuclease family member 3
 3452
 0.22
chr19_19514440_19514591 0.17 CTB-184G21.3
1103
 0.38
chr11_102183446_102183978 0.17 ENSG00000212466
 .
 741
 0.64
chr21_36771263_36771477 0.16 ENSG00000211590
 .
 321643
 0.01
chr2_175708769_175708920 0.16 CHN1
 chimerin 1
 2289
 0.38
chr5_95564073_95564224 0.16 ENSG00000206997
 .
 18217
 0.26
chr14_51242372_51242693 0.16 NIN
 ninein (GSK3B interacting protein)
 9019
 0.17
chr3_145437289_145437440 0.16 RP11-274H2.5
342102
 0.01
chr3_43735748_43735899 0.16 ANO10
 anoctamin 10
 2737
 0.3
chr8_102898890_102899041 0.16 ENSG00000238372
 .
 39377
 0.2
chr17_5268697_5268848 0.16 RP11-420A6.2
6149
 0.15
chr4_8702215_8702366 0.16 CPZ
 carboxypeptidase Z
 98593
 0.07
chr9_4137636_4137913 0.16 GLIS3
 GLIS family zinc finger 3
 7419
 0.28
chr21_18884161_18884312 0.16 CXADR
 coxsackie virus and adenovirus receptor
 464
 0.77
chr15_71391266_71391417 0.16 THSD4
 thrombospondin, type I, domain containing 4
 2050
 0.37
chr2_52029885_52030036 0.16 ENSG00000222692
 .
 367604
 0.01
chr6_39772789_39772940 0.16 DAAM2
 dishevelled associated activator of morphogenesis 2
 12070
 0.26
chr5_19885020_19885171 0.16 CDH18
 cadherin 18, type 2
 1286
 0.64
chr1_230223080_230223231 0.16 GALNT2
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
 20137
 0.23
chr3_15482302_15482608 0.16 EAF1-AS1
 EAF1 antisense RNA 1
 354
 0.48
chr20_52214556_52214707 0.16 ZNF217
 zinc finger protein 217
 4253
 0.23
chr9_78870959_78871162 0.16 PCSK5
 proprotein convertase subtilisin/kexin type 5
 67505
 0.13
chr5_32991481_32991632 0.15 AC026703.1
202611
 0.03
chr13_19683905_19684056 0.15 ENSG00000252287
 .
 21353
 0.16
chr5_95457320_95457471 0.15 ENSG00000207578
 .
 42553
 0.17
chr1_181455866_181456017 0.15 CACNA1E
 calcium channel, voltage-dependent, R type, alpha 1E subunit
 3060
 0.4
chr4_38754112_38754445 0.15 ENSG00000222230
 .
 6235
 0.19
chr20_49110116_49110267 0.15 PTPN1
 protein tyrosine phosphatase, non-receptor type 1
 16700
 0.18
chr7_101457714_101458422 0.15 CUX1
 cut-like homeobox 1
 891
 0.64
chr15_73926288_73926474 0.15 NPTN
 neuroplastin
 94
 0.98
chr5_142217391_142217542 0.15 ARHGAP26-AS1
 ARHGAP26 antisense RNA 1
 31009
 0.21
chr1_116222239_116222390 0.15 VANGL1
 VANGL planar cell polarity protein 1
 28291
 0.19
chr18_24083489_24083640 0.15 KCTD1
 potassium channel tetramerization domain containing 1
 43399
 0.17
chr7_116416437_116416588 0.15 MET
 met proto-oncogene
 717
 0.73
chr7_27190645_27191214 0.15 HOXA-AS3
 HOXA cluster antisense RNA 3
 1258
 0.18
chr8_27983413_27983564 0.15 ELP3
 elongator acetyltransferase complex subunit 3
 32524
 0.17
chr14_69015576_69015827 0.15 CTD-2325P2.4
79461
 0.1
chr5_142775880_142776681 0.15 NR3C1
 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
 4137
 0.35
chr22_22204157_22204308 0.15 MAPK1
 mitogen-activated protein kinase 1
 17498
 0.14
chr21_15922641_15922820 0.15 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
 4066
 0.28
chr4_160248318_160248469 0.15 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
 4385
 0.29
chr10_97154342_97154493 0.15 SORBS1
 sorbin and SH3 domain containing 1
 21035
 0.25
chr12_62115825_62115976 0.15 FAM19A2
 family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
 105114
 0.08
chr5_94384750_94385033 0.15 MCTP1
 multiple C2 domains, transmembrane 1
 31700
 0.22
chr18_61447047_61447198 0.14 SERPINB7
 serpin peptidase inhibitor, clade B (ovalbumin), member 7
 1911
 0.39
chr2_206543328_206543479 0.14 NRP2
 neuropilin 2
 3821
 0.34
chr1_172290167_172290671 0.14 ENSG00000252354
 .
 26864
 0.17
chr4_35782309_35782460 0.14 ENSG00000206665
 .
 284864
 0.01
chr1_189628853_189629004 0.14 ENSG00000252553
 .
 6458
 0.35
chr3_187467694_187467973 0.14 BCL6
 B-cell CLL/lymphoma 6
 4318
 0.26
chr12_69731656_69731807 0.14 LYZ
 lysozyme
 10390
 0.17
chr16_87522864_87523015 0.14 ZCCHC14
 zinc finger, CCHC domain containing 14
 2712
 0.29
chr11_119089001_119089152 0.14 CBL
 Cbl proto-oncogene, E3 ubiquitin protein ligase
 12324
 0.1
chr5_44620644_44620795 0.14 ENSG00000263556
 .
 95573
 0.09
chr4_157873991_157874142 0.14 PDGFC
 platelet derived growth factor C
 17989
 0.21
chr2_161331149_161331300 0.14 RBMS1
 RNA binding motif, single stranded interacting protein 1
 18805
 0.24
chr4_157860820_157861106 0.14 PDGFC
 platelet derived growth factor C
 31092
 0.19
chr16_46655371_46655551 0.14 SHCBP1
 SHC SH2-domain binding protein 1
 77
 0.97
chr10_134513988_134514364 0.14 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 65152
 0.12
chr12_59434723_59435248 0.14 RP11-150C16.1
120565
 0.06
chr10_69865396_69865547 0.14 MYPN
 myopalladin
 441
 0.84
chr1_28575788_28575939 0.14 RP5-1092A3.4
7899
 0.11
chr11_104838069_104839428 0.14 CASP4
 caspase 4, apoptosis-related cysteine peptidase
 1345
 0.45
chr9_111207460_111207611 0.14 ENSG00000222512
 .
 86326
 0.11
chr1_98816414_98816565 0.14 ENSG00000221777
 .
 22452
 0.29
chr8_93887341_93887492 0.14 ENSG00000248858
 .
 2449
 0.28
chr18_61535025_61535176 0.14 SERPINB2
 serpin peptidase inhibitor, clade B (ovalbumin), member 2
 3826
 0.24
chr17_32078540_32078804 0.14 ENSG00000221699
 .
 122805
 0.05
chr2_26100038_26101197 0.14 ASXL2
 additional sex combs like 2 (Drosophila)
 718
 0.76
chr2_207987855_207988006 0.14 KLF7-IT1
 KLF7 intronic transcript 1 (non-protein coding)
 1162
 0.49
chr15_64391220_64391371 0.14 SNX1
 sorting nexin 1
 3070
 0.19
chr5_80210177_80210328 0.14 CTC-459I6.1
38547
 0.18
chr9_102849500_102849651 0.13 ERP44
 endoplasmic reticulum protein 44
 11747
 0.18
chr12_85768780_85768931 0.13 ALX1
 ALX homeobox 1
 94970
 0.09
chr6_136256925_136257180 0.13 ENSG00000238921
 .
 21159
 0.21
chr13_71667523_71667674 0.13 ENSG00000202433
 .
 634002
 0.0
chr12_22435490_22435710 0.13 ST8SIA1
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
 33620
 0.22
chr5_129840711_129840862 0.13 ENSG00000252514
 .
 118413
 0.07
chr4_116464375_116464526 0.13 NDST4
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
 429418
 0.01
chr9_99391498_99391649 0.13 CDC14B
 cell division cycle 14B
 9461
 0.24
chr11_37129867_37130018 0.13 RAG2
 recombination activating gene 2
 510156
 0.0
chr5_67586145_67586431 0.13 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 177
 0.97
chr1_197730742_197731002 0.13 RP11-448G4.4
4423
 0.25
chr7_82070146_82070432 0.13 CACNA2D1
 calcium channel, voltage-dependent, alpha 2/delta subunit 1
 2742
 0.43
chr20_24270294_24270445 0.13 ENSG00000200231
 .
 52478
 0.18
chr19_11466484_11467017 0.13 DKFZP761J1410
 Lipid phosphate phosphatase-related protein type 2
 576
 0.52
chr4_181237914_181238065 0.13 NA
 NA
 > 106
 NA
chr21_18785623_18785774 0.13 ENSG00000252462
 .
 18167
 0.18
chr1_220527416_220527567 0.13 AC096644.1
 Uncharacterized protein
 80532
 0.09
chr20_50722770_50722921 0.13 ZFP64
 ZFP64 zinc finger protein
 662
 0.82
chr14_93720610_93720761 0.13 UBR7
 ubiquitin protein ligase E3 component n-recognin 7 (putative)
 35658
 0.11
chr22_24917713_24917864 0.13 AP000355.2
5312
 0.15
chr6_108886554_108887901 0.13 FOXO3
 forkhead box O3
 5158
 0.32
chr12_5427929_5428080 0.13 NTF3
 neurotrophin 3
 113275
 0.07
chr15_31734664_31735087 0.13 KLF13
 Kruppel-like factor 13
 76518
 0.12
chr9_21548772_21548928 0.13 MIR31HG
 MIR31 host gene (non-protein coding)
 10818
 0.17
chr10_91811914_91812065 0.13 ENSG00000222451
 .
 111728
 0.07
chr4_177931083_177931234 0.13 ENSG00000222859
 .
 171438
 0.03
chr3_151033417_151033568 0.13 GPR87
 G protein-coupled receptor 87
 1248
 0.43
chr3_42191892_42192043 0.13 TRAK1
 trafficking protein, kinesin binding 1
 1240
 0.57
chr18_59666248_59666399 0.13 RNF152
 ring finger protein 152
 104859
 0.07
chr18_3351537_3351688 0.13 TGIF1
 TGFB-induced factor homeobox 1
 59994
 0.1
chr10_105609571_105609851 0.13 SH3PXD2A
 SH3 and PX domains 2A
 5453
 0.22
chr6_98415844_98415995 0.13 ENSG00000238367
 .
 56488
 0.18
chr20_49272065_49272493 0.13 RP4-530I15.6
2540
 0.24
chr6_72970806_72970957 0.13 RIMS1
 regulating synaptic membrane exocytosis 1
 8387
 0.27
chr9_21677527_21678485 0.13 ENSG00000244230
 .
 21307
 0.21
chr5_153827010_153827219 0.13 SAP30L
 SAP30-like
 1009
 0.44
chr4_187686004_187686155 0.13 FAT1
 FAT atypical cadherin 1
 38203
 0.2
chr9_286081_286232 0.13 DOCK8
 dedicator of cytokinesis 8
 13086
 0.19
chr2_206678700_206678851 0.13 AC007362.3
50045
 0.15
chr3_45986008_45986159 0.13 CXCR6
 chemokine (C-X-C motif) receptor 6
 428
 0.8
chr10_27771901_27772052 0.13 RAB18
 RAB18, member RAS oncogene family
 21221
 0.22
chr10_111794329_111794480 0.13 ADD3
 adducin 3 (gamma)
 26682
 0.18
chr7_74077316_74077467 0.12 GTF2I
 general transcription factor IIi
 5034
 0.25
chr17_41281323_41281529 0.12 NBR2
 neighbor of BRCA1 gene 2 (non-protein coding)
 1799
 0.26
chr9_26262415_26262566 0.12 ENSG00000266429
 .
 351633
 0.01
chr2_195590152_195590303 0.12 ENSG00000252517
 .
 61329
 0.16
chr4_48701192_48701343 0.12 FRYL
 FRY-like
 18079
 0.24
chr4_180046351_180046502 0.12 ENSG00000212191
 .
 439316
 0.01

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.2 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.0 0.1 GO:0060044 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.1 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.0 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.0 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0060430 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0 0.0 GO:0030540 female genitalia development(GO:0030540)
0.0 0.1 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.0 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions