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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for MYF6

Z-value: 0.87

Motif logo

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Transcription factors associated with MYF6

Gene Symbol Gene ID Gene Info
MYF6
ENSG00000111046.3 MYF6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
MYF6chr12_81092154_8109230590480.211378-0.713.0e-02Click!
MYF6chr12_81102183_8110293512820.485596-0.511.6e-01Click!
MYF6chr12_81064372_81064523368300.146841-0.442.4e-01Click!
MYF6chr12_81096783_8109704243650.241896-0.343.7e-01Click!
MYF6chr12_81097059_8109735640700.247165-0.333.8e-01Click!

Activity of the MYF6 motif across conditions

Conditions sorted by the z-value of the MYF6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_441089_441413 0.45 ENSG00000243562
 .
 558
 0.44
chr1_2347262_2347748 0.37 PEX10
 peroxisomal biogenesis factor 10
 2269
 0.17
chr1_174768895_174769046 0.30 RABGAP1L
 RAB GTPase activating protein 1-like
 100
 0.98
chr17_80260072_80260536 0.29 CD7
 CD7 molecule
 15124
 0.1
chr2_191745621_191745919 0.28 GLS
 glutaminase
 210
 0.9
chr11_1482189_1482340 0.26 BRSK2
 BR serine/threonine kinase 2
 10349
 0.17
chrX_39186546_39186697 0.26 ENSG00000207122
 .
 246083
 0.02
chr12_76424698_76425269 0.26 PHLDA1
 pleckstrin homology-like domain, family A, member 1
 401
 0.66
chr14_61788916_61789580 0.26 PRKCH
 protein kinase C, eta
 134
 0.7
chr11_58873962_58874353 0.25 FAM111B
 family with sequence similarity 111, member B
 501
 0.79
chr16_68798920_68799109 0.25 ENSG00000200558
 .
 22631
 0.14
chr11_46367528_46367907 0.25 DGKZ
 diacylglycerol kinase, zeta
 730
 0.6
chr18_2967390_2967541 0.24 RP11-737O24.1
449
 0.78
chr6_209971_210123 0.24 DUSP22
 dual specificity phosphatase 22
 81583
 0.11
chr22_21738155_21738638 0.23 RIMBP3B
 RIMS binding protein 3B
 733
 0.51
chr3_29495707_29495858 0.23 ENSG00000216169
 .
 84870
 0.1
chr5_156535881_156536093 0.23 HAVCR2
 hepatitis A virus cellular receptor 2
 146
 0.94
chr22_20460794_20461266 0.23 RIMBP3
 RIMS binding protein 3
 756
 0.52
chr3_12689624_12689775 0.22 ENSG00000239140
 .
 15466
 0.17
chr5_180017657_180017884 0.22 SCGB3A1
 secretoglobin, family 3A, member 1
 770
 0.62
chr19_6060885_6061036 0.22 RFX2
 regulatory factor X, 2 (influences HLA class II expression)
 3666
 0.18
chr22_39963541_39963692 0.22 CACNA1I
 calcium channel, voltage-dependent, T type, alpha 1I subunit
 3142
 0.23
chr22_21904755_21905186 0.21 RIMBP3C
 RIMS binding protein 3C
 150
 0.88
chr16_14380187_14380356 0.21 ENSG00000201075
 .
 10909
 0.18
chr17_62009073_62009653 0.21 CD79B
 CD79b molecule, immunoglobulin-associated beta
 258
 0.86
chr18_13376586_13376737 0.21 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
 5892
 0.17
chr11_441985_442183 0.21 ANO9
 anoctamin 9
 73
 0.92
chr2_68966105_68966288 0.21 ARHGAP25
 Rho GTPase activating protein 25
 4182
 0.3
chr19_5132131_5132282 0.21 CTC-482H14.5
45924
 0.14
chr12_112036778_112037095 0.21 ATXN2
 ataxin 2
 218
 0.66
chr14_22554936_22555087 0.21 ENSG00000238634
 .
 55876
 0.15
chr21_36217976_36218127 0.20 RUNX1
 runt-related transcription factor 1
 41429
 0.2
chr1_116096403_116096554 0.20 ENSG00000239984
 .
 52614
 0.13
chr13_26624895_26625081 0.20 SHISA2
 shisa family member 2
 181
 0.97
chr7_130007608_130007759 0.20 CPA5
 carboxypeptidase A5
 4401
 0.15
chr16_68771339_68771490 0.20 CDH1
 cadherin 1, type 1, E-cadherin (epithelial)
 159
 0.94
chr8_128988445_128988635 0.20 ENSG00000221771
 .
 15661
 0.16
chr12_19592806_19593080 0.20 AEBP2
 AE binding protein 2
 310
 0.92
chr11_2320607_2320858 0.20 C11orf21
 chromosome 11 open reading frame 21
 2411
 0.18
chr1_100819629_100819780 0.20 CDC14A
 cell division cycle 14A
 1199
 0.48
chr8_62626758_62627054 0.19 ASPH
 aspartate beta-hydroxylase
 178
 0.78
chr5_35857770_35858187 0.19 IL7R
 interleukin 7 receptor
 984
 0.58
chr22_24824729_24824978 0.19 ADORA2A
 adenosine A2a receptor
 1323
 0.44
chr12_7068113_7068279 0.19 ENSG00000207713
 .
 4666
 0.06
chr8_21770420_21771232 0.19 DOK2
 docking protein 2, 56kDa
 348
 0.88
chr20_62369505_62369786 0.19 RP4-583P15.14
22
 0.92
chr17_38250724_38250875 0.19 NR1D1
 nuclear receptor subfamily 1, group D, member 1
 6179
 0.12
chr18_43266884_43267229 0.19 SLC14A2
 solute carrier family 14 (urea transporter), member 2
 20949
 0.17
chr19_19737943_19738234 0.19 LPAR2
 lysophosphatidic acid receptor 2
 521
 0.66
chr1_201438452_201438736 0.18 PHLDA3
 pleckstrin homology-like domain, family A, member 3
 229
 0.92
chr1_2455307_2455458 0.18 PANK4
 pantothenate kinase 4
 2653
 0.14
chrX_78403286_78403508 0.18 GPR174
 G protein-coupled receptor 174
 23072
 0.28
chr1_185528978_185529129 0.18 ENSG00000207108
 .
 70607
 0.11
chr1_26644827_26645344 0.18 UBXN11
 UBX domain protein 11
 231
 0.76
chr14_93043697_93043848 0.18 RIN3
 Ras and Rab interactor 3
 63624
 0.13
chr7_150148052_150148382 0.18 GIMAP8
 GTPase, IMAP family member 8
 499
 0.78
chr11_122568313_122568557 0.18 ENSG00000239079
 .
 28584
 0.19
chr16_1031099_1031287 0.18 AC009041.2
59
 0.53
chr7_45076135_45076286 0.18 CCM2
 cerebral cavernous malformation 2
 8939
 0.15
chr8_65607910_65608061 0.18 RP11-1D12.1
39031
 0.2
chr16_3628507_3629057 0.18 NLRC3
 NLR family, CARD domain containing 3
 1381
 0.35
chr2_148779045_148779339 0.18 ORC4
 origin recognition complex, subunit 4
 45
 0.92
chr22_28194756_28194907 0.18 MN1
 meningioma (disrupted in balanced translocation) 1
 2655
 0.36
chr1_36023709_36024187 0.18 NCDN
 neurochondrin
 159
 0.86
chr13_78271067_78271525 0.18 SLAIN1
 SLAIN motif family, member 1
 727
 0.51
chr17_14204490_14204770 0.18 HS3ST3B1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
 230
 0.95
chr12_258585_258736 0.18 RP11-598F7.4
325
 0.85
chr1_90468959_90469110 0.17 ZNF326
 zinc finger protein 326
 8307
 0.24
chr1_27847952_27848103 0.17 RP1-159A19.4
4289
 0.2
chr8_145003826_145003977 0.17 PLEC
 plectin
 2722
 0.16
chr17_1478951_1479102 0.17 PITPNA
 phosphatidylinositol transfer protein, alpha
 12916
 0.11
chr1_43415165_43415361 0.17 SLC2A1
 solute carrier family 2 (facilitated glucose transporter), member 1
 9237
 0.19
chr1_160547005_160547156 0.17 CD84
 CD84 molecule
 2183
 0.25
chr2_5768317_5769063 0.17 AC108025.2
62488
 0.12
chr13_50645613_50645841 0.17 DLEU1
 deleted in lymphocytic leukemia 1 (non-protein coding)
 10580
 0.16
chr4_48655659_48656132 0.17 FRYL
 FRY-like
 19468
 0.24
chr16_1392661_1392945 0.17 BAIAP3
 BAI1-associated protein 3
 1866
 0.16
chr1_110333243_110333394 0.17 EPS8L3
 EPS8-like 3
 26669
 0.13
chr11_108408827_108408978 0.17 EXPH5
 exophilin 5
 32
 0.98
chr4_16219327_16219478 0.17 TAPT1
 transmembrane anterior posterior transformation 1
 8692
 0.2
chr2_112940458_112940634 0.17 FBLN7
 fibulin 7
 1086
 0.59
chr12_47610316_47610761 0.17 PCED1B
 PC-esterase domain containing 1B
 157
 0.96
chr4_140910160_140910334 0.17 MAML3
 mastermind-like 3 (Drosophila)
 98126
 0.08
chrX_10514569_10514720 0.16 MID1
 midline 1 (Opitz/BBB syndrome)
 30351
 0.21
chr15_38854702_38854853 0.16 RASGRP1
 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
 2059
 0.32
chr2_242843781_242843932 0.16 AC131097.4
 Protein LOC285095
 846
 0.53
chr19_6590606_6591184 0.16 CD70
 CD70 molecule
 255
 0.89
chr14_22947996_22948147 0.16 ENSG00000251002
 .
 2207
 0.16
chr14_106855204_106855368 0.16 IGHV3-37
 immunoglobulin heavy variable 3-37 (pseudogene)
 2260
 0.07
chr8_24855476_24855627 0.16 CTD-2168K21.2
41416
 0.17
chr1_200882421_200882682 0.16 C1orf106
 chromosome 1 open reading frame 106
 18602
 0.16
chr7_150180608_150181504 0.16 GIMAP7
 GTPase, IMAP family member 7
 30862
 0.13
chr7_152209916_152210186 0.16 ENSG00000221454
 .
 73745
 0.08
chr15_44958533_44958684 0.16 PATL2
 protein associated with topoisomerase II homolog 2 (yeast)
 2075
 0.24
chr12_120033969_120034120 0.16 TMEM233
 transmembrane protein 233
 2780
 0.25
chr16_28996496_28996848 0.16 LAT
 linker for activation of T cells
 11
 0.94
chr2_10472002_10472153 0.16 HPCAL1
 hippocalcin-like 1
 28251
 0.15
chr5_176784926_176785308 0.16 RGS14
 regulator of G-protein signaling 14
 279
 0.82
chr20_31071096_31071265 0.16 C20orf112
 chromosome 20 open reading frame 112
 94
 0.97
chr8_117168069_117168220 0.16 ENSG00000221793
 .
 19146
 0.28
chr21_44834894_44835045 0.16 SIK1
 salt-inducible kinase 1
 12039
 0.28
chr16_28634523_28635087 0.16 SULT1A1
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
 69
 0.96
chr18_10131788_10132277 0.16 ENSG00000263630
 .
 126838
 0.05
chr11_5735144_5735295 0.16 TRIM22
 tripartite motif containing 22
 5781
 0.13
chr8_121744015_121744417 0.16 RP11-713M15.1
29277
 0.22
chr5_1315874_1316496 0.16 ENSG00000263670
 .
 6693
 0.18
chr2_16083664_16083952 0.16 MYCNOS
 MYCN opposite strand
 1437
 0.36
chr13_28696488_28696678 0.16 PAN3-AS1
 PAN3 antisense RNA 1
 15747
 0.17
chr2_131673224_131673375 0.16 ARHGEF4
 Rho guanine nucleotide exchange factor (GEF) 4
 925
 0.59
chr20_34078435_34078749 0.16 RP3-477O4.14
151
 0.92
chr9_92094215_92094379 0.15 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 508
 0.83
chr2_71687821_71687972 0.15 DYSF
 dysferlin
 5936
 0.27
chr1_207244089_207244240 0.15 PFKFB2
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
 5815
 0.14
chr8_128492794_128493088 0.15 CASC8
 cancer susceptibility candidate 8 (non-protein coding)
 1443
 0.55
chr6_144655565_144656031 0.15 RP1-91J24.3
1361
 0.51
chrX_68725182_68725333 0.15 FAM155B
 family with sequence similarity 155, member B
 173
 0.88
chr4_144435743_144436361 0.15 SMARCA5-AS1
 SMARCA5 antisense RNA 1
 264
 0.9
chr5_147184374_147184525 0.15 JAKMIP2
 janus kinase and microtubule interacting protein 2
 22111
 0.17
chr1_173376102_173376280 0.15 RP11-296O14.3
35045
 0.18
chr14_61811311_61811517 0.15 PRKCH
 protein kinase C, eta
 372
 0.88
chr11_19302572_19302855 0.15 E2F8
 E2F transcription factor 8
 39546
 0.14
chr13_110780795_110780946 0.15 ENSG00000265885
 .
 30372
 0.24
chr6_143228096_143228637 0.15 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 37972
 0.2
chr11_134201877_134202251 0.15 GLB1L2
 galactosidase, beta 1-like 2
 108
 0.97
chr10_105211794_105212415 0.15 CALHM2
 calcium homeostasis modulator 2
 29
 0.88
chr6_31540520_31540671 0.15 LTA
 lymphotoxin alpha
 535
 0.44
chr19_872645_872938 0.15 CFD
 complement factor D (adipsin)
 13101
 0.07
chr17_55557828_55557979 0.15 RP11-118E18.2
43055
 0.16
chr17_27375692_27375843 0.15 PIPOX
 pipecolic acid oxidase
 4498
 0.14
chr21_44466329_44466480 0.15 CBS
 cystathionine-beta-synthase
 12647
 0.18
chr9_130738368_130738519 0.15 FAM102A
 family with sequence similarity 102, member A
 4349
 0.13
chr1_233430570_233431212 0.15 PCNXL2
 pecanex-like 2 (Drosophila)
 568
 0.83
chr11_1865337_1865488 0.15 TNNI2
 troponin I type 2 (skeletal, fast)
 3988
 0.11
chr7_153749645_153749898 0.15 DPP6
 dipeptidyl-peptidase 6
 6
 0.98
chr5_1793533_1793754 0.15 MRPL36
 mitochondrial ribosomal protein L36
 6221
 0.19
chr9_136004184_136004335 0.15 RALGDS
 ral guanine nucleotide dissociation stimulator
 529
 0.71
chr12_56732840_56732991 0.15 IL23A
 interleukin 23, alpha subunit p19
 252
 0.8
chr12_113906014_113906165 0.15 RP11-82C23.2
3719
 0.19
chrX_7061516_7061667 0.15 ENSG00000264268
 .
 4310
 0.26
chr10_3665379_3665530 0.14 RP11-184A2.3
127805
 0.06
chr10_30993356_30993652 0.14 SVILP1
 supervillin pseudogene 1
 8654
 0.27
chr17_47572677_47573321 0.14 NGFR
 nerve growth factor receptor
 344
 0.86
chr17_47819247_47819793 0.14 FAM117A
 family with sequence similarity 117, member A
 17631
 0.14
chr1_245851125_245851276 0.14 RP11-522M21.3
11420
 0.28
chr15_69652737_69652888 0.14 ENSG00000252972
 .
 7112
 0.13
chr2_85106634_85106918 0.14 TRABD2A
 TraB domain containing 2A
 1430
 0.42
chr19_47609844_47609995 0.14 SAE1
 SUMO1 activating enzyme subunit 1
 6612
 0.16
chr1_233749998_233750164 0.14 KCNK1
 potassium channel, subfamily K, member 1
 331
 0.91
chr17_4802078_4802229 0.14 C17orf107
 chromosome 17 open reading frame 107
 560
 0.5
chr1_9688741_9688898 0.14 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 22971
 0.15
chr5_150535420_150535844 0.14 ANXA6
 annexin A6
 1676
 0.39
chr1_7740584_7741157 0.14 CAMTA1
 calmodulin binding transcription activator 1
 55598
 0.13
chr2_97466776_97466927 0.14 ENSG00000264157
 .
 2836
 0.19
chr15_101143012_101143328 0.14 ASB7
 ankyrin repeat and SOCS box containing 7
 356
 0.69
chr1_227950100_227950251 0.14 SNAP47
 synaptosomal-associated protein, 47kDa
 14411
 0.16
chr14_91710752_91710947 0.14 GPR68
 G protein-coupled receptor 68
 3
 0.97
chr5_137802209_137802360 0.14 EGR1
 early growth response 1
 1105
 0.47
chr9_75142469_75142962 0.14 ENSG00000238402
 .
 563
 0.81
chr3_124553965_124554410 0.14 ITGB5
 integrin, beta 5
 6211
 0.23
chrX_75648113_75648326 0.14 MAGEE1
 melanoma antigen family E, 1
 173
 0.98
chr19_10397706_10398023 0.14 ICAM4
 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
 184
 0.83
chr19_3338800_3339014 0.14 NFIC
 nuclear factor I/C (CCAAT-binding transcription factor)
 20654
 0.16
chr10_104941185_104941336 0.14 NT5C2
 5'-nucleotidase, cytosolic II
 6521
 0.23
chr17_73716953_73717205 0.14 ITGB4
 integrin, beta 4
 329
 0.8
chr6_31540117_31540270 0.14 LTA
 lymphotoxin alpha
 133
 0.85
chr19_50063668_50063821 0.14 NOSIP
 nitric oxide synthase interacting protein
 143
 0.88
chr2_120934672_120935030 0.14 ENSG00000202046
 .
 14970
 0.19
chr9_102058986_102059155 0.14 ENSG00000222337
 .
 12766
 0.24
chr4_26270650_26270801 0.14 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
 3504
 0.38
chr7_55636821_55636978 0.14 VOPP1
 vesicular, overexpressed in cancer, prosurvival protein 1
 2662
 0.29
chr20_57739224_57739506 0.14 ZNF831
 zinc finger protein 831
 26710
 0.21
chr6_32605191_32605375 0.14 HLA-DQA1
 major histocompatibility complex, class II, DQ alpha 1
 86
 0.96
chr22_20194565_20194781 0.14 XXbac-B444P24.8
2232
 0.21
chr9_127633043_127633194 0.14 ARPC5L
 actin related protein 2/3 complex, subunit 5-like
 1634
 0.27
chr1_228676613_228676764 0.14 RNF187
 ring finger protein 187
 1926
 0.16
chr5_139494643_139494794 0.14 PURA
 purine-rich element binding protein A
 1010
 0.46
chr16_11145985_11146136 0.13 RP11-66H6.3
18899
 0.19
chr4_165304775_165304980 0.13 MARCH1
 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
 264
 0.96
chr10_24912096_24912247 0.13 ARHGAP21
 Rho GTPase activating protein 21
 408
 0.88
chr11_67234655_67234806 0.13 TMEM134
 transmembrane protein 134
 1974
 0.13
chr2_105478176_105478327 0.13 AC018730.4
5703
 0.14
chr6_47002361_47002718 0.13 GPR110
 G protein-coupled receptor 110
 7491
 0.28
chr5_146257138_146257401 0.13 PPP2R2B
 protein phosphatase 2, regulatory subunit B, beta
 936
 0.67
chr9_108319921_108320392 0.13 RP11-235C23.5
154
 0.64
chr16_74640764_74640944 0.13 GLG1
 golgi glycoprotein 1
 138
 0.97
chr17_53341326_53341539 0.13 HLF
 hepatic leukemia factor
 941
 0.65
chr17_3598807_3599359 0.13 P2RX5
 purinergic receptor P2X, ligand-gated ion channel, 5
 244
 0.86
chr4_90228457_90229530 0.13 GPRIN3
 GPRIN family member 3
 168
 0.97
chr2_136577729_136578391 0.13 AC011893.3
299
 0.89
chr9_95826666_95826817 0.13 SUSD3
 sushi domain containing 3
 4641
 0.2
chr5_137801416_137801666 0.13 EGR1
 early growth response 1
 362
 0.85
chr10_96996474_96996625 0.13 RP11-310E22.4
5648
 0.25
chr7_110724205_110724356 0.13 LRRN3
 leucine rich repeat neuronal 3
 6782
 0.27
chr7_26192093_26192429 0.13 NFE2L3
 nuclear factor, erythroid 2-like 3
 401
 0.85
chr17_28705982_28706205 0.13 CPD
 carboxypeptidase D
 170
 0.94
chr2_10522774_10523051 0.13 HPCAL1
 hippocalcin-like 1
 37235
 0.15
chr2_166650914_166651206 0.13 GALNT3
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
 100
 0.98
chr22_42177525_42177912 0.13 MEI1
 meiosis inhibitor 1
 21
 0.96
chr1_22383056_22383282 0.13 CDC42-IT1
 CDC42 intronic transcript 1 (non-protein coding)
 2521
 0.18
chr2_25473653_25473920 0.13 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
 1394
 0.47

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of MYF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0072110 glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.1 GO:1901722 regulation of cell proliferation involved in kidney development(GO:1901722)
0.1 0.3 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.1 GO:0014056 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.2 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.2 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:0090192 regulation of glomerulus development(GO:0090192)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0032202 telomere assembly(GO:0032202)
0.0 0.1 GO:0003170 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:2000188 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.0 GO:0090281 negative regulation of calcium ion import(GO:0090281)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0002327 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0032462 regulation of protein homooligomerization(GO:0032462)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0002902 regulation of B cell apoptotic process(GO:0002902)
0.0 0.0 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.0 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.0 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:1903301 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.0 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.1 GO:0045061 thymic T cell selection(GO:0045061)
0.0 0.0 GO:0051608 histamine transport(GO:0051608)
0.0 0.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.0 GO:0009912 auditory receptor cell fate commitment(GO:0009912) auditory receptor cell fate determination(GO:0042668) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.0 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.0 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.1 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.0 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.0 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0 0.1 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.0 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.0 GO:0032928 regulation of superoxide anion generation(GO:0032928) regulation of superoxide metabolic process(GO:0090322)
0.0 0.0 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.0 GO:0021702 cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.0 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.0 GO:0061316 negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) canonical Wnt signaling pathway involved in heart development(GO:0061316) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.3 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.0 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.0 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.0 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)