Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NANOG

Z-value: 1.23

Motif logo

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Transcription factors associated with NANOG

Gene Symbol Gene ID Gene Info
ENSG00000111704.6 NANOG

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NANOGchr12_7945798_794594936620.1361750.801.0e-02Click!

Activity of the NANOG motif across conditions

Conditions sorted by the z-value of the NANOG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_114180362_114180910 0.82 MARCKS
myristoylated alanine-rich protein kinase C substrate
2095
0.32
chr16_2174847_2175247 0.70 RP11-304L19.2

5839
0.06
chr7_27212262_27212557 0.66 HOXA10
homeobox A10
1516
0.14
chr19_6076963_6077580 0.57 CTC-232P5.3

9307
0.15
chr8_104153660_104153959 0.57 C8orf56
chromosome 8 open reading frame 56
106
0.89
chr10_49812568_49813319 0.55 ARHGAP22
Rho GTPase activating protein 22
54
0.98
chr17_55980324_55980725 0.53 CUEDC1
CUE domain containing 1
226
0.93
chr2_60779607_60780575 0.52 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
449
0.87
chr19_33784339_33784950 0.49 CTD-2540B15.11

6196
0.14
chr4_16900577_16901013 0.46 LDB2
LIM domain binding 2
363
0.93
chr11_121800761_121801203 0.45 ENSG00000252556
.
74081
0.11
chr19_46916092_46916684 0.44 CCDC8
coiled-coil domain containing 8
453
0.75
chr8_18871547_18872047 0.43 PSD3
pleckstrin and Sec7 domain containing 3
601
0.78
chr8_142141679_142142152 0.43 RP11-809O17.1

1855
0.33
chr15_40626168_40626616 0.43 ENSG00000252714
.
2543
0.12
chr7_128337244_128337509 0.43 ENSG00000201041
.
117
0.79
chr7_30199428_30199624 0.42 AC007036.5

2379
0.26
chr2_142888867_142889088 0.41 LRP1B
low density lipoprotein receptor-related protein 1B
293
0.93
chr7_100776904_100777303 0.41 SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
6724
0.11
chr1_209381259_209381734 0.41 ENSG00000230937
.
223982
0.02
chr2_225775342_225775493 0.40 DOCK10
dedicator of cytokinesis 10
36365
0.23
chr8_62624685_62625179 0.40 ASPH
aspartate beta-hydroxylase
2152
0.32
chr11_120083079_120083522 0.39 OAF
OAF homolog (Drosophila)
1291
0.42
chr5_77943226_77943942 0.38 LHFPL2
lipoma HMGIC fusion partner-like 2
1064
0.69
chr4_16899723_16900066 0.38 LDB2
LIM domain binding 2
291
0.95
chr11_92499156_92499668 0.38 RP11-203F8.1

621
0.79
chr4_159092030_159092251 0.36 RP11-597D13.9

236
0.78
chr4_30718989_30719310 0.36 PCDH7
protocadherin 7
2888
0.4
chr3_185463378_185463630 0.36 ENSG00000265470
.
22188
0.19
chr5_108992370_108992546 0.36 ENSG00000266090
.
28823
0.18
chr20_47897294_47897664 0.35 ENSG00000212304
.
259
0.71
chr10_49893410_49893567 0.34 WDFY4
WDFY family member 4
567
0.8
chr3_13040834_13041042 0.34 IQSEC1
IQ motif and Sec7 domain 1
12402
0.27
chr14_23504597_23504748 0.33 PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
233
0.81
chr9_128170108_128170336 0.33 MAPKAP1
mitogen-activated protein kinase associated protein 1
76558
0.09
chr21_43882491_43882642 0.33 SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
33562
0.1
chr5_158444877_158445028 0.33 CTD-2363C16.2

32138
0.18
chr11_118079199_118079350 0.32 AMICA1
adhesion molecule, interacts with CXADR antigen 1
4326
0.17
chr11_69258827_69259069 0.32 CCND1
cyclin D1
196907
0.02
chr3_29554516_29555025 0.32 RBMS3-AS2
RBMS3 antisense RNA 2
103776
0.08
chr10_60273912_60274168 0.32 BICC1
bicaudal C homolog 1 (Drosophila)
1140
0.65
chr5_149534173_149534381 0.32 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
913
0.52
chr7_67384045_67384316 0.32 ENSG00000265600
.
562513
0.0
chr9_111578370_111578673 0.32 ACTL7B
actin-like 7B
40718
0.16
chr20_47340203_47340354 0.31 ENSG00000251876
.
15707
0.28
chr4_144280055_144280346 0.31 ENSG00000265623
.
15587
0.2
chr12_123215443_123215626 0.31 HCAR1
hydroxycarboxylic acid receptor 1
144
0.94
chr1_121271248_121271399 0.31 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
335386
0.01
chr7_65746937_65747265 0.31 TPST1
tyrosylprotein sulfotransferase 1
60510
0.11
chr16_4993031_4993210 0.31 PPL
periplakin
5984
0.15
chr22_24862876_24863027 0.31 UPB1
ureidopropionase, beta
255
0.91
chr15_68564352_68564564 0.31 FEM1B
fem-1 homolog b (C. elegans)
5683
0.19
chr13_103478539_103479046 0.31 ENSG00000222301
.
6449
0.13
chr1_86036403_86036586 0.31 DDAH1
dimethylarginine dimethylaminohydrolase 1
7439
0.2
chr4_81187181_81187534 0.31 FGF5
fibroblast growth factor 5
396
0.89
chr12_121136486_121136637 0.30 RP11-173P15.3

743
0.49
chr7_23507689_23508280 0.30 IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
2102
0.28
chr4_173708323_173708474 0.30 ENSG00000241652
.
354396
0.01
chr12_32740907_32741058 0.30 FGD4
FYVE, RhoGEF and PH domain containing 4
10478
0.26
chr9_124725889_124726074 0.30 TTLL11
tubulin tyrosine ligase-like family, member 11
129904
0.04
chr7_100464814_100466140 0.29 TRIP6
thyroid hormone receptor interactor 6
717
0.47
chr14_24783731_24783882 0.29 LTB4R
leukotriene B4 receptor
100
0.9
chr19_7159886_7160037 0.29 ENSG00000266483
.
545
0.75
chr3_134369662_134369917 0.29 KY
kyphoscoliosis peptidase
71
0.98
chr5_71768722_71768873 0.29 RP11-389C8.2

30583
0.19
chr18_59001001_59001554 0.29 CDH20
cadherin 20, type 2
229
0.96
chr11_61594474_61594781 0.29 FADS2
fatty acid desaturase 2
237
0.86
chr8_116463616_116464117 0.29 TRPS1
trichorhinophalangeal syndrome I
40582
0.2
chr14_64664030_64664199 0.28 SYNE2
spectrin repeat containing, nuclear envelope 2
4797
0.28
chr14_91797432_91797583 0.28 ENSG00000265856
.
2550
0.31
chr3_138581962_138582285 0.28 PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
28343
0.2
chr6_7202628_7202802 0.28 ENSG00000201483
.
14796
0.19
chr10_13746137_13746452 0.28 ENSG00000222235
.
684
0.58
chr22_45630973_45631282 0.28 KIAA0930
KIAA0930
1031
0.52
chr8_132828485_132828822 0.28 EFR3A
EFR3 homolog A (S. cerevisiae)
87682
0.1
chr14_101292536_101293492 0.28 AL117190.2

2523
0.08
chr12_10902635_10902853 0.27 YBX3
Y box binding protein 3
26833
0.13
chr9_13278250_13278433 0.27 RP11-272P10.2

845
0.51
chr9_94065254_94065575 0.27 AUH
AU RNA binding protein/enoyl-CoA hydratase
58763
0.16
chr7_70201396_70202343 0.27 AUTS2
autism susceptibility candidate 2
7744
0.34
chr15_89686892_89687043 0.27 ENSG00000239151
.
22957
0.16
chr17_21279729_21280949 0.27 KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
830
0.69
chr12_132313238_132313523 0.27 MMP17
matrix metallopeptidase 17 (membrane-inserted)
295
0.89
chr5_83678519_83678875 0.26 EDIL3
EGF-like repeats and discoidin I-like domains 3
1507
0.37
chr11_1777334_1777604 0.26 CTSD
cathepsin D
1293
0.24
chr1_21649315_21649466 0.26 ECE1
endothelin converting enzyme 1
22607
0.18
chr3_114405799_114405950 0.26 ENSG00000264623
.
56498
0.15
chr15_94830020_94830171 0.26 MCTP2
multiple C2 domains, transmembrane 2
11335
0.32
chr19_55684291_55685412 0.26 SYT5
synaptotagmin V
1083
0.28
chr18_77551387_77551694 0.26 KCNG2
potassium voltage-gated channel, subfamily G, member 2
72128
0.1
chr16_54969072_54969449 0.26 IRX5
iroquois homeobox 5
3276
0.4
chr9_95297440_95297591 0.26 ECM2
extracellular matrix protein 2, female organ and adipocyte specific
739
0.65
chr2_180726238_180726902 0.26 ZNF385B
zinc finger protein 385B
338
0.8
chr1_44513542_44514157 0.26 SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
16715
0.14
chr8_29685440_29685777 0.26 ENSG00000221003
.
100513
0.07
chr1_8918227_8918467 0.26 ENO1-IT1
ENO1 intronic transcript 1 (non-protein coding)
19719
0.12
chr2_36585229_36585663 0.25 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
1832
0.5
chr5_95562456_95562808 0.25 ENSG00000206997
.
16701
0.27
chr14_52707563_52708006 0.25 PTGDR
prostaglandin D2 receptor (DP)
26647
0.22
chr21_37305025_37305176 0.25 FKSG68

34373
0.16
chr15_90580732_90580981 0.25 ZNF710
zinc finger protein 710
30390
0.11
chr5_33892545_33892868 0.25 ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
409
0.85
chr6_152085810_152086045 0.25 ESR1
estrogen receptor 1
39639
0.18
chr7_81405901_81406052 0.25 HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
6222
0.33
chr1_172352648_172352805 0.25 DNM3
dynamin 3
4568
0.19
chr18_46460407_46461027 0.25 SMAD7
SMAD family member 7
14158
0.24
chr10_123922760_123923208 0.25 TACC2
transforming, acidic coiled-coil containing protein 2
43
0.99
chr11_111412763_111412914 0.24 LAYN
layilin
561
0.64
chr17_60781005_60781559 0.24 RP11-156L14.1

2285
0.25
chr1_31971829_31971980 0.24 ENSG00000206981
.
1379
0.42
chr7_27182401_27182640 0.24 HOXA5
homeobox A5
767
0.32
chr11_16023597_16024065 0.24 CTD-3096P4.1

20905
0.28
chr17_2658644_2658831 0.24 ENSG00000265566
.
1611
0.28
chr6_113198454_113198633 0.24 ENSG00000201386
.
94152
0.09
chr3_188841606_188841757 0.24 TPRG1
tumor protein p63 regulated 1
23771
0.27
chr20_48600008_48600312 0.24 SNAI1
snail family zinc finger 1
624
0.68
chr18_42169569_42169984 0.24 SETBP1
SET binding protein 1
90362
0.1
chr16_85783565_85784591 0.23 C16orf74
chromosome 16 open reading frame 74
479
0.7
chr10_16992831_16993197 0.23 CUBN
cubilin (intrinsic factor-cobalamin receptor)
33180
0.22
chr12_117036919_117037510 0.23 MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
23558
0.24
chr16_3095827_3096553 0.23 MMP25
matrix metallopeptidase 25
492
0.51
chrX_117973061_117973360 0.23 ZCCHC12
zinc finger, CCHC domain containing 12
15457
0.24
chr19_10736478_10736985 0.23 SLC44A2
solute carrier family 44 (choline transporter), member 2
530
0.65
chr11_65790225_65790471 0.23 CATSPER1
cation channel, sperm associated 1
3640
0.11
chr3_21792365_21792565 0.23 ZNF385D
zinc finger protein 385D
462
0.89
chr19_51964655_51964830 0.23 SIGLEC8
sialic acid binding Ig-like lectin 8
3032
0.13
chr11_46004459_46004616 0.23 PHF21A
PHD finger protein 21A
37117
0.13
chr2_45228184_45228926 0.23 SIX2
SIX homeobox 2
8014
0.26
chr22_43327364_43327528 0.23 PACSIN2
protein kinase C and casein kinase substrate in neurons 2
14433
0.22
chr10_30092784_30093253 0.23 SVIL
supervillin
68285
0.12
chr1_56942848_56943117 0.23 ENSG00000223307
.
99892
0.08
chr6_49293859_49294324 0.23 ENSG00000252457
.
18430
0.26
chr9_118917055_118917469 0.23 PAPPA
pregnancy-associated plasma protein A, pappalysin 1
1179
0.59
chr2_86643247_86643503 0.23 KDM3A
lysine (K)-specific demethylase 3A
24395
0.16
chr1_72749537_72750410 0.23 NEGR1
neuronal growth regulator 1
1556
0.58
chr3_188139297_188139660 0.22 LPP-AS1
LPP antisense RNA 1
146976
0.04
chr6_11044848_11045055 0.22 ELOVL2-AS1
ELOVL2 antisense RNA 1
25
0.87
chr15_81377697_81377848 0.22 C15orf26
chromosome 15 open reading frame 26
13977
0.22
chr2_220394806_220394967 0.22 CHPF
chondroitin polymerizing factor
12933
0.07
chr4_73185764_73186042 0.22 RP11-373J21.1

2842
0.42
chr15_71184312_71185443 0.22 LRRC49
leucine rich repeat containing 49
88
0.55
chr11_73024866_73025155 0.22 ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
2400
0.21
chr5_178980827_178981020 0.22 RUFY1
RUN and FYVE domain containing 1
3084
0.24
chr8_128771730_128771923 0.22 MYC
v-myc avian myelocytomatosis viral oncogene homolog
23349
0.22
chr1_114311936_114312108 0.22 PHTF1
putative homeodomain transcription factor 1
9924
0.19
chr5_42719011_42719269 0.22 CCDC152
coiled-coil domain containing 152
37763
0.19
chr19_11433197_11433348 0.22 CTC-510F12.6

440
0.67
chr9_124048192_124048723 0.22 GSN
gelsolin
413
0.59
chr10_134349773_134350081 0.21 INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
1397
0.46
chr6_14671214_14671445 0.21 ENSG00000206960
.
24563
0.28
chr5_83017716_83018280 0.21 HAPLN1
hyaluronan and proteoglycan link protein 1
566
0.78
chr10_102278895_102279852 0.21 SEC31B
SEC31 homolog B (S. cerevisiae)
218
0.92
chr10_17074110_17074261 0.21 CUBN
cubilin (intrinsic factor-cobalamin receptor)
47991
0.17
chr11_109966416_109966567 0.21 ZC3H12C
zinc finger CCCH-type containing 12C
2404
0.45
chr8_145925356_145925968 0.21 AF186192.5

5257
0.15
chr12_79916269_79916420 0.21 ENSG00000243714
.
2606
0.3
chr21_39862457_39862608 0.21 ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
7813
0.32
chr10_65460212_65460378 0.21 REEP3
receptor accessory protein 3
179172
0.03
chr9_134614958_134615256 0.21 RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
224
0.94
chr5_14154391_14154790 0.21 TRIO
trio Rho guanine nucleotide exchange factor
10761
0.32
chr22_33197948_33198143 0.21 TIMP3
TIMP metallopeptidase inhibitor 3
358
0.9
chr11_86319379_86319598 0.21 ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
48626
0.18
chr19_16178450_16178920 0.21 TPM4
tropomyosin 4
175
0.95
chr17_74543145_74543365 0.21 RP11-666A8.7

2778
0.11
chr6_157020523_157020674 0.20 ARID1B
AT rich interactive domain 1B (SWI1-like)
78465
0.1
chr12_122884907_122885085 0.20 CLIP1
CAP-GLY domain containing linker protein 1
435
0.86
chr19_16936008_16936179 0.20 SIN3B
SIN3 transcription regulator family member B
4118
0.16
chr12_123713391_123713550 0.20 MPHOSPH9
M-phase phosphoprotein 9
1523
0.29
chr4_90674612_90674925 0.20 RP11-115D19.1

72105
0.11
chr12_6657091_6657293 0.20 IFFO1
intermediate filament family orphan 1
3874
0.09
chr7_143078673_143079796 0.20 ZYX
zyxin
234
0.85
chr22_27695536_27695687 0.20 ENSG00000200443
.
263761
0.02
chr8_56832215_56832446 0.20 ENSG00000216204
.
10810
0.14
chr10_17277189_17277453 0.20 RP11-124N14.3

489
0.76
chr2_64837127_64837278 0.20 ENSG00000252414
.
31176
0.17
chr9_96231273_96231424 0.20 FAM120AOS
family with sequence similarity 120A opposite strand
15474
0.14
chr8_28912831_28912982 0.20 CTD-2647L4.4

546
0.71
chr15_74212019_74212306 0.20 LOXL1-AS1
LOXL1 antisense RNA 1
49
0.97
chr3_139258322_139258643 0.20 RBP1
retinol binding protein 1, cellular
79
0.75
chr9_33081206_33081450 0.20 SMU1
smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
4663
0.19
chr1_182931948_182932121 0.20 ENSG00000264768
.
3324
0.2
chr22_24541736_24541961 0.20 CABIN1
calcineurin binding protein 1
9958
0.17
chr20_57458028_57458245 0.20 ENSG00000225806
.
5711
0.14
chr7_23514162_23514615 0.20 IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
4302
0.2
chr7_37723352_37723576 0.20 GPR141
G protein-coupled receptor 141
11
0.5
chr6_169471024_169471293 0.19 XXyac-YX65C7_A.2

142191
0.05
chr4_14113589_14113913 0.19 ENSG00000252092
.
453500
0.01
chr5_111090218_111090459 0.19 NREP
neuronal regeneration related protein
1610
0.42
chr7_134512305_134512501 0.19 CALD1
caldesmon 1
16232
0.27
chr22_38173266_38173417 0.19 ENSG00000238569
.
8192
0.11
chr12_109246535_109246783 0.19 SSH1
slingshot protein phosphatase 1
4700
0.17
chr1_209958694_209958845 0.19 C1orf74
chromosome 1 open reading frame 74
865
0.47
chr10_126106510_126107495 0.19 OAT
ornithine aminotransferase
503
0.8
chr16_54689333_54689511 0.19 ENSG00000264079
.
106114
0.08
chr9_38026581_38026893 0.19 SHB
Src homology 2 domain containing adaptor protein B
42471
0.17
chr2_106014491_106015411 0.19 FHL2
four and a half LIM domains 2
556
0.78
chr4_91049201_91049889 0.19 CCSER1
coiled-coil serine-rich protein 1
809
0.78
chr4_170190845_170191352 0.19 SH3RF1
SH3 domain containing ring finger 1
10
0.99
chr2_113997514_113997878 0.19 RP11-65I12.1

611
0.6
chr16_476332_477479 0.19 RAB11FIP3
RAB11 family interacting protein 3 (class II)
526
0.62

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NANOG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.1 0.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.3 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0033604 negative regulation of catecholamine secretion(GO:0033604)
0.0 0.1 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0072191 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.2 GO:0036296 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.1 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0009650 UV protection(GO:0009650)
0.0 0.0 GO:1902339 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0034442 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0072077 mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003337) renal vesicle morphogenesis(GO:0072077) metanephric renal vesicle morphogenesis(GO:0072283)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.2 GO:0032770 positive regulation of monooxygenase activity(GO:0032770)
0.0 0.0 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.0 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:0035930 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.0 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.0 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0099518 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.1 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.0 GO:0043259 laminin-10 complex(GO:0043259)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins