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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for NANOG

Z-value: 1.23

Motif logo

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Transcription factors associated with NANOG

Gene Symbol Gene ID Gene Info
NANOG
ENSG00000111704.6 Nanog homeobox

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_7945798_7945949NANOG36620.1361750.801.0e-02Click!

Activity of the NANOG motif across conditions

Conditions sorted by the z-value of the NANOG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_114180362_114180910 0.82 MARCKS
 myristoylated alanine-rich protein kinase C substrate
 2095
 0.32
chr16_2174847_2175247 0.70 RP11-304L19.2
5839
 0.06
chr7_27212262_27212557 0.66 HOXA10
 homeobox A10
 1516
 0.14
chr19_6076963_6077580 0.57 CTC-232P5.3
9307
 0.15
chr8_104153660_104153959 0.57 C8orf56
 chromosome 8 open reading frame 56
 106
 0.89
chr10_49812568_49813319 0.55 ARHGAP22
 Rho GTPase activating protein 22
 54
 0.98
chr17_55980324_55980725 0.53 CUEDC1
 CUE domain containing 1
 226
 0.93
chr2_60779607_60780575 0.52 BCL11A
 B-cell CLL/lymphoma 11A (zinc finger protein)
 449
 0.87
chr19_33784339_33784950 0.49 CTD-2540B15.11
6196
 0.14
chr4_16900577_16901013 0.46 LDB2
 LIM domain binding 2
 363
 0.93
chr11_121800761_121801203 0.45 ENSG00000252556
 .
 74081
 0.11
chr19_46916092_46916684 0.44 CCDC8
 coiled-coil domain containing 8
 453
 0.75
chr8_18871547_18872047 0.43 PSD3
 pleckstrin and Sec7 domain containing 3
 601
 0.78
chr8_142141679_142142152 0.43 RP11-809O17.1
1855
 0.33
chr15_40626168_40626616 0.43 ENSG00000252714
 .
 2543
 0.12
chr7_128337244_128337509 0.43 ENSG00000201041
 .
 117
 0.79
chr7_30199428_30199624 0.42 AC007036.5
2379
 0.26
chr2_142888867_142889088 0.41 LRP1B
 low density lipoprotein receptor-related protein 1B
 293
 0.93
chr7_100776904_100777303 0.41 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
 6724
 0.11
chr1_209381259_209381734 0.41 ENSG00000230937
 .
 223982
 0.02
chr2_225775342_225775493 0.40 DOCK10
 dedicator of cytokinesis 10
 36365
 0.23
chr8_62624685_62625179 0.40 ASPH
 aspartate beta-hydroxylase
 2152
 0.32
chr11_120083079_120083522 0.39 OAF
 OAF homolog (Drosophila)
 1291
 0.42
chr5_77943226_77943942 0.38 LHFPL2
 lipoma HMGIC fusion partner-like 2
 1064
 0.69
chr4_16899723_16900066 0.38 LDB2
 LIM domain binding 2
 291
 0.95
chr11_92499156_92499668 0.38 RP11-203F8.1
621
 0.79
chr4_159092030_159092251 0.36 RP11-597D13.9
236
 0.78
chr4_30718989_30719310 0.36 PCDH7
 protocadherin 7
 2888
 0.4
chr3_185463378_185463630 0.36 ENSG00000265470
 .
 22188
 0.19
chr5_108992370_108992546 0.36 ENSG00000266090
 .
 28823
 0.18
chr20_47897294_47897664 0.35 ENSG00000212304
 .
 259
 0.71
chr10_49893410_49893567 0.34 WDFY4
 WDFY family member 4
 567
 0.8
chr3_13040834_13041042 0.34 IQSEC1
 IQ motif and Sec7 domain 1
 12402
 0.27
chr14_23504597_23504748 0.33 PSMB5
 proteasome (prosome, macropain) subunit, beta type, 5
 233
 0.81
chr9_128170108_128170336 0.33 MAPKAP1
 mitogen-activated protein kinase associated protein 1
 76558
 0.09
chr21_43882491_43882642 0.33 SLC37A1
 solute carrier family 37 (glucose-6-phosphate transporter), member 1
 33562
 0.1
chr5_158444877_158445028 0.33 CTD-2363C16.2
32138
 0.18
chr11_118079199_118079350 0.32 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 4326
 0.17
chr11_69258827_69259069 0.32 CCND1
 cyclin D1
 196907
 0.02
chr3_29554516_29555025 0.32 RBMS3-AS2
 RBMS3 antisense RNA 2
 103776
 0.08
chr10_60273912_60274168 0.32 BICC1
 bicaudal C homolog 1 (Drosophila)
 1140
 0.65
chr5_149534173_149534381 0.32 PDGFRB
 platelet-derived growth factor receptor, beta polypeptide
 913
 0.52
chr7_67384045_67384316 0.32 ENSG00000265600
 .
 562513
 0.0
chr9_111578370_111578673 0.32 ACTL7B
 actin-like 7B
 40718
 0.16
chr20_47340203_47340354 0.31 ENSG00000251876
 .
 15707
 0.28
chr4_144280055_144280346 0.31 ENSG00000265623
 .
 15587
 0.2
chr12_123215443_123215626 0.31 HCAR1
 hydroxycarboxylic acid receptor 1
 144
 0.94
chr1_121271248_121271399 0.31 FCGR1B
 Fc fragment of IgG, high affinity Ib, receptor (CD64)
 335386
 0.01
chr7_65746937_65747265 0.31 TPST1
 tyrosylprotein sulfotransferase 1
 60510
 0.11
chr16_4993031_4993210 0.31 PPL
 periplakin
 5984
 0.15
chr22_24862876_24863027 0.31 UPB1
 ureidopropionase, beta
 255
 0.91
chr15_68564352_68564564 0.31 FEM1B
 fem-1 homolog b (C. elegans)
 5683
 0.19
chr13_103478539_103479046 0.31 ENSG00000222301
 .
 6449
 0.13
chr1_86036403_86036586 0.31 DDAH1
 dimethylarginine dimethylaminohydrolase 1
 7439
 0.2
chr4_81187181_81187534 0.31 FGF5
 fibroblast growth factor 5
 396
 0.89
chr12_121136486_121136637 0.30 RP11-173P15.3
743
 0.49
chr7_23507689_23508280 0.30 IGF2BP3
 insulin-like growth factor 2 mRNA binding protein 3
 2102
 0.28
chr4_173708323_173708474 0.30 ENSG00000241652
 .
 354396
 0.01
chr12_32740907_32741058 0.30 FGD4
 FYVE, RhoGEF and PH domain containing 4
 10478
 0.26
chr9_124725889_124726074 0.30 TTLL11
 tubulin tyrosine ligase-like family, member 11
 129904
 0.04
chr7_100464814_100466140 0.29 TRIP6
 thyroid hormone receptor interactor 6
 717
 0.47
chr14_24783731_24783882 0.29 LTB4R
 leukotriene B4 receptor
 100
 0.9
chr19_7159886_7160037 0.29 ENSG00000266483
 .
 545
 0.75
chr3_134369662_134369917 0.29 KY
 kyphoscoliosis peptidase
 71
 0.98
chr5_71768722_71768873 0.29 RP11-389C8.2
30583
 0.19
chr18_59001001_59001554 0.29 CDH20
 cadherin 20, type 2
 229
 0.96
chr11_61594474_61594781 0.29 FADS2
 fatty acid desaturase 2
 237
 0.86
chr8_116463616_116464117 0.29 TRPS1
 trichorhinophalangeal syndrome I
 40582
 0.2
chr14_64664030_64664199 0.28 SYNE2
 spectrin repeat containing, nuclear envelope 2
 4797
 0.28
chr14_91797432_91797583 0.28 ENSG00000265856
 .
 2550
 0.31
chr3_138581962_138582285 0.28 PIK3CB
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
 28343
 0.2
chr6_7202628_7202802 0.28 ENSG00000201483
 .
 14796
 0.19
chr10_13746137_13746452 0.28 ENSG00000222235
 .
 684
 0.58
chr22_45630973_45631282 0.28 KIAA0930
 KIAA0930
 1031
 0.52
chr8_132828485_132828822 0.28 EFR3A
 EFR3 homolog A (S. cerevisiae)
 87682
 0.1
chr14_101292536_101293492 0.28 AL117190.2
2523
 0.08
chr12_10902635_10902853 0.27 YBX3
 Y box binding protein 3
 26833
 0.13
chr9_13278250_13278433 0.27 RP11-272P10.2
845
 0.51
chr9_94065254_94065575 0.27 AUH
 AU RNA binding protein/enoyl-CoA hydratase
 58763
 0.16
chr7_70201396_70202343 0.27 AUTS2
 autism susceptibility candidate 2
 7744
 0.34
chr15_89686892_89687043 0.27 ENSG00000239151
 .
 22957
 0.16
chr17_21279729_21280949 0.27 KCNJ12
 potassium inwardly-rectifying channel, subfamily J, member 12
 830
 0.69
chr12_132313238_132313523 0.27 MMP17
 matrix metallopeptidase 17 (membrane-inserted)
 295
 0.89
chr5_83678519_83678875 0.26 EDIL3
 EGF-like repeats and discoidin I-like domains 3
 1507
 0.37
chr11_1777334_1777604 0.26 CTSD
 cathepsin D
 1293
 0.24
chr1_21649315_21649466 0.26 ECE1
 endothelin converting enzyme 1
 22607
 0.18
chr3_114405799_114405950 0.26 ENSG00000264623
 .
 56498
 0.15
chr15_94830020_94830171 0.26 MCTP2
 multiple C2 domains, transmembrane 2
 11335
 0.32
chr19_55684291_55685412 0.26 SYT5
 synaptotagmin V
 1083
 0.28
chr18_77551387_77551694 0.26 KCNG2
 potassium voltage-gated channel, subfamily G, member 2
 72128
 0.1
chr16_54969072_54969449 0.26 IRX5
 iroquois homeobox 5
 3276
 0.4
chr9_95297440_95297591 0.26 ECM2
 extracellular matrix protein 2, female organ and adipocyte specific
 739
 0.65
chr2_180726238_180726902 0.26 ZNF385B
 zinc finger protein 385B
 338
 0.8
chr1_44513542_44514157 0.26 SLC6A9
 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
 16715
 0.14
chr8_29685440_29685777 0.26 ENSG00000221003
 .
 100513
 0.07
chr1_8918227_8918467 0.26 ENO1-IT1
 ENO1 intronic transcript 1 (non-protein coding)
 19719
 0.12
chr2_36585229_36585663 0.25 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 1832
 0.5
chr5_95562456_95562808 0.25 ENSG00000206997
 .
 16701
 0.27
chr14_52707563_52708006 0.25 PTGDR
 prostaglandin D2 receptor (DP)
 26647
 0.22
chr21_37305025_37305176 0.25 FKSG68
34373
 0.16
chr15_90580732_90580981 0.25 ZNF710
 zinc finger protein 710
 30390
 0.11
chr5_33892545_33892868 0.25 ADAMTS12
 ADAM metallopeptidase with thrombospondin type 1 motif, 12
 409
 0.85
chr6_152085810_152086045 0.25 ESR1
 estrogen receptor 1
 39639
 0.18
chr7_81405901_81406052 0.25 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
 6222
 0.33
chr1_172352648_172352805 0.25 DNM3
 dynamin 3
 4568
 0.19
chr18_46460407_46461027 0.25 SMAD7
 SMAD family member 7
 14158
 0.24
chr10_123922760_123923208 0.25 TACC2
 transforming, acidic coiled-coil containing protein 2
 43
 0.99
chr11_111412763_111412914 0.24 LAYN
 layilin
 561
 0.64
chr17_60781005_60781559 0.24 RP11-156L14.1
2285
 0.25
chr1_31971829_31971980 0.24 ENSG00000206981
 .
 1379
 0.42
chr7_27182401_27182640 0.24 HOXA5
 homeobox A5
 767
 0.32
chr11_16023597_16024065 0.24 CTD-3096P4.1
20905
 0.28
chr17_2658644_2658831 0.24 ENSG00000265566
 .
 1611
 0.28
chr6_113198454_113198633 0.24 ENSG00000201386
 .
 94152
 0.09
chr3_188841606_188841757 0.24 TPRG1
 tumor protein p63 regulated 1
 23771
 0.27
chr20_48600008_48600312 0.24 SNAI1
 snail family zinc finger 1
 624
 0.68
chr18_42169569_42169984 0.24 SETBP1
 SET binding protein 1
 90362
 0.1
chr16_85783565_85784591 0.23 C16orf74
 chromosome 16 open reading frame 74
 479
 0.7
chr10_16992831_16993197 0.23 CUBN
 cubilin (intrinsic factor-cobalamin receptor)
 33180
 0.22
chr12_117036919_117037510 0.23 MAP1LC3B2
 microtubule-associated protein 1 light chain 3 beta 2
 23558
 0.24
chr16_3095827_3096553 0.23 MMP25
 matrix metallopeptidase 25
 492
 0.51
chrX_117973061_117973360 0.23 ZCCHC12
 zinc finger, CCHC domain containing 12
 15457
 0.24
chr19_10736478_10736985 0.23 SLC44A2
 solute carrier family 44 (choline transporter), member 2
 530
 0.65
chr11_65790225_65790471 0.23 CATSPER1
 cation channel, sperm associated 1
 3640
 0.11
chr3_21792365_21792565 0.23 ZNF385D
 zinc finger protein 385D
 462
 0.89
chr19_51964655_51964830 0.23 SIGLEC8
 sialic acid binding Ig-like lectin 8
 3032
 0.13
chr11_46004459_46004616 0.23 PHF21A
 PHD finger protein 21A
 37117
 0.13
chr2_45228184_45228926 0.23 SIX2
 SIX homeobox 2
 8014
 0.26
chr22_43327364_43327528 0.23 PACSIN2
 protein kinase C and casein kinase substrate in neurons 2
 14433
 0.22
chr10_30092784_30093253 0.23 SVIL
 supervillin
 68285
 0.12
chr1_56942848_56943117 0.23 ENSG00000223307
 .
 99892
 0.08
chr6_49293859_49294324 0.23 ENSG00000252457
 .
 18430
 0.26
chr9_118917055_118917469 0.23 PAPPA
 pregnancy-associated plasma protein A, pappalysin 1
 1179
 0.59
chr2_86643247_86643503 0.23 KDM3A
 lysine (K)-specific demethylase 3A
 24395
 0.16
chr1_72749537_72750410 0.23 NEGR1
 neuronal growth regulator 1
 1556
 0.58
chr3_188139297_188139660 0.22 LPP-AS1
 LPP antisense RNA 1
 146976
 0.04
chr6_11044848_11045055 0.22 ELOVL2-AS1
 ELOVL2 antisense RNA 1
 25
 0.87
chr15_81377697_81377848 0.22 C15orf26
 chromosome 15 open reading frame 26
 13977
 0.22
chr2_220394806_220394967 0.22 CHPF
 chondroitin polymerizing factor
 12933
 0.07
chr4_73185764_73186042 0.22 RP11-373J21.1
2842
 0.42
chr15_71184312_71185443 0.22 LRRC49
 leucine rich repeat containing 49
 88
 0.55
chr11_73024866_73025155 0.22 ARHGEF17
 Rho guanine nucleotide exchange factor (GEF) 17
 2400
 0.21
chr5_178980827_178981020 0.22 RUFY1
 RUN and FYVE domain containing 1
 3084
 0.24
chr8_128771730_128771923 0.22 MYC
 v-myc avian myelocytomatosis viral oncogene homolog
 23349
 0.22
chr1_114311936_114312108 0.22 PHTF1
 putative homeodomain transcription factor 1
 9924
 0.19
chr5_42719011_42719269 0.22 CCDC152
 coiled-coil domain containing 152
 37763
 0.19
chr19_11433197_11433348 0.22 CTC-510F12.6
440
 0.67
chr9_124048192_124048723 0.22 GSN
 gelsolin
 413
 0.59
chr10_134349773_134350081 0.21 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 1397
 0.46
chr6_14671214_14671445 0.21 ENSG00000206960
 .
 24563
 0.28
chr5_83017716_83018280 0.21 HAPLN1
 hyaluronan and proteoglycan link protein 1
 566
 0.78
chr10_102278895_102279852 0.21 SEC31B
 SEC31 homolog B (S. cerevisiae)
 218
 0.92
chr10_17074110_17074261 0.21 CUBN
 cubilin (intrinsic factor-cobalamin receptor)
 47991
 0.17
chr11_109966416_109966567 0.21 ZC3H12C
 zinc finger CCCH-type containing 12C
 2404
 0.45
chr8_145925356_145925968 0.21 AF186192.5
5257
 0.15
chr12_79916269_79916420 0.21 ENSG00000243714
 .
 2606
 0.3
chr21_39862457_39862608 0.21 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
 7813
 0.32
chr10_65460212_65460378 0.21 REEP3
 receptor accessory protein 3
 179172
 0.03
chr9_134614958_134615256 0.21 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 224
 0.94
chr5_14154391_14154790 0.21 TRIO
 trio Rho guanine nucleotide exchange factor
 10761
 0.32
chr22_33197948_33198143 0.21 TIMP3
 TIMP metallopeptidase inhibitor 3
 358
 0.9
chr11_86319379_86319598 0.21 ME3
 malic enzyme 3, NADP(+)-dependent, mitochondrial
 48626
 0.18
chr19_16178450_16178920 0.21 TPM4
 tropomyosin 4
 175
 0.95
chr17_74543145_74543365 0.21 RP11-666A8.7
2778
 0.11
chr6_157020523_157020674 0.20 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 78465
 0.1
chr12_122884907_122885085 0.20 CLIP1
 CAP-GLY domain containing linker protein 1
 435
 0.86
chr19_16936008_16936179 0.20 SIN3B
 SIN3 transcription regulator family member B
 4118
 0.16
chr12_123713391_123713550 0.20 MPHOSPH9
 M-phase phosphoprotein 9
 1523
 0.29
chr4_90674612_90674925 0.20 RP11-115D19.1
72105
 0.11
chr12_6657091_6657293 0.20 IFFO1
 intermediate filament family orphan 1
 3874
 0.09
chr7_143078673_143079796 0.20 ZYX
 zyxin
 234
 0.85
chr22_27695536_27695687 0.20 ENSG00000200443
 .
 263761
 0.02
chr8_56832215_56832446 0.20 ENSG00000216204
 .
 10810
 0.14
chr10_17277189_17277453 0.20 RP11-124N14.3
489
 0.76
chr2_64837127_64837278 0.20 ENSG00000252414
 .
 31176
 0.17
chr9_96231273_96231424 0.20 FAM120AOS
 family with sequence similarity 120A opposite strand
 15474
 0.14
chr8_28912831_28912982 0.20 CTD-2647L4.4
546
 0.71
chr15_74212019_74212306 0.20 LOXL1-AS1
 LOXL1 antisense RNA 1
 49
 0.97
chr3_139258322_139258643 0.20 RBP1
 retinol binding protein 1, cellular
 79
 0.75
chr9_33081206_33081450 0.20 SMU1
 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
 4663
 0.19
chr1_182931948_182932121 0.20 ENSG00000264768
 .
 3324
 0.2
chr22_24541736_24541961 0.20 CABIN1
 calcineurin binding protein 1
 9958
 0.17
chr20_57458028_57458245 0.20 ENSG00000225806
 .
 5711
 0.14
chr7_23514162_23514615 0.20 IGF2BP3
 insulin-like growth factor 2 mRNA binding protein 3
 4302
 0.2
chr7_37723352_37723576 0.20 GPR141
 G protein-coupled receptor 141
 11
 0.5
chr6_169471024_169471293 0.19 XXyac-YX65C7_A.2
142191
 0.05
chr4_14113589_14113913 0.19 ENSG00000252092
 .
 453500
 0.01
chr5_111090218_111090459 0.19 NREP
 neuronal regeneration related protein
 1610
 0.42
chr7_134512305_134512501 0.19 CALD1
 caldesmon 1
 16232
 0.27
chr22_38173266_38173417 0.19 ENSG00000238569
 .
 8192
 0.11
chr12_109246535_109246783 0.19 SSH1
 slingshot protein phosphatase 1
 4700
 0.17
chr1_209958694_209958845 0.19 C1orf74
 chromosome 1 open reading frame 74
 865
 0.47
chr10_126106510_126107495 0.19 OAT
 ornithine aminotransferase
 503
 0.8
chr16_54689333_54689511 0.19 ENSG00000264079
 .
 106114
 0.08
chr9_38026581_38026893 0.19 SHB
 Src homology 2 domain containing adaptor protein B
 42471
 0.17
chr2_106014491_106015411 0.19 FHL2
 four and a half LIM domains 2
 556
 0.78
chr4_91049201_91049889 0.19 CCSER1
 coiled-coil serine-rich protein 1
 809
 0.78
chr4_170190845_170191352 0.19 SH3RF1
 SH3 domain containing ring finger 1
 10
 0.99
chr2_113997514_113997878 0.19 RP11-65I12.1
611
 0.6
chr16_476332_477479 0.19 RAB11FIP3
 RAB11 family interacting protein 3 (class II)
 526
 0.62

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of NANOG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.1 0.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.3 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0033604 negative regulation of catecholamine secretion(GO:0033604)
0.0 0.1 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0072191 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.2 GO:0036296 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.1 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0009650 UV protection(GO:0009650)
0.0 0.0 GO:1902339 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0034442 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0072077 mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003337) renal vesicle morphogenesis(GO:0072077) metanephric renal vesicle morphogenesis(GO:0072283)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.2 GO:0032770 positive regulation of monooxygenase activity(GO:0032770)
0.0 0.0 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.0 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:0035930 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.0 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.0 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0099518 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.1 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.0 GO:0043259 laminin-10 complex(GO:0043259)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins