Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NFAT5

Z-value: 1.57

Motif logo

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Transcription factors associated with NFAT5

Gene Symbol Gene ID Gene Info
ENSG00000102908.16 NFAT5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NFAT5chr16_69564743_69565075340880.1381920.703.6e-02Click!
NFAT5chr16_69602369_6960284423520.2619990.655.9e-02Click!
NFAT5chr16_69598102_695982778080.5479230.599.7e-02Click!
NFAT5chr16_69602932_6960308327530.2425760.599.7e-02Click!
NFAT5chr16_69598329_695984805930.6530260.561.1e-01Click!

Activity of the NFAT5 motif across conditions

Conditions sorted by the z-value of the NFAT5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_76211856_76212147 0.49 LMO7
LIM domain 7
1542
0.32
chr22_40672790_40673085 0.47 TNRC6B
trinucleotide repeat containing 6B
11930
0.23
chr10_5490099_5490572 0.42 NET1
neuroepithelial cell transforming 1
1761
0.33
chr10_13748985_13749251 0.40 ENSG00000222235
.
2140
0.21
chr14_61203018_61203182 0.40 MNAT1
MNAT CDK-activating kinase assembly factor 1
1606
0.42
chr1_20811158_20811808 0.40 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
1230
0.48
chr9_131999660_131999903 0.39 ENSG00000220992
.
6785
0.18
chr12_68044407_68044686 0.37 DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
703
0.77
chr8_79716569_79716762 0.37 IL7
interleukin 7
498
0.88
chr12_93966268_93967071 0.36 SOCS2
suppressor of cytokine signaling 2
758
0.51
chr7_78158570_78158721 0.36 MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
241751
0.02
chr21_33982977_33983128 0.36 AP000275.65
Uncharacterized protein
1404
0.29
chr8_61048624_61048775 0.35 CA8
carbonic anhydrase VIII
145272
0.05
chr1_116918127_116918427 0.35 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
1788
0.31
chr11_12696722_12697409 0.35 TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
15
0.99
chr11_120208214_120208431 0.34 ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
376
0.86
chr6_28952769_28953226 0.34 HCG15
HLA complex group 15 (non-protein coding)
983
0.36
chr8_17554662_17554991 0.34 MTUS1
microtubule associated tumor suppressor 1
353
0.86
chrX_16856707_16856878 0.34 RBBP7
retinoblastoma binding protein 7
13396
0.17
chr10_64144878_64145029 0.34 ZNF365
zinc finger protein 365
9650
0.25
chr14_98443744_98443895 0.34 C14orf64
chromosome 14 open reading frame 64
564
0.87
chr2_238136824_238136987 0.34 AC112715.2
Uncharacterized protein
28829
0.22
chr1_108190559_108190746 0.34 VAV3
vav 3 guanine nucleotide exchange factor
40474
0.21
chr4_54407445_54407630 0.34 LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
16847
0.2
chr13_75793783_75793953 0.33 ENSG00000266534
.
10695
0.28
chr17_40933836_40933987 0.33 WNK4
WNK lysine deficient protein kinase 4
1215
0.25
chrX_39186546_39186697 0.32 ENSG00000207122
.
246083
0.02
chr22_37545005_37545248 0.32 IL2RB
interleukin 2 receptor, beta
904
0.44
chr14_61794973_61795256 0.32 PRKCH
protein kinase C, eta
1483
0.41
chr2_202900721_202900872 0.32 FZD7
frizzled family receptor 7
1486
0.39
chr10_13143763_13143957 0.31 OPTN
optineurin
1635
0.34
chr4_149364442_149364596 0.30 NR3C2
nuclear receptor subfamily 3, group C, member 2
847
0.76
chr9_98335232_98335383 0.30 PTCH1
patched 1
55968
0.12
chr2_39964531_39964918 0.30 THUMPD2
THUMP domain containing 2
41565
0.16
chrX_103172868_103173181 0.30 TMSB15B
thymosin beta 15B
455
0.68
chr12_93561615_93562183 0.30 RP11-511B23.2

28991
0.18
chr11_33398594_33398861 0.29 ENSG00000223134
.
22716
0.24
chr6_28921272_28921906 0.29 C6orf100
chromosome 6 open reading frame 100
9935
0.12
chr14_64192784_64192935 0.28 SGPP1
sphingosine-1-phosphate phosphatase 1
1898
0.32
chr3_99593193_99593490 0.28 FILIP1L
filamin A interacting protein 1-like
1607
0.48
chr11_12398813_12399038 0.28 PARVA
parvin, alpha
185
0.96
chr2_233499497_233499648 0.28 EFHD1
EF-hand domain family, member D1
1634
0.27
chr16_68299633_68299784 0.28 SLC7A6
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
289
0.77
chr2_54747561_54747712 0.28 AC092839.3

20198
0.18
chr11_44009399_44009698 0.28 C11orf96
chromosome 11 open reading frame 96
45493
0.11
chr2_216299709_216300678 0.28 FN1
fibronectin 1
597
0.55
chr7_41147488_41147710 0.28 AC005160.3

332442
0.01
chr10_369743_369908 0.27 DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
5641
0.22
chr20_57425359_57425924 0.27 GNAS-AS1
GNAS antisense RNA 1
292
0.85
chr11_102146918_102147069 0.27 ENSG00000212466
.
37460
0.13
chr12_64216100_64216557 0.27 TMEM5-AS1
TMEM5 antisense RNA 1
392
0.81
chr1_201436884_201437966 0.27 PHLDA3
pleckstrin homology-like domain, family A, member 3
887
0.55
chr10_124638343_124639057 0.27 FAM24B
family with sequence similarity 24, member B
414
0.49
chr6_106549542_106549744 0.27 RP1-134E15.3

1628
0.4
chr8_79428640_79429327 0.27 PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
393
0.91
chr4_10734070_10734358 0.27 CLNK
cytokine-dependent hematopoietic cell linker
47725
0.2
chr17_4146121_4146272 0.27 ANKFY1
ankyrin repeat and FYVE domain containing 1
20946
0.15
chr22_39095661_39095849 0.26 JOSD1
Josephin domain containing 1
220
0.84
chr3_121196713_121196995 0.26 POLQ
polymerase (DNA directed), theta
67999
0.11
chr17_38599985_38600404 0.26 IGFBP4
insulin-like growth factor binding protein 4
481
0.74
chr13_100308254_100308545 0.26 ENSG00000263615
.
13086
0.18
chr11_49427773_49427924 0.26 CTD-2026G22.1

100582
0.08
chr2_191224464_191225199 0.26 INPP1
inositol polyphosphate-1-phosphatase
3569
0.24
chr1_113248598_113248962 0.26 RHOC
ras homolog family member C
898
0.4
chr5_50040977_50041222 0.25 PARP8
poly (ADP-ribose) polymerase family, member 8
77708
0.12
chr5_52489701_52489852 0.25 MOCS2
molybdenum cofactor synthesis 2
83883
0.09
chr22_43186898_43187049 0.25 ENSG00000200448
.
28008
0.16
chr12_47611625_47611801 0.25 PCED1B
PC-esterase domain containing 1B
1332
0.49
chr3_145877802_145878044 0.25 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
856
0.67
chr21_44465720_44465948 0.25 CBS
cystathionine-beta-synthase
13217
0.18
chr6_136360177_136360429 0.25 RP13-143G15.3

25473
0.21
chr7_47835377_47835528 0.25 C7orf69
chromosome 7 open reading frame 69
430
0.85
chr10_91179525_91179676 0.25 IFIT5
interferon-induced protein with tetratricopeptide repeats 5
5081
0.15
chr15_37389081_37389380 0.25 MEIS2
Meis homeobox 2
338
0.88
chr2_220554088_220554302 0.25 SLC4A3
solute carrier family 4 (anion exchanger), member 3
58343
0.08
chr16_58161346_58161534 0.25 C16orf80
chromosome 16 open reading frame 80
1825
0.22
chr6_136201278_136201627 0.25 PDE7B
phosphodiesterase 7B
28618
0.19
chr19_37407798_37408074 0.25 ZNF568
zinc finger protein 568
579
0.5
chr10_17708003_17708331 0.24 ENSG00000251959
.
13020
0.15
chr10_6625397_6625548 0.24 PRKCQ
protein kinase C, theta
3209
0.39
chr5_150004973_150005202 0.24 SYNPO
synaptopodin
7881
0.15
chr8_18870145_18870375 0.24 PSD3
pleckstrin and Sec7 domain containing 3
936
0.62
chr1_109740352_109740715 0.24 ENSG00000238310
.
9937
0.15
chr10_13142514_13143212 0.24 OPTN
optineurin
638
0.62
chr2_101435204_101435829 0.24 NPAS2
neuronal PAS domain protein 2
1098
0.54
chr20_43211779_43211930 0.24 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
664
0.66
chr18_42369803_42369954 0.24 SETBP1
SET binding protein 1
92749
0.1
chr4_138452558_138452766 0.24 PCDH18
protocadherin 18
903
0.76
chr6_148593838_148594147 0.24 SASH1
SAM and SH3 domain containing 1
552
0.78
chr13_110999770_111000142 0.24 COL4A2
collagen, type IV, alpha 2
40342
0.15
chr5_156617150_156617301 0.23 ITK
IL2-inducible T-cell kinase
9388
0.13
chr1_109373474_109373674 0.23 AKNAD1
AKNA domain containing 1
21765
0.15
chr17_59475345_59475496 0.23 RP11-332H18.4

1311
0.28
chr2_157749235_157750071 0.23 ENSG00000263848
.
122116
0.06
chr15_86402023_86402174 0.23 ENSG00000264406
.
33232
0.14
chr3_181433400_181433551 0.23 SOX2
SRY (sex determining region Y)-box 2
3753
0.28
chr6_131384985_131385136 0.23 EPB41L2
erythrocyte membrane protein band 4.1-like 2
598
0.84
chr20_25581543_25581694 0.23 ENSG00000251883
.
10171
0.15
chr10_95239483_95239707 0.23 MYOF
myoferlin
2356
0.29
chr18_41427432_41427597 0.23 ENSG00000202250
.
15284
0.31
chr3_152018701_152018852 0.23 MBNL1
muscleblind-like splicing regulator 1
789
0.69
chr16_89380681_89380904 0.23 AC137932.6

6749
0.14
chr11_84148388_84148632 0.23 DLG2
discs, large homolog 2 (Drosophila)
120128
0.07
chr20_52380389_52380540 0.23 ENSG00000238468
.
95167
0.08
chr10_26846763_26846969 0.23 ENSG00000199733
.
48348
0.17
chr10_33242762_33242913 0.23 ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
1754
0.49
chr8_23827287_23827438 0.23 ENSG00000207201
.
107309
0.06
chr13_49391513_49391676 0.23 ENSG00000222391
.
65302
0.12
chr8_11057517_11057710 0.23 XKR6
XK, Kell blood group complex subunit-related family, member 6
1235
0.45
chr4_154178583_154178757 0.22 TRIM2
tripartite motif containing 2
108
0.96
chr10_3821655_3821946 0.22 KLF6
Kruppel-like factor 6
5585
0.23
chr8_77316490_77316641 0.22 ENSG00000222231
.
138598
0.05
chr7_72680557_72680730 0.22 GTF2IRD2P1
GTF2I repeat domain containing 2 pseudogene 1
13500
0.15
chr2_113915683_113915966 0.22 PSD4
pleckstrin and Sec7 domain containing 4
15724
0.13
chr2_111229826_111230082 0.22 LIMS3
LIM and senescent cell antigen-like-containing domain protein 3; Uncharacterized protein; cDNA FLJ59124, highly similar to Particularly interesting newCys-His protein; cDNA, FLJ79109, highly similar to Particularly interesting newCys-His protein
439
0.46
chr2_121673049_121673299 0.22 GLI2
GLI family zinc finger 2
118253
0.06
chr10_91462306_91462457 0.22 KIF20B
kinesin family member 20B
945
0.63
chr12_49487769_49488001 0.22 DHH
desert hedgehog
717
0.43
chr4_154851186_154851337 0.22 ENSG00000252181
.
56658
0.15
chr4_81192022_81192173 0.22 FGF5
fibroblast growth factor 5
4304
0.29
chr3_160120309_160120698 0.22 ENSG00000207779
.
1873
0.2
chr1_95394705_95395023 0.22 RP4-639F20.1

1280
0.4
chr2_181971569_181971726 0.22 UBE2E3
ubiquitin-conjugating enzyme E2E 3
124897
0.06
chr18_9787496_9787647 0.22 ENSG00000242651
.
43053
0.14
chr14_105434639_105435137 0.22 AHNAK2
AHNAK nucleoprotein 2
9806
0.16
chr8_79428088_79428454 0.22 PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
103
0.98
chr17_49244555_49245055 0.22 NME1-NME2
NME1-NME2 readthrough
880
0.52
chr1_54232914_54233120 0.21 ENSG00000201003
.
3809
0.22
chr10_26775632_26775856 0.21 ENSG00000199733
.
22774
0.23
chr2_202766440_202766591 0.21 ENSG00000212184
.
25647
0.16
chr11_12029832_12030027 0.21 DKK3
dickkopf WNT signaling pathway inhibitor 3
201
0.97
chr11_35061934_35062494 0.21 PDHX
pyruvate dehydrogenase complex, component X
62883
0.1
chr7_101397584_101398512 0.21 CUX1
cut-like homeobox 1
60911
0.12
chr20_4668017_4668400 0.21 PRNP
prion protein
1019
0.59
chr20_25603637_25603832 0.21 ZNF337-AS1
ZNF337 antisense RNA 1
947
0.37
chr2_30456555_30456706 0.21 LBH
limb bud and heart development
1584
0.45
chr5_172752767_172752937 0.21 STC2
stanniocalcin 2
948
0.57
chrY_16636680_16636898 0.21 NLGN4Y
neuroligin 4, Y-linked
335
0.94
chr2_216296824_216297216 0.21 FN1
fibronectin 1
3770
0.26
chr3_27763469_27763904 0.21 EOMES
eomesodermin
117
0.98
chr1_172110530_172111247 0.21 ENSG00000207949
.
2841
0.22
chr14_56047603_56047881 0.21 KTN1
kinectin 1 (kinesin receptor)
700
0.52
chr1_222638968_222639286 0.21 ENSG00000222399
.
37950
0.18
chr20_19476927_19477078 0.21 ENSG00000216017
.
93829
0.08
chr19_18386391_18386725 0.21 KIAA1683
KIAA1683
1239
0.28
chr14_22615939_22616090 0.21 ENSG00000238634
.
5127
0.32
chr7_373305_373494 0.21 AC187652.1
Protein LOC100996433
70481
0.11
chr19_49315745_49315992 0.21 BCAT2
branched chain amino-acid transaminase 2, mitochondrial
1582
0.2
chr22_46489955_46490106 0.21 ENSG00000266533
.
3106
0.13
chr7_856966_857451 0.21 SUN1
Sad1 and UNC84 domain containing 1
705
0.68
chr4_48114354_48114527 0.21 TXK
TXK tyrosine kinase
2122
0.24
chr20_57092292_57092443 0.21 APCDD1L
adenomatosis polyposis coli down-regulated 1-like
2180
0.38
chr14_97604017_97604168 0.21 VRK1
vaccinia related kinase 1
261726
0.02
chr21_32666145_32666463 0.20 TIAM1
T-cell lymphoma invasion and metastasis 1
17221
0.28
chr5_57753332_57753483 0.20 PLK2
polo-like kinase 2
2680
0.32
chr5_77189257_77189408 0.20 TBCA
tubulin folding cofactor A
24728
0.26
chr3_23245219_23245473 0.20 UBE2E2
ubiquitin-conjugating enzyme E2E 2
562
0.7
chr12_80794918_80795130 0.20 PTPRQ
protein tyrosine phosphatase, receptor type, Q
4750
0.27
chr14_51229593_51229744 0.20 NIN
ninein (GSK3B interacting protein)
3845
0.21
chr7_19145822_19145973 0.20 AC003986.6

6200
0.17
chr12_29696081_29696326 0.20 RP11-310I24.1

23539
0.2
chr15_38854880_38855238 0.20 RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
1777
0.36
chr12_64239539_64239880 0.20 SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
1168
0.42
chr1_90097966_90098438 0.20 RP5-1007M22.2

104
0.83
chr11_128027774_128027972 0.20 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
347416
0.01
chr8_124070190_124070341 0.20 ENSG00000199678
.
13308
0.15
chr10_63730091_63730242 0.20 ENSG00000221272
.
43389
0.18
chr1_166874743_166874894 0.20 TADA1
transcriptional adaptor 1
29254
0.17
chr10_88718408_88718568 0.20 SNCG
synuclein, gamma (breast cancer-specific protein 1)
75
0.91
chr2_202929173_202929352 0.20 AC079354.1
uncharacterized protein KIAA2012
8716
0.16
chrX_153627641_153627899 0.20 RPL10
ribosomal protein L10
63
0.9
chr7_130594661_130594812 0.20 ENSG00000226380
.
32438
0.2
chr14_21081978_21082639 0.20 RNASE11
ribonuclease, RNase A family, 11 (non-active)
4265
0.13
chr12_86228304_86228474 0.20 RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
1959
0.44
chr7_100775090_100775413 0.20 SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
4872
0.12
chr1_204548801_204548952 0.20 ENSG00000200408
.
17227
0.14
chr20_6556799_6556950 0.20 BMP2
bone morphogenetic protein 2
191437
0.03
chr17_1690666_1690823 0.20 SMYD4
SET and MYND domain containing 4
13355
0.11
chr18_21573835_21574026 0.20 TTC39C
tetratricopeptide repeat domain 39C
1193
0.47
chr1_32718292_32718517 0.20 LCK
lymphocyte-specific protein tyrosine kinase
1529
0.2
chr20_53092813_53093232 0.20 DOK5
docking protein 5
765
0.8
chr8_95274728_95274984 0.20 GEM
GTP binding protein overexpressed in skeletal muscle
278
0.94
chr3_124554463_124554736 0.20 ITGB5
integrin, beta 5
5799
0.23
chr7_22757656_22757807 0.20 IL6
interleukin 6 (interferon, beta 2)
7772
0.19
chr8_122273630_122273781 0.20 ENSG00000221644
.
74573
0.13
chr16_86254541_86254692 0.20 ENSG00000199949
.
54513
0.17
chr8_49293521_49293747 0.20 ENSG00000252710
.
73044
0.13
chr10_6771504_6771655 0.20 PRKCQ
protein kinase C, theta
149316
0.05
chr1_119531356_119531507 0.20 TBX15
T-box 15
748
0.76
chr17_38776366_38776617 0.20 SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
12051
0.14
chr22_30639387_30639538 0.20 RP1-102K2.8

2522
0.15
chr8_103540415_103540568 0.20 KB-1980E6.3
Uncharacterized protein
492
0.78
chr16_11876754_11877323 0.20 ZC3H7A
zinc finger CCCH-type containing 7A
148
0.95
chr4_6783352_6783503 0.20 KIAA0232
KIAA0232
942
0.6
chr10_27917420_27917571 0.20 MKX
mohawk homeobox
114979
0.06
chr10_45374254_45374405 0.20 TMEM72
transmembrane protein 72
32319
0.15
chr11_133825183_133825417 0.19 ENSG00000264674
.
1464
0.34
chr14_55178946_55179143 0.19 SAMD4A
sterile alpha motif domain containing 4A
42507
0.18
chr1_42383823_42384248 0.19 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
134
0.98
chr14_99713029_99713259 0.19 AL109767.1

16141
0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NFAT5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008049 male courtship behavior(GO:0008049)
0.1 0.3 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.3 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 0.3 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.1 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.1 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.1 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 0.1 GO:0072162 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 0.3 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.1 GO:0071071 regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.2 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1 0.2 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0072071 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0 0.3 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.2 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0032819 positive regulation of natural killer cell proliferation(GO:0032819)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.3 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.3 GO:0021591 ventricular system development(GO:0021591)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.3 GO:0031579 membrane raft organization(GO:0031579)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.5 GO:1902749 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.3 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.0 GO:0048368 regulation of mesodermal cell fate specification(GO:0042661) lateral mesoderm development(GO:0048368) regulation of mesoderm development(GO:2000380)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0061437 renal system vasculature development(GO:0061437) kidney vasculature development(GO:0061440) glomerulus vasculature development(GO:0072012) glomerular mesangium development(GO:0072109) glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.4 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.0 GO:0003207 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.1 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.6 GO:0060603 mammary gland duct morphogenesis(GO:0060603)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.2 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.0 GO:0035385 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827) Roundabout signaling pathway(GO:0035385)
0.0 0.2 GO:0015840 urea transport(GO:0015840)
0.0 0.2 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.1 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0060413 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.0 GO:0060087 relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.0 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.3 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.1 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 0.0 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.0 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:1905209 positive regulation of cardioblast differentiation(GO:0051891) positive regulation of cardiocyte differentiation(GO:1905209)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.1 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.0 GO:0031223 response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.1 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.0 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.2 GO:0010171 body morphogenesis(GO:0010171)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0030825 positive regulation of cGMP metabolic process(GO:0030825)
0.0 0.0 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.0 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.0 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.0 0.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0060008 Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0 0.0 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.0 GO:0031063 regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0000462 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0071675 positive regulation of macrophage chemotaxis(GO:0010759) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.0 GO:0035269 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.2 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.0 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0035121 obsolete tail morphogenesis(GO:0035121)
0.0 0.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0043631 RNA polyadenylation(GO:0043631)
0.0 0.0 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.2 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.1 GO:0031529 ruffle organization(GO:0031529)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.0 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0035587 purinergic receptor signaling pathway(GO:0035587)
0.0 0.0 GO:0070875 positive regulation of glycogen metabolic process(GO:0070875)
0.0 0.0 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.0 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.0 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.1 GO:0044550 secondary metabolite biosynthetic process(GO:0044550)
0.0 0.0 GO:0033084 immature T cell proliferation in thymus(GO:0033080) regulation of immature T cell proliferation in thymus(GO:0033084)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.0 GO:2000189 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.0 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.2 GO:0031670 cellular response to nutrient(GO:0031670)
0.0 0.0 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.0 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.0 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.0 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.1 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.0 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.0 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.1 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.0 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.0 GO:0008218 bioluminescence(GO:0008218)
0.0 0.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.0 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.1 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.0 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.0 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.0 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.0 GO:1901890 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.1 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.0 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.4 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.1 GO:0002090 regulation of receptor internalization(GO:0002090)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.2 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.0 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 1.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.0 GO:0018995 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.0 GO:0016600 flotillin complex(GO:0016600)
0.0 0.0 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.9 GO:0019717 obsolete synaptosome(GO:0019717)
0.0 0.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.3 GO:0005113 patched binding(GO:0005113)
0.1 0.3 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0044620 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.0 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.0 GO:0046980 tapasin binding(GO:0046980)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0045296 cadherin binding(GO:0045296)
0.0 1.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.0 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.0 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.0 GO:0034452 dynactin binding(GO:0034452)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.0 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.0 PID INSULIN PATHWAY Insulin Pathway
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.4 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.2 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters