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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NFATC1

Z-value: 1.75

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Transcription factors associated with NFATC1

Gene Symbol	Gene ID	Gene Info
NFATC1 Ensembl NCBI GeneCards UniProt	ENSG00000131196.13	NFATC1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
NFATC1	chr18_77159557_77160137	475	0.855604	-0.83	5.5e-03	Click!
NFATC1	chr18_77159340_77159496	904	0.662874	-0.77	1.4e-02	Click!
NFATC1	chr18_77165970_77166171	5678	0.264296	-0.71	3.1e-02	Click!
NFATC1	chr18_77160344_77160704	132	0.972457	-0.71	3.1e-02	Click!
NFATC1	chr18_77165463_77165878	5278	0.268046	-0.67	4.8e-02	Click!

Activity of the NFATC1 motif across conditions

Conditions sorted by the z-value of the NFATC1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr21_17960305_17960805	0.80	ENSG00000207863	.	2002	0.4
chr6_23004070_23004285	0.74	ENSG00000207394	.	121138	0.07
chr19_34359259_34359976	0.73	ENSG00000240626	.	58913	0.13
chr17_79317268_79317735	0.70	TMEM105	transmembrane protein 105	13027	0.13
chr12_116872831_116873001	0.70	ENSG00000264037	.	6793	0.3
chr4_55096373_55096991	0.70	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	193	0.97
chr3_25469138_25469713	0.68	RARB	retinoic acid receptor, beta	329	0.93
chr3_98618999_98619299	0.64	DCBLD2	discoidin, CUB and LCCL domain containing 2	866	0.54
chr6_97545575_97545734	0.62	KLHL32	kelch-like family member 32	33150	0.23
chr4_81189966_81190509	0.61	FGF5	fibroblast growth factor 5	2444	0.36
chr7_70201396_70202343	0.59	AUTS2	autism susceptibility candidate 2	7744	0.34
chr5_38846105_38846894	0.59	OSMR	oncostatin M receptor	398	0.91
chr4_114680063_114680214	0.57	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	2086	0.48
chr13_40174017_40174396	0.57	LHFP	lipoma HMGIC fusion partner	3102	0.29
chr11_8831505_8831934	0.54	ST5	suppression of tumorigenicity 5	477	0.76
chr20_19956550_19956867	0.54	NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit	41052	0.15
chr2_227049788_227050011	0.53	ENSG00000263363	.	473610	0.01
chr22_45865037_45865472	0.52	RP1-102D24.5		20630	0.17
chrX_8836868_8837019	0.52	FAM9A	family with sequence similarity 9, member A	67519	0.13
chr5_142777353_142777556	0.51	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	2963	0.39
chr8_72776934_72777085	0.51	MSC	musculin	20306	0.17
chr3_114404388_114404544	0.51	ENSG00000264623	.	57906	0.14
chr13_76212170_76212445	0.51	LMO7	LIM domain 7	1848	0.28
chr2_218843405_218844030	0.51	TNS1	tensin 1	60	0.79
chr14_50987831_50988146	0.51	MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	11202	0.18
chr5_95768411_95768678	0.51	PCSK1	proprotein convertase subtilisin/kexin type 1	440	0.89
chr4_81192022_81192173	0.51	FGF5	fibroblast growth factor 5	4304	0.29
chr8_89311514_89311910	0.50	RP11-586K2.1		27353	0.2
chr1_95388573_95389173	0.50	CNN3	calponin 3, acidic	2464	0.27
chr12_59311038_59311457	0.49	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	2080	0.36
chr20_30084575_30084759	0.49	HM13	histocompatibility (minor) 13	17564	0.11
chr1_98514742_98514981	0.49	ENSG00000225206	.	3134	0.4
chr9_22446798_22447485	0.48	DMRTA1	DMRT-like family A1	301	0.95
chr6_35182117_35182910	0.48	SCUBE3	signal peptide, CUB domain, EGF-like 3	317	0.9
chr4_181748689_181748884	0.48	NA	NA	> 10⁶	NA
chr4_123719295_123719464	0.48	FGF2	fibroblast growth factor 2 (basic)	28484	0.16
chr8_92612283_92612746	0.47	ENSG00000200151	.	5321	0.33
chr9_117879769_117880175	0.47	TNC	tenascin C	506	0.85
chr12_109226312_109226796	0.47	ENSG00000207622	.	4228	0.18
chr8_24366846_24366997	0.47	RP11-561E1.1		5180	0.24
chr4_176922498_176923243	0.46	GPM6A	glycoprotein M6A	613	0.78
chr5_54128157_54128308	0.46	ENSG00000221073	.	20544	0.24
chr12_88812633_88812784	0.46	ENSG00000199245	.	11511	0.3
chr16_62068318_62068835	0.46	CDH8	cadherin 8, type 2	462	0.9
chr9_79520622_79521003	0.45	PRUNE2	prune homolog 2 (Drosophila)	189	0.97
chr10_128593931_128594173	0.45	DOCK1	dedicator of cytokinesis 1	74	0.98
chr20_39944817_39945241	0.45	ZHX3	zinc fingers and homeoboxes 3	797	0.64
chr10_116444886_116445037	0.45	ABLIM1	actin binding LIM protein 1	547	0.83
chr6_72075753_72076050	0.44	ENSG00000199094	.	10833	0.2
chr6_150176715_150177267	0.44	RP11-350J20.12		3393	0.15
chr2_151340168_151340387	0.44	RND3	Rho family GTPase 3	1619	0.57
chr2_210288891_210289443	0.44	MAP2	microtubule-associated protein 2	385	0.93
chr2_176996093_176996244	0.44	HOXD8	homeobox D8	1083	0.26
chr8_13369656_13370025	0.43	DLC1	deleted in liver cancer 1	2434	0.32
chr4_157889287_157889693	0.43	PDGFC	platelet derived growth factor C	2565	0.32
chr9_129916828_129917272	0.43	ANGPTL2	angiopoietin-like 2	31888	0.16
chr19_56166514_56167932	0.43	U2AF2	U2 small nuclear RNA auxiliary factor 2	792	0.34
chr1_147717990_147718807	0.42	ENSG00000199879	.	17353	0.18
chr16_64245174_64245639	0.42	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	848175	0.0
chr12_79257392_79257783	0.42	SYT1	synaptotagmin I	186	0.97
chr8_17611273_17611424	0.42	MTUS1	microtubule associated tumor suppressor 1	2142	0.28
chr13_22053308_22053484	0.42	ZDHHC20	zinc finger, DHHC-type containing 20	19887	0.19
chr13_76211856_76212147	0.42	LMO7	LIM domain 7	1542	0.32
chr10_30471562_30471725	0.42	ENSG00000200887	.	116959	0.06
chr11_97853691_97853842	0.42	ENSG00000216073	.	69877	0.14
chr7_100771614_100771864	0.42	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	1360	0.28
chr18_46848436_46848639	0.42	DYM	dymeclin	46530	0.14
chr2_239696091_239696242	0.41	TWIST2	twist family bHLH transcription factor 2	60507	0.14
chr12_116819288_116819767	0.41	ENSG00000264037	.	46596	0.17
chr14_56711281_56711464	0.41	PELI2	pellino E3 ubiquitin protein ligase family member 2	125545	0.06
chr10_77156249_77156959	0.41	ENSG00000237149	.	4673	0.21
chr8_86350363_86351282	0.41	CA3	carbonic anhydrase III, muscle specific	234	0.93
chr1_162602307_162602458	0.41	DDR2	discoidin domain receptor tyrosine kinase 2	122	0.97
chr5_146887879_146888030	0.41	DPYSL3	dihydropyrimidinase-like 3	1665	0.51
chr8_93074610_93074813	0.41	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	480	0.89
chr5_81701799_81702115	0.41	ATP6AP1L	ATPase, H+ transporting, lysosomal accessory protein 1-like	100791	0.08
chr18_54070935_54071139	0.41	TXNL1	thioredoxin-like 1	210685	0.02
chr1_174389053_174389221	0.40	GPR52	G protein-coupled receptor 52	28075	0.23
chr14_79745937_79746359	0.40	NRXN3	neurexin 3	101	0.98
chr4_186577993_186578477	0.40	SORBS2	sorbin and SH3 domain containing 2	112	0.97
chr10_17274225_17274484	0.40	VIM	vimentin	1746	0.26
chr5_39421239_39421390	0.40	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	3656	0.34
chr2_17721828_17722425	0.40	VSNL1	visinin-like 1	163	0.97
chr5_16916952_16917142	0.40	MYO10	myosin X	411	0.87
chr14_89973651_89973935	0.40	FOXN3	forkhead box N3	13264	0.2
chr1_90321564_90321715	0.40	LRRC8D	leucine rich repeat containing 8 family, member D	9500	0.25
chr5_13986133_13986412	0.40	DNAH5	dynein, axonemal, heavy chain 5	41620	0.21
chr4_88939495_88939878	0.40	PKD2	polycystic kidney disease 2 (autosomal dominant)	10866	0.19
chr9_112555819_112555970	0.39	AKAP2	A kinase (PRKA) anchor protein 2	13125	0.16
chr9_111861305_111861456	0.39	TMEM245	transmembrane protein 245	11807	0.18
chr22_46453843_46454104	0.39	RP6-109B7.3		3178	0.13
chr10_124254663_124255115	0.39	HTRA1	HtrA serine peptidase 1	11318	0.2
chr9_75771174_75771814	0.39	ANXA1	annexin A1	1076	0.66
chr11_88242003_88242805	0.39	GRM5-AS1	GRM5 antisense RNA 1	2512	0.42
chr1_242310080_242310365	0.39	RP11-561I11.4		594	0.75
chr13_24807615_24808021	0.39	SPATA13	spermatogenesis associated 13	18014	0.17
chr5_169406944_169407149	0.39	FAM196B	family with sequence similarity 196, member B	698	0.77
chr6_131291045_131291463	0.38	EPB41L2	erythrocyte membrane protein band 4.1-like 2	369	0.93
chr12_13326265_13326502	0.38	EMP1	epithelial membrane protein 1	23267	0.21
chr17_15686261_15686502	0.38	ENSG00000251829	.	726	0.64
chr2_50876595_50876746	0.38	ENSG00000216191	.	46730	0.19
chr15_95847511_95847662	0.38	ENSG00000222076	.	441447	0.01
chr9_686616_686767	0.38	RP11-130C19.3		1136	0.55
chr10_35098017_35098428	0.38	PARD3	par-3 family cell polarity regulator	6027	0.24
chr6_3825964_3826270	0.38	RP11-420L9.4		6050	0.22
chr2_221969079_221969387	0.38	EPHA4	EPH receptor A4	398047	0.01
chrX_25022630_25023098	0.38	ARX	aristaless related homeobox	11201	0.27
chr7_105705584_105705867	0.38	SYPL1	synaptophysin-like 1	32583	0.2
chr6_28641788_28642196	0.37	ENSG00000272278	.	25950	0.18
chr8_77594044_77594273	0.37	ZFHX4	zinc finger homeobox 4	604	0.67
chr12_88973184_88973445	0.37	KITLG	KIT ligand	924	0.59
chr14_91585821_91585989	0.37	C14orf159	chromosome 14 open reading frame 159	4861	0.17
chr12_88969721_88970003	0.37	KITLG	KIT ligand	4376	0.27
chr12_66222342_66222753	0.37	HMGA2	high mobility group AT-hook 2	3644	0.26
chr8_125212210_125212404	0.36	FER1L6-AS2	FER1L6 antisense RNA 2	28544	0.2
chr12_65997737_65997888	0.36	HMGA2	high mobility group AT-hook 2	220099	0.02
chr18_66465448_66465631	0.36	CCDC102B	coiled-coil domain containing 102B	113	0.97
chr3_157335850_157336001	0.36	C3orf55	chromosome 3 open reading frame 55	74692	0.11
chr1_185688405_185688780	0.36	HMCN1	hemicentin 1	15091	0.26
chr13_29132587_29132851	0.36	FLT1	fms-related tyrosine kinase 1	63454	0.13
chr19_47735595_47736220	0.36	BBC3	BCL2 binding component 3	116	0.95
chr7_116168289_116168733	0.36	CAV1	caveolin 1, caveolae protein, 22kDa	2164	0.26
chr2_28183635_28183870	0.36	ENSG00000265321	.	35482	0.16
chr10_15721874_15722025	0.36	ITGA8	integrin, alpha 8	40175	0.21
chr1_65005729_65006114	0.36	ENSG00000264470	.	39609	0.19
chrX_78003533_78003765	0.36	LPAR4	lysophosphatidic acid receptor 4	421	0.91
chr6_27512445_27512692	0.36	ENSG00000206671	.	51623	0.12
chr10_95802546_95802812	0.35	ENSG00000252895	.	4203	0.22
chr13_39343461_39343612	0.35	ENSG00000252795	.	10025	0.21
chr4_54948203_54948354	0.35	CHIC2	cysteine-rich hydrophobic domain 2	17421	0.14
chr17_43047514_43047990	0.35	C1QL1	complement component 1, q subcomponent-like 1	2313	0.2
chr2_169675855_169676058	0.35	NOSTRIN	nitric oxide synthase trafficking	8112	0.22
chr10_70752333_70752623	0.35	KIAA1279	KIAA1279	3991	0.2
chr3_156570645_156570796	0.35	LEKR1	leucine, glutamate and lysine rich 1	26572	0.24
chr12_18536570_18536736	0.35	PIK3C2G	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma	101675	0.08
chr5_111084206_111084519	0.35	NREP	neuronal regeneration related protein	7586	0.21
chr8_69672880_69673031	0.35	ENSG00000239184	.	65077	0.15
chr16_11444934_11445085	0.35	RP11-485G7.6		1831	0.18
chr2_63276750_63277690	0.35	OTX1	orthodenticle homeobox 1	28	0.97
chr6_158182224_158182417	0.35	SNX9	sorting nexin 9	61976	0.12
chrX_71905796_71905947	0.34	PHKA1-AS1	PHKA1 antisense RNA 1	2929	0.24
chr7_27218725_27218915	0.34	RP1-170O19.20	Uncharacterized protein	812	0.27
chr10_74562802_74562983	0.34	RP11-354E23.5		36574	0.15
chr5_138206284_138206563	0.34	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	3304	0.25
chr13_76259054_76259476	0.34	LMO7	LIM domain 7	48806	0.13
chr5_121412020_121412268	0.34	LOX	lysyl oxidase	1836	0.4
chr5_141980216_141980760	0.34	AC005592.2		19075	0.18
chr18_10058041_10058330	0.34	ENSG00000263630	.	52991	0.15
chr2_19557319_19557513	0.34	OSR1	odd-skipped related transciption factor 1	739	0.74
chr3_100515408_100515559	0.34	ABI3BP	ABI family, member 3 (NESH) binding protein	8205	0.28
chr2_38265076_38265999	0.34	RMDN2-AS1	RMDN2 antisense RNA 1	2053	0.33
chr1_178207524_178207696	0.34	RASAL2	RAS protein activator like 2	102996	0.08
chr4_14864468_14865022	0.34	CPEB2	cytoplasmic polyadenylation element binding protein 2	139553	0.05
chr14_90280432_90280702	0.34	ENSG00000200312	.	101712	0.07
chr7_121513797_121514084	0.34	PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	525	0.87
chr10_44788968_44789259	0.34	RP11-20J15.3		44	0.99
chr5_39102785_39103048	0.34	AC008964.1		2442	0.36
chr1_218672222_218672541	0.34	C1orf143	chromosome 1 open reading frame 143	11057	0.26
chr10_104536223_104536534	0.34	WBP1L	WW domain binding protein 1-like	372	0.83
chr6_25312716_25313084	0.34	ENSG00000207286	.	25139	0.15
chr4_95466530_95466732	0.34	PDLIM5	PDZ and LIM domain 5	21755	0.28
chr5_77189257_77189408	0.33	TBCA	tubulin folding cofactor A	24728	0.26
chr11_78021681_78021861	0.33	RP11-452H21.1		14033	0.18
chr1_234669487_234669677	0.33	TARBP1	TAR (HIV-1) RNA binding protein 1	54733	0.11
chr15_36623727_36623943	0.33	C15orf41	chromosome 15 open reading frame 41	247977	0.02
chr12_53443889_53444561	0.33	TENC1	tensin like C1 domain containing phosphatase (tensin 2)	255	0.86
chr1_185687957_185688174	0.33	HMCN1	hemicentin 1	15618	0.26
chr7_15724696_15724847	0.33	MEOX2	mesenchyme homeobox 2	1666	0.46
chr1_107684993_107685186	0.33	NTNG1	netrin G1	1428	0.58
chr7_104621470_104621621	0.33	ENSG00000251911	.	9811	0.17
chr19_52452059_52452669	0.33	HCCAT3	hepatocellular carcinoma associated transcript 3 (non-protein coding)	23	0.96
chr14_69419495_69419882	0.33	ACTN1	actinin, alpha 1	5423	0.25
chr12_78336681_78336916	0.33	NAV3	neuron navigator 3	23258	0.28
chr6_97386906_97387057	0.33	KLHL32	kelch-like family member 32	14229	0.2
chr6_156336017_156336168	0.33	ENSG00000221456	.	68161	0.14
chr8_67454441_67454873	0.33	ENSG00000206949	.	41111	0.13
chr7_142926484_142926635	0.33	AC073342.1	HCG2002387; Uncharacterized protein	7199	0.12
chr6_53357715_53357921	0.33	RP1-27K12.4		10165	0.18
chr14_52519313_52519627	0.33	NID2	nidogen 2 (osteonidogen)	13800	0.2
chr13_20175736_20176974	0.32	MPHOSPH8	M-phase phosphoprotein 8	31433	0.18
chr12_104233643_104233794	0.32	NT5DC3	5'-nucleotidase domain containing 3	1257	0.32
chr11_128778623_128778851	0.32	KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	2342	0.24
chr5_125460794_125460955	0.32	ENSG00000265637	.	71654	0.13
chr8_37310276_37310698	0.32	RP11-150O12.6		64052	0.13
chr7_25895792_25896027	0.32	ENSG00000199085	.	93697	0.09
chr8_85513931_85514082	0.32	ENSG00000206701	.	64094	0.14
chr5_121477747_121477957	0.32	ZNF474	zinc finger protein 474	12591	0.17
chr3_98619314_98619465	0.32	DCBLD2	discoidin, CUB and LCCL domain containing 2	626	0.66
chr14_89956186_89956636	0.32	FOXN3	forkhead box N3	3984	0.26
chr13_76213551_76213793	0.32	LMO7	LIM domain 7	3213	0.22
chr18_10454899_10455524	0.32	APCDD1	adenomatosis polyposis coli down-regulated 1	232	0.95
chr7_41734837_41734988	0.32	INHBA-AS1	INHBA antisense RNA 1	1366	0.45
chr18_12656814_12657797	0.32	SPIRE1	spire-type actin nucleation factor 1	570	0.5
chr13_24626733_24626884	0.32	SPATA13	spermatogenesis associated 13	72864	0.1
chr19_54483356_54483962	0.32	ENSG00000215998	.	1902	0.19
chr4_177484526_177484677	0.31	RP11-313E19.2		106171	0.07
chr15_61327175_61327382	0.31	RP11-39M21.1		146170	0.04
chr22_40894900_40895196	0.31	RP4-591N18.2		22756	0.15
chr2_36585229_36585663	0.31	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	1832	0.5
chr18_73688861_73689088	0.31	RP11-94B19.4	Uncharacterized protein	282147	0.01

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.4	GO:0072047	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.1	0.4	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1	0.8	GO:0001553	luteinization(GO:0001553)
0.1	0.4	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.2	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.5	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.5	GO:0008218	bioluminescence(GO:0008218)
0.1	0.3	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.2	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	0.2	GO:0060437	lung growth(GO:0060437)
0.1	0.3	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.4	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.1	0.3	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.3	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.1	0.3	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.2	GO:0051451	myoblast migration(GO:0051451)
0.1	0.6	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.2	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.1	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.1	0.3	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1	0.2	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1	0.2	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.3	GO:0051409	response to nitrosative stress(GO:0051409)
0.1	0.2	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.1	GO:0072338	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.5	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.1	0.7	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	0.4	GO:0016540	protein autoprocessing(GO:0016540)
0.1	0.4	GO:0031579	membrane raft organization(GO:0031579)
0.1	0.2	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	0.1	GO:0043931	ossification involved in bone maturation(GO:0043931)
0.1	0.1	GO:0060677	ureteric bud elongation(GO:0060677)
0.1	0.2	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1	0.1	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.1	0.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.4	GO:0060998	regulation of dendritic spine development(GO:0060998)
0.1	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.2	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.2	GO:0010107	potassium ion import(GO:0010107)
0.1	0.1	GO:0021831	embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.1	0.2	GO:0055022	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.3	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	1.0	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.8	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.0	0.2	GO:0001757	somite specification(GO:0001757)
0.0	0.7	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.2	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.1	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.2	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.4	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0060601	prostatic bud formation(GO:0060513) lateral sprouting from an epithelium(GO:0060601)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.0	GO:2000108	positive regulation of leukocyte apoptotic process(GO:2000108)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.2	GO:0060343	trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) trabecula morphogenesis(GO:0061383) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.3	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.3	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.0	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.0	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.3	GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0003181	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.2	GO:0021940	regulation of cerebellar granule cell precursor proliferation(GO:0021936) positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.2	GO:0032288	myelin assembly(GO:0032288)
0.0	0.0	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.3	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.1	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.1	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.3	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.2	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.2	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.1	GO:0051934	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.2	GO:0050746	regulation of lipoprotein metabolic process(GO:0050746)
0.0	0.1	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.2	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0010667	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.0	GO:0072070	loop of Henle development(GO:0072070)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.1	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.0	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.6	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.2	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.2	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.1	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.2	GO:0021988	olfactory lobe development(GO:0021988)
0.0	0.1	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.0	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.0	0.1	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.0	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.0	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	0.1	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.0	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	2.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.5	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.2	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.4	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.1	GO:0031427	response to methotrexate(GO:0031427)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.4	GO:0030901	midbrain development(GO:0030901)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.3	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.0	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.2	GO:0035136	forelimb morphogenesis(GO:0035136)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.0	GO:0030917	midbrain-hindbrain boundary morphogenesis(GO:0021555) midbrain-hindbrain boundary development(GO:0030917)
0.0	0.3	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.4	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:2000104	negative regulation of DNA-dependent DNA replication(GO:2000104)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0043324	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.1	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.0	GO:0070091	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0	0.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.0	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.0	GO:0015911	plasma membrane long-chain fatty acid transport(GO:0015911)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.4	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.2	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.1	GO:0031000	response to caffeine(GO:0031000)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.3	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.2	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.0	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0030501	positive regulation of bone mineralization(GO:0030501)
0.0	0.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.0	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.1	GO:0098743	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0007143	female meiotic division(GO:0007143)
0.0	0.0	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.3	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	0.0	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.3	GO:0042633	molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0	0.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.6	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.1	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.2	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.0	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.0	GO:0003078	obsolete regulation of natriuresis(GO:0003078) corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.0	GO:0009415	response to water(GO:0009415)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.1	GO:0030728	ovulation(GO:0030728)
0.0	0.0	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.1	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.0	GO:0032909	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.2	GO:0050773	regulation of dendrite development(GO:0050773)
0.0	0.0	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.0	GO:0032823	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.1	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.0	GO:1903318	negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0	0.0	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.2	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.0	GO:0070528	protein kinase C signaling(GO:0070528)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.0	GO:0031297	replication fork processing(GO:0031297)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.1	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.0	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0007617	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0	0.0	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.1	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.4	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.6	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.4	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.2	GO:0071437	invadopodium(GO:0071437)
0.1	0.3	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.7	GO:0008091	spectrin(GO:0008091)
0.1	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	0.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.3	GO:0043218	compact myelin(GO:0043218)
0.1	0.3	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.9	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.5	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.3	GO:0098644	complex of collagen trimers(GO:0098644)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.4	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	1.1	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.6	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.2	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.6	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.2	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.4	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.4	GO:0030018	Z disc(GO:0030018)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0044447	axoneme part(GO:0044447)
0.0	0.1	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.7	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	2.3	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.6	GO:0016459	myosin complex(GO:0016459)
0.0	0.2	GO:0005884	actin filament(GO:0005884)
0.0	0.2	GO:0030286	dynein complex(GO:0030286)
0.0	0.0	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.0	GO:0042599	lamellar body(GO:0042599)
0.0	0.0	GO:0045178	basal part of cell(GO:0045178)
0.0	0.0	GO:0042272	nuclear RNA export factor complex(GO:0042272)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.3	0.8	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2	0.6	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	0.5	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.4	GO:0016151	nickel cation binding(GO:0016151)
0.1	0.4	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.8	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.4	GO:0045545	syndecan binding(GO:0045545)
0.1	0.3	GO:0043559	insulin binding(GO:0043559)
0.1	0.4	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.3	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.3	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.3	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.3	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.3	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1	0.6	GO:0030507	spectrin binding(GO:0030507)
0.1	0.2	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.4	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.3	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.3	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	0.2	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.2	GO:0030172	troponin C binding(GO:0030172)
0.0	0.5	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.8	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.3	GO:0042805	actinin binding(GO:0042805)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	1.9	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.3	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.2	GO:0016595	glutamate binding(GO:0016595)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0045502	dynein binding(GO:0045502)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.5	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.2	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.0	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	1.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.3	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.0	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.0	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.0	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.2	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.0	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.0	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.0	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.3	GO:0070330	aromatase activity(GO:0070330)
0.0	0.1	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.0	GO:0005497	androgen binding(GO:0005497)
0.0	0.1	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.0	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.2	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.2	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.7	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	1.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.7	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.8	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	1.3	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	2.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.4	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.6	PID FGF PATHWAY	FGF signaling pathway
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.3	PID BMP PATHWAY	BMP receptor signaling
0.0	0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.3	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.0	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.7	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	0.6	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	0.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.6	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	1.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	1.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.0	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.4	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions