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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NFE2L1

Z-value: 1.76

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Transcription factors associated with NFE2L1

Gene Symbol	Gene ID	Gene Info
NFE2L1 Ensembl NCBI GeneCards UniProt	ENSG00000082641.11	NFE2L1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
NFE2L1	chr17_46125776_46126001	156	0.761365	-0.96	3.4e-05	Click!
NFE2L1	chr17_46128688_46128930	2315	0.142764	-0.77	1.6e-02	Click!
NFE2L1	chr17_46126176_46126433	158	0.853478	-0.66	5.5e-02	Click!
NFE2L1	chr17_46131994_46132145	3	0.949078	-0.64	6.5e-02	Click!
NFE2L1	chr17_46132310_46132461	103	0.927003	-0.62	7.7e-02	Click!

Activity of the NFE2L1 motif across conditions

Conditions sorted by the z-value of the NFE2L1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_70847938_70848765	0.38	SRGN	serglycin	477	0.82
chr1_81137024_81137175	0.37	ENSG00000266033	.	341926	0.01
chr8_5192496_5192647	0.35	ENSG00000242079	.	192342	0.03
chr9_91793130_91793737	0.35	SHC3	SHC (Src homology 2 domain containing) transforming protein 3	249	0.95
chr6_46702576_46703631	0.33	PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	24	0.97
chr2_41837870_41838465	0.33	ENSG00000221372	.	14641	0.29
chr15_58433367_58433518	0.31	ALDH1A2	aldehyde dehydrogenase 1 family, member A2	2418	0.3
chr16_50401597_50402736	0.31	RP11-21B23.1		325	0.64
chr17_80817564_80818630	0.30	TBCD	tubulin folding cofactor D	173	0.94
chr22_34240463_34240614	0.30	LARGE	like-glycosyltransferase	17074	0.25
chr1_65430726_65432146	0.30	JAK1	Janus kinase 1	751	0.73
chr6_111408575_111409679	0.30	SLC16A10	solute carrier family 16 (aromatic amino acid transporter), member 10	346	0.87
chr8_116470254_116470468	0.30	TRPS1	trichorhinophalangeal syndrome I	34087	0.22
chr3_147087748_147087899	0.29	RP11-649A16.1		620	0.73
chr10_135148565_135149526	0.29	CALY	calcyon neuron-specific vesicular protein	1331	0.22
chr6_138070872_138071097	0.29	ENSG00000216097	.	32899	0.17
chr18_52357258_52357685	0.29	RAB27B	RAB27B, member RAS oncogene family	27620	0.24
chr2_108443697_108444171	0.29	RGPD4	RANBP2-like and GRIP domain containing 4	541	0.87
chr14_30692792_30692943	0.28	PRKD1	protein kinase D1	31763	0.25
chr18_22869556_22869739	0.28	CTD-2006O16.2		12443	0.28
chr9_82226362_82226513	0.28	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	37833	0.24
chr3_177320979_177321130	0.28	ENSG00000200288	.	21143	0.27
chr3_38216440_38216633	0.28	OXSR1	oxidative stress responsive 1	9540	0.16
chr6_19465542_19465832	0.28	ENSG00000201523	.	27173	0.27
chr1_178095910_178096061	0.27	RASAL2	RAS protein activator like 2	32709	0.24
chr15_65578383_65579365	0.27	PARP16	poly (ADP-ribose) polymerase family, member 16	307	0.76
chr3_192549660_192549811	0.27	FGF12	fibroblast growth factor 12	64182	0.13
chr22_46988396_46988787	0.27	GRAMD4	GRAM domain containing 4	15565	0.21
chr1_65521422_65521573	0.27	ENSG00000265996	.	2028	0.29
chr4_72095290_72095441	0.27	SLC4A4	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	42321	0.21
chr6_125698814_125699135	0.26	RP11-735G4.1		3504	0.35
chr1_16490997_16491148	0.26	RP11-276H7.3		5311	0.12
chr5_72746479_72746692	0.26	FOXD1	forkhead box D1	2233	0.32
chr4_141852958_141853109	0.26	RNF150	ring finger protein 150	65157	0.13
chr7_105917980_105918131	0.25	NAMPT	nicotinamide phosphoribosyltransferase	7312	0.23
chr6_113529861_113530012	0.25	ENSG00000201386	.	237241	0.02
chr5_148139240_148139391	0.25	ADRB2	adrenoceptor beta 2, surface	66841	0.11
chr2_191914732_191914993	0.25	ENSG00000231858	.	28610	0.15
chr2_238596342_238596493	0.25	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	4371	0.26
chr4_129732983_129734245	0.25	JADE1	jade family PHD finger 1	615	0.83
chr1_79471738_79472138	0.25	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1	465	0.9
chr16_74440490_74441404	0.25	CLEC18B	C-type lectin domain family 18, member B	14343	0.14
chr2_201995461_201995643	0.24	CFLAR	CASP8 and FADD-like apoptosis regulator	963	0.45
chr2_10587541_10588176	0.24	ODC1	ornithine decarboxylase 1	48	0.95
chr6_35655029_35656564	0.24	FKBP5	FK506 binding protein 5	896	0.49
chr1_32732739_32732890	0.24	LCK	lymphocyte-specific protein tyrosine kinase	6900	0.09
chr5_66502810_66503002	0.24	CD180	CD180 molecule	10279	0.29
chr6_122253515_122253742	0.24	ENSG00000199932	.	279166	0.01
chr19_30205840_30206749	0.24	C19orf12	chromosome 19 open reading frame 12	133	0.97
chr16_70221940_70222878	0.24	CLEC18C	C-type lectin domain family 18, member C	14349	0.1
chr9_112955354_112955564	0.24	C9orf152	chromosome 9 open reading frame 152	15010	0.23
chr6_27521237_27521556	0.24	ENSG00000206671	.	42795	0.14
chr14_101034010_101035263	0.24	BEGAIN	brain-enriched guanylate kinase-associated	192	0.93
chr13_24146342_24146493	0.23	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1614	0.53
chr21_34602307_34603720	0.23	IFNAR2	interferon (alpha, beta and omega) receptor 2	299	0.87
chr1_14924992_14926197	0.23	KAZN	kazrin, periplakin interacting protein	381	0.93
chr13_50654211_50655703	0.23	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	1350	0.41
chr5_119432272_119432494	0.23	ENSG00000251975	.	240965	0.02
chr2_47425999_47426150	0.23	CALM2	calmodulin 2 (phosphorylase kinase, delta)	22334	0.19
chr17_73774322_73775453	0.23	H3F3B	H3 histone, family 3B (H3.3B)	480	0.64
chr2_133998912_133999202	0.23	AC010890.1		23483	0.24
chr20_20840805_20840956	0.23	ENSG00000264361	.	121506	0.06
chr16_57279074_57280095	0.23	ARL2BP	ADP-ribosylation factor-like 2 binding protein	296	0.82
chr8_17017795_17017946	0.23	ZDHHC2	zinc finger, DHHC-type containing 2	2438	0.36
chr17_47329713_47329864	0.23	PHOSPHO1	phosphatase, orphan 1	21660	0.13
chr1_169454193_169456202	0.23	SLC19A2	solute carrier family 19 (thiamine transporter), member 2	28	0.98
chr2_38299955_38300348	0.23	CYP1B1-AS1	CYP1B1 antisense RNA 1	2640	0.23
chr20_49138849_49139000	0.23	PTPN1	protein tyrosine phosphatase, non-receptor type 1	12004	0.16
chr8_15646506_15646657	0.23	TUSC3	tumor suppressor candidate 3	165992	0.04
chr7_157188129_157188280	0.23	DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	55689	0.14
chr17_55502106_55502257	0.23	ENSG00000263902	.	12619	0.26
chr20_3073179_3074190	0.23	ENSG00000263905	.	1177	0.34
chr12_27933175_27934389	0.23	KLHL42	kelch-like family member 42	18	0.73
chr5_55981802_55981953	0.22	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	79818	0.09
chr19_42306064_42306215	0.22	CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	5054	0.13
chr17_15280700_15281096	0.22	ENSG00000239888	.	30803	0.14
chr15_26041719_26041870	0.22	ENSG00000199214	.	21336	0.18
chr1_239995605_239995756	0.22	CHRM3-AS1	CHRM3 antisense RNA 1	67492	0.12
chr16_10679196_10679376	0.22	EMP2	epithelial membrane protein 2	4731	0.2
chr1_215183894_215184045	0.22	KCNK2	potassium channel, subfamily K, member 2	4771	0.37
chr9_110638127_110638278	0.22	ENSG00000222459	.	43057	0.16
chr6_35465033_35465928	0.22	TEAD3	TEA domain family member 3	627	0.7
chr8_32506055_32506353	0.22	NRG1	neuregulin 1	847	0.76
chr13_67804057_67805835	0.22	PCDH9	protocadherin 9	478	0.9
chr13_51483605_51485004	0.22	RNASEH2B	ribonuclease H2, subunit B	412	0.48
chr5_77805493_77806187	0.22	LHFPL2	lipoma HMGIC fusion partner-like 2	39134	0.21
chr4_47838472_47839750	0.22	CORIN	corin, serine peptidase	855	0.65
chr12_57527559_57527864	0.22	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	1789	0.2
chr5_73871785_73872054	0.22	HEXB	hexosaminidase B (beta polypeptide)	63929	0.12
chr15_23931247_23932124	0.22	NDN	necdin, melanoma antigen (MAGE) family member	765	0.7
chr15_99366225_99366435	0.21	ENSG00000264480	.	38675	0.17
chr19_19483852_19484190	0.21	GATAD2A	GATA zinc finger domain containing 2A	12614	0.13
chr5_39423074_39423254	0.21	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	1806	0.48
chr6_43139652_43140723	0.21	SRF	serum response factor (c-fos serum response element-binding transcription factor)	59	0.96
chr3_148366543_148366694	0.21	AGTR1	angiotensin II receptor, type 1	48953	0.18
chr3_175150286_175150526	0.21	ENSG00000199792	.	35269	0.2
chr13_24146543_24146694	0.21	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1815	0.49
chr2_99346083_99347252	0.21	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	44	0.98
chr4_1930205_1930356	0.21	WHSC1	Wolf-Hirschhorn syndrome candidate 1	11108	0.16
chr8_97536368_97536646	0.21	SDC2	syndecan 2	30271	0.22
chr6_45473095_45473246	0.21	RUNX2	runt-related transcription factor 2	82948	0.09
chr7_75986838_75988224	0.21	YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	817	0.59
chr9_130159461_130160475	0.21	SLC2A8	solute carrier family 2 (facilitated glucose transporter), member 8	305	0.87
chr1_100504063_100504968	0.21	HIAT1	hippocampus abundant transcript 1	862	0.51
chr16_67197260_67198336	0.21	HSF4	heat shock transcription factor 4	510	0.52
chr13_81010799_81010950	0.21	ENSG00000202398	.	67205	0.14
chrX_46838416_46838567	0.21	JADE3	jade family PHD finger 3	66260	0.09
chr3_43448035_43448186	0.21	SNRK-AS1	SNRK antisense RNA 1	54656	0.11
chr17_59235574_59235725	0.21	RP11-136H19.1		22324	0.2
chr20_11151199_11151404	0.21	C20orf187	chromosome 20 open reading frame 187	142490	0.05
chr2_177018526_177018677	0.21	HOXD4	homeobox D4	2651	0.11
chr11_28695349_28695500	0.21	ENSG00000222385	.	412358	0.01
chr8_67624599_67625774	0.21	SGK3	serum/glucocorticoid regulated kinase family, member 3	533	0.76
chr8_131960988_131961496	0.21	RP11-737F9.1		13587	0.24
chr17_53349481_53349632	0.21	RP11-515O17.2		1458	0.47
chr12_56075239_56075869	0.20	METTL7B	methyltransferase like 7B	224	0.86
chr3_36985452_36986747	0.20	TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	449	0.83
chr2_238358341_238358492	0.20	AC112721.1	Uncharacterized protein	24497	0.16
chrX_3629951_3631442	0.20	PRKX	protein kinase, X-linked	953	0.63
chr22_36608967_36609118	0.20	APOL4	apolipoprotein L, 4	8156	0.18
chr1_66713244_66713395	0.20	PDE4B	phosphodiesterase 4B, cAMP-specific	10011	0.3
chrX_118372691_118372845	0.20	PGRMC1	progesterone receptor membrane component 1	2480	0.36
chr6_7672125_7672276	0.20	BMP6	bone morphogenetic protein 6	54830	0.14
chr17_57920542_57920694	0.20	ENSG00000199004	.	1991	0.25
chr1_113045279_113045430	0.20	WNT2B	wingless-type MMTV integration site family, member 2B	6046	0.2
chr4_82585220_82585371	0.20	RASGEF1B	RasGEF domain family, member 1B	192226	0.03
chr3_87011295_87011446	0.20	VGLL3	vestigial like 3 (Drosophila)	28482	0.26
chr8_27200949_27201100	0.20	PTK2B	protein tyrosine kinase 2 beta	16684	0.2
chr13_42143466_42143617	0.20	ENSG00000264190	.	1010	0.64
chr7_24988449_24988600	0.20	OSBPL3	oxysterol binding protein-like 3	30812	0.21
chr10_129152577_129152728	0.20	FAM196A	family with sequence similarity 196, member A	158230	0.04
chr12_32261770_32262117	0.20	RP11-843B15.2		1481	0.38
chr4_79442125_79442276	0.20	ANXA3	annexin A3	30473	0.21
chr17_32582682_32583141	0.20	AC005549.3	Uncharacterized protein	605	0.41
chr8_23396205_23396870	0.20	SLC25A37	solute carrier family 25 (mitochondrial iron transporter), member 37	9964	0.16
chr4_24472696_24473642	0.20	ENSG00000265001	.	41714	0.15
chr14_24786486_24786637	0.20	LTB4R	leukotriene B4 receptor	2655	0.1
chr22_38928075_38928226	0.20	DDX17	DEAD (Asp-Glu-Ala-Asp) box helicase 17	25805	0.12
chr8_131020883_131021034	0.20	ENSG00000264653	.	259	0.91
chr8_142138821_142140144	0.20	RP11-809O17.1		578	0.46
chr1_217076565_217076716	0.20	ESRRG	estrogen-related receptor gamma	36372	0.24
chr12_114863083_114863234	0.20	TBX5-AS1	TBX5 antisense RNA 1	14064	0.21
chr12_20622316_20622467	0.20	RP11-284H19.1		99195	0.08
chr10_88159807_88161210	0.20	GRID1	glutamate receptor, ionotropic, delta 1	34273	0.17
chr3_194029323_194029474	0.20	CPN2	carboxypeptidase N, polypeptide 2	42649	0.14
chr7_18429816_18429967	0.19	AC010082.2		40470	0.19
chr2_216288358_216288696	0.19	FN1	fibronectin 1	12263	0.21
chr8_16995862_16996013	0.19	ZDHHC2	zinc finger, DHHC-type containing 2	17601	0.23
chr18_47017567_47018883	0.19	RPL17	ribosomal protein L17	15	0.51
chr2_71856946_71857097	0.19	DYSF	dysferlin	163189	0.04
chrX_44774522_44774719	0.19	ENSG00000252113	.	29869	0.19
chr10_7301046_7301197	0.19	SFMBT2	Scm-like with four mbt domains 2	149586	0.04
chr3_81772804_81773074	0.19	GBE1	glucan (1,4-alpha-), branching enzyme 1	19841	0.3
chr20_30457693_30458808	0.19	DUSP15	dual specificity phosphatase 15	125	0.67
chr21_38831523_38831674	0.19	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	29489	0.19
chr2_201978151_201978302	0.19	CFLAR	CASP8 and FADD-like apoptosis regulator	2601	0.2
chr3_120626761_120627590	0.19	STXBP5L	syntaxin binding protein 5-like	14	0.99
chr12_105114147_105114900	0.19	ENSG00000264295	.	129112	0.05
chr12_51636019_51636170	0.19	DAZAP2	DAZ associated protein 2	3015	0.18
chr4_184313441_184313592	0.19	ENSG00000263395	.	7810	0.18
chr6_2111373_2111600	0.19	GMDS	GDP-mannose 4,6-dehydratase	64739	0.15
chr9_96819103_96819334	0.19	PTPDC1	protein tyrosine phosphatase domain containing 1	26142	0.21
chr11_36641126_36641415	0.19	RAG2	recombination activating gene 2	21484	0.19
chrX_12929174_12929325	0.19	TLR8-AS1	TLR8 antisense RNA 1	2797	0.26
chr5_150181351_150181502	0.19	AC010441.1		23559	0.14
chr3_8152824_8153002	0.19	LMCD1-AS1	LMCD1 antisense RNA 1 (head to head)	94919	0.09
chr13_115028728_115028879	0.19	ENSG00000265450	.	10500	0.15
chr5_52106930_52107081	0.19	CTD-2288O8.1		23145	0.18
chr21_34392151_34392837	0.19	OLIG2	oligodendrocyte lineage transcription factor 2	5659	0.22
chr1_84107245_84107582	0.19	ENSG00000223231	.	152147	0.04
chr6_112555463_112555614	0.19	RP11-506B6.6		1756	0.35
chr18_56029142_56029527	0.19	RP11-845C23.2		9464	0.19
chr6_6546483_6547412	0.19	LY86-AS1	LY86 antisense RNA 1	40479	0.18
chr15_39882698_39882873	0.19	CTD-2033D15.1		3647	0.23
chr7_6292086_6292237	0.19	CYTH3	cytohesin 3	20114	0.16
chr11_12964003_12964154	0.19	RP11-47J17.2		19606	0.17
chr9_95525836_95526977	0.19	BICD2	bicaudal D homolog 2 (Drosophila)	688	0.71
chr21_40051384_40051625	0.19	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog	17800	0.28
chr1_59594796_59594947	0.19	FGGY	FGGY carbohydrate kinase domain containing	167439	0.04
chr7_7856053_7856204	0.19	RPA3-AS1	RPA3 antisense RNA 1	44136	0.16
chr4_134075824_134075975	0.19	PCDH10	protocadherin 10	5429	0.36
chr12_121340609_121341729	0.19	SPPL3	signal peptide peptidase like 3	4	0.98
chr10_102087281_102087432	0.19	PKD2L1	polycystic kidney disease 2-like 1	2373	0.21
chr6_138195405_138195556	0.19	RP11-356I2.4		6110	0.23
chr2_216546553_216546831	0.19	ENSG00000212055	.	196950	0.03
chr13_100647875_100648026	0.19	LINC00554	long intergenic non-protein coding RNA 554	2213	0.3
chr7_19034879_19035030	0.19	AC004744.3		95898	0.07
chr2_240302618_240303103	0.19	HDAC4	histone deacetylase 4	19783	0.17
chr5_17282488_17282863	0.19	ENSG00000252908	.	41955	0.15
chr2_68599888_68600039	0.18	AC015969.3		7247	0.18
chr17_13689465_13689699	0.18	ENSG00000236088	.	6285	0.33
chr16_87904899_87905050	0.18	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5	1880	0.31
chr18_43588722_43588960	0.18	ENSG00000222179	.	18930	0.17
chrX_49801111_49801262	0.18	ENSG00000272080	.	21980	0.08
chr4_40240364_40240515	0.18	RHOH	ras homolog family member H	38475	0.16
chr1_59221360_59221511	0.18	ENSG00000264081	.	9172	0.2
chr2_204394542_204394693	0.18	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	3539	0.35
chr7_38347403_38347554	0.18	STARD3NL	STARD3 N-terminal like	129481	0.05
chr3_161632795_161632946	0.18	OTOL1	otolin 1	418274	0.01
chr4_108745368_108745519	0.18	SGMS2	sphingomyelin synthase 2	276	0.93

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NFE2L1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.5	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.1	0.3	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.4	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.2	GO:0015801	aromatic amino acid transport(GO:0015801)
0.1	0.2	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.1	0.2	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.2	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.1	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.1	0.2	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.1	0.3	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.1	0.4	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.2	GO:0008049	male courtship behavior(GO:0008049)
0.1	0.2	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.2	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.2	GO:0060242	contact inhibition(GO:0060242)
0.1	0.2	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0033622	integrin activation(GO:0033622)
0.0	0.1	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.2	GO:2001259	activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0	0.0	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0051665	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.0	0.3	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.2	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0048840	otolith development(GO:0048840)
0.0	0.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0035930	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0	0.0	GO:0072033	renal vesicle formation(GO:0072033)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.0	GO:0061316	negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) canonical Wnt signaling pathway involved in heart development(GO:0061316) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.2	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.2	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.2	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.3	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.0	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.2	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.2	GO:0046184	aldehyde biosynthetic process(GO:0046184)
0.0	0.1	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.3	GO:0036296	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0071462	cellular response to water stimulus(GO:0071462)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.1	GO:0052169	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.0	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0050686	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.1	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.1	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0	0.1	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.1	GO:0071371	cellular response to gonadotropin stimulus(GO:0071371)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0034393	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.2	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.1	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.1	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0010664	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.2	GO:0046697	decidualization(GO:0046697)
0.0	0.0	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.3	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0061213	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:1903077	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.2	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.1	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.5	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.0	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.1	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.0	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.1	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0	0.0	GO:1903224	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.0	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.0	GO:0060677	ureteric bud elongation(GO:0060677)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0090177	establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0	0.0	GO:1901798	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.0	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.1	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0050955	sensory perception of temperature stimulus(GO:0050951) thermoception(GO:0050955)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.1	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.0	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.0	GO:0014010	Schwann cell proliferation(GO:0014010)
0.0	0.0	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.0	GO:0090103	cochlea morphogenesis(GO:0090103)
0.0	0.0	GO:0052572	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0010822	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0	0.0	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.0	GO:0048343	paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0010744	positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.0	0.0	GO:0003207	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.2	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.0	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	0.2	GO:1901663	quinone biosynthetic process(GO:1901663)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0010586	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.3	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.2	GO:0042401	cellular biogenic amine biosynthetic process(GO:0042401)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.0	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.0	0.0	GO:0070168	negative regulation of biomineral tissue development(GO:0070168)
0.0	0.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.0	GO:0070508	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0	0.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.0	GO:0042228	interleukin-8 biosynthetic process(GO:0042228)
0.0	0.1	GO:0032689	negative regulation of interferon-gamma production(GO:0032689)
0.0	0.3	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.0	GO:0070391	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.4	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0048668	collateral sprouting(GO:0048668)
0.0	0.0	GO:0072698	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.0	GO:0021794	thalamus development(GO:0021794)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0042554	superoxide anion generation(GO:0042554)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0019682	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.0	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
0.0	0.0	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.0	GO:0045056	transcytosis(GO:0045056)
0.0	0.0	GO:0051938	L-glutamate import(GO:0051938)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.0	GO:0019236	response to pheromone(GO:0019236)
0.0	0.0	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.0	GO:0043474	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0042181	ketone biosynthetic process(GO:0042181)
0.0	0.0	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.0	GO:0045830	positive regulation of isotype switching(GO:0045830)
0.0	0.0	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.0	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.0	GO:0034698	response to gonadotropin(GO:0034698)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:0032905	transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908)
0.0	0.0	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.0	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.0	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0021891	olfactory bulb interneuron development(GO:0021891)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0042629	mast cell granule(GO:0042629)
0.1	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.2	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.3	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0042597	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.3	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.6	GO:0005884	actin filament(GO:0005884)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.4	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.8	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.2	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0099738	cell cortex region(GO:0099738)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.2	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.0	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.0	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.2	GO:0005581	collagen trimer(GO:0005581)
0.0	0.0	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.3	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.2	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.3	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.3	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.2	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.2	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.2	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.3	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.2	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.0	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.3	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.2	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.0	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.3	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.6	GO:0005518	collagen binding(GO:0005518)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.0	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.0	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.3	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.0	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0019841	retinol binding(GO:0019841)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.4	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.2	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.2	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.0	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.0	GO:0016503	pheromone receptor activity(GO:0016503)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.0	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.0	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.2	GO:0004364	glutathione transferase activity(GO:0004364)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	0.1	PID MYC PATHWAY	C-MYC pathway
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.6	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.5	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.3	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.1	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.2	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID EPHA FWDPATHWAY	EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.4	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.5	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.3	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.4	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines