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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for NFIL3

Z-value: 1.81

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Transcription factors associated with NFIL3

Gene Symbol	Gene ID	Gene Info
NFIL3 Ensembl NCBI GeneCards UniProt	ENSG00000165030.3	nuclear factor, interleukin 3 regulated

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr9_94178166_94178317	NFIL3	7903	0.290233	0.87	2.0e-03	Click!
chr9_94181355_94181506	NFIL3	4714	0.319979	0.87	2.2e-03	Click!
chr9_94190929_94191080	NFIL3	4860	0.323487	0.83	5.3e-03	Click!
chr9_94172840_94172991	NFIL3	13229	0.268883	0.82	6.2e-03	Click!
chr9_94173775_94173926	NFIL3	12294	0.272118	0.82	6.7e-03	Click!

Activity of the NFIL3 motif across conditions

Conditions sorted by the z-value of the NFIL3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_133022737_133022888	0.97	MUC8	mucin 8	27914	0.17
chr10_74572337_74572942	0.92	RP11-354E23.5		46321	0.13
chr2_28939308_28939670	0.81	AC097724.3		19486	0.15
chr7_28725956_28726399	0.81	CREB5	cAMP responsive element binding protein 5	579	0.86
chr2_28619412_28619563	0.76	RP11-373D23.2		195	0.87
chr6_7201850_7202136	0.74	ENSG00000201483	.	14074	0.19
chr1_4999527_4999744	0.74	AJAP1	adherens junctions associated protein 1	284530	0.01
chr12_11809211_11809577	0.68	ETV6	ets variant 6	6606	0.29
chr11_59950051_59950297	0.67	MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	325	0.9
chr3_172280513_172281223	0.62	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	39571	0.16
chr2_70750715_70751050	0.61	TGFA	transforming growth factor, alpha	29740	0.17
chr11_118109635_118109786	0.61	MPZL3	myelin protein zero-like 3	13352	0.13
chr8_25058747_25058898	0.58	DOCK5	dedicator of cytokinesis 5	16442	0.23
chr2_210390663_210390935	0.58	MAP2	microtubule-associated protein 2	53240	0.18
chr17_68166405_68166607	0.57	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2	830	0.45
chrX_45634159_45634477	0.57	ENSG00000207725	.	27788	0.21
chr4_144258321_144259298	0.57	GAB1	GRB2-associated binding protein 1	478	0.81
chr15_55696104_55696525	0.56	CCPG1	cell cycle progression 1	3936	0.2
chr11_77185235_77185792	0.55	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	167	0.92
chr22_31631160_31631361	0.55	ENSG00000202019	.	5102	0.12
chr10_17257961_17258251	0.54	VIM-AS1	VIM antisense RNA 1	10791	0.15
chr22_19874685_19874970	0.54	GNB1L	guanine nucleotide binding protein (G protein), beta polypeptide 1-like	32365	0.11
chr2_86667455_86667782	0.54	KDM3A	lysine (K)-specific demethylase 3A	152	0.96
chr15_93351259_93351410	0.54	CTD-2313J17.1		463	0.75
chr3_171779467_171780048	0.53	FNDC3B	fibronectin type III domain containing 3B	15054	0.27
chr20_10286915_10287750	0.53	ENSG00000211588	.	55546	0.13
chr12_27296518_27296946	0.53	C12orf71	chromosome 12 open reading frame 71	61285	0.12
chr3_186633899_186634165	0.53	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	14242	0.17
chr12_120755596_120755815	0.52	ENSG00000252659	.	4561	0.12
chr20_43525395_43525569	0.51	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	11089	0.14
chr10_51575835_51576189	0.51	NCOA4	nuclear receptor coactivator 4	273	0.91
chr14_104399423_104399760	0.50	TDRD9	tudor domain containing 9	4774	0.16
chr5_156985680_156985923	0.50	AC106801.1		7171	0.17
chr6_144357186_144358268	0.50	PLAGL1	pleiomorphic adenoma gene-like 1	28008	0.21
chr15_32810260_32810411	0.50	AC135983.2	Protein LOC100996413	35513	0.11
chr16_19524952_19525190	0.50	GDE1	glycerophosphodiester phosphodiesterase 1	3419	0.15
chr9_94184850_94185394	0.49	NFIL3	nuclear factor, interleukin 3 regulated	1022	0.67
chr18_77586592_77586743	0.49	KCNG2	potassium voltage-gated channel, subfamily G, member 2	37001	0.19
chr1_153365062_153365349	0.48	S100A8	S100 calcium binding protein A8	1541	0.25
chr17_80189068_80189889	0.47	SLC16A3	solute carrier family 16 (monocarboxylate transporter), member 3	630	0.57
chr10_440428_440579	0.47	DIP2C	DIP2 disco-interacting protein 2 homolog C (Drosophila)	6754	0.22
chr5_88120627_88121096	0.47	MEF2C	myocyte enhancer factor 2C	704	0.78
chr4_13615018_13615169	0.46	BOD1L1	biorientation of chromosomes in cell division 1-like 1	14254	0.19
chr9_127024548_127024933	0.46	RP11-121A14.3		415	0.67
chr2_160471179_160471674	0.46	AC009506.1		381	0.66
chr2_226983216_226983814	0.46	ENSG00000263363	.	539994	0.0
chr4_154450958_154451109	0.46	KIAA0922	KIAA0922	26015	0.22
chr13_48736574_48736800	0.46	MED4	mediator complex subunit 4	67420	0.1
chr3_15358347_15358781	0.46	ENSG00000238891	.	437	0.79
chr22_44568627_44569086	0.46	PARVG	parvin, gamma	20	0.99
chr17_28037574_28037864	0.45	RP11-82O19.1		50402	0.08
chr4_121737778_121738146	0.45	ENSG00000212359	.	6338	0.32
chr3_157154723_157155399	0.45	PTX3	pentraxin 3, long	483	0.86
chr10_3511186_3511467	0.45	RP11-184A2.3		281933	0.01
chr9_70850276_70850542	0.45	CBWD3	COBW domain containing 3	5988	0.18
chr22_22417650_22417801	0.45	IGLVV-66	immunoglobulin lambda variable (V)-66 (pseudogene)	2236	0.12
chr2_26214629_26214790	0.44	KIF3C	kinesin family member 3C	9091	0.19
chr17_57786557_57786708	0.44	VMP1	vacuole membrane protein 1	1549	0.29
chr17_56744273_56744616	0.44	ENSG00000199426	.	386	0.76
chr4_15661278_15661429	0.44	FBXL5	F-box and leucine-rich repeat protein 5	134	0.96
chr19_47814050_47814201	0.44	C5AR1	complement component 5a receptor 1	994	0.46
chr14_89769991_89770787	0.44	RP11-356K23.1		46240	0.14
chr1_159061998_159062403	0.43	AIM2	absent in melanoma 2	15509	0.17
chr9_40632604_40633916	0.43	SPATA31A3	SPATA31 subfamily A, member 3	67031	0.14
chr4_74606139_74606524	0.43	IL8	interleukin 8	73	0.98
chr9_77501796_77502826	0.43	TRPM6	transient receptor potential cation channel, subfamily M, member 6	48	0.97
chr3_128207705_128209147	0.43	RP11-475N22.4		326	0.79
chr17_19289644_19289962	0.42	MFAP4	microfibrillar-associated protein 4	442	0.7
chr19_58630342_58630493	0.42	ZSCAN18	zinc finger and SCAN domain containing 18	623	0.64
chr10_51574545_51574696	0.42	NCOA4	nuclear receptor coactivator 4	1320	0.42
chr2_60783649_60784435	0.41	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	3340	0.31
chr9_126628860_126629011	0.41	DENND1A	DENN/MADD domain containing 1A	63451	0.12
chr7_26413797_26413948	0.41	AC004540.4		2020	0.37
chr5_147566124_147566390	0.41	SPINK6	serine peptidase inhibitor, Kazal type 6	16100	0.18
chr12_29311473_29311703	0.41	FAR2	fatty acyl CoA reductase 2	9455	0.26
chr1_183555866_183556017	0.41	NCF2	neutrophil cytosolic factor 2	3775	0.24
chr6_134551187_134551338	0.41	ENSG00000238631	.	23610	0.16
chr7_76968350_76968501	0.41	GSAP	gamma-secretase activating protein	8741	0.25
chrX_18686331_18686482	0.41	RS1	retinoschisin 1	3823	0.25
chr17_65430092_65430384	0.40	ENSG00000244610	.	23168	0.12
chr7_128048882_128049033	0.40	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1	998	0.47
chr1_38317055_38317206	0.40	MTF1	metal-regulatory transcription factor 1	8162	0.1
chr14_70169504_70169749	0.40	SRSF5	serine/arginine-rich splicing factor 5	23991	0.21
chr7_33088447_33088598	0.40	ENSG00000241420	.	2820	0.22
chr9_128521797_128522422	0.40	PBX3	pre-B-cell leukemia homeobox 3	11631	0.27
chr7_28725630_28725928	0.40	CREB5	cAMP responsive element binding protein 5	181	0.97
chr3_150608248_150608399	0.40	RP11-166N6.2		100	0.87
chr4_141348226_141349120	0.40	CLGN	calmegin	91	0.97
chr19_35940642_35940793	0.40	FFAR2	free fatty acid receptor 2	100	0.95
chr8_74792407_74792558	0.40	UBE2W	ubiquitin-conjugating enzyme E2W (putative)	1337	0.48
chr9_65576390_65577630	0.40	SPATA31A7	SPATA31 subfamily A, member 7	67400	0.15
chr13_20535826_20536004	0.40	ZMYM2	zinc finger, MYM-type 2	2992	0.28
chr3_156423919_156424189	0.40	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase	25099	0.2
chr19_18475720_18476136	0.39	PGPEP1	pyroglutamyl-peptidase I	7612	0.09
chr9_21023989_21024197	0.39	PTPLAD2	protein tyrosine phosphatase-like A domain containing 2	7515	0.22
chr6_13273042_13273413	0.39	PHACTR1	phosphatase and actin regulator 1	238	0.88
chr2_167231853_167232143	0.39	SCN9A	sodium channel, voltage-gated, type IX, alpha subunit	499	0.84
chr11_64647105_64647256	0.39	EHD1	EH-domain containing 1	8	0.95
chr21_37572436_37572587	0.39	ENSG00000265882	.	13625	0.14
chr1_246378930_246379130	0.39	SMYD3	SET and MYND domain containing 3	22001	0.2
chr2_64501475_64501626	0.39	AC074289.1		45948	0.16
chr9_12859535_12860149	0.39	ENSG00000222658	.	25478	0.2
chr15_91955379_91955670	0.38	SV2B	synaptic vesicle glycoprotein 2B	186424	0.03
chr1_68149030_68149645	0.38	GADD45A	growth arrest and DNA-damage-inducible, alpha	1407	0.47
chr8_12615101_12615641	0.38	LONRF1	LON peptidase N-terminal domain and ring finger 1	2372	0.31
chr20_45946936_45948261	0.38	AL031666.2	HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852	352	0.82
chr7_87987383_87987655	0.38	STEAP4	STEAP family member 4	51313	0.14
chr12_42775990_42776141	0.38	ENSG00000199886	.	16287	0.15
chr12_10180419_10180570	0.38	RP11-133L14.5		2711	0.16
chrX_24043946_24044693	0.38	KLHL15	kelch-like family member 15	984	0.59
chr1_233249017_233249707	0.38	PCNXL2	pecanex-like 2 (Drosophila)	46691	0.19
chr12_70132575_70133879	0.38	RAB3IP	RAB3A interacting protein	47	0.95
chr3_185677710_185678274	0.38	RP11-443P15.2		164	0.95
chr2_175190619_175190960	0.38	SP9	Sp9 transcription factor	8885	0.17
chr14_95652514_95652665	0.38	CTD-2240H23.2		398	0.82
chr11_10480131_10480282	0.38	AMPD3	adenosine monophosphate deaminase 3	2473	0.29
chr6_7698531_7698719	0.38	BMP6	bone morphogenetic protein 6	28405	0.23
chr8_38264898_38265049	0.38	RP11-350N15.6		1287	0.31
chr10_119129819_119130103	0.38	PDZD8	PDZ domain containing 8	5017	0.24
chr9_89364915_89365206	0.38	GAS1	growth arrest-specific 1	197044	0.03
chr7_77039376_77039559	0.37	GSAP	gamma-secretase activating protein	5717	0.24
chr2_61023542_61023744	0.37	PAPOLG	poly(A) polymerase gamma	14533	0.2
chr10_3507816_3508043	0.37	RP11-184A2.3		285330	0.01
chr9_101871702_101872013	0.37	TGFBR1	transforming growth factor, beta receptor 1	4425	0.25
chr9_139117671_139117822	0.37	QSOX2	quiescin Q6 sulfhydryl oxidase 2	1023	0.52
chrX_135848105_135848417	0.37	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	1241	0.45
chr5_94417062_94417734	0.37	MCTP1	multiple C2 domains, transmembrane 1	48	0.99
chr22_37350353_37350504	0.37	ENSG00000239056	.	5906	0.13
chr14_73928931_73929214	0.37	ENSG00000251393	.	57	0.97
chr1_209846224_209846375	0.37	RP1-28O10.1		2293	0.2
chr2_99346083_99347252	0.37	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	44	0.98
chr21_44525173_44525376	0.37	U2AF1	U2 small nuclear RNA auxiliary factor 1	88	0.96
chr17_67497729_67497946	0.37	MAP2K6	mitogen-activated protein kinase kinase 6	458	0.9
chr3_152787896_152788047	0.37	RP11-529G21.2		91593	0.08
chr2_179395534_179395685	0.37	TTN-AS1	TTN antisense RNA 1	67	0.96
chr1_210412971_210413268	0.37	SERTAD4-AS1	SERTAD4 antisense RNA 1	5727	0.24
chr20_30625571_30625821	0.37	RP1-310O13.7		6318	0.12
chr13_76259054_76259476	0.37	LMO7	LIM domain 7	48806	0.13
chr2_207998546_207999225	0.36	KLF7	Kruppel-like factor 7 (ubiquitous)	24	0.98
chr7_77314536_77314687	0.36	RSBN1L	round spermatid basic protein 1-like	11149	0.25
chr15_90368391_90368542	0.36	ANPEP	alanyl (membrane) aminopeptidase	9833	0.12
chr4_176867859_176868338	0.36	GPM6A	glycoprotein M6A	24000	0.23
chr7_75535458_75535737	0.36	POR	P450 (cytochrome) oxidoreductase	1297	0.38
chr8_23396205_23396870	0.36	SLC25A37	solute carrier family 25 (mitochondrial iron transporter), member 37	9964	0.16
chr1_41575455_41576018	0.36	SCMH1	sex comb on midleg homolog 1 (Drosophila)	49869	0.15
chr11_94473290_94474384	0.36	RP11-867G2.8		316	0.92
chr17_73972138_73972317	0.36	ACOX1	acyl-CoA oxidase 1, palmitoyl	2547	0.14
chr1_66839254_66839405	0.36	PDE4B	phosphodiesterase 4B, cAMP-specific	19264	0.27
chr11_63639674_63640171	0.36	MARK2	MAP/microtubule affinity-regulating kinase 2	3174	0.18
chr9_123455609_123455760	0.36	MEGF9	multiple EGF-like-domains 9	20928	0.23
chr15_99091192_99092106	0.36	FAM169B	family with sequence similarity 169, member B	34038	0.21
chr11_94307505_94307715	0.36	PIWIL4	piwi-like RNA-mediated gene silencing 4	6753	0.2
chr7_111720888_111721301	0.36	DOCK4	dedicator of cytokinesis 4	76908	0.11
chr13_77454298_77454449	0.36	KCTD12	potassium channel tetramerization domain containing 12	6152	0.22
chr2_74765980_74766272	0.35	HTRA2	HtrA serine peptidase 2	8953	0.07
chr16_9193995_9194146	0.35	RP11-473I1.9		4635	0.17
chr20_354312_354573	0.35	TRIB3	tribbles pseudokinase 3	6819	0.14
chr2_176971683_176972255	0.35	HOXD11	homeobox D11	45	0.92
chr12_65032414_65032565	0.35	RP11-338E21.2		10365	0.12
chr12_106699376_106699527	0.35	CKAP4	cytoskeleton-associated protein 4	1394	0.34
chr3_112277196_112277347	0.35	SLC35A5	solute carrier family 35, member A5	3285	0.23
chr8_17017795_17017946	0.35	ZDHHC2	zinc finger, DHHC-type containing 2	2438	0.36
chr1_33812503_33812654	0.35	PHC2	polyhomeotic homolog 2 (Drosophila)	2908	0.16
chr1_186649638_186650434	0.35	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	477	0.89
chr17_60905052_60905372	0.35	MARCH10	membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase	19507	0.23
chr12_123376332_123377156	0.34	VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)	2038	0.29
chr5_16509247_16509418	0.34	FAM134B	family with sequence similarity 134, member B	225	0.95
chr3_58320901_58321052	0.34	PXK	PX domain containing serine/threonine kinase	1943	0.34
chr4_170928374_170928525	0.34	MFAP3L	microfibrillar-associated protein 3-like	323	0.91
chr19_12637235_12637523	0.34	CTD-2192J16.21		6408	0.12
chr2_40786004_40786155	0.34	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1	46504	0.21
chr6_56573707_56573932	0.34	DST	dystonin	66025	0.13
chr10_119795150_119795373	0.34	RP11-354M20.3		3987	0.24
chr15_86099150_86099301	0.34	AKAP13	A kinase (PRKA) anchor protein 13	548	0.77
chr15_40530958_40531718	0.34	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	46	0.96
chr17_592967_593118	0.34	VPS53	vacuolar protein sorting 53 homolog (S. cerevisiae)	24907	0.15
chr18_18744174_18744617	0.34	ENSG00000251886	.	43928	0.15
chr1_152022639_152022790	0.34	S100A11	S100 calcium binding protein A11	13203	0.14
chr3_146260050_146260212	0.34	PLSCR1	phospholipid scramblase 1	2177	0.31
chr12_54018588_54018739	0.34	ATF7	activating transcription factor 7	1092	0.33
chr17_80358251_80358402	0.34	RP13-20L14.4		932	0.35
chr7_139561657_139561808	0.34	TBXAS1	thromboxane A synthase 1 (platelet)	32622	0.21
chr8_22961570_22961743	0.34	TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	1222	0.37
chr8_48438743_48438894	0.33	RP11-697N18.4		1141	0.63
chr7_112093389_112093943	0.33	IFRD1	interferon-related developmental regulator 1	1194	0.53
chr9_101870409_101870560	0.33	TGFBR1	transforming growth factor, beta receptor 1	3052	0.29
chr7_104854367_104854518	0.33	SRPK2	SRSF protein kinase 2	55020	0.13
chr7_993167_993948	0.33	ADAP1	ArfGAP with dual PH domains 1	776	0.55
chr18_74187546_74187838	0.33	ZNF516	zinc finger protein 516	15043	0.17
chr2_74804249_74804525	0.33	LOXL3	lysyl oxidase-like 3	21570	0.09
chr6_152897054_152897205	0.33	RP11-133I21.2		30061	0.19
chr11_59949160_59949311	0.33	MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	96	0.97
chr10_27148230_27149879	0.33	ABI1	abl-interactor 1	738	0.67
chr9_107826629_107826909	0.33	ENSG00000201583	.	32268	0.22
chr7_141689032_141689183	0.33	MGAM	maltase-glucoamylase (alpha-glucosidase)	6531	0.17
chr5_72921316_72921781	0.33	ARHGEF28	Rho guanine nucleotide exchange factor (GEF) 28	435	0.84
chr1_78757040_78757336	0.33	PTGFR	prostaglandin F receptor (FP)	12380	0.24
chr19_50862163_50862314	0.33	NAPSA	napsin A aspartic peptidase	6644	0.09
chr6_147234783_147235185	0.33	STXBP5-AS1	STXBP5 antisense RNA 1	2037	0.48
chr11_3887299_3887491	0.33	STIM1	stromal interaction molecule 1	938	0.41

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIL3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:2001280	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2	0.5	GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.1	0.4	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.5	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1	0.7	GO:0002634	regulation of germinal center formation(GO:0002634)
0.1	0.4	GO:0010193	response to ozone(GO:0010193)
0.1	0.9	GO:0046184	aldehyde biosynthetic process(GO:0046184)
0.1	0.5	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.1	0.3	GO:0071436	sodium ion export(GO:0071436)
0.1	0.7	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.6	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.3	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.4	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.3	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1	0.5	GO:0001878	response to yeast(GO:0001878)
0.1	0.3	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	0.3	GO:0001779	natural killer cell differentiation(GO:0001779)
0.1	0.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.4	GO:0030321	transepithelial chloride transport(GO:0030321)
0.1	0.3	GO:0044320	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.1	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.3	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.6	GO:0045830	positive regulation of isotype switching(GO:0045830)
0.1	0.2	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.3	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.2	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.2	GO:0003171	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.1	0.2	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.4	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.1	0.5	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.2	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.1	0.2	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.4	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.1	0.3	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.3	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.3	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1	0.2	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.4	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.1	0.1	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.1	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1	0.3	GO:0010885	regulation of cholesterol storage(GO:0010885)
0.1	0.3	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.1	0.1	GO:1903170	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1	0.2	GO:0006177	GMP biosynthetic process(GO:0006177)
0.1	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.8	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	0.3	GO:0008354	germ cell migration(GO:0008354)
0.1	0.2	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.1	0.2	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1	0.1	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1	0.2	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.1	0.2	GO:0006565	L-serine catabolic process(GO:0006565)
0.1	0.3	GO:0009649	entrainment of circadian clock(GO:0009649)
0.1	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.1	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.1	0.2	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	0.1	GO:1903960	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.2	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.0	GO:0010878	cholesterol storage(GO:0010878)
0.0	0.3	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.2	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.2	GO:0032667	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0	0.0	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0	0.3	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.2	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.0	0.5	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.2	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.2	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.2	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.2	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.2	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.3	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0051136	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.0	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0	0.2	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0	0.2	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.2	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.2	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.0	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.1	GO:2000846	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0	0.2	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.2	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.2	GO:0060251	regulation of glial cell proliferation(GO:0060251)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.2	GO:0043584	nose development(GO:0043584)
0.0	0.0	GO:0033622	integrin activation(GO:0033622)
0.0	0.2	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.2	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.2	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.5	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0055094	response to lipoprotein particle(GO:0055094)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.1	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.4	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0031054	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) pre-miRNA processing(GO:0031054)
0.0	0.1	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.2	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.3	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0	0.4	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	0.1	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.4	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.2	GO:0006911	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.2	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.2	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.2	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.1	GO:0006837	serotonin transport(GO:0006837)
0.0	0.1	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.5	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.3	GO:0008210	estrogen metabolic process(GO:0008210)
0.0	0.2	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.0	GO:0071803	podosome assembly(GO:0071800) regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.1	GO:0060039	pericardium development(GO:0060039)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.4	GO:0007620	copulation(GO:0007620)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0070431	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.0	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.3	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
0.0	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.0	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.1	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.0	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.0	GO:0060004	reflex(GO:0060004)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.3	GO:0090181	regulation of cholesterol metabolic process(GO:0090181)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.2	GO:0036296	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.1	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0055057	forebrain neuroblast division(GO:0021873) neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.1	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.6	GO:0048813	dendrite morphogenesis(GO:0048813)
0.0	0.1	GO:0045408	regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.2	GO:0006265	DNA topological change(GO:0006265)
0.0	0.0	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0050802	circadian sleep/wake cycle process(GO:0022410) circadian sleep/wake cycle, sleep(GO:0050802)
0.0	0.1	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.0	GO:0019240	citrulline biosynthetic process(GO:0019240)
0.0	0.0	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0045655	regulation of monocyte differentiation(GO:0045655)
0.0	0.2	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.1	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.3	GO:0044247	glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.0	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0002921	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.2	GO:0046135	pyrimidine nucleoside catabolic process(GO:0046135)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0090196	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0015695	organic cation transport(GO:0015695)
0.0	0.1	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.0	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.0	GO:0042747	circadian sleep/wake cycle, REM sleep(GO:0042747)
0.0	0.0	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.0	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.0	GO:0032328	alanine transport(GO:0032328)
0.0	0.0	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.4	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0032222	regulation of synaptic transmission, cholinergic(GO:0032222)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.2	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0002830	positive regulation of type 2 immune response(GO:0002830)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.3	GO:0035338	long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0	0.0	GO:0070100	regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0042891	antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.0	0.2	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0042363	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.1	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.0	GO:1903392	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0	0.2	GO:0001569	patterning of blood vessels(GO:0001569)
0.0	0.0	GO:0031622	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.0	GO:0032373	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0	0.2	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.0	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.1	GO:0051900	regulation of membrane depolarization(GO:0003254) regulation of mitochondrial depolarization(GO:0051900)
0.0	0.0	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.0	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:0009180	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.0	GO:0045007	depurination(GO:0045007)
0.0	0.0	GO:0048596	embryonic camera-type eye morphogenesis(GO:0048596)
0.0	0.0	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.0	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.0	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.2	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.3	GO:0001756	somitogenesis(GO:0001756)
0.0	0.0	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.3	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0007625	grooming behavior(GO:0007625)
0.0	0.0	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.4	GO:0019233	sensory perception of pain(GO:0019233)
0.0	0.0	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.0	GO:0032847	regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849)
0.0	0.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.0	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.2	GO:0030593	neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0	0.0	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0061430	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.2	GO:0007032	endosome organization(GO:0007032)
0.0	0.0	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0048538	thymus development(GO:0048538)
0.0	0.0	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.0	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.0	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.1	GO:0015791	polyol transport(GO:0015791)
0.0	0.0	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.4	GO:0015718	monocarboxylic acid transport(GO:0015718)
0.0	0.0	GO:0042752	regulation of circadian rhythm(GO:0042752)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0009744	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.1	GO:0030194	positive regulation of blood coagulation(GO:0030194) positive regulation of hemostasis(GO:1900048)
0.0	0.2	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.0	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.0	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.0	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.3	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.0	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.0	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.0	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.1	GO:0006693	prostaglandin metabolic process(GO:0006693)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.1	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.1	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.5	GO:0001527	microfibril(GO:0001527)
0.1	0.2	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.3	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.5	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.2	GO:0071547	piP-body(GO:0071547)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.2	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.7	GO:0000421	autophagosome membrane(GO:0000421)
0.1	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.2	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.4	GO:0042588	zymogen granule(GO:0042588)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.3	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.3	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.2	GO:0099738	cell cortex region(GO:0099738)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.2	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.4	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.3	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.7	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.4	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.3	GO:0031526	brush border membrane(GO:0031526)
0.0	0.0	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.4	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.4	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.3	GO:0070052	collagen V binding(GO:0070052)
0.1	0.5	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1	0.3	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.5	GO:0032052	bile acid binding(GO:0032052)
0.1	0.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.5	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.5	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1	0.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.5	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1	0.7	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.3	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.4	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	0.2	GO:0031849	olfactory receptor binding(GO:0031849)
0.1	0.4	GO:0030955	potassium ion binding(GO:0030955)
0.1	0.4	GO:0001846	opsonin binding(GO:0001846)
0.1	0.8	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	0.3	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.3	GO:0004340	glucokinase activity(GO:0004340)
0.1	0.2	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.3	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.1	0.3	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.4	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.2	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	0.4	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	0.2	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	0.2	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.2	GO:0016972	thiol oxidase activity(GO:0016972)
0.1	0.4	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.4	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.3	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.2	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.1	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.7	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0033265	choline binding(GO:0033265)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.4	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.4	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.5	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.7	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.2	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.3	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0042806	fucose binding(GO:0042806)
0.0	1.1	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.5	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.2	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.2	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	1.1	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.3	GO:0019894	kinesin binding(GO:0019894)
0.0	0.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.3	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	1.1	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.4	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.0	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.5	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.3	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.0	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.0	GO:0003916	DNA topoisomerase activity(GO:0003916)
0.0	0.0	GO:0004739	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.3	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.0	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.0	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	1.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.0	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.2	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.4	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.0	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.4	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.0	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.0	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.1	GO:0015197	peptide transporter activity(GO:0015197)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.0	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.0	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0019841	retinol binding(GO:0019841)
0.0	0.5	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.0	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	1.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	1.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	1.3	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.6	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.5	ST ADRENERGIC	Adrenergic Pathway
0.0	1.9	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.6	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.5	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.4	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.0	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.2	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.5	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.0	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	1.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	0.2	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.1	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	0.4	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	1.1	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.6	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	1.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.2	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.6	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.8	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.5	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.1	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.5	REACTOME PURINE METABOLISM	Genes involved in Purine metabolism
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.2	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.0	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.8	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.1	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.0	0.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.1	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.3	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins

Results for NFIL3

Z-value: 1.81

Motif logo

Transcription factors associated with NFIL3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the NFIL3 motif across conditions

Conditions sorted by the z-value of the NFIL3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIL3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: