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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for NFIX_NFIB

Z-value: 7.51

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Transcription factors associated with NFIX_NFIB

Gene Symbol	Gene ID	Gene Info
NFIX Ensembl NCBI GeneCards UniProt	ENSG00000008441.12	nuclear factor I X
NFIB Ensembl NCBI GeneCards UniProt	ENSG00000147862.10	nuclear factor I B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr9_14096707_14097036	NFIB	83920	0.111989	0.96	3.7e-05	Click!
chr9_14096297_14096607	NFIB	84339	0.111268	0.94	1.5e-04	Click!
chr9_14309575_14309740	NFIB	1645	0.458203	0.93	2.2e-04	Click!
chr9_14251177_14251439	NFIB	56704	0.153396	0.93	2.3e-04	Click!
chr9_14312403_14312554	NFIB	1188	0.558006	0.91	6.4e-04	Click!
chr19_13135354_13135619	NFIX	45	0.951685	0.90	8.5e-04	Click!
chr19_13135793_13135990	NFIX	80	0.943717	0.89	1.4e-03	Click!
chr19_13135028_13135217	NFIX	272	0.835446	0.88	1.5e-03	Click!
chr19_13137554_13137705	NFIX	1818	0.202683	0.87	2.0e-03	Click!
chr19_13136060_13136211	NFIX	324	0.795470	0.87	2.3e-03	Click!

Activity of the NFIX_NFIB motif across conditions

Conditions sorted by the z-value of the NFIX_NFIB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_158113918_158114875	5.04	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	286	0.93
chr16_4366907_4367444	4.33	GLIS2	GLIS family zinc finger 2	2413	0.21
chr15_51633704_51634417	4.30	GLDN	gliomedin	234	0.91
chr17_70587270_70588900	4.12	ENSG00000200783	.	72206	0.12
chr4_157891142_157892336	4.10	PDGFC	platelet derived growth factor C	316	0.91
chr9_104248314_104249564	4.08	TMEM246	transmembrane protein 246	460	0.79
chr7_134464463_134465343	4.07	CALD1	caldesmon 1	474	0.89
chr3_48631948_48632718	4.07	COL7A1	collagen, type VII, alpha 1	260	0.83
chr8_69242814_69243988	3.87	C8orf34	chromosome 8 open reading frame 34	56	0.82
chr4_148402515_148403207	3.72	EDNRA	endothelin receptor type A	777	0.76
chr7_41740779_41741576	3.66	INHBA	inhibin, beta A	970	0.56
chr16_55513844_55514378	3.66	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	201	0.95
chr13_93879365_93880233	3.63	GPC6	glypican 6	704	0.82
chr9_129884150_129884930	3.58	ANGPTL2	angiopoietin-like 2	373	0.9
chr12_72667295_72667865	3.49	TRHDE	thyrotropin-releasing hormone degrading enzyme	317	0.85
chr6_169652381_169652976	3.38	THBS2	thrombospondin 2	432	0.89
chr22_19973614_19974692	3.30	ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	463	0.71
chr9_684288_685148	3.26	RP11-130C19.3		837	0.67
chr4_184797459_184798247	3.26	STOX2	storkhead box 2	28656	0.22
chr12_78334342_78334902	3.26	NAV3	neuron navigator 3	25434	0.27
chr20_34025363_34025770	3.21	GDF5	growth differentiation factor 5	457	0.71
chr5_63461313_63462499	3.19	RNF180	ring finger protein 180	83	0.99
chr14_23776071_23776801	3.17	BCL2L2-PABPN1	BCL2L2-PABPN1 readthrough	260	0.45
chr8_142289533_142290316	3.11	RP11-10J21.3	Uncharacterized protein	25260	0.12
chr5_131594297_131594770	3.08	PDLIM4	PDZ and LIM domain 4	1133	0.45
chr14_61123462_61124719	2.98	SIX1	SIX homeobox 1	887	0.64
chr19_676845_677141	2.97	FSTL3	follistatin-like 3 (secreted glycoprotein)	601	0.56
chr7_140016131_140016502	2.97	SLC37A3	solute carrier family 37, member 3	26973	0.14
chr11_119292436_119293234	2.95	THY1	Thy-1 cell surface antigen	437	0.74
chr5_172754207_172754714	2.93	STC2	stanniocalcin 2	596	0.75
chr8_25042452_25043634	2.91	DOCK5	dedicator of cytokinesis 5	663	0.75
chr2_159825200_159826543	2.90	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	688	0.73
chr7_143579813_143580255	2.90	FAM115A	family with sequence similarity 115, member A	36	0.98
chr6_78172796_78173983	2.90	HTR1B	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	101	0.99
chr5_141703297_141704624	2.87	SPRY4	sprouty homolog 4 (Drosophila)	213	0.88
chr4_157890038_157890662	2.86	PDGFC	platelet derived growth factor C	1705	0.41
chr2_27301899_27302732	2.82	EMILIN1	elastin microfibril interfacer 1	880	0.32
chr5_31193803_31195028	2.81	CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	558	0.85
chr15_40530958_40531718	2.81	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	46	0.96
chr2_9348603_9349207	2.78	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	2011	0.46
chr9_140500205_140501463	2.77	ARRDC1	arrestin domain containing 1	679	0.56
chr17_75316367_75316959	2.75	SEPT9	septin 9	268	0.93
chrX_110038687_110039773	2.72	CHRDL1	chordin-like 1	56	0.99
chr5_131562588_131563831	2.71	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II	138	0.96
chr6_75913619_75913933	2.70	COL12A1	collagen, type XII, alpha 1	1268	0.52
chr3_8809480_8810320	2.67	OXTR	oxytocin receptor	463	0.76
chr11_66102741_66104078	2.67	RIN1	Ras and Rab interactor 1	468	0.53
chr15_40395062_40395658	2.66	BMF	Bcl2 modifying factor	2927	0.21
chr12_59313444_59313663	2.65	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	226	0.87
chr2_180726238_180726902	2.65	ZNF385B	zinc finger protein 385B	338	0.8
chr12_53443889_53444561	2.61	TENC1	tensin like C1 domain containing phosphatase (tensin 2)	255	0.86
chr15_33011176_33011666	2.61	GREM1	gremlin 1, DAN family BMP antagonist	1216	0.49
chr5_58571069_58571855	2.61	PDE4D	phosphodiesterase 4D, cAMP-specific	483	0.9
chr6_56111778_56112295	2.60	COL21A1	collagen, type XXI, alpha 1	199	0.97
chr10_35102956_35103650	2.58	PARD3	par-3 family cell polarity regulator	946	0.5
chr17_48366854_48367409	2.58	RP11-893F2.9		1915	0.24
chr1_17867048_17867282	2.58	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like	835	0.7
chr5_150020318_150020945	2.57	SYNPO	synaptopodin	391	0.81
chr1_14924992_14926197	2.57	KAZN	kazrin, periplakin interacting protein	381	0.93
chr2_38303069_38303895	2.54	CYP1B1-AS1	CYP1B1 antisense RNA 1	156	0.5
chr9_132514889_132515259	2.54	PTGES	prostaglandin E synthase	252	0.91
chr21_38071900_38072434	2.52	SIM2	single-minded family bHLH transcription factor 2	176	0.94
chr12_118626563_118627015	2.47	TAOK3	TAO kinase 3	1538	0.42
chr9_140093629_140094566	2.47	TPRN	taperin	460	0.53
chr10_49812568_49813319	2.46	ARHGAP22	Rho GTPase activating protein 22	54	0.98
chr10_124222527_124222791	2.46	HTRA1	HtrA serine peptidase 1	1618	0.37
chr18_52626293_52626952	2.45	CCDC68	coiled-coil domain containing 68	117	0.97
chr9_139239711_139240188	2.44	GPSM1	G-protein signaling modulator 1	7560	0.12
chr1_33207592_33208218	2.44	KIAA1522	KIAA1522	419	0.8
chr19_13107353_13108160	2.44	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	1104	0.3
chr1_201915320_201915636	2.44	LMOD1	leiomodin 1 (smooth muscle)	237	0.87
chr9_130329685_130329934	2.42	FAM129B	family with sequence similarity 129, member B	1558	0.37
chr3_192126971_192127690	2.41	FGF12	fibroblast growth factor 12	492	0.87
chrX_53310382_53310778	2.40	IQSEC2	IQ motif and Sec7 domain 2	216	0.94
chr4_1035336_1035962	2.40	FGFRL1	fibroblast growth factor receptor-like 1	29410	0.11
chr11_111606115_111606547	2.39	PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	19431	0.17
chr14_75077048_75077347	2.38	LTBP2	latent transforming growth factor beta binding protein 2	1578	0.4
chr1_201436884_201437966	2.38	PHLDA3	pleckstrin homology-like domain, family A, member 3	887	0.55
chr1_99729766_99730318	2.38	LPPR4	Lipid phosphate phosphatase-related protein type 4	194	0.97
chr7_136555280_136555665	2.37	CHRM2	cholinergic receptor, muscarinic 2	1603	0.4
chr4_57276019_57276511	2.37	AC068620.1	Uncharacterized protein	417	0.79
chr19_7953693_7954073	2.36	LRRC8E	leucine rich repeat containing 8 family, member E	447	0.57
chr22_34315378_34316336	2.34	LARGE	like-glycosyltransferase	469	0.83
chr7_94537689_94537929	2.33	PPP1R9A	protein phosphatase 1, regulatory subunit 9A	218	0.96
chr19_55684291_55685412	2.33	SYT5	synaptotagmin V	1083	0.28
chr19_41195400_41196566	2.33	NUMBL	numb homolog (Drosophila)-like	44	0.96
chr2_164592268_164592669	2.32	FIGN	fidgetin	49	0.99
chr2_142887906_142888379	2.29	LRP1B	low density lipoprotein receptor-related protein 1B	432	0.87
chr18_11149170_11149978	2.28	PIEZO2	piezo-type mechanosensitive ion channel component 2	987	0.72
chr17_34611752_34612896	2.27	CCL3L1	chemokine (C-C motif) ligand 3-like 1	13395	0.14
chr1_217262846_217263329	2.26	ESRRG	estrogen-related receptor gamma	111	0.98
chr13_30002091_30002575	2.25	MTUS2	microtubule associated tumor suppressor candidate 2	431	0.89
chr3_129407054_129407730	2.24	TMCC1	transmembrane and coiled-coil domain family 1	183	0.96
chr16_2517636_2518674	2.24	RP11-715J22.2		59	0.92
chr6_137310724_137311134	2.23	RP11-204P2.3		5378	0.23
chr7_5466974_5467725	2.23	TNRC18	trinucleotide repeat containing 18	2304	0.22
chr5_178368250_178368762	2.23	ZNF454	zinc finger protein 454	282	0.89
chr20_31062740_31063476	2.22	C20orf112	chromosome 20 open reading frame 112	8166	0.18
chr19_56728415_56729241	2.22	ZSCAN5A	zinc finger and SCAN domain containing 5A	10831	0.1
chr11_86382517_86383664	2.22	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial	150	0.98
chr9_21688149_21688723	2.20	ENSG00000244230	.	10877	0.24
chr6_161649839_161650239	2.20	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4	45012	0.2
chr1_36549458_36550287	2.20	TEKT2	tektin 2 (testicular)	196	0.92
chr1_204386380_204386632	2.19	PPP1R15B	protein phosphatase 1, regulatory subunit 15B	5587	0.2
chr1_205512841_205513165	2.19	ENSG00000253097	.	22841	0.13
chr17_69971611_69971805	2.19	AC007461.1	Uncharacterized protein	64456	0.15
chrX_153601896_153602918	2.19	FLNA	filamin A, alpha	587	0.54
chr15_68871678_68872325	2.19	CORO2B	coronin, actin binding protein, 2B	428	0.9
chr5_32713757_32714054	2.19	NPR3	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)	1468	0.51
chr15_72529055_72529849	2.18	PKM	pyruvate kinase, muscle	5288	0.17
chr3_173302672_173303490	2.18	NLGN1	neuroligin 1	371	0.93
chr9_130330127_130331202	2.18	FAM129B	family with sequence similarity 129, member B	703	0.67
chr17_1665908_1666244	2.17	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	47	0.96
chr2_9396815_9397226	2.16	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	50126	0.17
chr9_85677185_85677712	2.16	RASEF	RAS and EF-hand domain containing	595	0.84
chr2_113956230_113956830	2.16	PSD4	pleckstrin and Sec7 domain containing 4	2673	0.2
chrX_105969921_105970262	2.16	RNF128	ring finger protein 128, E3 ubiquitin protein ligase	197	0.96
chr6_28442401_28443147	2.15	ZSCAN23	zinc finger and SCAN domain containing 23	31530	0.13
chr4_75718841_75720131	2.15	BTC	betacellulin	410	0.91
chr11_94134107_94135010	2.15	GPR83	G protein-coupled receptor 83	0	0.98
chr10_24757295_24757469	2.14	KIAA1217	KIAA1217	1922	0.4
chr11_120195755_120196855	2.13	TMEM136	transmembrane protein 136	289	0.9
chr9_25677269_25678110	2.13	TUSC1	tumor suppressor candidate 1	1167	0.68
chr16_65566073_65566543	2.12	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	410040	0.01
chr2_241949003_241950045	2.11	AC093585.6		637	0.62
chr2_228028292_228028853	2.11	COL4A4	collagen, type IV, alpha 4	257	0.8
chr9_116356336_116356765	2.10	RGS3	regulator of G-protein signaling 3	784	0.67
chr11_126862327_126862775	2.09	RP11-688I9.2		203	0.92
chr18_43732416_43732901	2.09	C18orf25	chromosome 18 open reading frame 25	20861	0.15
chr6_72892413_72892934	2.08	RIMS1	regulating synaptic membrane exocytosis 1	218	0.96
chr15_39871853_39872515	2.08	THBS1	thrombospondin 1	1096	0.52
chr3_134046066_134046593	2.08	AMOTL2	angiomotin like 2	44425	0.15
chr11_118492062_118492969	2.07	PHLDB1	pleckstrin homology-like domain, family B, member 1	14157	0.11
chr11_1897889_1898478	2.06	LSP1	lymphocyte-specific protein 1	476	0.66
chr9_35489468_35490886	2.05	RUSC2	RUN and SH3 domain containing 2	53	0.97
chr10_17390339_17390851	2.04	ST8SIA6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	21487	0.18
chr3_157260663_157261197	2.03	C3orf55	chromosome 3 open reading frame 55	105	0.98
chr9_40632604_40633916	2.02	SPATA31A3	SPATA31 subfamily A, member 3	67031	0.14
chr12_13351879_13352395	2.02	EMP1	epithelial membrane protein 1	2417	0.37
chr8_121137253_121137925	2.02	COL14A1	collagen, type XIV, alpha 1	237	0.96
chr19_782291_783217	2.01	PTBP1	polypyrimidine tract binding protein 1	14321	0.09
chr5_92918344_92919004	2.01	NR2F1	nuclear receptor subfamily 2, group F, member 1	369	0.84
chr16_4422135_4423224	2.01	VASN	vasorin	830	0.49
chr9_110250307_110251795	2.00	KLF4	Kruppel-like factor 4 (gut)	360	0.89
chr16_88450130_88450579	2.00	ZNF469	zinc finger protein 469	43525	0.15
chr1_214397865_214398571	2.00	SMYD2	SET and MYND domain containing 2	56358	0.16
chr11_77733968_77734525	2.00	KCTD14	potassium channel tetramerization domain containing 14	94	0.72
chr13_38444003_38444421	1.97	TRPC4	transient receptor potential cation channel, subfamily C, member 4	273	0.94
chr17_27043546_27044298	1.96	RAB34	RAB34, member RAS oncogene family	844	0.24
chr15_39873424_39874712	1.96	THBS1	thrombospondin 1	774	0.66
chr3_61546098_61546562	1.95	PTPRG	protein tyrosine phosphatase, receptor type, G	1255	0.64
chr14_85999097_85999705	1.94	FLRT2	fibronectin leucine rich transmembrane protein 2	2829	0.32
chr11_27740485_27740934	1.94	BDNF	brain-derived neurotrophic factor	585	0.82
chr7_41739624_41740047	1.94	INHBA	inhibin, beta A	372	0.87
chr19_10736478_10736985	1.94	SLC44A2	solute carrier family 44 (choline transporter), member 2	530	0.65
chr7_119913514_119913995	1.91	KCND2	potassium voltage-gated channel, Shal-related subfamily, member 2	32	0.99
chr2_75787048_75787447	1.90	EVA1A	eva-1 homolog A (C. elegans)	792	0.61
chr11_33714223_33714589	1.90	RP4-541C22.5		3841	0.2
chr3_157154723_157155399	1.89	PTX3	pentraxin 3, long	483	0.86
chr6_119069398_119069957	1.88	CEP85L	centrosomal protein 85kDa-like	38439	0.19
chr17_15166292_15166618	1.88	PMP22	peripheral myelin protein 22	549	0.68
chr14_81015419_81015845	1.88	CEP128	centrosomal protein 128kDa	31137	0.25
chr9_71939475_71940274	1.87	FAM189A2	family with sequence similarity 189, member A2	386	0.91
chr9_130860266_130860759	1.87	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	71	0.93
chr8_55294582_55295235	1.86	ENSG00000244107	.	38120	0.17
chr12_43945597_43946279	1.86	ADAMTS20	ADAM metallopeptidase with thrombospondin type 1 motif, 20	214	0.97
chr1_170633420_170634117	1.86	PRRX1	paired related homeobox 1	690	0.8
chr10_15411519_15412658	1.86	FAM171A1	family with sequence similarity 171, member A1	970	0.7
chr17_74864002_74864361	1.85	MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	357	0.88
chr12_88973452_88974158	1.85	KITLG	KIT ligand	433	0.82
chr22_18051179_18051572	1.84	SLC25A18	solute carrier family 25 (glutamate carrier), member 18	8225	0.18
chr5_98397075_98397538	1.84	ENSG00000200351	.	124855	0.06
chr2_121493751_121494304	1.84	GLI2	GLI family zinc finger 2	204	0.97
chr15_69366192_69366980	1.83	RP11-809H16.4		30681	0.17
chr2_33361191_33361342	1.83	LTBP1	latent transforming growth factor beta binding protein 1	1542	0.54
chr9_109459969_109460612	1.83	ENSG00000200131	.	18032	0.28
chr11_2847450_2848020	1.82	KCNQ1-AS1	KCNQ1 antisense RNA 1	35063	0.12
chr15_96877000_96877175	1.82	ENSG00000222651	.	597	0.47
chr4_41363336_41363659	1.82	LIMCH1	LIM and calponin homology domains 1	665	0.77
chr15_37175433_37176047	1.82	ENSG00000212511	.	30899	0.23
chr2_168148837_168149519	1.82	XIRP2	xin actin-binding repeat containing 2	105385	0.08
chr12_59311038_59311457	1.81	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	2080	0.36
chr7_80547175_80548098	1.81	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	863	0.76
chr8_86350363_86351282	1.81	CA3	carbonic anhydrase III, muscle specific	234	0.93
chr16_54970178_54971110	1.81	IRX5	iroquois homeobox 5	4660	0.36
chr10_76684287_76684702	1.81	KAT6B	K(lysine) acetyltransferase 6B	86036	0.08
chr15_90205872_90206267	1.80	PLIN1	perilipin 1	4802	0.14
chr17_13504603_13505279	1.80	HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	303	0.94
chr16_70221940_70222878	1.80	CLEC18C	C-type lectin domain family 18, member C	14349	0.1
chr11_65664383_65664636	1.80	FOSL1	FOS-like antigen 1	3381	0.1
chr11_113649028_113649338	1.80	CLDN25	claudin 25	1286	0.35
chr9_16726683_16727481	1.80	RP11-62F24.2		270	0.85
chr15_66209126_66209488	1.80	RAB11A	RAB11A, member RAS oncogene family	46956	0.13
chr21_33893367_33893849	1.80	ENSG00000252045	.	17001	0.16
chr9_35688355_35688710	1.79	TPM2	tropomyosin 2 (beta)	1368	0.2
chr6_152701966_152702349	1.79	SYNE1-AS1	SYNE1 antisense RNA 1	476	0.79
chr4_169753076_169754370	1.79	RP11-635L1.3		365	0.61
chr5_178367547_178367761	1.78	ZNF454	zinc finger protein 454	538	0.73
chr7_91195255_91195601	1.78	FZD1	frizzled family receptor 1	301645	0.01
chr22_46476561_46476775	1.78	FLJ27365	hsa-mir-4763	476	0.66

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIX_NFIB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	11.4	GO:0035385	Roundabout signaling pathway(GO:0035385)
2.7	8.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
2.7	8.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
2.5	9.8	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
2.4	2.4	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
2.4	7.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
2.2	6.6	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
2.2	8.8	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
2.1	6.2	GO:0016080	synaptic vesicle targeting(GO:0016080)
1.9	7.5	GO:0043589	skin morphogenesis(GO:0043589)
1.9	5.6	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
1.9	5.6	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
1.9	5.6	GO:0051451	myoblast migration(GO:0051451)
1.8	5.5	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
1.8	5.3	GO:0072047	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
1.7	5.2	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
1.7	5.1	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
1.7	5.1	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
1.6	1.6	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
1.6	1.6	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
1.6	3.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
1.6	6.3	GO:0070141	response to UV-A(GO:0070141)
1.6	3.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
1.5	4.5	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
1.5	7.4	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
1.5	2.9	GO:0060433	bronchus development(GO:0060433)
1.4	2.8	GO:0007500	mesodermal cell fate determination(GO:0007500)
1.4	4.1	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
1.3	5.4	GO:0010996	response to auditory stimulus(GO:0010996)
1.3	5.2	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
1.3	2.6	GO:0048807	female genitalia morphogenesis(GO:0048807)
1.3	2.5	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
1.2	8.7	GO:0033327	Leydig cell differentiation(GO:0033327)
1.2	2.5	GO:0060453	regulation of gastric acid secretion(GO:0060453)
1.2	2.4	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
1.2	2.4	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
1.2	27.5	GO:0030199	collagen fibril organization(GO:0030199)
1.2	2.4	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
1.2	2.3	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
1.2	6.9	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
1.1	2.3	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
1.1	6.7	GO:0032288	myelin assembly(GO:0032288)
1.1	1.1	GO:0060976	coronary vasculature development(GO:0060976)
1.1	1.1	GO:0001945	lymph vessel development(GO:0001945)
1.1	4.3	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.1	3.2	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
1.1	7.4	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
1.1	1.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
1.1	1.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
1.0	3.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
1.0	3.1	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
1.0	2.1	GO:0060677	ureteric bud elongation(GO:0060677)
1.0	2.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
1.0	5.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
1.0	2.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
1.0	1.0	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
1.0	4.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
1.0	2.0	GO:0060437	lung growth(GO:0060437)
1.0	2.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
1.0	11.7	GO:0042474	middle ear morphogenesis(GO:0042474)
1.0	2.9	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
1.0	3.9	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
1.0	3.8	GO:0008218	bioluminescence(GO:0008218)
1.0	1.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.9	1.9	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.9	2.8	GO:0061072	iris morphogenesis(GO:0061072)
0.9	5.7	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.9	2.8	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.9	2.8	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.9	1.8	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.9	0.9	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.9	0.9	GO:0070208	protein heterotrimerization(GO:0070208)
0.9	0.9	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.9	3.5	GO:0002551	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.9	2.6	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.9	1.7	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.9	2.6	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.8	0.8	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.8	0.8	GO:0003207	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.8	0.8	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.8	6.4	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.8	0.8	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.8	2.4	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.8	1.6	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.8	2.4	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.8	1.6	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.8	2.3	GO:0001778	plasma membrane repair(GO:0001778)
0.8	3.1	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.8	1.6	GO:0022601	menstrual cycle phase(GO:0022601)
0.8	2.3	GO:0033088	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.8	6.2	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.8	2.3	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.8	1.5	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.8	2.3	GO:0010662	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.7	4.5	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.7	0.7	GO:0022038	corpus callosum development(GO:0022038)
0.7	1.5	GO:0010193	response to ozone(GO:0010193)
0.7	1.5	GO:0060596	mammary placode formation(GO:0060596)
0.7	0.7	GO:0003079	obsolete positive regulation of natriuresis(GO:0003079)
0.7	3.6	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.7	2.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.7	2.2	GO:0010842	retina layer formation(GO:0010842)
0.7	4.3	GO:0016264	gap junction assembly(GO:0016264)
0.7	0.7	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.7	1.4	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.7	3.5	GO:0014850	response to muscle activity(GO:0014850)
0.7	0.7	GO:0042663	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.7	2.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.7	2.8	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.7	2.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.7	2.7	GO:0070091	glucagon secretion(GO:0070091)
0.7	0.7	GO:0060214	endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.7	1.3	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.7	2.0	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.7	7.3	GO:0060042	retina morphogenesis in camera-type eye(GO:0060042)
0.7	2.0	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.7	0.7	GO:0051150	regulation of smooth muscle cell differentiation(GO:0051150)
0.7	0.7	GO:0090030	regulation of steroid hormone biosynthetic process(GO:0090030)
0.7	0.7	GO:1902803	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.6	3.9	GO:0060259	regulation of feeding behavior(GO:0060259)
0.6	0.6	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.6	8.9	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.6	3.8	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.6	1.3	GO:0043615	astrocyte cell migration(GO:0043615)
0.6	1.9	GO:0021670	lateral ventricle development(GO:0021670)
0.6	0.6	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.6	4.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.6	3.0	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.6	3.6	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.6	1.2	GO:0046021	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.6	1.8	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.6	3.5	GO:0009629	response to gravity(GO:0009629)
0.6	0.6	GO:0060435	bronchiole development(GO:0060435)
0.6	1.2	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.6	0.6	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.6	1.7	GO:0060013	righting reflex(GO:0060013)
0.6	0.6	GO:0090103	cochlea morphogenesis(GO:0090103)
0.6	1.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.6	0.6	GO:0060438	trachea development(GO:0060438)
0.6	2.2	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.6	6.7	GO:0035329	hippo signaling(GO:0035329)
0.5	0.5	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.5	0.5	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.5	1.6	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.5	0.5	GO:0060346	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.5	2.7	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.5	1.1	GO:0050819	negative regulation of coagulation(GO:0050819)
0.5	1.6	GO:0071731	response to nitric oxide(GO:0071731)
0.5	1.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.5	1.1	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.5	0.5	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.5	1.6	GO:0021542	dentate gyrus development(GO:0021542)
0.5	1.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.5	3.1	GO:0002076	osteoblast development(GO:0002076)
0.5	1.6	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.5	3.6	GO:0071320	cellular response to cAMP(GO:0071320)
0.5	0.5	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.5	1.0	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.5	3.1	GO:0008228	opsonization(GO:0008228)
0.5	9.6	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.5	4.0	GO:0008038	neuron recognition(GO:0008038)
0.5	0.5	GO:0050919	negative chemotaxis(GO:0050919)
0.5	3.0	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.5	2.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.5	1.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.5	0.5	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.5	2.4	GO:0015871	choline transport(GO:0015871)
0.5	1.5	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.5	1.9	GO:0016266	O-glycan processing(GO:0016266)
0.5	0.5	GO:0001885	endothelial cell development(GO:0001885)
0.5	1.9	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.5	1.4	GO:0030091	protein repair(GO:0030091)
0.5	0.9	GO:0010171	body morphogenesis(GO:0010171)
0.5	0.5	GO:0031268	pseudopodium organization(GO:0031268)
0.5	1.8	GO:0007258	JUN phosphorylation(GO:0007258)
0.5	1.8	GO:0051014	actin filament severing(GO:0051014)
0.5	0.5	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.5	5.9	GO:0007528	neuromuscular junction development(GO:0007528)
0.5	0.9	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.5	0.9	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.5	1.4	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.5	1.8	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.5	2.3	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.4	1.3	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.4	1.3	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.4	4.4	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.4	0.4	GO:0051541	elastin metabolic process(GO:0051541)
0.4	2.2	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.4	1.3	GO:0008614	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.4	1.3	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.4	2.2	GO:0090025	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.4	1.7	GO:0045844	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.4	3.5	GO:0000052	citrulline metabolic process(GO:0000052)
0.4	0.4	GO:0055083	cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) monovalent inorganic anion homeostasis(GO:0055083)
0.4	1.3	GO:0046469	platelet activating factor metabolic process(GO:0046469)
0.4	0.9	GO:0016199	axon midline choice point recognition(GO:0016199)
0.4	2.6	GO:0043113	receptor clustering(GO:0043113)
0.4	1.3	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.4	1.7	GO:0021571	rhombomere 5 development(GO:0021571)
0.4	1.7	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.4	0.8	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.4	1.3	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.4	0.8	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.4	2.5	GO:0016540	protein autoprocessing(GO:0016540)
0.4	2.1	GO:0007350	blastoderm segmentation(GO:0007350)
0.4	3.7	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.4	0.4	GO:0010040	response to iron(II) ion(GO:0010040)
0.4	2.4	GO:0048566	embryonic digestive tract development(GO:0048566)
0.4	9.7	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.4	1.6	GO:0032836	glomerular basement membrane development(GO:0032836)
0.4	3.2	GO:0006108	malate metabolic process(GO:0006108)
0.4	0.8	GO:0030432	peristalsis(GO:0030432)
0.4	4.8	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.4	1.2	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.4	2.8	GO:0043277	apoptotic cell clearance(GO:0043277)
0.4	7.2	GO:0030574	collagen catabolic process(GO:0030574)
0.4	1.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.4	2.4	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.4	1.2	GO:0032455	nerve growth factor processing(GO:0032455)
0.4	1.6	GO:0030238	male sex determination(GO:0030238)
0.4	4.4	GO:0006893	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.4	1.2	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.4	49.4	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4	1.2	GO:0051182	coenzyme transport(GO:0051182)
0.4	0.8	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.4	1.5	GO:0002040	sprouting angiogenesis(GO:0002040)
0.4	1.5	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.4	0.4	GO:0034201	response to oleic acid(GO:0034201)
0.4	2.7	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.4	1.5	GO:0050432	catecholamine secretion(GO:0050432)
0.4	6.8	GO:0045103	intermediate filament-based process(GO:0045103)
0.4	2.3	GO:0048286	lung alveolus development(GO:0048286)
0.4	1.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.4	0.4	GO:0072070	loop of Henle development(GO:0072070)
0.4	0.7	GO:0001696	gastric acid secretion(GO:0001696)
0.4	6.0	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.4	0.4	GO:0003161	cardiac conduction system development(GO:0003161)
0.4	1.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.4	1.1	GO:0032610	interleukin-1 alpha production(GO:0032610)
0.4	0.7	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.4	2.9	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.4	1.1	GO:0008354	germ cell migration(GO:0008354)
0.4	0.7	GO:1990845	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.4	1.5	GO:0071318	cellular response to ATP(GO:0071318)
0.4	1.8	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.4	1.1	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.4	0.7	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.4	1.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.4	1.8	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.4	0.4	GO:0018126	protein hydroxylation(GO:0018126)
0.4	1.1	GO:0048539	bone marrow development(GO:0048539)
0.4	1.8	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.3	1.7	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.3	1.7	GO:0021772	olfactory bulb development(GO:0021772)
0.3	1.4	GO:0001660	fever generation(GO:0001660)
0.3	1.0	GO:0048865	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.3	0.7	GO:0014902	myotube differentiation(GO:0014902)
0.3	0.7	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.3	1.4	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.3	1.0	GO:0070230	positive regulation of lymphocyte apoptotic process(GO:0070230) positive regulation of leukocyte apoptotic process(GO:2000108)
0.3	2.3	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.3	1.3	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.3	1.0	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.3	0.3	GO:0060134	prepulse inhibition(GO:0060134)
0.3	1.0	GO:0008347	glial cell migration(GO:0008347)
0.3	4.9	GO:0007566	embryo implantation(GO:0007566)
0.3	0.3	GO:0060405	regulation of penile erection(GO:0060405)
0.3	1.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.3	1.3	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.3	0.6	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3	1.0	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.3	1.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.3	1.3	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.3	0.9	GO:0042693	muscle cell fate commitment(GO:0042693)
0.3	2.2	GO:0009404	toxin metabolic process(GO:0009404)
0.3	0.3	GO:0001710	mesodermal cell fate commitment(GO:0001710)
0.3	0.3	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.3	0.9	GO:0042482	positive regulation of odontogenesis(GO:0042482)
0.3	1.2	GO:0032376	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.3	0.3	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3	1.8	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.3	0.6	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.3	0.3	GO:0048532	anatomical structure arrangement(GO:0048532)
0.3	2.4	GO:0046718	viral entry into host cell(GO:0046718)
0.3	0.3	GO:0007132	meiotic metaphase I(GO:0007132)
0.3	0.9	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.3	0.3	GO:0007028	cytoplasm organization(GO:0007028)
0.3	2.4	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.3	1.2	GO:1901655	cellular response to ketone(GO:1901655)
0.3	0.3	GO:0010815	bradykinin catabolic process(GO:0010815)
0.3	0.3	GO:0042637	catagen(GO:0042637)
0.3	1.7	GO:0001508	action potential(GO:0001508)
0.3	3.2	GO:0015695	organic cation transport(GO:0015695)
0.3	1.1	GO:0048844	artery morphogenesis(GO:0048844)
0.3	0.6	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.3	0.6	GO:0061082	myeloid leukocyte cytokine production(GO:0061082)
0.3	0.3	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.3	3.1	GO:0007405	neuroblast proliferation(GO:0007405)
0.3	0.8	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.3	0.8	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.3	0.8	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.3	0.6	GO:0097576	vacuole fusion(GO:0097576)
0.3	1.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.3	0.3	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.3	0.8	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.3	0.3	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.3	1.4	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.3	0.5	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.3	0.3	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.3	0.8	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.3	1.3	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.3	0.5	GO:0071294	cellular response to zinc ion(GO:0071294)
0.3	1.3	GO:0007530	sex determination(GO:0007530)
0.3	2.1	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.3	0.5	GO:0035567	non-canonical Wnt signaling pathway(GO:0035567)
0.3	0.8	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.3	0.5	GO:0060033	anatomical structure regression(GO:0060033)
0.3	5.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3	0.8	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.3	0.5	GO:0035050	embryonic heart tube development(GO:0035050)
0.2	1.5	GO:0007616	long-term memory(GO:0007616)
0.2	0.7	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.2	0.2	GO:0031650	regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652)
0.2	0.7	GO:0007494	midgut development(GO:0007494)
0.2	0.5	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.2	1.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.2	0.9	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.2	0.2	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.2	0.5	GO:0050955	thermoception(GO:0050955)
0.2	0.5	GO:0021546	rhombomere development(GO:0021546)
0.2	0.5	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.2	0.2	GO:0048485	sympathetic nervous system development(GO:0048485)
0.2	0.5	GO:0033198	response to ATP(GO:0033198)
0.2	0.2	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.2	0.4	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.2	2.9	GO:0031114	regulation of microtubule depolymerization(GO:0031114)
0.2	1.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.2	2.6	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.2	0.2	GO:0044803	multi-organism membrane organization(GO:0044803)
0.2	0.4	GO:0048820	hair cycle phase(GO:0044851) hair follicle maturation(GO:0048820)
0.2	0.4	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.2	0.9	GO:0051953	negative regulation of amine transport(GO:0051953) negative regulation of amino acid transport(GO:0051956)
0.2	0.4	GO:0031112	positive regulation of microtubule polymerization or depolymerization(GO:0031112)
0.2	1.3	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.2	0.4	GO:0043266	regulation of potassium ion transport(GO:0043266)
0.2	0.2	GO:0060039	pericardium development(GO:0060039)
0.2	0.4	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.2	2.7	GO:0042402	amine catabolic process(GO:0009310) cellular biogenic amine catabolic process(GO:0042402)
0.2	0.8	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2	1.3	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2	1.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.2	0.2	GO:0003229	ventricular cardiac muscle tissue development(GO:0003229)
0.2	0.6	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.2	0.8	GO:0015889	cobalamin transport(GO:0015889)
0.2	2.5	GO:0015701	bicarbonate transport(GO:0015701)
0.2	0.4	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.2	0.4	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.2	0.6	GO:0098810	neurotransmitter reuptake(GO:0098810)
0.2	2.4	GO:0045995	regulation of embryonic development(GO:0045995)
0.2	2.4	GO:0097480	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.2	3.2	GO:2000181	negative regulation of blood vessel morphogenesis(GO:2000181)
0.2	1.0	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.2	1.4	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.2	0.4	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.2	1.8	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.2	0.2	GO:0044253	positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.2	1.4	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2	0.4	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.2	0.2	GO:0072506	cellular phosphate ion homeostasis(GO:0030643) phosphate ion homeostasis(GO:0055062) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506)
0.2	0.8	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.2	0.6	GO:0048496	maintenance of organ identity(GO:0048496)
0.2	1.1	GO:0098743	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.2	0.2	GO:0048486	parasympathetic nervous system development(GO:0048486)
0.2	0.6	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.2	2.1	GO:0048704	embryonic skeletal system morphogenesis(GO:0048704)
0.2	0.4	GO:0016246	RNA interference(GO:0016246)
0.2	1.5	GO:0007613	memory(GO:0007613)
0.2	0.9	GO:0030252	growth hormone secretion(GO:0030252)
0.2	0.7	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.2	0.9	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.2	0.6	GO:0003341	cilium movement(GO:0003341)
0.2	1.1	GO:0090280	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.2	2.0	GO:0001657	ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.2	0.4	GO:0051788	response to misfolded protein(GO:0051788)
0.2	0.2	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.2	0.4	GO:0042220	response to cocaine(GO:0042220)
0.2	0.4	GO:0060014	granulosa cell differentiation(GO:0060014)
0.2	0.4	GO:0003151	outflow tract morphogenesis(GO:0003151)
0.2	1.3	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.2	3.2	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.2	1.1	GO:0099518	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.2	0.2	GO:0002326	B cell lineage commitment(GO:0002326)
0.2	0.7	GO:0030325	adrenal gland development(GO:0030325)
0.2	0.7	GO:0032026	response to magnesium ion(GO:0032026)
0.2	1.6	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.2	0.4	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.2	2.8	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2	0.7	GO:0010107	potassium ion import(GO:0010107)
0.2	0.3	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.2	0.7	GO:0030431	sleep(GO:0030431)
0.2	0.5	GO:0090232	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.2	0.7	GO:0006590	thyroid hormone generation(GO:0006590)
0.2	1.0	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.2	1.7	GO:0050931	melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.2	0.3	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.2	2.6	GO:0051149	positive regulation of muscle cell differentiation(GO:0051149)
0.2	1.5	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.2	1.2	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.2	1.0	GO:0032400	melanosome localization(GO:0032400)
0.2	3.2	GO:0046068	cGMP metabolic process(GO:0046068)
0.2	1.0	GO:0007635	chemosensory behavior(GO:0007635)
0.2	0.8	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.2	2.5	GO:0042730	fibrinolysis(GO:0042730)
0.2	0.5	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.2	3.8	GO:0006730	one-carbon metabolic process(GO:0006730)
0.2	0.2	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.2	0.5	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.2	0.2	GO:0014904	myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.2	0.8	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.2	0.8	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.2	2.1	GO:0008272	sulfate transport(GO:0008272)
0.2	0.6	GO:0034394	protein localization to cell surface(GO:0034394)
0.2	1.0	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.2	0.2	GO:0071285	cellular response to lithium ion(GO:0071285)
0.2	0.2	GO:0070295	renal water absorption(GO:0070295)
0.2	0.8	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.2	0.3	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2	0.6	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.2	3.1	GO:0007368	determination of left/right symmetry(GO:0007368)
0.2	0.6	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.2	0.5	GO:0017121	phospholipid scrambling(GO:0017121)
0.2	0.2	GO:0046386	deoxyribose phosphate catabolic process(GO:0046386)
0.2	0.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.2	0.6	GO:0030488	tRNA methylation(GO:0030488)
0.2	2.0	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.2	0.2	GO:0043587	tongue morphogenesis(GO:0043587)
0.2	0.2	GO:0010656	negative regulation of muscle cell apoptotic process(GO:0010656)
0.1	0.3	GO:0009648	photoperiodism(GO:0009648)
0.1	0.4	GO:0000966	RNA 5'-end processing(GO:0000966)
0.1	3.4	GO:0071773	BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.1	0.4	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.1	0.4	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	0.7	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.1	0.4	GO:0009822	alkaloid catabolic process(GO:0009822)
0.1	1.0	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1	2.5	GO:0014020	primary neural tube formation(GO:0014020)
0.1	0.6	GO:0005984	disaccharide metabolic process(GO:0005984)
0.1	1.0	GO:0050807	regulation of synapse organization(GO:0050807)
0.1	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	0.4	GO:0015732	prostaglandin transport(GO:0015732)
0.1	1.0	GO:0007520	myoblast fusion(GO:0007520)
0.1	0.7	GO:0031000	response to caffeine(GO:0031000)
0.1	2.7	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.1	0.1	GO:0051955	regulation of amino acid transport(GO:0051955)
0.1	0.4	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.1	1.5	GO:0019233	sensory perception of pain(GO:0019233)
0.1	0.4	GO:0071398	cellular response to fatty acid(GO:0071398)
0.1	0.3	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.1	0.3	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1	0.3	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	1.0	GO:0051930	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1	0.1	GO:0048617	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.1	0.4	GO:0009409	response to cold(GO:0009409)
0.1	0.1	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.1	0.9	GO:0033189	response to vitamin A(GO:0033189)
0.1	0.3	GO:0099565	regulation of postsynaptic membrane potential(GO:0060078) excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.1	1.3	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1	0.8	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	0.5	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.1	0.3	GO:0055009	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.1	0.4	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.1	0.4	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.1	0.5	GO:0032206	positive regulation of telomere maintenance(GO:0032206)
0.1	0.1	GO:0001963	synaptic transmission, dopaminergic(GO:0001963)
0.1	0.3	GO:0032109	positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.1	0.1	GO:0046325	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.1	0.2	GO:0007341	penetration of zona pellucida(GO:0007341)
0.1	0.2	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.1	0.5	GO:0021766	hippocampus development(GO:0021766)
0.1	0.4	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.1	0.5	GO:0043650	glutamate biosynthetic process(GO:0006537) dicarboxylic acid biosynthetic process(GO:0043650)
0.1	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.6	GO:0006177	GMP biosynthetic process(GO:0006177)
0.1	1.5	GO:0006555	methionine metabolic process(GO:0006555)
0.1	0.7	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	0.2	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.1	0.1	GO:0006565	L-serine catabolic process(GO:0006565)
0.1	1.0	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.1	0.5	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	0.8	GO:0031529	ruffle organization(GO:0031529)
0.1	0.4	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.6	GO:0042438	melanin biosynthetic process(GO:0042438)
0.1	0.4	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.1	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	12.7	GO:0006936	muscle contraction(GO:0006936)
0.1	0.3	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.1	0.2	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.9	GO:0015074	DNA integration(GO:0015074)
0.1	0.2	GO:0007000	nucleolus organization(GO:0007000)
0.1	2.5	GO:0007588	excretion(GO:0007588)
0.1	0.5	GO:0015840	urea transport(GO:0015840)
0.1	0.2	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.1	1.5	GO:0042303	molting cycle(GO:0042303) hair cycle(GO:0042633)
0.1	1.6	GO:0051216	cartilage development(GO:0051216)
0.1	0.4	GO:0042574	retinal metabolic process(GO:0042574)
0.1	0.1	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.1	6.3	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.1	0.4	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.6	GO:0018345	protein palmitoylation(GO:0018345)
0.1	0.1	GO:0030728	ovulation(GO:0030728)
0.1	0.4	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.1	1.5	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1	0.1	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.1	0.3	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1	0.2	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1	0.1	GO:0007431	salivary gland development(GO:0007431)
0.1	0.1	GO:0048854	brain morphogenesis(GO:0048854)
0.1	2.7	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
0.1	0.7	GO:0007340	acrosome reaction(GO:0007340)
0.1	0.3	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.1	0.5	GO:0015904	tetracycline transport(GO:0015904)
0.1	0.1	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1	0.6	GO:0030865	cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.1	0.3	GO:0009649	entrainment of circadian clock(GO:0009649)
0.1	0.2	GO:0042428	serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.1	0.1	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.1	0.9	GO:0001895	retina homeostasis(GO:0001895)
0.1	0.3	GO:0060674	placenta blood vessel development(GO:0060674)
0.1	0.5	GO:0048706	embryonic skeletal system development(GO:0048706)
0.1	0.2	GO:0010269	response to selenium ion(GO:0010269)
0.1	0.1	GO:0016265	obsolete death(GO:0016265)
0.1	0.3	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	10.8	GO:0006813	potassium ion transport(GO:0006813)
0.1	0.3	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.1	0.3	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1	0.6	GO:0045980	negative regulation of nucleotide metabolic process(GO:0045980)
0.1	0.2	GO:0003032	detection of oxygen(GO:0003032)
0.1	0.1	GO:0021591	ventricular system development(GO:0021591)
0.1	0.2	GO:0010677	negative regulation of cellular carbohydrate metabolic process(GO:0010677)
0.1	0.2	GO:0002068	glandular epithelial cell development(GO:0002068)
0.1	0.4	GO:0034105	positive regulation of tissue remodeling(GO:0034105)
0.1	0.6	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	2.5	GO:0045444	fat cell differentiation(GO:0045444)
0.1	0.1	GO:0043114	regulation of vascular permeability(GO:0043114)
0.1	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.1	0.2	GO:0080111	DNA demethylation(GO:0080111)
0.1	0.5	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.1	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.1	0.7	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.1	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.1	2.6	GO:0044344	cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.1	0.1	GO:0051588	regulation of neurotransmitter secretion(GO:0046928) regulation of neurotransmitter transport(GO:0051588)
0.1	0.6	GO:1901070	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051) guanosine-containing compound biosynthetic process(GO:1901070)
0.1	0.1	GO:0010888	negative regulation of lipid storage(GO:0010888)
0.1	0.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.2	GO:0061245	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.1	0.4	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.1	0.1	GO:0085029	extracellular matrix assembly(GO:0085029)
0.1	0.3	GO:0019695	choline metabolic process(GO:0019695)
0.1	0.1	GO:0046037	GMP metabolic process(GO:0046037)
0.1	0.5	GO:0031103	axon regeneration(GO:0031103)
0.1	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.3	GO:0006477	protein sulfation(GO:0006477)
0.1	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.1	2.6	GO:0031424	keratinization(GO:0031424)
0.1	0.3	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.1	0.3	GO:0030259	lipid glycosylation(GO:0030259)
0.1	0.2	GO:0030573	bile acid catabolic process(GO:0030573)
0.1	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.1	0.1	GO:0032291	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1	4.9	GO:0001525	angiogenesis(GO:0001525)
0.1	0.2	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.1	0.1	GO:0043555	regulation of translation in response to stress(GO:0043555) regulation of translational initiation in response to stress(GO:0043558)
0.1	0.4	GO:0009650	UV protection(GO:0009650)
0.1	0.3	GO:0031670	cellular response to nutrient(GO:0031670)
0.1	0.1	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.1	0.1	GO:0060056	mammary gland involution(GO:0060056)
0.1	0.2	GO:0006857	oligopeptide transport(GO:0006857)
0.1	0.1	GO:0034694	response to prostaglandin(GO:0034694)
0.1	3.5	GO:0008544	epidermis development(GO:0008544)
0.1	0.1	GO:0061333	renal tubule morphogenesis(GO:0061333)
0.1	0.3	GO:0043030	regulation of macrophage activation(GO:0043030)
0.1	0.4	GO:0010828	positive regulation of glucose transport(GO:0010828)
0.1	0.3	GO:0021543	pallium development(GO:0021543)
0.1	0.1	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.1	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.6	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.0	GO:0014888	striated muscle adaptation(GO:0014888)
0.0	0.1	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.0	0.1	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.3	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.1	GO:0030177	positive regulation of Wnt signaling pathway(GO:0030177)
0.0	0.1	GO:0015824	proline transport(GO:0015824)
0.0	0.1	GO:0070989	oxidative demethylation(GO:0070989)
0.0	0.0	GO:0045979	positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0	0.0	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.7	GO:0016358	dendrite development(GO:0016358)
0.0	0.3	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.0	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0021794	thalamus development(GO:0021794)
0.0	0.2	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.0	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	2.2	GO:0001501	skeletal system development(GO:0001501)
0.0	0.1	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.2	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.2	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.1	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0	0.0	GO:0032099	regulation of appetite(GO:0032098) negative regulation of appetite(GO:0032099)
0.0	0.1	GO:0007019	microtubule depolymerization(GO:0007019)
0.0	0.1	GO:0090130	tissue migration(GO:0090130)
0.0	0.1	GO:0048806	genitalia development(GO:0048806)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0048167	regulation of synaptic plasticity(GO:0048167)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.3	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.1	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:0051133	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520) regulation of NK T cell activation(GO:0051133) positive regulation of NK T cell activation(GO:0051135)
0.0	0.2	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.1	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0061365	positive regulation of lipoprotein lipase activity(GO:0051006) positive regulation of triglyceride lipase activity(GO:0061365)
0.0	0.1	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.1	GO:0051043	regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0	0.1	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.0	GO:0048645	organ formation(GO:0048645)
0.0	0.0	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.3	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.2	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0042733	embryonic digit morphogenesis(GO:0042733)
0.0	0.0	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.0	GO:0001823	mesonephros development(GO:0001823)
0.0	0.0	GO:0010744	positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.5	GO:0034249	negative regulation of cellular amide metabolic process(GO:0034249)
0.0	0.0	GO:0019755	one-carbon compound transport(GO:0019755)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.0	0.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.2	GO:0001764	neuron migration(GO:0001764)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.0	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0050806	positive regulation of synaptic transmission(GO:0050806)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	11.3	GO:0030934	anchoring collagen complex(GO:0030934)
2.3	2.3	GO:0005900	oncostatin-M receptor complex(GO:0005900)
1.8	12.3	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
1.7	5.1	GO:0005588	collagen type V trimer(GO:0005588)
1.7	8.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
1.7	1.7	GO:0043260	laminin-11 complex(GO:0043260)
1.6	1.6	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
1.3	6.4	GO:0071437	invadopodium(GO:0071437)
1.2	3.5	GO:0070852	cell body fiber(GO:0070852)
1.1	3.4	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.1	9.1	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.1	1.1	GO:0031528	microvillus membrane(GO:0031528)
1.1	4.4	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
1.0	4.1	GO:0043218	compact myelin(GO:0043218)
1.0	6.1	GO:0001527	microfibril(GO:0001527)
1.0	6.7	GO:0005606	laminin-1 complex(GO:0005606)
1.0	8.6	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.9	7.3	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.9	7.0	GO:0005614	interstitial matrix(GO:0005614)
0.8	3.1	GO:0030056	hemidesmosome(GO:0030056)
0.8	0.8	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.8	3.0	GO:0030673	axolemma(GO:0030673)
0.8	0.8	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.7	3.0	GO:0005915	zonula adherens(GO:0005915)
0.7	3.0	GO:0005638	lamin filament(GO:0005638)
0.7	2.2	GO:0005899	insulin receptor complex(GO:0005899)
0.7	4.3	GO:0031512	motile primary cilium(GO:0031512)
0.6	6.5	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.6	0.6	GO:0005641	nuclear envelope lumen(GO:0005641)
0.6	3.4	GO:0010369	chromocenter(GO:0010369)
0.6	1.1	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.6	5.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.5	3.2	GO:0016012	sarcoglycan complex(GO:0016012)
0.5	1.6	GO:0043083	synaptic cleft(GO:0043083)
0.5	6.0	GO:0005581	collagen trimer(GO:0005581)
0.5	3.0	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.5	119.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.5	1.4	GO:0033270	paranode region of axon(GO:0033270)
0.5	1.9	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.5	1.4	GO:0032449	CBM complex(GO:0032449)
0.5	0.9	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.4	4.9	GO:0030315	T-tubule(GO:0030315)
0.4	1.8	GO:0033268	node of Ranvier(GO:0033268)
0.4	21.1	GO:0031012	extracellular matrix(GO:0031012)
0.4	33.7	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.4	1.3	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.4	23.3	GO:0030426	growth cone(GO:0030426)
0.4	1.2	GO:0048179	activin receptor complex(GO:0048179)
0.4	0.7	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.4	9.7	GO:0030018	Z disc(GO:0030018)
0.4	9.9	GO:0034704	calcium channel complex(GO:0034704)
0.4	5.3	GO:0009925	basal plasma membrane(GO:0009925)
0.4	0.7	GO:0005652	nuclear lamina(GO:0005652)
0.3	4.8	GO:0005913	cell-cell adherens junction(GO:0005913)
0.3	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.3	2.0	GO:0043034	costamere(GO:0043034)
0.3	8.4	GO:0042734	presynaptic membrane(GO:0042734)
0.3	25.3	GO:0005925	focal adhesion(GO:0005925)
0.3	0.6	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.3	1.1	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.3	1.8	GO:0032589	neuron projection membrane(GO:0032589)
0.3	4.5	GO:0030057	desmosome(GO:0030057)
0.3	5.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.2	0.7	GO:0031933	telomeric heterochromatin(GO:0031933)
0.2	3.2	GO:0044447	axoneme part(GO:0044447)
0.2	1.7	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2	2.5	GO:0070161	anchoring junction(GO:0070161)
0.2	0.4	GO:0043198	dendritic shaft(GO:0043198)
0.2	25.2	GO:0005911	cell-cell junction(GO:0005911)
0.2	0.7	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	0.2	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2	0.9	GO:0042589	zymogen granule membrane(GO:0042589)
0.2	4.7	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	0.4	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	6.9	GO:0034707	chloride channel complex(GO:0034707)
0.1	0.7	GO:0071546	pi-body(GO:0071546)
0.1	0.4	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	2.0	GO:0005811	lipid particle(GO:0005811)
0.1	0.4	GO:0048786	presynaptic active zone(GO:0048786)
0.1	29.3	GO:0005667	transcription factor complex(GO:0005667)
0.1	1.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	0.4	GO:0031091	platelet alpha granule(GO:0031091)
0.1	9.2	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1	0.5	GO:0031262	Ndc80 complex(GO:0031262)
0.1	1.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	0.3	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.3	GO:0032585	multivesicular body membrane(GO:0032585)
0.1	60.3	GO:0005615	extracellular space(GO:0005615)
0.1	3.7	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	0.9	GO:0001917	photoreceptor inner segment(GO:0001917)
0.1	0.2	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1	0.3	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	1.3	GO:0043197	dendritic spine(GO:0043197)
0.1	0.4	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	0.3	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	0.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.6	GO:0030686	90S preribosome(GO:0030686)
0.1	0.3	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	1.3	GO:0005859	muscle myosin complex(GO:0005859)
0.1	1.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	0.7	GO:0070652	HAUS complex(GO:0070652)
0.1	0.6	GO:0005861	troponin complex(GO:0005861)
0.1	0.8	GO:0005833	hemoglobin complex(GO:0005833)
0.1	0.5	GO:0035253	ciliary rootlet(GO:0035253)
0.1	1.5	GO:0005901	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1	1.5	GO:0031526	brush border membrane(GO:0031526)
0.1	0.3	GO:0042587	glycogen granule(GO:0042587)
0.1	1.2	GO:0008021	synaptic vesicle(GO:0008021)
0.1	0.5	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	0.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	3.7	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	8.9	GO:0005882	intermediate filament(GO:0005882)
0.1	2.7	GO:0030054	cell junction(GO:0030054)
0.1	0.8	GO:0005801	cis-Golgi network(GO:0005801)
0.0	3.7	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.6	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	2.4	GO:0001726	ruffle(GO:0001726)
0.0	1.7	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.0	GO:0030427	site of polarized growth(GO:0030427)
0.0	1.5	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.3	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.7	GO:0045177	apical part of cell(GO:0045177)
0.0	0.2	GO:0043195	terminal bouton(GO:0043195)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.7	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	1.6	GO:0098794	postsynapse(GO:0098794)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	1.5	GO:0005875	microtubule associated complex(GO:0005875)
0.0	0.3	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	2.7	GO:0036477	somatodendritic compartment(GO:0036477)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0005775	vacuolar lumen(GO:0005775)
0.0	18.8	GO:0005576	extracellular region(GO:0005576)
0.0	0.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.0	GO:0044216	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.2	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.4	GO:0030017	sarcomere(GO:0030017)
0.0	0.7	GO:0043005	neuron projection(GO:0043005)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.6	GO:0005788	endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	10.4	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
2.4	7.3	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
2.2	6.6	GO:0030215	semaphorin receptor binding(GO:0030215)
2.1	8.4	GO:0048495	Roundabout binding(GO:0048495)
1.9	5.6	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
1.7	3.5	GO:0050682	AF-2 domain binding(GO:0050682)
1.7	5.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
1.6	4.9	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
1.5	6.0	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
1.4	4.3	GO:0050501	hyaluronan synthase activity(GO:0050501)
1.4	4.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
1.4	8.4	GO:0008046	axon guidance receptor activity(GO:0008046)
1.4	8.4	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
1.3	5.3	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
1.3	3.9	GO:0070052	collagen V binding(GO:0070052)
1.3	3.9	GO:0042577	lipid phosphatase activity(GO:0042577)
1.3	5.2	GO:0045499	chemorepellent activity(GO:0045499)
1.3	3.8	GO:0003680	AT DNA binding(GO:0003680)
1.2	8.6	GO:0005110	frizzled-2 binding(GO:0005110)
1.2	11.0	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
1.2	4.8	GO:0004157	dihydropyrimidinase activity(GO:0004157)
1.2	10.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
1.1	3.4	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
1.1	5.7	GO:0070700	BMP receptor binding(GO:0070700)
1.1	2.1	GO:0019215	intermediate filament binding(GO:0019215)
1.0	3.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
1.0	8.0	GO:0017166	vinculin binding(GO:0017166)
1.0	2.9	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
1.0	2.9	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.9	3.7	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.9	2.6	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.8	3.4	GO:0004470	malic enzyme activity(GO:0004470)
0.8	11.7	GO:0005523	tropomyosin binding(GO:0005523)
0.8	2.5	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.8	2.5	GO:0002162	dystroglycan binding(GO:0002162)
0.8	7.4	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.8	4.0	GO:0005000	vasopressin receptor activity(GO:0005000)
0.8	3.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.8	16.5	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.8	2.3	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.8	2.3	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.8	2.3	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.8	3.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.8	2.3	GO:0070324	thyroid hormone binding(GO:0070324)
0.8	3.8	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.7	4.4	GO:0001968	fibronectin binding(GO:0001968)
0.7	3.6	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.7	10.0	GO:0043498	obsolete cell surface binding(GO:0043498)
0.7	5.0	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.7	2.8	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.7	2.1	GO:0005042	netrin receptor activity(GO:0005042)
0.7	2.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.7	2.0	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.7	3.4	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.7	2.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.6	43.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.6	2.6	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.6	1.9	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.6	1.9	GO:0004995	tachykinin receptor activity(GO:0004995)
0.6	1.8	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.6	13.8	GO:0017147	Wnt-protein binding(GO:0017147)
0.6	1.8	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.6	5.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.6	1.8	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.6	2.3	GO:0008179	adenylate cyclase binding(GO:0008179)
0.6	3.5	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.6	4.0	GO:0042043	neurexin family protein binding(GO:0042043)
0.6	3.4	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.6	1.7	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.6	1.7	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.5	9.9	GO:0050840	extracellular matrix binding(GO:0050840)
0.5	2.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.5	0.5	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.5	2.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.5	4.2	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.5	2.6	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.5	2.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.5	4.7	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.5	9.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.5	2.6	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.5	1.5	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.5	1.5	GO:0016151	nickel cation binding(GO:0016151)
0.5	2.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.5	2.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.5	1.5	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.5	7.9	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.5	0.5	GO:0032036	myosin heavy chain binding(GO:0032036)
0.5	4.4	GO:0005112	Notch binding(GO:0005112)
0.5	5.8	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.5	2.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.5	2.4	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.5	1.4	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.5	1.4	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.5	1.4	GO:0045545	syndecan binding(GO:0045545)
0.5	2.3	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.5	2.3	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.5	3.2	GO:0030506	ankyrin binding(GO:0030506)
0.4	1.3	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.4	2.2	GO:0005499	vitamin D binding(GO:0005499)
0.4	1.8	GO:0017154	semaphorin receptor activity(GO:0017154)
0.4	1.7	GO:0032052	bile acid binding(GO:0032052)
0.4	2.6	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.4	0.9	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.4	3.8	GO:0051378	serotonin binding(GO:0051378)
0.4	1.3	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.4	3.4	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.4	1.3	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.4	1.7	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4	2.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.4	2.7	GO:0017080	sodium channel regulator activity(GO:0017080)
0.4	2.7	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.4	1.5	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.4	2.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.4	1.5	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.4	1.5	GO:0004111	creatine kinase activity(GO:0004111)
0.4	1.5	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.4	1.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.4	1.5	GO:0005497	androgen binding(GO:0005497)
0.4	1.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.4	3.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4	1.8	GO:0030274	LIM domain binding(GO:0030274)
0.4	1.4	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3	3.8	GO:0051010	microtubule plus-end binding(GO:0051010)
0.3	1.4	GO:0001515	opioid peptide activity(GO:0001515)
0.3	4.1	GO:0005243	gap junction channel activity(GO:0005243)
0.3	3.4	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.3	1.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.3	1.7	GO:0000036	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.3	0.7	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.3	1.7	GO:0030955	potassium ion binding(GO:0030955)
0.3	1.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.3	1.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.3	1.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.3	4.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.3	36.8	GO:0008083	growth factor activity(GO:0008083)
0.3	1.6	GO:0031685	adenosine receptor binding(GO:0031685)
0.3	1.6	GO:0043274	phospholipase binding(GO:0043274)
0.3	2.5	GO:0050780	dopamine receptor binding(GO:0050780)
0.3	0.9	GO:0019798	procollagen-proline dioxygenase activity(GO:0019798)
0.3	3.8	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.3	5.0	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3	12.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.3	0.9	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3	7.1	GO:0005518	collagen binding(GO:0005518)
0.3	0.9	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.3	0.9	GO:0034056	estrogen response element binding(GO:0034056)
0.3	0.6	GO:0070411	I-SMAD binding(GO:0070411)
0.3	7.9	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.3	1.5	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3	0.9	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.3	0.9	GO:0051380	norepinephrine binding(GO:0051380)
0.3	1.2	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.3	2.9	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.3	4.1	GO:0017046	peptide hormone binding(GO:0017046)
0.3	0.9	GO:0034584	piRNA binding(GO:0034584)
0.3	1.4	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.3	1.7	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.3	3.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.3	0.8	GO:0035198	miRNA binding(GO:0035198)
0.3	3.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.3	1.4	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.3	3.6	GO:0031490	chromatin DNA binding(GO:0031490)
0.3	0.8	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.3	0.3	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.3	0.8	GO:0030507	spectrin binding(GO:0030507)
0.3	1.3	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.3	0.8	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.3	0.8	GO:0005534	galactose binding(GO:0005534)
0.3	1.0	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.3	0.8	GO:0046923	ER retention sequence binding(GO:0046923)
0.3	4.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.3	16.9	GO:0008201	heparin binding(GO:0008201)
0.3	2.0	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.2	2.7	GO:0030553	cGMP binding(GO:0030553)
0.2	0.5	GO:0004630	phospholipase D activity(GO:0004630)
0.2	3.1	GO:0045296	cadherin binding(GO:0045296)
0.2	0.2	GO:0030172	troponin C binding(GO:0030172)
0.2	1.2	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.2	2.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.2	2.4	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2	2.1	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.2	0.9	GO:0003696	satellite DNA binding(GO:0003696)
0.2	0.9	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2	64.9	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.2	1.4	GO:0034235	GPI anchor binding(GO:0034235)
0.2	3.0	GO:0005003	ephrin receptor activity(GO:0005003)
0.2	1.8	GO:0070628	proteasome binding(GO:0070628)
0.2	22.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.2	0.2	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.2	0.7	GO:0050321	tau-protein kinase activity(GO:0050321)
0.2	0.7	GO:0016805	dipeptidase activity(GO:0016805)
0.2	1.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.2	3.7	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2	2.2	GO:0051183	vitamin transporter activity(GO:0051183)
0.2	0.9	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.2	9.6	GO:0051015	actin filament binding(GO:0051015)
0.2	0.8	GO:0031996	thioesterase binding(GO:0031996)
0.2	3.1	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.2	0.8	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2	0.4	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.2	1.0	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.2	2.0	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.2	6.0	GO:0008013	beta-catenin binding(GO:0008013)
0.2	0.6	GO:0004461	lactose synthase activity(GO:0004461)
0.2	0.6	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.2	3.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.2	0.8	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2	3.6	GO:0016917	GABA receptor activity(GO:0016917)
0.2	1.4	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.2	0.6	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.2	1.6	GO:0015245	fatty acid transporter activity(GO:0015245)
0.2	0.6	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2	0.6	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.2	1.5	GO:0030332	cyclin binding(GO:0030332)
0.2	0.9	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.2	2.1	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.2	0.5	GO:0008502	melatonin receptor activity(GO:0008502)
0.2	2.7	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2	2.0	GO:0019894	kinesin binding(GO:0019894)
0.2	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.2	0.5	GO:0032794	GTPase activating protein binding(GO:0032794)
0.2	0.3	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.2	0.5	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2	0.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.2	0.9	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.2	0.2	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2	1.4	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.2	0.5	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.2	0.6	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2	3.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.2	3.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1	0.4	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1	0.7	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1	0.6	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	0.3	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
0.1	1.5	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.1	0.7	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1	2.7	GO:0005158	insulin receptor binding(GO:0005158)
0.1	0.3	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	0.9	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	1.7	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.1	0.6	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.8	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.4	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.1	0.6	GO:0017081	chloride channel regulator activity(GO:0017081)
0.1	0.1	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.4	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.9	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.1	0.4	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.1	0.4	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.9	GO:0008242	omega peptidase activity(GO:0008242)
0.1	0.6	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	9.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.3	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.2	GO:0004938	adrenergic receptor activity(GO:0004935) alpha2-adrenergic receptor activity(GO:0004938)
0.1	1.0	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.4	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.1	0.6	GO:0015368	calcium:cation antiporter activity(GO:0015368)
0.1	0.4	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.6	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	0.4	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	1.8	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.1	0.5	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.6	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	2.1	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	0.3	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.1	2.0	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	0.3	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	1.0	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.1	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1	0.4	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1	0.3	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1	0.1	GO:0046848	hydroxyapatite binding(GO:0046848)
0.1	0.7	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.6	GO:0008493	tetracycline transporter activity(GO:0008493)
0.1	0.5	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.6	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.5	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.8	GO:0005132	type I interferon receptor binding(GO:0005132)
0.1	0.7	GO:0000339	RNA cap binding(GO:0000339)
0.1	0.3	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1	0.4	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.1	0.3	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	0.3	GO:0004064	arylesterase activity(GO:0004064)
0.1	0.7	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	6.2	GO:0008237	metallopeptidase activity(GO:0008237)
0.1	0.5	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.2	GO:0032190	acrosin binding(GO:0032190)
0.1	0.2	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	0.5	GO:0050811	GABA receptor binding(GO:0050811)
0.1	5.6	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.1	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.5	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	1.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	6.2	GO:0005179	hormone activity(GO:0005179)
0.1	0.6	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.1	0.2	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	0.6	GO:0019841	retinol binding(GO:0019841)
0.1	0.1	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1	0.3	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.1	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.4	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.3	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.1	0.3	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.3	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.1	0.5	GO:0008158	hedgehog receptor activity(GO:0008158)
0.1	0.4	GO:0000146	microfilament motor activity(GO:0000146)
0.1	0.3	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1	0.2	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1	0.7	GO:0005542	folic acid binding(GO:0005542)
0.1	0.6	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	1.0	GO:0008527	taste receptor activity(GO:0008527)
0.1	0.2	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1	0.6	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	30.0	GO:0005509	calcium ion binding(GO:0005509)
0.1	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.1	0.3	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.1	1.0	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.1	0.7	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	0.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1	0.3	GO:0045502	dynein binding(GO:0045502)
0.0	3.3	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0	1.0	GO:0070330	aromatase activity(GO:0070330)
0.0	0.8	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.2	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.4	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.2	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.4	GO:0008430	selenium binding(GO:0008430)
0.0	0.3	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.5	GO:0005310	dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0008443	6-phosphofructo-2-kinase activity(GO:0003873) phosphofructokinase activity(GO:0008443)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.0	GO:0022835	transmitter-gated ion channel activity(GO:0022824) transmitter-gated channel activity(GO:0022835)
0.0	5.1	GO:0008236	serine-type peptidase activity(GO:0008236)
0.0	0.1	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.2	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.0	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0008066	glutamate receptor activity(GO:0008066)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.0	GO:0031420	alkali metal ion binding(GO:0031420)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.4	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.3	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.2	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.2	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.0	GO:0005415	nucleoside:sodium symporter activity(GO:0005415)
0.0	0.2	GO:0048038	quinone binding(GO:0048038)
0.0	0.3	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	1.2	GO:0005254	chloride channel activity(GO:0005254)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	1.2	GO:0004497	monooxygenase activity(GO:0004497)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.4	GO:0030971	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.5	GO:0070405	ammonium ion binding(GO:0070405)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.5	GO:0032934	sterol binding(GO:0032934)
0.0	0.2	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0080031	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.0	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.6	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0	0.0	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.1	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.3	GO:0008483	transaminase activity(GO:0008483)
0.0	0.3	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.1	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.3	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.0	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	13.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
1.3	1.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
1.1	48.4	NABA COLLAGENS	Genes encoding collagen proteins
0.9	0.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.8	12.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.7	34.0	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.6	17.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.5	4.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.5	6.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.5	18.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.4	0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.4	71.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.4	10.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.4	0.8	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.4	11.9	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.4	7.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.4	7.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.3	4.5	PID ALK1 PATHWAY	ALK1 signaling events
0.3	6.6	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.3	3.7	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3	2.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.3	0.6	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.3	1.8	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.3	5.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.3	1.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.3	10.7	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.3	1.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	9.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.2	5.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.2	4.5	PID EPHB FWD PATHWAY	EPHB forward signaling
0.2	3.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.2	53.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	2.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.2	3.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	4.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2	9.0	PID BMP PATHWAY	BMP receptor signaling
0.2	1.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.2	3.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.2	1.7	ST G ALPHA S PATHWAY	G alpha s Pathway
0.2	5.8	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.2	1.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	4.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.2	1.4	PID FGF PATHWAY	FGF signaling pathway
0.1	4.1	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	2.6	PID AURORA A PATHWAY	Aurora A signaling
0.1	20.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	1.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	0.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	32.6	NABA MATRISOME	Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.1	1.9	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	1.2	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	0.9	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	0.1	PID MYC PATHWAY	C-MYC pathway
0.1	0.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	1.0	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.5	PID CDC42 PATHWAY	CDC42 signaling events
0.0	1.0	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.6	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	19.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
1.3	1.3	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
1.1	59.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
1.0	2.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.8	22.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.8	18.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.8	12.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.8	10.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.7	16.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.7	17.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.6	22.0	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.6	1.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.5	5.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.5	0.5	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.5	9.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.5	10.0	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.5	4.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.5	8.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.5	1.9	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.5	6.6	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.5	10.4	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.5	0.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.4	3.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.4	6.8	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.4	2.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.4	2.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4	3.8	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.4	2.9	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.3	4.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.3	0.7	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.3	2.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3	3.7	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.3	4.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3	3.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.3	3.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.3	2.9	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3	3.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.3	6.1	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.3	0.3	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.3	3.7	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3	3.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.3	1.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.3	3.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.3	2.5	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.2	1.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.2	2.9	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2	1.9	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.2	2.8	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.2	1.6	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.2	2.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	4.8	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.2	6.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	2.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.2	2.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.2	0.2	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.2	1.7	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.2	3.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.2	1.0	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.2	1.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.2	3.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.2	1.7	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	2.0	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.2	1.5	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.1	6.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	3.9	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	1.9	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	0.7	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	1.6	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.1	3.1	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.1	1.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	0.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	9.5	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	2.3	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.1	2.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	2.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	1.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	1.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	0.2	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.1	1.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	1.0	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.1	0.7	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	6.0	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	0.8	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	3.4	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	0.4	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.1	1.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	0.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	0.7	REACTOME GLYCOSAMINOGLYCAN METABOLISM	Genes involved in Glycosaminoglycan metabolism
0.1	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	1.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	1.2	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.6	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	1.1	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	2.3	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.4	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.7	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.3	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha

Results for NFIX_NFIB

Z-value: 7.51

Motif logo

Transcription factors associated with NFIX_NFIB

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the NFIX_NFIB motif across conditions

Conditions sorted by the z-value of the NFIX_NFIB motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIX_NFIB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: