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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for NFKB1

Z-value: 1.34

Motif logo

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Transcription factors associated with NFKB1

Gene Symbol Gene ID Gene Info
NFKB1
ENSG00000109320.7 nuclear factor kappa B subunit 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_103425319_103425470NFKB18620.6141790.962.6e-05Click!
chr4_103425152_103425303NFKB16950.6929900.963.2e-05Click!
chr4_103541720_103541875NFKB1427760.157378-0.924.0e-04Click!
chr4_103534410_103534561NFKB1354640.1742110.901.1e-03Click!
chr4_103449015_103449166NFKB1245580.1766480.862.7e-03Click!

Activity of the NFKB1 motif across conditions

Conditions sorted by the z-value of the NFKB1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_134143747_134144006 1.05 FAM78A
 family with sequence similarity 78, member A
 2004
 0.31
chr15_45409056_45409207 0.87 DUOX2
 dual oxidase 2
 2589
 0.14
chr4_100738641_100738957 0.86 DAPP1
 dual adaptor of phosphotyrosine and 3-phosphoinositides
 796
 0.72
chr19_49839028_49839359 0.85 CD37
 CD37 molecule
 472
 0.63
chr7_26333293_26333815 0.79 SNX10
 sorting nexin 10
 880
 0.67
chr8_126964027_126964178 0.71 ENSG00000206695
 .
 50907
 0.19
chr7_30766706_30766866 0.62 INMT
 indolethylamine N-methyltransferase
 24965
 0.16
chr2_113932280_113932569 0.62 AC016683.5
490
 0.59
chr19_38908265_38908571 0.62 RASGRP4
 RAS guanyl releasing protein 4
 8384
 0.09
chr1_9688741_9688898 0.62 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 22971
 0.15
chr2_219744680_219744914 0.60 WNT10A
 wingless-type MMTV integration site family, member 10A
 288
 0.85
chr5_153582547_153582698 0.60 GALNT10
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
 12288
 0.25
chr1_31227757_31227908 0.60 LAPTM5
 lysosomal protein transmembrane 5
 2835
 0.23
chr20_43597999_43598419 0.59 STK4
 serine/threonine kinase 4
 3042
 0.19
chr19_1074414_1074782 0.57 HMHA1
 histocompatibility (minor) HA-1
 2844
 0.13
chr10_121298283_121299012 0.57 RGS10
 regulator of G-protein signaling 10
 2602
 0.34
chr22_37545294_37545803 0.54 IL2RB
 interleukin 2 receptor, beta
 482
 0.7
chr9_134604865_134605016 0.54 ENSG00000240853
 .
 4086
 0.24
chr7_37487305_37488000 0.54 ELMO1
 engulfment and cell motility 1
 901
 0.61
chrX_70837784_70838022 0.53 CXCR3
 chemokine (C-X-C motif) receptor 3
 457
 0.81
chr22_50232554_50232757 0.53 BRD1
 bromodomain containing 1
 11495
 0.18
chr15_41775317_41775468 0.52 RTF1
 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
 8525
 0.13
chr17_80279192_80279518 0.52 CD7
 CD7 molecule
 3877
 0.13
chr20_4795121_4795462 0.51 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
 478
 0.82
chr19_54672117_54672268 0.50 TMC4
 transmembrane channel-like 4
 4255
 0.08
chr2_219259559_219259710 0.50 CTDSP1
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
 3427
 0.11
chr12_111115977_111116128 0.50 HVCN1
 hydrogen voltage-gated channel 1
 10462
 0.16
chr22_18923115_18923266 0.50 PRODH
 proline dehydrogenase (oxidase) 1
 465
 0.79
chr22_30475055_30475206 0.50 HORMAD2
 HORMA domain containing 2
 1033
 0.38
chr6_132113440_132113591 0.50 ENSG00000266807
 .
 203
 0.94
chr17_38024211_38024362 0.50 ZPBP2
 zona pellucida binding protein 2
 131
 0.95
chr14_61788916_61789580 0.49 PRKCH
 protein kinase C, eta
 134
 0.7
chr1_8000859_8001010 0.49 TNFRSF9
 tumor necrosis factor receptor superfamily, member 9
 8
 0.98
chr1_92269793_92270018 0.49 ENSG00000239794
 .
 25726
 0.22
chr17_75103749_75103900 0.48 ENSG00000234912
 .
 18435
 0.18
chr3_71833354_71833608 0.48 PROK2
 prokineticin 2
 731
 0.68
chr5_176857238_176857389 0.47 GRK6
 G protein-coupled receptor kinase 6
 3458
 0.12
chr13_71865361_71865710 0.47 DACH1
 dachshund homolog 1 (Drosophila)
 575372
 0.0
chr9_123688442_123688941 0.46 TRAF1
 TNF receptor-associated factor 1
 2356
 0.33
chr17_72755238_72755446 0.46 SLC9A3R1
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
 2800
 0.14
chr16_29822482_29822845 0.46 PRRT2
 proline-rich transmembrane protein 2
 514
 0.38
chr16_29678066_29678245 0.45 QPRT
 quinolinate phosphoribosyltransferase
 3555
 0.15
chr20_35463892_35464165 0.45 SOGA1
 suppressor of glucose, autophagy associated 1
 19344
 0.15
chr1_26872928_26873171 0.45 RPS6KA1
 ribosomal protein S6 kinase, 90kDa, polypeptide 1
 706
 0.6
chr16_78776576_78776802 0.45 RP11-319G9.3
154373
 0.04
chr6_75458992_75459143 0.44 ENSG00000264884
 .
 29508
 0.26
chr2_25585755_25585961 0.44 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
 20399
 0.2
chrX_128915626_128915992 0.43 SASH3
 SAM and SH3 domain containing 3
 1849
 0.35
chr6_138028959_138029110 0.43 ENSG00000216097
 .
 9051
 0.27
chr11_721054_721205 0.43 AP006621.9
5918
 0.08
chr20_62368373_62368670 0.42 LIME1
 Lck interacting transmembrane adaptor 1
 116
 0.89
chr12_7065402_7065553 0.42 PTPN6
 protein tyrosine phosphatase, non-receptor type 6
 4939
 0.06
chr5_134879321_134879990 0.42 NEUROG1
 neurogenin 1
 8016
 0.18
chr7_74179826_74180081 0.42 NCF1
 neutrophil cytosolic factor 1
 8356
 0.2
chr6_32159695_32160229 0.42 GPSM3
 G-protein signaling modulator 3
 683
 0.42
chr7_72626118_72626352 0.42 NCF1B
 neutrophil cytosolic factor 1B pseudogene
 8376
 0.18
chr16_17624024_17624268 0.41 XYLT1
 xylosyltransferase I
 59408
 0.17
chr19_2083107_2083981 0.41 MOB3A
 MOB kinase activator 3A
 1847
 0.21
chr1_895544_895695 0.41 KLHL17
 kelch-like family member 17
 348
 0.67
chr7_74596048_74596381 0.41 GTF2IRD2B
 GTF2I repeat domain containing 2B
 39310
 0.17
chrX_30594869_30596024 0.41 CXorf21
 chromosome X open reading frame 21
 515
 0.84
chr6_106969857_106970345 0.40 AIM1
 absent in melanoma 1
 10371
 0.2
chr2_10548224_10548465 0.40 HPCAL1
 hippocalcin-like 1
 11803
 0.19
chr1_154300198_154300512 0.40 ATP8B2
 ATPase, aminophospholipid transporter, class I, type 8B, member 2
 79
 0.94
chr1_166459489_166459697 0.39 FAM78B
 family with sequence similarity 78, member B
 323387
 0.01
chr1_2455307_2455458 0.39 PANK4
 pantothenate kinase 4
 2653
 0.14
chr17_37932472_37932886 0.39 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 1799
 0.27
chr1_6526104_6526255 0.39 TNFRSF25
 tumor necrosis factor receptor superfamily, member 25
 12
 0.96
chr19_40447803_40447954 0.39 FCGBP
 Fc fragment of IgG binding protein
 7345
 0.17
chr7_2445424_2445909 0.39 CHST12
 carbohydrate (chondroitin 4) sulfotransferase 12
 1932
 0.35
chr5_140997925_140998467 0.38 AC008781.7
215
 0.56
chr17_264289_264440 0.38 AC108004.3
550
 0.69
chr17_66286056_66286766 0.38 SLC16A6
 solute carrier family 16, member 6
 846
 0.47
chr17_43297952_43298150 0.38 CTD-2020K17.1
259
 0.8
chrX_48793999_48794379 0.38 PIM2
 pim-2 oncogene
 17888
 0.08
chr11_69065156_69065401 0.38 MYEOV
 myeloma overexpressed
 3653
 0.34
chr20_52205540_52206428 0.37 ZNF217
 zinc finger protein 217
 4394
 0.22
chr2_10860609_10860760 0.36 ATP6V1C2
 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
 1091
 0.47
chr12_122228420_122228575 0.36 RHOF
 ras homolog family member F (in filopodia)
 2769
 0.23
chr14_22994691_22994955 0.36 TRAJ15
 T cell receptor alpha joining 15
 3757
 0.14
chr19_5805561_5805712 0.36 DUS3L
 dihydrouridine synthase 3-like (S. cerevisiae)
 14387
 0.08
chr15_81586254_81586487 0.35 IL16
 interleukin 16
 2884
 0.28
chr10_124136372_124136523 0.35 PLEKHA1
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
 2097
 0.31
chr10_135089818_135090113 0.35 ADAM8
 ADAM metallopeptidase domain 8
 389
 0.74
chr14_94425760_94425911 0.35 ASB2
 ankyrin repeat and SOCS box containing 2
 2068
 0.26
chr5_125937096_125937334 0.34 PHAX
 phosphorylated adaptor for RNA export
 1255
 0.44
chr1_207495095_207495855 0.34 CD55
 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
 339
 0.92
chr19_46283149_46283300 0.34 DMPK
 dystrophia myotonica-protein kinase
 575
 0.52
chr9_139927070_139927409 0.34 FUT7
 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
 223
 0.78
chr6_11852612_11852763 0.34 ADTRP
 androgen-dependent TFPI-regulating protein
 45408
 0.18
chr8_59717634_59717850 0.34 ENSG00000201231
 .
 9369
 0.29
chr22_37639776_37640249 0.33 RAC2
 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
 276
 0.88
chr16_4256693_4256974 0.33 SRL
 sarcalumenin
 32911
 0.15
chr1_154474731_154474966 0.33 TDRD10
 tudor domain containing 10
 153
 0.63
chr19_48824738_48825145 0.33 EMP3
 epithelial membrane protein 3
 175
 0.9
chr10_111971435_111971586 0.33 MXI1
 MAX interactor 1, dimerization protein
 1521
 0.41
chr6_18155802_18156067 0.33 KDM1B
 lysine (K)-specific demethylase 1B
 251
 0.78
chr3_112215334_112215665 0.33 BTLA
 B and T lymphocyte associated
 2706
 0.33
chr12_12870481_12870701 0.32 CDKN1B
 cyclin-dependent kinase inhibitor 1B (p27, Kip1)
 165
 0.93
chr10_99609976_99610583 0.32 GOLGA7B
 golgin A7 family, member B
 283
 0.91
chr15_31638589_31638828 0.32 KLF13
 Kruppel-like factor 13
 6572
 0.32
chr10_73869476_73869627 0.32 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 20761
 0.19
chr7_44790648_44790799 0.32 ZMIZ2
 zinc finger, MIZ-type containing 2
 2193
 0.28
chr20_48419063_48419214 0.31 ENSG00000252540
 .
 7790
 0.16
chr17_74268969_74269120 0.31 UBALD2
 UBA-like domain containing 2
 7260
 0.13
chr1_208417858_208418217 0.31 PLXNA2
 plexin A2
 372
 0.93
chr2_240219542_240220118 0.31 ENSG00000265215
 .
 7327
 0.19
chr3_142800787_142800938 0.31 CHST2
 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
 37311
 0.15
chr18_10451924_10452075 0.31 APCDD1
 adenomatosis polyposis coli down-regulated 1
 2626
 0.36
chr9_38042423_38042574 0.30 SHB
 Src homology 2 domain containing adaptor protein B
 26710
 0.21
chr19_1469984_1470717 0.30 ENSG00000267317
 .
 7586
 0.07
chr1_16488827_16488993 0.30 RP11-276H7.3
3149
 0.15
chr7_134855680_134855894 0.30 C7orf49
 chromosome 7 open reading frame 49
 240
 0.89
chr1_226922169_226922483 0.30 ITPKB
 inositol-trisphosphate 3-kinase B
 2833
 0.32
chr15_79236726_79237037 0.30 CTSH
 cathepsin H
 552
 0.76
chr3_185647070_185647439 0.30 TRA2B
 transformer 2 beta homolog (Drosophila)
 5573
 0.22
chr22_31686910_31687128 0.30 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
 1362
 0.25
chr17_73840046_73840332 0.30 UNC13D
 unc-13 homolog D (C. elegans)
 226
 0.84
chr9_123690633_123691433 0.30 TRAF1
 TNF receptor-associated factor 1
 14
 0.98
chr19_1068869_1069054 0.29 HMHA1
 histocompatibility (minor) HA-1
 1464
 0.22
chr3_119187850_119188681 0.29 POGLUT1
 protein O-glucosyltransferase 1
 455
 0.54
chr10_129861236_129861473 0.29 PTPRE
 protein tyrosine phosphatase, receptor type, E
 15520
 0.26
chr12_49391673_49391824 0.29 RP11-386G11.5
402
 0.59
chr7_128578118_128579002 0.29 IRF5
 interferon regulatory factor 5
 289
 0.89
chr4_90228457_90229530 0.29 GPRIN3
 GPRIN family member 3
 168
 0.97
chrX_53741093_53741244 0.29 HUWE1
 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
 27495
 0.23
chr1_226899370_226899800 0.29 ITPKB
 inositol-trisphosphate 3-kinase B
 25574
 0.18
chr1_247242173_247242440 0.29 ZNF670
 zinc finger protein 670
 249
 0.91
chr17_41738065_41738244 0.29 MEOX1
 mesenchyme homeobox 1
 777
 0.64
chr2_74153401_74153920 0.29 DGUOK
 deoxyguanosine kinase
 293
 0.89
chr22_39708334_39708626 0.29 ENSG00000209480
 .
 1436
 0.25
chr17_47572677_47573321 0.28 NGFR
 nerve growth factor receptor
 344
 0.86
chr16_68321366_68321603 0.28 ENSG00000252026
 .
 3263
 0.1
chr1_6520532_6520815 0.28 TNFRSF25
 tumor necrosis factor receptor superfamily, member 25
 5017
 0.12
chr1_31229648_31230364 0.28 LAPTM5
 lysosomal protein transmembrane 5
 661
 0.67
chr19_11533070_11533503 0.28 RGL3
 ral guanine nucleotide dissociation stimulator-like 3
 3268
 0.1
chr19_50400390_50400724 0.28 IL4I1
 interleukin 4 induced 1
 345
 0.67
chr2_219745053_219745526 0.28 WNT10A
 wingless-type MMTV integration site family, member 10A
 204
 0.9
chr6_30798000_30798388 0.28 ENSG00000202241
 .
 33833
 0.07
chr11_69457554_69457705 0.28 CCND1
 cyclin D1
 1655
 0.41
chr16_28996496_28996848 0.28 LAT
 linker for activation of T cells
 11
 0.94
chr5_150465316_150465727 0.28 TNIP1
 TNFAIP3 interacting protein 1
 1198
 0.49
chr1_55681102_55681610 0.28 USP24
 ubiquitin specific peptidase 24
 570
 0.79
chr16_80690406_80690960 0.28 ENSG00000265341
 .
 8777
 0.18
chr16_3210084_3210235 0.28 CASP16
 caspase 16, apoptosis-related cysteine peptidase (putative)
 15915
 0.08
chr1_16292676_16293171 0.28 ZBTB17
 zinc finger and BTB domain containing 17
 9651
 0.13
chr3_9690857_9691008 0.28 MTMR14
 myotubularin related protein 14
 185
 0.94
chr7_5183512_5184010 0.27 ZNF890P
 zinc finger protein 890, pseudogene
 16335
 0.17
chr9_139424881_139425156 0.27 ENSG00000263403
 .
 10940
 0.09
chr11_118016214_118016693 0.27 SCN4B
 sodium channel, voltage-gated, type IV, beta subunit
 7082
 0.15
chr22_37703418_37703750 0.27 CYTH4
 cytohesin 4
 2425
 0.26
chr20_48329922_48330172 0.27 B4GALT5
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
 368
 0.87
chr8_28205045_28205788 0.27 ZNF395
 zinc finger protein 395
 3667
 0.19
chr19_661226_661492 0.27 RNF126
 ring finger protein 126
 43
 0.95
chrX_48794595_48794842 0.27 PIM2
 pim-2 oncogene
 18417
 0.08
chr22_44392181_44392448 0.27 PARVB
 parvin, beta
 2777
 0.29
chr17_61778727_61779133 0.27 LIMD2
 LIM domain containing 2
 398
 0.8
chr19_46145825_46145976 0.26 EML2
 echinoderm microtubule associated protein like 2
 80
 0.9
chr8_21769341_21769492 0.26 DOK2
 docking protein 2, 56kDa
 1758
 0.36
chr15_45003095_45003549 0.26 B2M
 beta-2-microglobulin
 353
 0.83
chr10_15211128_15211858 0.26 NMT2
 N-myristoyltransferase 2
 801
 0.67
chr20_4788995_4789146 0.26 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
 6699
 0.21
chr19_49362125_49362344 0.26 PLEKHA4
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
 397
 0.71
chr14_103285531_103285798 0.26 TRAF3
 TNF receptor-associated factor 3
 11027
 0.17
chr8_134069456_134069607 0.26 SLA
 Src-like-adaptor
 3072
 0.32
chr2_95691472_95692130 0.25 MAL
 mal, T-cell differentiation protein
 263
 0.76
chr15_41234314_41234975 0.25 CHAC1
 ChaC, cation transport regulator homolog 1 (E. coli)
 10516
 0.12
chr19_18061359_18061510 0.25 KCNN1
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
 668
 0.61
chr1_16490997_16491148 0.25 RP11-276H7.3
5311
 0.12
chr1_27113866_27114017 0.25 PIGV
 phosphatidylinositol glycan anchor biosynthesis, class V
 22
 0.96
chr13_25254086_25254684 0.25 ATP12A
 ATPase, H+/K+ transporting, nongastric, alpha polypeptide
 164
 0.96
chr6_43483991_43484670 0.25 YIPF3
 Yip1 domain family, member 3
 22
 0.85
chr15_86127194_86127729 0.25 RP11-815J21.2
4052
 0.21
chr2_26569363_26569689 0.25 GPR113
 G protein-coupled receptor 113
 85
 0.88
chr1_32739822_32739973 0.25 LCK
 lymphocyte-specific protein tyrosine kinase
 34
 0.95
chr17_38020283_38020945 0.25 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 173
 0.93
chr10_105437541_105438126 0.25 SH3PXD2A
 SH3 and PX domains 2A
 89
 0.97
chr7_158938159_158938310 0.25 VIPR2
 vasoactive intestinal peptide receptor 2
 585
 0.86
chr19_3786043_3786321 0.25 MATK
 megakaryocyte-associated tyrosine kinase
 98
 0.94
chr13_109148449_109148673 0.25 MYO16
 myosin XVI
 99939
 0.08
chr7_44679217_44679482 0.25 OGDH
 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
 15288
 0.18
chr17_56421831_56421982 0.24 SUPT4H1
 suppressor of Ty 4 homolog 1 (S. cerevisiae)
 7116
 0.11
chr5_42924026_42924397 0.24 SEPP1
 selenoprotein P, plasma, 1
 36717
 0.17
chr18_13136915_13137798 0.24 RP11-794M8.1
78968
 0.08
chr10_114135452_114136486 0.24 ACSL5
 acyl-CoA synthetase long-chain family member 5
 12
 0.98
chr10_65021596_65021747 0.24 JMJD1C
 jumonji domain containing 1C
 7155
 0.29
chr10_75634514_75635168 0.24 CAMK2G
 calcium/calmodulin-dependent protein kinase II gamma
 498
 0.7
chr14_21571987_21572281 0.24 ZNF219
 zinc finger protein 219
 396
 0.72
chr19_39106930_39107372 0.24 MAP4K1
 mitogen-activated protein kinase kinase kinase kinase 1
 1413
 0.27
chr9_125667781_125668094 0.24 RC3H2
 ring finger and CCCH-type domains 2
 317
 0.82
chr14_91879963_91880132 0.24 CCDC88C
 coiled-coil domain containing 88C
 3643
 0.29
chr1_154979027_154979178 0.24 ZBTB7B
 zinc finger and BTB domain containing 7B
 3807
 0.09
chr12_105063987_105064138 0.24 ENSG00000264295
 .
 78651
 0.1
chr14_52313408_52314007 0.24 GNG2
 guanine nucleotide binding protein (G protein), gamma 2
 137
 0.97
chr22_50967987_50968138 0.24 TYMP
 thymidine phosphorylase
 357
 0.66
chr6_32158116_32158500 0.24 PBX2
 pre-B-cell leukemia homeobox 2
 345
 0.7
chr19_8274217_8274814 0.24 CERS4
 ceramide synthase 4
 3
 0.97
chr16_57318716_57318953 0.24 PLLP
 plasmolipin
 235
 0.9
chr17_55338552_55338703 0.24 MSI2
 musashi RNA-binding protein 2
 4248
 0.31
chr2_25537366_25537517 0.24 ENSG00000221445
 .
 14149
 0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0006562 proline catabolic process(GO:0006562)
0.1 0.8 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.3 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.2 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.5 GO:0051642 centrosome localization(GO:0051642)
0.1 0.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 0.3 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.2 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.2 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.2 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.1 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.1 0.1 GO:0072110 glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124)
0.1 0.1 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) regulation of apoptotic process involved in morphogenesis(GO:1902337) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) regulation of apoptotic process involved in development(GO:1904748)
0.1 0.3 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.1 0.2 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.1 0.3 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475)
0.1 0.3 GO:0060263 regulation of respiratory burst(GO:0060263)
0.1 0.3 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.5 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.2 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.2 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.2 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.3 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.3 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.5 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.2 GO:0042117 monocyte activation(GO:0042117)
0.0 0.5 GO:0002920 regulation of humoral immune response(GO:0002920)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.3 GO:1904377 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.0 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.3 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.5 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.0 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.0 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.2 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.0 GO:0048548 regulation of pinocytosis(GO:0048548)
0.0 0.3 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.0 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1902622 regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0010954 positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.0 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0002467 germinal center formation(GO:0002467)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.2 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.2 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0034227 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.1 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.0 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 0.0 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.0 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.0 GO:2000193 positive regulation of fatty acid transport(GO:2000193)
0.0 0.0 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.1 GO:0044110 growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126) negative regulation of growth of symbiont in host(GO:0044130) modulation of growth of symbiont involved in interaction with host(GO:0044144) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:0060413 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.0 GO:0032375 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0 0.0 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.0 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.0 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.0 GO:0048799 organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.8 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.6 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0009268 response to pH(GO:0009268)
0.0 0.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.0 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.4 GO:0042552 myelination(GO:0042552)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.2 GO:0042992 negative regulation of transcription factor import into nucleus(GO:0042992)
0.0 0.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0042401 polyamine biosynthetic process(GO:0006596) cellular biogenic amine biosynthetic process(GO:0042401)
0.0 0.0 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.0 GO:0010523 negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0 0.2 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.2 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0002823 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:0070820 tertiary granule(GO:0070820)
0.1 0.3 GO:0043218 compact myelin(GO:0043218)
0.1 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.2 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.0 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0043230 extracellular organelle(GO:0043230)
0.0 0.0 GO:0016580 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.3 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.1 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.3 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.5 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0046979 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.0 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.2 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.0 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.0 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.0 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID EPO PATHWAY EPO signaling pathway
0.0 0.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.1 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.2 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)