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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NKX1-2_RAX

Z-value: 0.77

Motif logo

Transcription factors associated with NKX1-2_RAX

Gene Symbol	Gene ID	Gene Info
NKX1-2 Ensembl NCBI GeneCards UniProt	ENSG00000229544.6	NKX1-2
RAX Ensembl NCBI GeneCards UniProt	ENSG00000134438.9	RAX

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
NKX1-2	chr10_126137746_126137897	729	0.569900	0.19	6.2e-01	Click!
NKX1-2	chr10_126137495_126137646	980	0.420831	0.18	6.4e-01	Click!
NKX1-2	chr10_126138132_126138283	343	0.841994	-0.11	7.7e-01	Click!
NKX1-2	chr10_126138368_126138519	107	0.957241	-0.06	8.9e-01	Click!
RAX	chr18_56939565_56939853	908	0.623630	0.89	1.2e-03	Click!
RAX	chr18_56936630_56936781	3912	0.253613	0.52	1.5e-01	Click!
RAX	chr18_56932228_56932379	8314	0.215386	0.50	1.7e-01	Click!
RAX	chr18_56939924_56940075	618	0.760815	-0.20	6.1e-01	Click!
RAX	chr18_56936216_56936367	4326	0.245541	-0.13	7.3e-01	Click!

Activity of the NKX1-2_RAX motif across conditions

Conditions sorted by the z-value of the NKX1-2_RAX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_87799796_87800719	0.94	LMO4	LIM domain only 4	2906	0.4
chr4_157891142_157892336	0.89	PDGFC	platelet derived growth factor C	316	0.91
chr2_207998546_207999225	0.74	KLF7	Kruppel-like factor 7 (ubiquitous)	24	0.98
chr1_68697735_68698156	0.69	WLS	wntless Wnt ligand secretion mediator	18	0.98
chr1_196577911_196578299	0.63	KCNT2	potassium channel, subfamily T, member 2	250	0.94
chr8_89311514_89311910	0.62	RP11-586K2.1		27353	0.2
chr9_13278507_13279169	0.60	RP11-272P10.2		348	0.67
chr8_116675050_116675578	0.57	TRPS1	trichorhinophalangeal syndrome I	1409	0.6
chr6_163817634_163818149	0.53	QKI	QKI, KH domain containing, RNA binding	17784	0.29
chr1_225842736_225843127	0.53	ENAH	enabled homolog (Drosophila)	2087	0.34
chr12_54418548_54418910	0.52	HOXC6	homeobox C6	3413	0.09
chr3_112356169_112356393	0.51	CCDC80	coiled-coil domain containing 80	663	0.77
chr4_15471989_15472140	0.49	CC2D2A	coiled-coil and C2 domain containing 2A	427	0.85
chr8_37350646_37351319	0.48	RP11-150O12.6		23557	0.24
chr5_82767889_82768074	0.47	VCAN	versican	237	0.96
chr3_33318777_33319866	0.46	FBXL2	F-box and leucine-rich repeat protein 2	353	0.91
chr4_77610213_77610516	0.46	AC107072.2		51588	0.12
chr12_89033220_89033386	0.46	ENSG00000252850	.	57887	0.14
chr3_87038506_87038677	0.46	VGLL3	vestigial like 3 (Drosophila)	1261	0.64
chr15_99297407_99297593	0.45	ENSG00000264480	.	30155	0.19
chr8_56805751_56805987	0.45	RP11-318K15.2		285	0.88
chr9_96819103_96819334	0.45	PTPDC1	protein tyrosine phosphatase domain containing 1	26142	0.21
chr2_128492018_128492224	0.43	SFT2D3	SFT2 domain containing 3	33524	0.13
chr6_148663224_148663375	0.43	SASH1	SAM and SH3 domain containing 1	430	0.89
chr5_51565820_51566012	0.43	CTD-2203A3.1	Uncharacterized protein	260267	0.02
chr10_119303944_119304573	0.42	EMX2OS	EMX2 opposite strand/antisense RNA	321	0.88
chr22_36232810_36232961	0.42	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	3380	0.35
chr9_16828464_16828715	0.41	BNC2	basonuclin 2	3697	0.36
chr10_24754741_24755189	0.41	KIAA1217	KIAA1217	495	0.84
chr2_101438663_101438947	0.41	AC092168.2		318	0.86
chr1_182932139_182932350	0.40	ENSG00000264768	.	3534	0.19
chr15_96884556_96884898	0.40	ENSG00000222651	.	8237	0.16
chr20_10502111_10502382	0.40	SLX4IP	SLX4 interacting protein	86295	0.09
chr12_52347769_52348164	0.40	ACVR1B	activin A receptor, type IB	802	0.57
chr11_36252522_36252860	0.39	COMMD9	COMM domain containing 9	58283	0.13
chr8_16622129_16622507	0.39	ENSG00000264092	.	98687	0.08
chr9_22008020_22008450	0.38	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	717	0.61
chr18_53089837_53090372	0.38	TCF4	transcription factor 4	361	0.89
chrX_119691520_119691671	0.38	CUL4B	cullin 4B	2203	0.3
chr9_4137636_4137913	0.38	GLIS3	GLIS family zinc finger 3	7419	0.28
chr6_28616143_28617086	0.38	ENSG00000272278	.	572	0.79
chr6_132437274_132437503	0.37	ENSG00000265669	.	985	0.69
chr10_4284322_4284712	0.37	ENSG00000207124	.	272627	0.02
chr3_134050593_134051228	0.37	AMOTL2	angiomotin like 2	39844	0.16
chr2_188418561_188419245	0.37	AC007319.1		27	0.69
chr1_79043181_79043547	0.37	IFI44L	interferon-induced protein 44-like	42243	0.17
chr12_19358284_19358561	0.37	PLEKHA5	pleckstrin homology domain containing, family A member 5	163	0.96
chr10_12746098_12746480	0.36	ENSG00000221331	.	21063	0.25
chr3_79066759_79066910	0.36	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	860	0.75
chr17_21415164_21415422	0.35	RP11-822E23.2		20942	0.2
chr10_114552786_114553214	0.35	RP11-57H14.4		30249	0.21
chr3_112362286_112362437	0.35	CCDC80	coiled-coil domain containing 80	2214	0.38
chr7_55166552_55166703	0.35	EGFR	epidermal growth factor receptor	10789	0.29
chr1_246198663_246198916	0.35	RP11-83A16.1		1936	0.45
chr20_43965593_43965922	0.35	SDC4	syndecan 4	11307	0.11
chr19_13127591_13127981	0.34	CTC-239J10.1		2461	0.15
chr10_34149976_34150160	0.34	ENSG00000199200	.	340934	0.01
chr10_115032925_115033406	0.34	ENSG00000238380	.	80019	0.11
chr16_62068318_62068835	0.34	CDH8	cadherin 8, type 2	462	0.9
chr1_177953163_177953341	0.34	SEC16B	SEC16 homolog B (S. cerevisiae)	13904	0.3
chr5_154033985_154034136	0.33	ENSG00000221552	.	31276	0.14
chr9_94178893_94179044	0.33	NFIL3	nuclear factor, interleukin 3 regulated	7176	0.29
chr5_35851300_35851523	0.33	IL7R	interleukin 7 receptor	1386	0.45
chr20_36040358_36040543	0.33	SRC	v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog	27897	0.21
chr2_151340168_151340387	0.32	RND3	Rho family GTPase 3	1619	0.57
chr20_56706361_56706780	0.32	C20orf85	chromosome 20 open reading frame 85	19390	0.21
chr8_58653688_58653839	0.32	ENSG00000252057	.	184619	0.03
chr7_33746403_33746586	0.32	RP11-89N17.1	HCG1643653; Uncharacterized protein	19099	0.23
chr18_3791000_3791154	0.32	RP11-874J12.3		19647	0.17
chr1_10511084_10511235	0.32	CORT	cortistatin	1188	0.31
chr12_115135696_115136278	0.32	TBX3	T-box 3	14018	0.21
chr6_106474855_106475295	0.32	PRDM1	PR domain containing 1, with ZNF domain	59120	0.13
chr5_14153831_14154379	0.31	TRIO	trio Rho guanine nucleotide exchange factor	10276	0.32
chr6_27515697_27516098	0.31	ENSG00000206671	.	48294	0.13
chr17_66700653_66700804	0.31	ENSG00000263690	.	61972	0.13
chr5_148786412_148786563	0.31	ENSG00000208035	.	21994	0.11
chr19_39149984_39150227	0.31	ACTN4	actinin, alpha 4	11727	0.12
chr13_102107295_102107446	0.31	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	2352	0.4
chr5_97790329_97790704	0.31	ENSG00000223053	.	184419	0.03
chr14_54816147_54816359	0.31	CDKN3	cyclin-dependent kinase inhibitor 3	47420	0.17
chr3_32001454_32001950	0.31	OSBPL10	oxysterol binding protein-like 10	21090	0.19
chr5_131750481_131750657	0.30	C5orf56	chromosome 5 open reading frame 56	3888	0.16
chr3_114169976_114170457	0.30	ZBTB20	zinc finger and BTB domain containing 20	3314	0.33
chr6_6005898_6006049	0.30	NRN1	neuritin 1	1227	0.56
chr4_169769029_169769180	0.30	RP11-635L1.3		15016	0.19
chr14_74191037_74191188	0.30	PNMA1	paraneoplastic Ma antigen 1	9984	0.11
chr5_64438498_64438671	0.29	ENSG00000207439	.	19388	0.29
chr7_79766032_79766269	0.29	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	1079	0.66
chr3_116583114_116583333	0.29	ENSG00000265433	.	14009	0.25
chr7_116312981_116313724	0.29	MET	met proto-oncogene	893	0.68
chr2_213403391_213403972	0.29	ERBB4	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4	116	0.98
chr1_198873285_198873436	0.29	ENSG00000207759	.	45078	0.17
chr9_104248314_104249564	0.29	TMEM246	transmembrane protein 246	460	0.79
chr12_94580963_94581249	0.29	RP11-74K11.2		1286	0.5
chr8_127837007_127837644	0.29	ENSG00000212451	.	153558	0.04
chr14_101867418_101867569	0.29	ENSG00000258498	.	159266	0.02
chr7_80545378_80545529	0.29	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	3046	0.41
chr4_134070427_134071051	0.29	PCDH10	protocadherin 10	269	0.96
chr4_20258902_20259191	0.29	SLIT2	slit homolog 2 (Drosophila)	2503	0.44
chrX_34671991_34672311	0.28	TMEM47	transmembrane protein 47	3254	0.41
chr7_128171824_128173030	0.28	RP11-274B21.1		1279	0.43
chr2_63926212_63926391	0.28	ENSG00000221085	.	3632	0.34
chr5_92943123_92943644	0.28	ENSG00000251725	.	13111	0.2
chr12_66286178_66286489	0.28	RP11-366L20.2	Uncharacterized protein	10386	0.18
chr3_88191159_88191414	0.28	ZNF654	zinc finger protein 654	3032	0.24
chr7_92327766_92328157	0.28	ENSG00000206763	.	3167	0.33
chr22_46476561_46476775	0.28	FLJ27365	hsa-mir-4763	476	0.66
chr4_54063057_54063462	0.28	ENSG00000207385	.	68475	0.13
chr8_79468522_79468695	0.28	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	34858	0.19
chr11_95646755_95646928	0.28	MTMR2	myotubularin related protein 2	600	0.82
chr5_174178214_174178699	0.28	ENSG00000266890	.	281	0.94
chr1_150135684_150135897	0.28	PLEKHO1	pleckstrin homology domain containing, family O member 1	6667	0.15
chr3_154798803_154798954	0.28	MME	membrane metallo-endopeptidase	125	0.98
chr9_89738235_89738413	0.28	C9orf170	chromosome 9 open reading frame 170	25235	0.26
chr17_42214986_42215221	0.27	ENSG00000212446	.	1746	0.18
chr3_114477857_114478359	0.27	ZBTB20	zinc finger and BTB domain containing 20	10	0.99
chr2_153349112_153349263	0.27	FMNL2	formin-like 2	126905	0.06
chr5_3597777_3597928	0.27	IRX1	iroquois homeobox 1	1684	0.41
chr1_186072218_186072510	0.27	HMCN1	hemicentin 1	68155	0.12
chr3_59101471_59101696	0.27	C3orf67	chromosome 3 open reading frame 67	65773	0.15
chr15_37179413_37179956	0.27	ENSG00000212511	.	34843	0.22
chr22_36232318_36232521	0.27	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	3846	0.33
chr20_48319819_48319972	0.27	B4GALT5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	10520	0.19
chr14_81484576_81484774	0.27	CEP128	centrosomal protein 128kDa	58827	0.14
chr3_87036535_87037613	0.27	VGLL3	vestigial like 3 (Drosophila)	2778	0.42
chr7_116142190_116142403	0.27	CAV2	caveolin 2	2462	0.22
chr7_70201396_70202343	0.27	AUTS2	autism susceptibility candidate 2	7744	0.34
chrX_73069883_73070423	0.27	RP13-216E22.5		119167	0.06
chr15_96903910_96904291	0.27	AC087477.1	Uncharacterized protein	387	0.85
chr2_33662989_33663140	0.27	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	1673	0.49
chr4_121990444_121990801	0.27	NDNF	neuron-derived neurotrophic factor	2534	0.31
chr3_193856720_193856967	0.26	HES1	hes family bHLH transcription factor 1	2909	0.25
chr2_216795737_216796089	0.26	ENSG00000212055	.	52271	0.15
chr1_88319546_88319697	0.26	ENSG00000199318	.	400565	0.01
chr9_97563812_97563963	0.26	C9orf3	chromosome 9 open reading frame 3	1429	0.41
chr5_57751342_57751690	0.26	PLK2	polo-like kinase 2	4571	0.26
chr8_8468799_8468974	0.26	ENSG00000264445	.	22088	0.2
chr18_52973612_52973763	0.26	TCF4	transcription factor 4	3830	0.35
chr1_245461989_245462162	0.26	RP11-62I21.1		64272	0.12
chr4_141013667_141013926	0.26	RP11-392B6.1		35373	0.19
chr12_80794329_80794553	0.26	PTPRQ	protein tyrosine phosphatase, receptor type, Q	5333	0.26
chr4_54187854_54188041	0.26	SCFD2	sec1 family domain containing 2	44281	0.15
chr13_31443551_31443843	0.26	MEDAG	mesenteric estrogen-dependent adipogenesis	36631	0.17
chr5_97726813_97726964	0.25	ENSG00000223053	.	248047	0.02
chr3_174159101_174159924	0.25	NAALADL2	N-acetylated alpha-linked acidic dipeptidase-like 2	735	0.81
chr8_80696427_80696819	0.25	ENSG00000238884	.	15807	0.22
chr3_14211699_14211850	0.25	LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	8084	0.16
chr9_15735359_15735549	0.25	CCDC171	coiled-coil domain containing 171	9049	0.26
chr11_92117878_92118174	0.25	RP11-675M1.2		23316	0.23
chr2_121334386_121334749	0.25	ENSG00000201006	.	74282	0.11
chr10_30744125_30744276	0.25	MAP3K8	mitogen-activated protein kinase kinase kinase 8	16449	0.22
chr14_53509566_53509717	0.25	RP11-368P15.3		6168	0.27
chr7_87974817_87974968	0.25	STEAP4	STEAP family member 4	38686	0.17
chr6_5471426_5471612	0.25	RP1-232P20.1		13211	0.27
chr4_71997150_71997347	0.24	SLC4A4	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	55755	0.16
chr9_110818837_110819103	0.24	ENSG00000222459	.	137711	0.05
chr8_32085203_32085460	0.24	NRG1-IT2	NRG1 intronic transcript 2 (non-protein coding)	6887	0.22
chr14_75896980_75897330	0.24	JDP2	Jun dimerization protein 2	1682	0.35
chr8_57086542_57086822	0.24	PLAG1	pleiomorphic adenoma gene 1	37156	0.12
chr6_85470567_85470756	0.24	TBX18	T-box 18	2412	0.42
chr14_31887812_31887963	0.24	CTD-2213F21.2		1605	0.27
chr11_697541_698020	0.24	TMEM80	transmembrane protein 80	1975	0.14
chr21_17909068_17909746	0.24	ENSG00000207638	.	2002	0.33
chr11_15135960_15136328	0.24	INSC	inscuteable homolog (Drosophila)	340	0.92
chr3_120215962_120216316	0.24	FSTL1	follistatin-like 1	46039	0.16
chr9_77757026_77757296	0.24	ENSG00000200041	.	39376	0.14
chr6_3473109_3473260	0.24	SLC22A23	solute carrier family 22, member 23	15928	0.27
chr2_66663569_66663965	0.24	MEIS1	Meis homeobox 1	758	0.57
chr6_136570446_136570737	0.24	MTFR2	mitochondrial fission regulator 2	841	0.63
chr1_178065779_178065930	0.24	RASAL2	RAS protein activator like 2	2578	0.43
chr12_50748152_50748528	0.24	FAM186A	family with sequence similarity 186, member A	3672	0.22
chr2_223916824_223917105	0.24	KCNE4	potassium voltage-gated channel, Isk-related family, member 4	102	0.98
chr3_106060605_106060757	0.24	ENSG00000200610	.	174063	0.04
chr7_7545818_7546068	0.24	COL28A1	collagen, type XXVIII, alpha 1	29541	0.21
chr15_96886136_96886425	0.23	ENSG00000222651	.	9790	0.16
chr9_81871858_81872685	0.23	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	314417	0.01
chr15_42749459_42749764	0.23	ZNF106	zinc finger protein 106	100	0.96
chr4_120446718_120446900	0.23	PDE5A	phosphodiesterase 5A, cGMP-specific	6555	0.24
chr17_10039283_10039434	0.23	AC000003.2	CDNA FLJ25865 fis, clone CBR01927	9473	0.21
chr12_47470653_47470804	0.23	PCED1B	PC-esterase domain containing 1B	2658	0.29
chr12_53995183_53995708	0.23	ATF7	activating transcription factor 7	640	0.67
chr21_35678304_35678597	0.23	ENSG00000266007	.	1020	0.57
chr6_45545466_45545617	0.23	ENSG00000252738	.	68300	0.13
chr12_26277242_26278053	0.23	BHLHE41	basic helix-loop-helix family, member e41	413	0.76
chr17_57703305_57703456	0.23	CLTC	clathrin, heavy chain (Hc)	6087	0.21
chr9_126331371_126331654	0.23	ENSG00000222722	.	16224	0.24
chr15_35950174_35950564	0.23	DPH6	diphthamine biosynthesis 6	111976	0.07
chr11_46237993_46238166	0.23	CTD-2589M5.4		58019	0.1
chr16_83583521_83583672	0.23	ENSG00000263785	.	41645	0.18
chr7_82070146_82070432	0.23	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1	2742	0.43
chr18_6730820_6730971	0.23	ARHGAP28	Rho GTPase activating protein 28	853	0.47
chr5_172665530_172665713	0.23	NKX2-5	NK2 homeobox 5	3261	0.23
chr11_27861058_27861209	0.22	RP11-587D21.4		38062	0.2
chr3_152019172_152019323	0.22	MBNL1	muscleblind-like splicing regulator 1	1260	0.51
chr14_88921501_88921652	0.22	PTPN21	protein tyrosine phosphatase, non-receptor type 21	14384	0.17
chr12_50635075_50635226	0.22	ENSG00000221604	.	7155	0.13
chr13_52360273_52360424	0.22	DHRS12	dehydrogenase/reductase (SDR family) member 12	17886	0.19
chr10_29010987_29011704	0.22	ENSG00000201001	.	38387	0.14
chr18_52495652_52496658	0.22	RAB27B	RAB27B, member RAS oncogene family	725	0.77
chr6_116834038_116834189	0.22	TRAPPC3L	trafficking protein particle complex 3-like	607	0.55

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX1-2_RAX

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.1	0.4	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.4	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.2	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.2	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.2	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.2	GO:0060677	ureteric bud elongation(GO:0060677)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.2	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.2	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.4	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.3	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	1.0	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.2	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.2	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.0	GO:0060027	convergent extension involved in gastrulation(GO:0060027)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.2	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.5	GO:0008347	glial cell migration(GO:0008347)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.2	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0060841	venous blood vessel development(GO:0060841)
0.0	0.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0061430	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.8	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.0	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0	0.1	GO:0072081	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.8	GO:0048813	dendrite morphogenesis(GO:0048813)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.0	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.9	GO:0001843	neural tube closure(GO:0001843)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	0.6	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.0	GO:0090109	regulation of focal adhesion assembly(GO:0051893) negative regulation of focal adhesion assembly(GO:0051895) regulation of cell-substrate junction assembly(GO:0090109) regulation of cell junction assembly(GO:1901888) negative regulation of cell junction assembly(GO:1901889) regulation of adherens junction organization(GO:1903391) negative regulation of adherens junction organization(GO:1903392)
0.0	0.0	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0042663	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.0	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.4	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.2	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.2	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0010667	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.0	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.0	GO:0003307	regulation of Wnt signaling pathway involved in heart development(GO:0003307)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.0	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.0	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.0	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.0	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.0	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.0	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.0	GO:0060754	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.0	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.0	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.0	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.0	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0007320	insemination(GO:0007320)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.0	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.6	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.2	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.2	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.4	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.0	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.0	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.4	GO:0036064	ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.3	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.9	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1	0.6	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	0.6	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.8	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.3	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.6	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.2	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.3	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.0	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.2	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.0	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.0	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.0	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.0	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.8	PID SHP2 PATHWAY	SHP2 signaling
0.7	NABA COLLAGENS	Genes encoding collagen proteins
0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.4	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.6	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.0	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors