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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NKX2-1

Z-value: 1.59

Motif logo

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Transcription factors associated with NKX2-1

Gene Symbol Gene ID Gene Info
ENSG00000136352.13 NKX2-1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NKX2-1chr14_36989860_36990554530.961986-0.627.4e-02Click!
NKX2-1chr14_36988610_369888441710.592695-0.599.5e-02Click!
NKX2-1chr14_37011598_37011749213190.135766-0.571.1e-01Click!
NKX2-1chr14_36989189_36989396470.937388-0.501.7e-01Click!
NKX2-1chr14_36988876_36989053660.878462-0.088.4e-01Click!

Activity of the NKX2-1 motif across conditions

Conditions sorted by the z-value of the NKX2-1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_263385_263906 5.41 AC108004.3

169
0.93
chr19_3178230_3178381 0.96 S1PR4
sphingosine-1-phosphate receptor 4
431
0.74
chr1_161038546_161039545 0.91 ARHGAP30
Rho GTPase activating protein 30
411
0.65
chr6_108144289_108144729 0.68 SCML4
sex comb on midleg-like 4 (Drosophila)
1007
0.66
chr12_7060685_7060854 0.67 PTPN6
protein tyrosine phosphatase, non-receptor type 6
231
0.78
chrX_131121415_131121857 0.65 ENSG00000265686
.
9237
0.22
chr11_1874347_1875032 0.65 LSP1
lymphocyte-specific protein 1
489
0.65
chr6_37140965_37141167 0.63 PIM1
pim-1 oncogene
3087
0.24
chr2_68992950_68993127 0.60 ARHGAP25
Rho GTPase activating protein 25
8895
0.25
chr5_169065291_169065442 0.60 DOCK2
dedicator of cytokinesis 2
1115
0.6
chr1_66801936_66802454 0.58 PDE4B
phosphodiesterase 4B, cAMP-specific
4323
0.35
chr3_71833648_71834232 0.58 PROK2
prokineticin 2
272
0.92
chr17_72747101_72747890 0.57 MIR3615
microRNA 3615
2444
0.14
chr7_150148744_150149359 0.57 GIMAP8
GTPase, IMAP family member 8
1333
0.41
chr2_202126695_202126946 0.56 CASP8
caspase 8, apoptosis-related cysteine peptidase
141
0.96
chr12_57873084_57873440 0.55 ARHGAP9
Rho GTPase activating protein 9
153
0.89
chr2_69002223_69002932 0.55 ARHGAP25
Rho GTPase activating protein 25
505
0.84
chr10_70849708_70849969 0.55 SRGN
serglycin
1964
0.33
chr17_56408975_56409725 0.54 MIR142
microRNA 142
519
0.63
chrX_77581417_77581703 0.53 CYSLTR1
cysteinyl leukotriene receptor 1
1420
0.59
chr19_55765720_55766271 0.53 PPP6R1
protein phosphatase 6, regulatory subunit 1
1142
0.27
chr6_42014851_42015002 0.52 CCND3
cyclin D3
1498
0.33
chr2_96922700_96922878 0.51 TMEM127
transmembrane protein 127
3544
0.17
chr14_93119065_93119528 0.51 RIN3
Ras and Rab interactor 3
450
0.88
chrX_118819066_118819466 0.50 SEPT6
septin 6
7526
0.18
chr2_202098499_202098878 0.50 CASP8
caspase 8, apoptosis-related cysteine peptidase
459
0.82
chr22_18258862_18259013 0.50 BID
BH3 interacting domain death agonist
1506
0.39
chr20_30651395_30651546 0.49 HCK
hemopoietic cell kinase
11406
0.12
chr9_117145878_117146140 0.47 AKNA
AT-hook transcription factor
4234
0.24
chr8_142248690_142248841 0.47 SLC45A4
solute carrier family 45, member 4
8318
0.15
chr10_26770074_26770395 0.47 ENSG00000199733
.
28284
0.21
chr19_14551433_14551660 0.46 PKN1
protein kinase N1
474
0.7
chr2_175497594_175497986 0.46 WIPF1
WAS/WASL interacting protein family, member 1
1517
0.45
chr2_99080716_99081105 0.46 INPP4A
inositol polyphosphate-4-phosphatase, type I, 107kDa
19497
0.22
chr2_198171190_198171625 0.46 ANKRD44
ankyrin repeat domain 44
4104
0.18
chr2_240162672_240162823 0.45 HDAC4
histone deacetylase 4
49995
0.11
chr20_4794500_4794911 0.45 RASSF2
Ras association (RalGDS/AF-6) domain family member 2
1064
0.55
chr14_93118654_93119048 0.44 RIN3
Ras and Rab interactor 3
5
0.99
chr16_30484007_30484505 0.44 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
184
0.81
chr10_119590274_119590549 0.44 RP11-354M20.3

186587
0.03
chr8_133772203_133772517 0.44 TMEM71
transmembrane protein 71
434
0.83
chr9_273119_273416 0.43 DOCK8
dedicator of cytokinesis 8
197
0.59
chr11_63656035_63656583 0.42 MARK2
MAP/microtubule affinity-regulating kinase 2
141
0.94
chr2_68964300_68964451 0.41 ARHGAP25
Rho GTPase activating protein 25
2361
0.38
chr9_117690832_117691467 0.41 TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
1548
0.52
chr8_37754904_37755445 0.41 RAB11FIP1
RAB11 family interacting protein 1 (class I)
1798
0.27
chr9_128586563_128586792 0.41 PBX3
pre-B-cell leukemia homeobox 3
40873
0.21
chr8_134085908_134086059 0.41 SLA
Src-like-adaptor
13380
0.24
chr10_11206019_11206557 0.41 CELF2
CUGBP, Elav-like family member 2
705
0.72
chr1_45189703_45189968 0.41 ENSG00000199377
.
2261
0.15
chr16_28996496_28996848 0.41 LAT
linker for activation of T cells
11
0.94
chr6_42014486_42014637 0.40 CCND3
cyclin D3
1863
0.28
chr6_25036389_25036540 0.40 ENSG00000244618
.
4954
0.19
chr8_27185487_27185714 0.39 PTK2B
protein tyrosine kinase 2 beta
1260
0.49
chr3_33061158_33061309 0.39 CCR4
chemokine (C-C motif) receptor 4
68167
0.09
chr19_42057824_42058331 0.39 CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
2191
0.27
chr7_72648551_72648702 0.38 NCF1B
neutrophil cytosolic factor 1B pseudogene
13945
0.16
chr21_39644113_39644319 0.38 KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
1
0.99
chr13_30950425_30950835 0.37 KATNAL1
katanin p60 subunit A-like 1
69009
0.11
chr1_226830744_226831144 0.37 ITPKB-IT1
ITPKB intronic transcript 1 (non-protein coding)
16427
0.2
chr10_30316643_30316960 0.37 KIAA1462
KIAA1462
31652
0.24
chr2_158300794_158300945 0.37 CYTIP
cytohesin 1 interacting protein
215
0.94
chr8_125576429_125576668 0.37 MTSS1
metastasis suppressor 1
1420
0.36
chr17_80817564_80818630 0.37 TBCD
tubulin folding cofactor D
173
0.94
chr10_22622036_22622322 0.37 BMI1
BMI1 polycomb ring finger oncogene
6731
0.15
chr3_41159090_41159342 0.37 CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
77112
0.12
chr6_16704232_16705187 0.36 RP1-151F17.1

56660
0.15
chr9_134145569_134145886 0.36 FAM78A
family with sequence similarity 78, member A
153
0.95
chr19_17202718_17202884 0.36 CTD-2528A14.5

7316
0.12
chr2_233925739_233925978 0.36 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
669
0.7
chr1_231748956_231749347 0.36 LINC00582
long intergenic non-protein coding RNA 582
1315
0.46
chr16_29756930_29757303 0.35 C16orf54
chromosome 16 open reading frame 54
211
0.73
chr17_33568871_33569147 0.35 RP11-799D4.4

973
0.36
chr8_21917643_21917901 0.35 DMTN
dematin actin binding protein
1038
0.39
chr14_105530971_105531214 0.35 GPR132
G protein-coupled receptor 132
675
0.7
chr19_16254556_16255035 0.35 HSH2D
hematopoietic SH2 domain containing
249
0.88
chr19_4089284_4089443 0.35 MAP2K2
mitogen-activated protein kinase kinase 2
11682
0.11
chr7_150212658_150212835 0.35 GIMAP7
GTPase, IMAP family member 7
828
0.63
chr1_161037877_161038104 0.35 ARHGAP30
Rho GTPase activating protein 30
1466
0.19
chr17_4389201_4389708 0.34 RP13-580F15.2

194
0.92
chr6_24920065_24920216 0.34 FAM65B
family with sequence similarity 65, member B
8945
0.23
chr5_176935395_176936034 0.34 DOK3
docking protein 3
1113
0.32
chr6_35268574_35268725 0.34 DEF6
differentially expressed in FDCP 6 homolog (mouse)
3020
0.24
chr17_56410108_56410593 0.34 MIR142
microRNA 142
481
0.66
chr20_47914108_47914286 0.34 ENSG00000212304
.
16977
0.12
chr3_141218227_141218432 0.34 RASA2
RAS p21 protein activator 2
12438
0.21
chr15_40475830_40476133 0.34 BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
22713
0.12
chr1_109188164_109188315 0.34 HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
15438
0.19
chr6_138188643_138189747 0.34 RP11-356I2.4

175
0.8
chr14_91698668_91698819 0.34 CTD-2547L24.3
HCG1816139; Uncharacterized protein
10360
0.16
chr19_3188765_3188950 0.34 NCLN
nicalin
2923
0.17
chr14_100532787_100533367 0.34 EVL
Enah/Vasp-like
303
0.88
chr9_117149358_117150269 0.34 AKNA
AT-hook transcription factor
430
0.85
chr17_72459271_72459541 0.34 CD300A
CD300a molecule
3149
0.19
chr10_30818638_30818892 0.34 ENSG00000239744
.
26068
0.21
chr13_48729935_48730086 0.33 MED4
mediator complex subunit 4
60743
0.11
chr1_26872331_26872899 0.33 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
272
0.88
chr10_82247793_82248042 0.33 TSPAN14
tetraspanin 14
28859
0.16
chr2_240188602_240189192 0.33 ENSG00000265215
.
38260
0.14
chr11_117856643_117857627 0.33 IL10RA
interleukin 10 receptor, alpha
26
0.98
chr10_98416450_98416602 0.33 PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
12842
0.2
chr17_72733506_72734386 0.32 RAB37
RAB37, member RAS oncogene family
575
0.59
chr20_57266602_57266883 0.32 NPEPL1
aminopeptidase-like 1
927
0.53
chr12_25205549_25206037 0.32 LRMP
lymphoid-restricted membrane protein
119
0.97
chr10_129846333_129846652 0.32 PTPRE
protein tyrosine phosphatase, receptor type, E
658
0.81
chr2_10522774_10523051 0.32 HPCAL1
hippocalcin-like 1
37235
0.15
chr10_121297814_121297965 0.32 RGS10
regulator of G-protein signaling 10
1844
0.41
chr12_7061251_7061427 0.32 PTPN6
protein tyrosine phosphatase, non-receptor type 6
801
0.31
chr1_26644827_26645344 0.32 UBXN11
UBX domain protein 11
231
0.76
chr5_39185986_39186142 0.32 FYB
FYN binding protein
17065
0.25
chr11_72449633_72449911 0.31 ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
11599
0.12
chr15_75078612_75078763 0.31 CSK
c-src tyrosine kinase
2198
0.18
chr19_1069559_1069710 0.31 HMHA1
histocompatibility (minor) HA-1
1586
0.2
chr14_22959669_22959820 0.31 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
3573
0.13
chr6_131894379_131894530 0.31 ARG1
arginase 1
89
0.97
chr17_29814991_29815971 0.30 RAB11FIP4
RAB11 family interacting protein 4 (class II)
355
0.83
chr9_139924646_139924964 0.30 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
2065
0.1
chr19_2892956_2893107 0.30 ZNF57
zinc finger protein 57
7865
0.11
chr11_128595318_128595476 0.30 SENCR
smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
29479
0.16
chr20_19285668_19285819 0.30 RP5-1027G4.3

20503
0.2
chr9_95727852_95728104 0.30 FGD3
FYVE, RhoGEF and PH domain containing 3
1735
0.41
chr9_36151556_36151950 0.30 GLIPR2
GLI pathogenesis-related 2
15011
0.17
chr16_88771466_88772351 0.30 RNF166
ring finger protein 166
762
0.31
chr14_22919067_22919218 0.30 TRDD3
T cell receptor delta diversity 3
1037
0.37
chr19_15574418_15574723 0.30 RASAL3
RAS protein activator like 3
812
0.5
chr11_65409143_65409294 0.29 SIPA1
signal-induced proliferation-associated 1
919
0.33
chr11_74986437_74986718 0.29 ARRB1
arrestin, beta 1
3166
0.18
chr7_150415780_150415950 0.29 GIMAP1
GTPase, IMAP family member 1
2220
0.26
chr17_4402676_4403013 0.29 AC118754.4

125
0.88
chr6_41167766_41167943 0.29 TREML2
triggering receptor expressed on myeloid cells-like 2
1078
0.4
chr16_30104448_30104599 0.29 TBX6
T-box 6
1315
0.2
chr9_130540814_130540998 0.29 SH2D3C
SH2 domain containing 3C
114
0.92
chr17_43487096_43487739 0.29 ARHGAP27
Rho GTPase activating protein 27
335
0.82
chr4_6912691_6912996 0.28 TBC1D14
TBC1 domain family, member 14
868
0.61
chr6_16707242_16707393 0.28 RP1-151F17.1

54052
0.15
chr17_262343_262585 0.28 AC108004.3

1350
0.32
chr3_111261315_111261845 0.28 CD96
CD96 molecule
583
0.82
chr19_17516551_17516849 0.28 MVB12A
multivesicular body subunit 12A
150
0.6
chr1_198648918_198649184 0.28 RP11-553K8.5

12861
0.25
chr2_60784499_60784860 0.28 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
3977
0.29
chr13_31309749_31309959 0.28 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
209
0.96
chr17_33640471_33640814 0.28 SLFN11
schlafen family member 11
39508
0.12
chr5_40849557_40849708 0.28 CARD6
caspase recruitment domain family, member 6
8222
0.15
chrX_129225529_129225680 0.28 ELF4
E74-like factor 4 (ets domain transcription factor)
18732
0.19
chr22_19349038_19349189 0.28 ENSG00000244296
.
4176
0.19
chr12_94640073_94640224 0.28 PLXNC1
plexin C1
8146
0.19
chr1_225655628_225655947 0.28 RP11-496N12.6

2742
0.3
chr10_73512307_73512458 0.28 C10orf54
chromosome 10 open reading frame 54
5005
0.22
chr8_27183780_27184189 0.27 PTK2B
protein tyrosine kinase 2 beta
356
0.89
chr21_37538870_37539021 0.27 DOPEY2
dopey family member 2
2112
0.23
chr7_50345819_50346403 0.27 IKZF1
IKAROS family zinc finger 1 (Ikaros)
1733
0.5
chr7_37382547_37382746 0.27 ELMO1
engulfment and cell motility 1
137
0.97
chr7_73624408_73624729 0.27 LAT2
linker for activation of T cells family, member 2
215
0.92
chr16_3116517_3116777 0.27 IL32
interleukin 32
834
0.3
chr2_63287244_63287598 0.27 OTX1
orthodenticle homeobox 1
9484
0.23
chr5_131756238_131756389 0.27 AC116366.5

5833
0.14
chr20_57738915_57739179 0.27 ZNF831
zinc finger protein 831
27028
0.21
chr2_101197581_101197746 0.27 ENSG00000238328
.
3732
0.2
chr7_99954721_99954872 0.27 PILRB
paired immunoglobin-like type 2 receptor beta
207
0.86
chr11_1872722_1872911 0.27 LSP1
lymphocyte-specific protein 1
1384
0.25
chr10_73514142_73514368 0.27 C10orf54
chromosome 10 open reading frame 54
3132
0.25
chr12_4377755_4378334 0.27 CCND2
cyclin D2
4894
0.19
chr10_75625845_75625996 0.27 CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
5308
0.13
chr12_51713121_51713481 0.27 BIN2
bridging integrator 2
4598
0.18
chr6_35270264_35270539 0.26 DEF6
differentially expressed in FDCP 6 homolog (mouse)
4772
0.2
chr16_89428306_89428472 0.26 ANKRD11
ankyrin repeat domain 11
32995
0.1
chr7_50415328_50415483 0.26 IKZF1
IKAROS family zinc finger 1 (Ikaros)
48160
0.16
chr1_209943452_209943666 0.26 TRAF3IP3
TRAF3 interacting protein 3
1599
0.29
chr22_39152724_39153020 0.26 SUN2
Sad1 and UNC84 domain containing 2
867
0.37
chr14_23385013_23385164 0.26 RBM23
RNA binding motif protein 23
1677
0.16
chr1_111173785_111173949 0.26 KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
229
0.93
chr12_739807_740337 0.26 RP11-218M22.1

15
0.97
chr2_70203509_70203660 0.26 PCBP1-AS1
PCBP1 antisense RNA 1
11678
0.14
chr13_41557045_41557196 0.26 ELF1
E74-like factor 1 (ets domain transcription factor)
702
0.71
chr17_80063977_80064793 0.26 CCDC57
coiled-coil domain containing 57
4659
0.1
chr19_8641491_8641716 0.26 MYO1F
myosin IF
719
0.54
chr3_196417091_196417380 0.26 ENSG00000201441
.
18600
0.11
chr11_6766181_6766335 0.26 GVINP1
GTPase, very large interferon inducible pseudogene 1
23147
0.11
chrX_124337019_124337170 0.26 ENSG00000263886
.
84531
0.11
chr6_35266459_35266895 0.25 DEF6
differentially expressed in FDCP 6 homolog (mouse)
1048
0.51
chr3_107843459_107843610 0.25 CD47
CD47 molecule
33662
0.22
chr14_93570056_93570236 0.25 ITPK1
inositol-tetrakisphosphate 1-kinase
11471
0.19
chr1_9713633_9713784 0.25 C1orf200
chromosome 1 open reading frame 200
936
0.49
chr12_132469658_132469809 0.25 ENSG00000271905
.
16587
0.15
chr8_48421782_48421933 0.25 RP11-697N18.4

18102
0.25
chr19_16704917_16705068 0.25 CTD-3222D19.5

6196
0.09
chr1_157789533_157789809 0.25 FCRL1
Fc receptor-like 1
179
0.95
chr16_28174772_28174923 0.25 XPO6
exportin 6
6375
0.19
chr22_39337620_39337940 0.25 APOBEC3A
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
10976
0.14
chr6_143228096_143228637 0.25 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
37972
0.2
chr18_74766190_74766781 0.25 MBP
myelin basic protein
36751
0.2
chr1_95296828_95296979 0.25 SLC44A3
solute carrier family 44, member 3
10697
0.21
chr2_136890030_136890181 0.25 CXCR4
chemokine (C-X-C motif) receptor 4
14370
0.28
chr22_24016112_24016263 0.24 RGL4
ral guanine nucleotide dissociation stimulator-like 4
14142
0.12
chr10_98479597_98479748 0.24 PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
599
0.77
chr17_7239932_7240900 0.24 ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
507
0.51
chr2_169924168_169924319 0.24 DHRS9
dehydrogenase/reductase (SDR family) member 9
656
0.74
chr5_141062081_141062481 0.24 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
493
0.75
chr3_151915094_151915557 0.24 MBNL1
muscleblind-like splicing regulator 1
70504
0.11
chr7_143532753_143532920 0.24 RP11-61L23.2

468
0.82

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NKX2-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.4 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.3 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.4 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.2 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 0.6 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.2 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.1 GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.1 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.4 GO:0046643 regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.2 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.1 0.2 GO:0006154 adenosine catabolic process(GO:0006154)
0.1 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 1.2 GO:0045576 mast cell activation(GO:0045576)
0.1 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 0.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 0.2 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 1.4 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.7 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.0 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.2 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.2 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0052257 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.2 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.7 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.2 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.0 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.0 0.1 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:1902305 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:0002507 tolerance induction(GO:0002507)
0.0 0.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.2 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.2 GO:2000193 positive regulation of fatty acid transport(GO:2000193)
0.0 0.1 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.2 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.2 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.0 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.2 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.2 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.0 GO:0048291 isotype switching to IgG isotypes(GO:0048291)
0.0 0.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 1.1 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.4 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.1 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0002886 regulation of myeloid leukocyte mediated immunity(GO:0002886)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.0 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.0 0.0 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.0 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.0 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.2 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.0 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.3 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0032816 positive regulation of natural killer cell activation(GO:0032816)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.2 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0032727 interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.4 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0042026 protein refolding(GO:0042026)
0.0 0.9 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.0 GO:0003181 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.0 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.0 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.0 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.0 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.0 GO:0002820 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:1902743 regulation of lamellipodium organization(GO:1902743)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.0 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.0 GO:0090311 regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.0 GO:0072338 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.0 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0098534 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.0 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.0 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.0 GO:0048548 regulation of pinocytosis(GO:0048548)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.1 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0001967 suckling behavior(GO:0001967)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0071636 positive regulation of transforming growth factor beta production(GO:0071636)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.0 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0032367 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0000018 regulation of DNA recombination(GO:0000018)
0.0 0.2 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0045730 respiratory burst(GO:0045730)
0.0 0.0 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.0 GO:1904357 negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.0 0.0 GO:0006863 purine nucleobase transport(GO:0006863)
0.0 0.0 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.0 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.4 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0015851 nucleobase transport(GO:0015851)
0.0 0.1 GO:0006067 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.0 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.2 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.0 GO:0009173 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.0 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.0 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.0 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.2 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.0 GO:0071674 mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0006385 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.0 GO:0016265 obsolete death(GO:0016265)
0.0 0.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.0 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.0 GO:0006983 ER overload response(GO:0006983)
0.0 0.0 GO:0030146 obsolete diuresis(GO:0030146)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.0 GO:0034311 diol metabolic process(GO:0034311)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0 0.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:1903363 negative regulation of cellular protein catabolic process(GO:1903363)
0.0 0.0 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:0033158 regulation of protein import into nucleus, translocation(GO:0033158)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0006734 NADH metabolic process(GO:0006734)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.4 GO:0042629 mast cell granule(GO:0042629)
0.1 1.0 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.3 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.5 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.1 GO:0042588 zymogen granule(GO:0042588)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0030904 retromer complex(GO:0030904)
0.0 0.0 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.0 GO:0030891 VCB complex(GO:0030891)
0.0 1.4 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.5 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0016234 inclusion body(GO:0016234)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0005775 vacuolar lumen(GO:0005775)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.0 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.4 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.5 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.2 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.5 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0019956 chemokine binding(GO:0019956)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.0 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.5 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.0 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 2.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.0 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0051861 glycolipid binding(GO:0051861)
0.0 0.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.0 GO:0005035 death receptor activity(GO:0005035)
0.0 0.0 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.0 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.1 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.0 PID SHP2 PATHWAY SHP2 signaling
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.0 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.0 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus