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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for NKX2-1

Z-value: 1.59

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Transcription factors associated with NKX2-1

Gene Symbol	Gene ID	Gene Info
NKX2-1 Ensembl NCBI GeneCards UniProt	ENSG00000136352.13	NK2 homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr14_36989860_36990554	NKX2-1	53	0.961986	-0.62	7.4e-02	Click!
chr14_36988610_36988844	NKX2-1	171	0.592695	-0.59	9.5e-02	Click!
chr14_37011598_37011749	NKX2-1	21319	0.135766	-0.57	1.1e-01	Click!
chr14_36989189_36989396	NKX2-1	47	0.937388	-0.50	1.7e-01	Click!
chr14_36988876_36989053	NKX2-1	66	0.878462	-0.08	8.4e-01	Click!

Activity of the NKX2-1 motif across conditions

Conditions sorted by the z-value of the NKX2-1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_263385_263906	5.41	AC108004.3		169	0.93
chr19_3178230_3178381	0.96	S1PR4	sphingosine-1-phosphate receptor 4	431	0.74
chr1_161038546_161039545	0.91	ARHGAP30	Rho GTPase activating protein 30	411	0.65
chr6_108144289_108144729	0.68	SCML4	sex comb on midleg-like 4 (Drosophila)	1007	0.66
chr12_7060685_7060854	0.67	PTPN6	protein tyrosine phosphatase, non-receptor type 6	231	0.78
chrX_131121415_131121857	0.65	ENSG00000265686	.	9237	0.22
chr11_1874347_1875032	0.65	LSP1	lymphocyte-specific protein 1	489	0.65
chr6_37140965_37141167	0.63	PIM1	pim-1 oncogene	3087	0.24
chr2_68992950_68993127	0.60	ARHGAP25	Rho GTPase activating protein 25	8895	0.25
chr5_169065291_169065442	0.60	DOCK2	dedicator of cytokinesis 2	1115	0.6
chr1_66801936_66802454	0.58	PDE4B	phosphodiesterase 4B, cAMP-specific	4323	0.35
chr3_71833648_71834232	0.58	PROK2	prokineticin 2	272	0.92
chr17_72747101_72747890	0.57	MIR3615	microRNA 3615	2444	0.14
chr7_150148744_150149359	0.57	GIMAP8	GTPase, IMAP family member 8	1333	0.41
chr2_202126695_202126946	0.56	CASP8	caspase 8, apoptosis-related cysteine peptidase	141	0.96
chr12_57873084_57873440	0.55	ARHGAP9	Rho GTPase activating protein 9	153	0.89
chr2_69002223_69002932	0.55	ARHGAP25	Rho GTPase activating protein 25	505	0.84
chr10_70849708_70849969	0.55	SRGN	serglycin	1964	0.33
chr17_56408975_56409725	0.54	MIR142	microRNA 142	519	0.63
chrX_77581417_77581703	0.53	CYSLTR1	cysteinyl leukotriene receptor 1	1420	0.59
chr19_55765720_55766271	0.53	PPP6R1	protein phosphatase 6, regulatory subunit 1	1142	0.27
chr6_42014851_42015002	0.52	CCND3	cyclin D3	1498	0.33
chr2_96922700_96922878	0.51	TMEM127	transmembrane protein 127	3544	0.17
chr14_93119065_93119528	0.51	RIN3	Ras and Rab interactor 3	450	0.88
chrX_118819066_118819466	0.50	SEPT6	septin 6	7526	0.18
chr2_202098499_202098878	0.50	CASP8	caspase 8, apoptosis-related cysteine peptidase	459	0.82
chr22_18258862_18259013	0.50	BID	BH3 interacting domain death agonist	1506	0.39
chr20_30651395_30651546	0.49	HCK	hemopoietic cell kinase	11406	0.12
chr9_117145878_117146140	0.47	AKNA	AT-hook transcription factor	4234	0.24
chr8_142248690_142248841	0.47	SLC45A4	solute carrier family 45, member 4	8318	0.15
chr10_26770074_26770395	0.47	ENSG00000199733	.	28284	0.21
chr19_14551433_14551660	0.46	PKN1	protein kinase N1	474	0.7
chr2_175497594_175497986	0.46	WIPF1	WAS/WASL interacting protein family, member 1	1517	0.45
chr2_99080716_99081105	0.46	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	19497	0.22
chr2_198171190_198171625	0.46	ANKRD44	ankyrin repeat domain 44	4104	0.18
chr2_240162672_240162823	0.45	HDAC4	histone deacetylase 4	49995	0.11
chr20_4794500_4794911	0.45	RASSF2	Ras association (RalGDS/AF-6) domain family member 2	1064	0.55
chr14_93118654_93119048	0.44	RIN3	Ras and Rab interactor 3	5	0.99
chr16_30484007_30484505	0.44	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	184	0.81
chr10_119590274_119590549	0.44	RP11-354M20.3		186587	0.03
chr8_133772203_133772517	0.44	TMEM71	transmembrane protein 71	434	0.83
chr9_273119_273416	0.43	DOCK8	dedicator of cytokinesis 8	197	0.59
chr11_63656035_63656583	0.42	MARK2	MAP/microtubule affinity-regulating kinase 2	141	0.94
chr2_68964300_68964451	0.41	ARHGAP25	Rho GTPase activating protein 25	2361	0.38
chr9_117690832_117691467	0.41	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	1548	0.52
chr8_37754904_37755445	0.41	RAB11FIP1	RAB11 family interacting protein 1 (class I)	1798	0.27
chr9_128586563_128586792	0.41	PBX3	pre-B-cell leukemia homeobox 3	40873	0.21
chr8_134085908_134086059	0.41	SLA	Src-like-adaptor	13380	0.24
chr10_11206019_11206557	0.41	CELF2	CUGBP, Elav-like family member 2	705	0.72
chr1_45189703_45189968	0.41	ENSG00000199377	.	2261	0.15
chr16_28996496_28996848	0.41	LAT	linker for activation of T cells	11	0.94
chr6_42014486_42014637	0.40	CCND3	cyclin D3	1863	0.28
chr6_25036389_25036540	0.40	ENSG00000244618	.	4954	0.19
chr8_27185487_27185714	0.39	PTK2B	protein tyrosine kinase 2 beta	1260	0.49
chr3_33061158_33061309	0.39	CCR4	chemokine (C-C motif) receptor 4	68167	0.09
chr19_42057824_42058331	0.39	CEACAM21	carcinoembryonic antigen-related cell adhesion molecule 21	2191	0.27
chr7_72648551_72648702	0.38	NCF1B	neutrophil cytosolic factor 1B pseudogene	13945	0.16
chr21_39644113_39644319	0.38	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	1	0.99
chr13_30950425_30950835	0.37	KATNAL1	katanin p60 subunit A-like 1	69009	0.11
chr1_226830744_226831144	0.37	ITPKB-IT1	ITPKB intronic transcript 1 (non-protein coding)	16427	0.2
chr10_30316643_30316960	0.37	KIAA1462	KIAA1462	31652	0.24
chr2_158300794_158300945	0.37	CYTIP	cytohesin 1 interacting protein	215	0.94
chr8_125576429_125576668	0.37	MTSS1	metastasis suppressor 1	1420	0.36
chr17_80817564_80818630	0.37	TBCD	tubulin folding cofactor D	173	0.94
chr10_22622036_22622322	0.37	BMI1	BMI1 polycomb ring finger oncogene	6731	0.15
chr3_41159090_41159342	0.37	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	77112	0.12
chr6_16704232_16705187	0.36	RP1-151F17.1		56660	0.15
chr9_134145569_134145886	0.36	FAM78A	family with sequence similarity 78, member A	153	0.95
chr19_17202718_17202884	0.36	CTD-2528A14.5		7316	0.12
chr2_233925739_233925978	0.36	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	669	0.7
chr1_231748956_231749347	0.36	LINC00582	long intergenic non-protein coding RNA 582	1315	0.46
chr16_29756930_29757303	0.35	C16orf54	chromosome 16 open reading frame 54	211	0.73
chr17_33568871_33569147	0.35	RP11-799D4.4		973	0.36
chr8_21917643_21917901	0.35	DMTN	dematin actin binding protein	1038	0.39
chr14_105530971_105531214	0.35	GPR132	G protein-coupled receptor 132	675	0.7
chr19_16254556_16255035	0.35	HSH2D	hematopoietic SH2 domain containing	249	0.88
chr19_4089284_4089443	0.35	MAP2K2	mitogen-activated protein kinase kinase 2	11682	0.11
chr7_150212658_150212835	0.35	GIMAP7	GTPase, IMAP family member 7	828	0.63
chr1_161037877_161038104	0.35	ARHGAP30	Rho GTPase activating protein 30	1466	0.19
chr17_4389201_4389708	0.34	RP13-580F15.2		194	0.92
chr6_24920065_24920216	0.34	FAM65B	family with sequence similarity 65, member B	8945	0.23
chr5_176935395_176936034	0.34	DOK3	docking protein 3	1113	0.32
chr6_35268574_35268725	0.34	DEF6	differentially expressed in FDCP 6 homolog (mouse)	3020	0.24
chr17_56410108_56410593	0.34	MIR142	microRNA 142	481	0.66
chr20_47914108_47914286	0.34	ENSG00000212304	.	16977	0.12
chr3_141218227_141218432	0.34	RASA2	RAS p21 protein activator 2	12438	0.21
chr15_40475830_40476133	0.34	BUB1B	BUB1 mitotic checkpoint serine/threonine kinase B	22713	0.12
chr1_109188164_109188315	0.34	HENMT1	HEN1 methyltransferase homolog 1 (Arabidopsis)	15438	0.19
chr6_138188643_138189747	0.34	RP11-356I2.4		175	0.8
chr14_91698668_91698819	0.34	CTD-2547L24.3	HCG1816139; Uncharacterized protein	10360	0.16
chr19_3188765_3188950	0.34	NCLN	nicalin	2923	0.17
chr14_100532787_100533367	0.34	EVL	Enah/Vasp-like	303	0.88
chr9_117149358_117150269	0.34	AKNA	AT-hook transcription factor	430	0.85
chr17_72459271_72459541	0.34	CD300A	CD300a molecule	3149	0.19
chr10_30818638_30818892	0.34	ENSG00000239744	.	26068	0.21
chr13_48729935_48730086	0.33	MED4	mediator complex subunit 4	60743	0.11
chr1_26872331_26872899	0.33	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	272	0.88
chr10_82247793_82248042	0.33	TSPAN14	tetraspanin 14	28859	0.16
chr2_240188602_240189192	0.33	ENSG00000265215	.	38260	0.14
chr11_117856643_117857627	0.33	IL10RA	interleukin 10 receptor, alpha	26	0.98
chr10_98416450_98416602	0.33	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	12842	0.2
chr17_72733506_72734386	0.32	RAB37	RAB37, member RAS oncogene family	575	0.59
chr20_57266602_57266883	0.32	NPEPL1	aminopeptidase-like 1	927	0.53
chr12_25205549_25206037	0.32	LRMP	lymphoid-restricted membrane protein	119	0.97
chr10_129846333_129846652	0.32	PTPRE	protein tyrosine phosphatase, receptor type, E	658	0.81
chr2_10522774_10523051	0.32	HPCAL1	hippocalcin-like 1	37235	0.15
chr10_121297814_121297965	0.32	RGS10	regulator of G-protein signaling 10	1844	0.41
chr12_7061251_7061427	0.32	PTPN6	protein tyrosine phosphatase, non-receptor type 6	801	0.31
chr1_26644827_26645344	0.32	UBXN11	UBX domain protein 11	231	0.76
chr5_39185986_39186142	0.32	FYB	FYN binding protein	17065	0.25
chr11_72449633_72449911	0.31	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	11599	0.12
chr15_75078612_75078763	0.31	CSK	c-src tyrosine kinase	2198	0.18
chr19_1069559_1069710	0.31	HMHA1	histocompatibility (minor) HA-1	1586	0.2
chr14_22959669_22959820	0.31	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	3573	0.13
chr6_131894379_131894530	0.31	ARG1	arginase 1	89	0.97
chr17_29814991_29815971	0.30	RAB11FIP4	RAB11 family interacting protein 4 (class II)	355	0.83
chr9_139924646_139924964	0.30	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2	2065	0.1
chr19_2892956_2893107	0.30	ZNF57	zinc finger protein 57	7865	0.11
chr11_128595318_128595476	0.30	SENCR	smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA	29479	0.16
chr20_19285668_19285819	0.30	RP5-1027G4.3		20503	0.2
chr9_95727852_95728104	0.30	FGD3	FYVE, RhoGEF and PH domain containing 3	1735	0.41
chr9_36151556_36151950	0.30	GLIPR2	GLI pathogenesis-related 2	15011	0.17
chr16_88771466_88772351	0.30	RNF166	ring finger protein 166	762	0.31
chr14_22919067_22919218	0.30	TRDD3	T cell receptor delta diversity 3	1037	0.37
chr19_15574418_15574723	0.30	RASAL3	RAS protein activator like 3	812	0.5
chr11_65409143_65409294	0.29	SIPA1	signal-induced proliferation-associated 1	919	0.33
chr11_74986437_74986718	0.29	ARRB1	arrestin, beta 1	3166	0.18
chr7_150415780_150415950	0.29	GIMAP1	GTPase, IMAP family member 1	2220	0.26
chr17_4402676_4403013	0.29	AC118754.4		125	0.88
chr6_41167766_41167943	0.29	TREML2	triggering receptor expressed on myeloid cells-like 2	1078	0.4
chr16_30104448_30104599	0.29	TBX6	T-box 6	1315	0.2
chr9_130540814_130540998	0.29	SH2D3C	SH2 domain containing 3C	114	0.92
chr17_43487096_43487739	0.29	ARHGAP27	Rho GTPase activating protein 27	335	0.82
chr4_6912691_6912996	0.28	TBC1D14	TBC1 domain family, member 14	868	0.61
chr6_16707242_16707393	0.28	RP1-151F17.1		54052	0.15
chr17_262343_262585	0.28	AC108004.3		1350	0.32
chr3_111261315_111261845	0.28	CD96	CD96 molecule	583	0.82
chr19_17516551_17516849	0.28	MVB12A	multivesicular body subunit 12A	150	0.6
chr1_198648918_198649184	0.28	RP11-553K8.5		12861	0.25
chr2_60784499_60784860	0.28	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	3977	0.29
chr13_31309749_31309959	0.28	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	209	0.96
chr17_33640471_33640814	0.28	SLFN11	schlafen family member 11	39508	0.12
chr5_40849557_40849708	0.28	CARD6	caspase recruitment domain family, member 6	8222	0.15
chrX_129225529_129225680	0.28	ELF4	E74-like factor 4 (ets domain transcription factor)	18732	0.19
chr22_19349038_19349189	0.28	ENSG00000244296	.	4176	0.19
chr12_94640073_94640224	0.28	PLXNC1	plexin C1	8146	0.19
chr1_225655628_225655947	0.28	RP11-496N12.6		2742	0.3
chr10_73512307_73512458	0.28	C10orf54	chromosome 10 open reading frame 54	5005	0.22
chr8_27183780_27184189	0.27	PTK2B	protein tyrosine kinase 2 beta	356	0.89
chr21_37538870_37539021	0.27	DOPEY2	dopey family member 2	2112	0.23
chr7_50345819_50346403	0.27	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1733	0.5
chr7_37382547_37382746	0.27	ELMO1	engulfment and cell motility 1	137	0.97
chr7_73624408_73624729	0.27	LAT2	linker for activation of T cells family, member 2	215	0.92
chr16_3116517_3116777	0.27	IL32	interleukin 32	834	0.3
chr2_63287244_63287598	0.27	OTX1	orthodenticle homeobox 1	9484	0.23
chr5_131756238_131756389	0.27	AC116366.5		5833	0.14
chr20_57738915_57739179	0.27	ZNF831	zinc finger protein 831	27028	0.21
chr2_101197581_101197746	0.27	ENSG00000238328	.	3732	0.2
chr7_99954721_99954872	0.27	PILRB	paired immunoglobin-like type 2 receptor beta	207	0.86
chr11_1872722_1872911	0.27	LSP1	lymphocyte-specific protein 1	1384	0.25
chr10_73514142_73514368	0.27	C10orf54	chromosome 10 open reading frame 54	3132	0.25
chr12_4377755_4378334	0.27	CCND2	cyclin D2	4894	0.19
chr10_75625845_75625996	0.27	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma	5308	0.13
chr12_51713121_51713481	0.27	BIN2	bridging integrator 2	4598	0.18
chr6_35270264_35270539	0.26	DEF6	differentially expressed in FDCP 6 homolog (mouse)	4772	0.2
chr16_89428306_89428472	0.26	ANKRD11	ankyrin repeat domain 11	32995	0.1
chr7_50415328_50415483	0.26	IKZF1	IKAROS family zinc finger 1 (Ikaros)	48160	0.16
chr1_209943452_209943666	0.26	TRAF3IP3	TRAF3 interacting protein 3	1599	0.29
chr22_39152724_39153020	0.26	SUN2	Sad1 and UNC84 domain containing 2	867	0.37
chr14_23385013_23385164	0.26	RBM23	RNA binding motif protein 23	1677	0.16
chr1_111173785_111173949	0.26	KCNA2	potassium voltage-gated channel, shaker-related subfamily, member 2	229	0.93
chr12_739807_740337	0.26	RP11-218M22.1		15	0.97
chr2_70203509_70203660	0.26	PCBP1-AS1	PCBP1 antisense RNA 1	11678	0.14
chr13_41557045_41557196	0.26	ELF1	E74-like factor 1 (ets domain transcription factor)	702	0.71
chr17_80063977_80064793	0.26	CCDC57	coiled-coil domain containing 57	4659	0.1
chr19_8641491_8641716	0.26	MYO1F	myosin IF	719	0.54
chr3_196417091_196417380	0.26	ENSG00000201441	.	18600	0.11
chr11_6766181_6766335	0.26	GVINP1	GTPase, very large interferon inducible pseudogene 1	23147	0.11
chrX_124337019_124337170	0.26	ENSG00000263886	.	84531	0.11
chr6_35266459_35266895	0.25	DEF6	differentially expressed in FDCP 6 homolog (mouse)	1048	0.51
chr3_107843459_107843610	0.25	CD47	CD47 molecule	33662	0.22
chr14_93570056_93570236	0.25	ITPK1	inositol-tetrakisphosphate 1-kinase	11471	0.19
chr1_9713633_9713784	0.25	C1orf200	chromosome 1 open reading frame 200	936	0.49
chr12_132469658_132469809	0.25	ENSG00000271905	.	16587	0.15
chr8_48421782_48421933	0.25	RP11-697N18.4		18102	0.25
chr19_16704917_16705068	0.25	CTD-3222D19.5		6196	0.09
chr1_157789533_157789809	0.25	FCRL1	Fc receptor-like 1	179	0.95
chr16_28174772_28174923	0.25	XPO6	exportin 6	6375	0.19
chr22_39337620_39337940	0.25	APOBEC3A	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A	10976	0.14
chr6_143228096_143228637	0.25	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	37972	0.2
chr18_74766190_74766781	0.25	MBP	myelin basic protein	36751	0.2
chr1_95296828_95296979	0.25	SLC44A3	solute carrier family 44, member 3	10697	0.21
chr2_136890030_136890181	0.25	CXCR4	chemokine (C-X-C motif) receptor 4	14370	0.28
chr22_24016112_24016263	0.24	RGL4	ral guanine nucleotide dissociation stimulator-like 4	14142	0.12
chr10_98479597_98479748	0.24	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	599	0.77
chr17_7239932_7240900	0.24	ACAP1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	507	0.51
chr2_169924168_169924319	0.24	DHRS9	dehydrogenase/reductase (SDR family) member 9	656	0.74
chr5_141062081_141062481	0.24	ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	493	0.75
chr3_151915094_151915557	0.24	MBNL1	muscleblind-like splicing regulator 1	70504	0.11
chr7_143532753_143532920	0.24	RP11-61L23.2		468	0.82

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.4	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.4	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.4	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.3	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.4	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.4	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.1	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.1	0.4	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.2	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.6	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.2	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.2	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.1	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.1	0.4	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.4	GO:0046643	regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1	0.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.2	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.1	0.2	GO:0006154	adenosine catabolic process(GO:0006154)
0.1	0.2	GO:0000212	meiotic spindle organization(GO:0000212)
0.1	0.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	1.2	GO:0045576	mast cell activation(GO:0045576)
0.1	0.2	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.3	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.2	GO:0000089	mitotic metaphase(GO:0000089)
0.1	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	1.4	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.7	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.2	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.2	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.2	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0052257	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:1903224	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.2	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.3	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.2	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.7	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.2	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.0	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.1	GO:0002579	positive regulation of antigen processing and presentation(GO:0002579)
0.0	0.1	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0015853	adenine transport(GO:0015853)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.2	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:1902305	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.2	GO:0002507	tolerance induction(GO:0002507)
0.0	0.3	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.0	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.1	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.2	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.2	GO:2000193	positive regulation of fatty acid transport(GO:2000193)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.2	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.4	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.0	0.2	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.0	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0	0.1	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.2	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.2	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.2	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.3	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.1	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.2	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.4	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.2	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.2	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.3	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.2	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:0048291	isotype switching to IgG isotypes(GO:0048291)
0.0	0.3	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	1.1	GO:0006968	cellular defense response(GO:0006968)
0.0	0.1	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.4	GO:0045987	positive regulation of smooth muscle contraction(GO:0045987)
0.0	0.1	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0002886	regulation of myeloid leukocyte mediated immunity(GO:0002886)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.0	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.0	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
0.0	0.0	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.0	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.2	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.2	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.0	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.3	GO:0006906	vesicle fusion(GO:0006906)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.0	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0032816	positive regulation of natural killer cell activation(GO:0032816)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.2	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.4	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.1	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.2	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.4	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0032727	interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.4	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0042026	protein refolding(GO:0042026)
0.0	0.9	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0	0.0	GO:0003181	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0	0.0	GO:2000279	negative regulation of DNA biosynthetic process(GO:2000279)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.0	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.0	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.0	GO:0002820	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:1902743	regulation of lamellipodium organization(GO:1902743)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0	0.0	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.0	GO:0090311	regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0	0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.0	GO:0072338	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0	0.0	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0098534	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.0	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.1	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.0	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.1	GO:0045634	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.0	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.2	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.1	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.7	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0001967	suckling behavior(GO:0001967)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.0	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0035725	sodium ion transmembrane transport(GO:0035725)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.0	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.1	GO:0032367	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0000018	regulation of DNA recombination(GO:0000018)
0.0	0.2	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.0	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.0	GO:1904357	negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.0	0.0	GO:0006863	purine nucleobase transport(GO:0006863)
0.0	0.0	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.0	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.4	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0015851	nucleobase transport(GO:0015851)
0.0	0.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.2	GO:1904894	positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.0	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.0	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	0.2	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	0.0	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.0	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.1	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.0	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.0	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.0	0.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.0	0.2	GO:0051607	defense response to virus(GO:0051607)
0.0	0.1	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.0	GO:0071674	mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0	0.0	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.0	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.2	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.0	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.2	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.0	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.0	GO:0016265	obsolete death(GO:0016265)
0.0	0.0	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.0	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.0	GO:0006983	ER overload response(GO:0006983)
0.0	0.0	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.0	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.0	GO:0034311	diol metabolic process(GO:0034311)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.1	GO:0001706	endoderm formation(GO:0001706)
0.0	0.1	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0	0.0	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.2	GO:1903363	negative regulation of cellular protein catabolic process(GO:1903363)
0.0	0.0	GO:0046087	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.0	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.0	GO:0006734	NADH metabolic process(GO:0006734)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.3	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.4	GO:0042629	mast cell granule(GO:0042629)
0.1	1.0	GO:0001772	immunological synapse(GO:0001772)
0.1	0.3	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.3	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0031904	endosome lumen(GO:0031904)
0.0	0.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.3	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.5	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.0	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.3	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.5	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.2	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0042588	zymogen granule(GO:0042588)
0.0	0.0	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.0	GO:0030904	retromer complex(GO:0030904)
0.0	0.0	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.0	GO:0030891	VCB complex(GO:0030891)
0.0	1.4	GO:0005769	early endosome(GO:0005769)
0.0	0.1	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.5	GO:0030496	midbody(GO:0030496)
0.0	0.2	GO:0016234	inclusion body(GO:0016234)
0.0	0.7	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.0	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0005775	vacuolar lumen(GO:0005775)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.0	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.0	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.4	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.5	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.3	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.8	GO:0005522	profilin binding(GO:0005522)
0.1	0.3	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.5	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.2	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.3	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.5	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.2	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.4	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.2	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.4	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	1.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0043495	protein anchor(GO:0043495)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.4	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:0019956	chemokine binding(GO:0019956)
0.0	0.3	GO:0017091	AU-rich element binding(GO:0017091)
0.0	1.4	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.6	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	1.7	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.3	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.3	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.3	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.3	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.0	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.5	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.5	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.2	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.5	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.3	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.0	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.0	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.0	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.0	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.2	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	2.9	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0017069	snRNA binding(GO:0017069)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.0	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.2	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.0	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.0	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0051861	glycolipid binding(GO:0051861)
0.0	0.2	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.2	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.0	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.0	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.0	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.0	GO:0005035	death receptor activity(GO:0005035)
0.0	0.0	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.3	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.2	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.9	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	2.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	3.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	0.2	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	0.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	0.5	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.9	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	1.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.8	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.7	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.5	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.6	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.5	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.0	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.3	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.0	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.3	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	1.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.3	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.5	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.6	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.5	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.0	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.3	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.4	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.0	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.1	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.1	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.0	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.5	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.2	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus

Results for NKX2-1

Z-value: 1.59

Motif logo

Transcription factors associated with NKX2-1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the NKX2-1 motif across conditions

Conditions sorted by the z-value of the NKX2-1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: