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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NKX2-5

Z-value: 1.19

Motif logo

Transcription factors associated with NKX2-5

Gene Symbol	Gene ID	Gene Info
NKX2-5 Ensembl NCBI GeneCards UniProt	ENSG00000183072.9	NKX2-5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
NKX2-5	chr5_172665102_172665253	2817	0.247023	-0.69	3.9e-02	Click!
NKX2-5	chr5_172655987_172656138	6147	0.192582	-0.68	4.3e-02	Click!
NKX2-5	chr5_172665530_172665713	3261	0.229232	-0.61	8.2e-02	Click!
NKX2-5	chr5_172665851_172666002	3566	0.220278	-0.59	9.5e-02	Click!
NKX2-5	chr5_172660279_172660430	1855	0.328624	-0.55	1.2e-01	Click!

Activity of the NKX2-5 motif across conditions

Conditions sorted by the z-value of the NKX2-5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_130540814_130540998	0.42	SH2D3C	SH2 domain containing 3C	114	0.92
chr7_45068352_45068655	0.39	CCM2	cerebral cavernous malformation 2	1232	0.4
chr9_117692323_117692779	0.37	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	146	0.98
chr2_47527627_47527778	0.36	EPCAM	epithelial cell adhesion molecule	44595	0.13
chr12_25205549_25206037	0.34	LRMP	lymphoid-restricted membrane protein	119	0.97
chr8_82044610_82044770	0.32	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	20387	0.26
chr10_94450385_94450711	0.32	HHEX	hematopoietically expressed homeobox	295	0.91
chr6_170403243_170403627	0.31	RP11-302L19.1		74306	0.11
chr12_8276580_8276775	0.31	CLEC4A	C-type lectin domain family 4, member A	169	0.93
chr2_201988932_201989093	0.30	CFLAR	CASP8 and FADD-like apoptosis regulator	1812	0.26
chrX_123097218_123097641	0.29	STAG2	stromal antigen 2	409	0.89
chr3_13057259_13057549	0.29	IQSEC1	IQ motif and Sec7 domain 1	28868	0.23
chr1_239883177_239883989	0.28	CHRM3	cholinergic receptor, muscarinic 3	740	0.59
chr3_73046974_73047125	0.27	PPP4R2	protein phosphatase 4, regulatory subunit 2	540	0.77
chr18_43785173_43785324	0.27	C18orf25	chromosome 18 open reading frame 25	31248	0.18
chr5_130588828_130589214	0.27	CDC42SE2	CDC42 small effector 2	10681	0.28
chrX_47488390_47488605	0.27	CFP	complement factor properdin	797	0.5
chr1_156932905_156933067	0.26	ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	14180	0.14
chr6_35267244_35267414	0.26	DEF6	differentially expressed in FDCP 6 homolog (mouse)	1700	0.35
chr10_30818195_30818576	0.26	ENSG00000239744	.	26448	0.21
chr20_47374917_47375068	0.26	ENSG00000251876	.	19007	0.25
chr19_7410752_7411085	0.25	CTB-133G6.1		2930	0.22
chr22_40856327_40856478	0.25	MKL1	megakaryoblastic leukemia (translocation) 1	3020	0.24
chr4_70625874_70626025	0.25	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	367	0.91
chr17_25858505_25858818	0.24	KSR1	kinase suppressor of ras 1	51286	0.12
chr17_68317182_68317333	0.24	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2	151581	0.04
chr2_158296564_158297076	0.24	CYTIP	cytohesin 1 interacting protein	894	0.5
chr20_47896296_47896853	0.24	ENSG00000222365	.	282	0.64
chr11_33912969_33913137	0.24	LMO2	LIM domain only 2 (rhombotin-like 1)	783	0.67
chr2_10522774_10523051	0.24	HPCAL1	hippocalcin-like 1	37235	0.15
chr1_160616059_160616370	0.24	SLAMF1	signaling lymphocytic activation molecule family member 1	597	0.7
chr6_154677089_154677240	0.24	IPCEF1	interaction protein for cytohesin exchange factors 1	705	0.8
chr19_39826358_39826514	0.23	GMFG	glia maturation factor, gamma	209	0.86
chr19_8643811_8643962	0.23	MYO1F	myosin IF	1425	0.27
chr11_118094529_118095128	0.23	AMICA1	adhesion molecule, interacts with CXADR antigen 1	26	0.97
chr7_38398847_38399253	0.23	AMPH	amphiphysin	103663	0.08
chrX_41418984_41419251	0.22	CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	1763	0.34
chr5_55711065_55711234	0.22	ENSG00000265665	.	41816	0.16
chr17_403226_403444	0.22	RP5-1029F21.3		3076	0.25
chr12_7899174_7899325	0.22	CLEC4C	C-type lectin domain family 4, member C	686	0.58
chr17_4389201_4389708	0.22	RP13-580F15.2		194	0.92
chr15_40397728_40397879	0.22	BMF	Bcl2 modifying factor	484	0.77
chr7_26344680_26344872	0.22	SNX10	sorting nexin 10	12102	0.23
chr1_200337487_200337638	0.22	ZNF281	zinc finger protein 281	41558	0.21
chr14_51287046_51287197	0.22	RP11-286O18.1		1477	0.27
chr11_2323777_2324127	0.22	TSPAN32	tetraspanin 32	1	0.92
chr1_65530319_65530470	0.22	ENSG00000199135	.	6203	0.2
chr12_65005336_65005825	0.22	RASSF3	Ras association (RalGDS/AF-6) domain family member 3	1287	0.31
chr6_7431512_7431663	0.21	CAGE1	cancer antigen 1	41611	0.15
chr9_33143367_33143518	0.21	B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	15245	0.15
chr12_7061464_7061615	0.21	PTPN6	protein tyrosine phosphatase, non-receptor type 6	1001	0.24
chr2_68995972_68996266	0.21	ARHGAP25	Rho GTPase activating protein 25	5814	0.26
chr19_54871270_54871421	0.21	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	1211	0.31
chr9_95821637_95821823	0.21	SUSD3	sushi domain containing 3	669	0.69
chr5_56483162_56483313	0.21	GPBP1	GC-rich promoter binding protein 1	11464	0.23
chr10_99400020_99400179	0.20	PI4K2A	phosphatidylinositol 4-kinase type 2 alpha	344	0.83
chr22_44577376_44577610	0.20	PARVG	parvin, gamma	215	0.96
chr12_8088033_8088689	0.20	SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	421	0.8
chr5_150593261_150593549	0.20	GM2A	GM2 ganglioside activator	1694	0.36
chr22_37314565_37314716	0.20	CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	3536	0.17
chr7_150549109_150549260	0.20	AOC1	amine oxidase, copper containing 1	87	0.97
chr17_40400288_40400799	0.20	RP11-358B23.5		20062	0.1
chr3_56788528_56788714	0.20	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	20974	0.24
chr3_14467300_14467558	0.20	SLC6A6	solute carrier family 6 (neurotransmitter transporter), member 6	6749	0.24
chr12_98908665_98909156	0.20	TMPO	thymopoietin	380	0.73
chr3_183271904_183272141	0.20	KLHL6	kelch-like family member 6	1455	0.38
chr17_27621853_27622004	0.20	NUFIP2	nuclear fragile X mental retardation protein interacting protein 2	792	0.62
chr12_10281805_10282201	0.20	CLEC7A	C-type lectin domain family 7, member A	678	0.6
chr22_40781301_40781548	0.20	RP5-1042K10.10		2797	0.22
chr19_55020488_55020639	0.20	LAIR2	leukocyte-associated immunoglobulin-like receptor 2	6440	0.11
chr15_58431545_58431835	0.19	ALDH1A2	aldehyde dehydrogenase 1 family, member A2	666	0.6
chr6_35266459_35266895	0.19	DEF6	differentially expressed in FDCP 6 homolog (mouse)	1048	0.51
chr10_104957109_104957260	0.19	NT5C2	5'-nucleotidase, cytosolic II	4128	0.24
chr12_29310650_29310817	0.19	FAR2	fatty acyl CoA reductase 2	8600	0.26
chr2_145266588_145266958	0.19	ZEB2	zinc finger E-box binding homeobox 2	8342	0.25
chr10_45875884_45876035	0.19	ALOX5	arachidonate 5-lipoxygenase	6284	0.26
chr8_77911562_77912296	0.19	PEX2	peroxisomal biogenesis factor 2	533	0.85
chr9_134146658_134146835	0.19	FAM78A	family with sequence similarity 78, member A	836	0.6
chr6_35417450_35417601	0.19	FANCE	Fanconi anemia, complementation group E	2613	0.25
chr6_159087638_159088028	0.19	SYTL3	synaptotagmin-like 3	3638	0.24
chr1_221914629_221915415	0.19	DUSP10	dual specificity phosphatase 10	439	0.9
chr15_81585953_81586104	0.19	IL16	interleukin 16	3226	0.26
chr11_1782323_1782682	0.19	CTSD	cathepsin D	268	0.73
chr11_124823485_124823841	0.19	CCDC15	coiled-coil domain containing 15	354	0.83
chr5_159546809_159547203	0.19	PWWP2A	PWWP domain containing 2A	576	0.75
chr11_123302284_123302464	0.19	AP000783.1	Uncharacterized protein	1316	0.51
chr1_147097435_147097586	0.19	ACP6	acid phosphatase 6, lysophosphatidic	33606	0.18
chr5_115374516_115374667	0.19	ENSG00000220996	.	4367	0.15
chr12_65003120_65003924	0.19	RP11-338E21.1		283	0.76
chr7_150148744_150149359	0.19	GIMAP8	GTPase, IMAP family member 8	1333	0.41
chr8_56888007_56888214	0.19	ENSG00000240905	.	4986	0.18
chr1_109188485_109188636	0.18	HENMT1	HEN1 methyltransferase homolog 1 (Arabidopsis)	15117	0.19
chrX_78400540_78401325	0.18	GPR174	G protein-coupled receptor 174	25537	0.27
chr6_14911157_14911373	0.18	ENSG00000242989	.	201934	0.03
chr3_196864937_196865088	0.18	DLG1	discs, large homolog 1 (Drosophila)	45493	0.15
chr6_13273500_13273733	0.18	PHACTR1	phosphatase and actin regulator 1	627	0.46
chr12_121908453_121908604	0.18	KDM2B	lysine (K)-specific demethylase 2B	38981	0.15
chr19_50393499_50393760	0.18	ENSG00000263462	.	2197	0.1
chr9_129252632_129253068	0.18	ENSG00000221768	.	40420	0.14
chr3_129024629_129025172	0.18	H1FX-AS1	H1FX antisense RNA 1	9335	0.14
chr15_75471507_75471789	0.18	C15orf39	chromosome 15 open reading frame 39	16336	0.13
chr15_92490740_92490891	0.18	SLCO3A1	solute carrier organic anion transporter family, member 3A1	93464	0.09
chr12_65078602_65078753	0.18	AC025262.1	Mesenchymal stem cell protein DSC96; Uncharacterized protein	11652	0.14
chr6_109171993_109172144	0.18	ARMC2	armadillo repeat containing 2	2168	0.41
chr15_91415940_91416206	0.18	FURIN	furin (paired basic amino acid cleaving enzyme)	35	0.95
chr7_37382547_37382746	0.18	ELMO1	engulfment and cell motility 1	137	0.97
chr10_65001858_65002081	0.18	JMJD1C	jumonji domain containing 1C	26857	0.22
chr13_30950896_30951047	0.18	KATNAL1	katanin p60 subunit A-like 1	69350	0.11
chr4_6919199_6919395	0.18	TBC1D14	TBC1 domain family, member 14	7322	0.19
chr2_202127394_202127951	0.18	CASP8	caspase 8, apoptosis-related cysteine peptidase	993	0.56
chr9_3434244_3434395	0.18	AL365202.1	Uncharacterized protein	34862	0.2
chr13_28667454_28667735	0.18	FLT3	fms-related tyrosine kinase 3	7113	0.2
chr2_109834179_109834330	0.17	ENSG00000264934	.	76210	0.1
chr22_23560792_23560973	0.17	BCR	breakpoint cluster region	35265	0.12
chr17_3866518_3867344	0.17	ATP2A3	ATPase, Ca++ transporting, ubiquitous	654	0.71
chr17_37010201_37010405	0.17	RPL23	ribosomal protein L23	207	0.81
chr18_32609618_32610414	0.17	MAPRE2	microtubule-associated protein, RP/EB family, member 2	11308	0.29
chr9_137297751_137297902	0.17	RXRA	retinoid X receptor, alpha	602	0.8
chr1_228345004_228345155	0.17	GJC2	gap junction protein, gamma 2, 47kDa	7526	0.11
chr8_39797291_39797650	0.17	IDO2	indoleamine 2,3-dioxygenase 2	4996	0.18
chr20_52551036_52551334	0.17	AC005220.3		5514	0.29
chr19_54813883_54814034	0.17	LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	4006	0.11
chr3_138505769_138505923	0.17	PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	16449	0.26
chr2_65079480_65079631	0.17	ENSG00000199964	.	18264	0.17
chr1_209931611_209931763	0.17	TRAF3IP3	TRAF3 interacting protein 3	156	0.94
chr20_46356789_46357090	0.17	CTD-2653D5.1		50294	0.14
chr14_24782112_24782441	0.17	LTB4R	leukotriene B4 receptor	241	0.77
chr19_3178230_3178381	0.17	S1PR4	sphingosine-1-phosphate receptor 4	431	0.74
chr11_65848793_65849080	0.17	PACS1	phosphofurin acidic cluster sorting protein 1	2508	0.15
chr20_61585294_61585686	0.17	SLC17A9	solute carrier family 17 (vesicular nucleotide transporter), member 9	1092	0.44
chr14_65511146_65511303	0.17	ENSG00000266531	.	182	0.93
chr1_192128557_192128890	0.17	RGS18	regulator of G-protein signaling 18	1136	0.67
chr17_10601145_10601947	0.17	ADPRM	ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent	635	0.41
chr1_40887959_40888181	0.17	SMAP2	small ArfGAP2	25563	0.12
chr2_96922700_96922878	0.17	TMEM127	transmembrane protein 127	3544	0.17
chr7_150147681_150147832	0.17	GIMAP8	GTPase, IMAP family member 8	38	0.97
chr17_2699734_2700214	0.17	RAP1GAP2	RAP1 GTPase activating protein 2	198	0.94
chr10_49893200_49893405	0.17	WDFY4	WDFY family member 4	381	0.89
chr22_37618634_37618785	0.16	SSTR3	somatostatin receptor 3	10347	0.13
chr21_36900755_36901002	0.16	ENSG00000211590	.	192135	0.03
chr3_121966467_121966618	0.16	ENSG00000252170	.	1929	0.31
chr17_7239932_7240900	0.16	ACAP1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	507	0.51
chr2_68477764_68478263	0.16	PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	267	0.87
chr13_31312260_31312411	0.16	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	2690	0.38
chr18_21597412_21597618	0.16	TTC39C	tetratricopeptide repeat domain 39C	917	0.52
chr17_56408975_56409725	0.16	MIR142	microRNA 142	519	0.63
chr19_7742927_7743078	0.16	CTD-3214H19.16		385	0.62
chrX_135863046_135863351	0.16	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	1049	0.51
chr15_81585396_81585613	0.16	IL16	interleukin 16	3750	0.25
chr6_71961145_71961296	0.16	RP11-154D6.1		33415	0.17
chr1_145438696_145439386	0.16	TXNIP	thioredoxin interacting protein	265	0.86
chr7_50355345_50355813	0.16	IKZF1	IKAROS family zinc finger 1 (Ikaros)	7261	0.3
chr17_75955874_75956555	0.16	ENSG00000238898	.	40034	0.14
chr8_38722630_38723350	0.16	RP11-723D22.3		19033	0.16
chr17_2698922_2699102	0.16	RAP1GAP2	RAP1 GTPase activating protein 2	720	0.66
chr5_169065291_169065442	0.16	DOCK2	dedicator of cytokinesis 2	1115	0.6
chr5_158636669_158637140	0.16	CTB-11I22.1		25	0.66
chr1_183576359_183576510	0.16	NCF2	neutrophil cytosolic factor 2	16423	0.16
chrX_15995633_15995784	0.16	ENSG00000200566	.	61282	0.13
chr3_10333936_10334231	0.16	GHRL	ghrelin/obestatin prepropeptide	518	0.66
chr3_47025842_47025993	0.16	CCDC12	coiled-coil domain containing 12	2445	0.26
chr5_53942336_53942860	0.16	SNX18	sorting nexin 18	129005	0.05
chr10_72115192_72115367	0.16	LRRC20	leucine rich repeat containing 20	26135	0.16
chrX_153190511_153190813	0.16	ARHGAP4	Rho GTPase activating protein 4	1036	0.32
chr17_76129129_76129291	0.16	TMC6	transmembrane channel-like 6	722	0.51
chr15_38944932_38945157	0.16	C15orf53	chromosome 15 open reading frame 53	43755	0.17
chr6_111198520_111198699	0.16	AMD1	adenosylmethionine decarboxylase 1	1831	0.3
chr4_78047968_78048119	0.16	ENSG00000201641	.	23547	0.18
chr10_11208770_11209026	0.16	CELF2	CUGBP, Elav-like family member 2	1407	0.45
chr7_28279335_28279512	0.16	JAZF1-AS1	JAZF1 antisense RNA 1	80	0.98
chr1_230285559_230285924	0.16	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	82723	0.09
chr16_10940953_10941104	0.16	TVP23A	trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)	28386	0.13
chr16_28177392_28177543	0.16	XPO6	exportin 6	3755	0.21
chr16_81832397_81832594	0.16	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	19632	0.26
chr19_49467193_49467878	0.16	FTL	ferritin, light polypeptide	1023	0.28
chr17_76417553_76417704	0.16	AC061992.1	Uncharacterized protein	4781	0.16
chr7_45018291_45018491	0.16	MYO1G	myosin IG	306	0.85
chr7_16973346_16973562	0.16	AGR3	anterior gradient 3	51843	0.16
chr6_57086535_57087071	0.16	RAB23	RAB23, member RAS oncogene family	275	0.93
chr2_238877913_238878064	0.15	UBE2F	ubiquitin-conjugating enzyme E2F (putative)	553	0.79
chr2_32817484_32817662	0.15	TTC27	tetratricopeptide repeat domain 27	35526	0.17
chr19_51642158_51642309	0.15	SIGLEC7	sialic acid binding Ig-like lectin 7	3323	0.11
chr3_128789857_128790008	0.15	ENSG00000252435	.	2207	0.2
chr10_73529749_73529999	0.15	C10orf54	chromosome 10 open reading frame 54	3381	0.24
chr22_40607337_40607488	0.15	TNRC6B	trinucleotide repeat containing 6B	33466	0.2
chr5_139035813_139035964	0.15	CXXC5	CXXC finger protein 5	3252	0.28
chr15_63483779_63483976	0.15	RAB8B	RAB8B, member RAS oncogene family	2072	0.34
chr6_110039005_110039156	0.15	FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	1371	0.51
chr1_117057481_117057845	0.15	CD58	CD58 molecule	29549	0.14
chr12_108954436_108954604	0.15	SART3	squamous cell carcinoma antigen recognized by T cells 3	415	0.76
chr1_35659030_35659365	0.15	SFPQ	splicing factor proline/glutamine-rich	448	0.79
chr15_65134689_65135063	0.15	AC069368.3	Uncharacterized protein	729	0.4
chr2_68962051_68962936	0.15	ARHGAP25	Rho GTPase activating protein 25	479	0.86
chr2_174863074_174863225	0.15	SP3	Sp3 transcription factor	32719	0.24
chr16_3306416_3306567	0.15	MEFV	Mediterranean fever	96	0.94
chr9_88965340_88965507	0.15	ZCCHC6	zinc finger, CCHC domain containing 6	2198	0.37
chr1_89736462_89736619	0.15	GBP5	guanylate binding protein 5	6	0.98
chr7_38385599_38385750	0.15	AMPH	amphiphysin	117039	0.06
chr10_11209948_11210099	0.15	CELF2	CUGBP, Elav-like family member 2	2532	0.29
chr15_40452940_40453091	0.15	BUB1B	BUB1 mitotic checkpoint serine/threonine kinase B	212	0.92

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.3	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.3	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.1	0.3	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.2	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	0.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.2	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.3	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.2	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.2	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.2	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.2	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.2	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.3	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.3	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.2	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.4	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.1	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.1	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.1	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.3	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.1	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.2	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.1	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.2	GO:0010269	response to selenium ion(GO:0010269)
0.0	0.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.1	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.2	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.3	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0	0.2	GO:0036230	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.2	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.1	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.4	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.2	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.1	GO:0050702	interleukin-1 beta secretion(GO:0050702)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.7	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.2	GO:0051642	centrosome localization(GO:0051642)
0.0	0.3	GO:0000045	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.1	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.6	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.1	GO:0035067	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.1	GO:0032328	alanine transport(GO:0032328)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.3	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.1	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0002836	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.1	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.2	GO:0033003	regulation of mast cell activation(GO:0033003)
0.0	0.1	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.1	GO:0031498	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.0	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.0	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:1903313	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.0	GO:0010822	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.0	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0032782	bile acid secretion(GO:0032782)
0.0	0.3	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:1900087	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.1	GO:0071027	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.0	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0009208	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0045357	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.1	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.0	GO:0070076	histone lysine demethylation(GO:0070076)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.1	GO:0051593	response to folic acid(GO:0051593)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.0	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.0	GO:0009147	pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0	0.1	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.0	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.3	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.0	GO:0090030	regulation of steroid hormone biosynthetic process(GO:0090030)
0.0	0.3	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.0	0.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.0	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.2	GO:0019079	viral genome replication(GO:0019079)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0021513	spinal cord dorsal/ventral patterning(GO:0021513)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.0	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.0	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.2	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.6	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.0	GO:0060406	regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0	0.1	GO:0021591	ventricular system development(GO:0021591)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.0	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.1	GO:0048070	regulation of developmental pigmentation(GO:0048070)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	0.0	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.0	GO:1903309	negative regulation of chromatin modification(GO:1903309)
0.0	0.1	GO:0045123	cellular extravasation(GO:0045123)
0.0	0.0	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.0	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.2	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0032057	negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0050812	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.0	0.1	GO:1901998	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.0	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.1	GO:0051299	centrosome separation(GO:0051299)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0006098	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0	0.4	GO:0031124	mRNA 3'-end processing(GO:0031124)
0.0	0.0	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.2	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.2	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.1	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.0	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.2	GO:0051225	spindle assembly(GO:0051225)
0.0	0.0	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.2	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0045793	positive regulation of cell size(GO:0045793)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.2	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.3	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.3	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.4	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.0	GO:1902555	endoribonuclease complex(GO:1902555)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.2	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.2	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.1	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.0	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.5	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.0	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.2	GO:0005839	proteasome core complex(GO:0005839)
0.0	1.0	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.4	GO:0031970	mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0	0.1	GO:0042588	zymogen granule(GO:0042588)
0.0	0.0	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.0	GO:0071817	MMXD complex(GO:0071817)
0.0	0.3	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.0	GO:0000407	pre-autophagosomal structure(GO:0000407)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.4	GO:0001846	opsonin binding(GO:0001846)
0.1	0.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.4	GO:0005522	profilin binding(GO:0005522)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.2	GO:0000400	four-way junction DNA binding(GO:0000400)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.2	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.2	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.2	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.3	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.2	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.3	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	1.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.0	GO:0046980	tapasin binding(GO:0046980)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.0	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.0	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.0	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.1	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.0	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.2	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.4	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.0	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.2	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.2	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.0	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.3	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.2	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.0	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.0	0.0	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.0	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.7	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.7	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
1.0	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.6	PID IFNG PATHWAY	IFN-gamma pathway
0.5	PID BCR 5PATHWAY	BCR signaling pathway
0.5	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.3	PID ARF 3PATHWAY	Arf1 pathway
0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.2	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.2	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.4	PID ATR PATHWAY	ATR signaling pathway
0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.2	PID ARF6 PATHWAY	Arf6 signaling events
0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.1	PID BARD1 PATHWAY	BARD1 signaling events
0.6	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.4	PID RHOA REG PATHWAY	Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.0	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.0	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.7	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.1	REACTOME ORC1 REMOVAL FROM CHROMATIN	Genes involved in Orc1 removal from chromatin
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.0	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.3	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	1.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.0	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.6	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.4	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.0	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.0	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.0	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling