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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for NKX2-5

Z-value: 1.19

Motif logo

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Transcription factors associated with NKX2-5

Gene Symbol Gene ID Gene Info
NKX2-5
ENSG00000183072.9 NK2 homeobox 5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_172665102_172665253NKX2-528170.247023-0.693.9e-02Click!
chr5_172655987_172656138NKX2-561470.192582-0.684.3e-02Click!
chr5_172665530_172665713NKX2-532610.229232-0.618.2e-02Click!
chr5_172665851_172666002NKX2-535660.220278-0.599.5e-02Click!
chr5_172660279_172660430NKX2-518550.328624-0.551.2e-01Click!

Activity of the NKX2-5 motif across conditions

Conditions sorted by the z-value of the NKX2-5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_130540814_130540998 0.42 SH2D3C
 SH2 domain containing 3C
 114
 0.92
chr7_45068352_45068655 0.39 CCM2
 cerebral cavernous malformation 2
 1232
 0.4
chr9_117692323_117692779 0.37 TNFSF8
 tumor necrosis factor (ligand) superfamily, member 8
 146
 0.98
chr2_47527627_47527778 0.36 EPCAM
 epithelial cell adhesion molecule
 44595
 0.13
chr12_25205549_25206037 0.34 LRMP
 lymphoid-restricted membrane protein
 119
 0.97
chr8_82044610_82044770 0.32 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 20387
 0.26
chr10_94450385_94450711 0.32 HHEX
 hematopoietically expressed homeobox
 295
 0.91
chr6_170403243_170403627 0.31 RP11-302L19.1
74306
 0.11
chr12_8276580_8276775 0.31 CLEC4A
 C-type lectin domain family 4, member A
 169
 0.93
chr2_201988932_201989093 0.30 CFLAR
 CASP8 and FADD-like apoptosis regulator
 1812
 0.26
chrX_123097218_123097641 0.29 STAG2
 stromal antigen 2
 409
 0.89
chr3_13057259_13057549 0.29 IQSEC1
 IQ motif and Sec7 domain 1
 28868
 0.23
chr1_239883177_239883989 0.28 CHRM3
 cholinergic receptor, muscarinic 3
 740
 0.59
chr3_73046974_73047125 0.27 PPP4R2
 protein phosphatase 4, regulatory subunit 2
 540
 0.77
chr18_43785173_43785324 0.27 C18orf25
 chromosome 18 open reading frame 25
 31248
 0.18
chr5_130588828_130589214 0.27 CDC42SE2
 CDC42 small effector 2
 10681
 0.28
chrX_47488390_47488605 0.27 CFP
 complement factor properdin
 797
 0.5
chr1_156932905_156933067 0.26 ARHGEF11
 Rho guanine nucleotide exchange factor (GEF) 11
 14180
 0.14
chr6_35267244_35267414 0.26 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 1700
 0.35
chr10_30818195_30818576 0.26 ENSG00000239744
 .
 26448
 0.21
chr20_47374917_47375068 0.26 ENSG00000251876
 .
 19007
 0.25
chr19_7410752_7411085 0.25 CTB-133G6.1
2930
 0.22
chr22_40856327_40856478 0.25 MKL1
 megakaryoblastic leukemia (translocation) 1
 3020
 0.24
chr4_70625874_70626025 0.25 SULT1B1
 sulfotransferase family, cytosolic, 1B, member 1
 367
 0.91
chr17_25858505_25858818 0.24 KSR1
 kinase suppressor of ras 1
 51286
 0.12
chr17_68317182_68317333 0.24 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
 151581
 0.04
chr2_158296564_158297076 0.24 CYTIP
 cytohesin 1 interacting protein
 894
 0.5
chr20_47896296_47896853 0.24 ENSG00000222365
 .
 282
 0.64
chr11_33912969_33913137 0.24 LMO2
 LIM domain only 2 (rhombotin-like 1)
 783
 0.67
chr2_10522774_10523051 0.24 HPCAL1
 hippocalcin-like 1
 37235
 0.15
chr1_160616059_160616370 0.24 SLAMF1
 signaling lymphocytic activation molecule family member 1
 597
 0.7
chr6_154677089_154677240 0.24 IPCEF1
 interaction protein for cytohesin exchange factors 1
 705
 0.8
chr19_39826358_39826514 0.23 GMFG
 glia maturation factor, gamma
 209
 0.86
chr19_8643811_8643962 0.23 MYO1F
 myosin IF
 1425
 0.27
chr11_118094529_118095128 0.23 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 26
 0.97
chr7_38398847_38399253 0.23 AMPH
 amphiphysin
 103663
 0.08
chrX_41418984_41419251 0.22 CASK
 calcium/calmodulin-dependent serine protein kinase (MAGUK family)
 1763
 0.34
chr5_55711065_55711234 0.22 ENSG00000265665
 .
 41816
 0.16
chr17_403226_403444 0.22 RP5-1029F21.3
3076
 0.25
chr12_7899174_7899325 0.22 CLEC4C
 C-type lectin domain family 4, member C
 686
 0.58
chr17_4389201_4389708 0.22 RP13-580F15.2
194
 0.92
chr15_40397728_40397879 0.22 BMF
 Bcl2 modifying factor
 484
 0.77
chr7_26344680_26344872 0.22 SNX10
 sorting nexin 10
 12102
 0.23
chr1_200337487_200337638 0.22 ZNF281
 zinc finger protein 281
 41558
 0.21
chr14_51287046_51287197 0.22 RP11-286O18.1
1477
 0.27
chr11_2323777_2324127 0.22 TSPAN32
 tetraspanin 32
 1
 0.92
chr1_65530319_65530470 0.22 ENSG00000199135
 .
 6203
 0.2
chr12_65005336_65005825 0.22 RASSF3
 Ras association (RalGDS/AF-6) domain family member 3
 1287
 0.31
chr6_7431512_7431663 0.21 CAGE1
 cancer antigen 1
 41611
 0.15
chr9_33143367_33143518 0.21 B4GALT1
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
 15245
 0.15
chr12_7061464_7061615 0.21 PTPN6
 protein tyrosine phosphatase, non-receptor type 6
 1001
 0.24
chr2_68995972_68996266 0.21 ARHGAP25
 Rho GTPase activating protein 25
 5814
 0.26
chr19_54871270_54871421 0.21 LAIR1
 leukocyte-associated immunoglobulin-like receptor 1
 1211
 0.31
chr9_95821637_95821823 0.21 SUSD3
 sushi domain containing 3
 669
 0.69
chr5_56483162_56483313 0.21 GPBP1
 GC-rich promoter binding protein 1
 11464
 0.23
chr10_99400020_99400179 0.20 PI4K2A
 phosphatidylinositol 4-kinase type 2 alpha
 344
 0.83
chr22_44577376_44577610 0.20 PARVG
 parvin, gamma
 215
 0.96
chr12_8088033_8088689 0.20 SLC2A3
 solute carrier family 2 (facilitated glucose transporter), member 3
 421
 0.8
chr5_150593261_150593549 0.20 GM2A
 GM2 ganglioside activator
 1694
 0.36
chr22_37314565_37314716 0.20 CSF2RB
 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
 3536
 0.17
chr7_150549109_150549260 0.20 AOC1
 amine oxidase, copper containing 1
 87
 0.97
chr17_40400288_40400799 0.20 RP11-358B23.5
20062
 0.1
chr3_56788528_56788714 0.20 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
 20974
 0.24
chr3_14467300_14467558 0.20 SLC6A6
 solute carrier family 6 (neurotransmitter transporter), member 6
 6749
 0.24
chr12_98908665_98909156 0.20 TMPO
 thymopoietin
 380
 0.73
chr3_183271904_183272141 0.20 KLHL6
 kelch-like family member 6
 1455
 0.38
chr17_27621853_27622004 0.20 NUFIP2
 nuclear fragile X mental retardation protein interacting protein 2
 792
 0.62
chr12_10281805_10282201 0.20 CLEC7A
 C-type lectin domain family 7, member A
 678
 0.6
chr22_40781301_40781548 0.20 RP5-1042K10.10
2797
 0.22
chr19_55020488_55020639 0.20 LAIR2
 leukocyte-associated immunoglobulin-like receptor 2
 6440
 0.11
chr15_58431545_58431835 0.19 ALDH1A2
 aldehyde dehydrogenase 1 family, member A2
 666
 0.6
chr6_35266459_35266895 0.19 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 1048
 0.51
chr10_104957109_104957260 0.19 NT5C2
 5'-nucleotidase, cytosolic II
 4128
 0.24
chr12_29310650_29310817 0.19 FAR2
 fatty acyl CoA reductase 2
 8600
 0.26
chr2_145266588_145266958 0.19 ZEB2
 zinc finger E-box binding homeobox 2
 8342
 0.25
chr10_45875884_45876035 0.19 ALOX5
 arachidonate 5-lipoxygenase
 6284
 0.26
chr8_77911562_77912296 0.19 PEX2
 peroxisomal biogenesis factor 2
 533
 0.85
chr9_134146658_134146835 0.19 FAM78A
 family with sequence similarity 78, member A
 836
 0.6
chr6_35417450_35417601 0.19 FANCE
 Fanconi anemia, complementation group E
 2613
 0.25
chr6_159087638_159088028 0.19 SYTL3
 synaptotagmin-like 3
 3638
 0.24
chr1_221914629_221915415 0.19 DUSP10
 dual specificity phosphatase 10
 439
 0.9
chr15_81585953_81586104 0.19 IL16
 interleukin 16
 3226
 0.26
chr11_1782323_1782682 0.19 CTSD
 cathepsin D
 268
 0.73
chr11_124823485_124823841 0.19 CCDC15
 coiled-coil domain containing 15
 354
 0.83
chr5_159546809_159547203 0.19 PWWP2A
 PWWP domain containing 2A
 576
 0.75
chr11_123302284_123302464 0.19 AP000783.1
 Uncharacterized protein
 1316
 0.51
chr1_147097435_147097586 0.19 ACP6
 acid phosphatase 6, lysophosphatidic
 33606
 0.18
chr5_115374516_115374667 0.19 ENSG00000220996
 .
 4367
 0.15
chr12_65003120_65003924 0.19 RP11-338E21.1
283
 0.76
chr7_150148744_150149359 0.19 GIMAP8
 GTPase, IMAP family member 8
 1333
 0.41
chr8_56888007_56888214 0.19 ENSG00000240905
 .
 4986
 0.18
chr1_109188485_109188636 0.18 HENMT1
 HEN1 methyltransferase homolog 1 (Arabidopsis)
 15117
 0.19
chrX_78400540_78401325 0.18 GPR174
 G protein-coupled receptor 174
 25537
 0.27
chr6_14911157_14911373 0.18 ENSG00000242989
 .
 201934
 0.03
chr3_196864937_196865088 0.18 DLG1
 discs, large homolog 1 (Drosophila)
 45493
 0.15
chr6_13273500_13273733 0.18 PHACTR1
 phosphatase and actin regulator 1
 627
 0.46
chr12_121908453_121908604 0.18 KDM2B
 lysine (K)-specific demethylase 2B
 38981
 0.15
chr19_50393499_50393760 0.18 ENSG00000263462
 .
 2197
 0.1
chr9_129252632_129253068 0.18 ENSG00000221768
 .
 40420
 0.14
chr3_129024629_129025172 0.18 H1FX-AS1
 H1FX antisense RNA 1
 9335
 0.14
chr15_75471507_75471789 0.18 C15orf39
 chromosome 15 open reading frame 39
 16336
 0.13
chr15_92490740_92490891 0.18 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
 93464
 0.09
chr12_65078602_65078753 0.18 AC025262.1
 Mesenchymal stem cell protein DSC96; Uncharacterized protein
 11652
 0.14
chr6_109171993_109172144 0.18 ARMC2
 armadillo repeat containing 2
 2168
 0.41
chr15_91415940_91416206 0.18 FURIN
 furin (paired basic amino acid cleaving enzyme)
 35
 0.95
chr7_37382547_37382746 0.18 ELMO1
 engulfment and cell motility 1
 137
 0.97
chr10_65001858_65002081 0.18 JMJD1C
 jumonji domain containing 1C
 26857
 0.22
chr13_30950896_30951047 0.18 KATNAL1
 katanin p60 subunit A-like 1
 69350
 0.11
chr4_6919199_6919395 0.18 TBC1D14
 TBC1 domain family, member 14
 7322
 0.19
chr2_202127394_202127951 0.18 CASP8
 caspase 8, apoptosis-related cysteine peptidase
 993
 0.56
chr9_3434244_3434395 0.18 AL365202.1
 Uncharacterized protein
 34862
 0.2
chr13_28667454_28667735 0.18 FLT3
 fms-related tyrosine kinase 3
 7113
 0.2
chr2_109834179_109834330 0.17 ENSG00000264934
 .
 76210
 0.1
chr22_23560792_23560973 0.17 BCR
 breakpoint cluster region
 35265
 0.12
chr17_3866518_3867344 0.17 ATP2A3
 ATPase, Ca++ transporting, ubiquitous
 654
 0.71
chr17_37010201_37010405 0.17 RPL23
 ribosomal protein L23
 207
 0.81
chr18_32609618_32610414 0.17 MAPRE2
 microtubule-associated protein, RP/EB family, member 2
 11308
 0.29
chr9_137297751_137297902 0.17 RXRA
 retinoid X receptor, alpha
 602
 0.8
chr1_228345004_228345155 0.17 GJC2
 gap junction protein, gamma 2, 47kDa
 7526
 0.11
chr8_39797291_39797650 0.17 IDO2
 indoleamine 2,3-dioxygenase 2
 4996
 0.18
chr20_52551036_52551334 0.17 AC005220.3
5514
 0.29
chr19_54813883_54814034 0.17 LILRA3
 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
 4006
 0.11
chr3_138505769_138505923 0.17 PIK3CB
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
 16449
 0.26
chr2_65079480_65079631 0.17 ENSG00000199964
 .
 18264
 0.17
chr1_209931611_209931763 0.17 TRAF3IP3
 TRAF3 interacting protein 3
 156
 0.94
chr20_46356789_46357090 0.17 CTD-2653D5.1
50294
 0.14
chr14_24782112_24782441 0.17 LTB4R
 leukotriene B4 receptor
 241
 0.77
chr19_3178230_3178381 0.17 S1PR4
 sphingosine-1-phosphate receptor 4
 431
 0.74
chr11_65848793_65849080 0.17 PACS1
 phosphofurin acidic cluster sorting protein 1
 2508
 0.15
chr20_61585294_61585686 0.17 SLC17A9
 solute carrier family 17 (vesicular nucleotide transporter), member 9
 1092
 0.44
chr14_65511146_65511303 0.17 ENSG00000266531
 .
 182
 0.93
chr1_192128557_192128890 0.17 RGS18
 regulator of G-protein signaling 18
 1136
 0.67
chr17_10601145_10601947 0.17 ADPRM
 ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
 635
 0.41
chr1_40887959_40888181 0.17 SMAP2
 small ArfGAP2
 25563
 0.12
chr2_96922700_96922878 0.17 TMEM127
 transmembrane protein 127
 3544
 0.17
chr7_150147681_150147832 0.17 GIMAP8
 GTPase, IMAP family member 8
 38
 0.97
chr17_2699734_2700214 0.17 RAP1GAP2
 RAP1 GTPase activating protein 2
 198
 0.94
chr10_49893200_49893405 0.17 WDFY4
 WDFY family member 4
 381
 0.89
chr22_37618634_37618785 0.16 SSTR3
 somatostatin receptor 3
 10347
 0.13
chr21_36900755_36901002 0.16 ENSG00000211590
 .
 192135
 0.03
chr3_121966467_121966618 0.16 ENSG00000252170
 .
 1929
 0.31
chr17_7239932_7240900 0.16 ACAP1
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
 507
 0.51
chr2_68477764_68478263 0.16 PPP3R1
 protein phosphatase 3, regulatory subunit B, alpha
 267
 0.87
chr13_31312260_31312411 0.16 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
 2690
 0.38
chr18_21597412_21597618 0.16 TTC39C
 tetratricopeptide repeat domain 39C
 917
 0.52
chr17_56408975_56409725 0.16 MIR142
 microRNA 142
 519
 0.63
chr19_7742927_7743078 0.16 CTD-3214H19.16
385
 0.62
chrX_135863046_135863351 0.16 ARHGEF6
 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
 1049
 0.51
chr15_81585396_81585613 0.16 IL16
 interleukin 16
 3750
 0.25
chr6_71961145_71961296 0.16 RP11-154D6.1
33415
 0.17
chr1_145438696_145439386 0.16 TXNIP
 thioredoxin interacting protein
 265
 0.86
chr7_50355345_50355813 0.16 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 7261
 0.3
chr17_75955874_75956555 0.16 ENSG00000238898
 .
 40034
 0.14
chr8_38722630_38723350 0.16 RP11-723D22.3
19033
 0.16
chr17_2698922_2699102 0.16 RAP1GAP2
 RAP1 GTPase activating protein 2
 720
 0.66
chr5_169065291_169065442 0.16 DOCK2
 dedicator of cytokinesis 2
 1115
 0.6
chr5_158636669_158637140 0.16 CTB-11I22.1
25
 0.66
chr1_183576359_183576510 0.16 NCF2
 neutrophil cytosolic factor 2
 16423
 0.16
chrX_15995633_15995784 0.16 ENSG00000200566
 .
 61282
 0.13
chr3_10333936_10334231 0.16 GHRL
 ghrelin/obestatin prepropeptide
 518
 0.66
chr3_47025842_47025993 0.16 CCDC12
 coiled-coil domain containing 12
 2445
 0.26
chr5_53942336_53942860 0.16 SNX18
 sorting nexin 18
 129005
 0.05
chr10_72115192_72115367 0.16 LRRC20
 leucine rich repeat containing 20
 26135
 0.16
chrX_153190511_153190813 0.16 ARHGAP4
 Rho GTPase activating protein 4
 1036
 0.32
chr17_76129129_76129291 0.16 TMC6
 transmembrane channel-like 6
 722
 0.51
chr15_38944932_38945157 0.16 C15orf53
 chromosome 15 open reading frame 53
 43755
 0.17
chr6_111198520_111198699 0.16 AMD1
 adenosylmethionine decarboxylase 1
 1831
 0.3
chr4_78047968_78048119 0.16 ENSG00000201641
 .
 23547
 0.18
chr10_11208770_11209026 0.16 CELF2
 CUGBP, Elav-like family member 2
 1407
 0.45
chr7_28279335_28279512 0.16 JAZF1-AS1
 JAZF1 antisense RNA 1
 80
 0.98
chr1_230285559_230285924 0.16 GALNT2
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
 82723
 0.09
chr16_10940953_10941104 0.16 TVP23A
 trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)
 28386
 0.13
chr16_28177392_28177543 0.16 XPO6
 exportin 6
 3755
 0.21
chr16_81832397_81832594 0.16 PLCG2
 phospholipase C, gamma 2 (phosphatidylinositol-specific)
 19632
 0.26
chr19_49467193_49467878 0.16 FTL
 ferritin, light polypeptide
 1023
 0.28
chr17_76417553_76417704 0.16 AC061992.1
 Uncharacterized protein
 4781
 0.16
chr7_45018291_45018491 0.16 MYO1G
 myosin IG
 306
 0.85
chr7_16973346_16973562 0.16 AGR3
 anterior gradient 3
 51843
 0.16
chr6_57086535_57087071 0.16 RAB23
 RAB23, member RAS oncogene family
 275
 0.93
chr2_238877913_238878064 0.15 UBE2F
 ubiquitin-conjugating enzyme E2F (putative)
 553
 0.79
chr2_32817484_32817662 0.15 TTC27
 tetratricopeptide repeat domain 27
 35526
 0.17
chr19_51642158_51642309 0.15 SIGLEC7
 sialic acid binding Ig-like lectin 7
 3323
 0.11
chr3_128789857_128790008 0.15 ENSG00000252435
 .
 2207
 0.2
chr10_73529749_73529999 0.15 C10orf54
 chromosome 10 open reading frame 54
 3381
 0.24
chr22_40607337_40607488 0.15 TNRC6B
 trinucleotide repeat containing 6B
 33466
 0.2
chr5_139035813_139035964 0.15 CXXC5
 CXXC finger protein 5
 3252
 0.28
chr15_63483779_63483976 0.15 RAB8B
 RAB8B, member RAS oncogene family
 2072
 0.34
chr6_110039005_110039156 0.15 FIG4
 FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
 1371
 0.51
chr1_117057481_117057845 0.15 CD58
 CD58 molecule
 29549
 0.14
chr12_108954436_108954604 0.15 SART3
 squamous cell carcinoma antigen recognized by T cells 3
 415
 0.76
chr1_35659030_35659365 0.15 SFPQ
 splicing factor proline/glutamine-rich
 448
 0.79
chr15_65134689_65135063 0.15 AC069368.3
 Uncharacterized protein
 729
 0.4
chr2_68962051_68962936 0.15 ARHGAP25
 Rho GTPase activating protein 25
 479
 0.86
chr2_174863074_174863225 0.15 SP3
 Sp3 transcription factor
 32719
 0.24
chr16_3306416_3306567 0.15 MEFV
 Mediterranean fever
 96
 0.94
chr9_88965340_88965507 0.15 ZCCHC6
 zinc finger, CCHC domain containing 6
 2198
 0.37
chr1_89736462_89736619 0.15 GBP5
 guanylate binding protein 5
 6
 0.98
chr7_38385599_38385750 0.15 AMPH
 amphiphysin
 117039
 0.06
chr10_11209948_11210099 0.15 CELF2
 CUGBP, Elav-like family member 2
 2532
 0.29
chr15_40452940_40453091 0.15 BUB1B
 BUB1 mitotic checkpoint serine/threonine kinase B
 212
 0.92

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.3 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.3 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.1 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.2 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.2 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.2 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.2 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.4 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0019042 viral latency(GO:0019042)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.3 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.2 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.4 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.2 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0050702 interleukin-1 beta secretion(GO:0050702)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.7 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.2 GO:0051642 centrosome localization(GO:0051642)
0.0 0.3 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.6 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0035067 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.1 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0002836 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0 0.1 GO:0051383 kinetochore organization(GO:0051383)
0.0 0.2 GO:0033003 regulation of mast cell activation(GO:0033003)
0.0 0.1 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.1 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:1903313 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:0010822 positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.0 GO:0019322 pentose biosynthetic process(GO:0019322)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.3 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.1 GO:0071027 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.0 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0009208 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0070076 histone lysine demethylation(GO:0070076)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.1 GO:0051593 response to folic acid(GO:0051593)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0 0.0 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0002467 germinal center formation(GO:0002467)
0.0 0.1 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.0 GO:0009147 pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0 0.1 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0090030 regulation of steroid hormone biosynthetic process(GO:0090030)
0.0 0.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.0 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.2 GO:0019079 viral genome replication(GO:0019079)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.0 GO:0032048 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.0 GO:0060406 regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0021591 ventricular system development(GO:0021591)
0.0 0.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.0 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0048070 regulation of developmental pigmentation(GO:0048070)
0.0 0.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.0 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:1903309 negative regulation of chromatin modification(GO:1903309)
0.0 0.1 GO:0045123 cellular extravasation(GO:0045123)
0.0 0.0 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.0 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0032057 negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.0 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.0 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.1 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.1 GO:1901998 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0051299 centrosome separation(GO:0051299)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.4 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.0 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.0 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0045793 positive regulation of cell size(GO:0045793)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.2 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.0 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.0 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.0 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.5 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0031082 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0042588 zymogen granule(GO:0042588)
0.0 0.0 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.0 GO:0071817 MMXD complex(GO:0071817)
0.0 0.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.0 GO:0000407 pre-autophagosomal structure(GO:0000407)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.4 GO:0001846 opsonin binding(GO:0001846)
0.1 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.0 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.0 GO:0046980 tapasin binding(GO:0046980)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.0 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.0 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.0 0.0 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.4 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.0 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.1 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.0 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.0 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling