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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 0.31

Motif logo

Transcription factors associated with NOTO_VSX2_DLX2_DLX6_NKX6-1

Gene Symbol	Gene ID	Gene Info
NOTO Ensembl NCBI GeneCards UniProt	ENSG00000214513.3	NOTO
VSX2 Ensembl NCBI GeneCards UniProt	ENSG00000119614.2	VSX2
DLX2 Ensembl NCBI GeneCards UniProt	ENSG00000115844.6	DLX2
DLX6 Ensembl NCBI GeneCards UniProt	ENSG00000006377.9	DLX6
NKX6-1 Ensembl NCBI GeneCards UniProt	ENSG00000163623.5	NKX6-1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
DLX2	chr2_172970805_172971712	3630	0.254786	-0.76	1.8e-02	Click!
DLX2	chr2_172963527_172963843	3943	0.244525	-0.64	6.4e-02	Click!
DLX2	chr2_172970602_172970787	3066	0.273655	-0.59	9.2e-02	Click!
DLX2	chr2_172961462_172961931	5932	0.218659	-0.53	1.4e-01	Click!
DLX2	chr2_172960519_172960695	7021	0.211664	-0.52	1.5e-01	Click!
DLX6	chr7_96635533_96635717	335	0.793174	-0.51	1.6e-01	Click!
DLX6	chr7_96634475_96634654	296	0.789736	-0.47	2.0e-01	Click!
DLX6	chr7_96635226_96635397	21	0.957943	-0.41	2.7e-01	Click!
DLX6	chr7_96634662_96635012	23	0.954019	-0.38	3.2e-01	Click!
DLX6	chr7_96635926_96636202	673	0.484864	-0.38	3.2e-01	Click!
NKX6-1	chr4_85414354_85414505	3674	0.350707	-0.61	7.8e-02	Click!
NKX6-1	chr4_85419922_85420185	450	0.893788	-0.61	8.3e-02	Click!
NKX6-1	chr4_85420275_85420452	760	0.772953	-0.59	9.2e-02	Click!
NKX6-1	chr4_85419328_85419920	21	0.987510	-0.58	9.9e-02	Click!
NKX6-1	chr4_85418590_85418741	562	0.851816	-0.47	2.0e-01	Click!
NOTO	chr2_73429434_73429594	128	0.949734	-0.49	1.8e-01	Click!
NOTO	chr2_73402539_73402866	26684	0.129677	-0.38	3.1e-01	Click!
NOTO	chr2_73404796_73404997	24490	0.132908	-0.31	4.1e-01	Click!
NOTO	chr2_73429933_73430225	693	0.616065	0.30	4.3e-01	Click!
NOTO	chr2_73403004_73403567	26101	0.130556	-0.16	6.8e-01	Click!
VSX2	chr14_74718219_74718381	12125	0.152141	-0.49	1.8e-01	Click!
VSX2	chr14_74725090_74725251	18995	0.134493	-0.41	2.7e-01	Click!
VSX2	chr14_74707042_74707610	1151	0.458714	0.26	5.0e-01	Click!
VSX2	chr14_74684578_74684763	21505	0.151615	-0.26	5.1e-01	Click!
VSX2	chr14_74684411_74684562	21689	0.151271	0.22	5.6e-01	Click!

Activity of the NOTO_VSX2_DLX2_DLX6_NKX6-1 motif across conditions

Conditions sorted by the z-value of the NOTO_VSX2_DLX2_DLX6_NKX6-1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chrX_78400540_78401325	0.13	GPR174	G protein-coupled receptor 174	25537	0.27
chr6_154568354_154568864	0.10	IPCEF1	interaction protein for cytohesin exchange factors 1	53	0.99
chr7_50345819_50346403	0.08	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1733	0.5
chr5_126094279_126094440	0.06	ENSG00000252185	.	3250	0.29
chr6_159464766_159465080	0.06	TAGAP	T-cell activation RhoGTPase activating protein	1127	0.51
chr2_61111507_61111691	0.05	REL	v-rel avian reticuloendotheliosis viral oncogene homolog	2808	0.27
chr2_143887292_143887566	0.05	ARHGAP15	Rho GTPase activating protein 15	546	0.84
chr6_25041553_25042305	0.05	RP3-425P12.5		138	0.72
chr14_88471433_88472132	0.05	GPR65	G protein-coupled receptor 65	314	0.88
chr7_106507255_106507406	0.05	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	1406	0.54
chr3_151961363_151961565	0.05	MBNL1	muscleblind-like splicing regulator 1	24365	0.2
chr7_50348449_50348781	0.05	IKZF1	IKAROS family zinc finger 1 (Ikaros)	297	0.94
chr12_9912992_9913534	0.05	CD69	CD69 molecule	234	0.92
chr5_118606885_118607036	0.05	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	2511	0.28
chr13_99957828_99957979	0.05	GPR183	G protein-coupled receptor 183	1756	0.38
chr4_36245078_36245884	0.05	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	80	0.74
chr5_118606012_118606179	0.05	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	1646	0.37
chr15_75080868_75081404	0.05	ENSG00000264386	.	38	0.76
chr14_22974481_22974956	0.04	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	18547	0.09
chr1_198627689_198627922	0.04	RP11-553K8.5		8385	0.25
chr7_37011253_37011404	0.04	ELMO1	engulfment and cell motility 1	13337	0.2
chr2_193992778_193992929	0.04	TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2	932418	0.0
chr1_180387724_180387875	0.04	ENSG00000265435	.	19726	0.22
chr1_198615140_198615291	0.04	PTPRC	protein tyrosine phosphatase, receptor type, C	6923	0.25
chrX_78620994_78621299	0.04	ITM2A	integral membrane protein 2A	1710	0.55
chr10_33425652_33425891	0.04	ENSG00000263576	.	38207	0.16
chr21_32567568_32567719	0.04	TIAM1	T-cell lymphoma invasion and metastasis 1	65104	0.13
chr1_234544831_234544982	0.04	COA6	cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)	35459	0.12
chr6_26198173_26198564	0.04	HIST1H3D	histone cluster 1, H3d	890	0.22
chr2_68961577_68961872	0.04	ARHGAP25	Rho GTPase activating protein 25	189	0.96
chr3_43329409_43329595	0.04	SNRK	SNF related kinase	1424	0.43
chr1_29253817_29254129	0.04	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	12882	0.18
chrX_11780001_11780185	0.04	MSL3	male-specific lethal 3 homolog (Drosophila)	2346	0.44
chr6_159464058_159464225	0.04	TAGAP	T-cell activation RhoGTPase activating protein	1909	0.34
chr2_215664874_215665025	0.04	BARD1	BRCA1 associated RING domain 1	9448	0.21
chr10_46075820_46076565	0.04	MARCH8	membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase	13747	0.25
chr17_75456326_75456913	0.04	SEPT9	septin 9	4171	0.18
chr2_158299843_158300108	0.04	CYTIP	cytohesin 1 interacting protein	679	0.68
chr12_15112961_15113206	0.04	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	1117	0.46
chr17_29637369_29637894	0.04	EVI2B	ecotropic viral integration site 2B	3471	0.16
chr12_54891959_54892179	0.04	NCKAP1L	NCK-associated protein 1-like	499	0.73
chr1_28975271_28975442	0.04	ENSG00000270103	.	244	0.88
chr3_16883621_16883873	0.04	PLCL2	phospholipase C-like 2	42705	0.19
chr10_129861850_129862130	0.04	PTPRE	protein tyrosine phosphatase, receptor type, E	16156	0.26
chrY_2804248_2804778	0.04	ZFY	zinc finger protein, Y-linked	967	0.67
chr9_125662893_125663901	0.04	RC3H2	ring finger and CCCH-type domains 2	3008	0.16
chr5_126147731_126147991	0.04	LMNB1	lamin B1	34980	0.19
chr1_197730742_197731002	0.04	RP11-448G4.4		4423	0.25
chr7_43688967_43689164	0.04	COA1	cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)	830	0.67
chr1_112013416_112013602	0.04	C1orf162	chromosome 1 open reading frame 162	2905	0.14
chr19_42390602_42391041	0.04	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	2306	0.19
chr7_33078848_33079779	0.04	NT5C3A	5'-nucleotidase, cytosolic IIIA	1208	0.42
chr5_130882612_130883040	0.04	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	14100	0.29
chr1_100852790_100852941	0.04	ENSG00000216067	.	8534	0.21
chr3_151963607_151963763	0.04	MBNL1	muscleblind-like splicing regulator 1	22144	0.21
chr16_31271922_31272073	0.04	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	682	0.53
chr13_46745397_46745548	0.04	ENSG00000240767	.	1589	0.32
chr7_115668295_115668446	0.04	TFEC	transcription factor EC	2425	0.43
chr4_144312492_144312643	0.04	GAB1	GRB2-associated binding protein 1	96	0.98
chr12_47600587_47601314	0.04	PCED1B	PC-esterase domain containing 1B	9102	0.22
chr4_154411300_154411567	0.04	KIAA0922	KIAA0922	23932	0.22
chr2_174129320_174129481	0.04	MLK7-AS1	MLK7 antisense RNA 1	6948	0.3
chr17_10601145_10601947	0.04	ADPRM	ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent	635	0.41
chr1_24862040_24862255	0.04	ENSG00000266551	.	5943	0.18
chr11_128589269_128589524	0.04	SENCR	smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA	23478	0.17
chr17_28085648_28085799	0.04	RP11-82O19.1		2398	0.25
chr3_98253310_98253461	0.03	GPR15	G protein-coupled receptor 15	2642	0.21
chr10_26771389_26771611	0.03	ENSG00000199733	.	27018	0.21
chr16_50776896_50777610	0.03	RP11-327F22.1		527	0.39
chr15_55547653_55548107	0.03	RAB27A	RAB27A, member RAS oncogene family	6647	0.22
chr21_15917916_15918619	0.03	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	395	0.89
chr14_22977314_22977663	0.03	TRAJ15	T cell receptor alpha joining 15	21092	0.09
chr12_95071864_95072096	0.03	TMCC3	transmembrane and coiled-coil domain family 3	27642	0.23
chr1_150584633_150584820	0.03	ENSG00000253047	.	11591	0.1
chr16_81030456_81031156	0.03	CMC2	C-x(9)-C motif containing 2	1458	0.31
chr10_112632655_112633305	0.03	PDCD4-AS1	PDCD4 antisense RNA 1	989	0.38
chr11_128392558_128393039	0.03	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	593	0.77
chr13_41372571_41372761	0.03	SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	5372	0.18
chr12_131796680_131796831	0.03	ENSG00000212251	.	12459	0.23
chrX_129243329_129244377	0.03	ELF4	E74-like factor 4 (ets domain transcription factor)	483	0.82
chr19_6481304_6482171	0.03	DENND1C	DENN/MADD domain containing 1C	27	0.95
chr1_200987607_200987758	0.03	KIF21B	kinesin family member 21B	4854	0.21
chr18_56326442_56326593	0.03	MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	12101	0.14
chr1_200865204_200865355	0.03	C1orf106	chromosome 1 open reading frame 106	1330	0.42
chr22_31615175_31615326	0.03	ENSG00000199695	.	3589	0.13
chr12_8666250_8666401	0.03	CLEC4D	C-type lectin domain family 4, member D	189	0.93
chr3_108543496_108543820	0.03	TRAT1	T cell receptor associated transmembrane adaptor 1	2039	0.42
chr14_70111468_70111619	0.03	KIAA0247	KIAA0247	33230	0.18
chr1_206732541_206732911	0.03	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	2233	0.27
chr14_22747289_22747440	0.03	ENSG00000238634	.	136477	0.04
chr9_102849500_102849651	0.03	ERP44	endoplasmic reticulum protein 44	11747	0.18
chr13_46755198_46755455	0.03	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	1133	0.45
chr3_32996346_32996497	0.03	CCR4	chemokine (C-C motif) receptor 4	3355	0.33
chr3_69140694_69141185	0.03	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	6767	0.15
chr15_52844361_52844512	0.03	ARPP19	cAMP-regulated phosphoprotein, 19kDa	5505	0.2
chr21_32555155_32555306	0.03	TIAM1	T-cell lymphoma invasion and metastasis 1	52691	0.16
chr1_206753637_206754165	0.03	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	23408	0.13
chrX_9801459_9801610	0.03	ENSG00000206844	.	41207	0.15
chrX_13106517_13106711	0.03	FAM9C	family with sequence similarity 9, member C	43813	0.18
chr9_117721707_117721858	0.03	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	29085	0.23
chr1_39594945_39595096	0.03	ENSG00000206654	.	8305	0.17
chr12_65779210_65779361	0.03	MSRB3	methionine sulfoxide reductase B3	58630	0.15
chr2_99345755_99346000	0.03	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	834	0.68
chr5_81074467_81075538	0.03	SSBP2	single-stranded DNA binding protein 2	27930	0.25
chr1_231748956_231749347	0.03	LINC00582	long intergenic non-protein coding RNA 582	1315	0.46
chr18_57572017_57572168	0.03	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	4844	0.29
chr21_32559881_32560032	0.03	TIAM1	T-cell lymphoma invasion and metastasis 1	57417	0.15
chr17_21157480_21157631	0.03	C17orf103	chromosome 17 open reading frame 103	833	0.56
chr10_70850849_70851349	0.03	SRGN	serglycin	3225	0.25
chrX_118818753_118818904	0.03	SEPT6	septin 6	7964	0.18
chr20_1357596_1357769	0.03	RP11-314N13.3		15416	0.13
chr17_74564111_74564262	0.03	RP11-666A8.9		1688	0.17
chr14_22955963_22956254	0.03	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	63	0.95
chr1_236284065_236284436	0.03	GPR137B	G protein-coupled receptor 137B	21582	0.19
chr4_36243817_36244102	0.03	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	1602	0.35
chr7_94035982_94036133	0.03	COL1A2	collagen, type I, alpha 2	12184	0.27
chr7_37488846_37488997	0.03	ELMO1	engulfment and cell motility 1	69	0.98
chr15_44101218_44101369	0.03	HYPK	huntingtin interacting protein K	8496	0.08
chrX_35788537_35788688	0.03	MAGEB16	melanoma antigen family B, 16	27847	0.25
chr13_49065751_49065929	0.03	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	41373	0.17
chr17_75663137_75663644	0.03	SEPT9	septin 9	185395	0.03
chr11_104904746_104905919	0.03	CASP1	caspase 1, apoptosis-related cysteine peptidase	508	0.77
chr4_91603417_91603568	0.03	CCSER1	coiled-coil serine-rich protein 1	32830	0.25
chr10_7526759_7527322	0.03	ENSG00000207453	.	1731	0.45
chr8_27223967_27224118	0.03	PTK2B	protein tyrosine kinase 2 beta	14126	0.22
chr3_63954713_63955178	0.03	ATXN7	ataxin 7	1525	0.34
chr1_111215065_111215351	0.03	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	2447	0.28
chr12_65013240_65013416	0.03	ENSG00000207546	.	2961	0.17
chr11_20179312_20179463	0.03	DBX1	developing brain homeobox 1	2483	0.35
chr10_1779633_1779784	0.03	ADARB2	adenosine deaminase, RNA-specific, B2 (non-functional)	38	0.99
chr14_22182172_22182323	0.03	OR4E2	olfactory receptor, family 4, subfamily E, member 2	48950	0.13
chr10_134261699_134261957	0.03	C10orf91	chromosome 10 open reading frame 91	3135	0.24
chr1_90290694_90290845	0.03	LRRC8D	leucine rich repeat containing 8 family, member D	3289	0.28
chr9_184434_184636	0.03	CBWD1	COBW domain containing 1	5463	0.2
chr3_124774787_124775424	0.03	HEG1	heart development protein with EGF-like domains 1	303	0.88
chr2_136876136_136876323	0.03	CXCR4	chemokine (C-X-C motif) receptor 4	494	0.87
chr17_37933702_37934037	0.03	IKZF3	IKAROS family zinc finger 3 (Aiolos)	609	0.66
chr4_40201423_40201705	0.03	RHOH	ras homolog family member H	400	0.87
chr18_74837172_74837323	0.03	MBP	myelin basic protein	2421	0.42
chr14_90187580_90187856	0.03	ENSG00000200312	.	8863	0.23
chr1_206749362_206749620	0.03	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	18998	0.14
chr9_92032170_92032321	0.03	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	1503	0.49
chr17_56736328_56736479	0.03	ENSG00000202077	.	263	0.86
chr2_64369947_64371114	0.03	AC074289.1		157	0.93
chr2_197032053_197032740	0.03	STK17B	serine/threonine kinase 17b	3328	0.25
chr2_175458036_175458370	0.03	WIPF1	WAS/WASL interacting protein family, member 1	4290	0.21
chr9_70851276_70851465	0.03	CBWD3	COBW domain containing 3	5027	0.19
chr3_195962656_195962807	0.03	SLC51A	solute carrier family 51, alpha subunit	5855	0.13
chr10_30745504_30745655	0.03	MAP3K8	mitogen-activated protein kinase kinase kinase 8	17828	0.21
chr6_36008402_36008553	0.03	MAPK14	mitogen-activated protein kinase 14	11611	0.19
chr1_198652510_198652661	0.03	RP11-553K8.5		16395	0.24
chr5_150593261_150593549	0.03	GM2A	GM2 ganglioside activator	1694	0.36
chr8_82022711_82022967	0.03	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	1464	0.56
chr10_6626003_6626633	0.03	PRKCQ	protein kinase C, theta	4055	0.36
chr15_69074948_69075145	0.03	ENSG00000265195	.	19218	0.22
chrY_1551045_1551310	0.03	NA	NA	> 10⁶	NA
chr5_74615521_74615672	0.03	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	16558	0.19
chr7_17039488_17039788	0.03	AGR3	anterior gradient 3	118027	0.06
chr19_48832910_48833240	0.03	EMP3	epithelial membrane protein 3	4210	0.13
chr9_70495582_70495733	0.03	CBWD5	COBW domain containing 5	5411	0.29
chr1_66806017_66806168	0.03	PDE4B	phosphodiesterase 4B, cAMP-specific	8220	0.31
chr8_134086469_134086645	0.03	SLA	Src-like-adaptor	13954	0.23
chr9_80524074_80524374	0.03	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	86309	0.1
chr17_18204377_18204528	0.03	TOP3A	topoisomerase (DNA) III alpha	1531	0.27
chr14_75885513_75886422	0.03	RP11-293M10.6		8426	0.2
chr4_26269987_26270138	0.03	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	4167	0.36
chr9_69267993_69268163	0.03	CBWD6	COBW domain containing 6	5485	0.22
chr17_75450125_75450790	0.03	SEPT9	septin 9	295	0.88
chr6_167526422_167526606	0.03	CCR6	chemokine (C-C motif) receptor 6	1219	0.48
chr3_128899189_128899802	0.03	CNBP	CCHC-type zinc finger, nucleic acid binding protein	3247	0.18
chr3_107697576_107697727	0.03	CD47	CD47 molecule	79557	0.11
chr13_31312055_31312206	0.03	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	2485	0.4
chr1_21349011_21349508	0.03	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	28136	0.19
chr3_47182364_47182515	0.03	SETD2	SET domain containing 2	22627	0.16
chr18_21572812_21573447	0.02	TTC39C	tetratricopeptide repeat domain 39C	392	0.85
chr4_90226799_90226950	0.02	GPRIN3	GPRIN family member 3	2287	0.45
chr3_135909805_135909956	0.02	MSL2	male-specific lethal 2 homolog (Drosophila)	3516	0.32
chr4_38623548_38623699	0.02	RP11-617D20.1		2573	0.31
chr11_75063727_75063930	0.02	ARRB1	arrestin, beta 1	955	0.48
chr4_25865391_25865542	0.02	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)	84	0.98
chr22_18260542_18260943	0.02	BID	BH3 interacting domain death agonist	3311	0.23
chr15_43531850_43532099	0.02	ENSG00000202211	.	7904	0.13
chr8_8203302_8203453	0.02	SGK223	Tyrosine-protein kinase SgK223	35880	0.18
chr2_197133486_197133637	0.02	AC020571.3		8404	0.2
chr12_90537525_90537676	0.02	ENSG00000252823	.	389764	0.01
chr9_79265748_79266757	0.02	PRUNE2	prune homolog 2 (Drosophila)	1213	0.53
chr10_54463336_54463751	0.02	RP11-556E13.1		51626	0.16
chr6_20174159_20174424	0.02	RP11-239H6.2		38027	0.18
chr14_91863541_91863979	0.02	CCDC88C	coiled-coil domain containing 88C	19930	0.21
chr14_75990505_75990656	0.02	BATF	basic leucine zipper transcription factor, ATF-like	1677	0.38
chr6_170597990_170598273	0.02	DLL1	delta-like 1 (Drosophila)	1430	0.33
chr10_73847731_73848399	0.02	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	21	0.98
chr1_158802859_158803010	0.02	MNDA	myeloid cell nuclear differentiation antigen	1827	0.35
chr11_104940824_104940975	0.02	CARD16	caspase recruitment domain family, member 16	24796	0.15
chr4_106070591_106071096	0.02	TET2	tet methylcytosine dioxygenase 2	2229	0.34
chr8_66843424_66843611	0.02	PDE7A	phosphodiesterase 7A	89330	0.09
chrX_1600809_1601304	0.02	ASMTL	acetylserotonin O-methyltransferase-like	28401	0.16
chr17_29644876_29645027	0.02	CTD-2370N5.3		707	0.55
chr11_82882204_82882391	0.02	PCF11	PCF11 cleavage and polyadenylation factor subunit	4	0.97
chr2_175498105_175498391	0.02	WIPF1	WAS/WASL interacting protein family, member 1	1059	0.58

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NOTO_VSX2_DLX2_DLX6_NKX6-1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	GO:0010447	response to acidic pH(GO:0010447)
0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	GO:0030011	maintenance of cell polarity(GO:0030011)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)