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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 0.31

Motif logo

Transcription factors associated with NOTO_VSX2_DLX2_DLX6_NKX6-1

Gene Symbol	Gene ID	Gene Info
NOTO Ensembl NCBI GeneCards UniProt	ENSG00000214513.3	notochord homeobox
VSX2 Ensembl NCBI GeneCards UniProt	ENSG00000119614.2	visual system homeobox 2
DLX2 Ensembl NCBI GeneCards UniProt	ENSG00000115844.6	distal-less homeobox 2
DLX6 Ensembl NCBI GeneCards UniProt	ENSG00000006377.9	distal-less homeobox 6
NKX6-1 Ensembl NCBI GeneCards UniProt	ENSG00000163623.5	NK6 homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_172970805_172971712	DLX2	3630	0.254786	-0.76	1.8e-02	Click!
chr2_172963527_172963843	DLX2	3943	0.244525	-0.64	6.4e-02	Click!
chr2_172970602_172970787	DLX2	3066	0.273655	-0.59	9.2e-02	Click!
chr2_172961462_172961931	DLX2	5932	0.218659	-0.53	1.4e-01	Click!
chr2_172960519_172960695	DLX2	7021	0.211664	-0.52	1.5e-01	Click!
chr7_96635533_96635717	DLX6	335	0.793174	-0.51	1.6e-01	Click!
chr7_96634475_96634654	DLX6	296	0.789736	-0.47	2.0e-01	Click!
chr7_96635226_96635397	DLX6	21	0.957943	-0.41	2.7e-01	Click!
chr7_96634662_96635012	DLX6	23	0.954019	-0.38	3.2e-01	Click!
chr7_96635926_96636202	DLX6	673	0.484864	-0.38	3.2e-01	Click!
chr4_85414354_85414505	NKX6-1	3674	0.350707	-0.61	7.8e-02	Click!
chr4_85419922_85420185	NKX6-1	450	0.893788	-0.61	8.3e-02	Click!
chr4_85420275_85420452	NKX6-1	760	0.772953	-0.59	9.2e-02	Click!
chr4_85419328_85419920	NKX6-1	21	0.987510	-0.58	9.9e-02	Click!
chr4_85418590_85418741	NKX6-1	562	0.851816	-0.47	2.0e-01	Click!
chr2_73429434_73429594	NOTO	128	0.949734	-0.49	1.8e-01	Click!
chr2_73402539_73402866	NOTO	26684	0.129677	-0.38	3.1e-01	Click!
chr2_73404796_73404997	NOTO	24490	0.132908	-0.31	4.1e-01	Click!
chr2_73429933_73430225	NOTO	693	0.616065	0.30	4.3e-01	Click!
chr2_73403004_73403567	NOTO	26101	0.130556	-0.16	6.8e-01	Click!
chr14_74718219_74718381	VSX2	12125	0.152141	-0.49	1.8e-01	Click!
chr14_74725090_74725251	VSX2	18995	0.134493	-0.41	2.7e-01	Click!
chr14_74707042_74707610	VSX2	1151	0.458714	0.26	5.0e-01	Click!
chr14_74684578_74684763	VSX2	21505	0.151615	-0.26	5.1e-01	Click!
chr14_74684411_74684562	VSX2	21689	0.151271	0.22	5.6e-01	Click!

Activity of the NOTO_VSX2_DLX2_DLX6_NKX6-1 motif across conditions

Conditions sorted by the z-value of the NOTO_VSX2_DLX2_DLX6_NKX6-1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chrX_78400540_78401325	0.13	GPR174	G protein-coupled receptor 174	25537	0.27
chr6_154568354_154568864	0.10	IPCEF1	interaction protein for cytohesin exchange factors 1	53	0.99
chr7_50345819_50346403	0.08	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1733	0.5
chr5_126094279_126094440	0.06	ENSG00000252185	.	3250	0.29
chr6_159464766_159465080	0.06	TAGAP	T-cell activation RhoGTPase activating protein	1127	0.51
chr2_61111507_61111691	0.05	REL	v-rel avian reticuloendotheliosis viral oncogene homolog	2808	0.27
chr2_143887292_143887566	0.05	ARHGAP15	Rho GTPase activating protein 15	546	0.84
chr6_25041553_25042305	0.05	RP3-425P12.5		138	0.72
chr14_88471433_88472132	0.05	GPR65	G protein-coupled receptor 65	314	0.88
chr7_106507255_106507406	0.05	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	1406	0.54
chr3_151961363_151961565	0.05	MBNL1	muscleblind-like splicing regulator 1	24365	0.2
chr7_50348449_50348781	0.05	IKZF1	IKAROS family zinc finger 1 (Ikaros)	297	0.94
chr12_9912992_9913534	0.05	CD69	CD69 molecule	234	0.92
chr5_118606885_118607036	0.05	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	2511	0.28
chr13_99957828_99957979	0.05	GPR183	G protein-coupled receptor 183	1756	0.38
chr4_36245078_36245884	0.05	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	80	0.74
chr5_118606012_118606179	0.05	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	1646	0.37
chr15_75080868_75081404	0.05	ENSG00000264386	.	38	0.76
chr14_22974481_22974956	0.04	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	18547	0.09
chr1_198627689_198627922	0.04	RP11-553K8.5		8385	0.25
chr7_37011253_37011404	0.04	ELMO1	engulfment and cell motility 1	13337	0.2
chr2_193992778_193992929	0.04	TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2	932418	0.0
chr1_180387724_180387875	0.04	ENSG00000265435	.	19726	0.22
chr1_198615140_198615291	0.04	PTPRC	protein tyrosine phosphatase, receptor type, C	6923	0.25
chrX_78620994_78621299	0.04	ITM2A	integral membrane protein 2A	1710	0.55
chr10_33425652_33425891	0.04	ENSG00000263576	.	38207	0.16
chr21_32567568_32567719	0.04	TIAM1	T-cell lymphoma invasion and metastasis 1	65104	0.13
chr1_234544831_234544982	0.04	COA6	cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)	35459	0.12
chr6_26198173_26198564	0.04	HIST1H3D	histone cluster 1, H3d	890	0.22
chr2_68961577_68961872	0.04	ARHGAP25	Rho GTPase activating protein 25	189	0.96
chr3_43329409_43329595	0.04	SNRK	SNF related kinase	1424	0.43
chr1_29253817_29254129	0.04	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	12882	0.18
chrX_11780001_11780185	0.04	MSL3	male-specific lethal 3 homolog (Drosophila)	2346	0.44
chr6_159464058_159464225	0.04	TAGAP	T-cell activation RhoGTPase activating protein	1909	0.34
chr2_215664874_215665025	0.04	BARD1	BRCA1 associated RING domain 1	9448	0.21
chr10_46075820_46076565	0.04	MARCH8	membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase	13747	0.25
chr17_75456326_75456913	0.04	SEPT9	septin 9	4171	0.18
chr2_158299843_158300108	0.04	CYTIP	cytohesin 1 interacting protein	679	0.68
chr12_15112961_15113206	0.04	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	1117	0.46
chr17_29637369_29637894	0.04	EVI2B	ecotropic viral integration site 2B	3471	0.16
chr12_54891959_54892179	0.04	NCKAP1L	NCK-associated protein 1-like	499	0.73
chr1_28975271_28975442	0.04	ENSG00000270103	.	244	0.88
chr3_16883621_16883873	0.04	PLCL2	phospholipase C-like 2	42705	0.19
chr10_129861850_129862130	0.04	PTPRE	protein tyrosine phosphatase, receptor type, E	16156	0.26
chrY_2804248_2804778	0.04	ZFY	zinc finger protein, Y-linked	967	0.67
chr9_125662893_125663901	0.04	RC3H2	ring finger and CCCH-type domains 2	3008	0.16
chr5_126147731_126147991	0.04	LMNB1	lamin B1	34980	0.19
chr1_197730742_197731002	0.04	RP11-448G4.4		4423	0.25
chr7_43688967_43689164	0.04	COA1	cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)	830	0.67
chr1_112013416_112013602	0.04	C1orf162	chromosome 1 open reading frame 162	2905	0.14
chr19_42390602_42391041	0.04	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	2306	0.19
chr7_33078848_33079779	0.04	NT5C3A	5'-nucleotidase, cytosolic IIIA	1208	0.42
chr5_130882612_130883040	0.04	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	14100	0.29
chr1_100852790_100852941	0.04	ENSG00000216067	.	8534	0.21
chr3_151963607_151963763	0.04	MBNL1	muscleblind-like splicing regulator 1	22144	0.21
chr16_31271922_31272073	0.04	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	682	0.53
chr13_46745397_46745548	0.04	ENSG00000240767	.	1589	0.32
chr7_115668295_115668446	0.04	TFEC	transcription factor EC	2425	0.43
chr4_144312492_144312643	0.04	GAB1	GRB2-associated binding protein 1	96	0.98
chr12_47600587_47601314	0.04	PCED1B	PC-esterase domain containing 1B	9102	0.22
chr4_154411300_154411567	0.04	KIAA0922	KIAA0922	23932	0.22
chr2_174129320_174129481	0.04	MLK7-AS1	MLK7 antisense RNA 1	6948	0.3
chr17_10601145_10601947	0.04	ADPRM	ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent	635	0.41
chr1_24862040_24862255	0.04	ENSG00000266551	.	5943	0.18
chr11_128589269_128589524	0.04	SENCR	smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA	23478	0.17
chr17_28085648_28085799	0.04	RP11-82O19.1		2398	0.25
chr3_98253310_98253461	0.03	GPR15	G protein-coupled receptor 15	2642	0.21
chr10_26771389_26771611	0.03	ENSG00000199733	.	27018	0.21
chr16_50776896_50777610	0.03	RP11-327F22.1		527	0.39
chr15_55547653_55548107	0.03	RAB27A	RAB27A, member RAS oncogene family	6647	0.22
chr21_15917916_15918619	0.03	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	395	0.89
chr14_22977314_22977663	0.03	TRAJ15	T cell receptor alpha joining 15	21092	0.09
chr12_95071864_95072096	0.03	TMCC3	transmembrane and coiled-coil domain family 3	27642	0.23
chr1_150584633_150584820	0.03	ENSG00000253047	.	11591	0.1
chr16_81030456_81031156	0.03	CMC2	C-x(9)-C motif containing 2	1458	0.31
chr10_112632655_112633305	0.03	PDCD4-AS1	PDCD4 antisense RNA 1	989	0.38
chr11_128392558_128393039	0.03	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	593	0.77
chr13_41372571_41372761	0.03	SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	5372	0.18
chr12_131796680_131796831	0.03	ENSG00000212251	.	12459	0.23
chrX_129243329_129244377	0.03	ELF4	E74-like factor 4 (ets domain transcription factor)	483	0.82
chr19_6481304_6482171	0.03	DENND1C	DENN/MADD domain containing 1C	27	0.95
chr1_200987607_200987758	0.03	KIF21B	kinesin family member 21B	4854	0.21
chr18_56326442_56326593	0.03	MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	12101	0.14
chr1_200865204_200865355	0.03	C1orf106	chromosome 1 open reading frame 106	1330	0.42
chr22_31615175_31615326	0.03	ENSG00000199695	.	3589	0.13
chr12_8666250_8666401	0.03	CLEC4D	C-type lectin domain family 4, member D	189	0.93
chr3_108543496_108543820	0.03	TRAT1	T cell receptor associated transmembrane adaptor 1	2039	0.42
chr14_70111468_70111619	0.03	KIAA0247	KIAA0247	33230	0.18
chr1_206732541_206732911	0.03	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	2233	0.27
chr14_22747289_22747440	0.03	ENSG00000238634	.	136477	0.04
chr9_102849500_102849651	0.03	ERP44	endoplasmic reticulum protein 44	11747	0.18
chr13_46755198_46755455	0.03	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	1133	0.45
chr3_32996346_32996497	0.03	CCR4	chemokine (C-C motif) receptor 4	3355	0.33
chr3_69140694_69141185	0.03	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	6767	0.15
chr15_52844361_52844512	0.03	ARPP19	cAMP-regulated phosphoprotein, 19kDa	5505	0.2
chr21_32555155_32555306	0.03	TIAM1	T-cell lymphoma invasion and metastasis 1	52691	0.16
chr1_206753637_206754165	0.03	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	23408	0.13
chrX_9801459_9801610	0.03	ENSG00000206844	.	41207	0.15
chrX_13106517_13106711	0.03	FAM9C	family with sequence similarity 9, member C	43813	0.18
chr9_117721707_117721858	0.03	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	29085	0.23
chr1_39594945_39595096	0.03	ENSG00000206654	.	8305	0.17
chr12_65779210_65779361	0.03	MSRB3	methionine sulfoxide reductase B3	58630	0.15
chr2_99345755_99346000	0.03	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	834	0.68
chr5_81074467_81075538	0.03	SSBP2	single-stranded DNA binding protein 2	27930	0.25
chr1_231748956_231749347	0.03	LINC00582	long intergenic non-protein coding RNA 582	1315	0.46
chr18_57572017_57572168	0.03	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	4844	0.29
chr21_32559881_32560032	0.03	TIAM1	T-cell lymphoma invasion and metastasis 1	57417	0.15
chr17_21157480_21157631	0.03	C17orf103	chromosome 17 open reading frame 103	833	0.56
chr10_70850849_70851349	0.03	SRGN	serglycin	3225	0.25
chrX_118818753_118818904	0.03	SEPT6	septin 6	7964	0.18
chr20_1357596_1357769	0.03	RP11-314N13.3		15416	0.13
chr17_74564111_74564262	0.03	RP11-666A8.9		1688	0.17
chr14_22955963_22956254	0.03	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	63	0.95
chr1_236284065_236284436	0.03	GPR137B	G protein-coupled receptor 137B	21582	0.19
chr4_36243817_36244102	0.03	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	1602	0.35
chr7_94035982_94036133	0.03	COL1A2	collagen, type I, alpha 2	12184	0.27
chr7_37488846_37488997	0.03	ELMO1	engulfment and cell motility 1	69	0.98
chr15_44101218_44101369	0.03	HYPK	huntingtin interacting protein K	8496	0.08
chrX_35788537_35788688	0.03	MAGEB16	melanoma antigen family B, 16	27847	0.25
chr13_49065751_49065929	0.03	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	41373	0.17
chr17_75663137_75663644	0.03	SEPT9	septin 9	185395	0.03
chr11_104904746_104905919	0.03	CASP1	caspase 1, apoptosis-related cysteine peptidase	508	0.77
chr4_91603417_91603568	0.03	CCSER1	coiled-coil serine-rich protein 1	32830	0.25
chr10_7526759_7527322	0.03	ENSG00000207453	.	1731	0.45
chr8_27223967_27224118	0.03	PTK2B	protein tyrosine kinase 2 beta	14126	0.22
chr3_63954713_63955178	0.03	ATXN7	ataxin 7	1525	0.34
chr1_111215065_111215351	0.03	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	2447	0.28
chr12_65013240_65013416	0.03	ENSG00000207546	.	2961	0.17
chr11_20179312_20179463	0.03	DBX1	developing brain homeobox 1	2483	0.35
chr10_1779633_1779784	0.03	ADARB2	adenosine deaminase, RNA-specific, B2 (non-functional)	38	0.99
chr14_22182172_22182323	0.03	OR4E2	olfactory receptor, family 4, subfamily E, member 2	48950	0.13
chr10_134261699_134261957	0.03	C10orf91	chromosome 10 open reading frame 91	3135	0.24
chr1_90290694_90290845	0.03	LRRC8D	leucine rich repeat containing 8 family, member D	3289	0.28
chr9_184434_184636	0.03	CBWD1	COBW domain containing 1	5463	0.2
chr3_124774787_124775424	0.03	HEG1	heart development protein with EGF-like domains 1	303	0.88
chr2_136876136_136876323	0.03	CXCR4	chemokine (C-X-C motif) receptor 4	494	0.87
chr17_37933702_37934037	0.03	IKZF3	IKAROS family zinc finger 3 (Aiolos)	609	0.66
chr4_40201423_40201705	0.03	RHOH	ras homolog family member H	400	0.87
chr18_74837172_74837323	0.03	MBP	myelin basic protein	2421	0.42
chr14_90187580_90187856	0.03	ENSG00000200312	.	8863	0.23
chr1_206749362_206749620	0.03	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	18998	0.14
chr9_92032170_92032321	0.03	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	1503	0.49
chr17_56736328_56736479	0.03	ENSG00000202077	.	263	0.86
chr2_64369947_64371114	0.03	AC074289.1		157	0.93
chr2_197032053_197032740	0.03	STK17B	serine/threonine kinase 17b	3328	0.25
chr2_175458036_175458370	0.03	WIPF1	WAS/WASL interacting protein family, member 1	4290	0.21
chr9_70851276_70851465	0.03	CBWD3	COBW domain containing 3	5027	0.19
chr3_195962656_195962807	0.03	SLC51A	solute carrier family 51, alpha subunit	5855	0.13
chr10_30745504_30745655	0.03	MAP3K8	mitogen-activated protein kinase kinase kinase 8	17828	0.21
chr6_36008402_36008553	0.03	MAPK14	mitogen-activated protein kinase 14	11611	0.19
chr1_198652510_198652661	0.03	RP11-553K8.5		16395	0.24
chr5_150593261_150593549	0.03	GM2A	GM2 ganglioside activator	1694	0.36
chr8_82022711_82022967	0.03	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	1464	0.56
chr10_6626003_6626633	0.03	PRKCQ	protein kinase C, theta	4055	0.36
chr15_69074948_69075145	0.03	ENSG00000265195	.	19218	0.22
chrY_1551045_1551310	0.03	NA	NA	> 10⁶	NA
chr5_74615521_74615672	0.03	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	16558	0.19
chr7_17039488_17039788	0.03	AGR3	anterior gradient 3	118027	0.06
chr19_48832910_48833240	0.03	EMP3	epithelial membrane protein 3	4210	0.13
chr9_70495582_70495733	0.03	CBWD5	COBW domain containing 5	5411	0.29
chr1_66806017_66806168	0.03	PDE4B	phosphodiesterase 4B, cAMP-specific	8220	0.31
chr8_134086469_134086645	0.03	SLA	Src-like-adaptor	13954	0.23
chr9_80524074_80524374	0.03	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	86309	0.1
chr17_18204377_18204528	0.03	TOP3A	topoisomerase (DNA) III alpha	1531	0.27
chr14_75885513_75886422	0.03	RP11-293M10.6		8426	0.2
chr4_26269987_26270138	0.03	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	4167	0.36
chr9_69267993_69268163	0.03	CBWD6	COBW domain containing 6	5485	0.22
chr17_75450125_75450790	0.03	SEPT9	septin 9	295	0.88
chr6_167526422_167526606	0.03	CCR6	chemokine (C-C motif) receptor 6	1219	0.48
chr3_128899189_128899802	0.03	CNBP	CCHC-type zinc finger, nucleic acid binding protein	3247	0.18
chr3_107697576_107697727	0.03	CD47	CD47 molecule	79557	0.11
chr13_31312055_31312206	0.03	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	2485	0.4
chr1_21349011_21349508	0.03	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	28136	0.19
chr3_47182364_47182515	0.03	SETD2	SET domain containing 2	22627	0.16
chr18_21572812_21573447	0.02	TTC39C	tetratricopeptide repeat domain 39C	392	0.85
chr4_90226799_90226950	0.02	GPRIN3	GPRIN family member 3	2287	0.45
chr3_135909805_135909956	0.02	MSL2	male-specific lethal 2 homolog (Drosophila)	3516	0.32
chr4_38623548_38623699	0.02	RP11-617D20.1		2573	0.31
chr11_75063727_75063930	0.02	ARRB1	arrestin, beta 1	955	0.48
chr4_25865391_25865542	0.02	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)	84	0.98
chr22_18260542_18260943	0.02	BID	BH3 interacting domain death agonist	3311	0.23
chr15_43531850_43532099	0.02	ENSG00000202211	.	7904	0.13
chr8_8203302_8203453	0.02	SGK223	Tyrosine-protein kinase SgK223	35880	0.18
chr2_197133486_197133637	0.02	AC020571.3		8404	0.2
chr12_90537525_90537676	0.02	ENSG00000252823	.	389764	0.01
chr9_79265748_79266757	0.02	PRUNE2	prune homolog 2 (Drosophila)	1213	0.53
chr10_54463336_54463751	0.02	RP11-556E13.1		51626	0.16
chr6_20174159_20174424	0.02	RP11-239H6.2		38027	0.18
chr14_91863541_91863979	0.02	CCDC88C	coiled-coil domain containing 88C	19930	0.21
chr14_75990505_75990656	0.02	BATF	basic leucine zipper transcription factor, ATF-like	1677	0.38
chr6_170597990_170598273	0.02	DLL1	delta-like 1 (Drosophila)	1430	0.33
chr10_73847731_73848399	0.02	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	21	0.98
chr1_158802859_158803010	0.02	MNDA	myeloid cell nuclear differentiation antigen	1827	0.35
chr11_104940824_104940975	0.02	CARD16	caspase recruitment domain family, member 16	24796	0.15
chr4_106070591_106071096	0.02	TET2	tet methylcytosine dioxygenase 2	2229	0.34
chr8_66843424_66843611	0.02	PDE7A	phosphodiesterase 7A	89330	0.09
chrX_1600809_1601304	0.02	ASMTL	acetylserotonin O-methyltransferase-like	28401	0.16
chr17_29644876_29645027	0.02	CTD-2370N5.3		707	0.55
chr11_82882204_82882391	0.02	PCF11	PCF11 cleavage and polyadenylation factor subunit	4	0.97
chr2_175498105_175498391	0.02	WIPF1	WAS/WASL interacting protein family, member 1	1059	0.58

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NOTO_VSX2_DLX2_DLX6_NKX6-1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	GO:0010447	response to acidic pH(GO:0010447)
0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	GO:0030011	maintenance of cell polarity(GO:0030011)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)

Results for NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 0.31

Motif logo

Transcription factors associated with NOTO_VSX2_DLX2_DLX6_NKX6-1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the NOTO_VSX2_DLX2_DLX6_NKX6-1 motif across conditions

Conditions sorted by the z-value of the NOTO_VSX2_DLX2_DLX6_NKX6-1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NOTO_VSX2_DLX2_DLX6_NKX6-1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in molecular function category: