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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR1D1

Z-value: 0.83

Motif logo

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Transcription factors associated with NR1D1

Gene Symbol Gene ID Gene Info
NR1D1
ENSG00000126368.5 NR1D1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NR1D1chr17_38255735_382569626300.599245-0.703.6e-02Click!
NR1D1chr17_38267322_38267473104190.112073-0.655.6e-02Click!
NR1D1chr17_38264116_3826434272510.119112-0.608.8e-02Click!
NR1D1chr17_38252430_3825258144730.1347970.521.5e-01Click!
NR1D1chr17_38254187_3825462725710.176473-0.491.8e-01Click!

Activity of the NR1D1 motif across conditions

Conditions sorted by the z-value of the NR1D1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_49627195_49627425 0.45 TUBA1C
 tubulin, alpha 1c
 5601
 0.13
chr1_249097926_249098077 0.42 SH3BP5L
 SH3-binding domain protein 5-like
 13271
 0.15
chr2_207972488_207972682 0.40 ENSG00000253008
 .
 2212
 0.31
chr2_201559806_201559957 0.35 AOX1
 aldehyde oxidase 1
 32251
 0.16
chr7_508860_509011 0.34 PDGFA
 platelet-derived growth factor alpha polypeptide
 49210
 0.14
chr19_20067439_20067590 0.33 AC007204.1
 Uncharacterized protein
 18875
 0.14
chr15_50404394_50404634 0.31 ATP8B4
 ATPase, class I, type 8B, member 4
 2187
 0.37
chr11_48057635_48057786 0.31 AC103828.1
20303
 0.19
chr1_249097665_249097816 0.30 SH3BP5L
 SH3-binding domain protein 5-like
 13532
 0.15
chr12_123754396_123755524 0.30 CDK2AP1
 cyclin-dependent kinase 2 associated protein 1
 728
 0.52
chr10_75626090_75626284 0.30 CAMK2G
 calcium/calmodulin-dependent protein kinase II gamma
 5575
 0.13
chr1_38412223_38412952 0.29 INPP5B
 inositol polyphosphate-5-phosphatase, 75kDa
 136
 0.94
chr1_249097046_249097197 0.29 SH3BP5L
 SH3-binding domain protein 5-like
 14151
 0.15
chr7_26141005_26141262 0.28 ENSG00000266430
 .
 41174
 0.15
chr9_71590240_71590555 0.28 PRKACG
 protein kinase, cAMP-dependent, catalytic, gamma
 38642
 0.15
chr3_32433354_32434295 0.26 CMTM7
 CKLF-like MARVEL transmembrane domain containing 7
 293
 0.93
chr17_32582682_32583141 0.26 AC005549.3
 Uncharacterized protein
 605
 0.41
chr7_45039935_45040086 0.26 CCM2
 cerebral cavernous malformation 2
 223
 0.91
chr2_232419167_232419527 0.26 NMUR1
 neuromedin U receptor 1
 24141
 0.13
chr2_232186481_232186632 0.26 ENSG00000263641
 .
 40863
 0.13
chr12_54758511_54758662 0.25 GPR84
 G protein-coupled receptor 84
 315
 0.77
chr12_111843881_111845308 0.25 SH2B3
 SH2B adaptor protein 3
 842
 0.62
chr7_130071040_130071220 0.24 CEP41
 centrosomal protein 41kDa
 4310
 0.17
chr17_7959293_7959452 0.24 ALOX15B
 arachidonate 15-lipoxygenase, type B
 16898
 0.09
chr1_9124419_9124586 0.24 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
 5102
 0.18
chr12_71003154_71004126 0.23 PTPRB
 protein tyrosine phosphatase, receptor type, B
 16
 0.99
chr11_82608865_82609016 0.22 C11orf82
 chromosome 11 open reading frame 82
 2077
 0.29
chr9_35489468_35490886 0.22 RUSC2
 RUN and SH3 domain containing 2
 53
 0.97
chr19_41932700_41933275 0.22 B3GNT8
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
 1648
 0.18
chr4_175344904_175345055 0.22 ENSG00000265846
 .
 33
 0.99
chr5_176783043_176783194 0.21 RGS14
 regulator of G-protein signaling 14
 1720
 0.2
chr5_98362367_98362646 0.21 ENSG00000200351
 .
 90055
 0.09
chr22_38029329_38029754 0.21 SH3BP1
 SH3-domain binding protein 1
 5941
 0.11
chr1_212731391_212732317 0.21 ATF3
 activating transcription factor 3
 6822
 0.21
chr6_25206992_25207143 0.21 ENSG00000264238
 .
 3586
 0.22
chr9_7976512_7976663 0.21 TMEM261
 transmembrane protein 261
 176520
 0.04
chr4_8263855_8264006 0.21 HTRA3
 HtrA serine peptidase 3
 7562
 0.22
chr7_81267749_81267900 0.20 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
 124488
 0.06
chr17_20491916_20492779 0.20 CDRT15L2
 CMT1A duplicated region transcript 15-like 2
 9310
 0.21
chr4_159738305_159738456 0.20 FNIP2
 folliculin interacting protein 2
 10980
 0.21
chr19_4473895_4474732 0.20 HDGFRP2
 Hepatoma-derived growth factor-related protein 2
 576
 0.53
chr9_139559538_139560114 0.20 EGFL7
 EGF-like-domain, multiple 7
 418
 0.68
chr2_54808515_54808696 0.20 SPTBN1
 spectrin, beta, non-erythrocytic 1
 23074
 0.17
chr17_71287404_71287786 0.19 CDC42EP4
 CDC42 effector protein (Rho GTPase binding) 4
 19952
 0.15
chr20_62238249_62238400 0.19 GMEB2
 glucocorticoid modulatory element binding protein 2
 2069
 0.19
chrX_119259306_119259683 0.19 RP4-755D9.1
5032
 0.19
chr3_4520313_4520464 0.19 SUMF1
 sulfatase modifying factor 1
 11423
 0.2
chr1_21851738_21851889 0.19 ALPL
 alkaline phosphatase, liver/bone/kidney
 15948
 0.2
chr9_139837883_139838667 0.18 FBXW5
 F-box and WD repeat domain containing 5
 711
 0.36
chr6_134438521_134438724 0.18 ENSG00000266875
 .
 16089
 0.21
chr19_43027430_43027581 0.18 CEACAM1
 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
 4469
 0.2
chr1_16554480_16554631 0.18 ANO7P1
 anoctamin 7 pseudogene 1
 33
 0.95
chr6_165722551_165723097 0.18 C6orf118
 chromosome 6 open reading frame 118
 272
 0.95
chr10_102108013_102108269 0.17 SCD
 stearoyl-CoA desaturase (delta-9-desaturase)
 1260
 0.33
chr1_27951514_27951705 0.17 FGR
 feline Gardner-Rasheed sarcoma viral oncogene homolog
 1036
 0.44
chrX_117347179_117347330 0.17 KLHL13
 kelch-like family member 13
 95951
 0.08
chr7_134469863_134470014 0.17 CALD1
 caldesmon 1
 5509
 0.31
chr13_45753588_45753739 0.17 KCTD4
 potassium channel tetramerization domain containing 4
 15189
 0.17
chr11_114178829_114179071 0.17 NNMT
 nicotinamide N-methyltransferase
 10077
 0.21
chr1_206689423_206689574 0.16 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 8619
 0.15
chr14_23235943_23236779 0.16 OXA1L
 oxidase (cytochrome c) assembly 1-like
 433
 0.52
chr15_75336418_75336696 0.16 PPCDC
 phosphopantothenoylcysteine decarboxylase
 941
 0.52
chr17_38279440_38280347 0.16 MSL1
 male-specific lethal 1 homolog (Drosophila)
 937
 0.43
chr22_43358143_43358294 0.16 PACSIN2
 protein kinase C and casein kinase substrate in neurons 2
 2313
 0.35
chr9_91604330_91604481 0.16 C9orf47
 chromosome 9 open reading frame 47
 1373
 0.4
chr22_17739469_17739620 0.16 CECR1
 cat eye syndrome chromosome region, candidate 1
 36665
 0.16
chr10_11784750_11785238 0.16 ECHDC3
 enoyl CoA hydratase domain containing 3
 549
 0.83
chr4_151204575_151204726 0.15 LRBA
 LPS-responsive vesicle trafficking, beach and anchor containing
 19213
 0.26
chr2_109253274_109253425 0.15 LIMS1
 LIM and senescent cell antigen-like domains 1
 15627
 0.21
chr7_143082052_143082462 0.15 ZYX
 zyxin
 2164
 0.18
chr10_108923955_108924106 0.15 SORCS1
 sortilin-related VPS10 domain containing receptor 1
 254
 0.96
chrX_9310842_9311361 0.15 TBL1X
 transducin (beta)-like 1X-linked
 120234
 0.06
chr1_36042987_36043882 0.15 RP4-728D4.2
104
 0.95
chr9_92054863_92055014 0.15 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 3540
 0.31
chr10_102759781_102760726 0.15 LZTS2
 leucine zipper, putative tumor suppressor 2
 643
 0.52
chr10_82264222_82264373 0.15 RP11-137H2.4
31401
 0.16
chr17_75120485_75120909 0.15 SEC14L1
 SEC14-like 1 (S. cerevisiae)
 3258
 0.26
chr5_146256062_146256213 0.15 PPP2R2B
 protein phosphatase 2, regulatory subunit B, beta
 2068
 0.41
chr11_36412455_36412606 0.15 RP11-514F3.5
4459
 0.22
chr19_49465738_49466010 0.15 FTL
 ferritin, light polypeptide
 2684
 0.11
chr1_160635203_160635434 0.15 RP11-404F10.2
5250
 0.17
chr2_152215166_152215348 0.15 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
 1151
 0.45
chr14_33403030_33403481 0.15 NPAS3
 neuronal PAS domain protein 3
 884
 0.76
chr13_49435905_49436056 0.15 ENSG00000265585
 .
 68368
 0.11
chr11_124627874_124628025 0.15 RP11-677M14.3
1076
 0.32
chr1_8557419_8557570 0.15 ENSG00000221083
 .
 14484
 0.21
chr2_5367157_5367308 0.15 ENSG00000207192
 .
 374365
 0.01
chr15_74222160_74222311 0.15 LOXL1-AS1
 LOXL1 antisense RNA 1
 1646
 0.29
chr11_124752266_124752462 0.14 RP11-664I21.5
1223
 0.3
chr3_150995573_150995821 0.14 P2RY14
 purinergic receptor P2Y, G-protein coupled, 14
 460
 0.8
chr3_128943995_128944272 0.14 COPG1
 coatomer protein complex, subunit gamma 1
 24316
 0.13
chr17_32583150_32583439 0.14 AC005549.3
 Uncharacterized protein
 988
 0.32
chr21_40378227_40378378 0.14 ENSG00000272015
 .
 111593
 0.06
chr20_62478644_62478873 0.14 AL158091.1
 Protein LOC100509861
 3485
 0.11
chr8_128003605_128003873 0.14 ENSG00000212451
 .
 319972
 0.01
chr2_129038014_129038165 0.14 HS6ST1
 heparan sulfate 6-O-sulfotransferase 1
 38062
 0.18
chr1_41706915_41707336 0.14 SCMH1
 sex comb on midleg homolog 1 (Drosophila)
 657
 0.8
chr12_46568114_46568265 0.14 SLC38A1
 solute carrier family 38, member 1
 93295
 0.09
chr15_64231749_64232239 0.14 RP11-111E14.1
11521
 0.22
chr7_36195851_36196117 0.14 EEPD1
 endonuclease/exonuclease/phosphatase family domain containing 1
 3107
 0.3
chr6_157388469_157388620 0.14 RP1-137K2.2
52296
 0.17
chr7_116228317_116228468 0.14 AC006159.4
17104
 0.18
chr21_40181513_40181664 0.14 ETS2
 v-ets avian erythroblastosis virus E26 oncogene homolog 2
 28
 0.99
chr3_47034351_47034502 0.14 NBEAL2
 neurobeachin-like 2
 2385
 0.28
chr5_67515256_67515407 0.14 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 3727
 0.29
chr12_117500658_117500867 0.14 TESC
 tescalcin
 16126
 0.25
chr2_7148515_7148666 0.14 RNF144A
 ring finger protein 144A
 11519
 0.24
chr12_115137987_115138212 0.14 TBX3
 T-box 3
 16130
 0.21
chr19_42144659_42144810 0.14 CEACAM4
 carcinoembryonic antigen-related cell adhesion molecule 4
 11292
 0.14
chr17_79396214_79396830 0.14 RP11-1055B8.7
 BAH and coiled-coil domain-containing protein 1
 8874
 0.11
chr9_140215453_140215604 0.14 NRARP
 NOTCH-regulated ankyrin repeat protein
 18825
 0.09
chr11_72452757_72453026 0.14 ARAP1
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
 10557
 0.12
chr10_15138786_15140121 0.14 RPP38
 ribonuclease P/MRP 38kDa subunit
 34
 0.62
chr22_35726479_35726752 0.13 ENSG00000266320
 .
 5018
 0.18
chr17_79375573_79375724 0.13 ENSG00000266392
 .
 1070
 0.35
chr3_119041182_119042341 0.13 ARHGAP31-AS1
 ARHGAP31 antisense RNA 1
 154
 0.94
chr7_32699949_32700100 0.13 ENSG00000207573
 .
 72569
 0.11
chr18_64350086_64350429 0.13 ENSG00000221536
 .
 29519
 0.24
chr19_18525487_18525638 0.13 SSBP4
 single stranded DNA binding protein 4
 4112
 0.1
chr21_47472818_47473242 0.13 AP001471.1
44414
 0.11
chr2_175546375_175546968 0.13 WIPF1
 WAS/WASL interacting protein family, member 1
 928
 0.66
chr10_30163714_30163865 0.13 SVIL
 supervillin
 139056
 0.05
chr14_89632118_89632412 0.13 FOXN3
 forkhead box N3
 14823
 0.28
chr14_103584850_103585001 0.13 TNFAIP2
 tumor necrosis factor, alpha-induced protein 2
 4873
 0.18
chr7_12151395_12151884 0.13 TMEM106B
 transmembrane protein 106B
 99228
 0.09
chr12_6493326_6493955 0.13 LTBR
 lymphotoxin beta receptor (TNFR superfamily, member 3)
 221
 0.89
chr10_134388453_134389007 0.13 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 32700
 0.18
chr2_40786004_40786155 0.13 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
 46504
 0.21
chr20_33864845_33865490 0.13 MMP24-AS1
 MMP24 antisense RNA 1
 663
 0.38
chr2_16083664_16083952 0.13 MYCNOS
 MYCN opposite strand
 1437
 0.36
chr7_26577801_26577952 0.13 KIAA0087
 KIAA0087
 531
 0.86
chr19_47732183_47732562 0.13 BBC3
 BCL2 binding component 3
 2079
 0.22
chr5_141215789_141215991 0.13 PCDH1
 protocadherin 1
 33264
 0.16
chr12_26348638_26349346 0.13 SSPN
 sarcospan
 386
 0.88
chr1_27882496_27882647 0.13 RP1-159A19.4
30255
 0.13
chr8_58716546_58716697 0.13 FAM110B
 family with sequence similarity 110, member B
 190492
 0.03
chr3_37534801_37534952 0.13 ITGA9
 integrin, alpha 9
 41266
 0.16
chr10_94452035_94452186 0.13 HHEX
 hematopoietically expressed homeobox
 498
 0.8
chr18_74189003_74189166 0.13 ZNF516
 zinc finger protein 516
 13651
 0.17
chr6_166900831_166900982 0.13 ENSG00000222958
 .
 22015
 0.16
chr1_11786795_11786946 0.13 AGTRAP
 angiotensin II receptor-associated protein
 9271
 0.12
chr18_3794614_3794765 0.12 ENSG00000238790
 .
 16628
 0.17
chr11_2404413_2404564 0.12 CD81
 CD81 molecule
 798
 0.47
chr17_79421896_79422047 0.12 ENSG00000266189
 .
 3757
 0.13
chr20_62739628_62739779 0.12 NPBWR2
 neuropeptides B/W receptor 2
 1179
 0.33
chr4_99535433_99535584 0.12 TSPAN5
 tetraspanin 5
 43278
 0.16
chr10_45874400_45874551 0.12 ALOX5
 arachidonate 5-lipoxygenase
 4800
 0.27
chr5_154093938_154094089 0.12 LARP1
 La ribonucleoprotein domain family, member 1
 1551
 0.33
chr8_52798262_52798413 0.12 RP11-110G21.2
10597
 0.18
chr8_87052179_87052395 0.12 PSKH2
 protein serine kinase H2
 29639
 0.19
chr3_133287095_133287246 0.12 CDV3
 CDV3 homolog (mouse)
 5404
 0.22
chr6_46458824_46459774 0.12 RCAN2
 regulator of calcineurin 2
 200
 0.78
chr9_69261149_69261300 0.12 CBWD6
 COBW domain containing 6
 1285
 0.46
chr10_15503569_15503720 0.12 FAM171A1
 family with sequence similarity 171, member A1
 90583
 0.09
chr19_8567892_8568043 0.12 PRAM1
 PML-RARA regulated adaptor molecule 1
 29
 0.96
chr2_38265076_38265999 0.12 RMDN2-AS1
 RMDN2 antisense RNA 1
 2053
 0.33
chr20_43987050_43987201 0.12 SYS1
 SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
 3452
 0.15
chr2_27296685_27296836 0.12 OST4
 oligosaccharyltransferase 4 homolog (S. cerevisiae)
 2119
 0.12
chr21_43882491_43882642 0.12 SLC37A1
 solute carrier family 37 (glucose-6-phosphate transporter), member 1
 33562
 0.1
chr7_38296522_38296673 0.12 STARD3NL
 STARD3 N-terminal like
 78600
 0.11
chrX_153962751_153963096 0.12 GAB3
 GRB2-associated binding protein 3
 16409
 0.12
chr12_4397764_4397915 0.12 CCND2-AS1
 CCND2 antisense RNA 1
 12489
 0.16
chr11_123106721_123106884 0.12 CLMP
 CXADR-like membrane protein
 40813
 0.14
chr17_1090163_1090534 0.12 ABR
 active BCR-related
 268
 0.91
chr1_156124803_156124988 0.12 SEMA4A
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
 733
 0.51
chr1_98515040_98515403 0.12 ENSG00000225206
 .
 3494
 0.38
chr12_71551766_71551917 0.12 TSPAN8
 tetraspanin 8
 38
 0.98
chrX_150565701_150566113 0.12 VMA21
 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
 231
 0.96
chr1_28209156_28209307 0.12 THEMIS2
 thymocyte selection associated family member 2
 2989
 0.16
chr10_104411475_104411626 0.12 TRIM8
 tripartite motif containing 8
 6906
 0.18
chr16_27248668_27248966 0.12 NSMCE1
 non-SMC element 1 homolog (S. cerevisiae)
 4418
 0.19
chr15_89680666_89681045 0.12 ENSG00000239151
 .
 16845
 0.18
chr2_232226788_232226939 0.12 ENSG00000263641
 .
 556
 0.75
chr22_43369638_43369789 0.12 PACSIN2
 protein kinase C and casein kinase substrate in neurons 2
 13808
 0.21
chr4_1006679_1006830 0.12 FGFRL1
 fibroblast growth factor receptor-like 1
 515
 0.71
chr13_38445031_38445182 0.12 TRPC4
 transient receptor potential cation channel, subfamily C, member 4
 544
 0.83
chr21_39543980_39544194 0.12 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
 14959
 0.18
chr8_27219392_27219619 0.12 PTK2B
 protein tyrosine kinase 2 beta
 18663
 0.21
chr16_88980980_88981131 0.12 CBFA2T3
 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
 12132
 0.11
chr2_105458782_105459564 0.11 LINC01158
 long intergenic non-protein coding RNA 1158
 8738
 0.14
chr7_134854914_134855228 0.11 C7orf49
 chromosome 7 open reading frame 49
 342
 0.81
chr1_88368784_88369082 0.11 ENSG00000199318
 .
 449877
 0.01
chr6_109288373_109288524 0.11 RP11-787I22.3
31237
 0.15
chr2_131094823_131095064 0.11 IMP4
 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
 4855
 0.17
chr22_40659716_40659867 0.11 TNRC6B
 trinucleotide repeat containing 6B
 1216
 0.56
chr7_93812562_93812751 0.11 BET1
 Bet1 golgi vesicular membrane trafficking protein
 178962
 0.03
chr3_66535668_66535819 0.11 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
 15613
 0.29
chr11_128564573_128565732 0.11 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 766
 0.51
chr5_148747021_148747172 0.11 RP11-394O4.3
4641
 0.13
chr4_185268616_185268767 0.11 ENSG00000244512
 .
 68602
 0.09
chr11_93868067_93868416 0.11 PANX1
 pannexin 1
 6146
 0.28
chr15_91285368_91285519 0.11 ENSG00000200677
 .
 13099
 0.14
chr7_101525780_101526170 0.11 CTA-339C12.1
57966
 0.12
chr2_242605024_242605218 0.11 ATG4B
 autophagy related 4B, cysteine peptidase
 890
 0.44
chr16_89042423_89042673 0.11 CBFA2T3
 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
 853
 0.55
chr8_134706257_134706408 0.11 ENSG00000212273
 .
 49364
 0.19
chr17_40729237_40729659 0.11 PSMC3IP
 PSMC3 interacting protein
 266
 0.8
chr11_64512499_64513555 0.11 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
 99
 0.95
chr15_101995655_101995861 0.11 PCSK6
 proprotein convertase subtilisin/kexin type 6
 11890
 0.25
chr19_22817145_22817689 0.11 ZNF492
 zinc finger protein 492
 291
 0.89

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR1D1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.2 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.0 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.0 0.0 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.0 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0051299 centrosome separation(GO:0051299)
0.0 0.0 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors