Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR1I3

Z-value: 0.66

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Transcription factors associated with NR1I3

Gene Symbol Gene ID Gene Info
NR1I3
ENSG00000143257.7 NR1I3

Activity of the NR1I3 motif across conditions

Conditions sorted by the z-value of the NR1I3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_36398415_36398818 0.51 TYROBP
 TYRO protein tyrosine kinase binding protein
 533
 0.58
chr19_6773186_6773436 0.44 VAV1
 vav 1 guanine nucleotide exchange factor
 342
 0.82
chr10_134369040_134369355 0.39 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 17554
 0.21
chr7_106506867_106507018 0.31 PIK3CG
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
 1018
 0.65
chr17_1548578_1548729 0.28 SCARF1
 scavenger receptor class F, member 1
 385
 0.74
chr16_29674660_29674967 0.28 QPRT
 quinolinate phosphoribosyltransferase
 213
 0.51
chr1_161186326_161186719 0.27 FCER1G
 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
 1435
 0.17
chr8_142099867_142100113 0.26 DENND3
 DENN/MADD domain containing 3
 27387
 0.18
chr1_42230520_42230906 0.25 ENSG00000264896
 .
 5901
 0.3
chr7_43804203_43804455 0.24 BLVRA
 biliverdin reductase A
 539
 0.79
chr7_116655483_116655634 0.23 ST7
 suppression of tumorigenicity 7
 568
 0.75
chr16_53552847_53552998 0.23 AKTIP
 AKT interacting protein
 14599
 0.21
chr1_169662937_169663139 0.23 SELL
 selectin L
 17801
 0.18
chr9_140541651_140541974 0.21 EHMT1
 euchromatic histone-lysine N-methyltransferase 1
 28358
 0.12
chr7_17246351_17246502 0.21 AC003075.4
74501
 0.11
chr20_4792810_4792961 0.21 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
 2884
 0.28
chr1_109705357_109705508 0.21 ENSG00000238310
 .
 45038
 0.08
chr6_133089264_133089460 0.20 VNN2
 vanin 2
 4764
 0.14
chr9_136727962_136728162 0.19 SARDH
 sarcosine dehydrogenase
 122985
 0.05
chr8_116889935_116890086 0.19 TRPS1
 trichorhinophalangeal syndrome I
 68111
 0.14
chr16_50747073_50747224 0.19 RP11-327F22.6
393
 0.68
chr13_96205566_96205866 0.19 CLDN10
 claudin 10
 737
 0.72
chr2_27109742_27109997 0.18 DPYSL5
 dihydropyrimidinase-like 5
 38493
 0.13
chr8_90868157_90868315 0.18 ENSG00000207359
 .
 44816
 0.15
chr17_7920233_7920425 0.18 GUCY2D
 guanylate cyclase 2D, membrane (retina-specific)
 14417
 0.1
chr8_24151584_24151953 0.17 ADAM28
 ADAM metallopeptidase domain 28
 144
 0.97
chr11_47380887_47381038 0.17 MYBPC3
 myosin binding protein C, cardiac
 6709
 0.11
chr1_44985301_44985452 0.17 ENSG00000263381
 .
 25789
 0.18
chr12_9889522_9889673 0.16 CLECL1
 C-type lectin-like 1
 3702
 0.19
chr20_47402410_47402561 0.16 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 41935
 0.17
chr7_101460813_101461304 0.16 CUX1
 cut-like homeobox 1
 138
 0.97
chr4_6911822_6912351 0.16 TBC1D14
 TBC1 domain family, member 14
 111
 0.97
chr20_5634032_5634183 0.16 GPCPD1
 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
 42435
 0.18
chr21_27942979_27943130 0.16 CYYR1
 cysteine/tyrosine-rich 1
 2441
 0.43
chr15_70017287_70017438 0.16 ENSG00000238870
 .
 5799
 0.29
chr2_208999817_208999981 0.16 CRYGC
 crystallin, gamma C
 5345
 0.12
chr17_28053735_28053927 0.16 RP11-82O19.1
34290
 0.11
chrX_71299756_71300007 0.15 RGAG4
 retrotransposon gag domain containing 4
 51797
 0.11
chr22_31625332_31625483 0.15 ENSG00000202019
 .
 751
 0.5
chr11_58912766_58913207 0.15 FAM111A
 family with sequence similarity 111, member A
 450
 0.8
chr6_37017654_37018643 0.15 COX6A1P2
 cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
 5541
 0.22
chr12_112215247_112215398 0.15 ALDH2
 aldehyde dehydrogenase 2 family (mitochondrial)
 10596
 0.18
chr16_87993472_87993623 0.15 BANP
 BTG3 associated nuclear protein
 70
 0.98
chr10_11214521_11214797 0.15 RP3-323N1.2
1320
 0.48
chr11_128585758_128586117 0.15 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 20019
 0.17
chr13_110307530_110307681 0.15 LINC00676
 long intergenic non-protein coding RNA 676
 73024
 0.13
chr19_16698681_16699367 0.15 CTD-3222D19.5
228
 0.74
chr12_104963796_104963969 0.14 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 18744
 0.22
chr18_9488845_9488996 0.14 RALBP1
 ralA binding protein 1
 12787
 0.15
chrX_48542477_48542733 0.14 WAS
 Wiskott-Aldrich syndrome
 437
 0.75
chr5_14173969_14174187 0.14 TRIO
 trio Rho guanine nucleotide exchange factor
 9829
 0.32
chr15_91383344_91383495 0.14 CTD-3094K11.1
465
 0.73
chr5_147184374_147184525 0.14 JAKMIP2
 janus kinase and microtubule interacting protein 2
 22111
 0.17
chr5_10445338_10445751 0.14 ROPN1L
 rhophilin associated tail protein 1-like
 3556
 0.18
chr10_73506779_73506930 0.14 C10orf105
 chromosome 10 open reading frame 105
 9273
 0.2
chr14_103585199_103585350 0.14 TNFAIP2
 tumor necrosis factor, alpha-induced protein 2
 4524
 0.19
chr3_29185770_29185921 0.13 ENSG00000238470
 .
 133112
 0.05
chr8_134532733_134532928 0.13 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 21204
 0.27
chr17_80057367_80057586 0.13 FASN
 fatty acid synthase
 1268
 0.24
chr15_70827379_70827556 0.13 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 167153
 0.04
chr20_19638965_19639116 0.13 ENSG00000232675
 .
 35811
 0.18
chr1_153363293_153363489 0.13 S100A8
 S100 calcium binding protein A8
 61
 0.95
chr16_90169651_90169802 0.13 PRDM7
 PR domain containing 7
 27388
 0.14
chr17_2700217_2700494 0.13 RAP1GAP2
 RAP1 GTPase activating protein 2
 579
 0.74
chr9_137335451_137335655 0.13 RXRA
 retinoid X receptor, alpha
 37125
 0.19
chr17_80833603_80833820 0.13 TBCD
 tubulin folding cofactor D
 8317
 0.18
chr6_159464766_159465080 0.13 TAGAP
 T-cell activation RhoGTPase activating protein
 1127
 0.51
chrX_53342784_53342935 0.13 IQSEC2
 IQ motif and Sec7 domain 2
 7663
 0.18
chrX_77582442_77582995 0.13 CYSLTR1
 cysteinyl leukotriene receptor 1
 262
 0.96
chr19_48833533_48834100 0.13 EMP3
 epithelial membrane protein 3
 4951
 0.12
chr2_152148385_152148674 0.12 NMI
 N-myc (and STAT) interactor
 1958
 0.35
chr13_41588793_41589349 0.12 ELF1
 E74-like factor 1 (ets domain transcription factor)
 4379
 0.23
chr6_2733092_2733243 0.12 MYLK4
 myosin light chain kinase family, member 4
 17987
 0.2
chr12_96792273_96792988 0.12 CDK17
 cyclin-dependent kinase 17
 512
 0.8
chr4_16271608_16271759 0.12 TAPT1-AS1
 TAPT1 antisense RNA 1 (head to head)
 43015
 0.15
chr16_16170769_16170920 0.12 ABCC1
 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
 67131
 0.11
chr15_75160410_75160789 0.12 SCAMP2
 secretory carrier membrane protein 2
 4782
 0.12
chr17_48907044_48907195 0.12 WFIKKN2
 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
 4892
 0.17
chr10_77189804_77189955 0.12 RP11-399K21.10
1467
 0.43
chr17_28048860_28049057 0.12 RP11-82O19.1
39163
 0.1
chr1_38469725_38469960 0.12 FHL3
 four and a half LIM domains 3
 1335
 0.32
chr11_118095313_118095652 0.12 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 254
 0.89
chr11_47615011_47615162 0.12 C1QTNF4
 C1q and tumor necrosis factor related protein 4
 1125
 0.28
chr21_46302756_46302907 0.12 PTTG1IP
 pituitary tumor-transforming 1 interacting protein
 9079
 0.12
chr8_95917651_95917917 0.11 ENSG00000238791
 .
 563
 0.66
chrX_153979641_153979978 0.11 GAB3
 GRB2-associated binding protein 3
 457
 0.73
chr2_44397166_44397731 0.11 PPM1B
 protein phosphatase, Mg2+/Mn2+ dependent, 1B
 1399
 0.32
chr4_37603077_37603228 0.11 RP11-36B15.1
12655
 0.21
chr18_19284100_19284279 0.11 ABHD3
 abhydrolase domain containing 3
 403
 0.75
chr22_39493202_39493353 0.11 APOBEC3H
 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
 3
 0.97
chr20_57582980_57583192 0.11 CTSZ
 cathepsin Z
 784
 0.56
chr9_88357119_88357540 0.11 AGTPBP1
 ATP/GTP binding protein 1
 385
 0.93
chr14_91869059_91869463 0.11 CCDC88C
 coiled-coil domain containing 88C
 14429
 0.23
chr1_12149159_12149310 0.11 ENSG00000201135
 .
 11193
 0.15
chr22_38199332_38199483 0.11 H1F0
 H1 histone family, member 0
 1707
 0.2
chr17_56744023_56744174 0.11 ENSG00000199426
 .
 40
 0.96
chr2_216871280_216871528 0.11 MREG
 melanoregulin
 6942
 0.25
chr18_47012500_47013343 0.11 C18orf32
 chromosome 18 open reading frame 32
 62
 0.8
chr12_51319016_51319581 0.11 METTL7A
 methyltransferase like 7A
 764
 0.59
chr8_121761934_121762232 0.11 RP11-713M15.1
11410
 0.25
chr16_55471445_55471596 0.11 MMP2
 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
 41222
 0.16
chr3_16978815_16978966 0.11 ENSG00000264818
 .
 4202
 0.26
chr1_12227882_12228546 0.10 TNFRSF1B
 tumor necrosis factor receptor superfamily, member 1B
 1154
 0.44
chr21_46078204_46078355 0.10 KRTAP12-3
 keratin associated protein 12-3
 430
 0.64
chr5_58055562_58056142 0.10 RP11-479O16.1
24754
 0.24
chr4_15704055_15704284 0.10 BST1
 bone marrow stromal cell antigen 1
 404
 0.85
chr2_64834665_64834935 0.10 ENSG00000252414
 .
 28774
 0.17
chr3_185903259_185903649 0.10 ETV5
 ets variant 5
 75347
 0.1
chr4_120983549_120983700 0.10 RP11-679C8.2
4489
 0.25
chr11_61124561_61124712 0.10 CYB561A3
 cytochrome b561 family, member A3
 115
 0.94
chr3_69140694_69141185 0.10 ARL6IP5
 ADP-ribosylation-like factor 6 interacting protein 5
 6767
 0.15
chr13_74276583_74277049 0.10 KLF12
 Kruppel-like factor 12
 292370
 0.01
chr20_47445241_47445454 0.10 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 927
 0.69
chr9_35775939_35776090 0.10 NPR2
 natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
 16137
 0.07
chr6_15268964_15269231 0.10 JARID2
 jumonji, AT rich interactive domain 2
 19954
 0.17
chr8_142129282_142129557 0.10 DENND3
 DENN/MADD domain containing 3
 2042
 0.34
chr17_62707569_62707720 0.10 RP13-104F24.1
47077
 0.12
chr3_58339519_58339685 0.10 PXK
 PX domain containing serine/threonine kinase
 20569
 0.17
chr1_198608071_198608226 0.10 PTPRC
 protein tyrosine phosphatase, receptor type, C
 1
 0.98
chr6_135644010_135644161 0.10 RP3-388E23.2
21379
 0.2
chr6_43612507_43612686 0.10 RSPH9
 radial spoke head 9 homolog (Chlamydomonas)
 187
 0.91
chr9_141108330_141108481 0.10 TUBBP5
 tubulin, beta pseudogene 5
 38908
 0.18
chr6_35696426_35696695 0.10 FKBP5
 FK506 binding protein 5
 200
 0.9
chr17_54759510_54759661 0.10 NOG
 noggin
 88525
 0.08
chr10_103608684_103608835 0.10 KCNIP2
 Kv channel interacting protein 2
 5082
 0.18
chr2_137140100_137140251 0.10 ENSG00000251976
 .
 7727
 0.32
chr10_49731303_49731459 0.10 ARHGAP22
 Rho GTPase activating protein 22
 900
 0.64
chr12_94601752_94602458 0.10 RP11-74K11.2
22285
 0.18
chr5_139971225_139971376 0.10 ENSG00000200235
 .
 12048
 0.08
chr20_5126928_5127079 0.10 CDS2
 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
 19392
 0.12
chr6_120039243_120039394 0.10 ENSG00000265725
 .
 297007
 0.01
chr2_71299748_71299899 0.09 NAGK
 N-acetylglucosamine kinase
 844
 0.45
chr3_49841438_49841709 0.09 FAM212A
 family with sequence similarity 212, member A
 886
 0.35
chr10_51566009_51566382 0.09 NCOA4
 nuclear receptor coactivator 4
 965
 0.54
chr14_77500493_77500704 0.09 IRF2BPL
 interferon regulatory factor 2 binding protein-like
 5564
 0.22
chr20_58633559_58633836 0.09 C20orf197
 chromosome 20 open reading frame 197
 2717
 0.35
chr10_14596775_14596926 0.09 FAM107B
 family with sequence similarity 107, member B
 622
 0.8
chr1_228457559_228457839 0.09 RP5-1139B12.2
4399
 0.14
chr20_44543417_44543568 0.09 PLTP
 phospholipid transfer protein
 2698
 0.13
chr2_73297200_73297351 0.09 SFXN5
 sideroflexin 5
 1527
 0.42
chr5_153652567_153652718 0.09 ENSG00000221070
 .
 67044
 0.1
chr17_38128484_38128998 0.09 GSDMA
 gasdermin A
 6965
 0.12
chr9_71160716_71160867 0.09 TMEM252
 transmembrane protein 252
 5008
 0.3
chr15_80274344_80274495 0.09 BCL2A1
 BCL2-related protein A1
 10631
 0.19
chr19_45250325_45250702 0.09 BCL3
 B-cell CLL/lymphoma 3
 1291
 0.3
chr3_4516286_4516499 0.09 SUMF1
 sulfatase modifying factor 1
 7427
 0.21
chr1_203186842_203186993 0.09 CHIT1
 chitinase 1 (chitotriosidase)
 11882
 0.15
chr4_113068308_113068459 0.09 C4orf32
 chromosome 4 open reading frame 32
 1830
 0.44
chr1_198901485_198902338 0.09 ENSG00000207759
 .
 73629
 0.11
chr20_826611_826818 0.09 FAM110A
 family with sequence similarity 110, member A
 947
 0.64
chrX_49047229_49047448 0.09 PRICKLE3
 prickle homolog 3 (Drosophila)
 4493
 0.09
chr19_7413904_7414409 0.09 CTB-133G6.1
308
 0.88
chr9_131550054_131550269 0.09 TBC1D13
 TBC1 domain family, member 13
 533
 0.64
chr12_48220962_48221113 0.09 HDAC7
 histone deacetylase 7
 5878
 0.17
chr11_46331268_46331419 0.09 CREB3L1
 cAMP responsive element binding protein 3-like 1
 1365
 0.39
chr6_20174159_20174424 0.09 RP11-239H6.2
38027
 0.18
chr16_53133173_53134292 0.09 CHD9
 chromodomain helicase DNA binding protein 9
 660
 0.77
chr12_29311473_29311703 0.09 FAR2
 fatty acyl CoA reductase 2
 9455
 0.26
chr12_118796178_118796667 0.09 TAOK3
 TAO kinase 3
 488
 0.85
chr3_195823637_195823788 0.09 TFRC
 transferrin receptor
 14652
 0.17
chr15_92404681_92404832 0.09 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
 7405
 0.27
chr1_183549128_183549279 0.09 NCF2
 neutrophil cytosolic factor 2
 10513
 0.2
chr17_56405277_56405428 0.09 BZRAP1
 benzodiazepine receptor (peripheral) associated protein 1
 93
 0.91
chr14_95650210_95650361 0.08 CTD-2240H23.2
1906
 0.28
chr1_230281012_230281163 0.08 GALNT2
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
 78069
 0.1
chr2_145139373_145139524 0.08 ZEB2
 zinc finger E-box binding homeobox 2
 48145
 0.16
chr6_96969080_96969553 0.08 UFL1-AS1
 UFL1 antisense RNA 1
 229
 0.65
chr20_61202559_61202764 0.08 ENSG00000207764
 .
 40542
 0.09
chr6_109621799_109621950 0.08 ENSG00000201023
 .
 4823
 0.21
chr2_178217813_178218079 0.08 ENSG00000238295
 .
 7257
 0.15
chr12_57107519_57107670 0.08 NACA
 nascent polypeptide-associated complex alpha subunit
 5790
 0.14
chr16_22200588_22200739 0.08 EEF2K
 eukaryotic elongation factor-2 kinase
 16940
 0.16
chr10_51574545_51574696 0.08 NCOA4
 nuclear receptor coactivator 4
 1320
 0.42
chr1_150536239_150536708 0.08 ADAMTSL4-AS1
 ADAMTSL4 antisense RNA 1
 2504
 0.12
chr11_44592282_44592433 0.08 CD82
 CD82 molecule
 2271
 0.34
chr12_32636420_32636776 0.08 FGD4
 FYVE, RhoGEF and PH domain containing 4
 2308
 0.33
chr12_116983809_116983960 0.08 MAP1LC3B2
 microtubule-associated protein 1 light chain 3 beta 2
 13302
 0.27
chr6_31508773_31509384 0.08 ENSG00000265236
 .
 123
 0.54
chr2_2689870_2690021 0.08 ENSG00000263570
 .
 331157
 0.01
chr20_39407503_39407654 0.08 ENSG00000238908
 .
 75291
 0.11
chr1_186587084_186587465 0.08 PTGS2
 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
 62285
 0.14
chr7_2648316_2648467 0.08 IQCE
 IQ motif containing E
 11858
 0.16
chr11_57194286_57194587 0.08 SLC43A3
 solute carrier family 43, member 3
 18
 0.95
chr14_73931285_73931436 0.08 ENSG00000251393
 .
 2231
 0.24
chr5_81148309_81148643 0.08 SSBP2
 single-stranded DNA binding protein 2
 101404
 0.07
chr19_42302514_42302665 0.08 CEACAM3
 carcinoembryonic antigen-related cell adhesion molecule 3
 1504
 0.28
chr1_14951057_14951208 0.08 KAZN
 kazrin, periplakin interacting protein
 25919
 0.28
chrX_45626469_45627939 0.08 ENSG00000207725
 .
 20674
 0.22
chr6_26155918_26156313 0.08 HIST1H1E
 histone cluster 1, H1e
 444
 0.58
chr21_40182599_40182907 0.08 ETS2
 v-ets avian erythroblastosis virus E26 oncogene homolog 2
 1193
 0.62
chr9_134001509_134001851 0.08 NUP214
 nucleoporin 214kDa
 213
 0.82
chr1_161008159_161008677 0.08 TSTD1
 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
 101
 0.93
chr1_198905629_198906537 0.08 ENSG00000207759
 .
 77801
 0.11
chr12_120675375_120675841 0.08 PXN
 paxillin
 10961
 0.12
chr17_9990899_9991143 0.08 ENSG00000221486
 .
 16814
 0.19
chr2_70144352_70144560 0.08 MXD1
 MAX dimerization protein 1
 2136
 0.21
chr1_182138764_182138915 0.08 ZNF648
 zinc finger protein 648
 107992
 0.07
chr14_65175690_65176293 0.08 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
 4676
 0.25
chr14_102976422_102976710 0.08 ANKRD9
 ankyrin repeat domain 9
 430
 0.81
chr9_93569356_93569567 0.08 SYK
 spleen tyrosine kinase
 5252
 0.35

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR1I3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.0 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.0 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.0 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.1 GO:0050901 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.1 GO:0003341 cilium movement(GO:0003341)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.0 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.0 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules