Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
Navigation
Downloads
Logo
CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR2E1

Z-value: 1.47

Motif logo

logo of

Transcription factors associated with NR2E1

Gene Symbol Gene ID Gene Info
NR2E1
ENSG00000112333.7 NR2E1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NR2E1chr6_108487390_1084875442050.724308-0.541.4e-01Click!
NR2E1chr6_108490756_1084909078640.581233-0.491.8e-01Click!
NR2E1chr6_108489604_1084897692810.896148-0.481.9e-01Click!
NR2E1chr6_108490135_1084907144570.803102-0.462.2e-01Click!
NR2E1chr6_108487569_1084877764100.615383-0.314.1e-01Click!

Activity of the NR2E1 motif across conditions

Conditions sorted by the z-value of the NR2E1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr4_74455010_74455326 0.56 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
 30961
 0.21
chr15_60684685_60685107 0.55 ANXA2
 annexin A2
 1400
 0.54
chr2_169377724_169378182 0.51 ENSG00000265694
 .
 61500
 0.1
chr11_85962233_85962384 0.47 EED
 embryonic ectoderm development
 6032
 0.24
chr9_85677185_85677712 0.47 RASEF
 RAS and EF-hand domain containing
 595
 0.84
chr22_33141802_33142090 0.46 LL22NC01-116C6.1
37217
 0.18
chr20_10399686_10399837 0.43 MKKS
 McKusick-Kaufman syndrome
 12809
 0.19
chr8_38899485_38899676 0.43 ENSG00000207199
 .
 23378
 0.15
chr4_4494063_4494282 0.43 STX18-IT1
 STX18 intronic transcript 1 (non-protein coding)
 10745
 0.21
chr6_140404065_140404365 0.43 ENSG00000252107
 .
 75616
 0.12
chr8_87354102_87354253 0.42 WWP1
 WW domain containing E3 ubiquitin protein ligase 1
 790
 0.74
chr5_38758917_38759276 0.42 RP11-122C5.3
24586
 0.23
chr3_149298860_149299373 0.42 WWTR1
 WW domain containing transcription regulator 1
 5077
 0.23
chr6_85101808_85101959 0.40 KIAA1009
 KIAA1009
 164530
 0.04
chr1_175946531_175946682 0.39 ENSG00000252906
 .
 8930
 0.26
chr5_24789253_24789404 0.39 ENSG00000223004
 .
 22262
 0.27
chr7_17348882_17349033 0.39 AC003075.4
9976
 0.22
chr6_131360061_131360448 0.39 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 23272
 0.26
chr2_144156290_144156486 0.39 AC096558.1
81962
 0.1
chr2_201351539_201351690 0.38 SGOL2
 shugoshin-like 2 (S. pombe)
 23117
 0.16
chr22_36233928_36234199 0.38 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 2202
 0.43
chr5_158477296_158477548 0.38 EBF1
 early B-cell factor 1
 49279
 0.14
chr8_108791551_108791785 0.38 ENSG00000200806
 .
 105054
 0.08
chr22_46443774_46444122 0.38 RP6-109B7.5
5025
 0.11
chr9_117879769_117880175 0.37 TNC
 tenascin C
 506
 0.85
chr22_24133174_24133325 0.37 SMARCB1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
 4051
 0.11
chr2_168406531_168406682 0.37 ENSG00000238357
 .
 81445
 0.12
chr6_8628285_8628436 0.37 SLC35B3
 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
 192566
 0.03
chr7_95545265_95545416 0.36 DYNC1I1
 dynein, cytoplasmic 1, intermediate chain 1
 111744
 0.07
chr21_23084240_23084391 0.36 ENSG00000221210
 .
 314169
 0.01
chr16_21289732_21289908 0.36 CRYM
 crystallin, mu
 26
 0.98
chr20_34458778_34459038 0.36 ENSG00000201221
 .
 16673
 0.13
chr13_31271674_31272060 0.36 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
 37778
 0.19
chr4_177114551_177114709 0.35 SPATA4
 spermatogenesis associated 4
 1398
 0.46
chr15_36623332_36623712 0.35 C15orf41
 chromosome 15 open reading frame 41
 248290
 0.02
chr11_37276640_37276791 0.35 ENSG00000251838
 .
 447055
 0.01
chr9_1083553_1083729 0.35 DMRT2
 doublesex and mab-3 related transcription factor 2
 32027
 0.21
chr5_11961656_11961807 0.35 CTNND2
 catenin (cadherin-associated protein), delta 2
 57576
 0.18
chr9_16828717_16828972 0.35 BNC2
 basonuclin 2
 3442
 0.37
chr10_94632888_94633039 0.35 EXOC6
 exocyst complex component 6
 24686
 0.24
chr6_54405426_54405699 0.34 RP11-124I4.2
170793
 0.03
chr7_38209906_38210057 0.34 STARD3NL
 STARD3 N-terminal like
 7843
 0.32
chr15_95867203_95867354 0.34 ENSG00000222076
 .
 421755
 0.01
chr4_41122726_41122877 0.34 ENSG00000207198
 .
 6842
 0.23
chr2_73963170_73963321 0.33 TPRKB
 TP53RK binding protein
 1268
 0.45
chr7_27188769_27189232 0.33 HOXA-AS3
 HOXA cluster antisense RNA 3
 671
 0.36
chr5_75903118_75903290 0.33 CTD-2236F14.1
1591
 0.31
chr17_14210601_14210865 0.33 HS3ST3B1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
 6333
 0.28
chr3_189743937_189744088 0.32 ENSG00000265045
 .
 87711
 0.08
chr1_6452011_6452162 0.32 ACOT7
 acyl-CoA thioesterase 7
 1335
 0.27
chr1_170562641_170562838 0.32 RP11-576I22.2
60951
 0.12
chr1_215196200_215196360 0.32 KCNK2
 potassium channel, subfamily K, member 2
 17082
 0.31
chr2_36689023_36689174 0.32 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 51735
 0.14
chr6_131291045_131291463 0.32 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 369
 0.93
chr5_142136607_142136758 0.31 ARHGAP26
 Rho GTPase activating protein 26
 13267
 0.24
chr2_153252805_153253009 0.31 FMNL2
 formin-like 2
 61156
 0.15
chr2_235879385_235879568 0.31 SH3BP4
 SH3-domain binding protein 4
 7853
 0.34
chr9_138981896_138982047 0.31 NACC2
 NACC family member 2, BEN and BTB (POZ) domain containing
 5160
 0.22
chr3_44771799_44771953 0.31 ZNF501
 zinc finger protein 501
 788
 0.53
chr5_141703297_141704624 0.31 SPRY4
 sprouty homolog 4 (Drosophila)
 213
 0.88
chr6_13733598_13733910 0.31 RANBP9
 RAN binding protein 9
 21958
 0.19
chr3_79346408_79346559 0.31 ENSG00000265193
 .
 210554
 0.03
chr13_26477283_26477434 0.31 AL138815.2
 Uncharacterized protein
 24679
 0.17
chr9_128505902_128506053 0.31 PBX3
 pre-B-cell leukemia homeobox 3
 3647
 0.31
chr4_153194568_153194863 0.31 ENSG00000244544
 .
 9118
 0.23
chr4_157691238_157691428 0.30 RP11-154F14.2
71178
 0.11
chr1_66806954_66807105 0.30 PDE4B
 phosphodiesterase 4B, cAMP-specific
 9157
 0.31
chr1_100112572_100112850 0.30 PALMD
 palmdelphin
 962
 0.68
chr1_185606466_185606617 0.30 ENSG00000201596
 .
 3227
 0.29
chr1_100069801_100069952 0.30 PALMD
 palmdelphin
 41623
 0.19
chr1_155897053_155897204 0.30 ENSG00000252808
 .
 1251
 0.26
chr13_24121296_24121482 0.30 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 23120
 0.25
chr8_110632793_110632963 0.29 SYBU
 syntabulin (syntaxin-interacting)
 12574
 0.18
chr3_66514197_66514348 0.29 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
 37084
 0.22
chr12_114847651_114847803 0.29 TBX5-AS1
 TBX5 antisense RNA 1
 1168
 0.44
chr12_66590864_66591026 0.29 IRAK3
 interleukin-1 receptor-associated kinase 3
 7908
 0.16
chr7_143127648_143127805 0.29 TAS2R60
 taste receptor, type 2, member 60
 12820
 0.12
chr6_75940690_75940841 0.29 COX7A2
 cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
 12736
 0.2
chr7_43739481_43739640 0.29 COA1
 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
 29491
 0.18
chr7_118512519_118512670 0.29 ENSG00000222226
 .
 410041
 0.01
chr17_36861833_36863162 0.29 CTB-58E17.3
17
 0.9
chr3_190802793_190802944 0.28 OSTN
 osteocrin
 114162
 0.06
chr7_19144306_19144457 0.28 AC003986.6
7716
 0.17
chr12_78334931_78335200 0.28 NAV3
 neuron navigator 3
 24991
 0.28
chr1_215178346_215178497 0.28 KCNK2
 potassium channel, subfamily K, member 2
 777
 0.8
chr14_86002405_86002689 0.28 FLRT2
 fibronectin leucine rich transmembrane protein 2
 5975
 0.26
chr10_122451080_122451231 0.28 WDR11-AS1
 WDR11 antisense RNA 1
 85241
 0.09
chr11_91680280_91680431 0.28 FAT3
 FAT atypical cadherin 3
 404907
 0.01
chr11_6241000_6241151 0.28 C11orf42
 chromosome 11 open reading frame 42
 14279
 0.1
chr3_134050593_134051228 0.28 AMOTL2
 angiomotin like 2
 39844
 0.16
chrX_23919479_23919764 0.28 CXorf58
 chromosome X open reading frame 58
 6297
 0.2
chr21_43353842_43354056 0.28 C2CD2
 C2 calcium-dependent domain containing 2
 7150
 0.18
chr2_46933523_46933944 0.27 SOCS5
 suppressor of cytokine signaling 5
 7407
 0.22
chr7_151182359_151182552 0.27 ENSG00000241959
 .
 20431
 0.13
chr15_49083337_49083488 0.27 RP11-485O10.2
8025
 0.18
chr14_70485604_70486019 0.27 SLC8A3
 solute carrier family 8 (sodium/calcium exchanger), member 3
 61086
 0.14
chr18_30049396_30050442 0.27 GAREM
 GRB2 associated, regulator of MAPK1
 476
 0.87
chr11_12701583_12701887 0.27 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
 4685
 0.33
chr3_160192165_160192336 0.27 ENSG00000238427
 .
 2046
 0.26
chr10_54075051_54075395 0.27 DKK1
 dickkopf WNT signaling pathway inhibitor 1
 1167
 0.43
chr10_32201925_32202315 0.27 ARHGAP12
 Rho GTPase activating protein 12
 4318
 0.31
chr1_32042303_32042778 0.27 TINAGL1
 tubulointerstitial nephritis antigen-like 1
 401
 0.75
chr5_149310354_149310505 0.27 ENSG00000200334
 .
 9265
 0.15
chr19_15362877_15363312 0.27 EPHX3
 epoxide hydrolase 3
 18848
 0.15
chr2_145653557_145653708 0.27 ZEB2
 zinc finger E-box binding homeobox 2
 375011
 0.01
chr17_12947974_12948125 0.27 ELAC2
 elaC ribonuclease Z 2
 26545
 0.19
chr15_35601919_35602070 0.27 ENSG00000265102
 .
 62571
 0.15
chr3_105849899_105850071 0.27 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 261589
 0.02
chr5_146746092_146746307 0.27 DPYSL3
 dihydropyrimidinase-like 3
 34966
 0.18
chr10_90754998_90755312 0.27 ACTA2
 actin, alpha 2, smooth muscle, aorta
 4008
 0.17
chr3_93623597_93623748 0.27 PROS1
 protein S (alpha)
 53926
 0.11
chr3_45686186_45686439 0.27 LIMD1-AS1
 LIMD1 antisense RNA 1
 44062
 0.11
chr12_89210324_89210486 0.26 ENSG00000252850
 .
 234989
 0.02
chr16_69952007_69952311 0.26 WWP2
 WW domain containing E3 ubiquitin protein ligase 2
 6734
 0.17
chr2_151333058_151333209 0.26 RND3
 Rho family GTPase 3
 8763
 0.33
chr8_57086542_57086822 0.26 PLAG1
 pleiomorphic adenoma gene 1
 37156
 0.12
chr11_12065337_12065964 0.26 DKK3
 dickkopf WNT signaling pathway inhibitor 3
 34334
 0.19
chr6_108478555_108479189 0.26 OSTM1
 osteopetrosis associated transmembrane protein 1
 8172
 0.19
chr17_29335129_29336577 0.26 RP11-848P1.9
81
 0.95
chr9_530471_530746 0.26 RP11-31F19.1
16709
 0.13
chr2_157323820_157323971 0.26 GPD2
 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
 6189
 0.22
chr17_28037574_28037864 0.26 RP11-82O19.1
50402
 0.08
chr18_28619786_28619937 0.26 DSC3
 desmocollin 3
 2846
 0.25
chr5_33891538_33892159 0.26 ADAMTS12
 ADAM metallopeptidase with thrombospondin type 1 motif, 12
 198
 0.94
chr1_182338063_182338214 0.26 GLUL
 glutamate-ammonia ligase
 22401
 0.18
chr10_33230803_33231099 0.26 ITGB1
 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 5772
 0.31
chr4_123820303_123820454 0.26 NUDT6
 nudix (nucleoside diphosphate linked moiety X)-type motif 6
 14065
 0.17
chr2_171017422_171017573 0.26 MYO3B
 myosin IIIB
 17158
 0.23
chr11_61159610_61160825 0.26 TMEM216
 transmembrane protein 216
 352
 0.79
chr9_21329043_21329194 0.25 KLHL9
 kelch-like family member 9
 6122
 0.14
chr4_35309607_35309866 0.25 ENSG00000206665
 .
 187784
 0.03
chr5_36836552_36836703 0.25 NIPBL
 Nipped-B homolog (Drosophila)
 40234
 0.2
chr15_70316424_70316624 0.25 ENSG00000207965
 .
 55283
 0.15
chr3_4753555_4753835 0.25 ENSG00000239126
 .
 166691
 0.03
chr3_156800832_156800983 0.25 ENSG00000222499
 .
 65776
 0.09
chr19_43633813_43634101 0.25 PSG2
 pregnancy specific beta-1-glycoprotein 2
 47137
 0.12
chr10_123334259_123334410 0.25 FGFR2
 fibroblast growth factor receptor 2
 19009
 0.28
chr2_219582270_219582421 0.25 TTLL4
 tubulin tyrosine ligase-like family, member 4
 6628
 0.14
chr8_32441306_32441509 0.25 NRG1
 neuregulin 1
 21759
 0.28
chr2_100101443_100101594 0.25 REV1
 REV1, polymerase (DNA directed)
 4917
 0.24
chr10_27815365_27815516 0.25 RAB18
 RAB18, member RAS oncogene family
 21892
 0.24
chr9_21677527_21678485 0.25 ENSG00000244230
 .
 21307
 0.21
chr15_78171125_78171323 0.25 CSPG4P13
 chondroitin sulfate proteoglycan 4 pseudogene 13
 15802
 0.15
chr6_106897121_106897272 0.25 ENSG00000202386
 .
 60
 0.97
chr10_34809719_34809870 0.25 PARD3
 par-3 family cell polarity regulator
 94135
 0.09
chr12_13359480_13359859 0.25 EMP1
 epithelial membrane protein 1
 4776
 0.29
chr6_125932782_125933099 0.24 RP11-624M8.1
133234
 0.05
chr10_115143798_115143949 0.24 ENSG00000238380
 .
 30689
 0.24
chr2_228681607_228681918 0.24 CCL20
 chemokine (C-C motif) ligand 20
 3192
 0.28
chr11_19472113_19472264 0.24 ENSG00000200687
 .
 48660
 0.12
chr11_86516621_86516772 0.24 PRSS23
 protease, serine, 23
 5111
 0.32
chr1_59478905_59479109 0.24 JUN
 jun proto-oncogene
 229222
 0.02
chr20_18296318_18296469 0.24 RP4-568F9.3
638
 0.6
chr10_36184684_36184984 0.24 FZD8
 frizzled family receptor 8
 254472
 0.02
chr8_89311514_89311910 0.24 RP11-586K2.1
27353
 0.2
chr5_14448258_14448409 0.24 TRIO
 trio Rho guanine nucleotide exchange factor
 40224
 0.21
chr4_54926609_54926760 0.24 AC110792.1
 HCG2027126; Uncharacterized protein
 529
 0.75
chr13_110972233_110972468 0.24 COL4A2
 collagen, type IV, alpha 2
 12736
 0.21
chr4_173149760_173149911 0.24 GALNTL6
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
 176239
 0.04
chr8_108468386_108468792 0.24 ANGPT1
 angiopoietin 1
 38634
 0.23
chr12_122884260_122884886 0.24 CLIP1
 CAP-GLY domain containing linker protein 1
 12
 0.98
chr10_32215556_32215707 0.24 ARHGAP12
 Rho GTPase activating protein 12
 2097
 0.41
chr10_101432551_101432702 0.24 ENTPD7
 ectonucleoside triphosphate diphosphohydrolase 7
 13363
 0.14
chr1_193376231_193376382 0.24 B3GALT2
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
 220522
 0.02
chr6_41473165_41473397 0.24 RP11-328M4.2
40531
 0.13
chr6_157358181_157358332 0.24 RP1-137K2.2
82584
 0.1
chr3_191055905_191056279 0.24 UTS2B
 urotensin 2B
 7767
 0.23
chr2_145753937_145754126 0.24 ENSG00000253036
 .
 338607
 0.01
chr15_49726228_49726382 0.24 FGF7
 fibroblast growth factor 7
 10848
 0.24
chr13_49928496_49928647 0.23 CAB39L
 calcium binding protein 39-like
 3308
 0.31
chr3_137486919_137487668 0.23 SOX14
 SRY (sex determining region Y)-box 14
 3714
 0.37
chr20_46121886_46122388 0.23 ENSG00000201742
 .
 308
 0.88
chr2_46946794_46946945 0.23 SOCS5
 suppressor of cytokine signaling 5
 20543
 0.19
chr21_33317813_33317964 0.23 HUNK
 hormonally up-regulated Neu-associated kinase
 21024
 0.24
chr5_75902860_75903011 0.23 CTD-2236F14.1
1860
 0.28
chr5_158520357_158520666 0.23 EBF1
 early B-cell factor 1
 6190
 0.27
chr12_86229562_86230264 0.23 RASSF9
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
 435
 0.89
chr21_29172171_29172322 0.23 ADAMTS5
 ADAM metallopeptidase with thrombospondin type 1 motif, 5
 833414
 0.0
chr5_137358347_137358498 0.23 RP11-325L7.1
10041
 0.14
chr22_46422730_46422990 0.23 RP6-109B7.5
26113
 0.09
chr1_61561178_61561329 0.23 NFIA
 nuclear factor I/A
 7169
 0.21
chr16_11303461_11303612 0.23 RMI2
 RecQ mediated genome instability 2
 39970
 0.09
chr5_9533993_9534144 0.23 CTD-2201E9.2
10778
 0.18
chr12_115119174_115119325 0.23 TBX3
 T-box 3
 2146
 0.36
chr3_192634406_192635568 0.23 MB21D2
 Mab-21 domain containing 2
 963
 0.71
chr3_187984581_187985052 0.23 LPP
 LIM domain containing preferred translocation partner in lipoma
 27164
 0.24
chr6_148886821_148887018 0.23 ENSG00000223322
 .
 41543
 0.21
chr2_224703111_224703262 0.23 AP1S3
 adaptor-related protein complex 1, sigma 3 subunit
 442
 0.89
chr12_102093877_102094028 0.23 CHPT1
 choline phosphotransferase 1
 2502
 0.21
chr12_1428214_1428403 0.23 RP5-951N9.2
66691
 0.11
chr22_37583582_37583762 0.23 C1QTNF6
 C1q and tumor necrosis factor related protein 6
 654
 0.59
chrX_45365887_45366208 0.22 RP11-342D14.1
186344
 0.03
chr14_36786542_36786693 0.22 MBIP
 MAP3K12 binding inhibitory protein 1
 2459
 0.33
chr8_32137811_32137962 0.22 ENSG00000200246
 .
 23874
 0.22
chr7_130761600_130761776 0.22 LINC-PINT
 long intergenic non-protein coding RNA, p53 induced transcript
 11545
 0.21
chr4_17813550_17813701 0.22 NCAPG
 non-SMC condensin I complex, subunit G
 1100
 0.4
chr1_59246622_59247052 0.22 JUN
 jun proto-oncogene
 2948
 0.28
chr20_34459115_34459914 0.22 ENSG00000201221
 .
 16067
 0.13
chr7_34027760_34027911 0.22 BMPER
 BMP binding endothelial regulator
 82690
 0.11
chr3_7340877_7341028 0.22 GRM7
 glutamate receptor, metabotropic 7
 103785
 0.08

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR2E1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.5 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.1 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.2 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.1 0.2 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:0008218 bioluminescence(GO:0008218)
0.1 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.2 GO:0010159 specification of organ position(GO:0010159)
0.0 0.4 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.0 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.4 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0031223 auditory behavior(GO:0031223)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0060044 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.2 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0045978 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.2 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.4 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.2 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.1 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.1 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.0 GO:0032278 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.0 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0010664 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.1 GO:0050922 negative regulation of chemotaxis(GO:0050922)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.1 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.0 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.0 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.0 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0071456 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.0 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.1 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.0 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.1 GO:0007379 segment specification(GO:0007379)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:1902339 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0014034 neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.0 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.0 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0046636 negative regulation of alpha-beta T cell activation(GO:0046636)
0.0 0.0 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0006067 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.0 GO:0001710 mesodermal cell fate commitment(GO:0001710)
0.0 0.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.0 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.0 GO:0007619 courtship behavior(GO:0007619)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0043205 fibril(GO:0043205)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis