Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR2E3

Z-value: 1.94

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Transcription factors associated with NR2E3

Gene Symbol Gene ID Gene Info
NR2E3
ENSG00000031544.10 NR2E3

Activity of the NR2E3 motif across conditions

Conditions sorted by the z-value of the NR2E3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_139269163_139269314 0.54 CLEC2L
 C-type lectin domain family 2, member L
 60410
 0.13
chr11_46004734_46004939 0.52 PHF21A
 PHD finger protein 21A
 37416
 0.13
chr14_100345979_100346191 0.50 EML1
 echinoderm microtubule associated protein like 1
 14139
 0.22
chr5_176980162_176981368 0.45 FAM193B
 family with sequence similarity 193, member B
 2
 0.96
chr7_76435318_76435469 0.44 ENSG00000231183
 .
 105029
 0.06
chr5_148786834_148787025 0.44 ENSG00000208035
 .
 21552
 0.11
chr5_9543546_9543700 0.43 SEMA5A
 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
 2564
 0.27
chr3_195310822_195311023 0.43 APOD
 apolipoprotein D
 111
 0.96
chr2_239696603_239696754 0.43 TWIST2
 twist family bHLH transcription factor 2
 59995
 0.14
chr2_197615974_197616125 0.43 GTF3C3
 general transcription factor IIIC, polypeptide 3, 102kDa
 25120
 0.17
chr20_8113545_8114201 0.42 PLCB1
 phospholipase C, beta 1 (phosphoinositide-specific)
 571
 0.84
chr3_73671180_73671369 0.42 PDZRN3-AS1
 PDZRN3 antisense RNA 1
 410
 0.85
chr18_52985124_52985322 0.40 TCF4
 transcription factor 4
 3994
 0.34
chr2_74804249_74804525 0.40 LOXL3
 lysyl oxidase-like 3
 21570
 0.09
chr3_114169976_114170457 0.40 ZBTB20
 zinc finger and BTB domain containing 20
 3314
 0.33
chr13_74339708_74339938 0.39 KLF12
 Kruppel-like factor 12
 229363
 0.02
chr7_15718984_15719135 0.39 MEOX2
 mesenchyme homeobox 2
 7378
 0.25
chr7_19152487_19152712 0.39 AC003986.6
502
 0.75
chr5_134689632_134689991 0.39 C5orf66
 chromosome 5 open reading frame 66
 16182
 0.18
chr21_17566581_17566826 0.39 ENSG00000201025
 .
 90386
 0.1
chr10_111765795_111766267 0.39 ADD3
 adducin 3 (gamma)
 469
 0.79
chr2_102090260_102091186 0.39 RFX8
 RFX family member 8, lacking RFX DNA binding domain
 14
 0.99
chr11_92117878_92118174 0.38 RP11-675M1.2
23316
 0.23
chr16_65078597_65078898 0.38 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 14834
 0.32
chr9_113819053_113819204 0.38 LPAR1
 lysophosphatidic acid receptor 1
 18147
 0.23
chr1_46596937_46597125 0.37 PIK3R3
 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
 1257
 0.38
chr18_70210992_70211675 0.37 CBLN2
 cerebellin 2 precursor
 441
 0.91
chr2_38373660_38374056 0.37 ENSG00000199603
 .
 699
 0.72
chr10_15367555_15367706 0.37 FAM171A1
 family with sequence similarity 171, member A1
 45428
 0.17
chr10_30346435_30346778 0.36 KIAA1462
 KIAA1462
 1847
 0.5
chr6_148830339_148830689 0.36 ENSG00000223322
 .
 14862
 0.29
chr1_67001631_67001824 0.36 SGIP1
 SH3-domain GRB2-like (endophilin) interacting protein 1
 1762
 0.47
chr12_75877051_75877218 0.36 GLIPR1
 GLI pathogenesis-related 1
 2150
 0.29
chr20_34327959_34328110 0.35 RBM39
 RNA binding motif protein 39
 725
 0.54
chr10_60778966_60779198 0.35 ENSG00000252076
 .
 150138
 0.04
chr21_28211571_28211722 0.35 ADAMTS1
 ADAM metallopeptidase with thrombospondin type 1 motif, 1
 3691
 0.31
chr13_27262543_27262694 0.35 WASF3-AS1
 WASF3 antisense RNA 1
 47117
 0.17
chr4_152146952_152147499 0.35 SH3D19
 SH3 domain containing 19
 7
 0.98
chr1_168440138_168440500 0.35 XCL2
 chemokine (C motif) ligand 2
 72916
 0.1
chr12_16505389_16505562 0.35 MGST1
 microsomal glutathione S-transferase 1
 876
 0.7
chr1_78961937_78962088 0.34 PTGFR
 prostaglandin F receptor (FP)
 5255
 0.31
chr4_163085753_163086130 0.34 FSTL5
 follistatin-like 5
 754
 0.8
chr6_148593126_148593282 0.34 SASH1
 SAM and SH3 domain containing 1
 236
 0.93
chr12_88974186_88974700 0.34 KITLG
 KIT ligand
 185
 0.91
chr9_18476160_18476529 0.34 ADAMTSL1
 ADAMTS-like 1
 2113
 0.45
chr10_61926811_61926972 0.33 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
 237
 0.96
chr6_44509899_44510345 0.33 ENSG00000266619
 .
 106744
 0.06
chr1_226851993_226852200 0.33 ITPKB-AS1
 ITPKB antisense RNA 1
 4502
 0.23
chr15_74609980_74610180 0.33 CCDC33
 coiled-coil domain containing 33
 820
 0.56
chr7_28205881_28206089 0.33 JAZF1-AS1
 JAZF1 antisense RNA 1
 13956
 0.2
chr9_136423526_136423721 0.33 FAM163B
 family with sequence similarity 163, member B
 21745
 0.12
chr18_52985449_52985614 0.33 TCF4
 transcription factor 4
 3686
 0.35
chr6_74226740_74227178 0.33 EEF1A1
 eukaryotic translation elongation factor 1 alpha 1
 3782
 0.14
chr6_136174272_136174471 0.33 PDE7B
 phosphodiesterase 7B
 1537
 0.51
chr6_143014732_143015018 0.33 RP1-67K17.3
54705
 0.17
chr2_77707642_77707793 0.32 LRRTM4
 leucine rich repeat transmembrane neuronal 4
 41619
 0.23
chr20_4906633_4907049 0.32 SLC23A2
 solute carrier family 23 (ascorbic acid transporter), member 2
 26548
 0.16
chr1_240739354_240740022 0.32 RP11-467I20.6
14360
 0.2
chr1_224805648_224805799 0.32 CNIH3
 cornichon family AMPA receptor auxiliary protein 3
 1728
 0.32
chr5_163284242_163284393 0.31 ENSG00000251998
 .
 61146
 0.16
chr1_246948051_246948632 0.31 ENSG00000227953
 .
 5585
 0.17
chr15_96880594_96880802 0.31 ENSG00000222651
 .
 4208
 0.18
chr15_96886504_96886655 0.31 ENSG00000222651
 .
 10089
 0.16
chr5_148787363_148787711 0.31 ENSG00000208035
 .
 20944
 0.11
chr16_17453037_17453188 0.31 XYLT1
 xylosyltransferase I
 111626
 0.08
chr3_57004581_57004732 0.31 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
 6747
 0.24
chr6_143897172_143897323 0.31 RP11-436I24.1
14079
 0.19
chr6_144627329_144627480 0.31 UTRN
 utrophin
 14439
 0.24
chr5_14441902_14442179 0.31 TRIO
 trio Rho guanine nucleotide exchange factor
 46517
 0.19
chr10_33547914_33548065 0.30 NRP1
 neuropilin 1
 4643
 0.26
chr2_159698320_159698471 0.30 OR7E89P
 olfactory receptor, family 7, subfamily E, member 89 pseudogene
 11872
 0.19
chr3_127897617_127897768 0.30 RUVBL1
 RuvB-like AAA ATPase 1
 24935
 0.16
chr4_88765324_88765486 0.30 MEPE
 matrix extracellular phosphoglycoprotein
 11266
 0.2
chr4_41178199_41178352 0.30 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 38200
 0.15
chr13_76213551_76213793 0.30 LMO7
 LIM domain 7
 3213
 0.22
chr7_120629708_120629973 0.30 CPED1
 cadherin-like and PC-esterase domain containing 1
 164
 0.96
chr12_14990048_14990229 0.30 RP11-233G1.4
3888
 0.14
chr8_133688256_133688407 0.29 LRRC6
 leucine rich repeat containing 6
 493
 0.81
chr9_2054192_2054426 0.29 RP11-264I13.2
8286
 0.25
chr5_96503337_96503488 0.29 RIOK2
 RIO kinase 2
 11
 0.97
chr14_69511912_69512063 0.29 ACTN1-AS1
 ACTN1 antisense RNA 1
 65229
 0.1
chr11_113114508_113114659 0.29 NCAM1-AS1
 NCAM1 antisense RNA1
 29945
 0.15
chr17_64187141_64188685 0.29 CEP112
 centrosomal protein 112kDa
 60
 0.98
chr2_175671888_175672200 0.29 CHN1
 chimerin 1
 39089
 0.16
chr21_38731087_38731365 0.29 AP001437.1
7008
 0.21
chr2_66670252_66670507 0.29 MEIS1
 Meis homeobox 1
 282
 0.85
chr18_56244732_56244930 0.29 RP11-126O1.2
20529
 0.14
chr2_239553535_239553686 0.29 TWIST2
 twist family bHLH transcription factor 2
 203063
 0.02
chr15_57513206_57513402 0.29 TCF12
 transcription factor 12
 1640
 0.49
chr4_139935567_139935733 0.29 CCRN4L
 CCR4 carbon catabolite repression 4-like (S. cerevisiae)
 1293
 0.33
chr18_72662566_72662717 0.29 ZADH2
 zinc binding alcohol dehydrogenase domain containing 2
 254827
 0.02
chr19_57182553_57183430 0.28 ZNF835
 zinc finger protein 835
 137
 0.95
chr5_92921648_92921875 0.28 ENSG00000237187
 .
 407
 0.85
chr20_32597295_32597446 0.28 RALY
 RALY heterogeneous nuclear ribonucleoprotein
 15611
 0.19
chr1_83809421_83809572 0.28 ENSG00000223231
 .
 450064
 0.01
chr4_86781115_86781329 0.28 ARHGAP24
 Rho GTPase activating protein 24
 32176
 0.2
chr4_86700210_86700446 0.28 ARHGAP24
 Rho GTPase activating protein 24
 469
 0.88
chr3_132293024_132293175 0.28 ACKR4
 atypical chemokine receptor 4
 22982
 0.22
chr19_11892071_11892222 0.28 ZNF441
 zinc finger protein 441
 14239
 0.11
chr3_71300419_71300570 0.28 FOXP1
 forkhead box P1
 6178
 0.29
chr5_94128895_94129046 0.28 CTC-484P3.3
4476
 0.33
chr6_141785028_141785179 0.28 ENSG00000222764
 .
 22446
 0.29
chr19_47606103_47606254 0.28 SAE1
 SUMO1 activating enzyme subunit 1
 10353
 0.14
chr5_120535278_120535429 0.28 ENSG00000222609
 .
 488818
 0.01
chr2_183413035_183413186 0.28 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
 25645
 0.26
chr4_17815758_17815964 0.27 NCAPG
 non-SMC condensin I complex, subunit G
 3336
 0.24
chr8_103136777_103137074 0.27 NCALD
 neurocalcin delta
 117
 0.91
chr16_576320_577633 0.27 CAPN15
 calpain 15
 741
 0.43
chr2_87551749_87551924 0.27 IGKV3OR2-268
 immunoglobulin kappa variable 3/OR2-268 (non-functional)
 13798
 0.29
chr12_69869461_69869623 0.27 FRS2
 fibroblast growth factor receptor substrate 2
 5328
 0.25
chr15_49731792_49731943 0.27 FGF7
 fibroblast growth factor 7
 16410
 0.23
chr6_35017519_35017670 0.27 TCP11
 t-complex 11, testis-specific
 71228
 0.1
chr16_72089790_72089941 0.27 HP
 haptoglobin
 195
 0.89
chr2_238321930_238322164 0.27 COL6A3
 collagen, type VI, alpha 3
 744
 0.69
chr16_88981438_88981589 0.27 CBFA2T3
 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
 12590
 0.11
chr10_116063923_116064706 0.27 VWA2
 von Willebrand factor A domain containing 2
 65225
 0.11
chr20_10701589_10701740 0.27 JAG1
 jagged 1
 46970
 0.17
chr8_37124215_37124389 0.27 RP11-150O12.6
250237
 0.02
chrX_8899754_8899905 0.27 FAM9B
 family with sequence similarity 9, member B
 101287
 0.08
chr3_12477991_12478218 0.27 TSEN2
 TSEN2 tRNA splicing endonuclease subunit
 47827
 0.12
chr1_88150758_88150976 0.27 ENSG00000199318
 .
 231811
 0.02
chr22_29877205_29877409 0.27 NEFH
 neurofilament, heavy polypeptide
 1088
 0.41
chr12_16008998_16009198 0.27 EPS8
 epidermal growth factor receptor pathway substrate 8
 26165
 0.19
chr11_104763545_104763789 0.27 CASP12
 caspase 12 (gene/pseudogene)
 5474
 0.23
chr8_38561274_38561447 0.26 TACC1
 transforming, acidic coiled-coil containing protein 1
 24344
 0.19
chr15_66996459_66997031 0.26 SMAD6
 SMAD family member 6
 2071
 0.4
chr16_14280583_14281066 0.26 MKL2
 MKL/myocardin-like 2
 52
 0.98
chr19_11942280_11942431 0.26 ZNF440
 zinc finger protein 440
 1554
 0.27
chr5_39423780_39424080 0.26 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 1040
 0.66
chr14_45711437_45711895 0.26 MIS18BP1
 MIS18 binding protein 1
 10714
 0.2
chr3_21489168_21489319 0.26 ENSG00000252306
 .
 59134
 0.15
chr1_83974538_83974802 0.26 ENSG00000223231
 .
 284890
 0.01
chrX_114468679_114469096 0.26 LRCH2
 leucine-rich repeats and calponin homology (CH) domain containing 2
 252
 0.93
chr1_162469519_162469670 0.26 UHMK1
 U2AF homology motif (UHM) kinase 1
 1961
 0.33
chr4_114063101_114063433 0.26 ANK2
 ankyrin 2, neuronal
 3521
 0.33
chr6_148845958_148846135 0.26 ENSG00000223322
 .
 670
 0.82
chr7_102553717_102554092 0.26 LRRC17
 leucine rich repeat containing 17
 452
 0.83
chr5_87798376_87798680 0.26 TMEM161B-AS1
 TMEM161B antisense RNA 1
 76016
 0.11
chr1_90464057_90464208 0.26 ZNF326
 zinc finger protein 326
 3405
 0.29
chr8_125979576_125979727 0.26 ZNF572
 zinc finger protein 572
 5889
 0.2
chr8_97111651_97111825 0.26 GDF6
 growth differentiation factor 6
 61282
 0.14
chr20_290796_291047 0.26 ZCCHC3
 zinc finger, CCHC domain containing 3
 13184
 0.11
chr10_125650568_125650719 0.26 CPXM2
 carboxypeptidase X (M14 family), member 2
 687
 0.72
chr1_160635203_160635434 0.26 RP11-404F10.2
5250
 0.17
chr12_20597811_20597962 0.26 RP11-284H19.1
74690
 0.11
chr11_27717169_27717347 0.26 BDNF
 brain-derived neurotrophic factor
 3956
 0.29
chr8_116676800_116677144 0.26 TRPS1
 trichorhinophalangeal syndrome I
 3067
 0.41
chr2_204975771_204975922 0.26 ICOS
 inducible T-cell co-stimulator
 174343
 0.03
chr11_130393001_130393152 0.25 ADAMTS15
 ADAM metallopeptidase with thrombospondin type 1 motif, 15
 74207
 0.11
chr15_74724525_74724676 0.25 SEMA7A
 semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
 1401
 0.35
chr12_53684565_53684716 0.25 PFDN5
 prefoldin subunit 5
 4435
 0.11
chr8_23618854_23619099 0.25 ENSG00000216123
 .
 7182
 0.19
chr9_117762726_117762877 0.25 TNC
 tenascin C
 64390
 0.12
chr16_50091812_50091963 0.25 HEATR3
 HEAT repeat containing 3
 7965
 0.16
chr11_27721206_27721474 0.25 BDNF
 brain-derived neurotrophic factor
 126
 0.97
chrX_130868362_130868725 0.25 OR13H1
 olfactory receptor, family 13, subfamily H, member 1
 190593
 0.03
chr2_216288358_216288696 0.25 FN1
 fibronectin 1
 12263
 0.21
chr18_10059803_10059983 0.25 ENSG00000263630
 .
 54699
 0.15
chr3_11494611_11494762 0.25 ATG7
 autophagy related 7
 88553
 0.09
chr14_22466955_22467106 0.25 ENSG00000238634
 .
 143857
 0.04
chr5_176498779_176498948 0.25 FGFR4
 fibroblast growth factor receptor 4
 15024
 0.16
chr10_112466206_112466357 0.25 ENSG00000252036
 .
 49933
 0.1
chr8_101696697_101696848 0.25 ENSG00000252764
 .
 1056
 0.44
chr3_157160828_157160979 0.25 PTX3
 pentraxin 3, long
 6325
 0.27
chr8_93074610_93074813 0.25 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 480
 0.89
chr17_38604609_38604760 0.25 IGFBP4
 insulin-like growth factor binding protein 4
 4971
 0.15
chr1_215256963_215257162 0.25 KCNK2
 potassium channel, subfamily K, member 2
 202
 0.97
chr6_151563077_151563228 0.25 AKAP12
 A kinase (PRKA) anchor protein 12
 1643
 0.31
chr6_35184176_35184465 0.25 SCUBE3
 signal peptide, CUB domain, EGF-like 3
 2124
 0.33
chr10_31039823_31039974 0.25 SVILP1
 supervillin pseudogene 1
 55048
 0.14
chr5_75689119_75689270 0.25 IQGAP2
 IQ motif containing GTPase activating protein 2
 9880
 0.28
chr13_36274231_36274441 0.25 NBEA
 neurobeachin
 107193
 0.07
chr17_54347625_54347776 0.25 ANKFN1
 ankyrin-repeat and fibronectin type III domain containing 1
 96164
 0.09
chr7_33732550_33732701 0.25 RP11-89N17.1
 HCG1643653; Uncharacterized protein
 32968
 0.2
chr1_234879504_234879854 0.25 ENSG00000201638
 .
 94041
 0.08
chrX_47272886_47273037 0.25 ENSG00000221459
 .
 24913
 0.14
chr10_111752488_111752745 0.25 ENSG00000263706
 .
 11396
 0.19
chr13_114883822_114884057 0.25 RASA3-IT1
 RASA3 intronic transcript 1 (non-protein coding)
 9644
 0.22
chr2_127951864_127952015 0.25 CYP27C1
 cytochrome P450, family 27, subfamily C, polypeptide 1
 11404
 0.24
chr14_73203955_73204106 0.24 ENSG00000206751
 .
 116009
 0.06
chr12_9913975_9914126 0.24 CD69
 CD69 molecule
 553
 0.73
chr6_39850177_39850421 0.24 RP11-61I13.3
4045
 0.27
chr15_33356537_33356688 0.24 FMN1
 formin 1
 3473
 0.35
chr5_122823186_122823354 0.24 ENSG00000202105
 .
 22961
 0.2
chr3_144309568_144309751 0.24 ENSG00000222778
 .
 403797
 0.01
chr7_111079218_111079369 0.24 IMMP2L
 IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
 46322
 0.2
chr15_67373894_67374045 0.24 SMAD3
 SMAD family member 3
 15786
 0.25
chr2_8055962_8056119 0.24 ENSG00000221255
 .
 339068
 0.01
chrX_49122410_49122561 0.24 FOXP3
 forkhead box P3
 1197
 0.27
chr1_98854236_98854448 0.24 ENSG00000221777
 .
 15401
 0.31
chr6_131382789_131382971 0.24 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 836
 0.75
chr7_42645149_42645379 0.24 C7orf25
 chromosome 7 open reading frame 25
 306245
 0.01
chr9_113663364_113663515 0.24 ENSG00000206923
 .
 2178
 0.37
chr11_66384139_66385370 0.24 RBM14
 RNA binding motif protein 14
 568
 0.3
chr7_19154054_19154205 0.24 AC003986.6
2032
 0.25
chr1_219116097_219116279 0.24 LYPLAL1
 lysophospholipase-like 1
 230998
 0.02
chr2_207938936_207939147 0.24 ENSG00000253008
 .
 35756
 0.16
chr1_161187488_161187639 0.24 FCER1G
 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
 2476
 0.1
chr5_88175709_88175899 0.24 MEF2C
 myocyte enhancer factor 2C
 2010
 0.37
chr1_54199074_54199253 0.24 GLIS1
 GLIS family zinc finger 1
 714
 0.69

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR2E3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.6 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.1 0.5 GO:0051299 centrosome separation(GO:0051299)
0.1 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.3 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.3 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.2 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.2 GO:0050955 thermoception(GO:0050955)
0.1 0.2 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.2 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.3 GO:0032352 positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.1 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.1 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.2 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.2 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.1 0.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 0.2 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.5 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.2 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0046958 nonassociative learning(GO:0046958)
0.0 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.3 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.2 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0070828 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.2 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.3 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.1 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.2 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.2 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.2 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.1 GO:0032730 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0046645 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588) regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300) diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.2 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.2 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.0 0.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.2 GO:0051322 anaphase(GO:0051322)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.0 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.1 GO:0032823 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.1 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0010042 response to manganese ion(GO:0010042)
0.0 0.0 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.0 GO:0010875 positive regulation of cholesterol efflux(GO:0010875)
0.0 0.0 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0050702 interleukin-1 beta secretion(GO:0050702)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0032372 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0 0.0 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.0 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.0 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.0 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.0 GO:0015911 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) plasma membrane long-chain fatty acid transport(GO:0015911)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.2 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.3 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.0 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0002855 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.0 GO:0002227 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0 0.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0031427 response to methotrexate(GO:0031427)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0055094 response to lipoprotein particle(GO:0055094)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0043102 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0046325 negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0 0.2 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.0 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0042891 antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.0 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.0 0.0 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0035751 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.0 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.0 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.0 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.0 GO:0032651 regulation of interleukin-1 beta production(GO:0032651)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.3 GO:0051318 G1 phase(GO:0051318)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.4 GO:0060606 neural tube closure(GO:0001843) primary neural tube formation(GO:0014020) tube closure(GO:0060606)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.0 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0042308 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.0 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.0 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0014823 response to activity(GO:0014823)
0.0 0.0 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.0 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.0 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.1 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0003309 type B pancreatic cell differentiation(GO:0003309)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.1 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.0 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0015893 drug transport(GO:0015893)
0.0 0.0 GO:0007080 mitotic metaphase plate congression(GO:0007080)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0000791 euchromatin(GO:0000791)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.6 GO:0005814 centriole(GO:0005814)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.4 GO:0005884 actin filament(GO:0005884)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.0 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.3 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.0 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.0 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0001527 microfibril(GO:0001527)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0009374 biotin binding(GO:0009374)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.3 GO:0043176 amine binding(GO:0043176)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0070061 fructose binding(GO:0070061)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.7 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.0 GO:0032356 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.0 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.0 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.0 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 0.1 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.0 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.0 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.0 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.0 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)