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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR5A2

Z-value: 1.01

Motif logo

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Transcription factors associated with NR5A2

Gene Symbol Gene ID Gene Info
ENSG00000116833.9 NR5A2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NR5A2chr1_200003972_20000442171850.179076-0.599.2e-02Click!
NR5A2chr1_200011361_2000115122810.903812-0.571.1e-01Click!
NR5A2chr1_200005044_20000519565980.182058-0.472.0e-01Click!
NR5A2chr1_200011740_200011891980.966964-0.442.3e-01Click!
NR5A2chr1_200004550_20000473670740.179701-0.393.0e-01Click!

Activity of the NR5A2 motif across conditions

Conditions sorted by the z-value of the NR5A2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_56408975_56409725 0.98 MIR142
microRNA 142
519
0.63
chr11_65184608_65185159 0.94 ENSG00000245532
.
27046
0.09
chr14_93118654_93119048 0.78 RIN3
Ras and Rab interactor 3
5
0.99
chr9_95822109_95822464 0.77 SUSD3
sushi domain containing 3
1225
0.45
chr1_202130035_202130186 0.73 PTPN7
protein tyrosine phosphatase, non-receptor type 7
338
0.84
chr16_28996496_28996848 0.71 LAT
linker for activation of T cells
11
0.94
chr17_263385_263906 0.71 AC108004.3

169
0.93
chr16_88767040_88767399 0.65 RNF166
ring finger protein 166
208
0.83
chr17_72733506_72734386 0.61 RAB37
RAB37, member RAS oncogene family
575
0.59
chr5_175085682_175085863 0.55 HRH2
histamine receptor H2
739
0.7
chr9_117691730_117691942 0.54 TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
861
0.73
chr2_113933581_113933732 0.52 AC016683.5

719
0.56
chr2_233925207_233925694 0.51 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
261
0.92
chr11_118094529_118095128 0.50 AMICA1
adhesion molecule, interacts with CXADR antigen 1
26
0.97
chr16_28997019_28997515 0.50 LAT
linker for activation of T cells
266
0.8
chr1_160680341_160680580 0.49 CD48
CD48 molecule
1133
0.45
chr11_1874347_1875032 0.48 LSP1
lymphocyte-specific protein 1
489
0.65
chr11_121324494_121324645 0.47 RP11-730K11.1

847
0.59
chr19_17958305_17958511 0.47 JAK3
Janus kinase 3
418
0.74
chr1_39681454_39681741 0.46 RP11-416A14.1

9413
0.17
chr14_76009252_76009829 0.46 BATF
basic leucine zipper transcription factor, ATF-like
20637
0.15
chr11_64511299_64511931 0.45 RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
2
0.96
chr7_37486894_37487045 0.45 ELMO1
engulfment and cell motility 1
1584
0.4
chr7_50348449_50348781 0.44 IKZF1
IKAROS family zinc finger 1 (Ikaros)
297
0.94
chr17_29646389_29646953 0.43 CTD-2370N5.3

822
0.44
chr20_35272938_35273145 0.43 SLA2
Src-like-adaptor 2
1243
0.37
chr12_51712894_51713057 0.42 BIN2
bridging integrator 2
4924
0.17
chr5_176785343_176785607 0.42 RGS14
regulator of G-protein signaling 14
637
0.54
chr1_6087801_6087952 0.41 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
519
0.77
chr13_31311278_31311505 0.41 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
1746
0.48
chr19_14551433_14551660 0.41 PKN1
protein kinase N1
474
0.7
chr17_73840046_73840332 0.40 UNC13D
unc-13 homolog D (C. elegans)
226
0.84
chr19_1068460_1068611 0.40 HMHA1
histocompatibility (minor) HA-1
1038
0.32
chr21_36399790_36399994 0.40 RUNX1
runt-related transcription factor 1
21570
0.29
chr12_15113209_15113383 0.40 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
904
0.55
chr15_75082239_75082553 0.40 ENSG00000264386
.
1298
0.27
chr17_4389201_4389708 0.39 RP13-580F15.2

194
0.92
chr10_50395214_50395459 0.39 C10orf128
chromosome 10 open reading frame 128
1021
0.55
chr17_76255043_76255413 0.38 TMEM235
transmembrane protein 235
27106
0.12
chr19_54880943_54881230 0.38 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
972
0.39
chr2_47406474_47406729 0.38 CALM2
calmodulin 2 (phosphorylase kinase, delta)
2861
0.29
chr3_128835318_128835661 0.38 RAB43
RAB43, member RAS oncogene family
5135
0.13
chr19_8641491_8641716 0.37 MYO1F
myosin IF
719
0.54
chr8_134085908_134086059 0.37 SLA
Src-like-adaptor
13380
0.24
chr7_38398847_38399253 0.37 AMPH
amphiphysin
103663
0.08
chr19_39108076_39108634 0.37 MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
209
0.87
chr11_117860130_117860281 0.37 IL10RA
interleukin 10 receptor, alpha
3096
0.25
chr8_19495360_19495521 0.37 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
35434
0.23
chr8_125487510_125488222 0.36 RNF139
ring finger protein 139
887
0.55
chr9_134147000_134147362 0.36 FAM78A
family with sequence similarity 78, member A
1271
0.44
chr1_198617358_198617617 0.36 PTPRC
protein tyrosine phosphatase, receptor type, C
9195
0.24
chr3_113251981_113252391 0.36 SIDT1
SID1 transmembrane family, member 1
968
0.54
chr6_27106968_27108062 0.36 HIST1H4I
histone cluster 1, H4i
439
0.71
chr19_13044658_13044845 0.35 FARSA
phenylalanyl-tRNA synthetase, alpha subunit
100
0.89
chr1_225654970_225655492 0.35 RP11-496N12.6

2186
0.34
chr5_75700240_75700391 0.35 IQGAP2
IQ motif containing GTPase activating protein 2
66
0.98
chr1_112019023_112019174 0.35 C1orf162
chromosome 1 open reading frame 162
2607
0.15
chr2_237445797_237446029 0.35 IQCA1
IQ motif containing with AAA domain 1
29728
0.19
chr11_3855665_3855911 0.35 RHOG
ras homolog family member G
3309
0.13
chr6_33043813_33044241 0.35 HLA-DPB1
major histocompatibility complex, class II, DP beta 1
284
0.84
chr17_76755792_76756034 0.34 CYTH1
cytohesin 1
22441
0.17
chr1_167602601_167602772 0.34 RP3-455J7.4

2775
0.25
chr7_30199656_30199839 0.34 AC007036.5

2600
0.25
chr20_55967269_55967568 0.33 RBM38
RNA binding motif protein 38
132
0.89
chr1_32718292_32718517 0.33 LCK
lymphocyte-specific protein tyrosine kinase
1529
0.2
chr4_2802491_2802761 0.33 SH3BP2
SH3-domain binding protein 2
1901
0.35
chr2_237446959_237447193 0.33 ACKR3
atypical chemokine receptor 3
29354
0.19
chr16_3630185_3630336 0.32 NLRC3
NLR family, CARD domain containing 3
2859
0.2
chr8_21769513_21769765 0.32 DOK2
docking protein 2, 56kDa
1535
0.4
chr11_61786575_61786726 0.32 AP003733.1
Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
51197
0.09
chr11_47399235_47399544 0.32 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
553
0.59
chr20_62271866_62272113 0.32 STMN3
stathmin-like 3
12130
0.09
chr1_161038546_161039545 0.32 ARHGAP30
Rho GTPase activating protein 30
411
0.65
chr1_26316819_26316970 0.31 PAFAH2
platelet-activating factor acetylhydrolase 2, 40kDa
7218
0.1
chr12_58134671_58134822 0.31 AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
1194
0.21
chr16_23837804_23837955 0.31 PRKCB
protein kinase C, beta
9443
0.23
chr4_143298422_143298705 0.31 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
53849
0.19
chr2_240187102_240187645 0.31 ENSG00000265215
.
39784
0.13
chr7_150415780_150415950 0.31 GIMAP1
GTPase, IMAP family member 1
2220
0.26
chr20_328398_328906 0.31 RP5-1103G7.4

216
0.57
chr4_6928559_6928859 0.31 TBC1D14
TBC1 domain family, member 14
16734
0.16
chr19_49362364_49362642 0.31 PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
128
0.91
chr22_31685093_31685245 0.30 PIK3IP1
phosphoinositide-3-kinase interacting protein 1
3212
0.14
chr1_117299309_117299473 0.30 CD2
CD2 molecule
2302
0.33
chr7_45016674_45016991 0.30 MYO1G
myosin IG
1865
0.25
chr6_13274566_13274804 0.30 RP1-257A7.4

394
0.82
chr14_100532787_100533367 0.30 EVL
Enah/Vasp-like
303
0.88
chr19_17515989_17516450 0.30 BST2
bone marrow stromal cell antigen 2
238
0.54
chr13_46745397_46745548 0.30 ENSG00000240767
.
1589
0.32
chr6_41650642_41650943 0.30 AL035588.1

3172
0.18
chr15_52513775_52514010 0.30 GNB5
guanine nucleotide binding protein (G protein), beta 5
30326
0.14
chr5_75699014_75699893 0.30 IQGAP2
IQ motif containing GTPase activating protein 2
304
0.94
chr8_126517755_126517906 0.30 ENSG00000266452
.
61023
0.14
chr19_42705324_42705475 0.30 ENSG00000265122
.
8169
0.09
chr10_22622036_22622322 0.30 BMI1
BMI1 polycomb ring finger oncogene
6731
0.15
chr17_56416209_56416360 0.30 BZRAP1-AS1
BZRAP1 antisense RNA 1
1565
0.24
chr7_38389675_38390189 0.29 AMPH
amphiphysin
112781
0.07
chr15_34627792_34628213 0.29 SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
1043
0.38
chr19_43033217_43033368 0.29 CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
631
0.71
chr22_50752772_50753385 0.29 XX-C283C717.1

18
0.95
chr19_3178230_3178381 0.29 S1PR4
sphingosine-1-phosphate receptor 4
431
0.74
chr2_204804413_204804564 0.29 ICOS
inducible T-cell co-stimulator
2985
0.36
chr8_144273081_144273547 0.29 GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
21754
0.13
chr10_70850849_70851349 0.29 SRGN
serglycin
3225
0.25
chr13_49832065_49832609 0.29 CDADC1
cytidine and dCMP deaminase domain containing 1
10153
0.23
chr9_129233663_129234100 0.29 ENSG00000252985
.
44709
0.13
chr17_3866518_3867344 0.29 ATP2A3
ATPase, Ca++ transporting, ubiquitous
654
0.71
chr15_101782791_101782964 0.29 CHSY1
chondroitin sulfate synthase 1
9260
0.18
chr9_42914298_42914449 0.28 AC129778.2

55288
0.15
chr6_32159695_32160229 0.28 GPSM3
G-protein signaling modulator 3
683
0.42
chr19_55850633_55850856 0.28 SUV420H2
suppressor of variegation 4-20 homolog 2 (Drosophila)
477
0.39
chr11_14665333_14666638 0.28 PDE3B
phosphodiesterase 3B, cGMP-inhibited
608
0.56
chr14_22946001_22946152 0.28 TRAJ60
T cell receptor alpha joining 60 (pseudogene)
780
0.46
chr7_961818_962008 0.28 ADAP1
ArfGAP with dual PH domains 1
1387
0.35
chr11_121327677_121327828 0.28 RP11-730K11.1

4030
0.27
chr1_151028880_151029472 0.28 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
1058
0.29
chr3_32994118_32994336 0.28 CCR4
chemokine (C-C motif) receptor 4
1161
0.6
chr9_42587473_42587624 0.28 ENSG00000266353
.
7575
0.28
chr19_42381868_42382033 0.28 CD79A
CD79a molecule, immunoglobulin-associated alpha
575
0.62
chr11_82828119_82828301 0.28 PCF11
PCF11 cleavage and polyadenylation factor subunit
39820
0.12
chr4_108615033_108615184 0.28 PAPSS1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
26500
0.24
chr1_9690042_9690512 0.28 PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
21513
0.15
chr8_144437169_144437484 0.28 TOP1MT
topoisomerase (DNA) I, mitochondrial
890
0.4
chrX_47489439_47489603 0.28 CFP
complement factor properdin
157
0.92
chr3_121379230_121379471 0.28 HCLS1
hematopoietic cell-specific Lyn substrate 1
395
0.81
chr9_95857151_95857367 0.28 RP11-274J16.5

552
0.64
chr22_25574447_25574657 0.28 CRYBB3
crystallin, beta B3
21265
0.19
chr6_159074554_159074705 0.28 SYTL3
synaptotagmin-like 3
3583
0.22
chr9_70851276_70851465 0.28 CBWD3
COBW domain containing 3
5027
0.19
chr3_46248309_46248460 0.27 CCR1
chemokine (C-C motif) receptor 1
1503
0.46
chr7_127749136_127749293 0.27 ENSG00000207588
.
27301
0.2
chr17_66288424_66288865 0.27 ARSG
arylsulfatase G
985
0.41
chr1_28196256_28196434 0.27 THEMIS2
thymocyte selection associated family member 2
2710
0.16
chr8_38663717_38663929 0.27 TACC1
transforming, acidic coiled-coil containing protein 1
855
0.58
chr7_2445424_2445909 0.27 CHST12
carbohydrate (chondroitin 4) sulfotransferase 12
1932
0.35
chr10_11252091_11252492 0.27 RP3-323N1.2

38952
0.17
chr16_433636_433787 0.27 TMEM8A
transmembrane protein 8A
1729
0.2
chr6_35267664_35267815 0.27 DEF6
differentially expressed in FDCP 6 homolog (mouse)
2110
0.3
chr11_64627415_64627663 0.27 CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
15498
0.09
chr5_118644168_118644319 0.27 ENSG00000243333
.
1917
0.35
chr14_102281143_102281546 0.27 CTD-2017C7.2

4686
0.17
chr5_57788132_57788386 0.27 GAPT
GRB2-binding adaptor protein, transmembrane
995
0.57
chr3_18484841_18485200 0.27 SATB1
SATB homeobox 1
1345
0.38
chr2_127838932_127839401 0.26 BIN1
bridging integrator 1
25411
0.22
chr7_2568940_2569293 0.26 ENSG00000264357
.
2408
0.22
chr9_184434_184636 0.26 CBWD1
COBW domain containing 1
5463
0.2
chrX_111125721_111125872 0.26 TRPC5OS
TRPC5 opposite strand
671
0.81
chr10_23000499_23000660 0.26 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
2458
0.4
chr14_22972981_22973242 0.26 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
16940
0.09
chr1_32719471_32719691 0.26 LCK
lymphocyte-specific protein tyrosine kinase
2706
0.13
chr11_2466894_2467127 0.26 KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
789
0.56
chr9_117149358_117150269 0.26 AKNA
AT-hook transcription factor
430
0.85
chr13_48795269_48795575 0.26 ITM2B
integral membrane protein 2B
11872
0.26
chr15_34620156_34620427 0.26 SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
8754
0.11
chr3_141516104_141516959 0.26 ENSG00000265391
.
9778
0.19
chr20_44640151_44640302 0.26 MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
2679
0.18
chr11_48065579_48065730 0.26 AC103828.1

28247
0.17
chr1_1830918_1831069 0.26 RP1-140A9.1

8083
0.13
chrX_129307936_129308087 0.26 RAB33A
RAB33A, member RAS oncogene family
2388
0.3
chrX_128913537_128913688 0.26 SASH3
SAM and SH3 domain containing 3
348
0.88
chrX_78402769_78403059 0.26 GPR174
G protein-coupled receptor 174
23555
0.28
chr19_7742927_7743078 0.26 CTD-3214H19.16

385
0.62
chr15_93426430_93426631 0.26 CHD2
chromodomain helicase DNA binding protein 2
4
0.98
chr8_27262752_27262933 0.25 PTK2B
protein tyrosine kinase 2 beta
7873
0.23
chr16_85981545_85981835 0.25 IRF8
interferon regulatory factor 8
33771
0.2
chr7_150329208_150329551 0.25 GIMAP6
GTPase, IMAP family member 6
55
0.98
chr16_30077190_30078018 0.25 ALDOA
aldolase A, fructose-bisphosphate
96
0.92
chr6_128221625_128221781 0.25 THEMIS
thymocyte selection associated
400
0.91
chr2_237455550_237455701 0.25 ACKR3
atypical chemokine receptor 3
20805
0.22
chr7_38385599_38385750 0.25 AMPH
amphiphysin
117039
0.06
chr11_47415900_47416112 0.25 RP11-750H9.5

1185
0.28
chr11_64108374_64108555 0.25 CCDC88B
coiled-coil domain containing 88B
769
0.4
chr12_6899553_6899934 0.25 CD4
CD4 molecule
1009
0.28
chr21_46902731_46902882 0.25 COL18A1
collagen, type XVIII, alpha 1
7383
0.21
chr3_14418723_14418874 0.25 ENSG00000199609
.
17350
0.21
chr1_226066769_226066920 0.25 TMEM63A
transmembrane protein 63A
1465
0.3
chr9_34380533_34380766 0.24 C9orf24
chromosome 9 open reading frame 24
880
0.46
chr10_99080773_99080924 0.24 FRAT1
frequently rearranged in advanced T-cell lymphomas
1826
0.23
chr14_52331779_52331930 0.24 GNG2
guanine nucleotide binding protein (G protein), gamma 2
3812
0.25
chr6_20206247_20206398 0.24 RP11-239H6.2

5996
0.24
chr6_24920420_24920571 0.24 FAM65B
family with sequence similarity 65, member B
9300
0.23
chr3_88226589_88226740 0.24 C3orf38
chromosome 3 open reading frame 38
27527
0.17
chr6_90088751_90088902 0.24 UBE2J1
ubiquitin-conjugating enzyme E2, J1
26259
0.16
chr19_6481304_6482171 0.24 DENND1C
DENN/MADD domain containing 1C
27
0.95
chr6_2840474_2840660 0.24 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
1527
0.38
chr13_99910052_99910203 0.24 GPR18
G protein-coupled receptor 18
501
0.81
chr3_196339174_196339325 0.24 LINC01063
long intergenic non-protein coding RNA 1063
20209
0.12
chr3_114010788_114010939 0.24 TIGIT
T cell immunoreceptor with Ig and ITIM domains
914
0.57
chr21_46902934_46903368 0.24 COL18A1
collagen, type XVIII, alpha 1
7038
0.21
chr12_94543232_94543438 0.24 PLXNC1
plexin C1
836
0.67
chr11_10480387_10480598 0.24 AMPD3
adenosine monophosphate deaminase 3
2195
0.31
chr2_32490543_32490694 0.24 NLRC4
NLR family, CARD domain containing 4
183
0.95
chr1_154926399_154926550 0.24 PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
2106
0.14
chr19_17860667_17860818 0.24 FCHO1
FCH domain only 1
1544
0.29
chr1_154985461_154985619 0.24 ZBTB7B
zinc finger and BTB domain containing 7B
1384
0.19
chr22_24525287_24525438 0.24 CABIN1
calcineurin binding protein 1
26444
0.14
chr16_17107310_17107606 0.24 CTD-2576D5.4

120903
0.07
chrX_131351481_131352000 0.24 RAP2C
RAP2C, member of RAS oncogene family
412
0.59
chr2_30559834_30559985 0.24 ENSG00000221377
.
95405
0.07
chr16_84628728_84628899 0.24 RP11-61F12.1

814
0.61

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR5A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.4 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.4 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.1 0.3 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1 0.3 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.4 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 0.4 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.7 GO:0046645 regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1 0.2 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.3 GO:0006154 adenosine catabolic process(GO:0006154)
0.1 0.3 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.2 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.1 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.1 1.0 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.1 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.2 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.5 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.1 0.2 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1 0.2 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.1 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.5 GO:0045576 mast cell activation(GO:0045576)
0.1 0.3 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.2 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.1 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.3 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.1 0.2 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.1 GO:2001235 positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.2 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.3 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.3 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.3 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.4 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.2 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:1901021 activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0 0.3 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.3 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.6 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0002418 immune response to tumor cell(GO:0002418)
0.0 0.2 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.0 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0010870 positive regulation of receptor biosynthetic process(GO:0010870)
0.0 0.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0042772 DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.1 GO:0002327 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0046719 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.2 GO:0042094 interleukin-2 biosynthetic process(GO:0042094)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.2 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.0 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.2 GO:0016045 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.1 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.3 GO:0016577 histone demethylation(GO:0016577)
0.0 0.0 GO:0032418 lysosome localization(GO:0032418)
0.0 0.0 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.2 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.4 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 1.3 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.0 0.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.3 GO:0019674 NAD metabolic process(GO:0019674)
0.0 0.1 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.0 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.5 GO:0043928 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.5 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.6 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0003079 maternal aggressive behavior(GO:0002125) obsolete positive regulation of natriuresis(GO:0003079)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.2 GO:0098926 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:0009595 detection of biotic stimulus(GO:0009595)
0.0 0.1 GO:0051532 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.1 GO:0034030 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.2 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.2 GO:0002639 positive regulation of immunoglobulin production(GO:0002639)
0.0 0.1 GO:1903313 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.0 0.1 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.0 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0046688 response to copper ion(GO:0046688)
0.0 0.3 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0010821 regulation of mitochondrion organization(GO:0010821)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.1 GO:0033363 secretory granule organization(GO:0033363)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.0 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.0 GO:0015853 adenine transport(GO:0015853)
0.0 0.6 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.8 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.0 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.3 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.0 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.0 GO:0031497 chromatin assembly(GO:0031497)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0001504 neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.0 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.4 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.0 GO:0016265 obsolete death(GO:0016265)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 0.0 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.0 0.0 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0006067 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.0 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.9 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.1 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.5 GO:0006914 autophagy(GO:0006914)
0.0 0.0 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.0 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.2 GO:0043487 regulation of RNA stability(GO:0043487)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:1901070 guanosine-containing compound biosynthetic process(GO:1901070)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:0015669 gas transport(GO:0015669)
0.0 0.0 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.1 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.0 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.2 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1 1.4 GO:0001772 immunological synapse(GO:0001772)
0.1 0.5 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.2 GO:0000124 SAGA complex(GO:0000124)
0.1 0.2 GO:0042629 mast cell granule(GO:0042629)
0.1 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.0 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.8 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.5 GO:0005770 late endosome(GO:0005770)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.0 GO:0031045 dense core granule(GO:0031045)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.0 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.0 GO:0038201 TOR complex(GO:0038201)
0.0 0.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0070469 respiratory chain(GO:0070469)
0.0 1.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0001939 female pronucleus(GO:0001939)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.4 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.4 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.6 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.2 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.2 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.8 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.0 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0005416 sodium:amino acid symporter activity(GO:0005283) cation:amino acid symporter activity(GO:0005416)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.0 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.2 GO:0034739 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.0 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 1.0 GO:0017016 Ras GTPase binding(GO:0017016)
0.0 0.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.0 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 2.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 1.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID FOXO PATHWAY FoxO family signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.0 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.0 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.0 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.0 0.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)