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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for NRF1

Z-value: 4.04

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Transcription factors associated with NRF1

Gene Symbol	Gene ID	Gene Info
NRF1 Ensembl NCBI GeneCards UniProt	ENSG00000106459.10	nuclear respiratory factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_129214438_129214733	NRF1	36970	0.159753	-0.72	2.8e-02	Click!
chr7_129283603_129283833	NRF1	13473	0.226435	-0.70	3.7e-02	Click!
chr7_129252182_129253092	NRF1	1040	0.611378	0.66	5.1e-02	Click!
chr7_129257166_129257379	NRF1	5675	0.259725	0.64	6.2e-02	Click!
chr7_129304576_129304727	NRF1	7460	0.235823	-0.62	7.3e-02	Click!

Activity of the NRF1 motif across conditions

Conditions sorted by the z-value of the NRF1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_3522701_3522852	3.17	AC142528.1		270	0.77
chr22_24199875_24200057	2.86	SLC2A11	solute carrier family 2 (facilitated glucose transporter), member 11	184	0.81
chr20_35580060_35580211	2.74	SAMHD1	SAM domain and HD domain 1	24	0.98
chr16_2390815_2390992	2.56	ABCA3	ATP-binding cassette, sub-family A (ABC1), member 3	156	0.92
chr22_42095231_42095503	2.53	MEI1	meiosis inhibitor 1	136	0.92
chr6_31125997_31126148	2.33	CCHCR1	coiled-coil alpha-helical rod protein 1	57	0.73
chr19_49588476_49588627	2.32	SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	129	0.88
chr19_47363571_47364036	2.16	AP2S1	adaptor-related protein complex 2, sigma 1 subunit	9554	0.17
chr19_1383420_1383571	2.06	NDUFS7	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)	31	0.94
chr21_45209121_45209272	1.99	RRP1	ribosomal RNA processing 1	198	0.93
chr2_61372190_61372383	1.99	C2orf74	chromosome 2 open reading frame 74	43	0.98
chr13_95253751_95253983	1.96	GPR180	G protein-coupled receptor 180	290	0.91
chr20_34042583_34042833	1.95	GDF5	growth differentiation factor 5	140	0.64
chr19_56915357_56915660	1.94	ZNF583	zinc finger protein 583	125	0.92
chr19_48867207_48867576	1.88	TMEM143	transmembrane protein 143	75	0.73
chr5_169010500_169010651	1.86	SPDL1	spindle apparatus coiled-coil protein 1	63	0.98
chr19_36618863_36619073	1.85	CAPNS1	calpain, small subunit 1	11509	0.09
chr12_122230893_122231238	1.82	RHOF	ras homolog family member F (in filopodia)	201	0.93
chr18_10525775_10525964	1.76	NAPG	N-ethylmaleimide-sensitive factor attachment protein, gamma	157	0.97
chr17_36452726_36452901	1.72	MRPL45	mitochondrial ribosomal protein L45	176	0.94
chr19_50861631_50862161	1.72	NAPSA	napsin A aspartic peptidase	6986	0.09
chr19_49217598_49217896	1.71	MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator	2353	0.14
chrX_54835286_54835437	1.70	MAGED2	melanoma antigen family D, 2	132	0.96
chr15_73075798_73075989	1.69	ADPGK	ADP-dependent glucokinase	71	0.93
chr1_29101467_29102340	1.64	OPRD1	opioid receptor, delta 1	36751	0.12
chr11_65101112_65101263	1.64	DPF2	D4, zinc and double PHD fingers family 2	38	0.96
chr16_86588845_86588996	1.60	MTHFSD	methenyltetrahydrofolate synthetase domain containing	79	0.97
chr17_9479599_9480043	1.60	STX8	syntaxin 8	87	0.54
chr12_54070156_54070478	1.56	ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)	135	0.95
chr6_41040285_41040436	1.53	OARD1	O-acyl-ADP-ribose deacylase 1	7	0.82
chr19_11266572_11266789	1.51	SPC24	SPC24, NDC80 kinetochore complex component	196	0.92
chrX_17754862_17755280	1.51	SCML1	sex comb on midleg-like 1 (Drosophila)	517	0.86
chr15_63340381_63340577	1.51	TPM1	tropomyosin 1 (alpha)	86	0.94
chr16_30381739_30381890	1.49	TBC1D10B	TBC1 domain family, member 10B	229	0.65
chr11_64546452_64546665	1.49	SF1	splicing factor 1	300	0.83
chr20_3996304_3996483	1.49	RNF24	ring finger protein 24	164	0.96
chr9_140118033_140118193	1.49	C9orf169	chromosome 9 open reading frame 169	974	0.23
chr22_37172543_37172980	1.49	IFT27	intraflagellar transport 27 homolog (Chlamydomonas)	564	0.72
chr1_243418604_243419136	1.48	CEP170	centrosomal protein 170kDa	220	0.72
chr13_28712229_28712485	1.47	PAN3-AS1	PAN3 antisense RNA 1	27	0.8
chr2_113012718_113012869	1.45	ZC3H8	zinc finger CCCH-type containing 8	105	0.97
chr17_76254452_76254830	1.44	TMEM235	transmembrane protein 235	26519	0.12
chr5_52095855_52096006	1.43	CTD-2288O8.1		12070	0.19
chr16_57334462_57334613	1.42	PLLP	plasmolipin	15938	0.14
chr2_136634130_136634399	1.42	MCM6	minichromosome maintenance complex component 6	268	0.91
chr17_60005390_60005541	1.42	INTS2	integrator complex subunit 2	88	0.97
chr15_34330832_34331086	1.41	AVEN	apoptosis, caspase activation inhibitor	418	0.84
chr1_16939998_16940149	1.40	NBPF1	neuroblastoma breakpoint family, member 1	91	0.96
chr1_184723746_184723985	1.39	EDEM3	ER degradation enhancer, mannosidase alpha-like 3	164	0.96
chr20_61274054_61274358	1.39	SLCO4A1	solute carrier organic anion transporter family, member 4A1	409	0.47
chr10_104263741_104263944	1.38	SUFU	suppressor of fused homolog (Drosophila)	6	0.95
chr1_228075645_228075796	1.38	ENSG00000264483	.	53664	0.11
chr6_121655397_121655673	1.37	TBC1D32	TBC1 domain family, member 32	41	0.98
chr22_19419389_19419821	1.32	MRPL40	mitochondrial ribosomal protein L40	180	0.67
chr17_36003454_36003605	1.31	DDX52	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52	36	0.53
chr11_64739573_64739789	1.31	C11orf85	chromosome 11 open reading frame 85	124	0.92
chr12_54674066_54674261	1.30	HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	186	0.58
chr19_19496596_19496747	1.30	GATAD2A	GATA zinc finger domain containing 2A	29	0.97
chr5_150460010_150460252	1.29	TNIP1	TNFAIP3 interacting protein 1	446	0.84
chr3_4910344_4910625	1.29	ENSG00000239126	.	9902	0.2
chr14_78108377_78108627	1.28	SPTLC2	serine palmitoyltransferase, long chain base subunit 2	25386	0.16
chr17_4736385_4736546	1.27	MINK1	misshapen-like kinase 1	218	0.86
chr19_2427673_2427902	1.26	TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)	105	0.95
chr11_118271970_118272245	1.25	ATP5L	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G	238	0.69
chr16_279128_279418	1.25	LUC7L	LUC7-like (S. cerevisiae)	148	0.91
chr11_60609237_60609428	1.25	CCDC86	coiled-coil domain containing 86	212	0.83
chr19_16222015_16222208	1.24	RAB8A	RAB8A, member RAS oncogene family	328	0.84
chr19_46234272_46234446	1.24	FBXO46	F-box protein 46	197	0.85
chr5_217753_218381	1.24	CCDC127	coiled-coil domain containing 127	263	0.5
chr15_44116988_44117284	1.23	MFAP1	microfibrillar-associated protein 1	136	0.91
chr17_43298346_43298590	1.23	CTD-2020K17.1		664	0.36
chr7_99869720_99870133	1.22	GATS	GATS, stromal antigen 3 opposite strand	71	0.95
chr19_50432810_50433196	1.22	NUP62	nucleoporin 62kDa	2	0.66
chr8_117887202_117887456	1.22	RAD21	RAD21 homolog (S. pombe)	224	0.52
chrX_47517975_47518127	1.21	UXT-AS1	UXT antisense RNA 1	181	0.76
chr17_45570068_45570247	1.21	MRPL45P2	mitochondrial ribosomal protein L45 pseudogene 2	332	0.88
chr19_5827971_5828196	1.20	NRTN	neurturin	4270	0.1
chr2_232526625_232527001	1.20	ENSG00000239202	.	15829	0.16
chr2_20550724_20551509	1.20	PUM2	pumilio RNA-binding family member 2	653	0.67
chr15_78832765_78833017	1.19	PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	71	0.95
chr1_150336049_150336200	1.19	RPRD2	regulation of nuclear pre-mRNA domain containing 2	1002	0.47
chr21_30256992_30257908	1.19	N6AMT1	N-6 adenine-specific DNA methyltransferase 1 (putative)	243	0.95
chr9_100459687_100459908	1.18	XPA	xeroderma pigmentosum, complementation group A	158	0.94
chr5_70196258_70196507	1.18	SERF1A	small EDRK-rich factor 1A (telomeric)	110	0.97
chr2_3522990_3523243	1.18	AC142528.1		70	0.84
chr10_43951098_43951286	1.18	ENSG00000252532	.	2321	0.26
chr7_5821069_5821360	1.17	RNF216	ring finger protein 216	37	0.98
chr19_56116555_56116820	1.17	ZNF865	zinc finger protein 865	84	0.91
chr2_197791498_197791649	1.17	PGAP1	post-GPI attachment to proteins 1	104	0.98
chr22_18257315_18257654	1.16	BID	BH3 interacting domain death agonist	53	0.97
chr7_158936828_158937151	1.16	VIPR2	vasoactive intestinal peptide receptor 2	555	0.87
chr21_43640506_43640792	1.14	ENSG00000223262	.	634	0.47
chr1_213189220_213189371	1.14	ANGEL2	angel homolog 2 (Drosophila)	127	0.97
chr7_100861322_100861626	1.13	PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	199	0.75
chrX_24711721_24711887	1.13	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit	232	0.92
chr14_69094821_69095326	1.13	CTD-2325P2.4		89	0.98
chr1_29507945_29508271	1.13	SRSF4	serine/arginine-rich splicing factor 4	302	0.88
chr3_31573575_31573846	1.13	STT3B	STT3B, subunit of the oligosaccharyltransferase complex (catalytic)	572	0.85
chr22_50353929_50354264	1.12	PIM3	pim-3 oncogene	65	0.97
chr17_7137454_7137768	1.11	DVL2	dishevelled segment polarity protein 2	16	0.92
chr2_220042618_220042887	1.11	CNPPD1	cyclin Pas1/PHO80 domain containing 1	76	0.53
chr11_60681392_60681594	1.11	RP11-881M11.1		31	0.63
chr9_139685367_139685521	1.11	TMEM141	transmembrane protein 141	363	0.42
chr14_39643931_39644138	1.10	PNN	pinin, desmosome associated protein	353	0.85
chr21_40751925_40752262	1.10	WRB	tryptophan rich basic protein	77	0.96
chr16_30759639_30759938	1.10	PHKG2	phosphorylase kinase, gamma 2 (testis)	27	0.95
chr12_48499913_48500348	1.10	SENP1	SUMO1/sentrin specific peptidase 1	39	0.49
chr1_154976041_154976288	1.09	ZBTB7B	zinc finger and BTB domain containing 7B	869	0.33
chr17_17942741_17942956	1.08	GID4	GID complex subunit 4	89	0.78
chr3_47555010_47555200	1.08	ELP6	elongator acetyltransferase complex subunit 6	146	0.94
chr1_108508002_108508614	1.08	VAV3	vav 3 guanine nucleotide exchange factor	542	0.7
chr19_10676489_10676661	1.08	KRI1	KRI1 homolog (S. cerevisiae)	91	0.93
chr11_18656105_18656627	1.07	SPTY2D1	SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)	326	0.87
chr6_26123823_26124055	1.06	HIST1H2BC	histone cluster 1, H2bc	199	0.68
chr17_44344409_44344766	1.06	RP11-259G18.1		191	0.93
chr19_50887623_50887879	1.06	POLD1	polymerase (DNA directed), delta 1, catalytic subunit	121	0.91
chr5_81574185_81574688	1.06	RPS23	ribosomal protein S23	40	0.95
chr14_50319523_50319960	1.05	NEMF	nuclear export mediator factor	180	0.85
chr17_7518574_7518865	1.05	FXR2	fragile X mental retardation, autosomal homolog 2	530	0.41
chr1_149821944_149822390	1.05	HIST2H2AA4	histone cluster 2, H2aa4	476	0.5
chr13_95201650_95201933	1.04	TGDS	TDP-glucose 4,6-dehydratase	46720	0.13
chr7_75796010_75796256	1.04	AC005077.5		6918	0.18
chr6_153304524_153304798	1.04	FBXO5	F-box protein 5	53	0.73
chr16_2265076_2265283	1.04	PGP	phosphoglycolate phosphatase	371	0.61
chr4_178231041_178231773	1.04	NEIL3	nei endonuclease VIII-like 3 (E. coli)	417	0.87
chr4_184642511_184642662	1.04	ENSG00000251739	.	15502	0.17
chr19_17416354_17416505	1.04	MRPL34	mitochondrial ribosomal protein L34	48	0.92
chr5_64331070_64331877	1.04	ENSG00000207439	.	87723	0.1
chr20_18447768_18448009	1.04	DZANK1	double zinc ribbon and ankyrin repeat domains 1	59	0.57
chr18_158238_158410	1.04	USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	59	0.98
chr19_18058936_18059258	1.03	KCNN1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	3005	0.18
chr21_47648763_47648914	1.03	LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	100	0.73
chr18_20513344_20513796	1.03	RP11-739L10.1		157	0.44
chr17_27467519_27468040	1.03	RP11-321A17.4		278	0.55
chrX_47880068_47880219	1.03	SPACA5	sperm acrosome associated 5	12949	0.14
chr3_52188946_52189141	1.03	POC1A	POC1 centriolar protein A	337	0.85
chrX_133940887_133941194	1.02	FAM122C	family with sequence similarity 122C	183	0.94
chr16_31085838_31086052	1.02	ZNF646	zinc finger protein 646	181	0.6
chr5_162887153_162887344	1.02	HMMR	hyaluronan-mediated motility receptor (RHAMM)	39	0.57
chr12_112546663_112546943	1.01	NAA25	N(alpha)-acetyltransferase 25, NatB auxiliary subunit	23	0.97
chr1_40349190_40349341	1.00	TRIT1	tRNA isopentenyltransferase 1	87	0.95
chr5_10250450_10250920	1.00	CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	34	0.92
chr8_11626901_11627115	0.99	NEIL2	nei endonuclease VIII-like 2 (E. coli)	140	0.94
chr17_71188538_71188928	0.99	COG1	component of oligomeric golgi complex 1	396	0.83
chrX_7066413_7066788	0.99	HDHD1	haloacid dehalogenase-like hydrolase domain containing 1	369	0.71
chr5_138678038_138678710	0.99	PAIP2	poly(A) binding protein interacting protein 2	234	0.87
chr4_2043674_2043888	0.98	C4orf48	chromosome 4 open reading frame 48	4	0.66
chr12_69753428_69753934	0.98	YEATS4	YEATS domain containing 4	122	0.96
chr5_128430184_128430335	0.98	ISOC1	isochorismatase domain containing 1	185	0.96
chr3_143690649_143690852	0.98	C3orf58	chromosome 3 open reading frame 58	110	0.98
chr9_131843419_131843919	0.98	DOLPP1	dolichyldiphosphatase 1	256	0.86
chr1_33430206_33430511	0.98	RNF19B	ring finger protein 19B	72	0.96
chr13_34184631_34184800	0.98	RFC3	replication factor C (activator 1) 3, 38kDa	207471	0.02
chr16_8715324_8715502	0.97	METTL22	methyltransferase like 22	127	0.97
chr17_38279440_38280347	0.97	MSL1	male-specific lethal 1 homolog (Drosophila)	937	0.43
chr7_149275_149447	0.97	FAM20C	family with sequence similarity 20, member C	43608	0.16
chr6_33679104_33679457	0.97	UQCC2	ubiquinol-cytochrome c reductase complex assembly factor 2	181	0.93
chr1_234614585_234614936	0.97	TARBP1	TAR (HIV-1) RNA binding protein 1	89	0.98
chr21_38630680_38631091	0.97	DSCR3	Down syndrome critical region gene 3	8738	0.17
chr6_157542417_157542568	0.97	ARID1B	AT rich interactive domain 1B (SWI1-like)	72447	0.12
chr2_157189525_157189762	0.97	NR4A2	nuclear receptor subfamily 4, group A, member 2	411	0.9
chr22_31318038_31318328	0.96	MORC2-AS1	MORC2 antisense RNA 1	112	0.96
chr5_8457675_8458050	0.96	ENSG00000247516	.	3176	0.41
chr16_10837539_10837690	0.96	NUBP1	nucleotide binding protein 1	29	0.98
chr1_59012277_59012442	0.96	OMA1	OMA1 zinc metallopeptidase	19	0.98
chr17_33307453_33307681	0.95	LIG3	ligase III, DNA, ATP-dependent	2	0.9
chr10_45374254_45374405	0.95	TMEM72	transmembrane protein 72	32319	0.15
chr7_138915956_138916227	0.95	UBN2	ubinuclein 2	140	0.97
chr4_57844753_57845118	0.95	NOA1	nitric oxide associated 1	54	0.54
chr12_74931255_74931613	0.94	ATXN7L3B	ataxin 7-like 3B	117	0.94
chr1_206785946_206786193	0.94	EIF2D	eukaryotic translation initiation factor 2D	165	0.94
chr9_129567018_129567215	0.94	ZBTB43	zinc finger and BTB domain containing 43	169	0.96
chr1_149814537_149814930	0.93	HIST2H2AA3	histone cluster 2, H2aa3	255	0.75
chr10_104262463_104262753	0.93	ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	126	0.91
chr10_70231482_70231737	0.93	DNA2	DNA replication helicase/nuclease 2	34	0.97
chr2_128568808_128569035	0.93	WDR33	WD repeat domain 33	160	0.94
chr6_135502328_135502497	0.92	MYB	v-myb avian myeloblastosis viral oncogene homolog	41	0.98
chr12_107349405_107349556	0.92	C12orf23	chromosome 12 open reading frame 23	17	0.73
chr12_95397551_95397813	0.92	NDUFA12	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12	136	0.97
chr13_49105975_49106823	0.92	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	814	0.75
chr7_6487670_6487879	0.92	DAGLB	diacylglycerol lipase, beta	131	0.96
chr18_12883567_12883875	0.92	PTPN2	protein tyrosine phosphatase, non-receptor type 2	492	0.84
chr1_246670647_246670813	0.91	SMYD3	SET and MYND domain containing 3	116	0.97
chr12_133613669_133614058	0.91	ZNF84	zinc finger protein 84	15	0.97
chr6_143999142_144000093	0.91	PHACTR2	phosphatase and actin regulator 2	412	0.9
chr3_135915266_135915783	0.91	MSL2	male-specific lethal 2 homolog (Drosophila)	93	0.98
chr19_10305607_10305758	0.90	DNMT1	DNA (cytosine-5-)-methyltransferase 1	73	0.95
chr3_44379324_44379833	0.90	TCAIM	T cell activation inhibitor, mitochondrial	33	0.89
chr21_37692001_37692354	0.90	MORC3	MORC family CW-type zinc finger 3	310	0.75
chr6_27806407_27806618	0.90	HIST1H2BN	histone cluster 1, H2bn	72	0.8
chr5_75699014_75699893	0.89	IQGAP2	IQ motif containing GTPase activating protein 2	304	0.94
chr22_24236955_24237160	0.89	MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	866	0.41
chr19_11616618_11616769	0.89	ZNF653	zinc finger protein 653	45	0.95
chr2_64554540_64554897	0.89	ENSG00000264297	.	13175	0.25
chr22_42062744_42062895	0.88	ENSG00000207457	.	12896	0.1
chr14_21852624_21852819	0.88	RP11-524O1.4		270	0.49
chr1_8939232_8939383	0.88	ENO1	enolase 1, (alpha)	1	0.86
chr1_73101671_73101822	0.88	ENSG00000212366	.	81706	0.12
chr19_40791502_40791751	0.87	AKT2	v-akt murine thymoma viral oncogene homolog 2	183	0.89
chr6_27114265_27114575	0.87	HIST1H2BK	histone cluster 1, H2bk	157	0.74

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NRF1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	3.0	GO:0006273	lagging strand elongation(GO:0006273)
0.5	2.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.4	2.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.4	1.2	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.4	1.2	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.4	1.1	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.3	0.6	GO:0019372	lipoxygenase pathway(GO:0019372)
0.3	1.2	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.3	0.5	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.3	0.8	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.3	0.8	GO:0010815	bradykinin catabolic process(GO:0010815)
0.3	1.3	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.3	0.8	GO:0000212	meiotic spindle organization(GO:0000212)
0.2	0.2	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.2	0.7	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.2	1.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.2	0.7	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.2	0.7	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.2	0.9	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2	2.3	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2	0.7	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.2	1.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.2	2.2	GO:0007141	male meiosis I(GO:0007141)
0.2	0.9	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.2	0.9	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.2	0.6	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.2	0.6	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.2	1.0	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.2	1.5	GO:0033085	negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.2	1.0	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2	0.8	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.2	1.6	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.2	0.8	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.2	1.4	GO:0015851	nucleobase transport(GO:0015851)
0.2	1.4	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.2	0.8	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.2	1.0	GO:0045060	negative thymic T cell selection(GO:0045060)
0.2	0.6	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.2	1.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.2	3.2	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2	0.5	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.2	0.5	GO:0005997	xylulose metabolic process(GO:0005997)
0.2	0.5	GO:0006549	isoleucine metabolic process(GO:0006549)
0.2	1.0	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.2	0.5	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2	1.0	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.2	0.5	GO:0008215	spermine metabolic process(GO:0008215)
0.2	0.6	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.2	0.9	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.1	1.2	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.1	0.6	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	1.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.1	1.0	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.1	0.7	GO:0008356	asymmetric cell division(GO:0008356)
0.1	1.4	GO:0045843	negative regulation of striated muscle tissue development(GO:0045843)
0.1	0.3	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.1	0.6	GO:0051409	response to nitrosative stress(GO:0051409)
0.1	0.6	GO:0016266	O-glycan processing(GO:0016266)
0.1	2.0	GO:0006906	vesicle fusion(GO:0006906)
0.1	0.4	GO:0070669	response to interleukin-2(GO:0070669)
0.1	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.1	0.8	GO:0071168	protein localization to chromatin(GO:0071168)
0.1	0.5	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.1	0.9	GO:0006105	succinate metabolic process(GO:0006105)
0.1	0.7	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.1	0.5	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	2.6	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.1	0.4	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.1	0.6	GO:0009249	protein lipoylation(GO:0009249)
0.1	1.3	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1	1.5	GO:0016180	snRNA processing(GO:0016180)
0.1	0.5	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.3	GO:1900121	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1	1.0	GO:0015791	polyol transport(GO:0015791)
0.1	1.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	1.9	GO:0090630	activation of GTPase activity(GO:0090630)
0.1	0.5	GO:0060539	diaphragm development(GO:0060539)
0.1	0.2	GO:0071504	cellular response to heparin(GO:0071504)
0.1	0.2	GO:0006573	valine metabolic process(GO:0006573)
0.1	0.6	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.1	0.6	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.1	0.1	GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003339)
0.1	0.4	GO:0010508	positive regulation of autophagy(GO:0010508)
0.1	0.5	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	0.2	GO:0007028	cytoplasm organization(GO:0007028)
0.1	1.3	GO:0050812	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1	0.4	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1	0.6	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.1	0.4	GO:0006000	fructose metabolic process(GO:0006000)
0.1	0.2	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1	0.3	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.1	1.1	GO:0006301	postreplication repair(GO:0006301)
0.1	0.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1	0.7	GO:0043631	RNA polyadenylation(GO:0043631)
0.1	1.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.1	0.6	GO:0019042	viral latency(GO:0019042)
0.1	0.3	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.1	1.2	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.1	0.3	GO:0048859	formation of anatomical boundary(GO:0048859)
0.1	0.5	GO:0042559	pteridine-containing compound biosynthetic process(GO:0042559)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	1.0	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.1	1.2	GO:0050691	regulation of defense response to virus by host(GO:0050691)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.2	GO:0055089	fatty acid homeostasis(GO:0055089)
0.1	1.0	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.1	0.3	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.3	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	0.6	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.1	0.5	GO:0042891	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.1	0.3	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.1	1.5	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1	0.3	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.3	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1	0.4	GO:0001553	luteinization(GO:0001553)
0.1	0.7	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.1	0.3	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1	0.2	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	3.3	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.1	0.5	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1	0.2	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.1	0.2	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	0.4	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.2	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1	0.3	GO:0003032	detection of oxygen(GO:0003032)
0.1	0.5	GO:0031498	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1	0.2	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1	0.1	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.1	0.9	GO:0001782	B cell homeostasis(GO:0001782)
0.1	0.2	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.1	6.9	GO:0006334	nucleosome assembly(GO:0006334)
0.1	0.9	GO:0006825	copper ion transport(GO:0006825)
0.1	0.3	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.5	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.1	0.4	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.1	0.4	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.1	0.4	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.1	0.1	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.4	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.1	GO:0032261	purine nucleotide salvage(GO:0032261)
0.1	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.2	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.1	0.5	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.1	0.6	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.1	0.2	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	1.0	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.1	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.4	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1	0.2	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.1	0.2	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.3	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1	1.3	GO:0005980	glycogen catabolic process(GO:0005980)
0.1	0.6	GO:0048636	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.1	0.3	GO:0009067	aspartate family amino acid biosynthetic process(GO:0009067)
0.1	0.1	GO:0002634	regulation of germinal center formation(GO:0002634)
0.1	0.2	GO:0031297	replication fork processing(GO:0031297)
0.1	0.2	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.1	0.3	GO:0042921	corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.1	0.8	GO:0050684	regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.1	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	1.0	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.1	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.1	0.1	GO:1903170	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1	1.2	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1	0.5	GO:0072665	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.1	5.3	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1	1.6	GO:0006284	base-excision repair(GO:0006284)
0.1	0.3	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.1	0.2	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.1	0.2	GO:0015840	urea transport(GO:0015840)
0.1	0.2	GO:0002098	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.1	0.2	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.1	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.1	0.3	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.9	GO:0006312	mitotic recombination(GO:0006312)
0.1	0.3	GO:0033081	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1	0.2	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1	0.2	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.1	0.5	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.1	0.1	GO:0002902	regulation of B cell apoptotic process(GO:0002902)
0.1	0.3	GO:0032042	mitochondrial DNA metabolic process(GO:0032042)
0.1	1.4	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.1	0.6	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	0.2	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1	0.6	GO:0007020	microtubule nucleation(GO:0007020)
0.1	0.2	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.1	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.1	0.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.5	GO:0006555	methionine metabolic process(GO:0006555)
0.1	0.1	GO:0097576	vacuole fusion(GO:0097576)
0.1	0.7	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.1	2.3	GO:0006096	glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.1	0.5	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.1	2.7	GO:0051607	defense response to virus(GO:0051607)
0.1	2.0	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.1	0.2	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1	0.4	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1	0.4	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.1	0.8	GO:0032006	regulation of TOR signaling(GO:0032006)
0.1	0.2	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	0.3	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.1	0.2	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	3.3	GO:0022904	respiratory electron transport chain(GO:0022904)
0.0	0.2	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.0	0.1	GO:0034442	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0032727	interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727)
0.0	0.1	GO:0072239	metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0	0.2	GO:1902808	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.8	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0016137	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0	0.2	GO:0016265	obsolete death(GO:0016265)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.3	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	2.1	GO:0006479	protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0	0.6	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0	0.1	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.0	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	1.0	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.5	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	5.2	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.4	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.2	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.1	GO:0031929	TOR signaling(GO:0031929)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.3	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.2	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.7	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.4	GO:0051881	regulation of mitochondrial membrane potential(GO:0051881)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	1.1	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.0	GO:0034250	positive regulation of cellular amide metabolic process(GO:0034250)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.7	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.0	0.2	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.8	GO:1990266	neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0	0.5	GO:0016578	histone deubiquitination(GO:0016578)
0.0	2.7	GO:0008643	carbohydrate transport(GO:0008643)
0.0	0.3	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.6	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.5	GO:1903321	negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.0	0.2	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.8	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.0	0.4	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.3	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	2.1	GO:0000236	mitotic prometaphase(GO:0000236)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0048569	post-embryonic organ development(GO:0048569)
0.0	1.7	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.8	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.0	0.0	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	1.4	GO:0006986	response to unfolded protein(GO:0006986)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0051310	mitotic metaphase plate congression(GO:0007080) metaphase plate congression(GO:0051310)
0.0	0.2	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	1.5	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.4	GO:0042752	regulation of circadian rhythm(GO:0042752)
0.0	0.0	GO:0031055	chromatin remodeling at centromere(GO:0031055)
0.0	0.8	GO:0051028	mRNA transport(GO:0051028)
0.0	0.8	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
0.0	0.2	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	0.0	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	1.9	GO:0000209	protein polyubiquitination(GO:0000209)
0.0	0.9	GO:0061136	regulation of proteasomal protein catabolic process(GO:0061136)
0.0	0.2	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.5	GO:0006094	gluconeogenesis(GO:0006094)
0.0	1.2	GO:0006413	translational initiation(GO:0006413)
0.0	3.1	GO:0006184	obsolete GTP catabolic process(GO:0006184)
0.0	0.1	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.2	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.5	GO:0006071	glycerol metabolic process(GO:0006071) alditol metabolic process(GO:0019400)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.1	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	1.7	GO:0006364	rRNA processing(GO:0006364)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0046629	gamma-delta T cell differentiation(GO:0042492) gamma-delta T cell activation(GO:0046629)
0.0	0.1	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.4	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.2	GO:0001776	leukocyte homeostasis(GO:0001776)
0.0	0.3	GO:0036503	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.3	GO:0005977	glycogen metabolic process(GO:0005977)
0.0	0.6	GO:0070646	protein modification by small protein removal(GO:0070646)
0.0	0.1	GO:0032733	regulation of interleukin-10 production(GO:0032653) positive regulation of interleukin-10 production(GO:0032733)
0.0	0.2	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.2	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.3	GO:0006289	nucleotide-excision repair(GO:0006289)
0.0	0.2	GO:0006101	citrate metabolic process(GO:0006101) tricarboxylic acid metabolic process(GO:0072350)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.2	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.7	GO:0006338	chromatin remodeling(GO:0006338)
0.0	0.3	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	5.5	GO:0006412	translation(GO:0006412)
0.0	0.0	GO:0051322	anaphase(GO:0051322)
0.0	0.1	GO:0016446	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.2	GO:0030317	sperm motility(GO:0030317)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.9	GO:0016126	sterol biosynthetic process(GO:0016126)
0.0	0.0	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.3	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.3	GO:0006662	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.5	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.2	GO:0009070	serine family amino acid biosynthetic process(GO:0009070)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.1	GO:0036230	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0	0.3	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.0	GO:0051299	centrosome separation(GO:0051299)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.2	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.1	GO:0060251	regulation of glial cell proliferation(GO:0060251)
0.0	0.2	GO:2001020	regulation of response to DNA damage stimulus(GO:2001020)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.2	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.2	GO:1904030	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.2	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
0.0	0.0	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.4	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.3	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.1	GO:0030002	cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0042772	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.2	GO:0051320	mitotic S phase(GO:0000084) S phase(GO:0051320)
0.0	0.1	GO:0006402	mRNA catabolic process(GO:0006402)
0.0	0.3	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.4	GO:0006302	double-strand break repair(GO:0006302)
0.0	0.0	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.1	GO:0019079	viral genome replication(GO:0019079)
0.0	0.0	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139) positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.3	GO:0007602	phototransduction(GO:0007602)
0.0	0.5	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.4	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.5	GO:0031647	regulation of protein stability(GO:0031647)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	2.7	GO:0006396	RNA processing(GO:0006396)
0.0	0.1	GO:0001916	regulation of T cell mediated cytotoxicity(GO:0001914) positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0	0.2	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.0	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.0	GO:0021873	forebrain neuroblast division(GO:0021873)
0.0	0.1	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.0	GO:0007506	gonadal mesoderm development(GO:0007506)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.0	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.0	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.3	GO:0046209	nitric oxide metabolic process(GO:0046209) reactive nitrogen species metabolic process(GO:2001057)
0.0	0.1	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.3	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.1	GO:0007030	Golgi organization(GO:0007030)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.0	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
0.0	0.0	GO:0030432	peristalsis(GO:0030432)
0.0	0.0	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:1901216	positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0	0.3	GO:0006672	ceramide metabolic process(GO:0006672)
0.0	0.0	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.0	0.1	GO:0002456	T cell mediated immunity(GO:0002456)
0.0	0.1	GO:0010212	response to ionizing radiation(GO:0010212)
0.0	0.0	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.0	GO:0072141	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0	0.0	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.0	GO:0034763	negative regulation of transmembrane transport(GO:0034763)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.1	GO:0072487	MSL complex(GO:0072487)
0.6	1.8	GO:0032593	insulin-responsive compartment(GO:0032593)
0.5	2.7	GO:0042599	lamellar body(GO:0042599)
0.5	1.9	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.4	1.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.4	1.4	GO:0031262	Ndc80 complex(GO:0031262)
0.3	0.9	GO:0016939	kinesin II complex(GO:0016939)
0.3	1.2	GO:0032059	bleb(GO:0032059)
0.3	0.9	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.3	1.7	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.3	1.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.2	0.5	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.2	0.9	GO:0005826	actomyosin contractile ring(GO:0005826)
0.2	1.3	GO:0042575	DNA polymerase complex(GO:0042575)
0.2	2.6	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.2	1.3	GO:0042382	paraspeckles(GO:0042382)
0.2	0.8	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2	1.5	GO:0070688	MLL5-L complex(GO:0070688)
0.2	0.6	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2	1.2	GO:0030992	intraciliary transport particle B(GO:0030992)
0.2	0.6	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.2	0.6	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.2	0.5	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2	1.1	GO:0001527	microfibril(GO:0001527)
0.2	1.4	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.2	0.5	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2	1.4	GO:0042555	MCM complex(GO:0042555)
0.2	1.0	GO:0005869	dynactin complex(GO:0005869)
0.2	0.5	GO:0030008	TRAPP complex(GO:0030008)
0.2	0.8	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.2	0.9	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	1.8	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1	1.1	GO:0016342	catenin complex(GO:0016342)
0.1	1.5	GO:0032039	integrator complex(GO:0032039)
0.1	0.5	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	0.7	GO:0000805	X chromosome(GO:0000805)
0.1	0.5	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	2.0	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.1	0.5	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	0.5	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.7	GO:0005883	neurofilament(GO:0005883)
0.1	1.3	GO:0008278	cohesin complex(GO:0008278)
0.1	1.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	1.7	GO:0046930	pore complex(GO:0046930)
0.1	0.7	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1	1.5	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.1	0.7	GO:0016461	unconventional myosin complex(GO:0016461)
0.1	0.6	GO:0005682	U5 snRNP(GO:0005682)
0.1	4.0	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	0.4	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.6	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.1	3.8	GO:0005814	centriole(GO:0005814)
0.1	0.5	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	5.6	GO:0000786	nucleosome(GO:0000786)
0.1	0.6	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.5	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1	0.9	GO:0017119	Golgi transport complex(GO:0017119)
0.1	0.8	GO:0043202	lysosomal lumen(GO:0043202)
0.1	0.2	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.9	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	1.0	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	0.3	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.1	0.6	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	0.7	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	0.5	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.1	3.7	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1	0.5	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1	1.1	GO:0005801	cis-Golgi network(GO:0005801)
0.1	0.4	GO:0030894	replisome(GO:0030894) nuclear replisome(GO:0043601)
0.1	0.3	GO:0045120	pronucleus(GO:0045120)
0.1	0.9	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.3	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	0.9	GO:0043189	H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.4	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1	0.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.2	GO:0005686	U2 snRNP(GO:0005686)
0.1	6.8	GO:0005681	spliceosomal complex(GO:0005681)
0.1	0.2	GO:0070695	FHF complex(GO:0070695)
0.1	0.3	GO:0042788	polysomal ribosome(GO:0042788)
0.1	1.0	GO:0031519	PcG protein complex(GO:0031519)
0.1	0.4	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1	0.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.1	0.7	GO:0016235	aggresome(GO:0016235)
0.1	0.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	0.4	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	0.7	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.1	0.2	GO:0005775	vacuolar lumen(GO:0005775)
0.1	0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	0.3	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.2	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	3.7	GO:0016607	nuclear speck(GO:0016607)
0.0	0.2	GO:0030904	retromer complex(GO:0030904)
0.0	0.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.2	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	2.0	GO:0055037	recycling endosome(GO:0055037)
0.0	3.9	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	2.4	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	1.6	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.3	GO:0071203	WASH complex(GO:0071203)
0.0	0.5	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	2.6	GO:0031227	intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	1.6	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	1.7	GO:0000502	proteasome complex(GO:0000502)
0.0	0.8	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	1.1	GO:0015935	small ribosomal subunit(GO:0015935)
0.0	0.5	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686) PeBoW complex(GO:0070545)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.7	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.4	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.3	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	2.2	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	1.8	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.4	GO:0031201	SNARE complex(GO:0031201)
0.0	1.2	GO:0031301	integral component of organelle membrane(GO:0031301)
0.0	0.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	1.2	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.4	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0070461	SAGA-type complex(GO:0070461)
0.0	0.2	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.4	GO:0005922	connexon complex(GO:0005922)
0.0	2.5	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.0	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.8	GO:0030496	midbody(GO:0030496)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.8	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.3	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.2	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.5	GO:0031514	motile cilium(GO:0031514)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.6	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	1.3	GO:0000785	chromatin(GO:0000785)
0.0	0.5	GO:0043204	perikaryon(GO:0043204)
0.0	0.3	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.5	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.1	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	3.4	GO:0031966	mitochondrial membrane(GO:0031966)
0.0	0.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.7	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.9	GO:0016604	nuclear body(GO:0016604)
0.0	8.7	GO:0005739	mitochondrion(GO:0005739)
0.0	1.4	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.0	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.3	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	5.4	GO:0005654	nucleoplasm(GO:0005654)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0030684	preribosome(GO:0030684)
0.0	0.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.0	GO:0097525	spliceosomal snRNP complex(GO:0097525)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.6	GO:0016882	cyclo-ligase activity(GO:0016882)
0.4	1.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.3	1.0	GO:0003896	DNA primase activity(GO:0003896)
0.3	1.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.3	0.9	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.3	0.9	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.3	0.8	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.3	2.2	GO:0001671	ATPase activator activity(GO:0001671)
0.3	1.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.3	0.5	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.3	1.0	GO:0070061	fructose binding(GO:0070061)
0.3	0.8	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2	0.7	GO:0035184	histone threonine kinase activity(GO:0035184)
0.2	1.4	GO:0050733	RS domain binding(GO:0050733)
0.2	2.6	GO:0048038	quinone binding(GO:0048038)
0.2	0.7	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2	0.9	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.2	0.6	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	0.6	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.2	0.6	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2	1.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2	0.6	GO:0050544	arachidonic acid binding(GO:0050544)
0.2	1.0	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.2	2.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2	0.6	GO:0004739	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2	1.5	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2	0.6	GO:0070644	vitamin D response element binding(GO:0070644)
0.2	2.0	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2	0.5	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.2	1.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.2	0.9	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2	0.2	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.2	0.8	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.2	0.5	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.2	0.7	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.2	0.8	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2	0.8	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2	0.9	GO:0015288	porin activity(GO:0015288)
0.2	1.5	GO:0005123	death receptor binding(GO:0005123)
0.1	0.1	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	0.7	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.1	0.6	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.8	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.7	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.1	0.7	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1	1.3	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	0.5	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.5	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	0.6	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.4	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	0.5	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1	0.5	GO:0016531	copper chaperone activity(GO:0016531)
0.1	1.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	1.0	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.7	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	0.6	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.5	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	0.5	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	0.5	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	2.9	GO:0051119	sugar transmembrane transporter activity(GO:0051119)
0.1	0.1	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	0.6	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.1	0.6	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.1	0.6	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.1	GO:0048256	flap endonuclease activity(GO:0048256)
0.1	0.7	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	0.5	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.3	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1	0.3	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.1	0.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.6	GO:0031996	thioesterase binding(GO:0031996)
0.1	0.4	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.7	GO:0030371	translation repressor activity(GO:0030371)
0.1	1.2	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.1	1.9	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	0.4	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	1.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	0.3	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	1.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.4	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	0.6	GO:0051920	peroxiredoxin activity(GO:0051920)
0.1	0.3	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.6	GO:0070628	proteasome binding(GO:0070628)
0.1	0.6	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1	0.7	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.1	0.2	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.1	0.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.3	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1	0.2	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.5	GO:0030507	spectrin binding(GO:0030507)
0.1	0.1	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1	0.5	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1	3.1	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	0.3	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	0.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.3	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	1.4	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.1	0.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.3	GO:0005536	glucose binding(GO:0005536)
0.1	0.7	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.1	0.5	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.4	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	0.6	GO:0016866	intramolecular transferase activity(GO:0016866)
0.1	0.2	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1	1.2	GO:0035064	methylated histone binding(GO:0035064)
0.1	0.2	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1	0.9	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	0.2	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.3	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.1	0.2	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	1.8	GO:0008137	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1	0.2	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.1	0.6	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.1	1.4	GO:0003724	RNA helicase activity(GO:0003724)
0.1	2.9	GO:0008276	protein methyltransferase activity(GO:0008276)
0.1	0.4	GO:0005522	profilin binding(GO:0005522)
0.1	1.8	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.1	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	1.3	GO:0000049	tRNA binding(GO:0000049)
0.1	0.5	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	0.3	GO:0004075	biotin carboxylase activity(GO:0004075)
0.1	4.2	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.9	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.5	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	0.2	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	1.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	2.4	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	4.3	GO:0016566	obsolete specific transcriptional repressor activity(GO:0016566)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.8	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.5	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.6	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	1.1	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.6	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.9	GO:0015485	cholesterol binding(GO:0015485)
0.0	1.0	GO:0003684	damaged DNA binding(GO:0003684)
0.0	0.6	GO:0019894	kinesin binding(GO:0019894)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.9	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.2	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.3	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.6	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.5	GO:0016830	carbon-carbon lyase activity(GO:0016830)
0.0	0.3	GO:0090079	translation regulator activity, nucleic acid binding(GO:0090079)
0.0	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.8	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.2	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	2.3	GO:0031072	heat shock protein binding(GO:0031072)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	1.0	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	2.3	GO:0031625	ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0	2.1	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0004532	exoribonuclease activity(GO:0004532)
0.0	0.4	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.2	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.0	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.5	GO:0004527	exonuclease activity(GO:0004527)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	1.9	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	2.2	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.9	GO:0001104	transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.5	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	6.2	GO:0016874	ligase activity(GO:0016874)
0.0	0.5	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	1.0	GO:0004180	carboxypeptidase activity(GO:0004180)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	2.3	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.9	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	1.0	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.0	1.0	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0045182	translation regulator activity(GO:0045182)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.3	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.7	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.9	GO:0019783	ubiquitin-like protein-specific protease activity(GO:0019783)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.3	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.2	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	12.1	GO:0003723	RNA binding(GO:0003723)
0.0	0.5	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.3	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.9	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.5	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.5	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.8	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.8	GO:0004386	helicase activity(GO:0004386)
0.0	0.1	GO:0004112	cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0	0.7	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.5	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
0.0	0.9	GO:0008017	microtubule binding(GO:0008017)
0.0	5.2	GO:0005525	GTP binding(GO:0005525)
0.0	0.2	GO:0051117	ATPase binding(GO:0051117)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.4	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.0	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.4	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.3	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.6	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.2	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.9	GO:0004518	nuclease activity(GO:0004518)
0.0	0.2	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.1	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.2	GO:0008483	transaminase activity(GO:0008483)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.3	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
0.0	0.1	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.7	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	17.6	GO:0008270	zinc ion binding(GO:0008270)
0.0	0.2	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0042393	histone binding(GO:0042393)
0.0	0.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.0	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.0	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.0	GO:0001515	opioid peptide activity(GO:0001515)
0.0	2.0	GO:0005125	cytokine activity(GO:0005125)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.0	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.0	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.2	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.8	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	1.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	1.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.4	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	1.7	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	1.6	PID ALK1 PATHWAY	ALK1 signaling events
0.1	0.4	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	0.7	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	4.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	1.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	4.2	PID E2F PATHWAY	E2F transcription factor network
0.1	1.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	0.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	2.0	PID PLK1 PATHWAY	PLK1 signaling events
0.1	0.7	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	1.9	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	1.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	1.1	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	1.3	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.7	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	1.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	1.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	1.0	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.2	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	1.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	1.1	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.3	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.8	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	0.6	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.0	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	1.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.4	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.8	PID P73PATHWAY	p73 transcription factor network
0.0	0.4	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	1.0	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.7	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.4	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.3	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.1	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.5	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.0	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.3	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.2	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.1	PID ATM PATHWAY	ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.7	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.2	2.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	2.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	1.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	2.8	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	7.0	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	1.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	1.6	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	1.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	6.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	0.6	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.1	1.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	1.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	0.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	1.0	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	1.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	0.6	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	0.8	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	2.8	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.1	2.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	0.6	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	5.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	0.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.7	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.1	0.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	1.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	0.9	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	0.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	1.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	0.9	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	0.6	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1	1.2	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	1.0	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	1.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	0.9	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	0.9	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	0.7	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	1.6	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	1.1	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	2.4	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	0.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.9	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	1.5	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME BASE EXCISION REPAIR	Genes involved in Base Excision Repair
0.0	0.9	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	2.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.7	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.5	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.5	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.9	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	2.4	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	0.3	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.4	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.8	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.5	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.5	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	1.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.5	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.0	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.7	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	1.0	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	3.0	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	1.8	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	1.0	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.7	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.8	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones

Results for NRF1

Z-value: 4.04

Motif logo

Transcription factors associated with NRF1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the NRF1 motif across conditions

Conditions sorted by the z-value of the NRF1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NRF1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: