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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for OLIG1

Z-value: 0.60

Motif logo

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Transcription factors associated with OLIG1

Gene Symbol Gene ID Gene Info
OLIG1
ENSG00000184221.8 oligodendrocyte transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr21_34437191_34437342OLIG151840.189671-0.442.4e-01Click!
chr21_34439565_34439843OLIG127460.235935-0.422.7e-01Click!
chr21_34431903_34432054OLIG1104720.170916-0.373.3e-01Click!
chr21_34431477_34431628OLIG1108980.1701000.333.8e-01Click!
chr21_34428465_34428616OLIG1139100.164800-0.333.9e-01Click!

Activity of the OLIG1 motif across conditions

Conditions sorted by the z-value of the OLIG1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chrX_128913998_128914362 0.39 SASH3
 SAM and SH3 domain containing 3
 220
 0.94
chr1_25254983_25255134 0.36 RUNX3
 runt-related transcription factor 3
 554
 0.81
chr19_42056193_42056486 0.35 CEACAM21
 carcinoembryonic antigen-related cell adhesion molecule 21
 453
 0.8
chr1_185283352_185283831 0.33 IVNS1ABP
 influenza virus NS1A binding protein
 2870
 0.28
chr12_62657019_62657170 0.31 USP15
 ubiquitin specific peptidase 15
 2885
 0.26
chr1_248729435_248729591 0.30 RP11-438F14.3
3612
 0.13
chr1_84610455_84610717 0.30 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
 632
 0.82
chr5_162930555_162931177 0.30 MAT2B
 methionine adenosyltransferase II, beta
 746
 0.62
chr2_127415089_127415240 0.30 GYPC
 glycophorin C (Gerbich blood group)
 1404
 0.55
chr12_57077777_57078354 0.29 PTGES3
 prostaglandin E synthase 3 (cytosolic)
 3881
 0.14
chr14_53593743_53594005 0.29 DDHD1
 DDHD domain containing 1
 22930
 0.17
chr13_43564402_43564714 0.29 EPSTI1
 epithelial stromal interaction 1 (breast)
 809
 0.73
chr8_66863582_66864279 0.29 DNAJC5B
 DnaJ (Hsp40) homolog, subfamily C, member 5 beta
 69865
 0.12
chr2_241630055_241630353 0.29 AQP12A
 aquaporin 12A
 1058
 0.43
chr13_46754554_46754849 0.28 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 1758
 0.31
chr1_248644857_248645289 0.28 RP11-407H12.8
3712
 0.13
chr10_28656896_28657047 0.28 MPP7
 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
 33556
 0.16
chr5_171612568_171612893 0.28 STK10
 serine/threonine kinase 10
 2660
 0.27
chr3_67735991_67736422 0.27 SUCLG2
 succinate-CoA ligase, GDP-forming, beta subunit
 31168
 0.25
chr1_25875695_25876149 0.27 LDLRAP1
 low density lipoprotein receptor adaptor protein 1
 5851
 0.23
chr11_118087619_118088223 0.27 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 2315
 0.23
chr7_2739070_2739221 0.27 AMZ1
 archaelysin family metallopeptidase 1
 11309
 0.21
chr17_263982_264133 0.27 AC108004.3
243
 0.89
chr18_9138515_9138757 0.26 ANKRD12
 ankyrin repeat domain 12
 1075
 0.42
chr13_52396131_52396530 0.26 RP11-327P2.5
17897
 0.18
chr22_24824729_24824978 0.26 ADORA2A
 adenosine A2a receptor
 1323
 0.44
chr4_89534455_89534711 0.26 HERC3
 HECT and RLD domain containing E3 ubiquitin protein ligase 3
 7638
 0.19
chr12_9806335_9806486 0.26 RP11-705C15.2
131
 0.93
chr2_182325663_182326116 0.26 ITGA4
 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
 3734
 0.36
chr8_66751756_66751954 0.26 PDE7A
 phosphodiesterase 7A
 872
 0.73
chr5_148189087_148189390 0.26 ADRB2
 adrenoceptor beta 2, surface
 16918
 0.25
chr16_29674660_29674967 0.25 QPRT
 quinolinate phosphoribosyltransferase
 213
 0.51
chr16_10971555_10971960 0.25 CIITA
 class II, major histocompatibility complex, transactivator
 690
 0.64
chr17_38719353_38719597 0.25 CCR7
 chemokine (C-C motif) receptor 7
 2210
 0.28
chr1_26872331_26872899 0.25 RPS6KA1
 ribosomal protein S6 kinase, 90kDa, polypeptide 1
 272
 0.88
chr11_14668160_14668311 0.25 PDE3B
 phosphodiesterase 3B, cGMP-inhibited
 2858
 0.29
chr20_24046827_24047099 0.25 GGTLC1
 gamma-glutamyltransferase light chain 1
 77547
 0.11
chr6_135408926_135409077 0.24 HBS1L
 HBS1-like (S. cerevisiae)
 15193
 0.21
chr17_35860978_35861129 0.24 DUSP14
 dual specificity phosphatase 14
 8928
 0.19
chr7_26895188_26895339 0.24 SKAP2
 src kinase associated phosphoprotein 2
 1976
 0.43
chr5_43310867_43311162 0.24 HMGCS1
 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
 2312
 0.32
chr14_61814847_61814998 0.23 PRKCH
 protein kinase C, eta
 313
 0.91
chr6_159465378_159465638 0.23 TAGAP
 T-cell activation RhoGTPase activating protein
 542
 0.78
chr12_53616534_53616822 0.23 RARG
 retinoic acid receptor, gamma
 2481
 0.17
chr14_90086040_90086276 0.23 FOXN3
 forkhead box N3
 665
 0.59
chr14_22978649_22978851 0.23 TRAJ15
 T cell receptor alpha joining 15
 19830
 0.09
chr13_50114703_50115207 0.23 RCBTB1
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
 26504
 0.17
chr17_10603321_10603720 0.23 ADPRM
 ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
 2609
 0.18
chr4_6677782_6677978 0.23 AC093323.1
 Uncharacterized protein
 16309
 0.14
chr3_16330847_16330998 0.23 OXNAD1
 oxidoreductase NAD-binding domain containing 1
 20174
 0.15
chr6_153321108_153321259 0.23 MTRF1L
 mitochondrial translational release factor 1-like
 2637
 0.24
chr2_158291882_158292250 0.23 CYTIP
 cytohesin 1 interacting protein
 3860
 0.26
chr17_74188552_74188703 0.23 RNF157
 ring finger protein 157
 25464
 0.11
chr1_169672728_169672969 0.22 SELL
 selectin L
 7991
 0.2
chr4_6753172_6753335 0.22 KIAA0232
 KIAA0232
 31116
 0.13
chr20_35575234_35575857 0.22 SAMHD1
 SAM domain and HD domain 1
 4566
 0.25
chr13_97879341_97880219 0.22 MBNL2
 muscleblind-like splicing regulator 2
 5171
 0.33
chrX_118811810_118811961 0.22 SEPT6
 septin 6
 14907
 0.16
chr5_134712559_134712710 0.22 H2AFY
 H2A histone family, member Y
 22267
 0.15
chr4_143325352_143326244 0.22 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 26614
 0.28
chr4_40199107_40199293 0.22 RHOH
 ras homolog family member H
 673
 0.73
chrX_53741093_53741244 0.22 HUWE1
 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
 27495
 0.23
chr14_98443744_98443895 0.21 C14orf64
 chromosome 14 open reading frame 64
 564
 0.87
chr1_23668742_23669298 0.21 HNRNPR
 heterogeneous nuclear ribonucleoprotein R
 1735
 0.29
chr10_121352939_121353112 0.21 TIAL1
 TIA1 cytotoxic granule-associated RNA binding protein-like 1
 2982
 0.3
chr7_150414088_150414577 0.21 GIMAP1
 GTPase, IMAP family member 1
 687
 0.65
chr10_13828862_13829013 0.21 RP11-353M9.1
57554
 0.1
chr1_229642144_229642295 0.21 NUP133
 nucleoporin 133kDa
 1854
 0.24
chr14_64974613_64974785 0.21 ZBTB25
 zinc finger and BTB domain containing 25
 2768
 0.16
chr9_80524074_80524374 0.21 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 86309
 0.1
chr14_102290786_102291012 0.21 CTD-2017C7.2
14241
 0.14
chr14_64204420_64204571 0.21 ENSG00000252749
 .
 1333
 0.43
chr12_46659525_46659676 0.21 SLC38A1
 solute carrier family 38, member 1
 1884
 0.48
chr5_44713608_44713759 0.21 ENSG00000263556
 .
 2609
 0.4
chr2_202050412_202050706 0.21 CASP10
 caspase 10, apoptosis-related cysteine peptidase
 2641
 0.22
chr22_40858602_40858925 0.20 MKL1
 megakaryoblastic leukemia (translocation) 1
 659
 0.7
chr14_91879481_91879632 0.20 CCDC88C
 coiled-coil domain containing 88C
 4134
 0.28
chr18_53002274_53002527 0.20 TCF4
 transcription factor 4
 12875
 0.28
chr13_48984563_48985023 0.20 LPAR6
 lysophosphatidic acid receptor 6
 16250
 0.26
chr11_67176258_67176520 0.20 TBC1D10C
 TBC1 domain family, member 10C
 4729
 0.07
chr5_156731259_156731410 0.20 CYFIP2
 cytoplasmic FMR1 interacting protein 2
 6711
 0.16
chr21_43516995_43517146 0.20 C21orf128
 chromosome 21 open reading frame 128
 11574
 0.19
chr1_150847141_150847524 0.20 ARNT
 aryl hydrocarbon receptor nuclear translocator
 1723
 0.26
chr7_5518487_5518712 0.20 ENSG00000238394
 .
 6427
 0.13
chr18_8610996_8611147 0.20 RAB12
 RAB12, member RAS oncogene family
 1628
 0.4
chr1_84611671_84611822 0.20 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
 1792
 0.48
chr5_58880144_58880439 0.20 PDE4D
 phosphodiesterase 4D, cAMP-specific
 1928
 0.5
chr8_29948388_29948539 0.19 LEPROTL1
 leptin receptor overlapping transcript-like 1
 4451
 0.17
chr1_89737127_89737489 0.19 GBP5
 guanylate binding protein 5
 762
 0.66
chr18_60824857_60825062 0.19 RP11-299P2.1
6406
 0.25
chr22_40858328_40858544 0.19 MKL1
 megakaryoblastic leukemia (translocation) 1
 986
 0.54
chr10_112624321_112624902 0.19 PDCD4
 programmed cell death 4 (neoplastic transformation inhibitor)
 6954
 0.15
chr6_26442034_26442281 0.19 BTN3A3
 butyrophilin, subfamily 3, member A3
 1371
 0.29
chr3_45706571_45706792 0.19 LIMD1-AS1
 LIMD1 antisense RNA 1
 23693
 0.16
chr1_167891180_167891331 0.19 ADCY10
 adenylate cyclase 10 (soluble)
 7802
 0.18
chr1_211502580_211502753 0.19 TRAF5
 TNF receptor-associated factor 5
 2487
 0.35
chr20_24090206_24090357 0.18 GGTLC1
 gamma-glutamyltransferase light chain 1
 120865
 0.06
chr9_98782803_98783372 0.18 ERCC6L2
 excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2
 47968
 0.15
chr1_150737104_150737638 0.18 CTSS
 cathepsin S
 897
 0.5
chr6_143249356_143249507 0.18 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 16907
 0.25
chr18_13277168_13277319 0.18 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
 859
 0.63
chr15_67374785_67374936 0.18 SMAD3
 SMAD family member 3
 16060
 0.25
chr11_58342434_58343027 0.18 LPXN
 leupaxin
 604
 0.68
chr5_114193091_114193242 0.18 RP11-492A10.1
189059
 0.03
chr3_63923691_63923842 0.18 ATXN7
 ataxin 7
 25491
 0.15
chr7_142353602_142353808 0.18 MTRNR2L6
 MT-RNR2-like 6
 20399
 0.23
chr14_99726709_99727240 0.18 AL109767.1
2311
 0.33
chr12_66712096_66712247 0.18 HELB
 helicase (DNA) B
 15846
 0.16
chr3_141218856_141219007 0.18 RASA2
 RAS p21 protein activator 2
 13040
 0.21
chr9_3528863_3529151 0.18 RFX3
 regulatory factor X, 3 (influences HLA class II expression)
 3003
 0.37
chr4_129026129_129026280 0.18 LARP1B
 La ribonucleoprotein domain family, member 1B
 27208
 0.24
chr9_117150863_117151014 0.18 AKNA
 AT-hook transcription factor
 577
 0.77
chr5_148726675_148726837 0.18 GRPEL2
 GrpE-like 2, mitochondrial (E. coli)
 1691
 0.25
chr3_176915816_176916502 0.18 TBL1XR1
 transducin (beta)-like 1 X-linked receptor 1
 898
 0.7
chr15_90119818_90119983 0.18 TICRR
 TOPBP1-interacting checkpoint and replication regulator
 1082
 0.46
chr6_99380366_99380517 0.18 FBXL4
 F-box and leucine-rich repeat protein 4
 15361
 0.28
chr1_169662937_169663139 0.18 SELL
 selectin L
 17801
 0.18
chr5_35857770_35858187 0.18 IL7R
 interleukin 7 receptor
 984
 0.58
chr15_77287169_77287320 0.18 PSTPIP1
 proline-serine-threonine phosphatase interacting protein 1
 182
 0.95
chr1_19717605_19717920 0.17 CAPZB
 capping protein (actin filament) muscle Z-line, beta
 5471
 0.18
chr1_32716475_32716711 0.17 LCK
 lymphocyte-specific protein tyrosine kinase
 247
 0.82
chr2_182329799_182329950 0.17 ITGA4
 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
 7719
 0.31
chr2_237446083_237446280 0.17 IQCA1
 IQ motif containing with AAA domain 1
 29996
 0.19
chr10_126431099_126431666 0.17 FAM53B
 family with sequence similarity 53, member B
 157
 0.95
chr10_63979683_63979834 0.17 RTKN2
 rhotekin 2
 16264
 0.26
chr2_70321937_70322218 0.17 PCBP1-AS1
 PCBP1 antisense RNA 1
 6099
 0.17
chr6_74232761_74232916 0.17 RP11-505P4.7
503
 0.51
chr7_148408377_148408528 0.17 CUL1
 cullin 1
 12448
 0.17
chr3_27922887_27923131 0.17 EOMES
 eomesodermin
 158803
 0.04
chr1_239883177_239883989 0.17 CHRM3
 cholinergic receptor, muscarinic 3
 740
 0.59
chr4_109081890_109082041 0.17 LEF1
 lymphoid enhancer-binding factor 1
 5492
 0.25
chr13_36407967_36408118 0.17 DCLK1
 doublecortin-like kinase 1
 21737
 0.28
chr1_89457123_89457381 0.17 CCBL2
 cysteine conjugate-beta lyase 2
 1035
 0.37
chr3_149419430_149419681 0.17 WWTR1
 WW domain containing transcription regulator 1
 1505
 0.39
chr18_56215999_56216150 0.17 RP11-126O1.2
8228
 0.17
chr2_55236798_55237891 0.17 RTN4
 reticulon 4
 241
 0.93
chr3_66514964_66515132 0.17 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
 36308
 0.22
chr19_42432968_42433149 0.17 ARHGEF1
 Rho guanine nucleotide exchange factor (GEF) 1
 5812
 0.14
chr12_68044712_68044863 0.17 DYRK2
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
 462
 0.87
chr3_59996849_59997073 0.17 NPCDR1
 nasopharyngeal carcinoma, down-regulated 1
 39378
 0.24
chr5_110560941_110561277 0.17 CAMK4
 calcium/calmodulin-dependent protein kinase IV
 1325
 0.51
chr19_1465997_1466148 0.17 ENSG00000267317
 .
 3308
 0.09
chr3_18475636_18475787 0.17 SATB1
 SATB homeobox 1
 1034
 0.57
chr1_230307234_230307385 0.17 RP5-956O18.2
96920
 0.07
chr6_75924948_75925099 0.17 COL12A1
 collagen, type XII, alpha 1
 9256
 0.22
chr6_143264256_143264520 0.17 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 1950
 0.43
chr2_106372259_106372410 0.17 NCK2
 NCK adaptor protein 2
 10146
 0.29
chr9_4664226_4664377 0.17 PPAPDC2
 phosphatidic acid phosphatase type 2 domain containing 2
 2003
 0.26
chr11_62367040_62367191 0.17 MTA2
 metastasis associated 1 family, member 2
 326
 0.7
chr2_38825620_38825771 0.17 HNRNPLL
 heterogeneous nuclear ribonucleoprotein L-like
 1473
 0.39
chr12_133083232_133083480 0.16 FBRSL1
 fibrosin-like 1
 16199
 0.2
chr5_75842727_75842878 0.16 IQGAP2
 IQ motif containing GTPase activating protein 2
 432
 0.88
chr1_198873027_198873178 0.16 ENSG00000207759
 .
 44820
 0.17
chr11_117685491_117685642 0.16 DSCAML1
 Down syndrome cell adhesion molecule like 1
 2674
 0.19
chr1_158903283_158903483 0.16 PYHIN1
 pyrin and HIN domain family, member 1
 2025
 0.36
chr12_10019991_10020525 0.16 RP11-290C10.1
632
 0.61
chr3_141745583_141745864 0.16 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
 1716
 0.46
chr7_7960072_7960471 0.16 ENSG00000201747
 .
 14121
 0.18
chr1_156722427_156722776 0.16 HDGF
 hepatoma-derived growth factor
 361
 0.75
chr3_151989454_151989605 0.16 MBNL1-AS1
 MBNL1 antisense RNA 1
 2185
 0.3
chr15_33493746_33494182 0.16 FMN1
 formin 1
 7067
 0.29
chr11_62358316_62359010 0.16 TUT1
 terminal uridylyl transferase 1, U6 snRNA-specific
 332
 0.71
chr5_95170159_95170387 0.16 GLRX
 glutaredoxin (thioltransferase)
 11564
 0.14
chr19_16195500_16195773 0.16 TPM4
 tropomyosin 4
 3103
 0.21
chr1_204490030_204490190 0.16 MDM4
 Mdm4 p53 binding protein homolog (mouse)
 4491
 0.2
chr21_16816003_16816154 0.16 ENSG00000212564
 .
 170524
 0.04
chr1_244487830_244488005 0.16 C1orf100
 chromosome 1 open reading frame 100
 28020
 0.22
chr9_102972411_102972625 0.16 ENSG00000239908
 .
 107677
 0.06
chr5_74965499_74965780 0.16 ENSG00000207333
 .
 39785
 0.14
chr11_11865444_11865596 0.16 USP47
 ubiquitin specific peptidase 47
 1907
 0.47
chr7_106505707_106506635 0.16 PIK3CG
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
 247
 0.95
chr4_56773645_56773796 0.16 ENSG00000202358
 .
 21959
 0.16
chr22_40914778_40915024 0.16 RP4-591N18.2
2903
 0.23
chrX_153023566_153023717 0.16 PLXNB3
 plexin B3
 6010
 0.1
chr21_37670145_37670473 0.16 MORC3
 MORC family CW-type zinc finger 3
 22178
 0.13
chr5_118623311_118623849 0.16 ENSG00000243333
 .
 18746
 0.17
chr3_71503791_71503942 0.16 ENSG00000221264
 .
 87374
 0.09
chr12_121829638_121829987 0.16 ANAPC5
 anaphase promoting complex subunit 5
 7887
 0.2
chr22_50631230_50631436 0.16 TRABD
 TraB domain containing
 110
 0.82
chr5_79251776_79251927 0.16 RP11-168A11.1
19449
 0.2
chr1_108328348_108328499 0.16 ENSG00000265536
 .
 9545
 0.26
chr2_197030897_197031094 0.16 STK17B
 serine/threonine kinase 17b
 4729
 0.22
chr11_11865222_11865373 0.16 USP47
 ubiquitin specific peptidase 47
 1684
 0.51
chr12_55372250_55372401 0.16 TESPA1
 thymocyte expressed, positive selection associated 1
 3297
 0.29
chr1_225968168_225968319 0.15 SRP9
 signal recognition particle 9kDa
 2606
 0.22
chr6_26304754_26304905 0.15 HIST1H4H
 histone cluster 1, H4h
 19067
 0.08
chr20_10481692_10481843 0.15 SLX4IP
 SLX4 interacting protein
 65816
 0.11
chr14_25134813_25134997 0.15 GZMB
 granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
 31432
 0.15
chr4_146098361_146098512 0.15 OTUD4
 OTU domain containing 4
 871
 0.65
chr4_153022445_153022684 0.15 ENSG00000266244
 .
 127056
 0.05
chr1_26644827_26645344 0.15 UBXN11
 UBX domain protein 11
 231
 0.76
chr14_91869059_91869463 0.15 CCDC88C
 coiled-coil domain containing 88C
 14429
 0.23
chr18_56355169_56355320 0.15 RP11-126O1.4
10398
 0.15
chr2_200490274_200490425 0.15 SATB2
 SATB homeobox 2
 154360
 0.04
chr5_130881277_130881428 0.15 RAPGEF6
 Rap guanine nucleotide exchange factor (GEF) 6
 12626
 0.29
chr4_178237433_178237648 0.15 NEIL3
 nei endonuclease VIII-like 3 (E. coli)
 6550
 0.23
chr4_146541198_146541349 0.15 MMAA
 methylmalonic aciduria (cobalamin deficiency) cblA type
 1858
 0.37
chr12_118795905_118796056 0.15 TAOK3
 TAO kinase 3
 930
 0.65
chr6_12065087_12065238 0.15 HIVEP1
 human immunodeficiency virus type I enhancer binding protein 1
 49342
 0.17
chr4_113444412_113444838 0.15 NEUROG2
 neurogenin 2
 7297
 0.19

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.2 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1 0.4 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.4 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.2 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0048143 astrocyte activation(GO:0048143)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0052257 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:0031063 regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.0 GO:0015825 L-serine transport(GO:0015825)
0.0 0.0 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.1 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.0 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0043489 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.0 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.0 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.0 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.0 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0035269 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.0 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.0 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0050860 regulation of T cell receptor signaling pathway(GO:0050856) negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.0 GO:0035751 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0042403 thyroid hormone metabolic process(GO:0042403)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.0 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.0 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.0 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.0 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.0 GO:0035004 phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.0 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.0 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0017069 snRNA binding(GO:0017069)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.0 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.0 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family