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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for OLIG2_NEUROD1_ATOH1

Z-value: 1.26

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Transcription factors associated with OLIG2_NEUROD1_ATOH1

Gene Symbol	Gene ID	Gene Info
OLIG2 Ensembl NCBI GeneCards UniProt	ENSG00000205927.4	oligodendrocyte transcription factor 2
NEUROD1 Ensembl NCBI GeneCards UniProt	ENSG00000162992.3	neuronal differentiation 1
ATOH1 Ensembl NCBI GeneCards UniProt	ENSG00000172238.3	atonal bHLH transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr4_94749488_94749739	ATOH1	429	0.879995	0.64	6.3e-02	Click!
chr4_94750731_94750882	ATOH1	764	0.732053	0.59	9.5e-02	Click!
chr4_94749767_94750023	ATOH1	147	0.970769	0.59	9.6e-02	Click!
chr4_94750171_94750322	ATOH1	204	0.958334	0.34	3.7e-01	Click!
chr4_94750547_94750698	ATOH1	580	0.814317	0.23	5.6e-01	Click!
chr2_182546068_182546219	NEUROD1	540	0.716081	-0.21	5.9e-01	Click!
chr2_182545553_182545957	NEUROD1	152	0.947177	-0.07	8.5e-01	Click!
chr21_34415498_34415672	OLIG2	17342	0.163952	0.93	2.4e-04	Click!
chr21_34415086_34415237	OLIG2	16918	0.165161	0.93	3.3e-04	Click!
chr21_34398837_34398988	OLIG2	669	0.716984	0.70	3.6e-02	Click!
chr21_34398214_34398768	OLIG2	248	0.929091	0.68	4.5e-02	Click!
chr21_34399098_34399249	OLIG2	930	0.592307	0.63	7.1e-02	Click!

Activity of the OLIG2_NEUROD1_ATOH1 motif across conditions

Conditions sorted by the z-value of the OLIG2_NEUROD1_ATOH1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_127822596_127822803	0.82	BIN1	bridging integrator 1	41878	0.16
chr2_164592268_164592669	0.77	FIGN	fidgetin	49	0.99
chr15_39871853_39872515	0.75	THBS1	thrombospondin 1	1096	0.52
chr1_230223080_230223231	0.60	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	20137	0.23
chr1_8932959_8933177	0.59	ENO1-IT1	ENO1 intronic transcript 1 (non-protein coding)	4998	0.14
chr19_41104181_41104507	0.58	LTBP4	latent transforming growth factor beta binding protein 4	1203	0.38
chr9_109459969_109460612	0.57	ENSG00000200131	.	18032	0.28
chr14_95235148_95235528	0.56	GSC	goosecoid homeobox	1224	0.6
chr2_239757510_239758069	0.55	TWIST2	twist family bHLH transcription factor 2	1116	0.62
chr10_6779919_6780270	0.55	PRKCQ	protein kinase C, theta	157831	0.04
chr6_48037466_48037693	0.53	PTCHD4	patched domain containing 4	1154	0.67
chr17_72426935_72427098	0.53	GPRC5C	G protein-coupled receptor, family C, group 5, member C	36	0.97
chr3_99349211_99349490	0.52	COL8A1	collagen, type VIII, alpha 1	7969	0.28
chr1_32042837_32043215	0.52	TINAGL1	tubulointerstitial nephritis antigen-like 1	887	0.47
chr20_52789675_52790234	0.51	CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1	234	0.95
chr1_17560057_17560274	0.51	PADI1	peptidyl arginine deiminase, type I	315	0.88
chr11_460592_460743	0.51	RP13-317D12.3		3232	0.12
chr17_55945610_55945963	0.51	CUEDC1	CUE domain containing 1	1010	0.52
chr17_7492744_7493045	0.50	SOX15	SRY (sex determining region Y)-box 15	496	0.46
chr11_13119960_13120111	0.49	ENSG00000266625	.	134848	0.05
chr18_8615592_8616115	0.49	RAB12	RAB12, member RAS oncogene family	6410	0.21
chr20_60892287_60892438	0.48	RP11-157P1.4		10981	0.12
chr4_115520348_115520872	0.48	UGT8	UDP glycosyltransferase 8	684	0.8
chr12_50482265_50482493	0.47	SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	361	0.78
chr7_150784606_150785150	0.47	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	724	0.46
chr20_6032553_6033205	0.46	LRRN4	leucine rich repeat neuronal 4	1816	0.35
chr3_127174283_127174496	0.45	TPRA1	transmembrane protein, adipocyte asscociated 1	124891	0.05
chr6_27584810_27585278	0.45	ENSG00000238648	.	14144	0.19
chr10_99648580_99648731	0.45	CRTAC1	cartilage acidic protein 1	4656	0.2
chr8_67434316_67434584	0.44	ENSG00000206949	.	20904	0.17
chr2_75426626_75426804	0.44	TACR1	tachykinin receptor 1	111	0.98
chr22_51135201_51135410	0.44	ENSG00000206841	.	5514	0.12
chr13_31439124_31439427	0.44	MEDAG	mesenteric estrogen-dependent adipogenesis	41053	0.16
chr1_32135114_32135265	0.43	COL16A1	collagen, type XVI, alpha 1	3507	0.16
chr6_169278047_169278198	0.43	SMOC2	SPARC related modular calcium binding 2	224358	0.02
chr2_231191950_231192650	0.42	SP140L	SP140 nuclear body protein-like	315	0.92
chr6_152701966_152702349	0.42	SYNE1-AS1	SYNE1 antisense RNA 1	476	0.79
chr14_106369996_106370147	0.42	ENSG00000211923	.	314	0.34
chr7_29324592_29324856	0.42	AC004593.3		76138	0.1
chr13_76259054_76259476	0.42	LMO7	LIM domain 7	48806	0.13
chr20_62328885_62329036	0.42	TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	939	0.35
chr1_207202821_207202972	0.41	C1orf116	chromosome 1 open reading frame 116	3196	0.17
chr6_90928649_90929126	0.41	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	77574	0.1
chr8_90323500_90323651	0.41	RIPK2	receptor-interacting serine-threonine kinase 2	446400	0.01
chr7_42275396_42275690	0.41	GLI3	GLI family zinc finger 3	1069	0.7
chr5_2750019_2750705	0.41	IRX2	iroquois homeobox 2	1407	0.43
chr16_121276_121527	0.40	RHBDF1	rhomboid 5 homolog 1 (Drosophila)	1228	0.28
chr1_230223344_230223516	0.40	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	20412	0.23
chr8_99836773_99837010	0.40	STK3	serine/threonine kinase 3	1008	0.66
chr17_62051929_62052085	0.40	SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	1729	0.26
chr3_98609388_98609782	0.40	DCBLD2	discoidin, CUB and LCCL domain containing 2	10430	0.18
chr10_13748985_13749251	0.40	ENSG00000222235	.	2140	0.21
chr1_49259010_49259161	0.40	BEND5	BEN domain containing 5	16495	0.28
chrX_19716745_19716896	0.40	SH3KBP1	SH3-domain kinase binding protein 1	27704	0.25
chr5_66334972_66335234	0.39	MAST4	microtubule associated serine/threonine kinase family member 4	34620	0.19
chr10_105599590_105599741	0.39	SH3PXD2A	SH3 and PX domains 2A	15499	0.19
chr19_46270378_46270670	0.39	AC074212.6		530	0.46
chr17_39779390_39779541	0.39	KRT17	keratin 17	55	0.95
chr1_116380584_116380832	0.39	NHLH2	nescient helix loop helix 2	2654	0.36
chr10_88728248_88728709	0.38	ADIRF	adipogenesis regulatory factor	289	0.5
chr7_45002030_45002849	0.38	RP4-647J21.1		1931	0.25
chr15_90380123_90380631	0.38	ENSG00000264966	.	13576	0.11
chr1_152082781_152083810	0.38	TCHH	trichohyalin	3261	0.18
chr21_18214928_18215293	0.38	ENSG00000239023	.	123793	0.06
chr2_131594749_131594981	0.38	ARHGEF4	Rho guanine nucleotide exchange factor (GEF) 4	163	0.67
chr5_172659939_172660230	0.38	NKX2-5	NK2 homeobox 5	2125	0.3
chr9_89952337_89952906	0.38	ENSG00000212421	.	77256	0.11
chr2_208105325_208105697	0.38	AC007879.5		13465	0.21
chr10_95143500_95143651	0.38	MYOF	myoferlin	98376	0.07
chr2_162275011_162275548	0.37	TBR1	T-box, brain, 1	873	0.56
chr6_111947186_111947610	0.37	TRAF3IP2	TRAF3 interacting protein 2	19917	0.16
chr1_24469240_24469593	0.37	IL22RA1	interleukin 22 receptor, alpha 1	195	0.94
chr2_129063011_129063600	0.37	HS6ST1	heparan sulfate 6-O-sulfotransferase 1	12846	0.24
chr19_17940819_17940970	0.37	INSL3	insulin-like 3 (Leydig cell)	8511	0.11
chr22_42710235_42710386	0.37	TCF20	transcription factor 20 (AR1)	29312	0.18
chr12_112196119_112196270	0.37	RP11-162P23.2		4500	0.2
chr4_85886471_85886934	0.36	WDFY3	WD repeat and FYVE domain containing 3	801	0.75
chr4_125065453_125065672	0.36	ANKRD50	ankyrin repeat domain 50	568325	0.0
chr17_74525686_74525960	0.36	CYGB	cytoglobin	2324	0.14
chr4_10107960_10108187	0.36	ENSG00000223086	.	9435	0.16
chr12_54393540_54393854	0.36	HOXC-AS1	HOXC cluster antisense RNA 1	97	0.62
chr6_34191164_34191315	0.36	HMGA1	high mobility group AT-hook 1	13411	0.2
chr20_9389767_9389966	0.36	PLCB4	phospholipase C, beta 4	101419	0.07
chr8_142083367_142083518	0.36	DENND3	DENN/MADD domain containing 3	43935	0.14
chr1_956379_957022	0.36	AGRN	agrin	1197	0.27
chr8_37372289_37372565	0.36	RP11-150O12.6		2112	0.43
chr4_124426780_124427488	0.35	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	106011	0.08
chr19_34972293_34972513	0.35	WTIP	Wilms tumor 1 interacting protein	140	0.95
chr19_39142719_39142948	0.35	ACTN4	actinin, alpha 4	4455	0.14
chrX_153029718_153029902	0.35	PLXNB3	plexin B3	84	0.93
chr4_88029433_88029643	0.35	AFF1	AF4/FMR2 family, member 1	58734	0.14
chr9_688099_688250	0.35	RP11-130C19.3		2619	0.32
chr19_11372274_11372425	0.34	DOCK6	dedicator of cytokinesis 6	779	0.49
chr11_57406082_57406969	0.34	AP000662.4		676	0.5
chr4_80572253_80572434	0.34	OR7E94P	olfactory receptor, family 7, subfamily E, member 94 pseudogene	63059	0.15
chr4_53507302_53507475	0.34	USP46	ubiquitin specific peptidase 46	15369	0.2
chr3_150089259_150089633	0.34	TSC22D2	TSC22 domain family, member 2	36676	0.21
chr15_86329767_86329918	0.34	KLHL25	kelch-like family member 25	8258	0.12
chr11_2738826_2738977	0.34	KCNQ1OT1	KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)	17677	0.22
chr1_170630467_170630618	0.34	PRRX1	paired related homeobox 1	1733	0.5
chr12_71833793_71834525	0.34	LGR5	leucine-rich repeat containing G protein-coupled receptor 5	344	0.86
chr5_10077992_10078143	0.34	CTD-2256P15.1		170370	0.03
chr10_73019820_73020069	0.34	UNC5B-AS1	UNC5B antisense RNA 1	41959	0.12
chr14_78447028_78447687	0.34	ENSG00000199440	.	159872	0.03
chr11_119303601_119304219	0.34	THY1	Thy-1 cell surface antigen	8215	0.14
chr12_6420537_6420688	0.33	PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	513	0.73
chr6_12573623_12573848	0.33	PHACTR1	phosphatase and actin regulator 1	144158	0.05
chr2_241374262_241374834	0.33	GPC1	glypican 1	540	0.75
chr19_42710829_42711018	0.33	DEDD2	death effector domain containing 2	10898	0.09
chr7_44298624_44298775	0.33	CAMK2B	calcium/calmodulin-dependent protein kinase II beta	16794	0.18
chr10_21625398_21625641	0.33	ENSG00000207264	.	14629	0.25
chr10_126389149_126389300	0.33	FAM53B-AS1	FAM53B antisense RNA 1	2970	0.28
chrX_19906774_19906925	0.32	SH3KBP1	SH3-domain kinase binding protein 1	1130	0.6
chr11_1897109_1897260	0.32	LSP1	lymphocyte-specific protein 1	523	0.63
chr10_43248840_43249724	0.32	BMS1	BMS1 ribosome biogenesis factor	28967	0.19
chr11_57087212_57087483	0.32	TNKS1BP1	tankyrase 1 binding protein 1, 182kDa	2324	0.17
chr5_106741120_106741311	0.32	EFNA5	ephrin-A5	265113	0.02
chr14_91735710_91735943	0.32	GPR68	G protein-coupled receptor 68	15557	0.16
chr15_59560035_59560196	0.32	RP11-429D19.1		3246	0.19
chr2_174983381_174983564	0.32	OLA1	Obg-like ATPase 1	99202	0.07
chr3_73673648_73674178	0.32	PDZRN3	PDZ domain containing ring finger 3	78	0.96
chr6_101841770_101842075	0.32	GRIK2	glutamate receptor, ionotropic, kainate 2	4742	0.37
chr22_50744615_50744936	0.32	PLXNB2	plexin B2	1242	0.27
chr9_140352440_140352691	0.32	NSMF	NMDA receptor synaptonuclear signaling and neuronal migration factor	576	0.63
chr5_135364769_135365006	0.31	TGFBI	transforming growth factor, beta-induced, 68kDa	196	0.95
chr22_30087528_30087679	0.31	RP1-76B20.12		28100	0.11
chr13_86372735_86372886	0.31	SLITRK6	SLIT and NTRK-like family, member 6	813	0.79
chr7_102632036_102632223	0.31	NFE4	nuclear factor, erythroid 4	18160	0.14
chr20_62085538_62085770	0.31	RP11-358D14.2		6250	0.13
chr21_30517898_30518405	0.31	ENSG00000201984	.	6446	0.14
chr8_32077875_32078317	0.31	NRG1-IT2	NRG1 intronic transcript 2 (non-protein coding)	348	0.9
chr17_27506561_27506872	0.31	MYO18A	myosin XVIIIA	666	0.68
chr6_158181766_158181950	0.31	SNX9	sorting nexin 9	62438	0.11
chr11_126870507_126870686	0.31	KIRREL3	kin of IRRE like 3 (Drosophila)	59	0.96
chr19_41729247_41729598	0.31	CTD-2195B23.3		1466	0.28
chr3_58012091_58012242	0.31	FLNB	filamin B, beta	18039	0.25
chr20_61297836_61297987	0.31	RP11-93B14.5		63	0.94
chr20_47299051_47299422	0.31	ENSG00000251876	.	56749	0.16
chr8_86937269_86937426	0.31	ATP6V0D2	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2	62205	0.14
chr3_51425020_51425499	0.31	MANF	mesencephalic astrocyte-derived neurotrophic factor	2781	0.26
chr11_61047532_61047683	0.30	VWCE	von Willebrand factor C and EGF domains	6329	0.14
chr17_6797470_6797621	0.30	ALOX12P2	arachidonate 12-lipoxygenase pseudogene 2	444	0.79
chr20_61463695_61464080	0.30	COL9A3	collagen, type IX, alpha 3	14724	0.11
chr20_43921897_43922225	0.30	MATN4	matrilin 4	12170	0.12
chr3_64801656_64801807	0.30	ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9	128055	0.05
chr17_17726041_17726867	0.30	SREBF1	sterol regulatory element binding transcription factor 1	478	0.73
chr8_22023419_22024083	0.30	BMP1	bone morphogenetic protein 1	951	0.4
chr20_18039503_18040184	0.30	RP4-726N1.2		294	0.83
chr17_38614815_38615028	0.30	IGFBP4	insulin-like growth factor binding protein 4	15208	0.13
chr9_71177567_71177718	0.30	TMEM252	transmembrane protein 252	21859	0.24
chr12_54402958_54403134	0.30	HOXC8	homeobox C8	214	0.8
chr1_235133406_235133693	0.30	ENSG00000239690	.	93616	0.08
chr17_74666825_74666976	0.30	RP11-318A15.2		1124	0.31
chr2_163174641_163175537	0.30	IFIH1	interferon induced with helicase C domain 1	105	0.76
chr12_109729676_109729841	0.30	FOXN4	forkhead box N4	5230	0.23
chr13_30168298_30169638	0.29	SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	857	0.74
chr19_49654515_49654666	0.29	HRC	histidine rich calcium binding protein	2102	0.15
chr12_54390992_54391173	0.29	HOXC-AS2	HOXC cluster antisense RNA 2	513	0.46
chr10_112113893_112114201	0.29	SMNDC1	survival motor neuron domain containing 1	49338	0.14
chr9_80499174_80499388	0.29	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	61366	0.15
chr19_32477992_32478143	0.29	ENSG00000221504	.	60588	0.15
chr2_115384761_115384912	0.29	DPP10	dipeptidyl-peptidase 10 (non-functional)	165656	0.04
chr4_75230404_75230837	0.29	EREG	epiregulin	240	0.93
chr17_1618285_1618721	0.29	ENSG00000186594	.	1218	0.24
chr13_110521954_110522217	0.29	ENSG00000201161	.	45358	0.18
chr1_224804905_224805156	0.29	CNIH3	cornichon family AMPA receptor auxiliary protein 3	1035	0.41
chr7_6437932_6438083	0.29	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	23837	0.15
chr3_28617795_28617996	0.29	LINC00693	long intergenic non-protein coding RNA 693	7	0.99
chr12_78334342_78334902	0.29	NAV3	neuron navigator 3	25434	0.27
chr3_42113480_42113939	0.29	TRAK1	trafficking protein, kinesin binding 1	18853	0.25
chr16_11295551_11295900	0.29	RMI2	RecQ mediated genome instability 2	47781	0.08
chr12_10874089_10875353	0.29	YBX3	Y box binding protein 3	1185	0.46
chr17_73718603_73718754	0.29	ITGB4	integrin, beta 4	1101	0.34
chr1_197880677_197880955	0.29	LHX9	LIM homeobox 9	805	0.69
chr1_116381723_116382451	0.29	NHLH2	nescient helix loop helix 2	1275	0.57
chr3_33319990_33320141	0.29	FBXL2	F-box and leucine-rich repeat protein 2	1097	0.59
chr10_74436092_74436294	0.29	MCU	mitochondrial calcium uniporter	15696	0.15
chr7_96653818_96654015	0.29	DLX5	distal-less homeobox 5	346	0.86
chr9_113800702_113801367	0.29	LPAR1	lysophosphatidic acid receptor 1	53	0.98
chr1_153587674_153587825	0.29	S100A14	S100 calcium binding protein A14	665	0.44
chr19_3346586_3346737	0.29	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	12900	0.17
chr17_694312_694463	0.29	RP11-676J12.8		622	0.63
chr14_37050333_37050591	0.29	NKX2-8	NK2 homeobox 8	1350	0.4
chr12_122235813_122236047	0.29	RHOF	ras homolog family member F (in filopodia)	2653	0.22
chr9_139240222_139240529	0.28	GPSM1	G-protein signaling modulator 1	7134	0.12
chr1_26127054_26127674	0.28	SEPN1	selenoprotein N, 1	680	0.54
chr2_160918347_160919586	0.28	PLA2R1	phospholipase A2 receptor 1, 180kDa	155	0.98
chr6_33636840_33636991	0.28	SBP1	SBP1; Uncharacterized protein	26559	0.11
chr18_9825005_9825225	0.28	ENSG00000242651	.	5509	0.21
chr17_34611752_34612896	0.28	CCL3L1	chemokine (C-C motif) ligand 3-like 1	13395	0.14
chr4_85873557_85873708	0.28	WDFY3	WD repeat and FYVE domain containing 3	13871	0.26
chr2_227623803_227624269	0.28	IRS1	insulin receptor substrate 1	40439	0.16
chr16_14597742_14597893	0.28	AC092291.2		32975	0.17
chr17_65361877_65362420	0.28	PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	573	0.7
chr19_4061458_4061934	0.28	CTD-2622I13.3		1051	0.37
chr16_62068318_62068835	0.28	CDH8	cadherin 8, type 2	462	0.9
chr2_106012197_106012348	0.28	FHL2	four and a half LIM domains 2	970	0.58
chr14_52116783_52117087	0.28	FRMD6	FERM domain containing 6	1641	0.39
chr5_160265170_160265321	0.28	ATP10B	ATPase, class V, type 10B	13974	0.28
chr1_205418778_205418941	0.28	LEMD1	LEM domain containing 1	200	0.91

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG2_NEUROD1_ATOH1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0003079	obsolete positive regulation of natriuresis(GO:0003079)
0.1	0.4	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.4	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.4	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.5	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.1	0.5	GO:0018101	protein citrullination(GO:0018101)
0.1	0.4	GO:0009414	response to water deprivation(GO:0009414)
0.1	0.3	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.3	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.1	0.3	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.4	GO:0072070	loop of Henle development(GO:0072070)
0.1	0.3	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.2	GO:0060539	diaphragm development(GO:0060539)
0.1	0.2	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.5	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.1	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.2	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.1	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.2	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.2	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.1	0.2	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.2	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.1	0.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.2	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.1	0.2	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1	0.3	GO:0006561	proline biosynthetic process(GO:0006561)
0.1	0.2	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.3	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	0.2	GO:0070141	response to UV-A(GO:0070141)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	0.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.0	GO:0031392	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.2	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0044266	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.7	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.2	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.2	GO:0090026	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.7	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.2	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.2	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.2	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.1	GO:0070977	organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0	0.2	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.5	GO:0035329	hippo signaling(GO:0035329)
0.0	0.3	GO:0045843	negative regulation of striated muscle tissue development(GO:0045843)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.0	GO:0070099	regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.1	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0072141	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0	0.1	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.2	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0010269	response to selenium ion(GO:0010269)
0.0	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.1	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.1	GO:0021873	forebrain neuroblast division(GO:0021873)
0.0	0.2	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.2	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.2	GO:0060438	trachea development(GO:0060438)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.4	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.0	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.2	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.2	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.1	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0016115	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.1	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.2	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.2	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.2	GO:0055093	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.0	GO:0032682	negative regulation of chemokine production(GO:0032682)
0.0	0.2	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.0	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.0	1.1	GO:0034332	adherens junction organization(GO:0034332)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.2	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.0	GO:0060068	vagina development(GO:0060068)
0.0	0.0	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0009188	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.3	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.1	GO:0022011	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.2	GO:1902667	regulation of axon guidance(GO:1902667)
0.0	0.1	GO:0051797	positive regulation of hair cycle(GO:0042635) regulation of hair follicle development(GO:0051797) positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.0	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.2	GO:0031000	response to caffeine(GO:0031000)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.3	GO:0035195	gene silencing by miRNA(GO:0035195)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.2	GO:0006558	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.2	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0003309	type B pancreatic cell differentiation(GO:0003309)
0.0	0.1	GO:0085029	extracellular matrix assembly(GO:0085029)
0.0	0.0	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.0	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.3	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0051446	positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0032202	telomere assembly(GO:0032202)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.3	GO:0032006	regulation of TOR signaling(GO:0032006)
0.0	0.0	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892)
0.0	0.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0014911	positive regulation of smooth muscle cell migration(GO:0014911)
0.0	0.0	GO:0021826	substrate-independent telencephalic tangential migration(GO:0021826) substrate-independent telencephalic tangential interneuron migration(GO:0021843)
0.0	0.3	GO:0006662	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.1	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0006726	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) eye pigmentation(GO:0048069)
0.0	0.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.0	GO:0048311	mitochondrion distribution(GO:0048311)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.0	GO:0072217	negative regulation of metanephros development(GO:0072217) negative regulation of kidney development(GO:0090185)
0.0	0.0	GO:0060872	semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0042756	drinking behavior(GO:0042756)
0.0	0.0	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0090102	cochlea development(GO:0090102)
0.0	0.2	GO:0001502	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.2	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.2	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.1	GO:1904729	regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.0	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.0	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.2	GO:0009267	cellular response to starvation(GO:0009267)
0.0	0.0	GO:0046958	nonassociative learning(GO:0046958)
0.0	0.1	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.2	GO:0007405	neuroblast proliferation(GO:0007405)
0.0	0.0	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.2	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0010894	negative regulation of steroid biosynthetic process(GO:0010894)
0.0	0.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0006582	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0	0.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.0	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.2	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
0.0	0.0	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.0	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.0	0.1	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0072243	metanephric nephron tubule development(GO:0072234) metanephric nephron epithelium development(GO:0072243)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.0	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.0	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.0	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.0	GO:0010535	regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0	0.1	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.0	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.0	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.0	GO:0065005	protein-lipid complex assembly(GO:0065005)
0.0	0.1	GO:0007398	ectoderm development(GO:0007398)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.0	GO:0010224	response to UV-B(GO:0010224)
0.0	0.0	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.5	GO:0008584	male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0	0.0	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	0.0	GO:0015864	pyrimidine nucleoside transport(GO:0015864)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.2	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.3	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.3	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.4	GO:0071564	npBAF complex(GO:0071564)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.3	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.4	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.2	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.2	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.0	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.1	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.3	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.0	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.9	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.3	GO:0001533	cornified envelope(GO:0001533)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.4	GO:0031674	I band(GO:0031674)
0.0	0.0	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.0	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.9	GO:0060076	excitatory synapse(GO:0060076)
0.0	0.3	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.2	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.0	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	0.4	GO:0070052	collagen V binding(GO:0070052)
0.1	0.4	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.5	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.3	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1	0.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.7	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1	0.4	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.2	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1	0.3	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.1	0.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.3	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.2	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.8	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	0.4	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.2	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.2	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	0.4	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.2	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.3	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.3	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.3	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.5	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.5	GO:0043394	proteoglycan binding(GO:0043394)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.3	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.5	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.5	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.3	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.6	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.1	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.4	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.4	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.0	GO:0005497	androgen binding(GO:0005497)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.0	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0035240	dopamine binding(GO:0035240)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.3	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.0	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.0	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.1	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.0	0.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.2	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.0	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.0	GO:0030215	semaphorin receptor binding(GO:0030215)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.1	PID FGF PATHWAY	FGF signaling pathway
0.0	0.6	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.5	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.3	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.3	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.1	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.6	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	1.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.7	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.1	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.2	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.2	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation

Results for OLIG2_NEUROD1_ATOH1

Z-value: 1.26

Motif logo

Transcription factors associated with OLIG2_NEUROD1_ATOH1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the OLIG2_NEUROD1_ATOH1 motif across conditions

Conditions sorted by the z-value of the OLIG2_NEUROD1_ATOH1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG2_NEUROD1_ATOH1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: