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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for OSR1_OSR2

Z-value: 1.51

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Transcription factors associated with OSR1_OSR2

Gene Symbol	Gene ID	Gene Info
OSR1 Ensembl NCBI GeneCards UniProt	ENSG00000143867.5	odd-skipped related transcription factor 1
OSR2 Ensembl NCBI GeneCards UniProt	ENSG00000164920.5	odd-skipped related transciption factor 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_19558832_19558983	OSR1	493	0.853412	-0.92	5.1e-04	Click!
chr2_19557855_19558307	OSR1	333	0.918165	-0.89	1.2e-03	Click!
chr2_19557535_19557807	OSR1	743	0.740095	-0.88	1.8e-03	Click!
chr2_19738772_19738923	OSR1	180433	0.031599	-0.82	6.7e-03	Click!
chr2_19557319_19557513	OSR1	739	0.741579	-0.78	1.3e-02	Click!
chr8_99960836_99961034	OSR2	315	0.881682	-0.96	5.0e-05	Click!
chr8_99959447_99959598	OSR2	928	0.540225	-0.90	1.0e-03	Click!
chr8_99958037_99958188	OSR2	1225	0.421147	-0.90	1.0e-03	Click!
chr8_99959761_99960031	OSR2	554	0.739869	-0.89	1.2e-03	Click!
chr8_99961674_99961862	OSR2	1148	0.462619	-0.88	1.5e-03	Click!

Activity of the OSR1_OSR2 motif across conditions

Conditions sorted by the z-value of the OSR1_OSR2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr14_93120741_93121126	1.56	RIN3	Ras and Rab interactor 3	2087	0.42
chr1_167416841_167417022	1.34	RP11-104L21.2		10967	0.21
chr21_46341026_46341213	1.15	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	71	0.56
chr11_118094529_118095128	1.15	AMICA1	adhesion molecule, interacts with CXADR antigen 1	26	0.97
chr1_206644983_206645179	1.07	IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	1243	0.39
chr3_50647795_50648029	1.00	CISH	cytokine inducible SH2-containing protein	1291	0.31
chr3_46995163_46995374	0.95	CCDC12	coiled-coil domain containing 12	23002	0.14
chr21_32558355_32558506	0.91	TIAM1	T-cell lymphoma invasion and metastasis 1	55891	0.16
chr13_24826594_24826745	0.89	SPATA13	spermatogenesis associated 13	813	0.56
chr1_12227882_12228546	0.88	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	1154	0.44
chrX_133306946_133307220	0.84	ENSG00000207602	.	2775	0.12
chr4_78775368_78775519	0.82	MRPL1	mitochondrial ribosomal protein L1	8231	0.26
chr17_38019635_38019786	0.79	IKZF3	IKAROS family zinc finger 3 (Aiolos)	669	0.62
chr12_3979327_3979799	0.79	RP11-664D1.1		1337	0.47
chr13_75900551_75900966	0.79	TBC1D4	TBC1 domain family, member 4	14909	0.24
chr2_240188602_240189192	0.76	ENSG00000265215	.	38260	0.14
chr3_71438931_71439395	0.76	FOXP1	forkhead box P1	85252	0.09
chr10_7526466_7526625	0.75	ENSG00000207453	.	2226	0.38
chr1_112016807_112017159	0.75	C1orf162	chromosome 1 open reading frame 162	492	0.65
chr1_161185751_161185902	0.74	FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	739	0.37
chrX_153188624_153188806	0.74	ARHGAP4	Rho GTPase activating protein 4	1014	0.33
chrX_71322682_71322935	0.71	RGAG4	retrotransposon gag domain containing 4	28870	0.14
chr8_59717634_59717850	0.71	ENSG00000201231	.	9369	0.29
chr12_112439484_112439691	0.68	TMEM116	transmembrane protein 116	4202	0.19
chr8_61821706_61823076	0.68	RP11-33I11.2		100226	0.08
chr14_38547457_38547608	0.67	CTD-2058B24.2		12831	0.26
chr10_30818195_30818576	0.67	ENSG00000239744	.	26448	0.21
chr5_100239849_100240360	0.67	ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	1134	0.65
chrX_40430227_40430433	0.66	ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2	9816	0.21
chr14_22962722_22962873	0.66	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	6626	0.11
chr14_105531321_105531563	0.66	GPR132	G protein-coupled receptor 132	325	0.89
chr1_241840893_241841044	0.65	WDR64	WD repeat domain 64	5914	0.23
chr16_89041933_89042084	0.64	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	1393	0.37
chr3_186743256_186743535	0.64	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	124	0.97
chr6_167461201_167461401	0.64	FGFR1OP	FGFR1 oncogene partner	48405	0.1
chr7_150264558_150265605	0.63	GIMAP4	GTPase, IMAP family member 4	557	0.78
chr2_68994473_68994840	0.63	ARHGAP25	Rho GTPase activating protein 25	7277	0.25
chr17_43302327_43302665	0.63	CTD-2020K17.1		2907	0.13
chr20_56193926_56194226	0.63	ZBP1	Z-DNA binding protein 1	1374	0.49
chr3_112693608_112694254	0.62	CD200R1	CD200 receptor 1	6	0.97
chr5_133454026_133454256	0.62	TCF7	transcription factor 7 (T-cell specific, HMG-box)	2825	0.3
chr1_203277577_203277825	0.62	BTG2	BTG family, member 2	3037	0.23
chr17_53343669_53343820	0.61	HLF	hepatic leukemia factor	161	0.97
chr16_85569617_85569804	0.60	GSE1	Gse1 coiled-coil protein	75305	0.09
chr12_106673721_106673872	0.60	ENSG00000238609	.	2971	0.23
chr6_24934739_24934890	0.59	FAM65B	family with sequence similarity 65, member B	1374	0.5
chrX_11779384_11779693	0.59	MSL3	male-specific lethal 3 homolog (Drosophila)	1791	0.5
chr17_72739068_72739219	0.58	ENSG00000264624	.	5609	0.1
chrX_153233576_153233755	0.58	HCFC1-AS1	HCFC1 antisense RNA 1	1111	0.28
chr13_22154051_22154202	0.57	MICU2	mitochondrial calcium uptake 2	24194	0.17
chr3_16524138_16524319	0.57	RFTN1	raftlin, lipid raft linker 1	144	0.97
chr15_75078789_75078977	0.57	CSK	c-src tyrosine kinase	2002	0.19
chr17_78705219_78705370	0.57	RP11-28G8.1		74138	0.1
chr3_151922152_151922513	0.56	MBNL1	muscleblind-like splicing regulator 1	63497	0.12
chrX_70328307_70328586	0.56	IL2RG	interleukin 2 receptor, gamma	672	0.51
chr2_225503120_225503271	0.55	CUL3	cullin 3	53085	0.18
chr6_14857706_14857857	0.55	ENSG00000206960	.	211015	0.02
chr1_117148513_117148664	0.55	ENSG00000238532	.	13767	0.16
chr13_33002826_33002977	0.55	N4BP2L1	NEDD4 binding protein 2-like 1	586	0.77
chr5_32231564_32231715	0.55	ENSG00000199731	.	3342	0.27
chr10_24911603_24911839	0.54	ARHGAP21	Rho GTPase activating protein 21	42	0.98
chr20_52198141_52198292	0.54	ZNF217	zinc finger protein 217	1420	0.41
chr1_200995563_200995952	0.54	KIF21B	kinesin family member 21B	2929	0.25
chr11_121321680_121321831	0.54	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	1157	0.49
chr10_135202564_135202912	0.54	RP11-108K14.8	Mitochondrial GTPase 1	1600	0.18
chr6_133069333_133069484	0.54	RP1-55C23.7		4406	0.14
chr6_16131427_16131718	0.53	MYLIP	myosin regulatory light chain interacting protein	2170	0.29
chr7_63361181_63361806	0.53	ENSG00000263891	.	47	0.98
chrX_78408318_78408469	0.52	GPR174	G protein-coupled receptor 174	18076	0.3
chr2_240153040_240153235	0.52	HDAC4	histone deacetylase 4	40385	0.13
chr8_90985154_90985305	0.52	NBN	nibrin	8654	0.22
chr18_21598879_21599226	0.52	TTC39C	tetratricopeptide repeat domain 39C	2454	0.25
chr22_42177525_42177912	0.52	MEI1	meiosis inhibitor 1	21	0.96
chr14_52784712_52784898	0.52	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	3692	0.31
chr16_53403757_53403908	0.51	RP11-44F14.1		3163	0.23
chr14_71109663_71109962	0.51	TTC9	tetratricopeptide repeat domain 9	1308	0.48
chr11_117821485_117821636	0.51	TMPRSS13	transmembrane protease, serine 13	21386	0.15
chr5_95170588_95170973	0.51	GLRX	glutaredoxin (thioltransferase)	12071	0.13
chr15_74839026_74839177	0.50	ARID3B	AT rich interactive domain 3B (BRIGHT-like)	2410	0.26
chr18_13437944_13438095	0.50	LDLRAD4-AS1	LDLRAD4 antisense RNA 1	10540	0.12
chr13_99959249_99959863	0.50	GPR183	G protein-coupled receptor 183	103	0.97
chr12_111214509_111214660	0.50	PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	33840	0.16
chr9_95300214_95300365	0.49	ECM2	extracellular matrix protein 2, female organ and adipocyte specific	1352	0.42
chr1_160674269_160674421	0.49	CD48	CD48 molecule	7248	0.16
chr12_9821284_9821435	0.49	CLEC2D	C-type lectin domain family 2, member D	950	0.44
chr14_91877707_91877858	0.49	CCDC88C	coiled-coil domain containing 88C	5908	0.26
chr4_156655817_156655968	0.49	RP11-588K22.2		292	0.92
chr6_27106968_27108062	0.49	HIST1H4I	histone cluster 1, H4i	439	0.71
chr9_101881949_101882181	0.49	TGFBR1	transforming growth factor, beta receptor 1	7992	0.21
chrX_118924681_118925547	0.48	RPL39	ribosomal protein L39	492	0.74
chr7_18330156_18330333	0.48	HDAC9	histone deacetylase 9	199	0.96
chr22_45073265_45073416	0.48	PRR5	proline rich 5 (renal)	375	0.88
chr15_81590554_81590826	0.48	IL16	interleukin 16	1067	0.54
chr14_69328469_69328679	0.48	ENSG00000263694	.	16055	0.2
chr17_28087229_28087445	0.48	RP11-82O19.1		784	0.6
chr8_38216839_38216990	0.47	WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	21425	0.11
chr19_3183746_3183954	0.47	NCLN	nicalin	1711	0.25
chr13_41579232_41579390	0.47	ELF1	E74-like factor 1 (ets domain transcription factor)	14139	0.19
chr20_24932519_24932670	0.47	CST7	cystatin F (leukocystatin)	2728	0.28
chr12_28529916_28530067	0.47	ENSG00000252237	.	57595	0.14
chr5_159894836_159895683	0.46	ENSG00000265237	.	6150	0.17
chr9_92031550_92031701	0.46	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	2123	0.39
chr3_16550538_16550689	0.46	RFTN1	raftlin, lipid raft linker 1	3798	0.32
chr1_84609962_84610447	0.46	PRKACB	protein kinase, cAMP-dependent, catalytic, beta	250	0.95
chr7_26952596_26952747	0.46	SKAP2	src kinase associated phosphoprotein 2	48309	0.14
chr17_36716041_36716192	0.45	SRCIN1	SRC kinase signaling inhibitor 1	3544	0.2
chr10_73531555_73531706	0.45	C10orf54	chromosome 10 open reading frame 54	1625	0.38
chr2_232410055_232410615	0.45	NMUR1	neuromedin U receptor 1	15129	0.14
chr13_49684453_49685468	0.45	FNDC3A	fibronectin type III domain containing 3A	511	0.82
chr2_64978532_64979299	0.45	ENSG00000253082	.	24323	0.19
chr13_21050204_21050392	0.45	ENSG00000263978	.	42313	0.15
chr10_120891057_120891670	0.44	FAM45A	family with sequence similarity 45, member A	27734	0.11
chr18_33196853_33197169	0.44	RP11-712P20.2		21146	0.21
chr12_3827507_3827658	0.44	ENSG00000222338	.	7911	0.25
chr7_150435640_150435791	0.44	GIMAP5	GTPase, IMAP family member 5	1279	0.41
chr10_116063923_116064706	0.43	VWA2	von Willebrand factor A domain containing 2	65225	0.11
chr17_78738918_78739289	0.43	RP11-28G8.1		40329	0.17
chr19_19562496_19562686	0.43	GATAD2A	GATA zinc finger domain containing 2A	5330	0.15
chr2_204774247_204774560	0.43	ICOS	inducible T-cell co-stimulator	27068	0.21
chr12_6901564_6902297	0.43	CD4	CD4 molecule	3196	0.1
chr21_19161404_19161758	0.43	AL109761.5		4224	0.27
chr5_68608223_68608374	0.42	CCDC125	coiled-coil domain containing 125	8112	0.18
chr5_67539405_67539715	0.42	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	3834	0.32
chr15_75069286_75069492	0.42	CSK	c-src tyrosine kinase	5009	0.13
chr19_19292427_19292578	0.42	MEF2BNB	MEF2B neighbor	4405	0.11
chr1_8683722_8683873	0.42	RERE	arginine-glutamic acid dipeptide (RE) repeats	642	0.8
chr13_41556565_41556847	0.42	ELF1	E74-like factor 1 (ets domain transcription factor)	288	0.92
chr1_207094320_207094619	0.42	FAIM3	Fas apoptotic inhibitory molecule 3	743	0.59
chr19_7722364_7722515	0.42	RETN	resistin	11491	0.07
chr11_397386_397537	0.41	PKP3	plakophilin 3	3218	0.12
chr11_34360366_34360517	0.41	ABTB2	ankyrin repeat and BTB (POZ) domain containing 2	18361	0.25
chrX_19814210_19814361	0.41	SH3KBP1	SH3-domain kinase binding protein 1	3584	0.36
chr13_41372571_41372761	0.41	SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	5372	0.18
chr6_155635765_155636118	0.40	TFB1M	transcription factor B1, mitochondrial	323	0.92
chr19_17295350_17295501	0.40	CTD-3032J10.4		6140	0.1
chr18_8441840_8441991	0.40	ENSG00000242985	.	29914	0.14
chr1_112165916_112166067	0.40	RAP1A	RAP1A, member of RAS oncogene family	3222	0.23
chr1_158901311_158901684	0.40	PYHIN1	pyrin and HIN domain family, member 1	139	0.97
chrX_49125842_49126050	0.40	PPP1R3F	protein phosphatase 1, regulatory subunit 3F	360	0.74
chr6_25040660_25040811	0.40	RP3-425P12.5		1332	0.34
chr14_22992791_22992997	0.40	TRAJ15	T cell receptor alpha joining 15	5686	0.12
chr16_28505762_28506015	0.39	APOBR	apolipoprotein B receptor	82	0.93
chr12_51719066_51719217	0.39	BIN2	bridging integrator 2	689	0.64
chr19_44037034_44037583	0.39	ZNF575	zinc finger protein 575	48	0.95
chr15_63783060_63783211	0.39	USP3	ubiquitin specific peptidase 3	13658	0.23
chr20_34355873_34356204	0.39	ENSG00000222152	.	1751	0.25
chr12_7060685_7060854	0.39	PTPN6	protein tyrosine phosphatase, non-receptor type 6	231	0.78
chr11_64036844_64037358	0.39	GPR137	G protein-coupled receptor 137	433	0.56
chr2_26678962_26679113	0.39	DRC1	dynein regulatory complex subunit 1 homolog (Chlamydomonas)	7870	0.21
chr3_186288875_186289450	0.38	DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	695	0.44
chr16_30583519_30583791	0.38	ZNF688	zinc finger protein 688	73	0.49
chr21_36417015_36417237	0.38	RUNX1	runt-related transcription factor 1	4336	0.37
chr12_125052371_125052867	0.38	NCOR2	nuclear receptor corepressor 2	609	0.84
chr5_150614646_150614797	0.38	CCDC69	coiled-coil domain containing 69	11015	0.18
chr3_160689400_160689551	0.38	PPM1L	protein phosphatase, Mg2+/Mn2+ dependent, 1L	129460	0.05
chrX_78420022_78420173	0.38	GPR174	G protein-coupled receptor 174	6372	0.34
chr7_50351765_50352753	0.38	IKZF1	IKAROS family zinc finger 1 (Ikaros)	3941	0.34
chr1_55677917_55678072	0.37	USP24	ubiquitin specific peptidase 24	2768	0.31
chr9_134150778_134151758	0.37	FAM78A	family with sequence similarity 78, member A	666	0.69
chr3_156298867_156299018	0.37	SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)	25969	0.2
chr6_138280285_138280436	0.37	RP11-356I2.4		90990	0.08
chr3_196351172_196351376	0.37	LINC01063	long intergenic non-protein coding RNA 1063	8184	0.13
chr8_19537436_19537587	0.37	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	2583	0.42
chr9_2022394_2022545	0.37	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	524	0.84
chr1_167485436_167485587	0.37	CD247	CD247 molecule	2264	0.32
chr5_35857058_35857643	0.37	IL7R	interleukin 7 receptor	356	0.89
chr1_207496793_207497173	0.37	CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	1847	0.46
chr1_168390803_168391087	0.37	ENSG00000207974	.	46183	0.16
chr20_56055852_56056003	0.37	CTCFL	CCCTC-binding factor (zinc finger protein)-like	43386	0.13
chr2_48541107_48541379	0.37	FOXN2	forkhead box N2	533	0.82
chr5_137548291_137548968	0.37	CDC23	cell division cycle 23	383	0.81
chr20_34329591_34330097	0.37	RBM39	RNA binding motif protein 39	29	0.96
chr6_149639720_149640661	0.37	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	754	0.68
chr22_26986275_26986603	0.37	TPST2	tyrosylprotein sulfotransferase 2	312	0.88
chr10_130834757_130834924	0.37	MGMT	O-6-methylguanine-DNA methyltransferase	430608	0.01
chr2_113589546_113589712	0.36	IL1B	interleukin 1, beta	4382	0.19
chrX_131156430_131156597	0.36	MST4	Serine/threonine-protein kinase MST4	780	0.69
chr21_36217976_36218127	0.36	RUNX1	runt-related transcription factor 1	41429	0.2
chr8_133770966_133771357	0.36	TMEM71	transmembrane protein 71	1633	0.38
chr12_105076421_105076798	0.36	ENSG00000264295	.	91198	0.08
chr11_88148240_88148545	0.36	CTSC	cathepsin C	77437	0.11
chr14_68286245_68286488	0.36	RAD51B	RAD51 paralog B	130	0.96
chr19_2074395_2074546	0.36	MOB3A	MOB kinase activator 3A	4248	0.13
chr10_101943124_101943275	0.36	ERLIN1	ER lipid raft associated 1	2587	0.2
chr7_26414710_26414861	0.36	AC004540.4		1107	0.56
chr1_158979847_158980361	0.36	IFI16	interferon, gamma-inducible protein 16	304	0.91
chr16_84648994_84649167	0.35	COTL1	coactosin-like 1 (Dictyostelium)	2585	0.25
chr5_118604468_118605539	0.35	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	554	0.77
chr3_59996431_59996582	0.35	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	38923	0.24
chrX_78409666_78409817	0.35	GPR174	G protein-coupled receptor 174	16728	0.3
chr15_52513371_52513623	0.35	GNB5	guanine nucleotide binding protein (G protein), beta 5	29931	0.15
chr3_186745077_186745229	0.35	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	1882	0.42
chr1_108331508_108331671	0.35	ENSG00000265536	.	12711	0.25
chr6_35279100_35279566	0.35	DEF6	differentially expressed in FDCP 6 homolog (mouse)	1818	0.34
chr20_33102938_33103232	0.35	DYNLRB1	dynein, light chain, roadblock-type 1	1129	0.43
chr2_205920685_205921182	0.35	PARD3B	par-3 family cell polarity regulator beta	510210	0.0
chr4_77226594_77226879	0.35	FAM47E-STBD1	FAM47E-STBD1 readthrough	443	0.83
chr1_29254208_29254684	0.35	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	13355	0.18
chr9_95055581_95055984	0.34	IARS	isoleucyl-tRNA synthetase	141	0.91
chr2_198379866_198380021	0.34	MOB4	MOB family member 4, phocein	352	0.79

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of OSR1_OSR2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.2	0.6	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.5	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.7	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.6	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.8	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.3	GO:0001821	histamine secretion(GO:0001821)
0.1	0.2	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.1	0.1	GO:0019042	viral latency(GO:0019042)
0.1	0.5	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.1	0.3	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.3	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.1	0.3	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.2	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.3	GO:0014805	smooth muscle adaptation(GO:0014805)
0.1	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.2	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.1	0.6	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.3	GO:2000319	T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1	0.2	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.3	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.1	0.5	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.2	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1	0.2	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.4	GO:0043368	positive T cell selection(GO:0043368)
0.1	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.3	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.5	GO:0007141	male meiosis I(GO:0007141)
0.1	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.3	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.2	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0010586	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.3	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0010224	response to UV-B(GO:0010224)
0.0	0.3	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.0	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.0	0.2	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	1.1	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.0	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) negative regulation of lipoprotein particle clearance(GO:0010985)
0.0	0.1	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.2	GO:0050685	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.2	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.1	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.2	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	1.0	GO:0030593	neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.0	0.4	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)
0.0	0.2	GO:0006273	lagging strand elongation(GO:0006273)
0.0	0.0	GO:0070391	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.1	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.3	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.2	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.1	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.2	GO:0060023	soft palate development(GO:0060023)
0.0	0.3	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.4	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.1	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.2	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.0	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.1	GO:0071027	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.5	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.3	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.2	GO:0000018	regulation of DNA recombination(GO:0000018)
0.0	0.4	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.2	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.4	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.2	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.2	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:1904063	negative regulation of cation transmembrane transport(GO:1904063)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.3	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.3	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.6	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.3	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.6	GO:0046464	neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0	0.2	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.3	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.2	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.2	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.1	GO:0046634	regulation of alpha-beta T cell activation(GO:0046634)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.5	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.0	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0002467	germinal center formation(GO:0002467)
0.0	0.2	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.0	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.0	0.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.3	GO:0075733	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.0	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.2	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.2	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.5	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.0	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.5	GO:0001906	cell killing(GO:0001906)
0.0	0.0	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.0	GO:0001743	optic placode formation(GO:0001743)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.4	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.9	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0	0.4	GO:0016064	immunoglobulin mediated immune response(GO:0016064) B cell mediated immunity(GO:0019724)
0.0	0.2	GO:0016045	detection of bacterium(GO:0016045)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0060058	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.2	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.0	0.0	GO:0051136	NK T cell differentiation(GO:0001865) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.5	GO:0007632	visual behavior(GO:0007632)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.4	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.0	GO:0051709	regulation of killing of cells of other organism(GO:0051709) positive regulation of killing of cells of other organism(GO:0051712)
0.0	0.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:1904376	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0032239	regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.0	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	1.3	GO:0006959	humoral immune response(GO:0006959)
0.0	0.1	GO:0030147	obsolete natriuresis(GO:0030147)
0.0	0.1	GO:0033081	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.0	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.0	GO:0060292	long term synaptic depression(GO:0060292)
0.0	0.0	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.0	GO:0042508	tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.0	0.0	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.0	GO:0002820	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0002579	positive regulation of antigen processing and presentation(GO:0002579) positive regulation of dendritic cell antigen processing and presentation(GO:0002606) interleukin-3 production(GO:0032632)
0.0	0.1	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.0	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.0	GO:0010225	response to UV-C(GO:0010225)
0.0	0.0	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.0	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.3	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.8	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.2	GO:0042770	signal transduction in response to DNA damage(GO:0042770)
0.0	0.2	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.4	GO:0000216	obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0	0.0	GO:0032604	granulocyte macrophage colony-stimulating factor production(GO:0032604) regulation of granulocyte macrophage colony-stimulating factor production(GO:0032645)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.9	GO:0044783	mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
0.0	2.0	GO:0050776	regulation of immune response(GO:0050776)
0.0	0.0	GO:0002092	positive regulation of receptor internalization(GO:0002092)
0.0	0.2	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.6	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.0	GO:2000757	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.0	GO:0002320	lymphoid progenitor cell differentiation(GO:0002320) pro-B cell differentiation(GO:0002328)
0.0	0.2	GO:0051225	spindle assembly(GO:0051225)
0.0	0.2	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.0	GO:0060760	positive regulation of response to cytokine stimulus(GO:0060760)
0.0	0.0	GO:0044252	negative regulation of collagen metabolic process(GO:0010713) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.0	0.1	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0040034	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.0	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.0	GO:0032479	regulation of type I interferon production(GO:0032479)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:1901998	antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.0	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.3	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.2	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.0	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.4	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.0	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.0	GO:0090559	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.2	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.6	GO:0000082	G1/S transition of mitotic cell cycle(GO:0000082) cell cycle G1/S phase transition(GO:0044843)
0.0	0.0	GO:0045006	DNA deamination(GO:0045006)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.0	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0	0.1	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.0	GO:0001820	serotonin secretion(GO:0001820)
0.0	0.0	GO:0031057	negative regulation of histone modification(GO:0031057)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:1905037	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.0	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0000050	urea cycle(GO:0000050)
0.0	0.0	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.0	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.0	0.0	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.0	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.4	GO:0016571	histone methylation(GO:0016571)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.0	0.7	GO:0006338	chromatin remodeling(GO:0006338)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0030225	macrophage differentiation(GO:0030225)
0.0	0.1	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.1	GO:0006929	substrate-dependent cell migration(GO:0006929)
0.0	0.3	GO:0072512	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.0	GO:0032735	positive regulation of interleukin-12 production(GO:0032735)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0000154	rRNA modification(GO:0000154)
0.0	0.0	GO:1902743	regulation of lamellipodium organization(GO:1902743)
0.0	0.2	GO:0018410	C-terminal protein amino acid modification(GO:0018410)
0.0	0.0	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0050686	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.0	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.0	0.1	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
0.0	0.0	GO:0045060	negative thymic T cell selection(GO:0045060)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.4	GO:0072487	MSL complex(GO:0072487)
0.1	0.6	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.5	GO:0070688	MLL5-L complex(GO:0070688)
0.1	0.3	GO:0071778	obsolete WINAC complex(GO:0071778)
0.1	0.2	GO:0005827	polar microtubule(GO:0005827)
0.1	0.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	0.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.2	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.3	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.3	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.0	GO:0033391	chromatoid body(GO:0033391)
0.0	1.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.5	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	1.2	GO:0034708	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.8	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.4	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.9	GO:0030175	filopodium(GO:0030175)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.7	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.4	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.7	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.5	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.9	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	1.1	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.0	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.0	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.3	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.2	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.5	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.1	GO:0001772	immunological synapse(GO:0001772)
0.0	2.6	GO:0016604	nuclear body(GO:0016604)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0000346	transcription export complex(GO:0000346)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.2	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.6	GO:0055037	recycling endosome(GO:0055037)
0.0	0.0	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.3	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.3	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	1.0	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.2	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.6	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.0	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0008384	IkappaB kinase activity(GO:0008384)
0.1	0.4	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.4	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.3	GO:0019863	IgE binding(GO:0019863)
0.1	0.4	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.4	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.1	1.3	GO:0070491	repressing transcription factor binding(GO:0070491)
0.1	0.3	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1	0.5	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.5	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.5	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.3	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1	0.2	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	0.2	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.1	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	1.4	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.2	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.2	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1	0.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.8	GO:0008373	sialyltransferase activity(GO:0008373)
0.1	0.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.2	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.4	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.4	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.5	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.5	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.2	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.2	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	1.3	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.4	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0046979	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.0	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.7	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.3	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.0	GO:0005035	death receptor activity(GO:0005035)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.0	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.4	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0035586	G-protein coupled adenosine receptor activity(GO:0001609) purinergic receptor activity(GO:0035586)
0.0	0.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.3	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.3	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.6	GO:0019210	kinase inhibitor activity(GO:0019210)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.0	GO:0033265	choline binding(GO:0033265)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.5	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.0	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.5	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.0	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.5	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.0	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.3	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.0	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.0	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.0	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.0	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.0	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.0	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
0.0	0.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.3	GO:0042393	histone binding(GO:0042393)
0.0	0.4	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.1	GO:0050664	superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.2	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.0	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.0	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	0.8	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	0.5	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	1.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	3.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.7	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	1.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.8	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.6	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.7	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.6	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.6	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.7	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.3	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.6	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.3	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.4	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.0	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.5	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.2	PID MYC PATHWAY	C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	0.3	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	0.2	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	3.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	0.8	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	0.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.6	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.5	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.4	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	1.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	1.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.0	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0	0.2	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.8	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.1	REACTOME ORC1 REMOVAL FROM CHROMATIN	Genes involved in Orc1 removal from chromatin
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.3	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.3	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.6	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.0	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.0	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex

Results for OSR1_OSR2

Z-value: 1.51

Motif logo

Transcription factors associated with OSR1_OSR2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the OSR1_OSR2 motif across conditions

Conditions sorted by the z-value of the OSR1_OSR2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of OSR1_OSR2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: