Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for OSR1_OSR2

Z-value: 1.51

Motif logo

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Transcription factors associated with OSR1_OSR2

Gene Symbol Gene ID Gene Info
ENSG00000143867.5 OSR1
ENSG00000164920.5 OSR2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
OSR1chr2_19558832_195589834930.853412-0.925.1e-04Click!
OSR1chr2_19557855_195583073330.918165-0.891.2e-03Click!
OSR1chr2_19557535_195578077430.740095-0.881.8e-03Click!
OSR1chr2_19738772_197389231804330.031599-0.826.7e-03Click!
OSR1chr2_19557319_195575137390.741579-0.781.3e-02Click!
OSR2chr8_99960836_999610343150.881682-0.965.0e-05Click!
OSR2chr8_99959447_999595989280.540225-0.901.0e-03Click!
OSR2chr8_99958037_9995818812250.421147-0.901.0e-03Click!
OSR2chr8_99959761_999600315540.739869-0.891.2e-03Click!
OSR2chr8_99961674_9996186211480.462619-0.881.5e-03Click!

Activity of the OSR1_OSR2 motif across conditions

Conditions sorted by the z-value of the OSR1_OSR2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_93120741_93121126 1.56 RIN3
Ras and Rab interactor 3
2087
0.42
chr1_167416841_167417022 1.34 RP11-104L21.2

10967
0.21
chr21_46341026_46341213 1.15 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
71
0.56
chr11_118094529_118095128 1.15 AMICA1
adhesion molecule, interacts with CXADR antigen 1
26
0.97
chr1_206644983_206645179 1.07 IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
1243
0.39
chr3_50647795_50648029 1.00 CISH
cytokine inducible SH2-containing protein
1291
0.31
chr3_46995163_46995374 0.95 CCDC12
coiled-coil domain containing 12
23002
0.14
chr21_32558355_32558506 0.91 TIAM1
T-cell lymphoma invasion and metastasis 1
55891
0.16
chr13_24826594_24826745 0.89 SPATA13
spermatogenesis associated 13
813
0.56
chr1_12227882_12228546 0.88 TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
1154
0.44
chrX_133306946_133307220 0.84 ENSG00000207602
.
2775
0.12
chr4_78775368_78775519 0.82 MRPL1
mitochondrial ribosomal protein L1
8231
0.26
chr17_38019635_38019786 0.79 IKZF3
IKAROS family zinc finger 3 (Aiolos)
669
0.62
chr12_3979327_3979799 0.79 RP11-664D1.1

1337
0.47
chr13_75900551_75900966 0.79 TBC1D4
TBC1 domain family, member 4
14909
0.24
chr2_240188602_240189192 0.76 ENSG00000265215
.
38260
0.14
chr3_71438931_71439395 0.76 FOXP1
forkhead box P1
85252
0.09
chr10_7526466_7526625 0.75 ENSG00000207453
.
2226
0.38
chr1_112016807_112017159 0.75 C1orf162
chromosome 1 open reading frame 162
492
0.65
chr1_161185751_161185902 0.74 FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
739
0.37
chrX_153188624_153188806 0.74 ARHGAP4
Rho GTPase activating protein 4
1014
0.33
chrX_71322682_71322935 0.71 RGAG4
retrotransposon gag domain containing 4
28870
0.14
chr8_59717634_59717850 0.71 ENSG00000201231
.
9369
0.29
chr12_112439484_112439691 0.68 TMEM116
transmembrane protein 116
4202
0.19
chr8_61821706_61823076 0.68 RP11-33I11.2

100226
0.08
chr14_38547457_38547608 0.67 CTD-2058B24.2

12831
0.26
chr10_30818195_30818576 0.67 ENSG00000239744
.
26448
0.21
chr5_100239849_100240360 0.67 ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
1134
0.65
chrX_40430227_40430433 0.66 ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
9816
0.21
chr14_22962722_22962873 0.66 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
6626
0.11
chr14_105531321_105531563 0.66 GPR132
G protein-coupled receptor 132
325
0.89
chr1_241840893_241841044 0.65 WDR64
WD repeat domain 64
5914
0.23
chr16_89041933_89042084 0.64 CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
1393
0.37
chr3_186743256_186743535 0.64 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
124
0.97
chr6_167461201_167461401 0.64 FGFR1OP
FGFR1 oncogene partner
48405
0.1
chr7_150264558_150265605 0.63 GIMAP4
GTPase, IMAP family member 4
557
0.78
chr2_68994473_68994840 0.63 ARHGAP25
Rho GTPase activating protein 25
7277
0.25
chr17_43302327_43302665 0.63 CTD-2020K17.1

2907
0.13
chr20_56193926_56194226 0.63 ZBP1
Z-DNA binding protein 1
1374
0.49
chr3_112693608_112694254 0.62 CD200R1
CD200 receptor 1
6
0.97
chr5_133454026_133454256 0.62 TCF7
transcription factor 7 (T-cell specific, HMG-box)
2825
0.3
chr1_203277577_203277825 0.62 BTG2
BTG family, member 2
3037
0.23
chr17_53343669_53343820 0.61 HLF
hepatic leukemia factor
161
0.97
chr16_85569617_85569804 0.60 GSE1
Gse1 coiled-coil protein
75305
0.09
chr12_106673721_106673872 0.60 ENSG00000238609
.
2971
0.23
chr6_24934739_24934890 0.59 FAM65B
family with sequence similarity 65, member B
1374
0.5
chrX_11779384_11779693 0.59 MSL3
male-specific lethal 3 homolog (Drosophila)
1791
0.5
chr17_72739068_72739219 0.58 ENSG00000264624
.
5609
0.1
chrX_153233576_153233755 0.58 HCFC1-AS1
HCFC1 antisense RNA 1
1111
0.28
chr13_22154051_22154202 0.57 MICU2
mitochondrial calcium uptake 2
24194
0.17
chr3_16524138_16524319 0.57 RFTN1
raftlin, lipid raft linker 1
144
0.97
chr15_75078789_75078977 0.57 CSK
c-src tyrosine kinase
2002
0.19
chr17_78705219_78705370 0.57 RP11-28G8.1

74138
0.1
chr3_151922152_151922513 0.56 MBNL1
muscleblind-like splicing regulator 1
63497
0.12
chrX_70328307_70328586 0.56 IL2RG
interleukin 2 receptor, gamma
672
0.51
chr2_225503120_225503271 0.55 CUL3
cullin 3
53085
0.18
chr6_14857706_14857857 0.55 ENSG00000206960
.
211015
0.02
chr1_117148513_117148664 0.55 ENSG00000238532
.
13767
0.16
chr13_33002826_33002977 0.55 N4BP2L1
NEDD4 binding protein 2-like 1
586
0.77
chr5_32231564_32231715 0.55 ENSG00000199731
.
3342
0.27
chr10_24911603_24911839 0.54 ARHGAP21
Rho GTPase activating protein 21
42
0.98
chr20_52198141_52198292 0.54 ZNF217
zinc finger protein 217
1420
0.41
chr1_200995563_200995952 0.54 KIF21B
kinesin family member 21B
2929
0.25
chr11_121321680_121321831 0.54 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
1157
0.49
chr10_135202564_135202912 0.54 RP11-108K14.8
Mitochondrial GTPase 1
1600
0.18
chr6_133069333_133069484 0.54 RP1-55C23.7

4406
0.14
chr6_16131427_16131718 0.53 MYLIP
myosin regulatory light chain interacting protein
2170
0.29
chr7_63361181_63361806 0.53 ENSG00000263891
.
47
0.98
chrX_78408318_78408469 0.52 GPR174
G protein-coupled receptor 174
18076
0.3
chr2_240153040_240153235 0.52 HDAC4
histone deacetylase 4
40385
0.13
chr8_90985154_90985305 0.52 NBN
nibrin
8654
0.22
chr18_21598879_21599226 0.52 TTC39C
tetratricopeptide repeat domain 39C
2454
0.25
chr22_42177525_42177912 0.52 MEI1
meiosis inhibitor 1
21
0.96
chr14_52784712_52784898 0.52 PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
3692
0.31
chr16_53403757_53403908 0.51 RP11-44F14.1

3163
0.23
chr14_71109663_71109962 0.51 TTC9
tetratricopeptide repeat domain 9
1308
0.48
chr11_117821485_117821636 0.51 TMPRSS13
transmembrane protease, serine 13
21386
0.15
chr5_95170588_95170973 0.51 GLRX
glutaredoxin (thioltransferase)
12071
0.13
chr15_74839026_74839177 0.50 ARID3B
AT rich interactive domain 3B (BRIGHT-like)
2410
0.26
chr18_13437944_13438095 0.50 LDLRAD4-AS1
LDLRAD4 antisense RNA 1
10540
0.12
chr13_99959249_99959863 0.50 GPR183
G protein-coupled receptor 183
103
0.97
chr12_111214509_111214660 0.50 PPP1CC
protein phosphatase 1, catalytic subunit, gamma isozyme
33840
0.16
chr9_95300214_95300365 0.49 ECM2
extracellular matrix protein 2, female organ and adipocyte specific
1352
0.42
chr1_160674269_160674421 0.49 CD48
CD48 molecule
7248
0.16
chr12_9821284_9821435 0.49 CLEC2D
C-type lectin domain family 2, member D
950
0.44
chr14_91877707_91877858 0.49 CCDC88C
coiled-coil domain containing 88C
5908
0.26
chr4_156655817_156655968 0.49 RP11-588K22.2

292
0.92
chr6_27106968_27108062 0.49 HIST1H4I
histone cluster 1, H4i
439
0.71
chr9_101881949_101882181 0.49 TGFBR1
transforming growth factor, beta receptor 1
7992
0.21
chrX_118924681_118925547 0.48 RPL39
ribosomal protein L39
492
0.74
chr7_18330156_18330333 0.48 HDAC9
histone deacetylase 9
199
0.96
chr22_45073265_45073416 0.48 PRR5
proline rich 5 (renal)
375
0.88
chr15_81590554_81590826 0.48 IL16
interleukin 16
1067
0.54
chr14_69328469_69328679 0.48 ENSG00000263694
.
16055
0.2
chr17_28087229_28087445 0.48 RP11-82O19.1

784
0.6
chr8_38216839_38216990 0.47 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
21425
0.11
chr19_3183746_3183954 0.47 NCLN
nicalin
1711
0.25
chr13_41579232_41579390 0.47 ELF1
E74-like factor 1 (ets domain transcription factor)
14139
0.19
chr20_24932519_24932670 0.47 CST7
cystatin F (leukocystatin)
2728
0.28
chr12_28529916_28530067 0.47 ENSG00000252237
.
57595
0.14
chr5_159894836_159895683 0.46 ENSG00000265237
.
6150
0.17
chr9_92031550_92031701 0.46 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
2123
0.39
chr3_16550538_16550689 0.46 RFTN1
raftlin, lipid raft linker 1
3798
0.32
chr1_84609962_84610447 0.46 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
250
0.95
chr7_26952596_26952747 0.46 SKAP2
src kinase associated phosphoprotein 2
48309
0.14
chr17_36716041_36716192 0.45 SRCIN1
SRC kinase signaling inhibitor 1
3544
0.2
chr10_73531555_73531706 0.45 C10orf54
chromosome 10 open reading frame 54
1625
0.38
chr2_232410055_232410615 0.45 NMUR1
neuromedin U receptor 1
15129
0.14
chr13_49684453_49685468 0.45 FNDC3A
fibronectin type III domain containing 3A
511
0.82
chr2_64978532_64979299 0.45 ENSG00000253082
.
24323
0.19
chr13_21050204_21050392 0.45 ENSG00000263978
.
42313
0.15
chr10_120891057_120891670 0.44 FAM45A
family with sequence similarity 45, member A
27734
0.11
chr18_33196853_33197169 0.44 RP11-712P20.2

21146
0.21
chr12_3827507_3827658 0.44 ENSG00000222338
.
7911
0.25
chr7_150435640_150435791 0.44 GIMAP5
GTPase, IMAP family member 5
1279
0.41
chr10_116063923_116064706 0.43 VWA2
von Willebrand factor A domain containing 2
65225
0.11
chr17_78738918_78739289 0.43 RP11-28G8.1

40329
0.17
chr19_19562496_19562686 0.43 GATAD2A
GATA zinc finger domain containing 2A
5330
0.15
chr2_204774247_204774560 0.43 ICOS
inducible T-cell co-stimulator
27068
0.21
chr12_6901564_6902297 0.43 CD4
CD4 molecule
3196
0.1
chr21_19161404_19161758 0.43 AL109761.5

4224
0.27
chr5_68608223_68608374 0.42 CCDC125
coiled-coil domain containing 125
8112
0.18
chr5_67539405_67539715 0.42 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
3834
0.32
chr15_75069286_75069492 0.42 CSK
c-src tyrosine kinase
5009
0.13
chr19_19292427_19292578 0.42 MEF2BNB
MEF2B neighbor
4405
0.11
chr1_8683722_8683873 0.42 RERE
arginine-glutamic acid dipeptide (RE) repeats
642
0.8
chr13_41556565_41556847 0.42 ELF1
E74-like factor 1 (ets domain transcription factor)
288
0.92
chr1_207094320_207094619 0.42 FAIM3
Fas apoptotic inhibitory molecule 3
743
0.59
chr19_7722364_7722515 0.42 RETN
resistin
11491
0.07
chr11_397386_397537 0.41 PKP3
plakophilin 3
3218
0.12
chr11_34360366_34360517 0.41 ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
18361
0.25
chrX_19814210_19814361 0.41 SH3KBP1
SH3-domain kinase binding protein 1
3584
0.36
chr13_41372571_41372761 0.41 SLC25A15
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
5372
0.18
chr6_155635765_155636118 0.40 TFB1M
transcription factor B1, mitochondrial
323
0.92
chr19_17295350_17295501 0.40 CTD-3032J10.4

6140
0.1
chr18_8441840_8441991 0.40 ENSG00000242985
.
29914
0.14
chr1_112165916_112166067 0.40 RAP1A
RAP1A, member of RAS oncogene family
3222
0.23
chr1_158901311_158901684 0.40 PYHIN1
pyrin and HIN domain family, member 1
139
0.97
chrX_49125842_49126050 0.40 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
360
0.74
chr6_25040660_25040811 0.40 RP3-425P12.5

1332
0.34
chr14_22992791_22992997 0.40 TRAJ15
T cell receptor alpha joining 15
5686
0.12
chr16_28505762_28506015 0.39 APOBR
apolipoprotein B receptor
82
0.93
chr12_51719066_51719217 0.39 BIN2
bridging integrator 2
689
0.64
chr19_44037034_44037583 0.39 ZNF575
zinc finger protein 575
48
0.95
chr15_63783060_63783211 0.39 USP3
ubiquitin specific peptidase 3
13658
0.23
chr20_34355873_34356204 0.39 ENSG00000222152
.
1751
0.25
chr12_7060685_7060854 0.39 PTPN6
protein tyrosine phosphatase, non-receptor type 6
231
0.78
chr11_64036844_64037358 0.39 GPR137
G protein-coupled receptor 137
433
0.56
chr2_26678962_26679113 0.39 DRC1
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
7870
0.21
chr3_186288875_186289450 0.38 DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
695
0.44
chr16_30583519_30583791 0.38 ZNF688
zinc finger protein 688
73
0.49
chr21_36417015_36417237 0.38 RUNX1
runt-related transcription factor 1
4336
0.37
chr12_125052371_125052867 0.38 NCOR2
nuclear receptor corepressor 2
609
0.84
chr5_150614646_150614797 0.38 CCDC69
coiled-coil domain containing 69
11015
0.18
chr3_160689400_160689551 0.38 PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
129460
0.05
chrX_78420022_78420173 0.38 GPR174
G protein-coupled receptor 174
6372
0.34
chr7_50351765_50352753 0.38 IKZF1
IKAROS family zinc finger 1 (Ikaros)
3941
0.34
chr1_55677917_55678072 0.37 USP24
ubiquitin specific peptidase 24
2768
0.31
chr9_134150778_134151758 0.37 FAM78A
family with sequence similarity 78, member A
666
0.69
chr3_156298867_156299018 0.37 SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
25969
0.2
chr6_138280285_138280436 0.37 RP11-356I2.4

90990
0.08
chr3_196351172_196351376 0.37 LINC01063
long intergenic non-protein coding RNA 1063
8184
0.13
chr8_19537436_19537587 0.37 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
2583
0.42
chr9_2022394_2022545 0.37 SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
524
0.84
chr1_167485436_167485587 0.37 CD247
CD247 molecule
2264
0.32
chr5_35857058_35857643 0.37 IL7R
interleukin 7 receptor
356
0.89
chr1_207496793_207497173 0.37 CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
1847
0.46
chr1_168390803_168391087 0.37 ENSG00000207974
.
46183
0.16
chr20_56055852_56056003 0.37 CTCFL
CCCTC-binding factor (zinc finger protein)-like
43386
0.13
chr2_48541107_48541379 0.37 FOXN2
forkhead box N2
533
0.82
chr5_137548291_137548968 0.37 CDC23
cell division cycle 23
383
0.81
chr20_34329591_34330097 0.37 RBM39
RNA binding motif protein 39
29
0.96
chr6_149639720_149640661 0.37 TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
754
0.68
chr22_26986275_26986603 0.37 TPST2
tyrosylprotein sulfotransferase 2
312
0.88
chr10_130834757_130834924 0.37 MGMT
O-6-methylguanine-DNA methyltransferase
430608
0.01
chr2_113589546_113589712 0.36 IL1B
interleukin 1, beta
4382
0.19
chrX_131156430_131156597 0.36 MST4
Serine/threonine-protein kinase MST4
780
0.69
chr21_36217976_36218127 0.36 RUNX1
runt-related transcription factor 1
41429
0.2
chr8_133770966_133771357 0.36 TMEM71
transmembrane protein 71
1633
0.38
chr12_105076421_105076798 0.36 ENSG00000264295
.
91198
0.08
chr11_88148240_88148545 0.36 CTSC
cathepsin C
77437
0.11
chr14_68286245_68286488 0.36 RAD51B
RAD51 paralog B
130
0.96
chr19_2074395_2074546 0.36 MOB3A
MOB kinase activator 3A
4248
0.13
chr10_101943124_101943275 0.36 ERLIN1
ER lipid raft associated 1
2587
0.2
chr7_26414710_26414861 0.36 AC004540.4

1107
0.56
chr1_158979847_158980361 0.36 IFI16
interferon, gamma-inducible protein 16
304
0.91
chr16_84648994_84649167 0.35 COTL1
coactosin-like 1 (Dictyostelium)
2585
0.25
chr5_118604468_118605539 0.35 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
554
0.77
chr3_59996431_59996582 0.35 NPCDR1
nasopharyngeal carcinoma, down-regulated 1
38923
0.24
chrX_78409666_78409817 0.35 GPR174
G protein-coupled receptor 174
16728
0.3
chr15_52513371_52513623 0.35 GNB5
guanine nucleotide binding protein (G protein), beta 5
29931
0.15
chr3_186745077_186745229 0.35 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
1882
0.42
chr1_108331508_108331671 0.35 ENSG00000265536
.
12711
0.25
chr6_35279100_35279566 0.35 DEF6
differentially expressed in FDCP 6 homolog (mouse)
1818
0.34
chr20_33102938_33103232 0.35 DYNLRB1
dynein, light chain, roadblock-type 1
1129
0.43
chr2_205920685_205921182 0.35 PARD3B
par-3 family cell polarity regulator beta
510210
0.0
chr4_77226594_77226879 0.35 FAM47E-STBD1
FAM47E-STBD1 readthrough
443
0.83
chr1_29254208_29254684 0.35 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
13355
0.18
chr9_95055581_95055984 0.34 IARS
isoleucyl-tRNA synthetase
141
0.91
chr2_198379866_198380021 0.34 MOB4
MOB family member 4, phocein
352
0.79

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of OSR1_OSR2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.2 0.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.5 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.7 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.6 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.8 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.3 GO:0001821 histamine secretion(GO:0001821)
0.1 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.1 GO:0019042 viral latency(GO:0019042)
0.1 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.3 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.2 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.3 GO:0014805 smooth muscle adaptation(GO:0014805)
0.1 0.2 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.2 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.1 0.6 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.3 GO:2000319 T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1 0.2 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.3 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.4 GO:0043368 positive T cell selection(GO:0043368)
0.1 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.3 GO:0070670 response to interleukin-4(GO:0070670)
0.1 0.5 GO:0007141 male meiosis I(GO:0007141)
0.1 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0010224 response to UV-B(GO:0010224)
0.0 0.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.0 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.2 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.1 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0048548 regulation of pinocytosis(GO:0048548)
0.0 0.0 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) negative regulation of lipoprotein particle clearance(GO:0010985)
0.0 0.1 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.2 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0006534 cysteine metabolic process(GO:0006534)
0.0 0.1 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.2 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 1.0 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.4 GO:0032727 positive regulation of interferon-alpha production(GO:0032727)
0.0 0.2 GO:0006273 lagging strand elongation(GO:0006273)
0.0 0.0 GO:0070391 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0 0.1 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.3 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.2 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.4 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.1 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0016556 mRNA modification(GO:0016556)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.1 GO:0071027 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.2 GO:0000018 regulation of DNA recombination(GO:0000018)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.4 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:1904063 negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.6 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.0 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.6 GO:0046464 neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0090114 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.2 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.1 GO:0046634 regulation of alpha-beta T cell activation(GO:0046634)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.5 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.0 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.1 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0002467 germinal center formation(GO:0002467)
0.0 0.2 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.0 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.3 GO:0075733 multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.2 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.1 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.0 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.5 GO:0001906 cell killing(GO:0001906)
0.0 0.0 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.0 GO:0001743 optic placode formation(GO:0001743)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.4 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.1 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.9 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.4 GO:0016064 immunoglobulin mediated immune response(GO:0016064) B cell mediated immunity(GO:0019724)
0.0 0.2 GO:0016045 detection of bacterium(GO:0016045)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.0 GO:0060058 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.2 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.0 GO:0051136 NK T cell differentiation(GO:0001865) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.5 GO:0007632 visual behavior(GO:0007632)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.4 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.0 GO:0051709 regulation of killing of cells of other organism(GO:0051709) positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:1904376 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0032239 regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.0 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.2 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 1.3 GO:0006959 humoral immune response(GO:0006959)
0.0 0.1 GO:0030147 obsolete natriuresis(GO:0030147)
0.0 0.1 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.0 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.0 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.0 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0042508 tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.0 0.0 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.0 GO:0002820 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.0 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579) positive regulation of dendritic cell antigen processing and presentation(GO:0002606) interleukin-3 production(GO:0032632)
0.0 0.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.0 GO:0010225 response to UV-C(GO:0010225)
0.0 0.0 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.8 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0042770 signal transduction in response to DNA damage(GO:0042770)
0.0 0.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:0000216 obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0 0.0 GO:0032604 granulocyte macrophage colony-stimulating factor production(GO:0032604) regulation of granulocyte macrophage colony-stimulating factor production(GO:0032645)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.9 GO:0044783 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
0.0 2.0 GO:0050776 regulation of immune response(GO:0050776)
0.0 0.0 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.6 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.0 GO:2000757 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.0 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320) pro-B cell differentiation(GO:0002328)
0.0 0.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.0 GO:0060760 positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.0 GO:0044252 negative regulation of collagen metabolic process(GO:0010713) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.1 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.0 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.0 GO:0032479 regulation of type I interferon production(GO:0032479)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:1901998 antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.3 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.0 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.4 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.0 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.0 GO:0090559 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.6 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082) cell cycle G1/S phase transition(GO:0044843)
0.0 0.0 GO:0045006 DNA deamination(GO:0045006)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.1 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.0 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.0 GO:0031057 negative regulation of histone modification(GO:0031057)
0.0 0.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.0 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0000050 urea cycle(GO:0000050)
0.0 0.0 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.0 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.0 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.0 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.0 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.4 GO:0016571 histone methylation(GO:0016571)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.7 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0097191 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.1 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.0 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.1 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.3 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.0 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.0 GO:0032735 positive regulation of interleukin-12 production(GO:0032735)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0000154 rRNA modification(GO:0000154)
0.0 0.0 GO:1902743 regulation of lamellipodium organization(GO:1902743)
0.0 0.2 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.0 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.0 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.0 GO:0045060 negative thymic T cell selection(GO:0045060)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0072487 MSL complex(GO:0072487)
0.1 0.6 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.5 GO:0070688 MLL5-L complex(GO:0070688)
0.1 0.3 GO:0071778 obsolete WINAC complex(GO:0071778)
0.1 0.2 GO:0005827 polar microtubule(GO:0005827)
0.1 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.0 GO:0033391 chromatoid body(GO:0033391)
0.0 1.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 1.2 GO:0034708 methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.8 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.9 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.7 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.0 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.0 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 2.6 GO:0016604 nuclear body(GO:0016604)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.0 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 1.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.3 GO:0019863 IgE binding(GO:0019863)
0.1 0.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.4 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 1.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.5 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0046979 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.0 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.0 GO:0005035 death receptor activity(GO:0005035)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.0 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0035586 G-protein coupled adenosine receptor activity(GO:0001609) purinergic receptor activity(GO:0035586)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.6 GO:0019210 kinase inhibitor activity(GO:0019210)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.0 GO:0033265 choline binding(GO:0033265)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.0 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.5 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.0 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.0 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.0 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.0 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0042393 histone binding(GO:0042393)
0.0 0.4 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0050664 superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.8 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 0.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 3.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.2 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 0.3 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 0.2 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.1 3.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.8 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.0 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.1 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.0 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0 0.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.8 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.1 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.0 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex