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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for OTX1

Z-value: 1.41

Motif logo

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Transcription factors associated with OTX1

Gene Symbol Gene ID Gene Info
OTX1
ENSG00000115507.5 orthodenticle homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr2_63276750_63277690OTX1280.9722230.722.8e-02Click!
chr2_63278835_63278986OTX19730.5937220.617.9e-02Click!
chr2_63279236_63279503OTX114320.4583190.541.3e-01Click!
chr2_63278511_63278672OTX16540.7345230.511.6e-01Click!
chr2_63287244_63287598OTX194840.232922-0.472.0e-01Click!

Activity of the OTX1 motif across conditions

Conditions sorted by the z-value of the OTX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_122050649_122050906 0.60 ENSG00000207994
 .
 27761
 0.16
chr1_162532316_162532688 0.50 UAP1
 UDP-N-acteylglucosamine pyrophosphorylase 1
 1179
 0.36
chr8_94930403_94930714 0.49 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
 580
 0.72
chr3_98619475_98619750 0.48 DCBLD2
 discoidin, CUB and LCCL domain containing 2
 403
 0.8
chr2_151334124_151334616 0.48 RND3
 Rho family GTPase 3
 7526
 0.34
chr4_90581488_90581639 0.46 RP11-115D19.1
21100
 0.27
chr11_79150433_79150655 0.46 TENM4
 teneurin transmembrane protein 4
 1151
 0.54
chr5_98111445_98111873 0.45 RGMB
 repulsive guidance molecule family member b
 2320
 0.3
chr5_171708618_171708769 0.43 UBTD2
 ubiquitin domain containing 2
 2382
 0.24
chr15_45570927_45571126 0.42 CTD-2651B20.3
399
 0.8
chr22_44722319_44722530 0.41 KIAA1644
 KIAA1644
 13693
 0.24
chr1_119529068_119529220 0.41 TBX15
 T-box 15
 1284
 0.57
chr5_78712583_78712734 0.40 HOMER1
 homer homolog 1 (Drosophila)
 95959
 0.08
chr3_30659362_30659513 0.39 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 11344
 0.29
chr6_84761983_84762373 0.38 MRAP2
 melanocortin 2 receptor accessory protein 2
 18703
 0.28
chr19_47756874_47757099 0.37 CCDC9
 coiled-coil domain containing 9
 2730
 0.19
chr2_9815352_9815503 0.37 YWHAQ
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
 44284
 0.14
chr2_9376393_9376544 0.35 ASAP2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
 29574
 0.23
chr5_72715364_72715530 0.34 FOXD1
 forkhead box D1
 28905
 0.18
chr3_197022890_197023199 0.34 DLG1
 discs, large homolog 1 (Drosophila)
 1031
 0.42
chr10_114714022_114714173 0.34 RP11-57H14.2
2463
 0.3
chr15_36693921_36694243 0.34 C15orf41
 chromosome 15 open reading frame 41
 177730
 0.03
chr1_23449014_23449165 0.33 LUZP1
 leucine zipper protein 1
 11083
 0.14
chr7_156791129_156791280 0.33 MNX1-AS2
 MNX1 antisense RNA 2
 7797
 0.17
chr8_117698220_117698371 0.33 EIF3H
 eukaryotic translation initiation factor 3, subunit H
 69728
 0.11
chr1_171614800_171614951 0.33 MYOC
 myocilin, trabecular meshwork inducible glucocorticoid response
 6948
 0.24
chr3_25513057_25513453 0.33 RARB
 retinoic acid receptor, beta
 13454
 0.26
chr11_16946573_16946796 0.33 PLEKHA7
 pleckstrin homology domain containing, family A member 7
 43779
 0.12
chr10_114552786_114553214 0.33 RP11-57H14.4
30249
 0.21
chr3_156561167_156561375 0.32 LEKR1
 leucine, glutamate and lysine rich 1
 17123
 0.27
chr10_95518290_95518441 0.32 LGI1
 leucine-rich, glioma inactivated 1
 687
 0.76
chr14_53773167_53773351 0.32 RP11-547D23.1
153187
 0.04
chr5_177631147_177631350 0.32 HNRNPAB
 heterogeneous nuclear ribonucleoprotein A/B
 260
 0.92
chr2_237477915_237478284 0.32 ACKR3
 atypical chemokine receptor 3
 185
 0.97
chr4_124267046_124267197 0.31 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 50829
 0.19
chr1_193154702_193155811 0.31 B3GALT2
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
 528
 0.8
chr14_68466898_68467139 0.31 CTD-2566J3.1
129895
 0.05
chr6_147236233_147236440 0.31 STXBP5-AS1
 STXBP5 antisense RNA 1
 685
 0.82
chr4_177711668_177712016 0.31 VEGFC
 vascular endothelial growth factor C
 2039
 0.48
chr8_129873562_129874058 0.30 ENSG00000221351
 .
 41770
 0.22
chr2_163157606_163157781 0.30 IFIH1
 interferon induced with helicase C domain 1
 17501
 0.19
chr8_101859554_101859783 0.30 ENSG00000222795
 .
 15580
 0.19
chr7_94273794_94273945 0.30 SGCE
 sarcoglycan, epsilon
 11541
 0.21
chr2_204398750_204399136 0.30 RAPH1
 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
 787
 0.76
chr5_72146808_72146959 0.29 TNPO1
 transportin 1
 2872
 0.27
chr20_34471632_34471916 0.29 ENSG00000201221
 .
 3807
 0.18
chr12_31522871_31523058 0.29 ENSG00000207477
 .
 3742
 0.2
chr3_149374923_149375174 0.29 WWTR1
 WW domain containing transcription regulator 1
 174
 0.54
chr7_42275396_42275690 0.29 GLI3
 GLI family zinc finger 3
 1069
 0.7
chr22_36232996_36233711 0.29 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 2912
 0.37
chr15_31276777_31276928 0.29 MTMR10
 myotubularin related protein 10
 6766
 0.17
chr5_145207148_145207299 0.28 PRELID2
 PRELI domain containing 2
 7625
 0.27
chrX_139584639_139584790 0.28 SOX3
 SRY (sex determining region Y)-box 3
 2511
 0.41
chr13_107182142_107182293 0.28 EFNB2
 ephrin-B2
 5245
 0.29
chr9_2655572_2655791 0.28 RP11-125B21.2
14286
 0.23
chr1_12675825_12676469 0.28 DHRS3
 dehydrogenase/reductase (SDR family) member 3
 1590
 0.37
chr4_86417012_86417203 0.28 ARHGAP24
 Rho GTPase activating protein 24
 20716
 0.29
chr6_106546757_106547354 0.28 PRDM1
 PR domain containing 1, with ZNF domain
 240
 0.87
chr12_4967146_4967345 0.27 RP3-377H17.2
19124
 0.2
chr6_132180195_132180361 0.27 ENSG00000200895
 .
 38804
 0.14
chr3_40428700_40429091 0.27 ENTPD3
 ectonucleoside triphosphate diphosphohydrolase 3
 159
 0.96
chr1_213500454_213500722 0.26 RPS6KC1
 ribosomal protein S6 kinase, 52kDa, polypeptide 1
 275984
 0.01
chr7_103969727_103969878 0.26 LHFPL3
 lipoma HMGIC fusion partner-like 3
 654
 0.83
chr14_85998679_85999082 0.26 FLRT2
 fibronectin leucine rich transmembrane protein 2
 2308
 0.36
chr3_4624343_4624494 0.26 ITPR1
 inositol 1,4,5-trisphosphate receptor, type 1
 66242
 0.12
chr6_27722042_27722205 0.26 HIST1H2BL
 histone cluster 1, H2bl
 53586
 0.06
chr5_80256040_80256245 0.26 RASGRF2
 Ras protein-specific guanine nucleotide-releasing factor 2
 349
 0.67
chr11_131780111_131780399 0.26 NTM
 neurotrimin
 642
 0.77
chr11_125497097_125497248 0.26 CHEK1
 checkpoint kinase 1
 529
 0.7
chr1_1927919_1928070 0.26 C1orf222
 chromosome 1 open reading frame 222
 5626
 0.14
chr3_29325145_29325351 0.26 RBMS3
 RNA binding motif, single stranded interacting protein 3
 2141
 0.37
chr7_42420275_42420426 0.26 GLI3
 GLI family zinc finger 3
 143692
 0.05
chr17_14028855_14029146 0.25 ENSG00000252305
 .
 51448
 0.12
chr8_62496427_62496578 0.25 ENSG00000222898
 .
 48069
 0.16
chr18_61555988_61556228 0.25 SERPINB2
 serpin peptidase inhibitor, clade B (ovalbumin), member 2
 1115
 0.49
chr6_170597728_170597879 0.25 DLL1
 delta-like 1 (Drosophila)
 1758
 0.29
chr14_55119300_55119828 0.25 SAMD4A
 sterile alpha motif domain containing 4A
 84927
 0.09
chr10_93684687_93684838 0.25 BTAF1
 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
 1236
 0.47
chr5_148926669_148926913 0.25 CSNK1A1
 casein kinase 1, alpha 1
 3071
 0.22
chr18_35145104_35145551 0.25 CELF4
 CUGBP, Elav-like family member 4
 277
 0.95
chr1_86048991_86049142 0.25 CYR61
 cysteine-rich, angiogenic inducer, 61
 2622
 0.26
chr7_123389891_123390042 0.25 RP11-390E23.6
844
 0.4
chr8_38899834_38899985 0.25 ENSG00000207199
 .
 23707
 0.15
chr10_70096270_70096993 0.25 PBLD
 phenazine biosynthesis-like protein domain containing
 3825
 0.2
chr3_135741763_135741914 0.25 PPP2R3A
 protein phosphatase 2, regulatory subunit B'', alpha
 261
 0.95
chr16_57849974_57850125 0.25 CTD-2600O9.1
 uncharacterized protein LOC388282
 2365
 0.22
chr18_21851017_21851223 0.25 OSBPL1A
 oxysterol binding protein-like 1A
 1076
 0.43
chr19_47776409_47776560 0.25 PRR24
 proline rich 24
 1658
 0.28
chr13_25745649_25746102 0.24 AMER2
 APC membrane recruitment protein 2
 18
 0.98
chr13_114567217_114567395 0.24 GAS6
 growth arrest-specific 6
 260
 0.94
chr3_111673457_111673608 0.24 ABHD10
 abhydrolase domain containing 10
 24325
 0.17
chr17_46664636_46664902 0.24 HOXB3
 homeobox B3
 2828
 0.09
chr2_27487055_27487432 0.24 SLC30A3
 solute carrier family 30 (zinc transporter), member 3
 239
 0.85
chr8_31134922_31135073 0.24 RP11-363L24.3
100314
 0.08
chr9_73979405_73979556 0.24 TRPM3
 transient receptor potential cation channel, subfamily M, member 3
 82271
 0.11
chr1_224545541_224545743 0.24 CNIH4
 cornichon family AMPA receptor auxiliary protein 4
 1047
 0.45
chr2_120518344_120518699 0.24 PTPN4
 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
 721
 0.76
chr2_129315776_129315927 0.24 ENSG00000238379
 .
 113079
 0.07
chr8_49830829_49831037 0.24 SNAI2
 snail family zinc finger 2
 3055
 0.4
chr2_216948558_216948709 0.24 TMEM169
 transmembrane protein 169
 1991
 0.27
chr19_2984028_2984281 0.23 TLE6
 transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
 6576
 0.14
chr17_43971204_43971355 0.23 MAPT
 microtubule-associated protein tau
 469
 0.73
chr2_102720712_102721707 0.23 IL1R1
 interleukin 1 receptor, type I
 180
 0.96
chr9_21558481_21558945 0.23 MIR31HG
 MIR31 host gene (non-protein coding)
 955
 0.56
chr8_67977563_67977802 0.23 COPS5
 COP9 signalosome subunit 5
 504
 0.63
chr4_33952877_33953028 0.23 ENSG00000251755
 .
 166395
 0.04
chr5_73926204_73926355 0.23 HEXB
 hexosaminidase B (beta polypeptide)
 9569
 0.21
chr1_201605392_201605543 0.23 NAV1
 neuron navigator 1
 11910
 0.15
chr3_128892906_128893057 0.23 CNBP
 CCHC-type zinc finger, nucleic acid binding protein
 9761
 0.13
chr8_135790318_135790469 0.23 ENSG00000207582
 .
 22457
 0.21
chr13_44842345_44842496 0.23 SERP2
 stress-associated endoplasmic reticulum protein family member 2
 105558
 0.06
chr6_156349604_156349763 0.23 ENSG00000221456
 .
 81752
 0.12
chr7_121944988_121945139 0.23 FEZF1-AS1
 FEZF1 antisense RNA 1
 59
 0.89
chr7_83946098_83946249 0.23 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
 121412
 0.07
chr15_38545953_38546360 0.23 SPRED1
 sprouty-related, EVH1 domain containing 1
 774
 0.79
chr3_185651354_185651505 0.23 TRA2B
 transformer 2 beta homolog (Drosophila)
 4372
 0.23
chr2_208027525_208027676 0.23 KLF7
 Kruppel-like factor 7 (ubiquitous)
 2695
 0.3
chr10_33620140_33620362 0.23 NRP1
 neuropilin 1
 3059
 0.34
chr3_192958571_192958786 0.22 HRASLS
 HRAS-like suppressor
 236
 0.96
chr5_171115385_171115536 0.22 ENSG00000264303
 .
 82074
 0.09
chr13_110320110_110320261 0.22 LINC00676
 long intergenic non-protein coding RNA 676
 60444
 0.15
chr5_125760300_125760451 0.22 GRAMD3
 GRAM domain containing 3
 1225
 0.57
chr16_86888410_86888561 0.22 FOXL1
 forkhead box L1
 276370
 0.01
chr9_73483972_73484180 0.22 TRPM3
 transient receptor potential cation channel, subfamily M, member 3
 102
 0.98
chr2_102327994_102328145 0.22 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
 13077
 0.29
chr17_56013006_56013279 0.22 CUEDC1
 CUE domain containing 1
 19476
 0.15
chr19_46965021_46965172 0.22 PNMAL1
 paraneoplastic Ma antigen family-like 1
 9568
 0.14
chr11_2404011_2404162 0.22 CD81
 CD81 molecule
 396
 0.75
chr6_148593838_148594147 0.22 SASH1
 SAM and SH3 domain containing 1
 552
 0.78
chr14_55077622_55077773 0.22 SAMD4A
 sterile alpha motif domain containing 4A
 43060
 0.17
chr4_160173723_160173874 0.22 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
 14235
 0.23
chr9_95298468_95298698 0.22 ECM2
 extracellular matrix protein 2, female organ and adipocyte specific
 246
 0.92
chr9_21558983_21559308 0.22 MIR31HG
 MIR31 host gene (non-protein coding)
 523
 0.78
chr2_219828438_219828589 0.22 AC097468.7
1888
 0.18
chr7_28682052_28682203 0.22 CREB5
 cAMP responsive element binding protein 5
 33449
 0.24
chr3_8808825_8808976 0.22 OXTR
 oxytocin receptor
 1463
 0.34
chr14_77490003_77490186 0.22 IRF2BPL
 interferon regulatory factor 2 binding protein-like
 4940
 0.22
chr8_67343981_67344272 0.22 ADHFE1
 alcohol dehydrogenase, iron containing, 1
 592
 0.73
chrX_17431758_17432043 0.22 ENSG00000265465
 .
 12104
 0.22
chr6_28806796_28807125 0.22 ENSG00000265764
 .
 43148
 0.11
chr3_173302379_173302636 0.22 NLGN1
 neuroligin 1
 162
 0.98
chr12_113375085_113375236 0.22 OAS3
 2'-5'-oligoadenylate synthetase 3, 100kDa
 997
 0.54
chr13_30276703_30277107 0.22 SLC7A1
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
 107080
 0.07
chr2_159251872_159252065 0.22 CCDC148
 coiled-coil domain containing 148
 14496
 0.23
chr6_11230027_11230357 0.22 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 2699
 0.33
chr10_14051003_14051266 0.22 FRMD4A
 FERM domain containing 4A
 602
 0.78
chr10_33620428_33620906 0.21 NRP1
 neuropilin 1
 2643
 0.37
chr3_58983787_58983938 0.21 C3orf67
 chromosome 3 open reading frame 67
 51855
 0.18
chr8_93069724_93069875 0.21 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 5392
 0.33
chr13_35517642_35517793 0.21 NBEA
 neurobeachin
 920
 0.75
chr10_63809082_63810748 0.21 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 945
 0.69
chr6_27636067_27636272 0.21 ENSG00000238648
 .
 36981
 0.14
chr2_206610963_206611114 0.21 AC007362.3
17639
 0.25
chr11_108724912_108725630 0.21 ENSG00000201243
 .
 150973
 0.04
chr7_18550520_18550717 0.21 HDAC9
 histone deacetylase 9
 1682
 0.51
chr9_24326132_24326283 0.21 IZUMO3
 IZUMO family member 3
 219467
 0.02
chr12_90272914_90273065 0.21 ENSG00000252823
 .
 125153
 0.06
chr2_113916305_113916585 0.21 PSD4
 pleckstrin and Sec7 domain containing 4
 15103
 0.13
chr1_6269211_6269420 0.21 RPL22
 ribosomal protein L22
 11
 0.96
chr1_68414425_68414576 0.21 GNG12-AS1
 GNG12 antisense RNA 1
 6588
 0.28
chr13_107185720_107185941 0.21 EFNB2
 ephrin-B2
 1632
 0.49
chr19_48614158_48614373 0.21 PLA2G4C
 phospholipase A2, group IVC (cytosolic, calcium-independent)
 191
 0.91
chr5_114713190_114713401 0.21 CCDC112
 coiled-coil domain containing 112
 80767
 0.09
chr7_130596201_130596683 0.21 ENSG00000226380
 .
 34144
 0.19
chr17_27135559_27135731 0.21 FAM222B
 family with sequence similarity 222, member B
 3597
 0.1
chr16_22038297_22038549 0.21 C16orf52
 chromosome 16 open reading frame 52
 18819
 0.15
chr2_71205181_71205355 0.21 ANKRD53
 ankyrin repeat domain 53
 242
 0.83
chr6_134211072_134211606 0.21 TCF21
 transcription factor 21
 866
 0.5
chr2_201248196_201249000 0.20 ENSG00000264798
 .
 3300
 0.23
chr3_61913363_61913514 0.20 ENSG00000252420
 .
 188535
 0.03
chr4_85503338_85503489 0.20 CDS1
 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
 719
 0.78
chr20_48565386_48565537 0.20 ENSG00000239157
 .
 8524
 0.13
chr9_18475768_18475931 0.20 ADAMTSL1
 ADAMTS-like 1
 1618
 0.53
chrX_33573585_33573736 0.20 DMD
 dystrophin
 216102
 0.02
chr3_54674397_54674548 0.20 ESRG
 embryonic stem cell related (non-protein coding)
 588
 0.86
chr19_32828053_32828204 0.20 ZNF507
 zinc finger protein 507
 8372
 0.19
chr1_214279767_214279918 0.20 RP11-53A1.2
75733
 0.11
chr2_176997573_176997736 0.20 HOXD8
 homeobox D8
 2569
 0.11
chr1_79115791_79116542 0.20 IFI44
 interferon-induced protein 44
 649
 0.75
chr10_10834897_10835048 0.20 CELF2
 CUGBP, Elav-like family member 2
 212287
 0.02
chr6_3844247_3844398 0.20 FAM50B
 family with sequence similarity 50, member B
 5298
 0.22
chr12_13079095_13079275 0.20 RP11-392P7.6
1475
 0.3
chr10_65282301_65282503 0.20 REEP3
 receptor accessory protein 3
 1279
 0.55
chr6_142360108_142360259 0.20 RP11-137J7.2
49187
 0.15
chr7_132260236_132260613 0.20 PLXNA4
 plexin A4
 805
 0.75
chr8_42748827_42749465 0.20 ENSG00000266044
 .
 2272
 0.19
chr19_51308481_51308642 0.20 C19orf48
 chromosome 19 open reading frame 48
 375
 0.65
chr6_116693696_116693937 0.20 DSE
 dermatan sulfate epimerase
 1706
 0.38
chr12_76740590_76740888 0.20 BBS10
 Bardet-Biedl syndrome 10
 1483
 0.48
chr14_65801219_65801685 0.20 ENSG00000266740
 .
 449
 0.88
chr21_18348624_18348775 0.20 ENSG00000239023
 .
 257382
 0.02
chr3_104156196_104156347 0.20 ENSG00000265076
 .
 382631
 0.01
chr6_106547367_106547905 0.20 RP1-134E15.3
379
 0.74
chrY_2620247_2620578 0.20 ENSG00000251841
 .
 32378
 0.19
chr16_4368544_4368842 0.20 GLIS2
 GLIS family zinc finger 2
 3931
 0.16
chr2_70140665_70140816 0.20 ENSG00000238465
 .
 913
 0.4
chr8_69879858_69880009 0.20 ENSG00000238808
 .
 142876
 0.05
chr1_97850069_97850220 0.19 DPYD-IT1
 DPYD intronic transcript 1 (non-protein coding)
 35553
 0.24
chr6_19803841_19803992 0.19 ID4
 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
 33701
 0.2
chr22_31692523_31692674 0.19 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
 4078
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.3 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.2 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 0.2 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.4 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.5 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0001553 luteinization(GO:0001553)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.2 GO:0045217 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.2 GO:0000959 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.0 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0021955 central nervous system projection neuron axonogenesis(GO:0021952) central nervous system neuron axonogenesis(GO:0021955)
0.0 0.1 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.1 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.0 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.0 0.0 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0090399 replicative senescence(GO:0090399)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.2 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0034227 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.2 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.3 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.0 GO:0010523 negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0 0.0 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.0 GO:0051307 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.2 GO:0001706 endoderm formation(GO:0001706)
0.0 0.0 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.0 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0071027 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.0 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.0 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 0.0 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0021554 optic nerve development(GO:0021554)
0.0 0.0 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.0 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0090114 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.1 GO:0060045 positive regulation of cardiac muscle tissue growth(GO:0055023) positive regulation of cardiac muscle tissue development(GO:0055025) positive regulation of cardiac muscle cell proliferation(GO:0060045)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.2 GO:0035088 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0 0.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.0 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.0 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0008347 glial cell migration(GO:0008347)
0.0 0.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0051593 response to folic acid(GO:0051593)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.0 GO:0072191 positive regulation of smooth muscle cell differentiation(GO:0051152) ureter development(GO:0072189) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193) kidney smooth muscle tissue development(GO:0072194)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0071800 podosome assembly(GO:0071800)
0.0 0.2 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.4 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.0 0.2 GO:0008038 neuron recognition(GO:0008038)
0.0 0.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0048194 vesicle coating(GO:0006901) COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) single-organism membrane budding(GO:1902591)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.0 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.0 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045298 tubulin complex(GO:0045298)
0.1 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.0 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.5 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.1 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.0 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.0 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines