Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
Navigation
Downloads
Logo

Results for OTX2_CRX

Z-value: 0.60

Motif logo

logo of logo of

Transcription factors associated with OTX2_CRX

Gene Symbol Gene ID Gene Info
OTX2
ENSG00000165588.12 orthodenticle homeobox 2
CRX
ENSG00000105392.11 cone-rod homeobox

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr14_57274863_57275150OTX221600.2603730.646.3e-02Click!
chr14_57275358_57275543OTX217160.3094140.452.2e-01Click!
chr14_57264424_57264575OTX278670.170193-0.363.4e-01Click!
chr14_57274118_57274269OTX218120.3003790.284.6e-01Click!
chr14_57274481_57274632OTX221750.2604770.235.4e-01Click!

Activity of the OTX2_CRX motif across conditions

Conditions sorted by the z-value of the OTX2_CRX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr15_89914451_89914936 0.11 ENSG00000207819
 .
 3445
 0.23
chrX_34671991_34672311 0.10 TMEM47
 transmembrane protein 47
 3254
 0.41
chr2_36585229_36585663 0.10 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 1832
 0.5
chr8_58907686_58908288 0.10 FAM110B
 family with sequence similarity 110, member B
 874
 0.76
chr3_49169788_49170138 0.10 LAMB2
 laminin, beta 2 (laminin S)
 490
 0.65
chr9_90588787_90589959 0.09 CDK20
 cyclin-dependent kinase 20
 29
 0.98
chr5_3598562_3598819 0.09 CTD-2012M11.3
1612
 0.42
chr3_123518515_123518699 0.09 MYLK
 myosin light chain kinase
 5919
 0.23
chr4_112600114_112600265 0.08 ENSG00000200963
 .
 347621
 0.01
chr2_12842465_12842741 0.08 TRIB2
 tribbles pseudokinase 2
 14412
 0.26
chrX_99899847_99900028 0.08 SRPX2
 sushi-repeat containing protein, X-linked 2
 722
 0.65
chr14_27065271_27065422 0.08 NOVA1
 neuro-oncological ventral antigen 1
 65
 0.96
chr11_130320694_130320845 0.08 ADAMTS15
 ADAM metallopeptidase with thrombospondin type 1 motif, 15
 1900
 0.41
chr4_75718841_75720131 0.08 BTC
 betacellulin
 410
 0.91
chr13_65834890_65835427 0.08 ENSG00000221685
 .
 603147
 0.0
chr14_53301814_53302501 0.08 FERMT2
 fermitin family member 2
 29082
 0.15
chr6_26575872_26576023 0.08 ABT1
 activator of basal transcription 1
 21233
 0.14
chr19_6740138_6741070 0.07 TRIP10
 thyroid hormone receptor interactor 10
 325
 0.81
chr1_114522384_114522566 0.07 OLFML3
 olfactomedin-like 3
 220
 0.93
chr16_75232194_75232506 0.07 CTRB2
 chymotrypsinogen B2
 7343
 0.14
chr16_54969072_54969449 0.07 IRX5
 iroquois homeobox 5
 3276
 0.4
chr3_155109533_155109828 0.07 ENSG00000272096
 .
 45932
 0.16
chr7_73867713_73868217 0.07 GTF2IRD1
 GTF2I repeat domain containing 1
 155
 0.96
chr2_170366040_170366191 0.07 KLHL41
 kelch-like family member 41
 97
 0.97
chr6_46458168_46458592 0.07 RCAN2
 regulator of calcineurin 2
 719
 0.62
chr3_87040086_87040946 0.07 VGLL3
 vestigial like 3 (Drosophila)
 247
 0.96
chr13_34250323_34250584 0.07 RFC3
 replication factor C (activator 1) 3, 38kDa
 141733
 0.05
chr16_28549300_28549715 0.07 NUPR1
 nuclear protein, transcriptional regulator, 1
 822
 0.5
chr8_136478593_136478847 0.07 KHDRBS3
 KH domain containing, RNA binding, signal transduction associated 3
 7770
 0.25
chr22_31198410_31198813 0.07 OSBP2
 oxysterol binding protein 2
 462
 0.84
chr20_49307514_49308405 0.07 FAM65C
 family with sequence similarity 65, member C
 43
 0.97
chr1_235795999_235796340 0.07 GNG4
 guanine nucleotide binding protein (G protein), gamma 4
 17124
 0.25
chr5_9546839_9547056 0.07 SEMA5A
 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
 760
 0.6
chr7_93552303_93552503 0.07 GNG11
 guanine nucleotide binding protein (G protein), gamma 11
 1392
 0.38
chr16_54970178_54971110 0.07 IRX5
 iroquois homeobox 5
 4660
 0.36
chr15_38547303_38547454 0.07 SPRED1
 sprouty-related, EVH1 domain containing 1
 1996
 0.49
chr19_10444919_10445184 0.07 ICAM3
 intercellular adhesion molecule 3
 348
 0.62
chr8_55294582_55295235 0.07 ENSG00000244107
 .
 38120
 0.17
chr9_89049166_89049463 0.07 ENSG00000222293
 .
 11271
 0.28
chr1_215257188_215257339 0.07 KCNK2
 potassium channel, subfamily K, member 2
 403
 0.92
chr12_81102183_81102935 0.07 MYF6
 myogenic factor 6 (herculin)
 1282
 0.49
chr10_97049818_97050125 0.07 PDLIM1
 PDZ and LIM domain 1
 810
 0.7
chr6_35286420_35286751 0.07 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 9070
 0.18
chr18_20746992_20747143 0.07 CABLES1
 Cdk5 and Abl enzyme substrate 1
 11278
 0.21
chr12_3308931_3310293 0.07 TSPAN9
 tetraspanin 9
 729
 0.75
chr18_53530407_53530634 0.07 TCF4
 transcription factor 4
 198502
 0.03
chr10_95848621_95848951 0.07 PLCE1
 phospholipase C, epsilon 1
 44
 0.97
chr3_28383486_28383637 0.07 AZI2
 5-azacytidine induced 2
 6407
 0.24
chr10_77159524_77159700 0.06 ENSG00000237149
 .
 1665
 0.33
chr12_1427708_1428104 0.06 RP5-951N9.2
67093
 0.11
chr1_164531408_164531670 0.06 PBX1
 pre-B-cell leukemia homeobox 1
 503
 0.87
chr1_8772244_8772432 0.06 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 9060
 0.25
chr1_91191218_91191722 0.06 BARHL2
 BarH-like homeobox 2
 8676
 0.3
chr10_119303944_119304573 0.06 EMX2OS
 EMX2 opposite strand/antisense RNA
 321
 0.88
chr3_112359594_112359745 0.06 CCDC80
 coiled-coil domain containing 80
 447
 0.87
chr14_35179773_35180008 0.06 CFL2
 cofilin 2 (muscle)
 3144
 0.26
chr2_176987899_176988234 0.06 HOXD9
 homeobox D9
 978
 0.29
chr4_164253766_164254020 0.06 NPY1R
 neuropeptide Y receptor Y1
 121
 0.97
chr12_91576386_91576586 0.06 DCN
 decorin
 0
 0.99
chr2_164591967_164592245 0.06 FIGN
 fidgetin
 411
 0.92
chr17_762649_762818 0.06 NXN
 nucleoredoxin
 4604
 0.18
chr1_39735914_39736147 0.06 MACF1
 microtubule-actin crosslinking factor 1
 1831
 0.35
chr18_12309515_12309681 0.06 TUBB6
 tubulin, beta 6 class V
 1336
 0.41
chr15_65901005_65901156 0.06 VWA9
 von Willebrand factor A domain containing 9
 2327
 0.2
chr2_216299709_216300678 0.06 FN1
 fibronectin 1
 597
 0.55
chr13_30276703_30277107 0.06 SLC7A1
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
 107080
 0.07
chr8_99963595_99963771 0.06 OSR2
 odd-skipped related transciption factor 2
 3063
 0.23
chr9_73483972_73484180 0.06 TRPM3
 transient receptor potential cation channel, subfamily M, member 3
 102
 0.98
chr20_19974216_19974491 0.06 NAA20
 N(alpha)-acetyltransferase 20, NatB catalytic subunit
 23407
 0.19
chr15_32933967_32934156 0.06 SCG5
 secretogranin V (7B2 protein)
 158
 0.94
chr2_216298025_216298259 0.06 FN1
 fibronectin 1
 2648
 0.29
chr1_92907603_92907960 0.06 ENSG00000242764
 .
 39539
 0.16
chr13_114792883_114793184 0.06 RASA3
 RAS p21 protein activator 3
 50405
 0.16
chr2_207307729_207308161 0.06 ADAM23
 ADAM metallopeptidase domain 23
 318
 0.92
chr6_113953461_113953992 0.06 ENSG00000266650
 .
 29609
 0.21
chr13_36704166_36704317 0.06 DCLK1
 doublecortin-like kinase 1
 1202
 0.59
chrX_3263508_3263724 0.06 MXRA5
 matrix-remodelling associated 5
 1066
 0.64
chr7_55089371_55089524 0.06 EGFR
 epidermal growth factor receptor
 2636
 0.41
chr6_128977127_128977410 0.06 ENSG00000238938
 .
 42922
 0.16
chr16_55090478_55090815 0.06 IRX5
 iroquois homeobox 5
 124662
 0.06
chr19_46286294_46286481 0.06 DMPK
 dystrophia myotonica-protein kinase
 640
 0.45
chr22_38657243_38657394 0.06 TMEM184B
 transmembrane protein 184B
 11352
 0.11
chr15_95217234_95217771 0.06 MCTP2
 multiple C2 domains, transmembrane 2
 318299
 0.01
chr1_75138923_75139762 0.06 C1orf173
 chromosome 1 open reading frame 173
 80
 0.98
chr5_9544908_9545592 0.06 SEMA5A
 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
 937
 0.56
chr5_95950045_95950381 0.06 ENSG00000238518
 .
 24233
 0.16
chr11_125497097_125497248 0.06 CHEK1
 checkpoint kinase 1
 529
 0.7
chr3_170132220_170132371 0.06 CLDN11
 claudin 11
 4358
 0.29
chr4_115520348_115520872 0.06 UGT8
 UDP glycosyltransferase 8
 684
 0.8
chr3_112961154_112961680 0.06 BOC
 BOC cell adhesion associated, oncogene regulated
 26219
 0.19
chr3_123168721_123169253 0.06 ADCY5
 adenylate cyclase 5
 382
 0.9
chr4_150453103_150453254 0.06 ENSG00000202331
 .
 375534
 0.01
chr12_50636266_50636502 0.06 LIMA1
 LIM domain and actin binding 1
 7292
 0.13
chr15_35949903_35950054 0.06 DPH6
 diphthamine biosynthesis 6
 111585
 0.07
chr16_53086342_53086851 0.06 RP11-467J12.4
189
 0.95
chr7_143579344_143579634 0.06 FAM115A
 family with sequence similarity 115, member A
 487
 0.8
chr15_23931247_23932124 0.06 NDN
 necdin, melanoma antigen (MAGE) family member
 765
 0.7
chr11_19420110_19420332 0.06 ENSG00000200687
 .
 3307
 0.25
chr9_109624363_109624788 0.06 ZNF462
 zinc finger protein 462
 803
 0.69
chr7_19408295_19408500 0.06 FERD3L
 Fer3-like bHLH transcription factor
 223353
 0.02
chr4_152148784_152149033 0.06 SH3D19
 SH3 domain containing 19
 274
 0.93
chr1_154941803_154941985 0.06 SHC1
 SHC (Src homology 2 domain containing) transforming protein 1
 525
 0.53
chr2_19557855_19558307 0.06 OSR1
 odd-skipped related transciption factor 1
 333
 0.92
chr9_89559920_89560071 0.06 GAS1
 growth arrest-specific 1
 2109
 0.48
chr5_3597166_3597716 0.06 IRX1
 iroquois homeobox 1
 1273
 0.51
chr1_151953452_151953706 0.06 S100A10
 S100 calcium binding protein A10
 11475
 0.14
chr8_93115764_93116215 0.06 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 475
 0.9
chr1_180882927_180883078 0.06 KIAA1614
 KIAA1614
 677
 0.71
chr9_91568737_91568931 0.06 C9orf47
 chromosome 9 open reading frame 47
 36944
 0.17
chr13_80824030_80824188 0.06 SPRY2
 sprouty homolog 2 (Drosophila)
 89685
 0.1
chr18_2906194_2907483 0.06 RP11-737O24.5
14126
 0.16
chr3_65583777_65583941 0.06 MAGI1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
 298
 0.95
chr6_3517843_3518042 0.06 SLC22A23
 solute carrier family 22, member 23
 60686
 0.14
chr1_162582264_162582415 0.06 DDR2
 discoidin domain receptor tyrosine kinase 2
 18824
 0.16
chr2_217180593_217180957 0.06 AC069155.1
12727
 0.18
chr13_76361393_76361544 0.06 LMO7
 LIM domain 7
 1506
 0.51
chr3_55519561_55519953 0.06 WNT5A
 wingless-type MMTV integration site family, member 5A
 1574
 0.4
chr1_8433877_8434267 0.06 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 9174
 0.19
chr1_157986336_157986537 0.05 KIRREL-IT1
 KIRREL intronic transcript 1 (non-protein coding)
 8904
 0.22
chr17_78044749_78045392 0.05 CCDC40
 coiled-coil domain containing 40
 12346
 0.15
chr6_147235797_147235979 0.05 STXBP5-AS1
 STXBP5 antisense RNA 1
 1133
 0.66
chr2_11051733_11051998 0.05 KCNF1
 potassium voltage-gated channel, subfamily F, member 1
 198
 0.95
chr10_98272514_98273588 0.05 TLL2
 tolloid-like 2
 617
 0.79
chr15_62862079_62862274 0.05 TLN2
 talin 2
 8612
 0.27
chr5_88178054_88178448 0.05 MEF2C
 myocyte enhancer factor 2C
 713
 0.52
chr16_88450130_88450579 0.05 ZNF469
 zinc finger protein 469
 43525
 0.15
chr8_38965103_38965508 0.05 ADAM32
 ADAM metallopeptidase domain 32
 13
 0.98
chr4_187901481_187901677 0.05 ENSG00000252382
 .
 122969
 0.06
chr7_94536809_94537187 0.05 PPP1R9A
 protein phosphatase 1, regulatory subunit 9A
 11
 0.99
chr1_215740105_215740888 0.05 KCTD3
 potassium channel tetramerization domain containing 3
 239
 0.96
chr1_170851017_170851182 0.05 MROH9
 maestro heat-like repeat family member 9
 53513
 0.16
chr8_121137253_121137925 0.05 COL14A1
 collagen, type XIV, alpha 1
 237
 0.96
chr2_235541588_235541739 0.05 ARL4C
 ADP-ribosylation factor-like 4C
 135966
 0.05
chr9_109876632_109876800 0.05 RP11-508N12.2
11447
 0.29
chr2_198909706_198909857 0.05 PLCL1
 phospholipase C-like 1
 38755
 0.22
chr2_175711229_175711408 0.05 CHN1
 chimerin 1
 175
 0.97
chr14_95949817_95950024 0.05 SYNE3
 spectrin repeat containing, nuclear envelope family member 3
 7747
 0.18
chr18_8707466_8707765 0.05 RP11-674N23.1
4
 0.73
chr16_10671409_10671697 0.05 RP11-27M24.2
487
 0.78
chr2_240230661_240230844 0.05 HDAC4
 histone deacetylase 4
 155
 0.95
chr12_91575790_91576058 0.05 DCN
 decorin
 505
 0.87
chr6_127839583_127839785 0.05 SOGA3
 SOGA family member 3
 352
 0.91
chr1_174081654_174081874 0.05 RABGAP1L
 RAB GTPase activating protein 1-like
 46784
 0.14
chr10_80009045_80009196 0.05 ENSG00000201393
 .
 118144
 0.06
chr15_40269217_40269368 0.05 EIF2AK4
 eukaryotic translation initiation factor 2 alpha kinase 4
 23116
 0.14
chr16_121633_122294 0.05 RHBDF1
 rhomboid 5 homolog 1 (Drosophila)
 666
 0.51
chr8_37556330_37556485 0.05 ZNF703
 zinc finger protein 703
 3138
 0.17
chr3_100852493_100852644 0.05 ENSG00000238312
 .
 68108
 0.12
chr9_97682991_97683218 0.05 RP11-54O15.3
14124
 0.17
chr6_113885726_113885909 0.05 ENSG00000266650
 .
 38300
 0.18
chr17_80970638_80970845 0.05 RP11-1197K16.2
31783
 0.15
chr8_124829147_124829427 0.05 FER1L6
 fer-1-like 6 (C. elegans)
 34940
 0.17
chr11_125365710_125366094 0.05 FEZ1
 fasciculation and elongation protein zeta 1 (zygin I)
 116
 0.91
chr11_121593168_121593875 0.05 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 132393
 0.05
chr8_18941319_18941572 0.05 PSD3
 pleckstrin and Sec7 domain containing 3
 795
 0.76
chr5_34487804_34487985 0.05 RAI14
 retinoic acid induced 14
 168448
 0.03
chr4_177712658_177713139 0.05 VEGFC
 vascular endothelial growth factor C
 983
 0.71
chr7_30952459_30952610 0.05 AQP1
 aquaporin 1 (Colton blood group)
 1064
 0.6
chr7_19136961_19137112 0.05 AC003986.6
15061
 0.16
chr5_150283969_150284454 0.05 ZNF300
 zinc finger protein 300
 140
 0.96
chr10_17241830_17242242 0.05 TRDMT1
 tRNA aspartic acid methyltransferase 1
 1543
 0.37
chr11_75272983_75274329 0.05 SERPINH1
 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
 216
 0.91
chr3_73652541_73652692 0.05 ENSG00000239119
 .
 9463
 0.21
chr3_189306684_189306989 0.05 TP63
 tumor protein p63
 42380
 0.21
chr5_171839559_171839710 0.05 ENSG00000216127
 .
 27124
 0.19
chr18_46020104_46020474 0.05 ENSG00000200872
 .
 18318
 0.21
chr1_34630860_34631011 0.05 CSMD2
 CUB and Sushi multiple domains 2
 60
 0.96
chr5_159305990_159306237 0.05 ADRA1B
 adrenoceptor alpha 1B
 37677
 0.2
chr18_56532811_56532962 0.05 ZNF532
 zinc finger protein 532
 100
 0.97
chr12_309110_309261 0.05 RP11-283I3.2
3623
 0.16
chr1_86859564_86859715 0.05 ODF2L
 outer dense fiber of sperm tails 2-like
 2021
 0.38
chrY_14075891_14076042 0.05 ENSG00000265161
 .
 128454
 0.06
chr8_87052179_87052395 0.05 PSKH2
 protein serine kinase H2
 29639
 0.19
chr1_173835540_173835691 0.05 ENSG00000234741
 .
 106
 0.88
chr22_25348691_25349626 0.05 KIAA1671
 KIAA1671
 461
 0.83
chr5_86478454_86478741 0.05 AC008394.1
 Uncharacterized protein
 56225
 0.12
chr18_12745437_12745588 0.05 ENSG00000201466
 .
 15204
 0.16
chr21_35133624_35133954 0.05 ITSN1
 intersectin 1 (SH3 domain protein)
 26443
 0.2
chr10_74544262_74544615 0.05 RP11-354E23.5
18120
 0.19
chr2_134325508_134325697 0.05 NCKAP5
 NCK-associated protein 5
 429
 0.88
chrX_90690422_90690847 0.05 PABPC5-AS1
 PABPC5 antisense RNA 1
 636
 0.54
chr10_3290980_3291169 0.05 PITRM1
 pitrilysin metallopeptidase 1
 76071
 0.11
chr4_111397420_111397787 0.05 ENPEP
 glutamyl aminopeptidase (aminopeptidase A)
 374
 0.89
chr7_3299969_3300120 0.05 SDK1
 sidekick cell adhesion molecule 1
 41036
 0.16
chr13_109740818_109740969 0.05 MYO16-AS2
 MYO16 antisense RNA 2
 13374
 0.3
chr8_71359441_71359951 0.05 ENSG00000253143
 .
 33026
 0.17
chr6_83073574_83074143 0.05 TPBG
 trophoblast glycoprotein
 103
 0.98
chr12_8012330_8012481 0.05 ENSG00000201663
 .
 8991
 0.12
chr18_59560344_59560906 0.05 RNF152
 ring finger protein 152
 367
 0.93
chr4_4862278_4863048 0.05 MSX1
 msh homeobox 1
 1270
 0.58
chr4_39525757_39525928 0.05 UGDH
 UDP-glucose 6-dehydrogenase
 2335
 0.24
chr10_52833938_52834229 0.05 PRKG1
 protein kinase, cGMP-dependent, type I
 149
 0.97
chr5_169230726_169230933 0.05 CTB-37A13.1
24460
 0.22
chr7_555957_556150 0.05 PDGFA
 platelet-derived growth factor alpha polypeptide
 2092
 0.33
chr11_101453394_101453891 0.05 TRPC6
 transient receptor potential cation channel, subfamily C, member 6
 592
 0.84
chr1_214722280_214722431 0.05 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 2211
 0.42
chr8_39966106_39966460 0.05 C8orf4
 chromosome 8 open reading frame 4
 44706
 0.18
chr3_114477226_114477377 0.05 ZBTB20
 zinc finger and BTB domain containing 20
 486
 0.86
chr17_1081882_1082496 0.05 ABR
 active BCR-related
 889
 0.58
chr5_150181131_150181300 0.05 AC010441.1
23348
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX2_CRX

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.1 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.0 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.0 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.0 GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus(GO:0002866)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.0 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0018995 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.0 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME PI 3K CASCADE Genes involved in PI-3K cascade
0.0 0.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation