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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for OVOL1

Z-value: 0.90

Motif logo

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Transcription factors associated with OVOL1

Gene Symbol Gene ID Gene Info
OVOL1
ENSG00000172818.5 ovo like transcriptional repressor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_65555266_65555920OVOL111000.277447-0.872.1e-03Click!
chr11_65553938_65554232OVOL14080.691119-0.723.0e-02Click!
chr11_65554622_65554896OVOL12660.812927-0.693.8e-02Click!
chr11_65560364_65560515OVOL17410.426536-0.098.3e-01Click!

Activity of the OVOL1 motif across conditions

Conditions sorted by the z-value of the OVOL1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_46177753_46179071 0.37 CBX1
 chromobox homolog 1
 148
 0.91
chr11_27491201_27491490 0.27 RP11-159H22.2
1931
 0.27
chr5_15510117_15510353 0.27 FBXL7
 F-box and leucine-rich repeat protein 7
 8688
 0.31
chr3_16219029_16219297 0.26 GALNT15
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
 2947
 0.33
chr18_5543806_5544379 0.24 EPB41L3
 erythrocyte membrane protein band 4.1-like 3
 149
 0.95
chrX_82764698_82764849 0.24 RP3-326L13.2
551
 0.75
chr3_112358958_112359194 0.24 CCDC80
 coiled-coil domain containing 80
 1040
 0.62
chr20_50178264_50178663 0.24 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
 705
 0.79
chr1_98515040_98515403 0.24 ENSG00000225206
 .
 3494
 0.38
chr18_48571368_48571694 0.24 SMAD4
 SMAD family member 4
 202
 0.96
chr6_154800959_154801329 0.23 CNKSR3
 CNKSR family member 3
 1519
 0.56
chr6_2789380_2789655 0.23 WRNIP1
 Werner helicase interacting protein 1
 20510
 0.17
chr18_43335869_43336020 0.22 RP11-116O18.3
8764
 0.2
chr8_20126437_20126669 0.22 LZTS1
 leucine zipper, putative tumor suppressor 1
 13750
 0.19
chr9_79451100_79451279 0.21 PRUNE2
 prune homolog 2 (Drosophila)
 69812
 0.12
chr3_197099341_197099661 0.21 ENSG00000238491
 .
 33079
 0.17
chr4_126602291_126602442 0.21 FAT4
 FAT atypical cadherin 4
 287275
 0.01
chr3_174157293_174157469 0.21 NAALADL2
 N-acetylated alpha-linked acidic dipeptidase-like 2
 1396
 0.61
chr7_77930640_77930829 0.21 RP5-1185I7.1
310997
 0.01
chr5_71544123_71544318 0.20 ENSG00000244748
 .
 66295
 0.09
chr2_202088333_202088488 0.20 CASP8
 caspase 8, apoptosis-related cysteine peptidase
 9756
 0.18
chr6_18434642_18434820 0.20 ENSG00000238458
 .
 32448
 0.19
chr2_19807945_19808132 0.19 OSR1
 odd-skipped related transciption factor 1
 249624
 0.02
chrX_33228916_33229133 0.19 DMD
 dystrophin
 405
 0.92
chr1_211589992_211590552 0.19 TRAF5
 TNF receptor-associated factor 5
 70566
 0.1
chr21_17566581_17566826 0.18 ENSG00000201025
 .
 90386
 0.1
chr7_120631344_120631706 0.18 CPED1
 cadherin-like and PC-esterase domain containing 1
 1849
 0.35
chr5_87972381_87972532 0.18 CTC-467M3.1
420
 0.85
chr21_36256046_36256553 0.18 RUNX1
 runt-related transcription factor 1
 3181
 0.38
chr2_17721828_17722425 0.18 VSNL1
 visinin-like 1
 163
 0.97
chr12_96580571_96580722 0.18 ELK3
 ELK3, ETS-domain protein (SRF accessory protein 2)
 7514
 0.22
chr8_86971534_86971711 0.18 ATP6V0D2
 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
 27930
 0.23
chr5_124748629_124749002 0.18 ENSG00000222107
 .
 61991
 0.16
chr22_29489752_29489903 0.17 CTA-747E2.10
17844
 0.13
chrX_9435964_9436115 0.17 TBL1X
 transducin (beta)-like 1X-linked
 2705
 0.43
chr1_101334241_101334590 0.17 EXTL2
 exostosin-like glycosyltransferase 2
 25805
 0.15
chr4_16619235_16619484 0.17 LDB2
 LIM domain binding 2
 21861
 0.28
chr7_84121800_84121951 0.17 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
 10
 0.99
chr17_41790734_41791669 0.17 ENSG00000215964
 .
 34367
 0.11
chr5_121409447_121409998 0.17 LOX
 lysyl oxidase
 4258
 0.27
chr10_99030444_99030681 0.16 ARHGAP19
 Rho GTPase activating protein 19
 141
 0.95
chr9_13034691_13034857 0.16 MPDZ
 multiple PDZ domain protein
 101406
 0.08
chr6_16337793_16338215 0.16 ENSG00000265642
 .
 90750
 0.08
chr19_48216774_48216947 0.16 EHD2
 EH-domain containing 2
 181
 0.93
chr9_12814147_12814330 0.15 RP11-3L8.3
106
 0.97
chr3_150138037_150138333 0.15 TSC22D2
 TSC22 domain family, member 2
 9389
 0.28
chr6_131360061_131360448 0.15 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 23272
 0.26
chr10_52567810_52567961 0.15 RP11-449O16.2
16400
 0.22
chr10_21803540_21803691 0.15 SKIDA1
 SKI/DACH domain containing 1
 3233
 0.17
chr6_117920563_117920770 0.15 GOPC
 golgi-associated PDZ and coiled-coil motif containing
 2861
 0.34
chr10_52984247_52984441 0.15 RP11-40C11.2
21222
 0.19
chr20_56827077_56827228 0.15 PPP4R1L
 protein phosphatase 4, regulatory subunit 1-like
 330
 0.9
chr7_55001398_55001578 0.15 ENSG00000252054
 .
 67977
 0.12
chr1_29066265_29066416 0.15 YTHDF2
 YTH domain family, member 2
 2863
 0.24
chr6_1256084_1256235 0.15 FOXQ1
 forkhead box Q1
 56516
 0.14
chr12_80080022_80080173 0.15 PAWR
 PRKC, apoptosis, WT1, regulator
 3763
 0.31
chr1_120217864_120218312 0.15 ZNF697
 zinc finger protein 697
 27692
 0.16
chr3_58067974_58068125 0.14 FLNB
 filamin B, beta
 3836
 0.31
chr16_83847696_83847847 0.14 HSBP1
 heat shock factor binding protein 1
 6177
 0.18
chr5_55705557_55705708 0.14 ENSG00000265665
 .
 47333
 0.14
chr12_64432896_64433047 0.14 SRGAP1
 SLIT-ROBO Rho GTPase activating protein 1
 56666
 0.11
chr13_43891097_43891540 0.14 ENOX1
 ecto-NOX disulfide-thiol exchanger 1
 43895
 0.21
chrX_84307873_84308024 0.14 APOOL
 apolipoprotein O-like
 49116
 0.16
chr14_69419003_69419387 0.14 ACTN1
 actinin, alpha 1
 4930
 0.26
chr2_142369486_142369637 0.14 ENSG00000265224
 .
 26852
 0.28
chr20_30930232_30930398 0.14 ASXL1
 additional sex combs like 1 (Drosophila)
 15840
 0.17
chr3_15724598_15724749 0.14 ENSG00000264354
 .
 14205
 0.18
chr10_12095697_12095857 0.14 UPF2
 UPF2 regulator of nonsense transcripts homolog (yeast)
 10754
 0.17
chr8_123605100_123605251 0.14 ENSG00000238901
 .
 78355
 0.11
chr8_90624271_90624438 0.14 RIPK2
 receptor-interacting serine-threonine kinase 2
 145621
 0.05
chr7_122314795_122315038 0.14 RNF133
 ring finger protein 133
 24294
 0.19
chr11_8789155_8789306 0.14 ST5
 suppression of tumorigenicity 5
 971
 0.37
chr2_196478572_196478732 0.14 SLC39A10
 solute carrier family 39 (zinc transporter), member 10
 37951
 0.19
chr5_78712289_78712440 0.14 HOMER1
 homer homolog 1 (Drosophila)
 96253
 0.07
chr5_67780816_67780967 0.13 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 192495
 0.03
chr1_178340504_178341006 0.13 RASAL2
 RAS protein activator like 2
 30149
 0.22
chr2_45805085_45805236 0.13 ENSG00000239396
 .
 8529
 0.22
chr3_112356424_112356629 0.13 CCDC80
 coiled-coil domain containing 80
 418
 0.88
chr7_90229787_90229938 0.13 AC002456.2
3195
 0.24
chr8_49834597_49834856 0.13 SNAI2
 snail family zinc finger 2
 427
 0.91
chr16_4909761_4909912 0.13 UBN1
 ubinuclein 1
 7620
 0.14
chr16_57226974_57227125 0.13 RSPRY1
 ring finger and SPRY domain containing 1
 6804
 0.14
chr9_34560276_34560427 0.13 CNTFR-AS1
 CNTFR antisense RNA 1
 7662
 0.11
chr8_127989678_127989829 0.13 ENSG00000212451
 .
 305986
 0.01
chr6_131290698_131290904 0.13 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 822
 0.76
chr11_106268675_106268826 0.13 RP11-680E19.1
133708
 0.05
chr6_20347614_20347765 0.13 E2F3
 E2F transcription factor 3
 54709
 0.12
chr10_31603702_31603954 0.13 ENSG00000237036
 .
 4033
 0.23
chr2_72684771_72684922 0.13 ENSG00000222536
 .
 264089
 0.02
chr1_15650263_15650414 0.13 RP3-467K16.7
11622
 0.16
chrX_19688369_19688923 0.13 SH3KBP1
 SH3-domain kinase binding protein 1
 166
 0.97
chr10_59997503_59997654 0.13 ENSG00000238970
 .
 943
 0.61
chr7_119913514_119913995 0.13 KCND2
 potassium voltage-gated channel, Shal-related subfamily, member 2
 32
 0.99
chrX_130912468_130912619 0.13 ENSG00000200587
 .
 160441
 0.04
chr5_158467035_158467186 0.13 CTD-2363C16.2
54296
 0.13
chr13_26312101_26312591 0.13 AL138815.1
 Uncharacterized protein
 129715
 0.05
chr2_54331076_54331227 0.12 ACYP2
 acylphosphatase 2, muscle type
 11389
 0.25
chrX_51638814_51638965 0.12 MAGED1
 melanoma antigen family D, 1
 2154
 0.37
chrX_33227444_33227711 0.12 DMD
 dystrophin
 1852
 0.53
chr11_27140156_27140307 0.12 BBOX1
 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
 63467
 0.13
chr5_151124636_151124864 0.12 ATOX1
 antioxidant 1 copper chaperone
 6929
 0.15
chr18_58201323_58201474 0.12 ENSG00000253011
 .
 20978
 0.26
chr3_189348802_189349006 0.12 TP63
 tumor protein p63
 312
 0.95
chr9_91609546_91609862 0.12 S1PR3
 sphingosine-1-phosphate receptor 3
 1717
 0.38
chr3_112931196_112931871 0.12 BOC
 BOC cell adhesion associated, oncogene regulated
 124
 0.97
chr12_118793748_118794037 0.12 TAOK3
 TAO kinase 3
 3018
 0.32
chr22_41613159_41613310 0.12 RP4-756G23.5
393
 0.76
chr16_18796482_18796633 0.12 RPS15A
 ribosomal protein S15a
 410
 0.8
chr2_145868497_145868648 0.12 ENSG00000253036
 .
 224066
 0.02
chr11_106031251_106031422 0.12 RP11-677I18.3
58634
 0.12
chr8_91996797_91997429 0.12 C8orf88
 chromosome 8 open reading frame 88
 372
 0.85
chr2_151439039_151439190 0.12 RND3
 Rho family GTPase 3
 43589
 0.22
chr7_50859293_50859444 0.12 GRB10
 growth factor receptor-bound protein 10
 1298
 0.58
chr16_10214963_10215114 0.12 GRIN2A
 glutamate receptor, ionotropic, N-methyl D-aspartate 2A
 59230
 0.14
chrX_34828763_34829004 0.12 FAM47B
 family with sequence similarity 47, member B
 132030
 0.06
chr8_30095301_30095452 0.12 RP11-51J9.4
56972
 0.12
chr1_119703325_119703476 0.12 RP11-418J17.1
14368
 0.21
chr6_139764774_139764925 0.11 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 69092
 0.13
chr16_88367140_88367361 0.11 ZNF469
 zinc finger protein 469
 126629
 0.05
chr10_64824310_64824738 0.11 ENSG00000199446
 .
 45375
 0.15
chr4_81186827_81187126 0.11 FGF5
 fibroblast growth factor 5
 777
 0.72
chr5_53383790_53383941 0.11 ENSG00000265421
 .
 12452
 0.25
chr5_162867024_162867396 0.11 CCNG1
 cyclin G1
 974
 0.44
chr4_81176376_81176527 0.11 FGF5
 fibroblast growth factor 5
 11302
 0.24
chr3_62174290_62174618 0.11 ENSG00000252184
 .
 70270
 0.12
chr16_24999768_24999967 0.11 ARHGAP17
 Rho GTPase activating protein 17
 26785
 0.22
chr12_13351879_13352395 0.11 EMP1
 epithelial membrane protein 1
 2417
 0.37
chr8_82124094_82124245 0.11 FABP5
 fatty acid binding protein 5 (psoriasis-associated)
 68429
 0.11
chr7_17347048_17347199 0.11 AC003075.4
8142
 0.23
chr3_159483781_159484285 0.11 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
 1141
 0.44
chr12_91502482_91502678 0.11 LUM
 lumican
 3028
 0.3
chr3_70576201_70576352 0.11 RP11-231I13.2
214399
 0.02
chr11_125497097_125497248 0.11 CHEK1
 checkpoint kinase 1
 529
 0.7
chr14_45712160_45712311 0.11 MIS18BP1
 MIS18 binding protein 1
 10145
 0.2
chr7_134469036_134469352 0.11 CALD1
 caldesmon 1
 4765
 0.32
chr11_108767349_108767500 0.11 ENSG00000201243
 .
 108820
 0.07
chr17_18362132_18362656 0.11 LGALS9C
 lectin, galactoside-binding, soluble, 9C
 17657
 0.11
chr4_124705698_124705849 0.11 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 384650
 0.01
chr4_160304105_160304256 0.11 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
 32800
 0.22
chr8_144512945_144513817 0.11 MAFA
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
 805
 0.48
chr3_157639138_157639289 0.11 ENSG00000251751
 .
 9301
 0.31
chrX_23686647_23686860 0.11 PRDX4
 peroxiredoxin 4
 1085
 0.58
chr4_53580350_53580621 0.11 ENSG00000212588
 .
 1069
 0.38
chr7_23511944_23512095 0.11 IGF2BP3
 insulin-like growth factor 2 mRNA binding protein 3
 1933
 0.3
chr2_232326502_232326776 0.11 ENSG00000202400
 .
 1488
 0.22
chr10_57391119_57391436 0.11 PCDH15
 protocadherin-related 15
 3575
 0.26
chr7_134540602_134540753 0.11 CALD1
 caldesmon 1
 10915
 0.29
chr7_134473160_134473311 0.11 CALD1
 caldesmon 1
 8806
 0.29
chr15_49967106_49967257 0.10 RP11-353B9.1
22845
 0.2
chr5_33148047_33148451 0.10 CTD-2203K17.1
292476
 0.01
chr4_88000475_88000743 0.10 AFF1
 AF4/FMR2 family, member 1
 29805
 0.23
chr13_23412141_23412547 0.10 ENSG00000253094
 .
 35060
 0.19
chr13_80658291_80658484 0.10 SPRY2
 sprouty homolog 2 (Drosophila)
 255407
 0.02
chr12_92488429_92488723 0.10 C12orf79
 chromosome 12 open reading frame 79
 42221
 0.15
chr4_74962901_74963052 0.10 CXCL2
 chemokine (C-X-C motif) ligand 2
 2034
 0.28
chr1_157013915_157014350 0.10 ARHGEF11
 Rho guanine nucleotide exchange factor (GEF) 11
 733
 0.68
chr1_115879628_115879779 0.10 NGF
 nerve growth factor (beta polypeptide)
 1154
 0.6
chr7_13960202_13960381 0.10 ETV1
 ets variant 1
 65775
 0.14
chr6_127498434_127498585 0.10 RSPO3
 R-spondin 3
 58326
 0.14
chr3_152314614_152314796 0.10 RP11-362A9.3
100103
 0.08
chr2_178453442_178453593 0.10 AC073834.3
14300
 0.18
chr17_35854577_35854849 0.10 DUSP14
 dual specificity phosphatase 14
 3143
 0.25
chr1_3816010_3816785 0.10 C1orf174
 chromosome 1 open reading frame 174
 452
 0.8
chr5_75903118_75903290 0.10 CTD-2236F14.1
1591
 0.31
chr5_151056524_151056678 0.10 CTB-113P19.1
67
 0.96
chr6_163951025_163951421 0.10 QKI
 QKI, KH domain containing, RNA binding
 4889
 0.36
chr15_71054590_71054766 0.10 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 1091
 0.55
chr6_100381252_100381443 0.10 MCHR2-AS1
 MCHR2 antisense RNA 1
 60473
 0.14
chr8_48436041_48436263 0.10 RP11-697N18.4
3807
 0.33
chr18_22929163_22929595 0.10 ZNF521
 zinc finger protein 521
 1778
 0.48
chr3_42066063_42066214 0.10 ULK4
 unc-51 like kinase 4
 62216
 0.12
chr1_212841074_212841261 0.10 ENSG00000207491
 .
 24439
 0.13
chr5_71127239_71127421 0.10 CARTPT
 CART prepropeptide
 112340
 0.07
chr20_50178684_50179923 0.10 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
 67
 0.99
chr13_45330241_45330498 0.10 ENSG00000238932
 .
 127560
 0.05
chr5_5419809_5420018 0.10 KIAA0947
 KIAA0947
 2894
 0.42
chr18_9619807_9620005 0.10 ENSG00000212572
 .
 1836
 0.31
chr4_183859496_183859668 0.10 DCTD
 dCMP deaminase
 20493
 0.24
chr20_9049976_9050220 0.10 PLCB4
 phospholipase C, beta 4
 350
 0.89
chr18_5500688_5500839 0.10 EPB41L3
 erythrocyte membrane protein band 4.1-like 3
 11394
 0.2
chr12_115889903_115890336 0.10 RP11-116D17.1
 HCG2038717; Uncharacterized protein
 89302
 0.1
chr7_4885363_4885579 0.10 RADIL
 Ras association and DIL domains
 7783
 0.17
chr9_8821970_8822217 0.10 ENSG00000239102
 .
 24958
 0.2
chr1_231964431_231964582 0.10 DISC1-IT1
 DISC1 intronic transcript 1 (non-protein coding)
 97074
 0.08
chr2_87551749_87551924 0.10 IGKV3OR2-268
 immunoglobulin kappa variable 3/OR2-268 (non-functional)
 13798
 0.29
chr6_143447345_143447496 0.10 AIG1
 androgen-induced 1
 33
 0.98
chr10_125608306_125608596 0.10 CPXM2
 carboxypeptidase X (M14 family), member 2
 42879
 0.15
chr5_141432956_141433107 0.10 GNPDA1
 glucosamine-6-phosphate deaminase 1
 40425
 0.13
chr16_70554540_70554691 0.10 COG4
 component of oligomeric golgi complex 4
 2488
 0.18
chr8_94934276_94934427 0.10 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
 2244
 0.3
chr17_70147844_70148239 0.10 SOX9
 SRY (sex determining region Y)-box 9
 30880
 0.25
chr3_57186762_57186915 0.10 IL17RD
 interleukin 17 receptor D
 10304
 0.19
chr17_2827552_2827726 0.10 CTD-3060P21.1
41550
 0.15
chr10_89629938_89630093 0.10 KLLN
 killin, p53-regulated DNA replication inhibitor
 6821
 0.14
chr2_157421974_157422125 0.10 AC011308.1
69394
 0.12
chr9_100465936_100466445 0.10 ENSG00000266608
 .
 3674
 0.21
chr14_20812432_20812706 0.10 RPPH1
 ribonuclease P RNA component H1
 725
 0.32
chr12_51008245_51008396 0.10 ENSG00000207136
 .
 18736
 0.2
chrX_125186493_125186644 0.10 DCAF12L2
 DDB1 and CUL4 associated factor 12-like 2
 113366
 0.07
chr12_32261770_32262117 0.10 RP11-843B15.2
1481
 0.38

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of OVOL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.0 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 0.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0090399 replicative senescence(GO:0090399)
0.0 0.0 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.0 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001940 male pronucleus(GO:0001940)
0.1 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity