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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for OVOL1

Z-value: 0.90

Motif logo

Transcription factors associated with OVOL1

Gene Symbol	Gene ID	Gene Info
OVOL1 Ensembl NCBI GeneCards UniProt	ENSG00000172818.5	OVOL1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
OVOL1	chr11_65555266_65555920	1100	0.277447	-0.87	2.1e-03	Click!
OVOL1	chr11_65553938_65554232	408	0.691119	-0.72	3.0e-02	Click!
OVOL1	chr11_65554622_65554896	266	0.812927	-0.69	3.8e-02	Click!
OVOL1	chr11_65560364_65560515	741	0.426536	-0.09	8.3e-01	Click!

Activity of the OVOL1 motif across conditions

Conditions sorted by the z-value of the OVOL1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_46177753_46179071	0.37	CBX1	chromobox homolog 1	148	0.91
chr11_27491201_27491490	0.27	RP11-159H22.2		1931	0.27
chr5_15510117_15510353	0.27	FBXL7	F-box and leucine-rich repeat protein 7	8688	0.31
chr3_16219029_16219297	0.26	GALNT15	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15	2947	0.33
chr18_5543806_5544379	0.24	EPB41L3	erythrocyte membrane protein band 4.1-like 3	149	0.95
chrX_82764698_82764849	0.24	RP3-326L13.2		551	0.75
chr3_112358958_112359194	0.24	CCDC80	coiled-coil domain containing 80	1040	0.62
chr20_50178264_50178663	0.24	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	705	0.79
chr1_98515040_98515403	0.24	ENSG00000225206	.	3494	0.38
chr18_48571368_48571694	0.24	SMAD4	SMAD family member 4	202	0.96
chr6_154800959_154801329	0.23	CNKSR3	CNKSR family member 3	1519	0.56
chr6_2789380_2789655	0.23	WRNIP1	Werner helicase interacting protein 1	20510	0.17
chr18_43335869_43336020	0.22	RP11-116O18.3		8764	0.2
chr8_20126437_20126669	0.22	LZTS1	leucine zipper, putative tumor suppressor 1	13750	0.19
chr9_79451100_79451279	0.21	PRUNE2	prune homolog 2 (Drosophila)	69812	0.12
chr3_197099341_197099661	0.21	ENSG00000238491	.	33079	0.17
chr4_126602291_126602442	0.21	FAT4	FAT atypical cadherin 4	287275	0.01
chr3_174157293_174157469	0.21	NAALADL2	N-acetylated alpha-linked acidic dipeptidase-like 2	1396	0.61
chr7_77930640_77930829	0.21	RP5-1185I7.1		310997	0.01
chr5_71544123_71544318	0.20	ENSG00000244748	.	66295	0.09
chr2_202088333_202088488	0.20	CASP8	caspase 8, apoptosis-related cysteine peptidase	9756	0.18
chr6_18434642_18434820	0.20	ENSG00000238458	.	32448	0.19
chr2_19807945_19808132	0.19	OSR1	odd-skipped related transciption factor 1	249624	0.02
chrX_33228916_33229133	0.19	DMD	dystrophin	405	0.92
chr1_211589992_211590552	0.19	TRAF5	TNF receptor-associated factor 5	70566	0.1
chr21_17566581_17566826	0.18	ENSG00000201025	.	90386	0.1
chr7_120631344_120631706	0.18	CPED1	cadherin-like and PC-esterase domain containing 1	1849	0.35
chr5_87972381_87972532	0.18	CTC-467M3.1		420	0.85
chr21_36256046_36256553	0.18	RUNX1	runt-related transcription factor 1	3181	0.38
chr2_17721828_17722425	0.18	VSNL1	visinin-like 1	163	0.97
chr12_96580571_96580722	0.18	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	7514	0.22
chr8_86971534_86971711	0.18	ATP6V0D2	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2	27930	0.23
chr5_124748629_124749002	0.18	ENSG00000222107	.	61991	0.16
chr22_29489752_29489903	0.17	CTA-747E2.10		17844	0.13
chrX_9435964_9436115	0.17	TBL1X	transducin (beta)-like 1X-linked	2705	0.43
chr1_101334241_101334590	0.17	EXTL2	exostosin-like glycosyltransferase 2	25805	0.15
chr4_16619235_16619484	0.17	LDB2	LIM domain binding 2	21861	0.28
chr7_84121800_84121951	0.17	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	10	0.99
chr17_41790734_41791669	0.17	ENSG00000215964	.	34367	0.11
chr5_121409447_121409998	0.17	LOX	lysyl oxidase	4258	0.27
chr10_99030444_99030681	0.16	ARHGAP19	Rho GTPase activating protein 19	141	0.95
chr9_13034691_13034857	0.16	MPDZ	multiple PDZ domain protein	101406	0.08
chr6_16337793_16338215	0.16	ENSG00000265642	.	90750	0.08
chr19_48216774_48216947	0.16	EHD2	EH-domain containing 2	181	0.93
chr9_12814147_12814330	0.15	RP11-3L8.3		106	0.97
chr3_150138037_150138333	0.15	TSC22D2	TSC22 domain family, member 2	9389	0.28
chr6_131360061_131360448	0.15	EPB41L2	erythrocyte membrane protein band 4.1-like 2	23272	0.26
chr10_52567810_52567961	0.15	RP11-449O16.2		16400	0.22
chr10_21803540_21803691	0.15	SKIDA1	SKI/DACH domain containing 1	3233	0.17
chr6_117920563_117920770	0.15	GOPC	golgi-associated PDZ and coiled-coil motif containing	2861	0.34
chr10_52984247_52984441	0.15	RP11-40C11.2		21222	0.19
chr20_56827077_56827228	0.15	PPP4R1L	protein phosphatase 4, regulatory subunit 1-like	330	0.9
chr7_55001398_55001578	0.15	ENSG00000252054	.	67977	0.12
chr1_29066265_29066416	0.15	YTHDF2	YTH domain family, member 2	2863	0.24
chr6_1256084_1256235	0.15	FOXQ1	forkhead box Q1	56516	0.14
chr12_80080022_80080173	0.15	PAWR	PRKC, apoptosis, WT1, regulator	3763	0.31
chr1_120217864_120218312	0.15	ZNF697	zinc finger protein 697	27692	0.16
chr3_58067974_58068125	0.14	FLNB	filamin B, beta	3836	0.31
chr16_83847696_83847847	0.14	HSBP1	heat shock factor binding protein 1	6177	0.18
chr5_55705557_55705708	0.14	ENSG00000265665	.	47333	0.14
chr12_64432896_64433047	0.14	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1	56666	0.11
chr13_43891097_43891540	0.14	ENOX1	ecto-NOX disulfide-thiol exchanger 1	43895	0.21
chrX_84307873_84308024	0.14	APOOL	apolipoprotein O-like	49116	0.16
chr14_69419003_69419387	0.14	ACTN1	actinin, alpha 1	4930	0.26
chr2_142369486_142369637	0.14	ENSG00000265224	.	26852	0.28
chr20_30930232_30930398	0.14	ASXL1	additional sex combs like 1 (Drosophila)	15840	0.17
chr3_15724598_15724749	0.14	ENSG00000264354	.	14205	0.18
chr10_12095697_12095857	0.14	UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)	10754	0.17
chr8_123605100_123605251	0.14	ENSG00000238901	.	78355	0.11
chr8_90624271_90624438	0.14	RIPK2	receptor-interacting serine-threonine kinase 2	145621	0.05
chr7_122314795_122315038	0.14	RNF133	ring finger protein 133	24294	0.19
chr11_8789155_8789306	0.14	ST5	suppression of tumorigenicity 5	971	0.37
chr2_196478572_196478732	0.14	SLC39A10	solute carrier family 39 (zinc transporter), member 10	37951	0.19
chr5_78712289_78712440	0.14	HOMER1	homer homolog 1 (Drosophila)	96253	0.07
chr5_67780816_67780967	0.13	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	192495	0.03
chr1_178340504_178341006	0.13	RASAL2	RAS protein activator like 2	30149	0.22
chr2_45805085_45805236	0.13	ENSG00000239396	.	8529	0.22
chr3_112356424_112356629	0.13	CCDC80	coiled-coil domain containing 80	418	0.88
chr7_90229787_90229938	0.13	AC002456.2		3195	0.24
chr8_49834597_49834856	0.13	SNAI2	snail family zinc finger 2	427	0.91
chr16_4909761_4909912	0.13	UBN1	ubinuclein 1	7620	0.14
chr16_57226974_57227125	0.13	RSPRY1	ring finger and SPRY domain containing 1	6804	0.14
chr9_34560276_34560427	0.13	CNTFR-AS1	CNTFR antisense RNA 1	7662	0.11
chr8_127989678_127989829	0.13	ENSG00000212451	.	305986	0.01
chr6_131290698_131290904	0.13	EPB41L2	erythrocyte membrane protein band 4.1-like 2	822	0.76
chr11_106268675_106268826	0.13	RP11-680E19.1		133708	0.05
chr6_20347614_20347765	0.13	E2F3	E2F transcription factor 3	54709	0.12
chr10_31603702_31603954	0.13	ENSG00000237036	.	4033	0.23
chr2_72684771_72684922	0.13	ENSG00000222536	.	264089	0.02
chr1_15650263_15650414	0.13	RP3-467K16.7		11622	0.16
chrX_19688369_19688923	0.13	SH3KBP1	SH3-domain kinase binding protein 1	166	0.97
chr10_59997503_59997654	0.13	ENSG00000238970	.	943	0.61
chr7_119913514_119913995	0.13	KCND2	potassium voltage-gated channel, Shal-related subfamily, member 2	32	0.99
chrX_130912468_130912619	0.13	ENSG00000200587	.	160441	0.04
chr5_158467035_158467186	0.13	CTD-2363C16.2		54296	0.13
chr13_26312101_26312591	0.13	AL138815.1	Uncharacterized protein	129715	0.05
chr2_54331076_54331227	0.12	ACYP2	acylphosphatase 2, muscle type	11389	0.25
chrX_51638814_51638965	0.12	MAGED1	melanoma antigen family D, 1	2154	0.37
chrX_33227444_33227711	0.12	DMD	dystrophin	1852	0.53
chr11_27140156_27140307	0.12	BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	63467	0.13
chr5_151124636_151124864	0.12	ATOX1	antioxidant 1 copper chaperone	6929	0.15
chr18_58201323_58201474	0.12	ENSG00000253011	.	20978	0.26
chr3_189348802_189349006	0.12	TP63	tumor protein p63	312	0.95
chr9_91609546_91609862	0.12	S1PR3	sphingosine-1-phosphate receptor 3	1717	0.38
chr3_112931196_112931871	0.12	BOC	BOC cell adhesion associated, oncogene regulated	124	0.97
chr12_118793748_118794037	0.12	TAOK3	TAO kinase 3	3018	0.32
chr22_41613159_41613310	0.12	RP4-756G23.5		393	0.76
chr16_18796482_18796633	0.12	RPS15A	ribosomal protein S15a	410	0.8
chr2_145868497_145868648	0.12	ENSG00000253036	.	224066	0.02
chr11_106031251_106031422	0.12	RP11-677I18.3		58634	0.12
chr8_91996797_91997429	0.12	C8orf88	chromosome 8 open reading frame 88	372	0.85
chr2_151439039_151439190	0.12	RND3	Rho family GTPase 3	43589	0.22
chr7_50859293_50859444	0.12	GRB10	growth factor receptor-bound protein 10	1298	0.58
chr16_10214963_10215114	0.12	GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	59230	0.14
chrX_34828763_34829004	0.12	FAM47B	family with sequence similarity 47, member B	132030	0.06
chr8_30095301_30095452	0.12	RP11-51J9.4		56972	0.12
chr1_119703325_119703476	0.12	RP11-418J17.1		14368	0.21
chr6_139764774_139764925	0.11	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	69092	0.13
chr16_88367140_88367361	0.11	ZNF469	zinc finger protein 469	126629	0.05
chr10_64824310_64824738	0.11	ENSG00000199446	.	45375	0.15
chr4_81186827_81187126	0.11	FGF5	fibroblast growth factor 5	777	0.72
chr5_53383790_53383941	0.11	ENSG00000265421	.	12452	0.25
chr5_162867024_162867396	0.11	CCNG1	cyclin G1	974	0.44
chr4_81176376_81176527	0.11	FGF5	fibroblast growth factor 5	11302	0.24
chr3_62174290_62174618	0.11	ENSG00000252184	.	70270	0.12
chr16_24999768_24999967	0.11	ARHGAP17	Rho GTPase activating protein 17	26785	0.22
chr12_13351879_13352395	0.11	EMP1	epithelial membrane protein 1	2417	0.37
chr8_82124094_82124245	0.11	FABP5	fatty acid binding protein 5 (psoriasis-associated)	68429	0.11
chr7_17347048_17347199	0.11	AC003075.4		8142	0.23
chr3_159483781_159484285	0.11	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough	1141	0.44
chr12_91502482_91502678	0.11	LUM	lumican	3028	0.3
chr3_70576201_70576352	0.11	RP11-231I13.2		214399	0.02
chr11_125497097_125497248	0.11	CHEK1	checkpoint kinase 1	529	0.7
chr14_45712160_45712311	0.11	MIS18BP1	MIS18 binding protein 1	10145	0.2
chr7_134469036_134469352	0.11	CALD1	caldesmon 1	4765	0.32
chr11_108767349_108767500	0.11	ENSG00000201243	.	108820	0.07
chr17_18362132_18362656	0.11	LGALS9C	lectin, galactoside-binding, soluble, 9C	17657	0.11
chr4_124705698_124705849	0.11	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	384650	0.01
chr4_160304105_160304256	0.11	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	32800	0.22
chr8_144512945_144513817	0.11	MAFA	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A	805	0.48
chr3_157639138_157639289	0.11	ENSG00000251751	.	9301	0.31
chrX_23686647_23686860	0.11	PRDX4	peroxiredoxin 4	1085	0.58
chr4_53580350_53580621	0.11	ENSG00000212588	.	1069	0.38
chr7_23511944_23512095	0.11	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3	1933	0.3
chr2_232326502_232326776	0.11	ENSG00000202400	.	1488	0.22
chr10_57391119_57391436	0.11	PCDH15	protocadherin-related 15	3575	0.26
chr7_134540602_134540753	0.11	CALD1	caldesmon 1	10915	0.29
chr7_134473160_134473311	0.11	CALD1	caldesmon 1	8806	0.29
chr15_49967106_49967257	0.10	RP11-353B9.1		22845	0.2
chr5_33148047_33148451	0.10	CTD-2203K17.1		292476	0.01
chr4_88000475_88000743	0.10	AFF1	AF4/FMR2 family, member 1	29805	0.23
chr13_23412141_23412547	0.10	ENSG00000253094	.	35060	0.19
chr13_80658291_80658484	0.10	SPRY2	sprouty homolog 2 (Drosophila)	255407	0.02
chr12_92488429_92488723	0.10	C12orf79	chromosome 12 open reading frame 79	42221	0.15
chr4_74962901_74963052	0.10	CXCL2	chemokine (C-X-C motif) ligand 2	2034	0.28
chr1_157013915_157014350	0.10	ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	733	0.68
chr1_115879628_115879779	0.10	NGF	nerve growth factor (beta polypeptide)	1154	0.6
chr7_13960202_13960381	0.10	ETV1	ets variant 1	65775	0.14
chr6_127498434_127498585	0.10	RSPO3	R-spondin 3	58326	0.14
chr3_152314614_152314796	0.10	RP11-362A9.3		100103	0.08
chr2_178453442_178453593	0.10	AC073834.3		14300	0.18
chr17_35854577_35854849	0.10	DUSP14	dual specificity phosphatase 14	3143	0.25
chr1_3816010_3816785	0.10	C1orf174	chromosome 1 open reading frame 174	452	0.8
chr5_75903118_75903290	0.10	CTD-2236F14.1		1591	0.31
chr5_151056524_151056678	0.10	CTB-113P19.1		67	0.96
chr6_163951025_163951421	0.10	QKI	QKI, KH domain containing, RNA binding	4889	0.36
chr15_71054590_71054766	0.10	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	1091	0.55
chr6_100381252_100381443	0.10	MCHR2-AS1	MCHR2 antisense RNA 1	60473	0.14
chr8_48436041_48436263	0.10	RP11-697N18.4		3807	0.33
chr18_22929163_22929595	0.10	ZNF521	zinc finger protein 521	1778	0.48
chr3_42066063_42066214	0.10	ULK4	unc-51 like kinase 4	62216	0.12
chr1_212841074_212841261	0.10	ENSG00000207491	.	24439	0.13
chr5_71127239_71127421	0.10	CARTPT	CART prepropeptide	112340	0.07
chr20_50178684_50179923	0.10	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	67	0.99
chr13_45330241_45330498	0.10	ENSG00000238932	.	127560	0.05
chr5_5419809_5420018	0.10	KIAA0947	KIAA0947	2894	0.42
chr18_9619807_9620005	0.10	ENSG00000212572	.	1836	0.31
chr4_183859496_183859668	0.10	DCTD	dCMP deaminase	20493	0.24
chr20_9049976_9050220	0.10	PLCB4	phospholipase C, beta 4	350	0.89
chr18_5500688_5500839	0.10	EPB41L3	erythrocyte membrane protein band 4.1-like 3	11394	0.2
chr12_115889903_115890336	0.10	RP11-116D17.1	HCG2038717; Uncharacterized protein	89302	0.1
chr7_4885363_4885579	0.10	RADIL	Ras association and DIL domains	7783	0.17
chr9_8821970_8822217	0.10	ENSG00000239102	.	24958	0.2
chr1_231964431_231964582	0.10	DISC1-IT1	DISC1 intronic transcript 1 (non-protein coding)	97074	0.08
chr2_87551749_87551924	0.10	IGKV3OR2-268	immunoglobulin kappa variable 3/OR2-268 (non-functional)	13798	0.29
chr6_143447345_143447496	0.10	AIG1	androgen-induced 1	33	0.98
chr10_125608306_125608596	0.10	CPXM2	carboxypeptidase X (M14 family), member 2	42879	0.15
chr5_141432956_141433107	0.10	GNPDA1	glucosamine-6-phosphate deaminase 1	40425	0.13
chr16_70554540_70554691	0.10	COG4	component of oligomeric golgi complex 4	2488	0.18
chr8_94934276_94934427	0.10	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1	2244	0.3
chr17_70147844_70148239	0.10	SOX9	SRY (sex determining region Y)-box 9	30880	0.25
chr3_57186762_57186915	0.10	IL17RD	interleukin 17 receptor D	10304	0.19
chr17_2827552_2827726	0.10	CTD-3060P21.1		41550	0.15
chr10_89629938_89630093	0.10	KLLN	killin, p53-regulated DNA replication inhibitor	6821	0.14
chr2_157421974_157422125	0.10	AC011308.1		69394	0.12
chr9_100465936_100466445	0.10	ENSG00000266608	.	3674	0.21
chr14_20812432_20812706	0.10	RPPH1	ribonuclease P RNA component H1	725	0.32
chr12_51008245_51008396	0.10	ENSG00000207136	.	18736	0.2
chrX_125186493_125186644	0.10	DCAF12L2	DDB1 and CUL4 associated factor 12-like 2	113366	0.07
chr12_32261770_32262117	0.10	RP11-843B15.2		1481	0.38

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of OVOL1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0048859	formation of anatomical boundary(GO:0048859)
0.1	0.2	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.0	0.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.5	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.0	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.0	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.1	GO:0007619	courtship behavior(GO:0007619)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.0	0.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.0	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.0	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0090399	replicative senescence(GO:0090399)
0.0	0.0	GO:0033024	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.2	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.0	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.0	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.0	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.3	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.0	GO:0006011	UDP-glucose metabolic process(GO:0006011)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0001940	male pronucleus(GO:0001940)
0.1	0.3	GO:0033270	paranode region of axon(GO:0033270)
0.1	0.2	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.2	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.3	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.3	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.0	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.0	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity