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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PAX3

Z-value: 1.86

Motif logo

Transcription factors associated with PAX3

Gene Symbol	Gene ID	Gene Info
PAX3 Ensembl NCBI GeneCards UniProt	ENSG00000135903.14	PAX3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
PAX3	chr2_223163398_223163549	2	0.926615	0.62	7.3e-02	Click!
PAX3	chr2_223163063_223163341	263	0.571001	0.48	1.9e-01	Click!
PAX3	chr2_223164692_223164843	1052	0.468249	0.43	2.5e-01	Click!
PAX3	chr2_223163730_223163962	131	0.927175	0.33	3.9e-01	Click!

Activity of the PAX3 motif across conditions

Conditions sorted by the z-value of the PAX3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_57182553_57183430	1.30	ZNF835	zinc finger protein 835	137	0.95
chr5_33891538_33892159	1.06	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12	198	0.94
chr2_202901871_202902113	0.78	FZD7	frizzled family receptor 7	2682	0.25
chr1_38412223_38412952	0.66	INPP5B	inositol polyphosphate-5-phosphatase, 75kDa	136	0.94
chr7_15725092_15725754	0.65	MEOX2	mesenchyme homeobox 2	1014	0.63
chr5_172306134_172306575	0.63	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	25866	0.16
chr8_106645652_106645917	0.63	RP11-642D21.1		36435	0.19
chr12_115118702_115118853	0.56	TBX3	T-box 3	2618	0.32
chr5_38421113_38421302	0.55	EGFLAM-AS1	EGFLAM antisense RNA 1	6271	0.17
chr15_48935948_48936126	0.52	FBN1	fibrillin 1	1881	0.46
chr4_119273101_119273655	0.52	PRSS12	protease, serine, 12 (neurotrypsin, motopsin)	780	0.76
chr7_41738896_41739123	0.52	INHBA	inhibin, beta A	1198	0.49
chr1_84878194_84878394	0.50	DNASE2B	deoxyribonuclease II beta	4381	0.25
chr18_56244152_56244311	0.50	RP11-126O1.2		19929	0.14
chr11_94528525_94528870	0.50	AMOTL1	angiomotin like 1	27160	0.2
chr9_91793130_91793737	0.49	SHC3	SHC (Src homology 2 domain containing) transforming protein 3	249	0.95
chr17_13265618_13265967	0.49	ENSG00000266115	.	137853	0.05
chr10_112411260_112411724	0.49	RBM20	RNA binding motif protein 20	7337	0.16
chr6_125698814_125699135	0.49	RP11-735G4.1		3504	0.35
chr8_45775_45926	0.49	AC144568.2	Uncharacterized protein	23233	0.21
chr3_112356638_112356789	0.48	CCDC80	coiled-coil domain containing 80	231	0.95
chr14_101294075_101294314	0.48	AL117190.2		1343	0.15
chr12_15941079_15941239	0.48	EPS8	epidermal growth factor receptor pathway substrate 8	1156	0.62
chr6_28176044_28176266	0.47	ZSCAN9	zinc finger and SCAN domain containing 9	16509	0.13
chr5_148787780_148787931	0.47	ENSG00000208035	.	20626	0.11
chr3_98619314_98619465	0.47	DCBLD2	discoidin, CUB and LCCL domain containing 2	626	0.66
chr15_61497485_61497898	0.46	RP11-39M21.2		6421	0.23
chr9_14096707_14097036	0.46	NFIB	nuclear factor I/B	83920	0.11
chr13_40976108_40976619	0.45	ENSG00000252812	.	5214	0.32
chr6_148829582_148830289	0.45	ENSG00000223322	.	15441	0.29
chr3_114343374_114343541	0.45	ZBTB20	zinc finger and BTB domain containing 20	335	0.94
chr6_683619_684080	0.44	EXOC2	exocyst complex component 2	9262	0.26
chr12_39538930_39539305	0.44	KIF21A	kinesin family member 21A	187012	0.03
chr14_45433529_45433743	0.44	FAM179B	family with sequence similarity 179, member B	2194	0.25
chr4_85888141_85888634	0.43	WDFY3	WD repeat and FYVE domain containing 3	843	0.73
chr18_19754824_19754975	0.43	RP11-627G18.2		1724	0.27
chr7_93552513_93552820	0.43	GNG11	guanine nucleotide binding protein (G protein), gamma 11	1655	0.33
chr11_33398887_33399038	0.43	ENSG00000223134	.	22951	0.23
chrX_102659686_102660224	0.43	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	27846	0.15
chr4_176922498_176923243	0.42	GPM6A	glycoprotein M6A	613	0.78
chr14_85995700_85996361	0.42	FLRT2	fibronectin leucine rich transmembrane protein 2	458	0.75
chr12_107352268_107352490	0.42	C12orf23	chromosome 12 open reading frame 23	1816	0.3
chr7_134464463_134465343	0.42	CALD1	caldesmon 1	474	0.89
chr10_17273946_17274204	0.42	VIM	vimentin	1467	0.3
chr18_51885533_51885684	0.41	C18orf54	chromosome 18 open reading frame 54	653	0.63
chr13_33858654_33859881	0.41	STARD13	StAR-related lipid transfer (START) domain containing 13	625	0.76
chr8_15094580_15095009	0.41	SGCZ	sarcoglycan, zeta	1054	0.7
chr6_148679615_148679766	0.41	SASH1	SAM and SH3 domain containing 1	15961	0.25
chr4_113811114_113811345	0.41	RP11-119H12.6		7743	0.26
chr4_114398278_114398429	0.41	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	36645	0.17
chr2_179070529_179070680	0.41	OSBPL6	oxysterol binding protein-like 6	11228	0.22
chr6_112884624_112884775	0.41	ENSG00000252215	.	31315	0.22
chr14_103673729_103674048	0.41	ENSG00000239117	.	4365	0.24
chrX_117250951_117251414	0.40	KLHL13	kelch-like family member 13	121	0.98
chr4_77674025_77674176	0.40	RP11-359D14.2		5527	0.24
chr7_32099128_32099768	0.40	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	11013	0.32
chr10_86185479_86185663	0.40	CCSER2	coiled-coil serine-rich protein 2	876	0.74
chr4_77905705_77905940	0.40	SEPT11	septin 11	355	0.91
chr12_72724242_72724393	0.40	ENSG00000236333	.	55630	0.15
chr1_78355069_78355375	0.40	NEXN-AS1	NEXN antisense RNA 1	2	0.95
chr2_86225577_86226007	0.40	POLR1A	polymerase (RNA) I polypeptide A, 194kDa	107486	0.05
chr16_88219567_88219948	0.39	BANP	BTG3 associated nuclear protein	216133	0.02
chr12_78334342_78334902	0.39	NAV3	neuron navigator 3	25434	0.27
chr14_69657871_69659182	0.39	EXD2	exonuclease 3'-5' domain containing 2	3	0.98
chr16_56423787_56423938	0.39	AMFR	autocrine motility factor receptor, E3 ubiquitin protein ligase	13153	0.13
chr17_19289644_19289962	0.39	MFAP4	microfibrillar-associated protein 4	442	0.7
chr16_55542879_55544136	0.39	LPCAT2	lysophosphatidylcholine acyltransferase 2	597	0.77
chr9_103190353_103190767	0.39	MSANTD3	Myb/SANT-like DNA-binding domain containing 3	841	0.58
chr1_242310080_242310365	0.38	RP11-561I11.4		594	0.75
chr6_145469120_145469400	0.38	ENSG00000221796	.	200634	0.03
chr6_76645073_76645368	0.38	IMPG1	interphotoreceptor matrix proteoglycan 1	454	0.81
chr3_98618719_98618976	0.38	DCBLD2	discoidin, CUB and LCCL domain containing 2	1168	0.44
chr12_111264822_111264977	0.38	CCDC63	coiled-coil domain containing 63	19865	0.21
chrX_53349448_53350467	0.38	IQSEC2	IQ motif and Sec7 domain 2	565	0.73
chr3_147140468_147140953	0.38	ZIC1	Zic family member 1	13539	0.19
chr10_93643349_93643523	0.37	RP11-402D21.2		24452	0.16
chr3_149864938_149865143	0.37	RP11-167H9.4		49221	0.15
chr11_75315135_75315603	0.37	CTD-2530H12.8		7054	0.14
chr5_172752767_172752937	0.37	STC2	stanniocalcin 2	948	0.57
chr6_42672111_42672366	0.37	PRPH2	peripherin 2 (retinal degeneration, slow)	18074	0.16
chr2_8260069_8260430	0.37	ENSG00000221255	.	543277	0.0
chr3_173114984_173115853	0.37	NLGN1	neuroligin 1	152	0.98
chr3_197081522_197081710	0.37	ENSG00000238491	.	15194	0.2
chr9_124506702_124506934	0.36	DAB2IP	DAB2 interacting protein	1754	0.47
chr8_12985771_12986032	0.36	DLC1	deleted in liver cancer 1	5082	0.26
chr6_5498765_5499077	0.36	RP1-232P20.1		40613	0.2
chr1_229100194_229100345	0.36	RHOU	ras homolog family member U	229445	0.02
chr12_109226312_109226796	0.36	ENSG00000207622	.	4228	0.18
chr12_175122_175459	0.36	IQSEC3	IQ motif and Sec7 domain 3	641	0.71
chr4_107956832_107957922	0.35	DKK2	dickkopf WNT signaling pathway inhibitor 2	77	0.99
chr15_96881380_96881711	0.35	ENSG00000222651	.	5055	0.17
chr6_152084748_152085135	0.35	ESR1	estrogen receptor 1	40625	0.17
chr2_218806750_218806920	0.35	TNS1	tensin 1	1958	0.38
chr4_160188761_160189259	0.35	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	121	0.97
chr16_14097015_14097289	0.35	CTD-2135D7.2		67660	0.11
chr14_51133209_51133360	0.35	SAV1	salvador homolog 1 (Drosophila)	1057	0.46
chr22_46473276_46473626	0.35	FLJ27365	hsa-mir-4763	2741	0.14
chr3_173114310_173114533	0.35	NLGN1	neuroligin 1	347	0.94
chr1_201914320_201914471	0.35	LMOD1	leiomodin 1 (smooth muscle)	1320	0.3
chr2_133426336_133426487	0.35	LYPD1	LY6/PLAUR domain containing 1	1367	0.49
chr2_16831792_16832248	0.35	FAM49A	family with sequence similarity 49, member A	15076	0.3
chr7_19048965_19049132	0.35	AC003986.6		103049	0.06
chr3_175244326_175245006	0.35	ENSG00000201648	.	82601	0.1
chr20_30457693_30458808	0.34	DUSP15	dual specificity phosphatase 15	125	0.67
chr7_41735925_41736162	0.34	INHBA-AS1	INHBA antisense RNA 1	2497	0.29
chr12_93162973_93163124	0.34	PLEKHG7	pleckstrin homology domain containing, family G (with RhoGef domain) member 7	32737	0.18
chr9_21688149_21688723	0.33	ENSG00000244230	.	10877	0.24
chr5_92943709_92943997	0.33	ENSG00000251725	.	12641	0.2
chr6_116882462_116882643	0.33	FAM26D	family with sequence similarity 26, member D	7639	0.14
chr1_242097620_242097936	0.33	EXO1	exonuclease 1	55436	0.13
chr10_30842846_30843212	0.33	ENSG00000239744	.	1804	0.44
chr3_25472946_25473178	0.33	RARB	retinoic acid receptor, beta	3260	0.35
chr3_100711576_100712203	0.33	ABI3BP	ABI family, member 3 (NESH) binding protein	408	0.89
chr6_77743639_77743821	0.33	HTR1B	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	429760	0.01
chr2_220942198_220942388	0.32	ENSG00000221199	.	114306	0.06
chr18_57326676_57327097	0.32	CCBE1	collagen and calcium binding EGF domains 1	6508	0.21
chr15_90543166_90543622	0.32	ZNF710	zinc finger protein 710	1230	0.4
chr4_183047320_183047598	0.32	AC108142.1		17470	0.17
chr6_148829356_148829537	0.32	ENSG00000223322	.	15930	0.29
chr8_105373162_105373361	0.32	DCSTAMP	dendrocyte expressed seven transmembrane protein	12492	0.2
chr2_210799016_210799362	0.32	UNC80	unc-80 homolog (C. elegans)	25058	0.21
chr2_134432894_134433053	0.32	ENSG00000200708	.	79311	0.11
chr3_162210287_162210563	0.32	ENSG00000238398	.	686338	0.0
chr20_6514663_6515268	0.32	BMP2	bone morphogenetic protein 2	233346	0.02
chr9_137437911_137438062	0.32	COL5A1	collagen, type V, alpha 1	95634	0.07
chr1_79471738_79472138	0.32	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1	465	0.9
chr6_15505544_15505788	0.32	DTNBP1	dystrobrevin binding protein 1	42927	0.19
chr5_133775184_133775365	0.32	CDKN2AIPNL	CDKN2A interacting protein N-terminal like	27685	0.14
chr2_107502151_107502302	0.32	ST6GAL2	ST6 beta-galactosamide alpha-2,6-sialyltranferase 2	243	0.95
chr10_26846446_26846738	0.32	ENSG00000199733	.	48074	0.17
chr5_120114458_120114855	0.32	ENSG00000222609	.	68121	0.14
chr3_158508847_158509075	0.31	RP11-379F4.8		8625	0.16
chr16_25005350_25005552	0.31	ARHGAP17	Rho GTPase activating protein 17	21201	0.24
chr20_25566355_25566601	0.31	NINL	ninein-like	325	0.88
chr4_173973205_173973433	0.31	ENSG00000241652	.	89475	0.09
chr6_28183539_28183724	0.31	ZSCAN9	zinc finger and SCAN domain containing 9	9033	0.14
chr3_81772804_81773074	0.31	GBE1	glucan (1,4-alpha-), branching enzyme 1	19841	0.3
chr5_121417237_121417571	0.31	LOX	lysyl oxidase	3424	0.28
chr9_90113946_90114123	0.31	DAPK1	death-associated protein kinase 1	114	0.98
chr5_77843393_77843700	0.31	LHFPL2	lipoma HMGIC fusion partner-like 2	1428	0.58
chr19_9454091_9454242	0.31	ZNF559	zinc finger protein 559	4234	0.15
chr10_98751300_98751521	0.31	RP11-175O19.4		797	0.65
chr7_94029074_94029225	0.31	COL1A2	collagen, type I, alpha 2	5276	0.3
chr6_4906745_4907027	0.31	CDYL	chromodomain protein, Y-like	16660	0.25
chr2_43861781_43861952	0.31	PLEKHH2	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2	2546	0.29
chr12_101188772_101189038	0.31	ANO4	anoctamin 4	169	0.97
chr9_107826300_107826627	0.31	ENSG00000201583	.	32574	0.22
chr13_24145710_24146057	0.31	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1080	0.66
chr7_143347472_143347849	0.31	FAM115C	family with sequence similarity 115, member C	29115	0.16
chr3_149094037_149094204	0.31	TM4SF1	transmembrane 4 L six family member 1	621	0.64
chr5_82768204_82768925	0.31	VCAN	versican	820	0.75
chrX_139847648_139847972	0.30	CDR1	cerebellar degeneration-related protein 1, 34kDa	18913	0.23
chr1_95389567_95389941	0.30	CNN3	calponin 3, acidic	1583	0.36
chr11_73849946_73850148	0.30	C2CD3	C2 calcium-dependent domain containing 3	31982	0.14
chr10_63812743_63812894	0.30	ARID5B	AT rich interactive domain 5B (MRF1-like)	3848	0.32
chr2_239553535_239553686	0.30	TWIST2	twist family bHLH transcription factor 2	203063	0.02
chrX_34675593_34676078	0.30	TMEM47	transmembrane protein 47	430	0.92
chr2_38300771_38301295	0.30	CYP1B1-AS1	CYP1B1 antisense RNA 1	1758	0.3
chr16_57513431_57513689	0.30	DOK4	docking protein 4	157	0.93
chr7_134472487_134472744	0.30	CALD1	caldesmon 1	8186	0.3
chr1_215179099_215179440	0.30	KCNK2	potassium channel, subfamily K, member 2	71	0.99
chr17_18906037_18906188	0.30	FAM83G	family with sequence similarity 83, member G	1377	0.32
chr11_121680889_121681086	0.30	ENSG00000252556	.	194076	0.03
chr10_133793290_133793613	0.30	BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	1976	0.41
chr4_114897314_114897610	0.30	ARSJ	arylsulfatase family, member J	2690	0.37
chr18_73168325_73168501	0.30	SMIM21	small integral membrane protein 21	28755	0.22
chr15_63446474_63446661	0.30	RPS27L	ribosomal protein S27-like	2406	0.28
chr7_94028286_94028494	0.30	COL1A2	collagen, type I, alpha 2	4517	0.32
chr13_30002091_30002575	0.30	MTUS2	microtubule associated tumor suppressor candidate 2	431	0.89
chr3_182941566_182941717	0.30	B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	29391	0.16
chr1_33876024_33876604	0.29	PHC2	polyhomeotic homolog 2 (Drosophila)	19902	0.15
chrX_107682801_107683045	0.29	COL4A5	collagen, type IV, alpha 5	189	0.54
chr13_107124235_107124715	0.29	EFNB2	ephrin-B2	62987	0.14
chr8_128940725_128940922	0.29	TMEM75	transmembrane protein 75	19768	0.19
chr11_67139277_67139428	0.29	CLCF1	cardiotrophin-like cytokine factor 1	1856	0.16
chr8_107071271_107071422	0.29	ENSG00000251003	.	1325	0.61
chr6_114182367_114182913	0.29	MARCKS	myristoylated alanine-rich protein kinase C substrate	4099	0.23
chr12_54611339_54611663	0.29	ENSG00000265371	.	13759	0.1
chr3_173302379_173302636	0.29	NLGN1	neuroligin 1	162	0.98
chr6_10555958_10556148	0.29	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)	187	0.95
chr6_165722551_165723097	0.29	C6orf118	chromosome 6 open reading frame 118	272	0.95
chr3_25534648_25534799	0.29	RARB	retinoic acid receptor, beta	34922	0.19
chr1_214491340_214491539	0.29	SMYD2	SET and MYND domain containing 2	12881	0.25
chr10_33622471_33622736	0.29	NRP1	neuropilin 1	707	0.77
chr8_13224635_13224889	0.29	RP11-10C8.2		28679	0.23
chr7_90794067_90794435	0.29	FZD1	frizzled family receptor 1	99532	0.09
chr4_111397030_111397405	0.29	ENPEP	glutamyl aminopeptidase (aminopeptidase A)	12	0.98
chr7_80547175_80548098	0.29	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	863	0.76
chr7_42882790_42882963	0.29	C7orf25	chromosome 7 open reading frame 25	68633	0.11
chr15_39878902_39879188	0.29	THBS1	thrombospondin 1	5751	0.2
chr4_148261664_148261815	0.29	ENSG00000221369	.	4130	0.35
chr16_29231551_29231794	0.28	RP11-231C14.6		91999	0.06
chr5_92498163_92498415	0.28	ENSG00000237187	.	259830	0.02
chr4_72897506_72897709	0.28	NPFFR2	neuropeptide FF receptor 2	12	0.99
chr5_33852508_33852730	0.28	ENSG00000201623	.	35648	0.17
chr9_12776208_12776436	0.28	LURAP1L	leucine rich adaptor protein 1-like	1302	0.47
chr2_190043558_190043796	0.28	COL5A2	collagen, type V, alpha 2	928	0.65
chr6_85823864_85824548	0.28	NT5E	5'-nucleotidase, ecto (CD73)	335603	0.01
chr15_30112674_30113382	0.28	TJP1	tight junction protein 1	723	0.64
chr7_92327766_92328157	0.28	ENSG00000206763	.	3167	0.33

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.2	0.7	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.5	GO:0060596	mammary placode formation(GO:0060596)
0.2	0.7	GO:0001757	somite specification(GO:0001757)
0.1	0.6	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.3	GO:0031223	auditory behavior(GO:0031223)
0.1	0.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.4	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.4	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.1	0.3	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.4	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.3	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.3	GO:0046083	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1	0.3	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1	0.3	GO:0060435	bronchiole development(GO:0060435)
0.1	0.4	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.3	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.3	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1	0.2	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.2	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.3	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.2	GO:0060437	lung growth(GO:0060437)
0.1	0.1	GO:0010996	response to auditory stimulus(GO:0010996)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.2	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.1	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.1	0.1	GO:0060510	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.1	0.5	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.3	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.2	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.3	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1	0.2	GO:0072033	renal vesicle formation(GO:0072033)
0.1	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.2	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	0.1	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1	0.2	GO:0070141	response to UV-A(GO:0070141)
0.1	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.1	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	0.2	GO:0010842	retina layer formation(GO:0010842)
0.1	0.1	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.2	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:1903726	negative regulation of phospholipid biosynthetic process(GO:0071072) negative regulation of phospholipid metabolic process(GO:1903726)
0.0	0.1	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.2	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.2	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.2	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.3	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.3	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.8	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.2	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0071875	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.2	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0010665	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.1	GO:1903054	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.9	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.5	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.6	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.9	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.3	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.2	GO:0090177	establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.5	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.2	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0090037	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0035412	catenin import into nucleus(GO:0035411) regulation of catenin import into nucleus(GO:0035412)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:0031269	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.3	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.2	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.2	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.1	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	0.2	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.6	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.2	GO:0008347	glial cell migration(GO:0008347)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.0	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.2	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.1	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.3	GO:0002027	regulation of heart rate(GO:0002027)
0.0	0.0	GO:0014824	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0	0.1	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.0	GO:0002713	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.2	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.3	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.2	GO:0061515	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.1	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.2	GO:0046697	decidualization(GO:0046697)
0.0	0.1	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.0	GO:1904747	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.0	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.0	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.2	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.2	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.2	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.3	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.2	GO:1901983	regulation of histone acetylation(GO:0035065) regulation of protein acetylation(GO:1901983) regulation of peptidyl-lysine acetylation(GO:2000756)
0.0	0.0	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.0	GO:0060976	coronary vasculature development(GO:0060976)
0.0	0.0	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.2	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.2	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.1	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.0	0.0	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0048840	otolith development(GO:0048840)
0.0	0.1	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.2	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.2	GO:0007128	meiotic prophase I(GO:0007128)
0.0	0.0	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.1	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.0	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.0	GO:0021591	ventricular system development(GO:0021591)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.3	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0002076	osteoblast development(GO:0002076)
0.0	0.0	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.0	GO:0044557	relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0	0.0	GO:0048752	semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0	0.0	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	1.4	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.0	GO:0060068	vagina development(GO:0060068)
0.0	0.1	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.0	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:0070198	protein localization to chromosome, telomeric region(GO:0070198)
0.0	0.2	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:0072044	collecting duct development(GO:0072044)
0.0	0.0	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.0	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.0	GO:0034393	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.0	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.0	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.0	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.2	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0036296	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.0	GO:0008218	bioluminescence(GO:0008218)
0.0	0.0	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.8	GO:0001527	microfibril(GO:0001527)
0.1	0.4	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.8	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.5	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.5	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.2	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.2	GO:0043205	fibril(GO:0043205)
0.1	0.2	GO:0070852	cell body fiber(GO:0070852)
0.1	0.4	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.1	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.2	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.3	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0070938	contractile ring(GO:0070938)
0.0	0.1	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.3	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.4	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0010369	chromocenter(GO:0010369)
0.0	0.0	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.6	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.3	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.1	GO:0036126	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.3	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.4	GO:0005811	lipid particle(GO:0005811)
0.0	4.6	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.4	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	1.2	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.0	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.3	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.4	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.7	GO:0030426	growth cone(GO:0030426)
0.0	0.2	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.0	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.4	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.0	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.5	GO:0005903	brush border(GO:0005903)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.9	GO:0030016	myofibril(GO:0030016)
0.0	0.0	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2	1.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0016151	nickel cation binding(GO:0016151)
0.1	0.3	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.5	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.4	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	0.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.5	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.5	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.2	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.3	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.3	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1	0.6	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.9	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.8	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.2	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.5	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.4	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.2	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.2	GO:0043559	insulin binding(GO:0043559)
0.0	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.3	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.2	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.2	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	1.2	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0002060	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	0.3	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.7	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	1.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.4	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0004936	alpha-adrenergic receptor activity(GO:0004936) alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.1	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.0	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0016715	dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	2.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.3	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.6	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.3	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.0	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.2	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.0	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.2	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.0	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.3	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.2	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.4	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.0	0.1	GO:0008252	nucleotidase activity(GO:0008252)
0.0	0.0	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.0	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.0	GO:0004556	alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.0	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.0	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.0	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
1.7	NABA COLLAGENS	Genes encoding collagen proteins
0.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.7	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.6	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.4	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.5	PID PLK1 PATHWAY	PLK1 signaling events
0.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.6	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.3	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.5	PID AURORA B PATHWAY	Aurora B signaling
0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
2.4	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
2.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	0.8	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.5	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	2.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.0	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.0	0.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME HIV LIFE CYCLE	Genes involved in HIV Life Cycle
0.0	0.4	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.0	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle