Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PAX4

Z-value: 2.27

Motif logo

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Transcription factors associated with PAX4

Gene Symbol Gene ID Gene Info
ENSG00000106331.10 PAX4

Activity of the PAX4 motif across conditions

Conditions sorted by the z-value of the PAX4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_136873940_136874440 1.80 CXCR4
chemokine (C-X-C motif) receptor 4
377
0.92
chr1_234462239_234462527 1.67 ENSG00000264377
.
20170
0.13
chrX_118820590_118820815 1.67 SEPT6
septin 6
6090
0.19
chr12_6555099_6555250 1.57 CD27
CD27 molecule
1141
0.3
chrY_1605029_1605190 1.55 NA
NA
> 106
NA
chrX_1655035_1655190 1.52 P2RY8
purinergic receptor P2Y, G-protein coupled, 8
888
0.64
chr1_9713063_9713437 1.52 C1orf200
chromosome 1 open reading frame 200
1394
0.31
chr6_25041553_25042305 1.50 RP3-425P12.5

138
0.72
chr6_24934206_24934437 1.46 FAM65B
family with sequence similarity 65, member B
1867
0.41
chr10_6626003_6626633 1.46 PRKCQ
protein kinase C, theta
4055
0.36
chr12_57870819_57871184 1.35 ARHGAP9
Rho GTPase activating protein 9
566
0.53
chr5_156609052_156609245 1.35 ITK
IL2-inducible T-cell kinase
1311
0.34
chr14_22964398_22964682 1.33 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
8369
0.1
chr10_70847938_70848765 1.26 SRGN
serglycin
477
0.82
chr19_55765035_55765186 1.24 PPP6R1
protein phosphatase 6, regulatory subunit 1
2027
0.15
chr3_16328514_16328778 1.23 OXNAD1
oxidoreductase NAD-binding domain containing 1
17898
0.15
chr9_102972035_102972186 1.22 ENSG00000239908
.
107269
0.06
chr20_47439188_47439680 1.21 PREX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
4986
0.3
chr2_112177530_112177803 1.19 ENSG00000266139
.
98998
0.09
chr10_63661612_63662019 1.15 ARID5B
AT rich interactive domain 5B (MRF1-like)
756
0.74
chr1_39681454_39681741 1.15 RP11-416A14.1

9413
0.17
chr17_3866518_3867344 1.13 ATP2A3
ATPase, Ca++ transporting, ubiquitous
654
0.71
chr10_71332813_71333013 1.12 NEUROG3
neurogenin 3
81
0.97
chr8_134512242_134512393 1.12 ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
691
0.81
chr8_8705911_8706062 1.12 MFHAS1
malignant fibrous histiocytoma amplified sequence 1
45169
0.14
chr9_136005858_136006016 1.11 RALGDS
ral guanine nucleotide dissociation stimulator
567
0.69
chr8_21341401_21341552 1.11 ENSG00000266713
.
10063
0.28
chr22_29208131_29208282 1.09 CTA-292E10.8

2696
0.2
chr8_21770420_21771232 1.09 DOK2
docking protein 2, 56kDa
348
0.88
chr11_73692681_73692970 1.08 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
842
0.53
chr2_223290029_223290265 1.07 SGPP2
sphingosine-1-phosphate phosphatase 2
911
0.61
chr20_56194431_56194643 1.04 ZBP1
Z-DNA binding protein 1
913
0.65
chr17_1469834_1470011 1.02 PITPNA
phosphatidylinositol transfer protein, alpha
3812
0.15
chr5_110562007_110562166 1.01 CAMK4
calcium/calmodulin-dependent protein kinase IV
2302
0.35
chr1_244997563_244997714 1.01 COX20
COX20 cytochrome C oxidase assembly factor
986
0.55
chr13_99953854_99954138 0.99 GPR183
G protein-coupled receptor 183
5663
0.22
chr1_24831599_24831750 0.98 RCAN3
RCAN family member 3
2287
0.27
chr2_74198290_74198479 0.98 ENSG00000201876
.
3051
0.21
chr13_99890747_99890920 0.97 GPR18
G protein-coupled receptor 18
19795
0.17
chr22_31688704_31688855 0.96 PIK3IP1
phosphoinositide-3-kinase interacting protein 1
259
0.51
chr5_126188958_126189247 0.95 MARCH3
membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
64818
0.12
chr4_109087549_109087740 0.95 LEF1
lymphoid enhancer-binding factor 1
187
0.91
chr6_25086020_25086171 0.95 FAM65B
family with sequence similarity 65, member B
43857
0.13
chr22_17697616_17697767 0.94 CECR1
cat eye syndrome chromosome region, candidate 1
2575
0.29
chr3_142167005_142167365 0.94 XRN1
5'-3' exoribonuclease 1
281
0.89
chr4_40198272_40198423 0.94 RHOH
ras homolog family member H
180
0.96
chrX_71003427_71003880 0.94 ENSG00000221684
.
24348
0.23
chr1_111162215_111162656 0.93 KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
11661
0.19
chr19_42061527_42061721 0.92 CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
5738
0.18
chr6_135408926_135409077 0.92 HBS1L
HBS1-like (S. cerevisiae)
15193
0.21
chrX_12996930_12997081 0.92 TMSB4X
thymosin beta 4, X-linked
3228
0.3
chr6_149805654_149805958 0.92 ZC3H12D
zinc finger CCCH-type containing 12D
320
0.87
chr7_38340085_38340236 0.91 STARD3NL
STARD3 N-terminal like
122163
0.06
chr12_6736731_6736882 0.91 LPAR5
lysophosphatidic acid receptor 5
4009
0.1
chrX_70917705_70917856 0.89 ENSG00000221684
.
61525
0.11
chr14_97879855_97880006 0.89 ENSG00000240730
.
116580
0.07
chr19_3951230_3951381 0.89 DAPK3
death-associated protein kinase 3
9852
0.1
chr10_11206019_11206557 0.89 CELF2
CUGBP, Elav-like family member 2
705
0.72
chr7_26331698_26332123 0.87 SNX10
sorting nexin 10
225
0.95
chr11_108097659_108097810 0.85 ENSG00000206967
.
2597
0.21
chr17_43299697_43300109 0.85 CTD-2020K17.1

314
0.65
chr14_98100930_98101414 0.84 ENSG00000240730
.
104662
0.08
chrX_41195972_41196123 0.84 DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
2203
0.27
chr22_40781301_40781548 0.84 RP5-1042K10.10

2797
0.22
chr12_57999871_58000022 0.83 DTX3
deltex homolog 3 (Drosophila)
1156
0.25
chr16_1585013_1585440 0.83 TMEM204
transmembrane protein 204
1652
0.19
chr3_18477985_18478171 0.83 SATB1
SATB homeobox 1
1333
0.48
chr14_91882732_91883366 0.82 CCDC88C
coiled-coil domain containing 88C
641
0.78
chr15_60841858_60842044 0.82 CTD-2501E16.2

19779
0.18
chr12_32112702_32112978 0.81 KIAA1551
KIAA1551
487
0.85
chr6_108057983_108058134 0.81 SCML4
sex comb on midleg-like 4 (Drosophila)
4459
0.33
chr8_82044610_82044770 0.80 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
20387
0.26
chr12_92899150_92899489 0.79 ENSG00000238865
.
39444
0.17
chr8_111604369_111604520 0.78 KCNV1
potassium channel, subfamily V, member 1
616368
0.0
chr1_23928848_23928999 0.78 MDS2
myelodysplastic syndrome 2 translocation associated
24901
0.15
chr16_82125761_82125912 0.78 ENSG00000263636
.
18822
0.16
chr5_39214141_39214292 0.78 FYB
FYN binding protein
5449
0.31
chr8_74205022_74205806 0.77 RPL7
ribosomal protein L7
163
0.94
chr11_113945039_113945190 0.77 ENSG00000221112
.
12537
0.2
chr2_69005617_69005768 0.77 ARHGAP25
Rho GTPase activating protein 25
3620
0.29
chr1_8455637_8455851 0.76 RERE
arginine-glutamic acid dipeptide (RE) repeats
27982
0.15
chr7_98528304_98528455 0.76 TRRAP
transformation/transcription domain-associated protein
30076
0.15
chrX_11782139_11782290 0.76 MSL3
male-specific lethal 3 homolog (Drosophila)
4467
0.34
chr17_31830262_31830413 0.76 RP11-31I22.1

30442
0.17
chr18_2970989_2971515 0.76 RP11-737O24.1

4236
0.18
chr5_56115131_56115475 0.75 MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
3902
0.23
chr19_17957141_17957427 0.75 JAK3
Janus kinase 3
1542
0.26
chr18_3013543_3013794 0.75 LPIN2
lipin 2
355
0.86
chr14_81940547_81940744 0.74 STON2
stonin 2
37836
0.2
chr7_38312724_38312985 0.74 STARD3NL
STARD3 N-terminal like
94857
0.09
chr2_106363775_106364396 0.74 NCK2
NCK adaptor protein 2
1897
0.48
chr10_497094_497245 0.74 RP11-490E15.2

13668
0.2
chr11_128392558_128393039 0.74 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
593
0.77
chr6_2902429_2902783 0.73 SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
908
0.57
chr17_7790268_7790425 0.73 CHD3
chromodomain helicase DNA binding protein 3
1763
0.17
chr18_9404342_9404506 0.73 TWSG1
twisted gastrulation BMP signaling modulator 1
69576
0.08
chr12_25205029_25205380 0.73 LRMP
lymphoid-restricted membrane protein
1
0.98
chr2_8596387_8596552 0.73 AC011747.7

219427
0.02
chr22_37681278_37681429 0.73 CYTH4
cytohesin 4
2825
0.23
chr6_42749866_42750061 0.72 GLTSCR1L
GLTSCR1-like
198
0.94
chr18_63017285_63017436 0.72 CDH7
cadherin 7, type 2
400128
0.01
chr10_6628250_6628432 0.72 PRKCQ
protein kinase C, theta
6078
0.33
chr15_75162839_75163161 0.72 SCAMP2
secretory carrier membrane protein 2
2381
0.17
chr10_134358411_134358615 0.72 INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
6870
0.23
chr13_99856743_99857004 0.72 ENSG00000201793
.
1089
0.5
chr15_38852692_38852843 0.72 RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
287
0.91
chr20_57266602_57266883 0.71 NPEPL1
aminopeptidase-like 1
927
0.53
chr17_38478045_38478318 0.71 RARA
retinoic acid receptor, alpha
3644
0.15
chr2_62426916_62427067 0.71 B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
3743
0.21
chr15_69110570_69110988 0.71 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
2446
0.33
chr2_99351088_99351239 0.71 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
3574
0.28
chr10_8102231_8102679 0.71 GATA3
GATA binding protein 3
5686
0.34
chr9_14993938_14994089 0.71 RP11-54D18.3

54046
0.15
chr5_131801917_131802250 0.70 ENSG00000202533
.
1756
0.26
chr10_121356767_121357010 0.70 TIAL1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
347
0.9
chr5_55287497_55287648 0.70 IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
3220
0.19
chr10_6964732_6964883 0.70 PRKCQ
protein kinase C, theta
342544
0.01
chr3_71542168_71542650 0.70 ENSG00000221264
.
48831
0.15
chr9_100667597_100668036 0.70 C9orf156
chromosome 9 open reading frame 156
6937
0.17
chr4_147442457_147442985 0.70 SLC10A7
solute carrier family 10, member 7
148
0.97
chr6_109196078_109196273 0.70 ARMC2
armadillo repeat containing 2
5994
0.26
chr7_38272697_38272848 0.70 STARD3NL
STARD3 N-terminal like
54775
0.17
chr12_8124392_8124972 0.69 ENSG00000206636
.
4173
0.19
chr2_37763311_37763491 0.69 AC006369.2

63878
0.12
chr20_43599328_43599508 0.69 STK4
serine/threonine kinase 4
4251
0.17
chr12_104871725_104872091 0.69 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
21129
0.25
chr11_63974616_63975431 0.69 FERMT3
fermitin family member 3
266
0.78
chr20_43607716_43607876 0.69 STK4
serine/threonine kinase 4
12629
0.14
chr3_10546922_10547285 0.69 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
165
0.96
chr4_109093413_109093782 0.69 ENSG00000232021
.
258
0.93
chr1_47696290_47696441 0.69 TAL1
T-cell acute lymphocytic leukemia 1
922
0.51
chr4_37893272_37893641 0.68 TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
736
0.75
chrX_12996058_12996426 0.68 TMSB4X
thymosin beta 4, X-linked
2465
0.34
chr3_151914442_151914993 0.68 MBNL1
muscleblind-like splicing regulator 1
71112
0.11
chr21_42734513_42734686 0.68 MX2
myxovirus (influenza virus) resistance 2 (mouse)
665
0.73
chr1_154927981_154928289 0.67 PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
445
0.62
chr7_139333479_139333739 0.67 HIPK2
homeodomain interacting protein kinase 2
88232
0.08
chr17_7788638_7788948 0.67 LSMD1
LSM domain containing 1
266
0.71
chr16_87900894_87901428 0.67 SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
1933
0.31
chr5_95153586_95154314 0.67 GLRX
glutaredoxin (thioltransferase)
4465
0.17
chr8_28205788_28206519 0.67 ZNF395
zinc finger protein 395
2930
0.21
chr3_194406325_194406496 0.66 FAM43A
family with sequence similarity 43, member A
212
0.92
chr9_100001031_100001472 0.66 CCDC180
coiled-coil domain containing 180
472
0.86
chr21_15898945_15899096 0.66 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
19642
0.23
chr14_99735608_99735969 0.66 BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
1777
0.38
chr4_39031800_39031951 0.66 TMEM156
transmembrane protein 156
2166
0.33
chr2_47537091_47537242 0.66 EPCAM
epithelial cell adhesion molecule
35131
0.15
chrX_96221078_96221229 0.66 RPA4
replication protein A4, 30kDa
82246
0.11
chr12_104859017_104859249 0.65 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
8354
0.28
chr6_30460368_30460519 0.65 HLA-E
major histocompatibility complex, class I, E
3199
0.18
chr12_16064321_16064901 0.65 DERA
deoxyribose-phosphate aldolase (putative)
314
0.91
chr22_17567910_17568443 0.65 IL17RA
interleukin 17 receptor A
2327
0.26
chr1_207263069_207263220 0.65 C4BPB
complement component 4 binding protein, beta
257
0.89
chr2_202128643_202128845 0.64 CASP8
caspase 8, apoptosis-related cysteine peptidase
2065
0.33
chr17_40400288_40400799 0.64 RP11-358B23.5

20062
0.1
chr6_31544266_31544562 0.64 TNF
tumor necrosis factor
1070
0.2
chr7_130632583_130632734 0.64 LINC-PINT
long intergenic non-protein coding RNA, p53 induced transcript
36210
0.19
chr20_57227549_57228042 0.63 STX16
syntaxin 16
732
0.63
chr19_14543678_14543986 0.63 PKN1
protein kinase N1
33
0.96
chr12_8113260_8113485 0.63 ENSG00000206636
.
15483
0.14
chr11_75473950_75474101 0.63 DGAT2
diacylglycerol O-acyltransferase 2
3468
0.13
chr11_117151480_117151734 0.63 BACE1
beta-site APP-cleaving enzyme 1
14594
0.13
chr12_122751324_122751484 0.63 VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
336
0.87
chr17_28049647_28049902 0.63 RP11-82O19.1

38347
0.1
chrX_108780083_108780293 0.63 NXT2
nuclear transport factor 2-like export factor 2
83
0.98
chr18_13273051_13273333 0.62 LDLRAD4
low density lipoprotein receptor class A domain containing 4
4910
0.22
chr9_276345_276496 0.62 DOCK8
dedicator of cytokinesis 8
3350
0.24
chrX_13751200_13751351 0.62 TRAPPC2
trafficking protein particle complex 2
1400
0.33
chr17_33390476_33390701 0.62 RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
171
0.91
chr10_63807388_63807623 0.62 ARID5B
AT rich interactive domain 5B (MRF1-like)
1465
0.53
chr4_57773435_57773624 0.61 REST
RE1-silencing transcription factor
546
0.78
chr1_113164228_113164419 0.61 ST7L
suppression of tumorigenicity 7 like
2283
0.19
chr22_39640769_39640990 0.61 PDGFB
platelet-derived growth factor beta polypeptide
123
0.95
chrX_135066962_135067478 0.61 SLC9A6
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
378
0.87
chr4_119143007_119143249 0.61 ENSG00000269893
.
57217
0.16
chr20_50114477_50114741 0.61 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
44649
0.16
chr9_119464059_119464210 0.60 TRIM32
tripartite motif containing 32
14512
0.22
chr15_31634841_31635126 0.60 KLF13
Kruppel-like factor 13
2847
0.4
chr16_81479371_81479642 0.60 CMIP
c-Maf inducing protein
731
0.75
chr13_78052035_78052755 0.60 SCEL
sciellin
57414
0.14
chr18_60986998_60987174 0.60 BCL2
B-cell CLL/lymphoma 2
67
0.97
chrX_64255707_64255858 0.60 ZC4H2
zinc finger, C4H2 domain containing
1189
0.66
chr20_48315879_48316030 0.60 B4GALT5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
14461
0.19
chr16_3926295_3926446 0.60 CREBBP
CREB binding protein
3751
0.27
chr7_139529212_139529811 0.60 TBXAS1
thromboxane A synthase 1 (platelet)
401
0.9
chr12_68569605_68569756 0.60 IFNG
interferon, gamma
16153
0.23
chr12_80321656_80321807 0.60 PPP1R12A
protein phosphatase 1, regulatory subunit 12A
6764
0.2
chr6_31322820_31322971 0.60 HLA-B
major histocompatibility complex, class I, B
2069
0.19
chr14_75989604_75989915 0.59 BATF
basic leucine zipper transcription factor, ATF-like
856
0.62
chrX_128911631_128911951 0.59 SASH3
SAM and SH3 domain containing 3
2169
0.32
chr16_83760457_83760608 0.59 RP11-298D21.2

550
0.74
chr3_141249287_141249763 0.59 RASA2-IT1
RASA2 intronic transcript 1 (non-protein coding)
5550
0.26
chr4_140586980_140587576 0.59 MGST2
microsomal glutathione S-transferase 2
289
0.91
chr13_31312055_31312206 0.59 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
2485
0.4
chr1_169871916_169872111 0.59 SCYL3
SCY1-like 3 (S. cerevisiae)
8605
0.2
chr11_128798580_128798731 0.59 TP53AIP1
tumor protein p53 regulated apoptosis inducing protein 1
9058
0.16
chr13_43149529_43149680 0.59 TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
1244
0.64
chr7_130792062_130792405 0.58 LINC-PINT
long intergenic non-protein coding RNA, p53 induced transcript
444
0.83
chr5_80303307_80303458 0.58 CTC-459I6.1

46656
0.15
chr1_27754989_27755560 0.58 GPR3
G protein-coupled receptor 3
36126
0.11

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PAX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 0.6 GO:0002326 B cell lineage commitment(GO:0002326)
0.5 1.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.3 1.3 GO:0010761 fibroblast migration(GO:0010761)
0.3 0.9 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.3 1.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.3 0.8 GO:0072224 metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.2 0.7 GO:0033622 integrin activation(GO:0033622)
0.2 0.8 GO:0071025 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.2 0.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.2 1.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 0.6 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.8 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.2 1.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 0.5 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.2 0.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 2.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.7 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.2 0.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 0.3 GO:0006154 adenosine catabolic process(GO:0006154)
0.1 0.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.9 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 0.3 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.3 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 0.3 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.4 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.6 GO:0042447 hormone catabolic process(GO:0042447)
0.1 0.5 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.1 0.2 GO:0045588 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.1 0.6 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.1 0.3 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.4 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1 0.2 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1 0.3 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1 0.5 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 1.0 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.7 GO:0002063 chondrocyte development(GO:0002063)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 0.4 GO:0015911 plasma membrane long-chain fatty acid transport(GO:0015911)
0.1 0.7 GO:0046885 regulation of hormone biosynthetic process(GO:0046885)
0.1 0.3 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.4 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.9 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 0.2 GO:0018216 peptidyl-arginine methylation(GO:0018216) peptidyl-arginine N-methylation(GO:0035246)
0.1 0.3 GO:0001821 histamine secretion(GO:0001821)
0.1 0.3 GO:0007144 female meiosis I(GO:0007144)
0.1 0.1 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.1 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.3 GO:0042268 regulation of cytolysis(GO:0042268)
0.1 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.3 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.4 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.1 0.3 GO:0021702 cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.2 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.1 1.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.2 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.2 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.5 GO:0001782 B cell homeostasis(GO:0001782)
0.1 0.2 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1 0.3 GO:0022417 protein maturation by protein folding(GO:0022417)
0.1 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.6 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 1.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.1 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.1 0.2 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.1 0.5 GO:0006983 ER overload response(GO:0006983)
0.1 0.2 GO:0008049 male courtship behavior(GO:0008049)
0.1 0.2 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.7 GO:0000303 response to superoxide(GO:0000303)
0.1 0.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.2 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.1 0.3 GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.9 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 0.2 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1 0.5 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.3 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.2 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.1 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 0.6 GO:0042992 negative regulation of transcription factor import into nucleus(GO:0042992)
0.1 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.3 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.1 0.2 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 0.4 GO:0042119 neutrophil activation(GO:0042119)
0.1 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.1 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.3 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.8 GO:0006906 vesicle fusion(GO:0006906)
0.1 1.0 GO:0007032 endosome organization(GO:0007032)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.1 GO:0045064 T-helper 2 cell differentiation(GO:0045064) regulation of T-helper 2 cell differentiation(GO:0045628)
0.1 0.2 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 1.0 GO:0016574 histone ubiquitination(GO:0016574)
0.1 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.2 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 0.2 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.1 GO:0043555 regulation of translation in response to stress(GO:0043555) regulation of translational initiation in response to stress(GO:0043558)
0.1 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.6 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.6 GO:0031648 protein destabilization(GO:0031648)
0.1 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.2 GO:1902808 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.2 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.2 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.0 1.0 GO:0048278 vesicle docking(GO:0048278)
0.0 1.2 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.4 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.5 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.1 GO:0006907 pinocytosis(GO:0006907)
0.0 0.5 GO:0010921 regulation of phosphatase activity(GO:0010921) regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.3 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.3 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.2 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.3 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0 0.2 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.0 GO:0014742 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.2 GO:1903077 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0019884 NK T cell differentiation(GO:0001865) antigen processing and presentation of exogenous antigen(GO:0019884) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.2 GO:0033235 regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152) kidney smooth muscle tissue development(GO:0072194)
0.0 0.4 GO:0015879 amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.0 GO:0052166 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308) positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0015791 polyol transport(GO:0015791)
0.0 0.0 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.6 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.4 GO:0045576 mast cell activation(GO:0045576)
0.0 0.0 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.2 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0090232 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0060456 positive regulation of digestive system process(GO:0060456)
0.0 0.1 GO:0034405 response to fluid shear stress(GO:0034405)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.3 GO:1902591 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114) single-organism membrane budding(GO:1902591)
0.0 0.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.3 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.0 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0 0.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 2.2 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.0 GO:0002676 regulation of chronic inflammatory response(GO:0002676)
0.0 0.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0072202 cell differentiation involved in metanephros development(GO:0072202)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.4 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.4 GO:0032608 interferon-beta production(GO:0032608)
0.0 0.3 GO:0001975 response to amphetamine(GO:0001975)
0.0 0.1 GO:0072666 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 2.6 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 2.0 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0043954 cellular component maintenance(GO:0043954)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 6.7 GO:0016568 chromatin modification(GO:0016568)
0.0 0.0 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0051882 mitochondrial depolarization(GO:0051882)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.5 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.4 GO:0006885 regulation of pH(GO:0006885)
0.0 0.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.0 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.0 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 1.3 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0046629 gamma-delta T cell activation(GO:0046629)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.0 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.0 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 1.2 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.1 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.4 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.0 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.5 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0016241 regulation of macroautophagy(GO:0016241)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.3 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.7 GO:0006818 hydrogen transport(GO:0006818)
0.0 0.4 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.0 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0022601 menstrual cycle phase(GO:0022601)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0045923 positive regulation of fatty acid metabolic process(GO:0045923)
0.0 0.4 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.0 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.8 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.0 0.0 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.2 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.8 GO:0000236 mitotic prometaphase(GO:0000236)
0.0 0.0 GO:0002688 regulation of leukocyte chemotaxis(GO:0002688)
0.0 0.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.0 GO:2000189 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.9 GO:0050657 nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.0 0.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.0 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 1.1 GO:0006401 RNA catabolic process(GO:0006401)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0035601 protein deacetylation(GO:0006476) protein deacylation(GO:0035601) macromolecule deacylation(GO:0098732)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.8 GO:0034340 response to type I interferon(GO:0034340)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.3 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.0 GO:0052031 modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.0 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:2000406 T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.0 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.1 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.0 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.3 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.0 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.2 GO:0033574 response to testosterone(GO:0033574)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0050702 interleukin-1 beta secretion(GO:0050702)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.0 GO:0043441 acetoacetic acid biosynthetic process(GO:0043441)
0.0 0.2 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0051299 centrosome separation(GO:0051299)
0.0 3.3 GO:0006397 mRNA processing(GO:0006397)
0.0 0.1 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.0 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.1 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.0 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.0 GO:0031123 RNA 3'-end processing(GO:0031123)
0.0 0.2 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.0 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.0 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.0 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 0.0 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.4 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.2 GO:0002687 positive regulation of leukocyte migration(GO:0002687)
0.0 0.0 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.0 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 1.1 GO:0050900 leukocyte migration(GO:0050900)
0.0 0.0 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:0031333 negative regulation of protein complex assembly(GO:0031333)
0.0 0.0 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.0 GO:0061054 dermatome development(GO:0061054)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.1 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 0.0 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.0 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0048821 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.0 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0044743 intracellular protein transmembrane import(GO:0044743)
0.0 0.1 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.0 GO:0032490 detection of molecule of bacterial origin(GO:0032490)
0.0 0.0 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.5 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.1 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.2 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.1 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.7 GO:0006334 nucleosome assembly(GO:0006334) chromatin assembly(GO:0031497)
0.0 0.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.0 GO:2000647 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178) negative regulation of stem cell proliferation(GO:2000647)
0.0 0.1 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.1 GO:0006862 nucleotide transport(GO:0006862)
0.0 0.1 GO:0090317 negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of intracellular protein transport(GO:0090317)
0.0 0.0 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0006388 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0001824 blastocyst development(GO:0001824)
0.0 0.0 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.0 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.0 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0045008 depyrimidination(GO:0045008)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.0 GO:0071732 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.1 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
0.0 0.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0042629 mast cell granule(GO:0042629)
0.3 1.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 1.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.8 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.4 GO:0072487 MSL complex(GO:0072487)
0.1 0.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.4 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.4 GO:0005827 polar microtubule(GO:0005827)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.2 GO:0005844 polysome(GO:0005844)
0.1 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.2 GO:0032449 CBM complex(GO:0032449)
0.1 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.2 GO:0031211 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.6 GO:0030897 HOPS complex(GO:0030897)
0.1 0.2 GO:0071942 XPC complex(GO:0071942)
0.1 0.3 GO:0001741 XY body(GO:0001741)
0.1 0.2 GO:0016589 NURF complex(GO:0016589)
0.1 0.3 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.1 0.6 GO:0071564 npBAF complex(GO:0071564)
0.1 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.0 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 2.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.0 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 2.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.4 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.0 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 1.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0043656 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.0 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0005770 late endosome(GO:0005770)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.1 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0000123 histone acetyltransferase complex(GO:0000123) protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 8.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0034708 methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:1902562 H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0 0.3 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.0 GO:0071547 piP-body(GO:0071547)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.0 GO:0005883 neurofilament(GO:0005883)
0.0 0.5 GO:0005840 ribosome(GO:0005840)
0.0 9.6 GO:0005730 nucleolus(GO:0005730)
0.0 1.8 GO:0005774 vacuolar membrane(GO:0005774)
0.0 0.4 GO:0000502 proteasome complex(GO:0000502)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 10.4 GO:0005739 mitochondrion(GO:0005739)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.4 1.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4 1.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 0.9 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 0.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 2.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 0.6 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 0.5 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.2 2.0 GO:0004697 protein kinase C activity(GO:0004697)
0.2 2.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.6 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 1.3 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.4 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.7 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.4 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.7 GO:0051400 BH domain binding(GO:0051400)
0.1 0.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.3 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.3 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.1 GO:0009374 biotin binding(GO:0009374)
0.1 2.1 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.8 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.1 0.4 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.6 GO:0008494 translation activator activity(GO:0008494)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.9 GO:0019843 rRNA binding(GO:0019843)
0.1 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.3 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 1.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.8 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.2 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.1 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.7 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.1 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 1.0 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.1 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.3 GO:0031013 troponin I binding(GO:0031013)
0.1 0.5 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 1.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.2 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 1.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.3 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 3.9 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 1.0 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.4 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 3.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0032451 demethylase activity(GO:0032451)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 2.1 GO:0003682 chromatin binding(GO:0003682)
0.0 0.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.4 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.0 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.3 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.0 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.9 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.3 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.0 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.3 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0019201 nucleotide kinase activity(GO:0019201)
0.0 0.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0051184 cofactor transporter activity(GO:0051184)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 2.0 GO:0016563 obsolete transcription activator activity(GO:0016563)
0.0 0.0 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 3.0 GO:0016874 ligase activity(GO:0016874)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 1.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 5.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 0.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.4 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 0.3 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 1.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.5 PID IL27 PATHWAY IL27-mediated signaling events
0.1 3.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 0.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 0.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.2 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 0.6 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 1.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 0.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 2.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 3.4 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.1 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.3 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.9 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.2 REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT Genes involved in The citric acid (TCA) cycle and respiratory electron transport
0.0 0.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.1 REACTOME M G1 TRANSITION Genes involved in M/G1 Transition
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL