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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for PAX6

Z-value: 2.26

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Transcription factors associated with PAX6

Gene Symbol	Gene ID	Gene Info
PAX6 Ensembl NCBI GeneCards UniProt	ENSG00000007372.16	paired box 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_31827177_31827328	PAX6	1217	0.495863	0.82	7.3e-03	Click!
chr11_31820977_31821140	PAX6	7411	0.209429	0.74	2.2e-02	Click!
chr11_31831142_31831293	PAX6	636	0.717792	0.73	2.6e-02	Click!
chr11_31819962_31820225	PAX6	8376	0.205760	0.65	5.9e-02	Click!
chr11_31892590_31892741	PAX6	53156	0.132864	0.60	8.5e-02	Click!

Activity of the PAX6 motif across conditions

Conditions sorted by the z-value of the PAX6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_163040363_163040678	1.84	RGS4	regulator of G-protein signaling 4	1314	0.56
chr9_13568681_13569117	1.19	MPDZ	multiple PDZ domain protein	289310	0.01
chr8_104197199_104197403	0.90	RP11-318M2.2		12933	0.14
chr5_83680091_83680703	0.85	CTD-2269F5.1		23	0.71
chr10_60235657_60235933	0.83	BICC1	bicaudal C homolog 1 (Drosophila)	37105	0.2
chr2_188417834_188418053	0.79	AC007319.1		933	0.47
chr13_96295623_96295774	0.77	DZIP1	DAZ interacting zinc finger protein 1	181	0.96
chr6_27516181_27516437	0.76	ENSG00000206671	.	47882	0.13
chr1_67000815_67001114	0.76	SGIP1	SH3-domain GRB2-like (endophilin) interacting protein 1	999	0.67
chr2_36924555_36924939	0.76	VIT	vitrin	727	0.75
chr12_46518814_46519037	0.70	SCAF11	SR-related CTD-associated factor 11	133022	0.05
chr6_21310055_21310473	0.68	SOX4	SRY (sex determining region Y)-box 4	283708	0.01
chr4_74809740_74810515	0.68	PF4	platelet factor 4	37714	0.11
chr1_172313169_172313650	0.67	ENSG00000252354	.	3874	0.23
chr3_157250943_157251353	0.67	VEPH1	ventricular zone expressed PH domain-containing 1	247	0.94
chr18_53068422_53068903	0.66	TCF4	transcription factor 4	96	0.98
chr4_39522963_39523180	0.66	UGDH	UDP-glucose 6-dehydrogenase	5106	0.17
chr4_55093553_55093862	0.66	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	1557	0.51
chr6_138976372_138976635	0.65	RP11-390P2.4		37182	0.17
chr2_66664825_66665240	0.65	MEIS1	Meis homeobox 1	93	0.96
chr12_16500618_16501134	0.64	MGST1	microsomal glutathione S-transferase 1	145	0.97
chr1_221892176_221892506	0.64	DUSP10	dual specificity phosphatase 10	18461	0.29
chr8_32506055_32506353	0.61	NRG1	neuregulin 1	847	0.76
chr2_218806750_218806920	0.59	TNS1	tensin 1	1958	0.38
chr3_168759646_168760009	0.59	MECOM	MDS1 and EVI1 complex locus	85995	0.11
chr2_217237286_217237473	0.59	MARCH4	membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase	629	0.69
chr6_53934757_53935103	0.59	MLIP-AS1	MLIP antisense RNA 1	9594	0.22
chr18_56029142_56029527	0.58	RP11-845C23.2		9464	0.19
chr1_240264021_240264305	0.57	FMN2	formin 2	8983	0.26
chr3_104078695_104079148	0.57	ENSG00000265076	.	305281	0.01
chr18_32073627_32073820	0.57	DTNA	dystrobrevin, alpha	144	0.98
chr7_43288991_43289248	0.56	AC004692.4		252	0.93
chr12_66221542_66221865	0.56	HMGA2	high mobility group AT-hook 2	2800	0.29
chr3_151791319_151791512	0.56	RP11-454C18.2		145452	0.04
chr1_179111876_179112093	0.56	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	195	0.95
chr9_14096707_14097036	0.55	NFIB	nuclear factor I/B	83920	0.11
chr1_110933695_110934011	0.55	SLC16A4	solute carrier family 16, member 4	149	0.93
chr7_134465998_134466492	0.55	CALD1	caldesmon 1	1816	0.49
chr8_38153609_38153832	0.55	RP11-513D5.5		20314	0.11
chr2_238320302_238320453	0.55	COL6A3	collagen, type VI, alpha 3	2414	0.31
chr3_173302672_173303490	0.54	NLGN1	neuroligin 1	371	0.93
chr4_4784046_4784388	0.54	MSX1	msh homeobox 1	77176	0.11
chr13_67708586_67709053	0.54	PCDH9	protocadherin 9	93753	0.09
chr21_17568279_17568430	0.53	ENSG00000201025	.	88735	0.1
chr18_60092781_60092970	0.52	RP11-640A1.3		47512	0.14
chr4_186696107_186696537	0.52	SORBS2	sorbin and SH3 domain containing 2	108	0.98
chr11_68780147_68780456	0.51	RP11-554A11.6		402	0.45
chr16_86774936_86775161	0.51	FOXL1	forkhead box L1	162933	0.03
chr8_104155486_104155705	0.51	C8orf56	chromosome 8 open reading frame 56	1892	0.22
chr17_67055930_67056124	0.51	ABCA9	ATP-binding cassette, sub-family A (ABC1), member 9	1020	0.57
chr6_148593126_148593282	0.51	SASH1	SAM and SH3 domain containing 1	236	0.93
chr13_33858654_33859881	0.51	STARD13	StAR-related lipid transfer (START) domain containing 13	625	0.76
chr4_81192022_81192173	0.51	FGF5	fibroblast growth factor 5	4304	0.29
chr9_79502750_79503010	0.51	PRUNE2	prune homolog 2 (Drosophila)	18121	0.27
chr3_99357829_99358140	0.50	COL8A1	collagen, type VIII, alpha 1	530	0.85
chr2_159788512_159788928	0.50	ENSG00000222300	.	3777	0.25
chr15_63339134_63339580	0.50	TPM1	tropomyosin 1 (alpha)	1208	0.41
chr8_131960988_131961496	0.50	RP11-737F9.1		13587	0.24
chr4_148947373_148947715	0.50	RP11-76G10.1		120078	0.06
chr4_15471787_15471987	0.49	CC2D2A	coiled-coil and C2 domain containing 2A	250	0.93
chr17_42906288_42907233	0.49	GJC1	gap junction protein, gamma 1, 45kDa	302	0.85
chr13_24146066_24146217	0.49	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1338	0.59
chr10_33620428_33620906	0.49	NRP1	neuropilin 1	2643	0.37
chr14_93736061_93736314	0.49	BTBD7	BTB (POZ) domain containing 7	24308	0.15
chr1_247506079_247506341	0.49	ZNF496	zinc finger protein 496	11165	0.18
chr15_79854706_79854896	0.49	KIAA1024	KIAA1024	129943	0.05
chr10_31435945_31436159	0.48	ENSG00000263578	.	81076	0.1
chr2_65585991_65586247	0.48	SPRED2	sprouty-related, EVH1 domain containing 2	7665	0.24
chr8_38585652_38586394	0.48	TACC1	transforming, acidic coiled-coil containing protein 1	82	0.97
chr15_49098304_49098486	0.48	CEP152	centrosomal protein 152kDa	4396	0.19
chr1_179111271_179111703	0.48	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	692	0.72
chr8_67468064_67468215	0.48	ENSG00000206949	.	54593	0.1
chr5_37810419_37810701	0.48	ENSG00000238335	.	8393	0.24
chr1_236147536_236147733	0.48	ENSG00000206803	.	68919	0.09
chr1_163044997_163045289	0.48	RGS4	regulator of G-protein signaling 4	3207	0.34
chr10_25007260_25007463	0.48	ARHGAP21	Rho GTPase activating protein 21	3434	0.35
chr12_46949518_46949939	0.48	SLC38A2	solute carrier family 38, member 2	183078	0.03
chrX_23686647_23686860	0.47	PRDX4	peroxiredoxin 4	1085	0.58
chr8_42063953_42065062	0.47	PLAT	plasminogen activator, tissue	576	0.71
chr4_119094947_119095286	0.47	ENSG00000269893	.	105229	0.08
chr7_42355171_42355392	0.47	GLI3	GLI family zinc finger 3	78623	0.12
chr7_93552513_93552820	0.47	GNG11	guanine nucleotide binding protein (G protein), gamma 11	1655	0.33
chr7_138348504_138348889	0.47	SVOPL	SVOP-like	273	0.93
chr4_55097787_55097981	0.47	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	1395	0.55
chr1_231002708_231002859	0.47	C1orf198	chromosome 1 open reading frame 198	1616	0.28
chr4_74734701_74735215	0.47	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	163	0.94
chr15_30922047_30922198	0.47	ARHGAP11B	Rho GTPase activating protein 11B	3243	0.11
chr18_52357258_52357685	0.47	RAB27B	RAB27B, member RAS oncogene family	27620	0.24
chr9_35516264_35516818	0.47	RUSC2	RUN and SH3 domain containing 2	22088	0.14
chr13_98630173_98630324	0.47	IPO5	importin 5	1031	0.66
chr4_181928076_181928259	0.46	ENSG00000251742	.	828094	0.0
chr6_155005040_155005564	0.46	SCAF8	SR-related CTD-associated factor 8	49157	0.17
chr4_113773971_113774122	0.46	RP11-119H12.6		29440	0.18
chr5_89317042_89317197	0.46	ENSG00000264342	.	4582	0.37
chr7_19154419_19154620	0.46	AC003986.6		2422	0.22
chr6_80254303_80254623	0.46	LCA5	Leber congenital amaurosis 5	7288	0.3
chr4_86853777_86853998	0.46	ARHGAP24	Rho GTPase activating protein 24	2461	0.32
chr2_39662878_39663172	0.46	AC007246.3		753	0.54
chr4_85888141_85888634	0.46	WDFY3	WD repeat and FYVE domain containing 3	843	0.73
chr7_147097413_147097615	0.46	ENSG00000221442	.	22301	0.28
chrX_114828631_114828846	0.46	PLS3	plastin 3	873	0.64
chr18_25703623_25703892	0.46	CDH2	cadherin 2, type 1, N-cadherin (neuronal)	26564	0.27
chr6_144570442_144570614	0.45	UTRN	utrophin	36309	0.2
chr10_25008347_25008498	0.45	ARHGAP21	Rho GTPase activating protein 21	2373	0.41
chr15_63446474_63446661	0.45	RPS27L	ribosomal protein S27-like	2406	0.28
chr12_106530238_106530817	0.45	NUAK1	NUAK family, SNF1-like kinase, 1	3284	0.3
chrX_83756622_83756797	0.45	HDX	highly divergent homeobox	690	0.48
chr19_9473504_9474272	0.45	ZNF177	zinc finger protein 177	181	0.93
chr7_19145980_19146451	0.45	AC003986.6		5882	0.17
chr6_135679919_135680436	0.44	AHI1	Abelson helper integration site 1	52469	0.13
chr1_201425782_201426096	0.44	PHLDA3	pleckstrin homology-like domain, family A, member 3	12373	0.15
chr7_94004298_94004620	0.44	COL1A2	collagen, type I, alpha 2	19414	0.26
chr10_95274973_95275229	0.44	ENSG00000212396	.	4664	0.19
chr16_53244996_53245358	0.44	CHD9	chromodomain helicase DNA binding protein 9	2814	0.29
chr6_94494975_94495370	0.44	ENSG00000252249	.	93652	0.1
chr9_120497648_120497799	0.44	ENSG00000251847	.	3974	0.26
chr10_52191139_52191567	0.44	AC069547.2	Uncharacterized protein	38587	0.15
chr5_88178054_88178448	0.44	MEF2C	myocyte enhancer factor 2C	713	0.52
chr2_41837870_41838465	0.44	ENSG00000221372	.	14641	0.29
chr8_123801020_123801334	0.44	ZHX2	zinc fingers and homeoboxes 2	7544	0.22
chrX_33227749_33227900	0.44	DMD	dystrophin	1605	0.57
chr3_112354765_112355126	0.43	CCDC80	coiled-coil domain containing 80	1999	0.4
chr1_193304797_193304948	0.43	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	149088	0.04
chr13_113365888_113366065	0.43	ENSG00000264726	.	6252	0.2
chr13_93880393_93880808	0.43	GPC6	glypican 6	1505	0.58
chr6_64017987_64018177	0.43	LGSN	lengsin, lens protein with glutamine synthetase domain	11800	0.29
chr2_44518253_44518404	0.43	SLC3A1	solute carrier family 3 (amino acid transporter heavy chain), member 1	5694	0.21
chr6_169652381_169652976	0.43	THBS2	thrombospondin 2	432	0.89
chr5_57555667_57556212	0.43	ENSG00000238899	.	189924	0.03
chr8_6149062_6149390	0.43	RP11-115C21.2		114837	0.06
chr21_30673835_30674113	0.43	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	851	0.62
chr15_59622460_59622641	0.43	ENSG00000199512	.	11066	0.14
chr16_86619409_86619937	0.43	FOXL1	forkhead box L1	7558	0.18
chr16_69309884_69310035	0.43	RP11-343C2.11	Uncharacterized protein	23626	0.1
chr7_19155354_19155672	0.42	TWIST1	twist family bHLH transcription factor 1	1782	0.28
chr7_100773540_100774051	0.42	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	3416	0.13
chr7_94964422_94964573	0.42	PON1	paraoxonase 1	10478	0.21
chr1_227503732_227504041	0.42	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)	997	0.69
chr13_24007256_24007423	0.42	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)	502	0.88
chr2_133105502_133105810	0.42	ENSG00000252705	.	58775	0.12
chr2_198538241_198538478	0.42	RFTN2	raftlin family member 2	2360	0.29
chr5_22212541_22212718	0.42	CDH12	cadherin 12, type 2 (N-cadherin 2)	1230	0.59
chr10_128995077_128995475	0.41	FAM196A	family with sequence similarity 196, member A	854	0.75
chr7_14418809_14419008	0.41	ENSG00000252374	.	368520	0.01
chr12_125073530_125073715	0.41	NCOR2	nuclear receptor corepressor 2	21612	0.27
chr4_134068181_134068851	0.41	PCDH10	protocadherin 10	1954	0.52
chr18_8609852_8610932	0.41	RAB12	RAB12, member RAS oncogene family	949	0.6
chr3_55514769_55515136	0.41	WNT5A	wingless-type MMTV integration site family, member 5A	272	0.94
chr15_96869932_96870158	0.41	NR2F2-AS1	NR2F2 antisense RNA 1	205	0.86
chr6_74406883_74407034	0.41	RP11-553A21.3		1104	0.37
chr2_239758985_239759136	0.41	TWIST2	twist family bHLH transcription factor 2	2387	0.39
chr10_18294252_18294909	0.41	SLC39A12-AS1	SLC39A12 antisense RNA 1	1619	0.47
chr17_60905052_60905372	0.41	MARCH10	membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase	19507	0.23
chr15_64231749_64232239	0.40	RP11-111E14.1		11521	0.22
chr10_34827521_34827675	0.40	PARD3	par-3 family cell polarity regulator	111939	0.07
chr3_87035332_87035763	0.40	VGLL3	vestigial like 3 (Drosophila)	4305	0.37
chr14_56808787_56808938	0.40	TMEM260	transmembrane protein 260	146210	0.04
chr1_156540904_156541055	0.40	IQGAP3	IQ motif containing GTPase activating protein 3	1353	0.26
chr4_11652300_11652527	0.40	HS3ST1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	221024	0.02
chr11_7911988_7912218	0.40	ENSG00000252769	.	1277	0.37
chr4_16899723_16900066	0.40	LDB2	LIM domain binding 2	291	0.95
chr10_79730818_79731123	0.39	DLG5-AS1	DLG5 antisense RNA 1	43840	0.12
chr2_175831081_175831232	0.39	ENSG00000201425	.	11375	0.19
chr3_29324199_29324416	0.39	RBMS3	RNA binding motif, single stranded interacting protein 3	1200	0.55
chr22_46461260_46461448	0.39	RP6-109B7.4		4417	0.11
chr5_321961_322616	0.39	AHRR	aryl-hydrocarbon receptor repressor	397	0.84
chr1_9254295_9254446	0.39	H6PD	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	40464	0.12
chr12_32261770_32262117	0.39	RP11-843B15.2		1481	0.38
chr11_16813436_16813790	0.39	PLEKHA7	pleckstrin homology domain containing, family A member 7	20417	0.2
chr2_177501805_177501995	0.39	ENSG00000252027	.	27504	0.25
chr6_149354145_149354352	0.39	RP11-162J8.3		539	0.84
chr7_83822850_83823057	0.39	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	1264	0.65
chr2_159610172_159610621	0.39	AC005042.4		18882	0.21
chr10_33723534_33723685	0.39	NRP1	neuropilin 1	98419	0.08
chr11_101453394_101453891	0.38	TRPC6	transient receptor potential cation channel, subfamily C, member 6	592	0.84
chr8_120649956_120650241	0.38	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	922	0.68
chr5_39423074_39423254	0.38	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	1806	0.48
chr12_15490350_15490501	0.38	RERG	RAS-like, estrogen-regulated, growth inhibitor	11107	0.24
chr3_168959825_168960526	0.38	MECOM	MDS1 and EVI1 complex locus	26851	0.26
chr5_137475160_137475365	0.38	NME5	NME/NM23 family member 5	158	0.92
chr6_20438864_20439015	0.38	E2F3-IT1	E2F3 intronic transcript 1 (non-protein coding)	887	0.51
chr2_74691535_74692741	0.38	MOGS	mannosyl-oligosaccharide glucosidase	351	0.67
chr5_54456456_54456818	0.38	GPX8	glutathione peroxidase 8 (putative)	639	0.58
chr15_59599194_59599413	0.38	ENSG00000199512	.	34313	0.11
chr13_111922547_111922806	0.38	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	29109	0.2
chr5_91977319_91977616	0.38	ENSG00000221810	.	75753	0.13
chr1_230367637_230367834	0.38	RP5-956O18.2		36494	0.18
chr3_61833858_61834009	0.37	ENSG00000252420	.	109030	0.08
chr6_2789380_2789655	0.37	WRNIP1	Werner helicase interacting protein 1	20510	0.17
chr7_95239102_95239253	0.37	AC002451.3		69	0.98
chr7_94027821_94027972	0.37	COL1A2	collagen, type I, alpha 2	4023	0.33
chr16_89990965_89991193	0.37	TUBB3	Tubulin beta-3 chain	1305	0.26
chr12_45428919_45429070	0.37	RP11-478B9.1		15690	0.21
chr18_54046287_54046510	0.37	TXNL1	thioredoxin-like 1	235324	0.02
chr7_120380736_120380895	0.37	KCND2	potassium voltage-gated channel, Shal-related subfamily, member 2	83	0.98
chr18_43303934_43304085	0.37	SLC14A1	solute carrier family 14 (urea transporter), member 1 (Kidd blood group)	83	0.97
chr2_197143535_197143686	0.37	ENSG00000264627	.	10523	0.2
chr6_53935109_53935336	0.36	MLIP-AS1	MLIP antisense RNA 1	9302	0.22
chr14_100260916_100261174	0.36	EML1	echinoderm microtubule associated protein like 1	1273	0.55
chr9_134055367_134055573	0.36	NUP214	nucleoporin 214kDa	10038	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.2	0.7	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.2	0.9	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.4	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.2	0.9	GO:0070208	protein heterotrimerization(GO:0070208)
0.2	0.8	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.2	0.6	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.2	1.4	GO:0033327	Leydig cell differentiation(GO:0033327)
0.2	0.5	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.2	0.5	GO:0031223	auditory behavior(GO:0031223)
0.2	0.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.9	GO:0016264	gap junction assembly(GO:0016264)
0.1	0.5	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.1	0.9	GO:0060259	regulation of feeding behavior(GO:0060259)
0.1	0.4	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	1.0	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.9	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1	0.4	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.6	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.4	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.5	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.2	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.1	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
0.1	0.3	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.3	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.3	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.6	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1	0.4	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.3	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.4	GO:0033088	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.6	GO:0015840	urea transport(GO:0015840)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.4	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.4	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.1	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.6	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.2	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1	0.2	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.1	GO:0010996	response to auditory stimulus(GO:0010996)
0.1	0.5	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1	0.2	GO:0030202	heparin metabolic process(GO:0030202)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.2	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1	0.2	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.1	0.5	GO:0060039	pericardium development(GO:0060039)
0.1	0.4	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.2	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.1	0.8	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.1	0.1	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.1	0.5	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742) histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1	0.2	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	0.2	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.1	0.2	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.2	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	0.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.3	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.1	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.1	GO:0007412	axon target recognition(GO:0007412)
0.1	1.6	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.3	GO:0010107	potassium ion import(GO:0010107)
0.1	0.7	GO:0035329	hippo signaling(GO:0035329)
0.1	0.3	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.4	GO:0015871	choline transport(GO:0015871)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	0.1	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.1	0.2	GO:0030091	protein repair(GO:0030091)
0.1	0.1	GO:0060841	venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.1	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.1	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.8	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.4	GO:0046485	ether lipid metabolic process(GO:0046485)
0.1	0.3	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.1	0.2	GO:0048539	bone marrow development(GO:0048539)
0.1	0.1	GO:0060068	vagina development(GO:0060068)
0.1	0.3	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.1	0.2	GO:0016241	regulation of macroautophagy(GO:0016241)
0.1	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.2	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1	0.1	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.1	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.3	GO:0031641	regulation of myelination(GO:0031641)
0.1	0.1	GO:0090009	primitive streak formation(GO:0090009)
0.1	0.3	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.1	0.4	GO:0006228	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.1	0.2	GO:0021794	thalamus development(GO:0021794)
0.1	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.7	GO:0071453	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0	0.1	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0002604	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.1	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.4	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.0	GO:0090594	wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594) connective tissue replacement(GO:0097709)
0.0	0.3	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.2	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	0.2	GO:0001757	somite specification(GO:0001757)
0.0	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.8	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.3	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.2	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.6	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.2	GO:0060023	soft palate development(GO:0060023)
0.0	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:1904063	negative regulation of cation transmembrane transport(GO:1904063)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.7	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.2	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.0	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0072070	loop of Henle development(GO:0072070)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:1901374	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.1	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.1	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.2	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.1	GO:0033005	positive regulation of mast cell activation(GO:0033005)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.0	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.3	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.2	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0090036	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.1	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0034444	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.2	GO:0031000	response to caffeine(GO:0031000)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0031620	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.2	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.0	0.0	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.1	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	1.3	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.3	GO:0030325	adrenal gland development(GO:0030325)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.0	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0045683	negative regulation of epidermal cell differentiation(GO:0045605) negative regulation of epidermis development(GO:0045683)
0.0	0.1	GO:0060192	negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.0	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0	0.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.1	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.4	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0006991	response to sterol depletion(GO:0006991)
0.0	0.2	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.2	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.0	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.0	0.0	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.1	GO:0070091	glucagon secretion(GO:0070091)
0.0	0.0	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.2	GO:0001508	action potential(GO:0001508)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.1	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.2	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0048566	embryonic digestive tract development(GO:0048566)
0.0	0.2	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.3	GO:0042551	neuron maturation(GO:0042551)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0003211	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.1	GO:0060620	sterol import(GO:0035376) regulation of cholesterol import(GO:0060620) cholesterol import(GO:0070508) regulation of sterol import(GO:2000909)
0.0	0.1	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.7	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.0	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.1	GO:0010586	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0048485	sympathetic nervous system development(GO:0048485)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0008038	neuron recognition(GO:0008038)
0.0	0.1	GO:0060009	Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0	0.0	GO:0022601	menstrual cycle phase(GO:0022601)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.0	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.0	GO:0052556	positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0	0.1	GO:0043084	penile erection(GO:0043084)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.0	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.0	GO:0071267	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:0055023	positive regulation of cardiac muscle tissue growth(GO:0055023) positive regulation of cardiac muscle tissue development(GO:0055025) positive regulation of cardiac muscle cell proliferation(GO:0060045)
0.0	0.2	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	0.4	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.0	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.0	GO:0070295	renal water absorption(GO:0070295)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0061383	trabecula formation(GO:0060343) bone trabecula formation(GO:0060346) trabecula morphogenesis(GO:0061383) bone trabecula morphogenesis(GO:0061430)
0.0	0.0	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.0	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.0	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.0	GO:0060745	mammary gland branching involved in pregnancy(GO:0060745)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:0051299	centrosome separation(GO:0051299)
0.0	0.0	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.1	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.0	GO:0048854	brain morphogenesis(GO:0048854)
0.0	0.0	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:0035136	forelimb morphogenesis(GO:0035136)
0.0	0.2	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.0	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.1	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0060071	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.2	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.0	GO:0051310	metaphase plate congression(GO:0051310)
0.0	0.0	GO:0019730	antimicrobial humoral response(GO:0019730)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.0	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0050748	negative regulation of lipoprotein metabolic process(GO:0050748)
0.0	0.1	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.0	0.1	GO:0060123	regulation of growth hormone secretion(GO:0060123) positive regulation of growth hormone secretion(GO:0060124)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.4	GO:0071773	BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0	0.1	GO:0008347	glial cell migration(GO:0008347)
0.0	1.7	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.0	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.1	GO:0018126	protein hydroxylation(GO:0018126)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.0	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.0	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.2	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.1	GO:0007530	sex determination(GO:0007530)
0.0	0.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.0	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.0	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.0	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.0	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0007616	long-term memory(GO:0007616)
0.0	0.0	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.0	GO:0021554	optic nerve development(GO:0021554)
0.0	0.1	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.0	0.3	GO:0042303	molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0	0.0	GO:0003401	axis elongation(GO:0003401)
0.0	0.2	GO:0017157	regulation of exocytosis(GO:0017157)
0.0	0.0	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.3	GO:0001764	neuron migration(GO:0001764)
0.0	0.1	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.0	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.1	GO:1900077	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.0	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0098856	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0	0.2	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.2	GO:0007128	meiotic prophase I(GO:0007128)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.0	GO:1902170	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0	0.2	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.1	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0099518	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.0	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0006893	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	0.0	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.2	GO:0007098	centrosome cycle(GO:0007098)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.6	GO:0070852	cell body fiber(GO:0070852)
0.1	1.0	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.9	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.3	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.4	GO:0032059	bleb(GO:0032059)
0.1	0.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.9	GO:0098644	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) complex of collagen trimers(GO:0098644)
0.1	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.6	GO:0005916	fascia adherens(GO:0005916)
0.1	0.8	GO:0043034	costamere(GO:0043034)
0.1	0.8	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1	0.3	GO:0005915	zonula adherens(GO:0005915)
0.1	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.4	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.2	GO:0043657	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	0.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	0.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.4	GO:0008091	spectrin(GO:0008091)
0.0	0.4	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.4	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.4	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.4	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.3	GO:0043205	fibril(GO:0043205)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	2.1	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.4	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.5	GO:0005811	lipid particle(GO:0005811)
0.0	1.3	GO:0005604	basement membrane(GO:0005604)
0.0	0.7	GO:0034704	calcium channel complex(GO:0034704)
0.0	1.6	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	2.4	GO:0030016	myofibril(GO:0030016)
0.0	4.9	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.7	GO:0005884	actin filament(GO:0005884)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.3	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.0	GO:0044447	axoneme part(GO:0044447)
0.0	0.5	GO:0032155	cell division site(GO:0032153) cell division site part(GO:0032155)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.8	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.0	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.6	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.3	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.2	GO:0043195	terminal bouton(GO:0043195)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.0	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.0	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.6	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.6	GO:0005802	trans-Golgi network(GO:0005802)
0.0	1.7	GO:0045177	apical part of cell(GO:0045177)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0032421	stereocilium bundle(GO:0032421)
0.0	0.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.3	GO:0016459	myosin complex(GO:0016459)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3	0.8	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2	0.7	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	0.7	GO:0002162	dystroglycan binding(GO:0002162)
0.2	0.7	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.2	0.7	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.4	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.3	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.8	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.8	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.3	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.4	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.6	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.3	GO:0005113	patched binding(GO:0005113)
0.1	1.3	GO:0005523	tropomyosin binding(GO:0005523)
0.1	1.1	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	0.4	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.4	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.5	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.9	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.3	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.3	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.2	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.3	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.4	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.2	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.3	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	0.4	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.1	GO:0043559	insulin binding(GO:0043559)
0.1	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	0.5	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.6	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.2	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.1	0.4	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.3	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.8	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.2	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.4	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.4	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.2	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.9	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.2	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	1.4	GO:0005518	collagen binding(GO:0005518)
0.0	0.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.3	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.3	GO:0015926	glucosidase activity(GO:0015926)
0.0	0.5	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.3	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.5	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.5	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	1.6	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.9	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.3	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	1.1	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.3	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.3	GO:1990782	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.3	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872) phosphofructokinase activity(GO:0008443)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.0	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900) translation regulator activity, nucleic acid binding(GO:0090079)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.4	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.0	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	1.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.2	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.0	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.0	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.2	GO:0043022	ribosome binding(GO:0043022)
0.0	0.0	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.0	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.0	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.0	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.0	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.0	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.0	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.0	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.0	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0045296	cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	PID INSULIN PATHWAY	Insulin Pathway
0.1	0.8	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.1	PID SHP2 PATHWAY	SHP2 signaling
0.1	2.5	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	2.2	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.2	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.3	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	1.0	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	1.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.0	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.6	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.2	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.5	PID BMP PATHWAY	BMP receptor signaling
0.0	0.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.4	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.2	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.7	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	3.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.2	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.2	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.3	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.1	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	1.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	1.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	2.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.6	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	1.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	2.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.5	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.9	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.0	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	1.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.4	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.6	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.1	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.0	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.3	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.0	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.2	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.2	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.1	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.0	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters

Results for PAX6

Z-value: 2.26

Motif logo

Transcription factors associated with PAX6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the PAX6 motif across conditions

Conditions sorted by the z-value of the PAX6 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: