Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PAX6

Z-value: 2.26

Motif logo

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Transcription factors associated with PAX6

Gene Symbol Gene ID Gene Info
ENSG00000007372.16 PAX6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
PAX6chr11_31827177_3182732812170.4958630.827.3e-03Click!
PAX6chr11_31820977_3182114074110.2094290.742.2e-02Click!
PAX6chr11_31831142_318312936360.7177920.732.6e-02Click!
PAX6chr11_31819962_3182022583760.2057600.655.9e-02Click!
PAX6chr11_31892590_31892741531560.1328640.608.5e-02Click!

Activity of the PAX6 motif across conditions

Conditions sorted by the z-value of the PAX6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_163040363_163040678 1.84 RGS4
regulator of G-protein signaling 4
1314
0.56
chr9_13568681_13569117 1.19 MPDZ
multiple PDZ domain protein
289310
0.01
chr8_104197199_104197403 0.90 RP11-318M2.2

12933
0.14
chr5_83680091_83680703 0.85 CTD-2269F5.1

23
0.71
chr10_60235657_60235933 0.83 BICC1
bicaudal C homolog 1 (Drosophila)
37105
0.2
chr2_188417834_188418053 0.79 AC007319.1

933
0.47
chr13_96295623_96295774 0.77 DZIP1
DAZ interacting zinc finger protein 1
181
0.96
chr6_27516181_27516437 0.76 ENSG00000206671
.
47882
0.13
chr1_67000815_67001114 0.76 SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
999
0.67
chr2_36924555_36924939 0.76 VIT
vitrin
727
0.75
chr12_46518814_46519037 0.70 SCAF11
SR-related CTD-associated factor 11
133022
0.05
chr6_21310055_21310473 0.68 SOX4
SRY (sex determining region Y)-box 4
283708
0.01
chr4_74809740_74810515 0.68 PF4
platelet factor 4
37714
0.11
chr1_172313169_172313650 0.67 ENSG00000252354
.
3874
0.23
chr3_157250943_157251353 0.67 VEPH1
ventricular zone expressed PH domain-containing 1
247
0.94
chr18_53068422_53068903 0.66 TCF4
transcription factor 4
96
0.98
chr4_39522963_39523180 0.66 UGDH
UDP-glucose 6-dehydrogenase
5106
0.17
chr4_55093553_55093862 0.66 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
1557
0.51
chr6_138976372_138976635 0.65 RP11-390P2.4

37182
0.17
chr2_66664825_66665240 0.65 MEIS1
Meis homeobox 1
93
0.96
chr12_16500618_16501134 0.64 MGST1
microsomal glutathione S-transferase 1
145
0.97
chr1_221892176_221892506 0.64 DUSP10
dual specificity phosphatase 10
18461
0.29
chr8_32506055_32506353 0.61 NRG1
neuregulin 1
847
0.76
chr2_218806750_218806920 0.59 TNS1
tensin 1
1958
0.38
chr3_168759646_168760009 0.59 MECOM
MDS1 and EVI1 complex locus
85995
0.11
chr2_217237286_217237473 0.59 MARCH4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
629
0.69
chr6_53934757_53935103 0.59 MLIP-AS1
MLIP antisense RNA 1
9594
0.22
chr18_56029142_56029527 0.58 RP11-845C23.2

9464
0.19
chr1_240264021_240264305 0.57 FMN2
formin 2
8983
0.26
chr3_104078695_104079148 0.57 ENSG00000265076
.
305281
0.01
chr18_32073627_32073820 0.57 DTNA
dystrobrevin, alpha
144
0.98
chr7_43288991_43289248 0.56 AC004692.4

252
0.93
chr12_66221542_66221865 0.56 HMGA2
high mobility group AT-hook 2
2800
0.29
chr3_151791319_151791512 0.56 RP11-454C18.2

145452
0.04
chr1_179111876_179112093 0.56 ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
195
0.95
chr9_14096707_14097036 0.55 NFIB
nuclear factor I/B
83920
0.11
chr1_110933695_110934011 0.55 SLC16A4
solute carrier family 16, member 4
149
0.93
chr7_134465998_134466492 0.55 CALD1
caldesmon 1
1816
0.49
chr8_38153609_38153832 0.55 RP11-513D5.5

20314
0.11
chr2_238320302_238320453 0.55 COL6A3
collagen, type VI, alpha 3
2414
0.31
chr3_173302672_173303490 0.54 NLGN1
neuroligin 1
371
0.93
chr4_4784046_4784388 0.54 MSX1
msh homeobox 1
77176
0.11
chr13_67708586_67709053 0.54 PCDH9
protocadherin 9
93753
0.09
chr21_17568279_17568430 0.53 ENSG00000201025
.
88735
0.1
chr18_60092781_60092970 0.52 RP11-640A1.3

47512
0.14
chr4_186696107_186696537 0.52 SORBS2
sorbin and SH3 domain containing 2
108
0.98
chr11_68780147_68780456 0.51 RP11-554A11.6

402
0.45
chr16_86774936_86775161 0.51 FOXL1
forkhead box L1
162933
0.03
chr8_104155486_104155705 0.51 C8orf56
chromosome 8 open reading frame 56
1892
0.22
chr17_67055930_67056124 0.51 ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
1020
0.57
chr6_148593126_148593282 0.51 SASH1
SAM and SH3 domain containing 1
236
0.93
chr13_33858654_33859881 0.51 STARD13
StAR-related lipid transfer (START) domain containing 13
625
0.76
chr4_81192022_81192173 0.51 FGF5
fibroblast growth factor 5
4304
0.29
chr9_79502750_79503010 0.51 PRUNE2
prune homolog 2 (Drosophila)
18121
0.27
chr3_99357829_99358140 0.50 COL8A1
collagen, type VIII, alpha 1
530
0.85
chr2_159788512_159788928 0.50 ENSG00000222300
.
3777
0.25
chr15_63339134_63339580 0.50 TPM1
tropomyosin 1 (alpha)
1208
0.41
chr8_131960988_131961496 0.50 RP11-737F9.1

13587
0.24
chr4_148947373_148947715 0.50 RP11-76G10.1

120078
0.06
chr4_15471787_15471987 0.49 CC2D2A
coiled-coil and C2 domain containing 2A
250
0.93
chr17_42906288_42907233 0.49 GJC1
gap junction protein, gamma 1, 45kDa
302
0.85
chr13_24146066_24146217 0.49 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
1338
0.59
chr10_33620428_33620906 0.49 NRP1
neuropilin 1
2643
0.37
chr14_93736061_93736314 0.49 BTBD7
BTB (POZ) domain containing 7
24308
0.15
chr1_247506079_247506341 0.49 ZNF496
zinc finger protein 496
11165
0.18
chr15_79854706_79854896 0.49 KIAA1024
KIAA1024
129943
0.05
chr10_31435945_31436159 0.48 ENSG00000263578
.
81076
0.1
chr2_65585991_65586247 0.48 SPRED2
sprouty-related, EVH1 domain containing 2
7665
0.24
chr8_38585652_38586394 0.48 TACC1
transforming, acidic coiled-coil containing protein 1
82
0.97
chr15_49098304_49098486 0.48 CEP152
centrosomal protein 152kDa
4396
0.19
chr1_179111271_179111703 0.48 ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
692
0.72
chr8_67468064_67468215 0.48 ENSG00000206949
.
54593
0.1
chr5_37810419_37810701 0.48 ENSG00000238335
.
8393
0.24
chr1_236147536_236147733 0.48 ENSG00000206803
.
68919
0.09
chr1_163044997_163045289 0.48 RGS4
regulator of G-protein signaling 4
3207
0.34
chr10_25007260_25007463 0.48 ARHGAP21
Rho GTPase activating protein 21
3434
0.35
chr12_46949518_46949939 0.48 SLC38A2
solute carrier family 38, member 2
183078
0.03
chrX_23686647_23686860 0.47 PRDX4
peroxiredoxin 4
1085
0.58
chr8_42063953_42065062 0.47 PLAT
plasminogen activator, tissue
576
0.71
chr4_119094947_119095286 0.47 ENSG00000269893
.
105229
0.08
chr7_42355171_42355392 0.47 GLI3
GLI family zinc finger 3
78623
0.12
chr7_93552513_93552820 0.47 GNG11
guanine nucleotide binding protein (G protein), gamma 11
1655
0.33
chr7_138348504_138348889 0.47 SVOPL
SVOP-like
273
0.93
chr4_55097787_55097981 0.47 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
1395
0.55
chr1_231002708_231002859 0.47 C1orf198
chromosome 1 open reading frame 198
1616
0.28
chr4_74734701_74735215 0.47 CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
163
0.94
chr15_30922047_30922198 0.47 ARHGAP11B
Rho GTPase activating protein 11B
3243
0.11
chr18_52357258_52357685 0.47 RAB27B
RAB27B, member RAS oncogene family
27620
0.24
chr9_35516264_35516818 0.47 RUSC2
RUN and SH3 domain containing 2
22088
0.14
chr13_98630173_98630324 0.47 IPO5
importin 5
1031
0.66
chr4_181928076_181928259 0.46 ENSG00000251742
.
828094
0.0
chr6_155005040_155005564 0.46 SCAF8
SR-related CTD-associated factor 8
49157
0.17
chr4_113773971_113774122 0.46 RP11-119H12.6

29440
0.18
chr5_89317042_89317197 0.46 ENSG00000264342
.
4582
0.37
chr7_19154419_19154620 0.46 AC003986.6

2422
0.22
chr6_80254303_80254623 0.46 LCA5
Leber congenital amaurosis 5
7288
0.3
chr4_86853777_86853998 0.46 ARHGAP24
Rho GTPase activating protein 24
2461
0.32
chr2_39662878_39663172 0.46 AC007246.3

753
0.54
chr4_85888141_85888634 0.46 WDFY3
WD repeat and FYVE domain containing 3
843
0.73
chr7_147097413_147097615 0.46 ENSG00000221442
.
22301
0.28
chrX_114828631_114828846 0.46 PLS3
plastin 3
873
0.64
chr18_25703623_25703892 0.46 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
26564
0.27
chr6_144570442_144570614 0.45 UTRN
utrophin
36309
0.2
chr10_25008347_25008498 0.45 ARHGAP21
Rho GTPase activating protein 21
2373
0.41
chr15_63446474_63446661 0.45 RPS27L
ribosomal protein S27-like
2406
0.28
chr12_106530238_106530817 0.45 NUAK1
NUAK family, SNF1-like kinase, 1
3284
0.3
chrX_83756622_83756797 0.45 HDX
highly divergent homeobox
690
0.48
chr19_9473504_9474272 0.45 ZNF177
zinc finger protein 177
181
0.93
chr7_19145980_19146451 0.45 AC003986.6

5882
0.17
chr6_135679919_135680436 0.44 AHI1
Abelson helper integration site 1
52469
0.13
chr1_201425782_201426096 0.44 PHLDA3
pleckstrin homology-like domain, family A, member 3
12373
0.15
chr7_94004298_94004620 0.44 COL1A2
collagen, type I, alpha 2
19414
0.26
chr10_95274973_95275229 0.44 ENSG00000212396
.
4664
0.19
chr16_53244996_53245358 0.44 CHD9
chromodomain helicase DNA binding protein 9
2814
0.29
chr6_94494975_94495370 0.44 ENSG00000252249
.
93652
0.1
chr9_120497648_120497799 0.44 ENSG00000251847
.
3974
0.26
chr10_52191139_52191567 0.44 AC069547.2
Uncharacterized protein
38587
0.15
chr5_88178054_88178448 0.44 MEF2C
myocyte enhancer factor 2C
713
0.52
chr2_41837870_41838465 0.44 ENSG00000221372
.
14641
0.29
chr8_123801020_123801334 0.44 ZHX2
zinc fingers and homeoboxes 2
7544
0.22
chrX_33227749_33227900 0.44 DMD
dystrophin
1605
0.57
chr3_112354765_112355126 0.43 CCDC80
coiled-coil domain containing 80
1999
0.4
chr1_193304797_193304948 0.43 B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
149088
0.04
chr13_113365888_113366065 0.43 ENSG00000264726
.
6252
0.2
chr13_93880393_93880808 0.43 GPC6
glypican 6
1505
0.58
chr6_64017987_64018177 0.43 LGSN
lengsin, lens protein with glutamine synthetase domain
11800
0.29
chr2_44518253_44518404 0.43 SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
5694
0.21
chr6_169652381_169652976 0.43 THBS2
thrombospondin 2
432
0.89
chr5_57555667_57556212 0.43 ENSG00000238899
.
189924
0.03
chr8_6149062_6149390 0.43 RP11-115C21.2

114837
0.06
chr21_30673835_30674113 0.43 BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
851
0.62
chr15_59622460_59622641 0.43 ENSG00000199512
.
11066
0.14
chr16_86619409_86619937 0.43 FOXL1
forkhead box L1
7558
0.18
chr16_69309884_69310035 0.43 RP11-343C2.11
Uncharacterized protein
23626
0.1
chr7_19155354_19155672 0.42 TWIST1
twist family bHLH transcription factor 1
1782
0.28
chr7_100773540_100774051 0.42 SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
3416
0.13
chr7_94964422_94964573 0.42 PON1
paraoxonase 1
10478
0.21
chr1_227503732_227504041 0.42 CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
997
0.69
chr13_24007256_24007423 0.42 SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
502
0.88
chr2_133105502_133105810 0.42 ENSG00000252705
.
58775
0.12
chr2_198538241_198538478 0.42 RFTN2
raftlin family member 2
2360
0.29
chr5_22212541_22212718 0.42 CDH12
cadherin 12, type 2 (N-cadherin 2)
1230
0.59
chr10_128995077_128995475 0.41 FAM196A
family with sequence similarity 196, member A
854
0.75
chr7_14418809_14419008 0.41 ENSG00000252374
.
368520
0.01
chr12_125073530_125073715 0.41 NCOR2
nuclear receptor corepressor 2
21612
0.27
chr4_134068181_134068851 0.41 PCDH10
protocadherin 10
1954
0.52
chr18_8609852_8610932 0.41 RAB12
RAB12, member RAS oncogene family
949
0.6
chr3_55514769_55515136 0.41 WNT5A
wingless-type MMTV integration site family, member 5A
272
0.94
chr15_96869932_96870158 0.41 NR2F2-AS1
NR2F2 antisense RNA 1
205
0.86
chr6_74406883_74407034 0.41 RP11-553A21.3

1104
0.37
chr2_239758985_239759136 0.41 TWIST2
twist family bHLH transcription factor 2
2387
0.39
chr10_18294252_18294909 0.41 SLC39A12-AS1
SLC39A12 antisense RNA 1
1619
0.47
chr17_60905052_60905372 0.41 MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
19507
0.23
chr15_64231749_64232239 0.40 RP11-111E14.1

11521
0.22
chr10_34827521_34827675 0.40 PARD3
par-3 family cell polarity regulator
111939
0.07
chr3_87035332_87035763 0.40 VGLL3
vestigial like 3 (Drosophila)
4305
0.37
chr14_56808787_56808938 0.40 TMEM260
transmembrane protein 260
146210
0.04
chr1_156540904_156541055 0.40 IQGAP3
IQ motif containing GTPase activating protein 3
1353
0.26
chr4_11652300_11652527 0.40 HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
221024
0.02
chr11_7911988_7912218 0.40 ENSG00000252769
.
1277
0.37
chr4_16899723_16900066 0.40 LDB2
LIM domain binding 2
291
0.95
chr10_79730818_79731123 0.39 DLG5-AS1
DLG5 antisense RNA 1
43840
0.12
chr2_175831081_175831232 0.39 ENSG00000201425
.
11375
0.19
chr3_29324199_29324416 0.39 RBMS3
RNA binding motif, single stranded interacting protein 3
1200
0.55
chr22_46461260_46461448 0.39 RP6-109B7.4

4417
0.11
chr5_321961_322616 0.39 AHRR
aryl-hydrocarbon receptor repressor
397
0.84
chr1_9254295_9254446 0.39 H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
40464
0.12
chr12_32261770_32262117 0.39 RP11-843B15.2

1481
0.38
chr11_16813436_16813790 0.39 PLEKHA7
pleckstrin homology domain containing, family A member 7
20417
0.2
chr2_177501805_177501995 0.39 ENSG00000252027
.
27504
0.25
chr6_149354145_149354352 0.39 RP11-162J8.3

539
0.84
chr7_83822850_83823057 0.39 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
1264
0.65
chr2_159610172_159610621 0.39 AC005042.4

18882
0.21
chr10_33723534_33723685 0.39 NRP1
neuropilin 1
98419
0.08
chr11_101453394_101453891 0.38 TRPC6
transient receptor potential cation channel, subfamily C, member 6
592
0.84
chr8_120649956_120650241 0.38 ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
922
0.68
chr5_39423074_39423254 0.38 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
1806
0.48
chr12_15490350_15490501 0.38 RERG
RAS-like, estrogen-regulated, growth inhibitor
11107
0.24
chr3_168959825_168960526 0.38 MECOM
MDS1 and EVI1 complex locus
26851
0.26
chr5_137475160_137475365 0.38 NME5
NME/NM23 family member 5
158
0.92
chr6_20438864_20439015 0.38 E2F3-IT1
E2F3 intronic transcript 1 (non-protein coding)
887
0.51
chr2_74691535_74692741 0.38 MOGS
mannosyl-oligosaccharide glucosidase
351
0.67
chr5_54456456_54456818 0.38 GPX8
glutathione peroxidase 8 (putative)
639
0.58
chr15_59599194_59599413 0.38 ENSG00000199512
.
34313
0.11
chr13_111922547_111922806 0.38 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
29109
0.2
chr5_91977319_91977616 0.38 ENSG00000221810
.
75753
0.13
chr1_230367637_230367834 0.38 RP5-956O18.2

36494
0.18
chr3_61833858_61834009 0.37 ENSG00000252420
.
109030
0.08
chr6_2789380_2789655 0.37 WRNIP1
Werner helicase interacting protein 1
20510
0.17
chr7_95239102_95239253 0.37 AC002451.3

69
0.98
chr7_94027821_94027972 0.37 COL1A2
collagen, type I, alpha 2
4023
0.33
chr16_89990965_89991193 0.37 TUBB3
Tubulin beta-3 chain
1305
0.26
chr12_45428919_45429070 0.37 RP11-478B9.1

15690
0.21
chr18_54046287_54046510 0.37 TXNL1
thioredoxin-like 1
235324
0.02
chr7_120380736_120380895 0.37 KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
83
0.98
chr18_43303934_43304085 0.37 SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
83
0.97
chr2_197143535_197143686 0.37 ENSG00000264627
.
10523
0.2
chr6_53935109_53935336 0.36 MLIP-AS1
MLIP antisense RNA 1
9302
0.22
chr14_100260916_100261174 0.36 EML1
echinoderm microtubule associated protein like 1
1273
0.55
chr9_134055367_134055573 0.36 NUP214
nucleoporin 214kDa
10038
0.15

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PAX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.2 0.7 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.2 0.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.4 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.2 0.9 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 0.8 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.2 0.6 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 1.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 0.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 0.5 GO:0031223 auditory behavior(GO:0031223)
0.2 0.5 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.9 GO:0016264 gap junction assembly(GO:0016264)
0.1 0.5 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.1 0.9 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.4 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1 1.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.9 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1 0.4 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.6 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.4 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.1 GO:0021889 olfactory bulb interneuron differentiation(GO:0021889)
0.1 0.3 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.1 0.3 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.3 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.6 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.3 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.4 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.6 GO:0015840 urea transport(GO:0015840)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.4 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.1 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.6 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1 0.2 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.5 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1 0.2 GO:0030202 heparin metabolic process(GO:0030202)
0.1 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.2 GO:0036303 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1 0.2 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.1 0.5 GO:0060039 pericardium development(GO:0060039)
0.1 0.4 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1 0.2 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.2 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.1 0.8 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.1 0.1 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.1 0.5 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742) histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.2 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.1 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.1 GO:0032347 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1 0.1 GO:0007412 axon target recognition(GO:0007412)
0.1 1.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.3 GO:0010107 potassium ion import(GO:0010107)
0.1 0.7 GO:0035329 hippo signaling(GO:0035329)
0.1 0.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.4 GO:0015871 choline transport(GO:0015871)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.1 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.1 0.2 GO:0030091 protein repair(GO:0030091)
0.1 0.1 GO:0060841 venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.1 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.2 GO:0048539 bone marrow development(GO:0048539)
0.1 0.1 GO:0060068 vagina development(GO:0060068)
0.1 0.3 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.1 0.2 GO:0016241 regulation of macroautophagy(GO:0016241)
0.1 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.1 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.1 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.3 GO:0031641 regulation of myelination(GO:0031641)
0.1 0.1 GO:0090009 primitive streak formation(GO:0090009)
0.1 0.3 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.1 0.4 GO:0006228 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.1 0.2 GO:0021794 thalamus development(GO:0021794)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.7 GO:0071453 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0002604 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.4 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0090594 wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594) connective tissue replacement(GO:0097709)
0.0 0.3 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.8 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.3 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.2 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:1904063 negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0048867 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.0 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.1 GO:1901374 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.1 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.3 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.1 GO:0032261 purine nucleotide salvage(GO:0032261)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0034444 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.2 GO:0031000 response to caffeine(GO:0031000)
0.0 0.1 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0031620 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.2 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.0 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.1 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 1.3 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.3 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.0 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0045683 negative regulation of epidermal cell differentiation(GO:0045605) negative regulation of epidermis development(GO:0045683)
0.0 0.1 GO:0060192 negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0006991 response to sterol depletion(GO:0006991)
0.0 0.2 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.0 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.0 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.0 0.1 GO:0070091 glucagon secretion(GO:0070091)
0.0 0.0 GO:1903306 negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.2 GO:0001508 action potential(GO:0001508)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.2 GO:0090659 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0048566 embryonic digestive tract development(GO:0048566)
0.0 0.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.3 GO:0042551 neuron maturation(GO:0042551)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0003211 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.1 GO:0060620 sterol import(GO:0035376) regulation of cholesterol import(GO:0060620) cholesterol import(GO:0070508) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.7 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.0 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0060009 Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0 0.0 GO:0022601 menstrual cycle phase(GO:0022601)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.0 GO:0052556 positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0 0.1 GO:0043084 penile erection(GO:0043084)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.0 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.0 GO:0071267 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.0 GO:0055023 positive regulation of cardiac muscle tissue growth(GO:0055023) positive regulation of cardiac muscle tissue development(GO:0055025) positive regulation of cardiac muscle cell proliferation(GO:0060045)
0.0 0.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.0 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0061383 trabecula formation(GO:0060343) bone trabecula formation(GO:0060346) trabecula morphogenesis(GO:0061383) bone trabecula morphogenesis(GO:0061430)
0.0 0.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.0 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.0 GO:0051299 centrosome separation(GO:0051299)
0.0 0.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.1 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.0 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.0 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0035136 forelimb morphogenesis(GO:0035136)
0.0 0.2 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.0 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.0 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.0 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.0 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.0 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.0 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.0 0.1 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123) positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.4 GO:0071773 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.1 GO:0008347 glial cell migration(GO:0008347)
0.0 1.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.0 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.0 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.1 GO:0007530 sex determination(GO:0007530)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.0 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.0 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.0 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0007616 long-term memory(GO:0007616)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.0 GO:0021554 optic nerve development(GO:0021554)
0.0 0.1 GO:0007215 glutamate receptor signaling pathway(GO:0007215)
0.0 0.3 GO:0042303 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 0.0 GO:0003401 axis elongation(GO:0003401)
0.0 0.2 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.0 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.3 GO:0001764 neuron migration(GO:0001764)
0.0 0.1 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.0 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.1 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.2 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.2 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.0 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.2 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0099518 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.0 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0006893 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.0 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.6 GO:0070852 cell body fiber(GO:0070852)
0.1 1.0 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.9 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0032059 bleb(GO:0032059)
0.1 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.9 GO:0098644 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) complex of collagen trimers(GO:0098644)
0.1 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.6 GO:0005916 fascia adherens(GO:0005916)
0.1 0.8 GO:0043034 costamere(GO:0043034)
0.1 0.8 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1 0.3 GO:0005915 zonula adherens(GO:0005915)
0.1 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.1 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.4 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0043205 fibril(GO:0043205)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 2.1 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 1.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0034704 calcium channel complex(GO:0034704)
0.0 1.6 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 2.4 GO:0030016 myofibril(GO:0030016)
0.0 4.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.7 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.0 GO:0044447 axoneme part(GO:0044447)
0.0 0.5 GO:0032155 cell division site(GO:0032153) cell division site part(GO:0032155)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.0 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.6 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.0 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.7 GO:0045177 apical part of cell(GO:0045177)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0032421 stereocilium bundle(GO:0032421)
0.0 0.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3 0.8 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.2 0.7 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.2 0.7 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.8 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.8 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0005113 patched binding(GO:0005113)
0.1 1.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.1 GO:0043559 insulin binding(GO:0043559)
0.1 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 1.1 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872) phosphofructokinase activity(GO:0008443)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900) translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.0 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.2 GO:0043022 ribosome binding(GO:0043022)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.0 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.0 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.0 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0031782 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.0 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.0 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 PID INSULIN PATHWAY Insulin Pathway
0.1 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.1 PID SHP2 PATHWAY SHP2 signaling
0.1 2.5 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.1 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 2.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 2.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.0 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.0 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.1 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.0 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters