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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PAX7_NOBOX

Z-value: 0.74

Motif logo

Transcription factors associated with PAX7_NOBOX

Gene Symbol	Gene ID	Gene Info
PAX7 Ensembl NCBI GeneCards UniProt	ENSG00000009709.7	PAX7
NOBOX Ensembl NCBI GeneCards UniProt	ENSG00000106410.10	NOBOX

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
NOBOX	chr7_144104551_144104702	2694	0.244758	0.82	6.4e-03	Click!
NOBOX	chr7_144113392_144113543	6147	0.187773	0.82	7.1e-03	Click!
NOBOX	chr7_144104809_144104960	2436	0.260426	0.64	6.3e-02	Click!
NOBOX	chr7_144113151_144113302	5906	0.189144	0.63	6.6e-02	Click!
NOBOX	chr7_144081989_144082140	18722	0.133433	0.54	1.4e-01	Click!
PAX7	chr1_18957647_18957941	221	0.963424	0.83	6.1e-03	Click!
PAX7	chr1_18957463_18957614	38	0.987288	0.81	8.0e-03	Click!
PAX7	chr1_19020395_19020546	62452	0.134235	0.80	9.9e-03	Click!
PAX7	chr1_18970260_18970411	12317	0.285708	0.68	4.3e-02	Click!
PAX7	chr1_18970063_18970214	12120	0.286284	0.67	4.7e-02	Click!

Activity of the PAX7_NOBOX motif across conditions

Conditions sorted by the z-value of the PAX7_NOBOX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_115135696_115136278	0.63	TBX3	T-box 3	14018	0.21
chr20_14315841_14316127	0.59	FLRT3	fibronectin leucine rich transmembrane protein 3	2270	0.36
chr1_45083000_45083241	0.58	RNF220	ring finger protein 220	8878	0.17
chr5_3597777_3597928	0.55	IRX1	iroquois homeobox 1	1684	0.41
chr6_56528559_56528710	0.54	DST	dystonin	20840	0.27
chr3_67581837_67581988	0.52	SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	3266	0.41
chr1_200865204_200865355	0.48	C1orf106	chromosome 1 open reading frame 106	1330	0.42
chr2_23603304_23603524	0.46	KLHL29	kelch-like family member 29	4674	0.35
chr11_131780111_131780399	0.46	NTM	neurotrimin	642	0.77
chr6_125855681_125855832	0.46	RP11-735G4.1		160286	0.04
chr4_90581488_90581639	0.44	RP11-115D19.1		21100	0.27
chr1_159111648_159111897	0.43	AIM2	absent in melanoma 2	1474	0.37
chrX_135231057_135231247	0.43	FHL1	four and a half LIM domains 1	415	0.86
chr5_73839186_73839374	0.42	HEXB	hexosaminidase B (beta polypeptide)	96568	0.07
chr11_69454777_69455129	0.42	CCND1	cyclin D1	902	0.63
chr5_36591027_36591178	0.42	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	15355	0.27
chr1_230223080_230223231	0.41	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	20137	0.23
chr22_18575359_18575510	0.41	XXbac-B476C20.9		13784	0.14
chr7_80377911_80378104	0.40	CD36	CD36 molecule (thrombospondin receptor)	75315	0.12
chr7_70060715_70061143	0.39	AUTS2	autism susceptibility candidate 2	133196	0.06
chr9_9701186_9701337	0.39	ENSG00000265735	.	259201	0.02
chr13_37397601_37397752	0.39	RFXAP	regulatory factor X-associated protein	4315	0.24
chr9_98188423_98189086	0.39	PTCH1	patched 1	54013	0.12
chr1_1099465_1099616	0.39	ENSG00000207730	.	2944	0.11
chr7_32929941_32930760	0.38	KBTBD2	kelch repeat and BTB (POZ) domain containing 2	415	0.87
chr2_192176773_192176924	0.38	MYO1B	myosin IB	35237	0.19
chr11_24518160_24518510	0.37	LUZP2	leucine zipper protein 2	389	0.91
chr6_33589286_33590289	0.37	ITPR3	inositol 1,4,5-trisphosphate receptor, type 3	626	0.65
chr4_57984994_57985389	0.37	IGFBP7	insulin-like growth factor binding protein 7	8640	0.18
chr9_72745702_72745853	0.37	MAMDC2-AS1	MAMDC2 antisense RNA 1	17001	0.22
chr19_13127591_13127981	0.36	CTC-239J10.1		2461	0.15
chr6_27342407_27343330	0.36	ZNF391	zinc finger protein 391	13629	0.22
chr14_74724486_74725063	0.36	VSX2	visual system homeobox 2	18599	0.14
chr4_27219592_27219774	0.35	ENSG00000222206	.	5366	0.35
chr11_119572371_119572522	0.35	PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	26817	0.16
chr2_113958350_113958501	0.35	PSD4	pleckstrin and Sec7 domain containing 4	4568	0.16
chr2_163171316_163171467	0.35	IFIH1	interferon induced with helicase C domain 1	3803	0.25
chr4_23975239_23975390	0.35	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	83614	0.11
chr18_61555988_61556228	0.35	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	1115	0.49
chr8_59027426_59027596	0.34	FAM110B	family with sequence similarity 110, member B	120398	0.07
chr13_23092547_23092698	0.34	ENSG00000253094	.	284662	0.01
chr22_46929020_46929201	0.34	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1	2081	0.33
chr11_37525950_37526107	0.34	ENSG00000251838	.	197742	0.03
chr20_51273685_51273836	0.34	TSHZ2	teashirt zinc finger homeobox 2	315186	0.01
chr10_75938020_75938413	0.34	ADK	adenosine kinase	1695	0.42
chr13_110757726_110757877	0.34	ENSG00000265885	.	7303	0.31
chr22_34248307_34248458	0.34	LARGE	like-glycosyltransferase	9230	0.27
chr14_81789932_81790083	0.34	STON2	stonin 2	46730	0.17
chr3_54897831_54897982	0.33	CACNA2D3-AS1	CACNA2D3 antisense RNA 1	37376	0.21
chr4_160357796_160357947	0.33	ENSG00000251979	.	70309	0.12
chr12_29716327_29716478	0.32	TMTC1	transmembrane and tetratricopeptide repeat containing 1	40755	0.16
chr5_96000350_96000501	0.32	CAST	calpastatin	1668	0.37
chr18_59619337_59619488	0.32	RNF152	ring finger protein 152	57948	0.16
chr15_99297407_99297593	0.32	ENSG00000264480	.	30155	0.19
chr7_1443631_1443991	0.32	MICALL2	MICAL-like 2	55151	0.11
chr4_113331922_113332073	0.32	RP11-402J6.1		104544	0.06
chr13_39327903_39328054	0.32	ENSG00000252795	.	25583	0.19
chrX_3264180_3264467	0.32	MXRA5	matrix-remodelling associated 5	359	0.92
chr15_93999319_93999470	0.32	ENSG00000212063	.	169842	0.04
chr10_126315472_126315623	0.32	FAM53B-AS1	FAM53B antisense RNA 1	76647	0.09
chr2_113539557_113539708	0.31	IL1A	interleukin 1, alpha	2535	0.25
chr13_30415572_30415723	0.31	UBL3	ubiquitin-like 3	9174	0.3
chr8_70622919_70623070	0.31	RP11-102F4.2		2631	0.31
chr11_14375529_14375805	0.31	RRAS2	related RAS viral (r-ras) oncogene homolog 2	379	0.91
chr15_98835948_98836124	0.30	FAM169B	family with sequence similarity 169, member B	193171	0.03
chr16_66851667_66851818	0.30	NAE1	NEDD8 activating enzyme E1 subunit 1	7140	0.13
chr9_124846791_124846942	0.30	TTLL11	tubulin tyrosine ligase-like family, member 11	9019	0.2
chr4_139635357_139635508	0.30	ENSG00000238971	.	97488	0.08
chr7_100492646_100493161	0.30	ACHE	acetylcholinesterase (Yt blood group)	579	0.57
chr8_112438072_112438223	0.30	ENSG00000222146	.	722907	0.0
chr1_181050920_181051071	0.30	IER5	immediate early response 5	6643	0.23
chr1_97033525_97033676	0.30	ENSG00000241992	.	15165	0.29
chr20_1892625_1892776	0.30	SIRPA	signal-regulatory protein alpha	16758	0.21
chr8_76807046_76807197	0.30	ENSG00000238595	.	1982	0.49
chr11_26604890_26605185	0.30	MUC15	mucin 15, cell surface associated	11257	0.3
chr5_100168975_100169126	0.30	ENSG00000221263	.	16781	0.26
chr3_151034381_151034532	0.30	GPR87	G protein-coupled receptor 87	284	0.9
chr9_92032170_92032321	0.29	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	1503	0.49
chr22_19794405_19794556	0.29	C22orf29	chromosome 22 open reading frame 29	47859	0.1
chrX_150695771_150695922	0.29	PASD1	PAS domain containing 1	36248	0.2
chr15_101899572_101899723	0.29	PCSK6	proprotein convertase subtilisin/kexin type 6	6820	0.2
chr7_121585085_121585236	0.29	PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	71745	0.12
chr10_6763782_6764322	0.29	PRKCQ	protein kinase C, theta	141789	0.05
chr10_108111933_108112084	0.29	SORCS1	sortilin-related VPS10 domain containing receptor 1	259737	0.02
chr6_41472777_41473161	0.29	RP11-328M4.2		40843	0.13
chr3_49447935_49448923	0.29	RHOA	ras homolog family member A	932	0.32
chr9_89952337_89952906	0.29	ENSG00000212421	.	77256	0.11
chr15_99449448_99449599	0.29	RP11-654A16.1		12759	0.21
chr12_56917781_56918152	0.29	RBMS2	RNA binding motif, single stranded interacting protein 2	2183	0.23
chr7_98970111_98970529	0.29	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	1552	0.28
chr12_125179754_125179913	0.29	SCARB1	scavenger receptor class B, member 1	122420	0.06
chr20_14316163_14316462	0.29	FLRT3	fibronectin leucine rich transmembrane protein 3	1942	0.4
chr14_94641841_94642049	0.28	PPP4R4	protein phosphatase 4, regulatory subunit 4	147	0.96
chr18_30310087_30311054	0.28	AC012123.1	Uncharacterized protein	39188	0.17
chr3_79028408_79028559	0.28	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	39211	0.19
chr3_88191159_88191414	0.28	ZNF654	zinc finger protein 654	3032	0.24
chr15_96903910_96904291	0.28	AC087477.1	Uncharacterized protein	387	0.85
chr17_12569246_12569498	0.28	MYOCD	myocardin	66	0.98
chr2_36589291_36589442	0.28	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	5752	0.33
chr8_143757309_143757460	0.28	PSCA	prostate stem cell antigen	4490	0.13
chr4_77067485_77067636	0.28	NUP54	nucleoporin 54kDa	1990	0.3
chr9_22239467_22239618	0.28	CDKN2B-AS1	CDKN2B antisense RNA 1	125865	0.06
chr17_40700695_40700889	0.28	HSD17B1	hydroxysteroid (17-beta) dehydrogenase 1	440	0.63
chr8_79469123_79469274	0.28	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	34268	0.19
chr15_36905175_36905326	0.28	C15orf41	chromosome 15 open reading frame 41	18149	0.26
chr2_119188658_119188833	0.28	INSIG2	insulin induced gene 2	342695	0.01
chr9_75771174_75771814	0.28	ANXA1	annexin A1	1076	0.66
chr13_79182716_79183828	0.27	POU4F1	POU class 4 homeobox 1	5599	0.19
chr6_132610665_132610816	0.27	MOXD1	monooxygenase, DBH-like 1	85464	0.09
chr1_30417491_30417642	0.27	ENSG00000222787	.	59817	0.17
chr13_74606153_74606483	0.27	KLF12	Kruppel-like factor 12	37132	0.24
chr4_173311851_173312002	0.27	GALNTL6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6	338330	0.01
chr7_92254665_92254816	0.27	FAM133B	family with sequence similarity 133, member B	35032	0.17
chr10_24754741_24755189	0.27	KIAA1217	KIAA1217	495	0.84
chr2_36597223_36597374	0.27	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	13684	0.29
chr3_170527527_170527678	0.27	ENSG00000222411	.	32359	0.19
chr14_53275157_53275308	0.27	GNPNAT1	glucosamine-phosphate N-acetyltransferase 1	16846	0.16
chr14_61445912_61446063	0.27	TRMT5	tRNA methyltransferase 5	1782	0.29
chr4_184961314_184961487	0.27	STOX2	storkhead box 2	38922	0.18
chr1_40471048_40471199	0.27	CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	34782	0.13
chr2_196281841_196281992	0.27	ENSG00000202206	.	96844	0.09
chr4_68636095_68636246	0.27	GNRHR	gonadotropin-releasing hormone receptor	16092	0.17
chr15_83951840_83952048	0.27	BNC1	basonuclin 1	127	0.97
chr4_77611462_77611724	0.27	AC107072.2		52817	0.12
chr8_39259417_39259568	0.27	ENSG00000252176	.	158964	0.04
chr1_246034788_246034939	0.27	RP11-83A16.1		161990	0.04
chr10_119302142_119302346	0.27	EMX2	empty spiracles homeobox 2	265	0.64
chr1_209761749_209761900	0.27	CAMK1G	calcium/calmodulin-dependent protein kinase IG	4750	0.21
chr5_44235116_44235267	0.27	FGF10-AS1	FGF10 antisense RNA 1	153643	0.04
chr5_140864017_140864278	0.27	PCDHGC4	protocadherin gamma subfamily C, 4	594	0.53
chr9_23769338_23769489	0.27	ELAVL2	ELAV like neuron-specific RNA binding protein 2	9960	0.33
chr8_31771478_31771629	0.26	NRG1-IT1	NRG1 intronic transcript 1 (non-protein coding)	112182	0.07
chr10_114552786_114553214	0.26	RP11-57H14.4		30249	0.21
chr14_55272428_55272636	0.26	SAMD4A	sterile alpha motif domain containing 4A	50981	0.13
chr4_153272766_153273041	0.26	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	1220	0.52
chr4_3387991_3388142	0.26	RGS12	regulator of G-protein signaling 12	5	0.98
chr6_106972751_106973424	0.26	AIM1	absent in melanoma 1	13357	0.2
chr8_62566222_62566373	0.26	ASPH	aspartate beta-hydroxylase	6931	0.24
chr3_31575511_31576107	0.26	STT3B	STT3B, subunit of the oligosaccharyltransferase complex (catalytic)	1527	0.55
chr2_184434080_184434231	0.26	ENSG00000238306	.	380008	0.01
chr3_100660155_100660398	0.26	ENSG00000201642	.	11195	0.24
chr4_75174481_75174674	0.26	EPGN	epithelial mitogen	237	0.93
chr7_139047352_139047690	0.26	C7orf55-LUC7L2	C7orf55-LUC7L2 readthrough	2867	0.19
chr10_134261699_134261957	0.26	C10orf91	chromosome 10 open reading frame 91	3135	0.24
chr12_95511000_95511151	0.26	FGD6	FYVE, RhoGEF and PH domain containing 6	326	0.91
chr17_79315981_79316442	0.26	TMEM105	transmembrane protein 105	11737	0.13
chr4_183455582_183455733	0.26	ENSG00000252343	.	14155	0.26
chr3_120277024_120277175	0.26	NDUFB4	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa	38057	0.18
chr21_17909068_17909746	0.26	ENSG00000207638	.	2002	0.33
chr3_189509857_189510008	0.26	TP63	tumor protein p63	2342	0.39
chr2_21444769_21444920	0.26	TDRD15	tudor domain containing 15	98055	0.09
chr16_86817661_86817812	0.25	FOXL1	forkhead box L1	205621	0.02
chr3_60921693_60921844	0.25	ENSG00000212211	.	79491	0.12
chr4_166361643_166362016	0.25	CPE	carboxypeptidase E	22451	0.23
chr7_79953980_79954131	0.25	ENSG00000240347	.	6486	0.23
chr12_125624965_125625116	0.25	AACS	acetoacetyl-CoA synthetase	11948	0.29
chr14_99713575_99713726	0.25	AL109767.1		15635	0.21
chr11_106239153_106239583	0.25	RP11-680E19.1		104326	0.08
chr1_198250905_198251056	0.25	NEK7	NIMA-related kinase 7	61051	0.16
chr2_119989374_119989591	0.25	STEAP3	STEAP family member 3, metalloreductase	8053	0.2
chr5_39058731_39058980	0.25	RICTOR	RPTOR independent companion of MTOR, complex 2	15636	0.24
chr12_50665639_50665877	0.25	LIMA1	LIM domain and actin binding 1	11509	0.13
chr3_129383548_129383699	0.25	TMCC1	transmembrane and coiled-coil domain family 1	8054	0.22
chr1_63212144_63212320	0.25	ATG4C	autophagy related 4C, cysteine peptidase	37574	0.17
chr16_59637744_59637895	0.25	ENSG00000200062	.	63789	0.15
chr1_3003277_3003428	0.25	PRDM16	PR domain containing 16	17577	0.18
chr2_207998546_207999225	0.25	KLF7	Kruppel-like factor 7 (ubiquitous)	24	0.98
chr6_64239754_64239905	0.25	PTP4A1	protein tyrosine phosphatase type IVA, member 1	42088	0.17
chr5_180523773_180523999	0.25	OR2V1	olfactory receptor, family 2, subfamily V, member 1	28418	0.12
chr14_52534801_52535890	0.25	NID2	nidogen 2 (osteonidogen)	367	0.89
chr17_18901833_18902110	0.25	FAM83G	family with sequence similarity 83, member G	5518	0.14
chr10_74436092_74436294	0.25	MCU	mitochondrial calcium uniporter	15696	0.15
chr2_55810508_55810659	0.25	ENSG00000212175	.	17744	0.15
chr15_67390777_67391884	0.25	SMAD3	SMAD family member 3	313	0.93
chr6_117804579_117805184	0.25	DCBLD1	discoidin, CUB and LCCL domain containing 1	1056	0.49
chr18_47385264_47385415	0.24	MYO5B	myosin VB	9123	0.15
chr2_188418561_188419245	0.24	AC007319.1		27	0.69
chr4_26344236_26344574	0.24	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	357	0.93
chr11_131170059_131170210	0.24	NTM	neurotrimin	70239	0.12
chr2_95689867_95690018	0.24	MAL	mal, T-cell differentiation protein	1487	0.32
chr10_29165095_29165348	0.24	ENSG00000199402	.	1785	0.43
chr2_511397_511548	0.24	TMEM18	transmembrane protein 18	164303	0.03
chr1_112491209_112491360	0.24	KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3	34134	0.17
chr22_46476561_46476775	0.24	FLJ27365	hsa-mir-4763	476	0.66
chr8_87188438_87188625	0.24	CTD-3118D11.3		4116	0.24
chr20_35830256_35830797	0.24	MROH8	maestro heat-like repeat family member 8	22535	0.17
chr4_77506894_77507309	0.24	ENSG00000265314	.	10397	0.17
chr7_19141522_19141673	0.24	AC003986.6		10500	0.16
chr15_47476270_47477144	0.24	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	409	0.87
chr14_29243474_29243665	0.24	C14orf23	chromosome 14 open reading frame 23	1568	0.33
chr1_198393639_198393891	0.24	ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	116039	0.07
chr2_149863937_149864088	0.24	LYPD6B	LY6/PLAUR domain containing 6B	30969	0.22
chr7_70048822_70048973	0.24	AUTS2	autism susceptibility candidate 2	145228	0.05
chr7_81040159_81040512	0.24	AC005008.2	Uncharacterized protein	223229	0.02
chr13_97927308_97927620	0.24	MBNL2	muscleblind-like splicing regulator 2	994	0.69
chr18_6730820_6730971	0.24	ARHGAP28	Rho GTPase activating protein 28	853	0.47
chr17_69531749_69531900	0.24	ENSG00000222563	.	224515	0.02
chr8_17657715_17658703	0.24	MTUS1	microtubule associated tumor suppressor 1	32	0.93
chr5_158036732_158037177	0.24	CTD-2363C16.1		373060	0.01
chr15_96878465_96878729	0.24	ENSG00000222651	.	2107	0.24

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX7_NOBOX

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.1	0.5	GO:0070141	response to UV-A(GO:0070141)
0.1	0.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.3	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.4	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.1	0.3	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.5	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.3	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	0.2	GO:0060677	ureteric bud elongation(GO:0060677)
0.1	0.3	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.1	0.3	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.3	GO:0008218	bioluminescence(GO:0008218)
0.1	0.7	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	0.2	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.3	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.2	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.3	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.1	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	0.2	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.2	GO:0044413	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.2	GO:0031223	auditory behavior(GO:0031223)
0.0	0.2	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	0.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.2	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.2	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.2	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.2	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.0	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.3	GO:0031579	membrane raft organization(GO:0031579)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0061117	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.1	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.2	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.0	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.1	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.0	GO:0060462	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.4	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.2	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.2	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.5	GO:0008038	neuron recognition(GO:0008038)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.4	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.1	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.1	GO:0032353	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0	0.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0072071	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.0	GO:0035112	genitalia morphogenesis(GO:0035112)
0.0	0.1	GO:0010659	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.3	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.2	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.2	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0002420	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.1	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0046541	saliva secretion(GO:0046541)
0.0	0.5	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.0	GO:0060033	Mullerian duct regression(GO:0001880) anatomical structure regression(GO:0060033)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.2	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0060438	trachea development(GO:0060438)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.0	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.1	GO:0045661	regulation of myoblast differentiation(GO:0045661)
0.0	0.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.0	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.0	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.0	GO:0055094	response to lipoprotein particle(GO:0055094)
0.0	0.1	GO:0051446	positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.0	GO:0072193	ureter development(GO:0072189) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0	0.1	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.4	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.2	GO:0051963	regulation of synapse assembly(GO:0051963)
0.0	0.1	GO:0032933	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.1	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.5	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.2	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.2	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.1	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.0	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.1	GO:0010894	negative regulation of steroid biosynthetic process(GO:0010894)
0.0	0.0	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.0	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0048535	lymph node development(GO:0048535)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.0	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.0	GO:0060179	male courtship behavior(GO:0008049) male mating behavior(GO:0060179)
0.0	0.0	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.0	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.3	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.0	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.1	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0060992	response to fungicide(GO:0060992)
0.0	0.0	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.1	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.2	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.0	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.0	GO:0090102	cochlea development(GO:0090102)
0.0	0.0	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.0	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0047496	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.0	GO:0060754	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	1.5	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.0	GO:0061213	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0034380	high-density lipoprotein particle assembly(GO:0034380)
0.0	0.2	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.0	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.4	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.0	GO:0003097	renal water transport(GO:0003097)
0.0	0.2	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.0	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.0	GO:0090493	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.1	GO:0008347	glial cell migration(GO:0008347)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.1	GO:0030826	regulation of cGMP biosynthetic process(GO:0030826)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.2	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.4	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.3	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.3	GO:0005605	basal lamina(GO:0005605)
0.0	0.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0045178	basal part of cell(GO:0045178)
0.0	0.1	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.6	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.0	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0031430	M band(GO:0031430)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.0	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.3	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.2	GO:0001533	cornified envelope(GO:0001533)
0.0	0.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.2	GO:0030057	desmosome(GO:0030057)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.2	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0004104	cholinesterase activity(GO:0004104)
0.1	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	0.2	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.6	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.3	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.3	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.4	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.9	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.0	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.0	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.0	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0060229	lipase activator activity(GO:0060229)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.2	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.0	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.0	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.2	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.0	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.0	0.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0030249	guanylate cyclase regulator activity(GO:0030249)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.0	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.0	GO:0032052	bile acid binding(GO:0032052)
0.0	0.0	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.8	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.4	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.3	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.0	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.7	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.5	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.4	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	1.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.0	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.0	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.0	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.2	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.1	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.2	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling