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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for PAX7_NOBOX

Z-value: 0.74

Motif logo

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Transcription factors associated with PAX7_NOBOX

Gene Symbol Gene ID Gene Info
PAX7
ENSG00000009709.7 paired box 7
NOBOX
ENSG00000106410.10 NOBOX oogenesis homeobox

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_144104551_144104702NOBOX26940.2447580.826.4e-03Click!
chr7_144113392_144113543NOBOX61470.1877730.827.1e-03Click!
chr7_144104809_144104960NOBOX24360.2604260.646.3e-02Click!
chr7_144113151_144113302NOBOX59060.1891440.636.6e-02Click!
chr7_144081989_144082140NOBOX187220.1334330.541.4e-01Click!
chr1_18957647_18957941PAX72210.9634240.836.1e-03Click!
chr1_18957463_18957614PAX7380.9872880.818.0e-03Click!
chr1_19020395_19020546PAX7624520.1342350.809.9e-03Click!
chr1_18970260_18970411PAX7123170.2857080.684.3e-02Click!
chr1_18970063_18970214PAX7121200.2862840.674.7e-02Click!

Activity of the PAX7_NOBOX motif across conditions

Conditions sorted by the z-value of the PAX7_NOBOX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_115135696_115136278 0.63 TBX3
 T-box 3
 14018
 0.21
chr20_14315841_14316127 0.59 FLRT3
 fibronectin leucine rich transmembrane protein 3
 2270
 0.36
chr1_45083000_45083241 0.58 RNF220
 ring finger protein 220
 8878
 0.17
chr5_3597777_3597928 0.55 IRX1
 iroquois homeobox 1
 1684
 0.41
chr6_56528559_56528710 0.54 DST
 dystonin
 20840
 0.27
chr3_67581837_67581988 0.52 SUCLG2
 succinate-CoA ligase, GDP-forming, beta subunit
 3266
 0.41
chr1_200865204_200865355 0.48 C1orf106
 chromosome 1 open reading frame 106
 1330
 0.42
chr2_23603304_23603524 0.46 KLHL29
 kelch-like family member 29
 4674
 0.35
chr11_131780111_131780399 0.46 NTM
 neurotrimin
 642
 0.77
chr6_125855681_125855832 0.46 RP11-735G4.1
160286
 0.04
chr4_90581488_90581639 0.44 RP11-115D19.1
21100
 0.27
chr1_159111648_159111897 0.43 AIM2
 absent in melanoma 2
 1474
 0.37
chrX_135231057_135231247 0.43 FHL1
 four and a half LIM domains 1
 415
 0.86
chr5_73839186_73839374 0.42 HEXB
 hexosaminidase B (beta polypeptide)
 96568
 0.07
chr11_69454777_69455129 0.42 CCND1
 cyclin D1
 902
 0.63
chr5_36591027_36591178 0.42 SLC1A3
 solute carrier family 1 (glial high affinity glutamate transporter), member 3
 15355
 0.27
chr1_230223080_230223231 0.41 GALNT2
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
 20137
 0.23
chr22_18575359_18575510 0.41 XXbac-B476C20.9
13784
 0.14
chr7_80377911_80378104 0.40 CD36
 CD36 molecule (thrombospondin receptor)
 75315
 0.12
chr7_70060715_70061143 0.39 AUTS2
 autism susceptibility candidate 2
 133196
 0.06
chr9_9701186_9701337 0.39 ENSG00000265735
 .
 259201
 0.02
chr13_37397601_37397752 0.39 RFXAP
 regulatory factor X-associated protein
 4315
 0.24
chr9_98188423_98189086 0.39 PTCH1
 patched 1
 54013
 0.12
chr1_1099465_1099616 0.39 ENSG00000207730
 .
 2944
 0.11
chr7_32929941_32930760 0.38 KBTBD2
 kelch repeat and BTB (POZ) domain containing 2
 415
 0.87
chr2_192176773_192176924 0.38 MYO1B
 myosin IB
 35237
 0.19
chr11_24518160_24518510 0.37 LUZP2
 leucine zipper protein 2
 389
 0.91
chr6_33589286_33590289 0.37 ITPR3
 inositol 1,4,5-trisphosphate receptor, type 3
 626
 0.65
chr4_57984994_57985389 0.37 IGFBP7
 insulin-like growth factor binding protein 7
 8640
 0.18
chr9_72745702_72745853 0.37 MAMDC2-AS1
 MAMDC2 antisense RNA 1
 17001
 0.22
chr19_13127591_13127981 0.36 CTC-239J10.1
2461
 0.15
chr6_27342407_27343330 0.36 ZNF391
 zinc finger protein 391
 13629
 0.22
chr14_74724486_74725063 0.36 VSX2
 visual system homeobox 2
 18599
 0.14
chr4_27219592_27219774 0.35 ENSG00000222206
 .
 5366
 0.35
chr11_119572371_119572522 0.35 PVRL1
 poliovirus receptor-related 1 (herpesvirus entry mediator C)
 26817
 0.16
chr2_113958350_113958501 0.35 PSD4
 pleckstrin and Sec7 domain containing 4
 4568
 0.16
chr2_163171316_163171467 0.35 IFIH1
 interferon induced with helicase C domain 1
 3803
 0.25
chr4_23975239_23975390 0.35 PPARGC1A
 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
 83614
 0.11
chr18_61555988_61556228 0.35 SERPINB2
 serpin peptidase inhibitor, clade B (ovalbumin), member 2
 1115
 0.49
chr8_59027426_59027596 0.34 FAM110B
 family with sequence similarity 110, member B
 120398
 0.07
chr13_23092547_23092698 0.34 ENSG00000253094
 .
 284662
 0.01
chr22_46929020_46929201 0.34 CELSR1
 cadherin, EGF LAG seven-pass G-type receptor 1
 2081
 0.33
chr11_37525950_37526107 0.34 ENSG00000251838
 .
 197742
 0.03
chr20_51273685_51273836 0.34 TSHZ2
 teashirt zinc finger homeobox 2
 315186
 0.01
chr10_75938020_75938413 0.34 ADK
 adenosine kinase
 1695
 0.42
chr13_110757726_110757877 0.34 ENSG00000265885
 .
 7303
 0.31
chr22_34248307_34248458 0.34 LARGE
 like-glycosyltransferase
 9230
 0.27
chr14_81789932_81790083 0.34 STON2
 stonin 2
 46730
 0.17
chr3_54897831_54897982 0.33 CACNA2D3-AS1
 CACNA2D3 antisense RNA 1
 37376
 0.21
chr4_160357796_160357947 0.33 ENSG00000251979
 .
 70309
 0.12
chr12_29716327_29716478 0.32 TMTC1
 transmembrane and tetratricopeptide repeat containing 1
 40755
 0.16
chr5_96000350_96000501 0.32 CAST
 calpastatin
 1668
 0.37
chr18_59619337_59619488 0.32 RNF152
 ring finger protein 152
 57948
 0.16
chr15_99297407_99297593 0.32 ENSG00000264480
 .
 30155
 0.19
chr7_1443631_1443991 0.32 MICALL2
 MICAL-like 2
 55151
 0.11
chr4_113331922_113332073 0.32 RP11-402J6.1
104544
 0.06
chr13_39327903_39328054 0.32 ENSG00000252795
 .
 25583
 0.19
chrX_3264180_3264467 0.32 MXRA5
 matrix-remodelling associated 5
 359
 0.92
chr15_93999319_93999470 0.32 ENSG00000212063
 .
 169842
 0.04
chr10_126315472_126315623 0.32 FAM53B-AS1
 FAM53B antisense RNA 1
 76647
 0.09
chr2_113539557_113539708 0.31 IL1A
 interleukin 1, alpha
 2535
 0.25
chr13_30415572_30415723 0.31 UBL3
 ubiquitin-like 3
 9174
 0.3
chr8_70622919_70623070 0.31 RP11-102F4.2
2631
 0.31
chr11_14375529_14375805 0.31 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
 379
 0.91
chr15_98835948_98836124 0.30 FAM169B
 family with sequence similarity 169, member B
 193171
 0.03
chr16_66851667_66851818 0.30 NAE1
 NEDD8 activating enzyme E1 subunit 1
 7140
 0.13
chr9_124846791_124846942 0.30 TTLL11
 tubulin tyrosine ligase-like family, member 11
 9019
 0.2
chr4_139635357_139635508 0.30 ENSG00000238971
 .
 97488
 0.08
chr7_100492646_100493161 0.30 ACHE
 acetylcholinesterase (Yt blood group)
 579
 0.57
chr8_112438072_112438223 0.30 ENSG00000222146
 .
 722907
 0.0
chr1_181050920_181051071 0.30 IER5
 immediate early response 5
 6643
 0.23
chr1_97033525_97033676 0.30 ENSG00000241992
 .
 15165
 0.29
chr20_1892625_1892776 0.30 SIRPA
 signal-regulatory protein alpha
 16758
 0.21
chr8_76807046_76807197 0.30 ENSG00000238595
 .
 1982
 0.49
chr11_26604890_26605185 0.30 MUC15
 mucin 15, cell surface associated
 11257
 0.3
chr5_100168975_100169126 0.30 ENSG00000221263
 .
 16781
 0.26
chr3_151034381_151034532 0.30 GPR87
 G protein-coupled receptor 87
 284
 0.9
chr9_92032170_92032321 0.29 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 1503
 0.49
chr22_19794405_19794556 0.29 C22orf29
 chromosome 22 open reading frame 29
 47859
 0.1
chrX_150695771_150695922 0.29 PASD1
 PAS domain containing 1
 36248
 0.2
chr15_101899572_101899723 0.29 PCSK6
 proprotein convertase subtilisin/kexin type 6
 6820
 0.2
chr7_121585085_121585236 0.29 PTPRZ1
 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
 71745
 0.12
chr10_6763782_6764322 0.29 PRKCQ
 protein kinase C, theta
 141789
 0.05
chr10_108111933_108112084 0.29 SORCS1
 sortilin-related VPS10 domain containing receptor 1
 259737
 0.02
chr6_41472777_41473161 0.29 RP11-328M4.2
40843
 0.13
chr3_49447935_49448923 0.29 RHOA
 ras homolog family member A
 932
 0.32
chr9_89952337_89952906 0.29 ENSG00000212421
 .
 77256
 0.11
chr15_99449448_99449599 0.29 RP11-654A16.1
12759
 0.21
chr12_56917781_56918152 0.29 RBMS2
 RNA binding motif, single stranded interacting protein 2
 2183
 0.23
chr7_98970111_98970529 0.29 ARPC1B
 actin related protein 2/3 complex, subunit 1B, 41kDa
 1552
 0.28
chr12_125179754_125179913 0.29 SCARB1
 scavenger receptor class B, member 1
 122420
 0.06
chr20_14316163_14316462 0.29 FLRT3
 fibronectin leucine rich transmembrane protein 3
 1942
 0.4
chr14_94641841_94642049 0.28 PPP4R4
 protein phosphatase 4, regulatory subunit 4
 147
 0.96
chr18_30310087_30311054 0.28 AC012123.1
 Uncharacterized protein
 39188
 0.17
chr3_79028408_79028559 0.28 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
 39211
 0.19
chr3_88191159_88191414 0.28 ZNF654
 zinc finger protein 654
 3032
 0.24
chr15_96903910_96904291 0.28 AC087477.1
 Uncharacterized protein
 387
 0.85
chr17_12569246_12569498 0.28 MYOCD
 myocardin
 66
 0.98
chr2_36589291_36589442 0.28 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 5752
 0.33
chr8_143757309_143757460 0.28 PSCA
 prostate stem cell antigen
 4490
 0.13
chr4_77067485_77067636 0.28 NUP54
 nucleoporin 54kDa
 1990
 0.3
chr9_22239467_22239618 0.28 CDKN2B-AS1
 CDKN2B antisense RNA 1
 125865
 0.06
chr17_40700695_40700889 0.28 HSD17B1
 hydroxysteroid (17-beta) dehydrogenase 1
 440
 0.63
chr8_79469123_79469274 0.28 PKIA
 protein kinase (cAMP-dependent, catalytic) inhibitor alpha
 34268
 0.19
chr15_36905175_36905326 0.28 C15orf41
 chromosome 15 open reading frame 41
 18149
 0.26
chr2_119188658_119188833 0.28 INSIG2
 insulin induced gene 2
 342695
 0.01
chr9_75771174_75771814 0.28 ANXA1
 annexin A1
 1076
 0.66
chr13_79182716_79183828 0.27 POU4F1
 POU class 4 homeobox 1
 5599
 0.19
chr6_132610665_132610816 0.27 MOXD1
 monooxygenase, DBH-like 1
 85464
 0.09
chr1_30417491_30417642 0.27 ENSG00000222787
 .
 59817
 0.17
chr13_74606153_74606483 0.27 KLF12
 Kruppel-like factor 12
 37132
 0.24
chr4_173311851_173312002 0.27 GALNTL6
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
 338330
 0.01
chr7_92254665_92254816 0.27 FAM133B
 family with sequence similarity 133, member B
 35032
 0.17
chr10_24754741_24755189 0.27 KIAA1217
 KIAA1217
 495
 0.84
chr2_36597223_36597374 0.27 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 13684
 0.29
chr3_170527527_170527678 0.27 ENSG00000222411
 .
 32359
 0.19
chr14_53275157_53275308 0.27 GNPNAT1
 glucosamine-phosphate N-acetyltransferase 1
 16846
 0.16
chr14_61445912_61446063 0.27 TRMT5
 tRNA methyltransferase 5
 1782
 0.29
chr4_184961314_184961487 0.27 STOX2
 storkhead box 2
 38922
 0.18
chr1_40471048_40471199 0.27 CAP1
 CAP, adenylate cyclase-associated protein 1 (yeast)
 34782
 0.13
chr2_196281841_196281992 0.27 ENSG00000202206
 .
 96844
 0.09
chr4_68636095_68636246 0.27 GNRHR
 gonadotropin-releasing hormone receptor
 16092
 0.17
chr15_83951840_83952048 0.27 BNC1
 basonuclin 1
 127
 0.97
chr4_77611462_77611724 0.27 AC107072.2
52817
 0.12
chr8_39259417_39259568 0.27 ENSG00000252176
 .
 158964
 0.04
chr1_246034788_246034939 0.27 RP11-83A16.1
161990
 0.04
chr10_119302142_119302346 0.27 EMX2
 empty spiracles homeobox 2
 265
 0.64
chr1_209761749_209761900 0.27 CAMK1G
 calcium/calmodulin-dependent protein kinase IG
 4750
 0.21
chr5_44235116_44235267 0.27 FGF10-AS1
 FGF10 antisense RNA 1
 153643
 0.04
chr5_140864017_140864278 0.27 PCDHGC4
 protocadherin gamma subfamily C, 4
 594
 0.53
chr9_23769338_23769489 0.27 ELAVL2
 ELAV like neuron-specific RNA binding protein 2
 9960
 0.33
chr8_31771478_31771629 0.26 NRG1-IT1
 NRG1 intronic transcript 1 (non-protein coding)
 112182
 0.07
chr10_114552786_114553214 0.26 RP11-57H14.4
30249
 0.21
chr14_55272428_55272636 0.26 SAMD4A
 sterile alpha motif domain containing 4A
 50981
 0.13
chr4_153272766_153273041 0.26 FBXW7
 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
 1220
 0.52
chr4_3387991_3388142 0.26 RGS12
 regulator of G-protein signaling 12
 5
 0.98
chr6_106972751_106973424 0.26 AIM1
 absent in melanoma 1
 13357
 0.2
chr8_62566222_62566373 0.26 ASPH
 aspartate beta-hydroxylase
 6931
 0.24
chr3_31575511_31576107 0.26 STT3B
 STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
 1527
 0.55
chr2_184434080_184434231 0.26 ENSG00000238306
 .
 380008
 0.01
chr3_100660155_100660398 0.26 ENSG00000201642
 .
 11195
 0.24
chr4_75174481_75174674 0.26 EPGN
 epithelial mitogen
 237
 0.93
chr7_139047352_139047690 0.26 C7orf55-LUC7L2
 C7orf55-LUC7L2 readthrough
 2867
 0.19
chr10_134261699_134261957 0.26 C10orf91
 chromosome 10 open reading frame 91
 3135
 0.24
chr12_95511000_95511151 0.26 FGD6
 FYVE, RhoGEF and PH domain containing 6
 326
 0.91
chr17_79315981_79316442 0.26 TMEM105
 transmembrane protein 105
 11737
 0.13
chr4_183455582_183455733 0.26 ENSG00000252343
 .
 14155
 0.26
chr3_120277024_120277175 0.26 NDUFB4
 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
 38057
 0.18
chr21_17909068_17909746 0.26 ENSG00000207638
 .
 2002
 0.33
chr3_189509857_189510008 0.26 TP63
 tumor protein p63
 2342
 0.39
chr2_21444769_21444920 0.26 TDRD15
 tudor domain containing 15
 98055
 0.09
chr16_86817661_86817812 0.25 FOXL1
 forkhead box L1
 205621
 0.02
chr3_60921693_60921844 0.25 ENSG00000212211
 .
 79491
 0.12
chr4_166361643_166362016 0.25 CPE
 carboxypeptidase E
 22451
 0.23
chr7_79953980_79954131 0.25 ENSG00000240347
 .
 6486
 0.23
chr12_125624965_125625116 0.25 AACS
 acetoacetyl-CoA synthetase
 11948
 0.29
chr14_99713575_99713726 0.25 AL109767.1
15635
 0.21
chr11_106239153_106239583 0.25 RP11-680E19.1
104326
 0.08
chr1_198250905_198251056 0.25 NEK7
 NIMA-related kinase 7
 61051
 0.16
chr2_119989374_119989591 0.25 STEAP3
 STEAP family member 3, metalloreductase
 8053
 0.2
chr5_39058731_39058980 0.25 RICTOR
 RPTOR independent companion of MTOR, complex 2
 15636
 0.24
chr12_50665639_50665877 0.25 LIMA1
 LIM domain and actin binding 1
 11509
 0.13
chr3_129383548_129383699 0.25 TMCC1
 transmembrane and coiled-coil domain family 1
 8054
 0.22
chr1_63212144_63212320 0.25 ATG4C
 autophagy related 4C, cysteine peptidase
 37574
 0.17
chr16_59637744_59637895 0.25 ENSG00000200062
 .
 63789
 0.15
chr1_3003277_3003428 0.25 PRDM16
 PR domain containing 16
 17577
 0.18
chr2_207998546_207999225 0.25 KLF7
 Kruppel-like factor 7 (ubiquitous)
 24
 0.98
chr6_64239754_64239905 0.25 PTP4A1
 protein tyrosine phosphatase type IVA, member 1
 42088
 0.17
chr5_180523773_180523999 0.25 OR2V1
 olfactory receptor, family 2, subfamily V, member 1
 28418
 0.12
chr14_52534801_52535890 0.25 NID2
 nidogen 2 (osteonidogen)
 367
 0.89
chr17_18901833_18902110 0.25 FAM83G
 family with sequence similarity 83, member G
 5518
 0.14
chr10_74436092_74436294 0.25 MCU
 mitochondrial calcium uniporter
 15696
 0.15
chr2_55810508_55810659 0.25 ENSG00000212175
 .
 17744
 0.15
chr15_67390777_67391884 0.25 SMAD3
 SMAD family member 3
 313
 0.93
chr6_117804579_117805184 0.25 DCBLD1
 discoidin, CUB and LCCL domain containing 1
 1056
 0.49
chr18_47385264_47385415 0.24 MYO5B
 myosin VB
 9123
 0.15
chr2_188418561_188419245 0.24 AC007319.1
27
 0.69
chr4_26344236_26344574 0.24 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
 357
 0.93
chr11_131170059_131170210 0.24 NTM
 neurotrimin
 70239
 0.12
chr2_95689867_95690018 0.24 MAL
 mal, T-cell differentiation protein
 1487
 0.32
chr10_29165095_29165348 0.24 ENSG00000199402
 .
 1785
 0.43
chr2_511397_511548 0.24 TMEM18
 transmembrane protein 18
 164303
 0.03
chr1_112491209_112491360 0.24 KCND3
 potassium voltage-gated channel, Shal-related subfamily, member 3
 34134
 0.17
chr22_46476561_46476775 0.24 FLJ27365
 hsa-mir-4763
 476
 0.66
chr8_87188438_87188625 0.24 CTD-3118D11.3
4116
 0.24
chr20_35830256_35830797 0.24 MROH8
 maestro heat-like repeat family member 8
 22535
 0.17
chr4_77506894_77507309 0.24 ENSG00000265314
 .
 10397
 0.17
chr7_19141522_19141673 0.24 AC003986.6
10500
 0.16
chr15_47476270_47477144 0.24 SEMA6D
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
 409
 0.87
chr14_29243474_29243665 0.24 C14orf23
 chromosome 14 open reading frame 23
 1568
 0.33
chr1_198393639_198393891 0.24 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
 116039
 0.07
chr2_149863937_149864088 0.24 LYPD6B
 LY6/PLAUR domain containing 6B
 30969
 0.22
chr7_70048822_70048973 0.24 AUTS2
 autism susceptibility candidate 2
 145228
 0.05
chr7_81040159_81040512 0.24 AC005008.2
 Uncharacterized protein
 223229
 0.02
chr13_97927308_97927620 0.24 MBNL2
 muscleblind-like splicing regulator 2
 994
 0.69
chr18_6730820_6730971 0.24 ARHGAP28
 Rho GTPase activating protein 28
 853
 0.47
chr17_69531749_69531900 0.24 ENSG00000222563
 .
 224515
 0.02
chr8_17657715_17658703 0.24 MTUS1
 microtubule associated tumor suppressor 1
 32
 0.93
chr5_158036732_158037177 0.24 CTD-2363C16.1
373060
 0.01
chr15_96878465_96878729 0.24 ENSG00000222651
 .
 2107
 0.24

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX7_NOBOX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.1 0.5 GO:0070141 response to UV-A(GO:0070141)
0.1 0.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.3 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.4 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.3 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.2 GO:0060677 ureteric bud elongation(GO:0060677)
0.1 0.3 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.1 0.3 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.3 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.1 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1 0.2 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 0.2 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.2 GO:0031223 auditory behavior(GO:0031223)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.2 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.0 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0 0.3 GO:0031579 membrane raft organization(GO:0031579)
0.0 0.1 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0061117 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.1 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.0 GO:0060462 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.4 GO:0043616 keratinocyte proliferation(GO:0043616)
0.0 0.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.5 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0032353 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0072071 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.0 GO:0035112 genitalia morphogenesis(GO:0035112)
0.0 0.1 GO:0010659 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.3 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.2 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.0 GO:0060033 Mullerian duct regression(GO:0001880) anatomical structure regression(GO:0060033)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0060438 trachea development(GO:0060438)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.1 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.0 GO:0060057 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.0 GO:0055094 response to lipoprotein particle(GO:0055094)
0.0 0.1 GO:0051446 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.0 GO:0072193 ureter development(GO:0072189) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0051963 regulation of synapse assembly(GO:0051963)
0.0 0.1 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.2 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0010894 negative regulation of steroid biosynthetic process(GO:0010894)
0.0 0.0 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0060179 male courtship behavior(GO:0008049) male mating behavior(GO:0060179)
0.0 0.0 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.0 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.3 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.0 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.1 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.0 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.2 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.0 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0090102 cochlea development(GO:0090102)
0.0 0.0 GO:0032261 purine nucleotide salvage(GO:0032261)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0047496 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.0 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 1.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:0061213 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.4 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.0 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0003097 renal water transport(GO:0003097)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.0 GO:0090493 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0008347 glial cell migration(GO:0008347)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.1 GO:0030826 regulation of cGMP biosynthetic process(GO:0030826)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0043205 fibril(GO:0043205)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.2 GO:0004104 cholinesterase activity(GO:0004104)
0.1 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.2 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.2 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0031782 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.0 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0032052 bile acid binding(GO:0032052)
0.0 0.0 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.4 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.0 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.0 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.1 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling