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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for PAX8

Z-value: 2.16

Motif logo

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Transcription factors associated with PAX8

Gene Symbol Gene ID Gene Info
PAX8
ENSG00000125618.12 paired box 8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr2_113992675_113993110PAX81280.615076-0.781.3e-02Click!
chr2_114035393_114035544PAX85030.774500-0.665.4e-02Click!
chr2_114082607_114082820PAX8461860.113986-0.608.4e-02Click!
chr2_114035017_114035267PAX88290.592173-0.521.5e-01Click!
chr2_114034526_114034677PAX813700.399257-0.481.9e-01Click!

Activity of the PAX8 motif across conditions

Conditions sorted by the z-value of the PAX8 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr16_84854349_84854509 0.86 CRISPLD2
 cysteine-rich secretory protein LCCL domain containing 2
 818
 0.61
chrX_153595297_153595831 0.81 FLNA
 filamin A, alpha
 4087
 0.1
chr4_71570546_71572213 0.81 RUFY3
 RUN and FYVE domain containing 3
 861
 0.36
chr3_71293724_71294002 0.66 FOXP1
 forkhead box P1
 453
 0.89
chr1_9882638_9884014 0.65 CLSTN1
 calsyntenin 1
 716
 0.65
chr8_9005889_9006259 0.64 PPP1R3B
 protein phosphatase 1, regulatory subunit 3B
 2132
 0.26
chr1_26238885_26239088 0.63 ENSG00000266763
 .
 746
 0.47
chr3_45685861_45686013 0.62 LIMD1-AS1
 LIMD1 antisense RNA 1
 44437
 0.11
chr2_30454378_30455881 0.62 LBH
 limb bud and heart development
 83
 0.98
chr16_85793045_85793254 0.53 C16orf74
 chromosome 16 open reading frame 74
 8414
 0.11
chr10_21462508_21463481 0.52 NEBL-AS1
 NEBL antisense RNA 1
 51
 0.59
chr8_83170405_83170556 0.51 SNX16
 sorting nexin 16
 415379
 0.01
chr7_79820122_79820273 0.50 GNAI1
 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
 3822
 0.32
chr18_51780819_51781029 0.50 POLI
 polymerase (DNA directed) iota
 14850
 0.19
chr20_17643261_17643428 0.49 RRBP1
 ribosome binding protein 1
 2192
 0.33
chr1_168440138_168440500 0.48 XCL2
 chemokine (C motif) ligand 2
 72916
 0.1
chr4_160169630_160170007 0.47 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
 18215
 0.23
chr15_44484891_44485042 0.47 FRMD5
 FERM domain containing 5
 1678
 0.47
chr16_3333511_3334475 0.47 ZNF263
 zinc finger protein 263
 38
 0.95
chr5_139525265_139525476 0.47 IGIP
 IgA-inducing protein
 19849
 0.12
chr14_100260565_100260825 0.46 EML1
 echinoderm microtubule associated protein like 1
 923
 0.67
chr12_44130303_44130454 0.45 RP11-210N13.1
2254
 0.3
chrX_9344812_9344963 0.45 TBL1X
 transducin (beta)-like 1X-linked
 86448
 0.1
chr15_81074624_81074775 0.44 KIAA1199
 KIAA1199
 2987
 0.3
chr7_26564902_26565053 0.44 KIAA0087
 KIAA0087
 13430
 0.27
chr14_90526445_90527696 0.44 KCNK13
 potassium channel, subfamily K, member 13
 1039
 0.63
chr7_94044432_94044583 0.44 COL1A2
 collagen, type I, alpha 2
 20634
 0.24
chr7_19154419_19154620 0.44 AC003986.6
2422
 0.22
chr9_134277901_134278052 0.43 PRRC2B
 proline-rich coiled-coil 2B
 8496
 0.22
chr3_115511210_115511361 0.43 ENSG00000243359
 .
 45430
 0.2
chr5_169231050_169231345 0.43 CTB-37A13.1
24828
 0.22
chr5_15510117_15510353 0.43 FBXL7
 F-box and leucine-rich repeat protein 7
 8688
 0.31
chr14_104024819_104024970 0.42 KLC1
 kinesin light chain 1
 3339
 0.09
chr11_75479321_75480435 0.42 DGAT2
 diacylglycerol O-acyltransferase 2
 21
 0.69
chr8_13371594_13371816 0.42 DLC1
 deleted in liver cancer 1
 569
 0.79
chr12_59312115_59312531 0.42 LRIG3
 leucine-rich repeats and immunoglobulin-like domains 3
 1004
 0.56
chr1_234754657_234754906 0.41 IRF2BP2
 interferon regulatory factor 2 binding protein 2
 9510
 0.19
chr1_247506079_247506341 0.41 ZNF496
 zinc finger protein 496
 11165
 0.18
chr3_8493679_8493830 0.41 LMCD1-AS1
 LMCD1 antisense RNA 1 (head to head)
 49530
 0.14
chr4_114679710_114679861 0.40 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
 2439
 0.44
chr4_146841607_146841966 0.40 ZNF827
 zinc finger protein 827
 17837
 0.22
chr1_109200139_109200290 0.39 HENMT1
 HEN1 methyltransferase homolog 1 (Arabidopsis)
 3463
 0.24
chr6_138864777_138865078 0.39 NHSL1
 NHS-like 1
 1921
 0.45
chr4_40844059_40844210 0.39 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 399
 0.83
chr16_67203881_67204335 0.39 NOL3
 nucleolar protein 3 (apoptosis repressor with CARD domain)
 51
 0.91
chr17_13965313_13965500 0.39 ENSG00000236088
 .
 7369
 0.23
chr11_84566576_84566727 0.39 DLG2
 discs, large homolog 2 (Drosophila)
 67573
 0.13
chr1_78836324_78836475 0.39 ENSG00000212308
 .
 4554
 0.3
chr21_17942611_17942934 0.39 ENSG00000207863
 .
 19785
 0.19
chr2_143828948_143829099 0.39 ARHGAP15
 Rho GTPase activating protein 15
 19908
 0.24
chr7_18832949_18833100 0.38 ENSG00000222164
 .
 14878
 0.28
chr6_144980278_144980429 0.38 UTRN
 utrophin
 627
 0.85
chr4_100777669_100777820 0.38 LAMTOR3
 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
 37789
 0.15
chr19_7744721_7744872 0.38 TRAPPC5
 trafficking protein particle complex 5
 933
 0.29
chr16_86866838_86867009 0.38 FOXL1
 forkhead box L1
 254808
 0.02
chr12_120678523_120678674 0.38 PXN
 paxillin
 9366
 0.12
chr21_28314071_28314222 0.38 ENSG00000266133
 .
 12134
 0.22
chr18_10593857_10594008 0.38 NAPG
 N-ethylmaleimide-sensitive factor attachment protein, gamma
 67523
 0.1
chr15_101611274_101611425 0.38 RP11-505E24.2
14922
 0.21
chr12_109013932_109014083 0.37 RP11-689B22.2
8456
 0.13
chr12_78336292_78336638 0.37 NAV3
 neuron navigator 3
 23591
 0.28
chr6_152700147_152700338 0.37 SYNE1-AS1
 SYNE1 antisense RNA 1
 1439
 0.39
chr15_50140285_50140436 0.37 ATP8B4
 ATPase, class I, type 8B, member 4
 28532
 0.19
chr3_13592611_13592832 0.37 FBLN2
 fibulin 2
 2040
 0.39
chr6_35187804_35187955 0.37 SCUBE3
 signal peptide, CUB domain, EGF-like 3
 5683
 0.22
chr16_86619409_86619937 0.37 FOXL1
 forkhead box L1
 7558
 0.18
chr16_51180566_51180717 0.37 AC009166.5
2509
 0.33
chr20_44098779_44099661 0.37 WFDC2
 WAP four-disulfide core domain 2
 824
 0.44
chr14_102094512_102094862 0.37 DIO3
 deiodinase, iodothyronine, type III
 66999
 0.09
chr17_643901_644052 0.37 FAM57A
 family with sequence similarity 57, member A
 7611
 0.14
chr15_76825935_76826086 0.37 ENSG00000266449
 .
 52978
 0.16
chr6_143221298_143221665 0.36 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 44857
 0.18
chr12_6937518_6938631 0.36 LEPREL2
 leprecan-like 2
 502
 0.55
chr10_103699577_103699728 0.36 ENSG00000222430
 .
 12809
 0.2
chr1_186646717_186646868 0.36 PTGS2
 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
 2767
 0.4
chr14_33532042_33532240 0.36 NPAS3
 neuronal PAS domain protein 3
 123618
 0.06
chr15_48351886_48352188 0.36 SLC24A5
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
 61132
 0.12
chr10_34827521_34827675 0.36 PARD3
 par-3 family cell polarity regulator
 111939
 0.07
chr6_2857258_2857409 0.36 ENSG00000266750
 .
 2992
 0.24
chr14_95962099_95962345 0.36 SYNE3
 spectrin repeat containing, nuclear envelope family member 3
 20049
 0.14
chr10_11645069_11645220 0.36 RP11-138I18.1
8160
 0.23
chr8_20060548_20060978 0.36 ATP6V1B2
 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
 5813
 0.2
chr4_126311427_126311944 0.36 FAT4
 FAT atypical cadherin 4
 3406
 0.33
chr3_105104777_105104928 0.35 ALCAM
 activated leukocyte cell adhesion molecule
 18665
 0.31
chr11_43945051_43945202 0.35 C11orf96
 chromosome 11 open reading frame 96
 1766
 0.25
chr21_45006172_45006433 0.35 HSF2BP
 heat shock transcription factor 2 binding protein
 71723
 0.1
chr2_242295729_242296527 0.35 FARP2
 FERM, RhoGEF and pleckstrin domain protein 2
 416
 0.79
chr11_72975754_72976333 0.35 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
 232
 0.91
chr1_180881914_180882730 0.35 KIAA1614
 KIAA1614
 3
 0.98
chr7_120630679_120630951 0.35 CPED1
 cadherin-like and PC-esterase domain containing 1
 1139
 0.51
chr8_61821706_61823076 0.34 RP11-33I11.2
100226
 0.08
chr6_36257165_36257316 0.34 PNPLA1
 patatin-like phospholipase domain containing 1
 19003
 0.17
chr17_36861833_36863162 0.34 CTB-58E17.3
17
 0.9
chr3_30124388_30124539 0.34 ENSG00000264178
 .
 55276
 0.15
chr15_59157116_59157678 0.34 RNF111
 ring finger protein 111
 23
 0.63
chr1_87858152_87858303 0.34 ENSG00000199318
 .
 60829
 0.14
chr2_20649479_20649630 0.34 RHOB
 ras homolog family member B
 2719
 0.28
chr12_50560122_50561166 0.34 CERS5
 ceramide synthase 5
 447
 0.74
chr1_54200875_54201026 0.34 GLIS1
 GLIS family zinc finger 1
 1073
 0.53
chr11_19736868_19737019 0.34 NAV2
 neuron navigator 2
 1800
 0.43
chr1_68258421_68258776 0.34 ENSG00000238778
 .
 20262
 0.19
chr4_13329866_13330017 0.34 RAB28
 RAB28, member RAS oncogene family
 53277
 0.18
chr18_55989081_55989359 0.34 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
 1332
 0.5
chr1_110282307_110283361 0.34 GSTM3
 glutathione S-transferase mu 3 (brain)
 304
 0.83
chrX_3629951_3631442 0.33 PRKX
 protein kinase, X-linked
 953
 0.63
chr15_49098304_49098486 0.33 CEP152
 centrosomal protein 152kDa
 4396
 0.19
chr6_53934757_53935103 0.33 MLIP-AS1
 MLIP antisense RNA 1
 9594
 0.22
chr6_111739256_111739407 0.33 REV3L-IT1
 REV3L intronic transcript 1 (non-protein coding)
 56521
 0.11
chr3_66350036_66350187 0.33 ENSG00000206759
 .
 6467
 0.24
chr3_31563579_31563768 0.33 STT3B
 STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
 10609
 0.3
chr16_86542600_86543872 0.33 FOXF1
 forkhead box F1
 897
 0.62
chr17_67056911_67057062 0.33 ABCA9
 ATP-binding cassette, sub-family A (ABC1), member 9
 61
 0.98
chr2_160918347_160919586 0.33 PLA2R1
 phospholipase A2 receptor 1, 180kDa
 155
 0.98
chr12_62726310_62726461 0.33 ENSG00000200814
 .
 1593
 0.43
chr1_113070155_113070306 0.33 RP4-671G15.2
9167
 0.18
chr2_182239735_182239886 0.33 ENSG00000266705
 .
 69431
 0.12
chr12_16110077_16110228 0.33 DERA
 deoxyribose-phosphate aldolase (putative)
 630
 0.8
chrX_114828631_114828846 0.33 PLS3
 plastin 3
 873
 0.64
chr1_243687933_243688084 0.32 RP11-269F20.1
20826
 0.27
chrX_117654917_117655068 0.32 DOCK11
 dedicator of cytokinesis 11
 25120
 0.21
chr7_38885898_38886049 0.32 VPS41
 vacuolar protein sorting 41 homolog (S. cerevisiae)
 15027
 0.28
chr1_9953446_9953936 0.32 CTNNBIP1
 catenin, beta interacting protein 1
 396
 0.8
chr20_49527457_49527608 0.32 ADNP
 activity-dependent neuroprotector homeobox
 1204
 0.39
chr18_34274407_34274743 0.32 FHOD3
 formin homology 2 domain containing 3
 23945
 0.22
chr15_83240603_83240843 0.32 CPEB1
 cytoplasmic polyadenylation element binding protein 1
 105
 0.95
chr1_12290222_12291451 0.32 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 712
 0.66
chr9_21081854_21082005 0.32 IFNB1
 interferon, beta 1, fibroblast
 3986
 0.21
chr1_32168571_32169014 0.32 COL16A1
 collagen, type XVI, alpha 1
 976
 0.48
chr1_46378692_46378869 0.32 MAST2
 microtubule associated serine/threonine kinase 2
 480
 0.87
chr20_33871790_33873092 0.32 EIF6
 eukaryotic translation initiation factor 6
 77
 0.88
chr15_46147938_46148235 0.32 SQRDL
 sulfide quinone reductase-like (yeast)
 173348
 0.03
chr17_56744273_56744616 0.32 ENSG00000199426
 .
 386
 0.76
chr10_78771414_78771608 0.31 KCNMA1
 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
 67771
 0.12
chr16_75600298_75601136 0.31 GABARAPL2
 GABA(A) receptor-associated protein-like 2
 221
 0.9
chr11_74041520_74041671 0.31 P4HA3
 prolyl 4-hydroxylase, alpha polypeptide III
 18893
 0.16
chr6_72595878_72596126 0.31 RIMS1
 regulating synaptic membrane exocytosis 1
 404
 0.92
chr4_127721162_127721313 0.31 ENSG00000199862
 .
 228137
 0.02
chr3_578313_578483 0.31 CHL1
 cell adhesion molecule L1-like
 147270
 0.05
chr10_63402177_63402609 0.31 C10orf107
 chromosome 10 open reading frame 107
 20326
 0.24
chr12_91487813_91488090 0.31 LUM
 lumican
 17657
 0.21
chr4_114357002_114357251 0.31 ENSG00000206820
 .
 15647
 0.2
chr14_94859853_94860004 0.31 SERPINA1
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
 2898
 0.25
chr5_159510080_159510300 0.31 PWWP2A
 PWWP domain containing 2A
 36239
 0.14
chr2_108202365_108202516 0.31 RGPD4
 RANBP2-like and GRIP domain containing 4
 240948
 0.02
chr21_29814935_29815086 0.31 ENSG00000251894
 .
 300520
 0.01
chr1_27830414_27830820 0.31 WASF2
 WAS protein family, member 2
 13948
 0.16
chr10_30574213_30574364 0.31 ENSG00000200887
 .
 14314
 0.19
chr5_135315117_135315268 0.31 LECT2
 leukocyte cell-derived chemotaxin 2
 24469
 0.18
chr2_95881225_95881376 0.31 ZNF2
 zinc finger protein 2
 49738
 0.11
chr2_40681805_40681956 0.30 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
 1302
 0.63
chr4_159093168_159093728 0.30 RP11-597D13.9
281
 0.64
chr11_65158052_65158759 0.30 FRMD8
 FERM domain containing 8
 4006
 0.13
chr10_88125313_88125533 0.30 GRID1
 glutamate receptor, ionotropic, delta 1
 812
 0.7
chr13_76362962_76363113 0.30 LMO7
 LIM domain 7
 63
 0.98
chr9_115170481_115170632 0.30 HSDL2
 hydroxysteroid dehydrogenase like 2
 28164
 0.18
chr17_77767116_77767731 0.30 CBX8
 chromobox homolog 8
 3492
 0.16
chr3_71826949_71827100 0.30 PROK2
 prokineticin 2
 7188
 0.2
chr2_157912582_157912749 0.30 ENSG00000263848
 .
 40896
 0.21
chr12_29396535_29396686 0.30 FAR2
 fatty acyl CoA reductase 2
 19932
 0.23
chr4_138787929_138788176 0.30 ENSG00000250033
 .
 190566
 0.03
chr14_73929626_73929971 0.30 ENSG00000251393
 .
 669
 0.64
chr17_1994078_1994475 0.30 RP11-667K14.5
1301
 0.3
chr6_113786265_113786416 0.30 ENSG00000222677
 .
 49849
 0.18
chr1_84630171_84630563 0.30 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
 3
 0.99
chr1_4794555_4794706 0.30 AJAP1
 adherens junctions associated protein 1
 79525
 0.12
chr3_25470358_25470509 0.30 RARB
 retinoic acid receptor, beta
 631
 0.81
chr4_166220745_166220896 0.30 MSMO1
 methylsterol monooxygenase 1
 27955
 0.16
chr20_5142036_5142305 0.30 CDS2
 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
 17298
 0.15
chr12_66290552_66290845 0.30 RP11-366L20.2
 Uncharacterized protein
 14751
 0.17
chr4_20196394_20196545 0.30 SLIT2
 slit homolog 2 (Drosophila)
 58414
 0.17
chr9_19161139_19161290 0.30 PLIN2
 perilipin 2
 11938
 0.17
chr3_32915013_32915164 0.30 TRIM71
 tripartite motif containing 71, E3 ubiquitin protein ligase
 55578
 0.13
chr19_58488964_58489115 0.30 C19orf18
 chromosome 19 open reading frame 18
 3137
 0.15
chr11_12864005_12864295 0.30 RP11-47J17.1
6192
 0.2
chr12_107631141_107631292 0.30 BTBD11
 BTB (POZ) domain containing 11
 80974
 0.1
chr1_52132272_52132423 0.29 OSBPL9
 oxysterol binding protein-like 9
 2876
 0.29
chr16_11663438_11663589 0.29 LITAF
 lipopolysaccharide-induced TNF factor
 16716
 0.17
chr19_5036988_5037627 0.29 KDM4B
 lysine (K)-specific demethylase 4B
 20971
 0.2
chr6_73905097_73905248 0.29 KHDC1P1
 KH homology domain containing 1 pseudogene 1
 14631
 0.15
chr4_62239698_62239849 0.29 LPHN3
 latrophilin 3
 123066
 0.07
chr10_124614021_124614212 0.29 CUZD1
 CUB and zona pellucida-like domains 1
 3807
 0.21
chr7_7606179_7606870 0.29 MIOS
 missing oocyte, meiosis regulator, homolog (Drosophila)
 18
 0.98
chr4_438020_438299 0.29 ENSG00000252150
 .
 23266
 0.14
chr10_24737837_24737988 0.29 KIAA1217
 KIAA1217
 450
 0.87
chr6_11581235_11581386 0.29 TMEM170B
 transmembrane protein 170B
 42799
 0.18
chr18_67507667_67507818 0.29 CD226
 CD226 molecule
 106913
 0.07
chr15_79049667_79049910 0.29 RP11-160C18.4
4332
 0.2
chr17_40157049_40157200 0.29 DNAJC7
 DnaJ (Hsp40) homolog, subfamily C, member 7
 6169
 0.12
chr2_217416160_217416311 0.29 RPL37A
 ribosomal protein L37a
 52372
 0.1
chr11_48072208_48072359 0.29 AC103828.1
34876
 0.16
chr6_144471049_144472508 0.29 STX11
 syntaxin 11
 115
 0.98
chr18_32925570_32925721 0.29 ZNF24
 zinc finger protein 24
 199
 0.95
chr4_157872609_157873145 0.29 PDGFC
 platelet derived growth factor C
 19178
 0.21
chr3_197083218_197083369 0.29 ENSG00000238491
 .
 16871
 0.2
chr15_81773129_81773280 0.28 TMC3
 transmembrane channel-like 3
 106650
 0.07
chr6_3208796_3209079 0.28 TUBB2B
 tubulin, beta 2B class IIb
 19032
 0.15
chr16_28546392_28546543 0.28 NUPR1
 nuclear protein, transcriptional regulator, 1
 3862
 0.15
chr11_128435928_128436079 0.28 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 21450
 0.21
chr19_47393595_47393746 0.28 ARHGAP35
 Rho GTPase activating protein 35
 28263
 0.14
chr4_16629429_16629735 0.28 LDB2
 LIM domain binding 2
 32084
 0.25

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.2 0.8 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.1 0.5 GO:0031394 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.5 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.1 GO:0060502 epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.1 0.5 GO:0060206 estrous cycle phase(GO:0060206)
0.1 0.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.3 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.3 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1 0.3 GO:0052033 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.1 0.2 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.1 0.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.4 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.1 0.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.2 GO:0007132 meiotic metaphase I(GO:0007132)
0.1 0.2 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.3 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.1 GO:0031223 auditory behavior(GO:0031223)
0.1 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.3 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.5 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0060536 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.1 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.2 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.2 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.2 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.1 0.1 GO:0090009 primitive streak formation(GO:0090009)
0.1 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.2 GO:0060430 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.1 0.2 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.1 GO:0060435 bronchiole development(GO:0060435)
0.1 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.1 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.3 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.2 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.2 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.0 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.1 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:2000647 negative regulation of stem cell proliferation(GO:2000647)
0.0 0.0 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.2 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0070141 response to UV-A(GO:0070141)
0.0 0.2 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0001660 fever generation(GO:0001660)
0.0 0.0 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226) positive regulation of dopamine secretion(GO:0033603)
0.0 0.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:1903054 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0032048 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 0.1 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.1 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.4 GO:0035136 forelimb morphogenesis(GO:0035136)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.0 0.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.0 GO:0050923 regulation of negative chemotaxis(GO:0050923) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0031269 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:1901021 activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.0 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.0 GO:0003207 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.1 GO:0048867 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:1902692 positive regulation of neuroblast proliferation(GO:0002052) regulation of neuroblast proliferation(GO:1902692)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.0 GO:0045064 T-helper 2 cell differentiation(GO:0045064)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.0 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.5 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.1 GO:1903393 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.1 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.1 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0002830 positive regulation of type 2 immune response(GO:0002830)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.3 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.0 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0048566 embryonic digestive tract development(GO:0048566)
0.0 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.3 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.1 GO:0032352 positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.0 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.0 GO:0010665 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0010288 response to lead ion(GO:0010288)
0.0 0.0 GO:0043049 otic placode formation(GO:0043049)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.2 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.0 GO:0045056 transcytosis(GO:0045056)
0.0 0.0 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0090197 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.0 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0009620 response to fungus(GO:0009620)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.0 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:0032823 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.0 GO:0060405 regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0 0.0 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.0 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.0 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.0 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0060840 artery development(GO:0060840)
0.0 0.0 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.2 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.0 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.0 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.0 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.0 0.0 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 1.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.0 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.0 0.0 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0019236 response to pheromone(GO:0019236)
0.0 0.0 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0052510 modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0 0.0 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.1 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0071437 invadopodium(GO:0071437)
0.1 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0000805 X chromosome(GO:0000805)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.0 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.4 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.2 GO:0043559 insulin binding(GO:0043559)
0.1 0.4 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.3 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0051378 serotonin binding(GO:0051378)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0004954 prostanoid receptor activity(GO:0004954)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.0 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.0 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.0 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.0 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 3.5 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions