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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for PBX2

Z-value: 0.59

Motif logo

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Transcription factors associated with PBX2

Gene Symbol Gene ID Gene Info
PBX2
ENSG00000204304.7 PBX homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_32158116_32158500PBX23450.7034320.752.1e-02Click!
chr6_32156796_32157600PBX27650.3835080.693.9e-02Click!
chr6_32158925_32159076PBX210370.2590740.608.5e-02Click!
chr6_32156474_32156775PBX213390.2049980.571.1e-01Click!
chr6_32158563_32158714PBX26750.4250870.462.1e-01Click!

Activity of the PBX2 motif across conditions

Conditions sorted by the z-value of the PBX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_43448588_43448818 0.33 ZFP36L2
 ZFP36 ring finger protein-like 2
 5045
 0.26
chr19_1363575_1363781 0.33 MUM1
 melanoma associated antigen (mutated) 1
 7315
 0.09
chr8_122738565_122738716 0.31 HAS2-AS1
 HAS2 antisense RNA 1
 84964
 0.1
chr11_67979557_67979856 0.27 SUV420H1
 suppressor of variegation 4-20 homolog 1 (Drosophila)
 515
 0.8
chr4_73711574_73711725 0.26 ENSG00000252955
 .
 119246
 0.06
chr1_9713633_9713784 0.25 C1orf200
 chromosome 1 open reading frame 200
 936
 0.49
chr3_105136664_105136859 0.21 ALCAM
 activated leukocyte cell adhesion molecule
 50574
 0.2
chr12_47607778_47608233 0.21 PCED1B
 PC-esterase domain containing 1B
 2047
 0.36
chr13_75899167_75899318 0.21 TBC1D4
 TBC1 domain family, member 4
 16425
 0.24
chr6_6396318_6396469 0.20 F13A1
 coagulation factor XIII, A1 polypeptide
 75147
 0.11
chr9_273424_273720 0.20 DOCK8
 dedicator of cytokinesis 8
 502
 0.5
chr10_100227423_100227662 0.20 HPS1
 Hermansky-Pudlak syndrome 1
 20859
 0.19
chr10_7227326_7227477 0.20 SFMBT2
 Scm-like with four mbt domains 2
 223306
 0.02
chr13_65531787_65531938 0.20 ENSG00000221685
 .
 906443
 0.0
chr19_1021420_1021571 0.20 ENSG00000207357
 .
 26
 0.83
chr16_11677800_11677980 0.20 LITAF
 lipopolysaccharide-induced TNF factor
 2339
 0.3
chr3_58292298_58292509 0.19 RPP14
 ribonuclease P/MRP 14kDa subunit
 366
 0.88
chr16_81481663_81481945 0.19 CMIP
 c-Maf inducing protein
 3029
 0.33
chr1_27126960_27127111 0.19 PIGV
 phosphatidylinositol glycan anchor biosynthesis, class V
 11616
 0.11
chr8_133771865_133772108 0.19 TMEM71
 transmembrane protein 71
 808
 0.63
chr2_162102268_162102419 0.17 AC009299.2
5330
 0.22
chr1_161195567_161195718 0.17 TOMM40L
 translocase of outer mitochondrial membrane 40 homolog (yeast)-like
 151
 0.85
chr11_100896662_100896813 0.17 TMEM133
 transmembrane protein 133
 33926
 0.2
chr18_43780070_43780221 0.17 C18orf25
 chromosome 18 open reading frame 25
 26145
 0.19
chr5_169074909_169075202 0.17 DOCK2
 dedicator of cytokinesis 2
 10804
 0.25
chr1_101360811_101360994 0.17 RP4-549L20.3
418
 0.45
chr1_42419485_42419636 0.16 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
 35182
 0.22
chr3_64017563_64017714 0.16 PSMD6
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
 7980
 0.12
chr19_48760988_48761397 0.16 CARD8
 caspase recruitment domain family, member 8
 1989
 0.2
chr20_62270981_62271132 0.16 CTD-3184A7.4
12453
 0.09
chr9_107687239_107687390 0.16 RP11-217B7.2
2520
 0.3
chr14_77463876_77464027 0.15 ENSG00000266553
 .
 29843
 0.15
chr8_131144625_131144776 0.15 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 13932
 0.2
chr1_88526600_88526751 0.15 ENSG00000239504
 .
 417122
 0.01
chr13_48612227_48612453 0.15 SUCLA2
 succinate-CoA ligase, ADP-forming, beta subunit
 215
 0.81
chr22_43659737_43659896 0.15 SCUBE1
 signal peptide, CUB domain, EGF-like 1
 1011
 0.5
chr11_104914640_104914826 0.15 CARD16
 caspase recruitment domain family, member 16
 1301
 0.41
chr9_117129321_117129472 0.15 AKNA
 AT-hook transcription factor
 9848
 0.2
chr18_61148002_61148153 0.14 SERPINB5
 serpin peptidase inhibitor, clade B (ovalbumin), member 5
 3717
 0.21
chr11_17300725_17300876 0.14 NUCB2
 nucleobindin 2
 2230
 0.33
chr1_198613830_198613981 0.14 PTPRC
 protein tyrosine phosphatase, receptor type, C
 5613
 0.26
chr14_101158298_101158449 0.14 DLK1
 delta-like 1 homolog (Drosophila)
 33669
 0.09
chr6_122225746_122225897 0.14 ENSG00000199932
 .
 306973
 0.01
chr13_67288038_67288189 0.14 ENSG00000238500
 .
 83205
 0.1
chr1_14028826_14029045 0.13 PRDM2
 PR domain containing 2, with ZNF domain
 2200
 0.32
chr5_179044969_179045120 0.13 HNRNPH1
 heterogeneous nuclear ribonucleoprotein H1 (H)
 0
 0.96
chr18_2573280_2573731 0.13 NDC80
 NDC80 kinetochore complex component
 1941
 0.23
chr7_7196815_7197697 0.13 C1GALT1
 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
 691
 0.7
chr18_60822617_60822842 0.13 RP11-299P2.1
4176
 0.28
chr19_44577362_44577513 0.13 ZNF284
 zinc finger protein 284
 1140
 0.28
chr17_8191755_8191938 0.13 RANGRF
 RAN guanine nucleotide release factor
 31
 0.95
chr10_89624184_89624835 0.13 KLLN
 killin, p53-regulated DNA replication inhibitor
 1315
 0.3
chr14_52000304_52000455 0.13 ENSG00000252400
 .
 10797
 0.23
chr6_100679332_100679483 0.13 RP1-121G13.2
195587
 0.03
chr17_64297348_64297511 0.13 PRKCA
 protein kinase C, alpha
 1515
 0.42
chr15_77288409_77288609 0.13 PSTPIP1
 proline-serine-threonine phosphatase interacting protein 1
 594
 0.75
chr9_88357119_88357540 0.12 AGTPBP1
 ATP/GTP binding protein 1
 385
 0.93
chr21_15917471_15917848 0.12 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
 1003
 0.63
chr2_174518145_174518296 0.12 CDCA7
 cell division cycle associated 7
 298620
 0.01
chr8_56831921_56832112 0.12 ENSG00000216204
 .
 10496
 0.14
chr1_176965552_176965703 0.12 ENSG00000202609
 .
 32954
 0.24
chr17_71641526_71641788 0.12 SDK2
 sidekick cell adhesion molecule 2
 1429
 0.46
chr3_147337841_147337992 0.12 ZIC1
 Zic family member 1
 210745
 0.02
chr20_47441910_47442200 0.12 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 2365
 0.4
chr8_82597903_82598285 0.12 IMPA1
 inositol(myo)-1(or 4)-monophosphatase 1
 27
 0.97
chr1_161035238_161035389 0.12 AL591806.1
 Uncharacterized protein
 342
 0.73
chr13_107220642_107220857 0.12 ARGLU1
 arginine and glutamate rich 1
 237
 0.95
chr1_90223723_90223893 0.12 ENSG00000239176
 .
 10069
 0.21
chrX_119737518_119737925 0.12 MCTS1
 malignant T cell amplified sequence 1
 114
 0.97
chr12_65927555_65927706 0.12 MSRB3
 methionine sulfoxide reductase B3
 206975
 0.02
chr13_106828579_106828730 0.12 ENSG00000222682
 .
 20815
 0.25
chr15_74834439_74834753 0.12 ARID3B
 AT rich interactive domain 3B (BRIGHT-like)
 1078
 0.48
chr4_47035027_47035178 0.11 GABRB1
 gamma-aminobutyric acid (GABA) A receptor, beta 1
 1452
 0.52
chr9_80644809_80645465 0.11 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 383
 0.92
chr2_43242041_43242199 0.11 ENSG00000207087
 .
 76512
 0.11
chr11_3010488_3011464 0.11 AC131971.1
 HCG1782999; PRO0943; Uncharacterized protein
 117
 0.83
chr3_46142263_46142414 0.11 CCR3
 chemokine (C-C motif) receptor 3
 62758
 0.1
chr2_71677518_71677669 0.11 DYSF
 dysferlin
 3259
 0.3
chr3_112693608_112694254 0.11 CD200R1
 CD200 receptor 1
 6
 0.97
chr12_40077019_40077550 0.11 C12orf40
 chromosome 12 open reading frame 40
 57299
 0.13
chr8_124186554_124186705 0.11 FAM83A
 family with sequence similarity 83, member A
 4658
 0.13
chr14_98668445_98668596 0.11 ENSG00000222066
 .
 129567
 0.06
chr12_69419070_69419221 0.11 CPM
 carboxypeptidase M
 62096
 0.11
chr17_7744594_7744818 0.11 KDM6B
 lysine (K)-specific demethylase 6B
 1426
 0.25
chr19_8645059_8645210 0.11 AC130469.2
910
 0.44
chr2_163173016_163173250 0.11 IFIH1
 interferon induced with helicase C domain 1
 2061
 0.31
chr8_2590819_2591169 0.11 MYOM2
 myomesin 2
 597810
 0.0
chr12_96427792_96427943 0.11 LTA4H
 leukotriene A4 hydrolase
 1572
 0.33
chr4_159689303_159689454 0.11 FNIP2
 folliculin interacting protein 2
 912
 0.58
chr11_102192518_102192994 0.11 BIRC3
 baculoviral IAP repeat containing 3
 3196
 0.22
chr16_85096756_85096907 0.10 KIAA0513
 KIAA0513
 13
 0.98
chr6_11094574_11095155 0.10 SMIM13
 small integral membrane protein 13
 598
 0.69
chr11_30606067_30606222 0.10 RP5-1024C24.1
434
 0.82
chr6_6604888_6605039 0.10 LY86
 lymphocyte antigen 86
 16061
 0.23
chr1_116197547_116197911 0.10 VANGL1
 VANGL planar cell polarity protein 1
 3706
 0.26
chr7_69061838_69061989 0.10 AUTS2
 autism susceptibility candidate 2
 1992
 0.44
chr18_60984369_60984520 0.10 BCL2
 B-cell CLL/lymphoma 2
 1601
 0.34
chr8_124049779_124050367 0.10 TBC1D31
 TBC1 domain family, member 31
 4135
 0.17
chr2_225876272_225876423 0.10 ENSG00000263828
 .
 1090
 0.63
chr13_114439745_114439896 0.10 TMEM255B
 transmembrane protein 255B
 22396
 0.21
chr6_24934559_24934719 0.10 FAM65B
 family with sequence similarity 65, member B
 1549
 0.46
chr16_23159267_23159418 0.10 USP31
 ubiquitin specific peptidase 31
 1249
 0.52
chr17_28087229_28087445 0.10 RP11-82O19.1
784
 0.6
chr1_8482394_8483668 0.10 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 695
 0.63
chr2_204732928_204733209 0.10 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
 402
 0.9
chr8_21763339_21763611 0.10 DOK2
 docking protein 2, 56kDa
 7699
 0.2
chr18_57568186_57568738 0.10 PMAIP1
 phorbol-12-myristate-13-acetate-induced protein 1
 1214
 0.58
chr1_89591012_89591781 0.10 GBP2
 guanylate binding protein 2, interferon-inducible
 401
 0.85
chr7_72705892_72706043 0.10 GTF2IRD2P1
 GTF2I repeat domain containing 2 pseudogene 1
 11824
 0.13
chr15_71006763_71006990 0.10 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 11262
 0.26
chr6_5997225_5997376 0.10 NRN1
 neuritin 1
 9900
 0.25
chr2_137926013_137926164 0.10 THSD7B
 thrombospondin, type I, domain containing 7B
 111814
 0.08
chr7_75057272_75057423 0.10 NSUN5P1
 NOP2/Sun domain family, member 5 pseudogene 1
 12165
 0.11
chr17_79361447_79361695 0.09 RP11-1055B8.6
 Uncharacterized protein
 7704
 0.12
chr13_41588793_41589349 0.09 ELF1
 E74-like factor 1 (ets domain transcription factor)
 4379
 0.23
chr2_27255514_27255731 0.09 TMEM214
 transmembrane protein 214
 200
 0.85
chr9_27454069_27454220 0.09 RP11-298E2.2
62412
 0.11
chr8_16870402_16870553 0.09 FGF20
 fibroblast growth factor 20
 10787
 0.23
chrX_77361758_77362293 0.09 PGK1
 phosphoglycerate kinase 1
 166
 0.97
chr3_71834842_71834993 0.09 PROK2
 prokineticin 2
 560
 0.77
chr20_35830256_35830797 0.09 MROH8
 maestro heat-like repeat family member 8
 22535
 0.17
chr2_106367063_106367214 0.09 NCK2
 NCK adaptor protein 2
 4950
 0.33
chr20_52295216_52295367 0.09 ENSG00000238468
 .
 9994
 0.25
chr7_16794353_16794513 0.09 TSPAN13
 tetraspanin 13
 1273
 0.44
chr1_207093221_207093431 0.09 FAIM3
 Fas apoptotic inhibitory molecule 3
 1886
 0.27
chr3_151914442_151914993 0.09 MBNL1
 muscleblind-like splicing regulator 1
 71112
 0.11
chr4_154389972_154390290 0.09 KIAA0922
 KIAA0922
 2630
 0.35
chrX_70585572_70585765 0.09 TAF1
 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
 446
 0.84
chr13_100630096_100630247 0.09 ZIC2
 Zic family member 2
 3855
 0.22
chr16_89034372_89034523 0.09 CBFA2T3
 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
 8954
 0.15
chr2_5727897_5728048 0.09 AC108025.2
103206
 0.07
chrX_3189331_3189985 0.09 CXorf28
 chromosome X open reading frame 28
 203
 0.96
chr14_55137368_55137519 0.09 SAMD4A
 sterile alpha motif domain containing 4A
 84108
 0.09
chr13_46038649_46038966 0.09 COG3
 component of oligomeric golgi complex 3
 253
 0.93
chr13_37575523_37575689 0.09 EXOSC8
 exosome component 8
 928
 0.49
chr3_188152189_188152340 0.09 LPP-AS1
 LPP antisense RNA 1
 134190
 0.05
chr4_40209794_40209945 0.09 RHOH
 ras homolog family member H
 7905
 0.22
chr20_23400882_23401206 0.09 NAPB
 N-ethylmaleimide-sensitive factor attachment protein, beta
 1054
 0.39
chr1_247123081_247123305 0.09 AHCTF1
 AT hook containing transcription factor 1
 27913
 0.17
chr20_61408872_61409023 0.09 LINC00659
 long intergenic non-protein coding RNA 659
 2183
 0.2
chr1_40848541_40848692 0.09 SMAP2
 small ArfGAP2
 8296
 0.18
chr15_93445330_93445481 0.09 CHD2
 chromodomain helicase DNA binding protein 2
 1840
 0.31
chr13_100622367_100622591 0.09 ZIC5
 Zic family member 5
 1684
 0.37
chr6_77599653_77599804 0.09 ENSG00000272445
 .
 332257
 0.01
chr5_95155170_95155321 0.09 GLRX
 glutaredoxin (thioltransferase)
 3170
 0.2
chr6_152505186_152505339 0.09 SYNE1
 spectrin repeat containing, nuclear envelope 1
 15763
 0.29
chr6_31514651_31514955 0.09 NFKBIL1
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
 156
 0.49
chr1_145396978_145397482 0.08 ENSG00000201558
 .
 14473
 0.13
chr3_89033455_89033606 0.08 EPHA3
 EPH receptor A3
 123144
 0.07
chr5_110560941_110561277 0.08 CAMK4
 calcium/calmodulin-dependent protein kinase IV
 1325
 0.51
chr2_231082753_231082904 0.08 SP110
 SP110 nuclear body protein
 1789
 0.35
chr4_84036093_84036262 0.08 PLAC8
 placenta-specific 8
 222
 0.95
chrX_14515159_14515412 0.08 GLRA2
 glycine receptor, alpha 2
 32135
 0.25
chr9_111063457_111063608 0.08 ENSG00000222512
 .
 57677
 0.17
chr11_66883336_66883487 0.08 KDM2A
 lysine (K)-specific demethylase 2A
 3329
 0.22
chr10_22630594_22630745 0.08 SPAG6
 sperm associated antigen 6
 3730
 0.19
chr3_112217855_112218341 0.08 BTLA
 B and T lymphocyte associated
 107
 0.98
chr4_108910417_108910832 0.08 HADH
 hydroxyacyl-CoA dehydrogenase
 246
 0.92
chr17_72463483_72463716 0.08 CD300A
 CD300a molecule
 598
 0.68
chr19_18668411_18668562 0.08 KXD1
 KxDL motif containing 1
 86
 0.92
chr12_67662728_67662890 0.08 CAND1
 cullin-associated and neddylation-dissociated 1
 252
 0.96
chr6_138192975_138193775 0.08 RP11-356I2.4
4005
 0.25
chr2_86116312_86117036 0.08 ST3GAL5
 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
 537
 0.8
chr1_153643822_153644080 0.08 ILF2
 interleukin enhancer binding factor 2
 427
 0.65
chr8_31158022_31158173 0.08 RP11-363L24.3
123414
 0.06
chr17_27919309_27919602 0.08 RP11-68I3.7
196
 0.81
chr2_192014463_192014614 0.08 STAT4
 signal transducer and activator of transcription 4
 1159
 0.54
chr3_16550538_16550689 0.08 RFTN1
 raftlin, lipid raft linker 1
 3798
 0.32
chr3_101442973_101443124 0.08 CEP97
 centrosomal protein 97kDa
 279
 0.88
chr6_119027020_119027704 0.08 CEP85L
 centrosomal protein 85kDa-like
 3869
 0.35
chr11_61780107_61780258 0.08 AP003733.1
 Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
 44729
 0.1
chr4_109062684_109062835 0.08 LEF1
 lymphoid enhancer-binding factor 1
 24698
 0.2
chr2_68963544_68963853 0.08 ARHGAP25
 Rho GTPase activating protein 25
 1684
 0.46
chr17_38177630_38177781 0.07 MED24
 mediator complex subunit 24
 1708
 0.23
chr4_143321559_143321710 0.07 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 30778
 0.27
chr14_78081630_78082591 0.07 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
 1006
 0.56
chr2_144006550_144006740 0.07 RP11-190J23.1
76904
 0.11
chr9_132402475_132402626 0.07 RP11-483H20.4
205
 0.89
chr1_24882080_24882472 0.07 NCMAP
 noncompact myelin associated protein
 326
 0.88
chr8_116601507_116601658 0.07 TRPS1
 trichorhinophalangeal syndrome I
 30715
 0.24
chr5_90677845_90678028 0.07 ARRDC3
 arrestin domain containing 3
 1240
 0.57
chr3_107806842_107807168 0.07 CD47
 CD47 molecule
 2856
 0.4
chr4_47913848_47913999 0.07 NFXL1
 nuclear transcription factor, X-box binding-like 1
 2633
 0.29
chr19_24155336_24155487 0.07 CTB-92J24.3
14679
 0.18
chr8_8570882_8571033 0.07 CLDN23
 claudin 23
 11509
 0.26
chr7_104643472_104643623 0.07 LINC01004
 long intergenic non-protein coding RNA 1004
 9924
 0.16
chr10_15211985_15212371 0.07 NMT2
 N-myristoyltransferase 2
 1486
 0.45
chr9_139434770_139435052 0.07 RP11-413M3.4
2422
 0.15
chr12_9903729_9904030 0.07 CD69
 CD69 molecule
 9618
 0.15
chr10_7451836_7452578 0.07 SFMBT2
 Scm-like with four mbt domains 2
 904
 0.71
chr2_11893696_11894011 0.07 LPIN1
 lipin 1
 7089
 0.15
chr3_177321275_177321426 0.07 ENSG00000200288
 .
 20847
 0.27
chr18_27836555_27836706 0.07 ENSG00000251702
 .
 727442
 0.0
chr4_153600093_153601094 0.07 TMEM154
 transmembrane protein 154
 571
 0.78
chr4_152588470_152588621 0.07 RP11-164P12.4
169
 0.96
chr1_149969239_149969390 0.07 OTUD7B
 OTU domain containing 7B
 13310
 0.14
chr17_46646140_46646364 0.07 HOXB3
 homeobox B3
 5133
 0.08
chr4_37075132_37075283 0.07 ENSG00000264319
 .
 168406
 0.04
chr2_208395832_208396657 0.07 CREB1
 cAMP responsive element binding protein 1
 1416
 0.37
chr3_187637243_187637630 0.07 BCL6
 B-cell CLL/lymphoma 6
 173921
 0.03

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.2 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.2 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.0 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0003352 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.0 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.0 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.0 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes