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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PBX3

Z-value: 1.16

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Transcription factors associated with PBX3

Gene Symbol	Gene ID	Gene Info
PBX3 Ensembl NCBI GeneCards UniProt	ENSG00000167081.12	PBX3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
PBX3	chr9_128514663_128514814	4260	0.307116	-0.93	2.8e-04	Click!
PBX3	chr9_128664438_128664589	36963	0.227213	-0.92	5.2e-04	Click!
PBX3	chr9_128524004_128524155	13601	0.262021	-0.91	7.2e-04	Click!
PBX3	chr9_128516456_128516607	6053	0.285353	-0.88	1.9e-03	Click!
PBX3	chr9_128512019_128512257	1660	0.479975	-0.87	2.6e-03	Click!

Activity of the PBX3 motif across conditions

Conditions sorted by the z-value of the PBX3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_46612034_46612360	0.94	SLC38A1	solute carrier family 38, member 1	49287	0.18
chr22_40298890_40299260	0.83	GRAP2	GRB2-related adaptor protein 2	1962	0.3
chr7_150148386_150148563	0.76	GIMAP8	GTPase, IMAP family member 8	756	0.63
chrX_135731409_135731662	0.72	CD40LG	CD40 ligand	1149	0.47
chr13_24827167_24827318	0.72	SPATA13-AS1	SPATA13 antisense RNA 1	1335	0.33
chr9_130539941_130540132	0.71	SH2D3C	SH2 domain containing 3C	984	0.33
chr1_154927193_154927621	0.70	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	1173	0.25
chr5_35859258_35859647	0.69	IL7R	interleukin 7 receptor	2458	0.3
chr12_55362139_55362302	0.68	TESPA1	thymocyte expressed, positive selection associated 1	5118	0.26
chr14_91866311_91866542	0.68	CCDC88C	coiled-coil domain containing 88C	17264	0.22
chr6_149805654_149805958	0.65	ZC3H12D	zinc finger CCCH-type containing 12D	320	0.87
chr1_156785806_156786457	0.64	SH2D2A	SH2 domain containing 2A	495	0.51
chr19_39825870_39826313	0.64	GMFG	glia maturation factor, gamma	554	0.58
chr16_21519015_21519166	0.62	ENSG00000265462	.	1634	0.33
chr20_52199257_52199767	0.62	ZNF217	zinc finger protein 217	124	0.96
chr17_75663137_75663644	0.62	SEPT9	septin 9	185395	0.03
chr14_22969065_22969423	0.61	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	13073	0.1
chr1_239883177_239883989	0.60	CHRM3	cholinergic receptor, muscarinic 3	740	0.59
chr21_15917916_15918619	0.59	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	395	0.89
chr17_76128814_76128979	0.58	TMC6	transmembrane channel-like 6	408	0.73
chr14_22974481_22974956	0.57	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	18547	0.09
chr10_129861850_129862130	0.56	PTPRE	protein tyrosine phosphatase, receptor type, E	16156	0.26
chr5_177236761_177236962	0.56	FAM153A	family with sequence similarity 153, member A	26462	0.14
chr6_159464766_159465080	0.56	TAGAP	T-cell activation RhoGTPase activating protein	1127	0.51
chr13_99910339_99910626	0.56	GPR18	G protein-coupled receptor 18	146	0.96
chr15_55547653_55548107	0.56	RAB27A	RAB27A, member RAS oncogene family	6647	0.22
chr18_13383462_13383613	0.56	LDLRAD4	low density lipoprotein receptor class A domain containing 4	984	0.5
chr11_102192518_102192994	0.55	BIRC3	baculoviral IAP repeat containing 3	3196	0.22
chr5_175461188_175461339	0.55	THOC3	THO complex 3	420	0.79
chr2_204801338_204802214	0.55	ICOS	inducible T-cell co-stimulator	273	0.95
chr11_46354220_46354463	0.55	DGKZ	diacylglycerol kinase, zeta	114	0.96
chr22_50631230_50631436	0.54	TRABD	TraB domain containing	110	0.82
chr16_81748402_81748687	0.54	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	24158	0.24
chr2_235362717_235362976	0.52	ARL4C	ADP-ribosylation factor-like 4C	42398	0.22
chr6_35279100_35279566	0.50	DEF6	differentially expressed in FDCP 6 homolog (mouse)	1818	0.34
chr22_40781561_40781851	0.50	RP5-1042K10.10		2515	0.24
chr14_22471633_22471925	0.49	ENSG00000238634	.	139108	0.04
chr11_65379543_65379824	0.49	MAP3K11	mitogen-activated protein kinase kinase kinase 11	911	0.31
chr9_36142717_36143534	0.48	GLIPR2	GLI pathogenesis-related 2	6383	0.2
chr1_117342787_117343202	0.48	CD2	CD2 molecule	45905	0.14
chr2_182174449_182174635	0.48	ENSG00000266705	.	4163	0.36
chr11_121329971_121330303	0.48	RP11-730K11.1		6415	0.25
chr19_16479476_16479627	0.48	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	6787	0.16
chr19_18414393_18414628	0.47	LSM4	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)	12559	0.09
chr5_35859676_35859963	0.47	IL7R	interleukin 7 receptor	2825	0.28
chr1_169665907_169666062	0.47	SELL	selectin L	14855	0.19
chr11_118213949_118214100	0.47	CD3D	CD3d molecule, delta (CD3-TCR complex)	565	0.54
chr2_206809495_206809646	0.47	ENSG00000201875	.	44216	0.13
chr14_91707602_91707801	0.46	CTD-2547L24.3	HCG1816139; Uncharacterized protein	1402	0.37
chrX_44203680_44203969	0.46	EFHC2	EF-hand domain (C-terminal) containing 2	906	0.71
chr11_2323777_2324127	0.45	TSPAN32	tetraspanin 32	1	0.92
chr17_28033493_28033909	0.44	RP11-82O19.1		54420	0.07
chr1_21620200_21620457	0.44	RP5-1071N3.1		545	0.47
chr13_31311093_31311268	0.44	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	1535	0.52
chr7_5572395_5572659	0.44	ACTB	actin, beta	2187	0.2
chr5_100116307_100116504	0.43	ENSG00000221263	.	35864	0.2
chr6_119131761_119131953	0.43	MCM9	minichromosome maintenance complex component 9	18559	0.24
chr14_22895521_22895672	0.43	ENSG00000251002	.	6123	0.13
chr21_46337373_46337524	0.43	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3250	0.13
chr11_64216918_64217087	0.42	AP003774.4	HCG1652096, isoform CRA_a; Uncharacterized protein; cDNA FLJ37045 fis, clone BRACE2012185	456	0.79
chr10_8446299_8446474	0.42	ENSG00000212505	.	252408	0.02
chr17_4389201_4389708	0.41	RP13-580F15.2		194	0.92
chr4_40203939_40204397	0.41	RHOH	ras homolog family member H	2204	0.34
chr16_11677800_11677980	0.41	LITAF	lipopolysaccharide-induced TNF factor	2339	0.3
chr16_30486681_30486832	0.41	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	1434	0.16
chr1_207088744_207089040	0.41	FAIM3	Fas apoptotic inhibitory molecule 3	6320	0.15
chr1_19804030_19804234	0.41	CAPZB	capping protein (actin filament) muscle Z-line, beta	6447	0.18
chr12_55375935_55376187	0.41	TESPA1	thymocyte expressed, positive selection associated 1	439	0.86
chr14_91834289_91834440	0.41	ENSG00000265856	.	34307	0.17
chr16_68113033_68113320	0.41	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	6071	0.11
chr13_99960008_99960188	0.40	GPR183	G protein-coupled receptor 183	439	0.84
chr1_145454503_145454819	0.40	TXNIP	thioredoxin interacting protein	15355	0.1
chr2_69867626_69867777	0.39	AAK1	AP2 associated kinase 1	3085	0.28
chr11_118094529_118095128	0.39	AMICA1	adhesion molecule, interacts with CXADR antigen 1	26	0.97
chr10_70849708_70849969	0.39	SRGN	serglycin	1964	0.33
chr1_19803053_19803337	0.39	CAPZB	capping protein (actin filament) muscle Z-line, beta	7384	0.17
chr4_90227728_90227903	0.39	GPRIN3	GPRIN family member 3	1346	0.6
chr17_143001_143152	0.39	RP11-1260E13.1		28107	0.13
chr5_39200999_39201150	0.38	FYB	FYN binding protein	2055	0.44
chr14_22865587_22865738	0.38	ENSG00000251002	.	36057	0.11
chr1_111742376_111742661	0.38	DENND2D	DENN/MADD domain containing 2D	793	0.38
chr16_85936780_85936931	0.38	IRF8	interferon regulatory factor 8	411	0.88
chr10_5336313_5336469	0.38	AKR1C7P	aldo-keto reductase family 1, member C7, pseudogene	5958	0.22
chr17_56421423_56421650	0.38	BZRAP1-AS1	BZRAP1 antisense RNA 1	6817	0.11
chr14_22964891_22965136	0.37	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	8842	0.1
chr7_99819175_99819326	0.37	ENSG00000222482	.	1507	0.2
chr5_156698426_156698828	0.37	CYFIP2	cytoplasmic FMR1 interacting protein 2	2265	0.23
chr5_39203555_39203988	0.37	FYB	FYN binding protein	642	0.81
chr22_39547258_39547409	0.37	CBX7	chromobox homolog 7	1116	0.46
chr3_185826921_185827162	0.36	ETV5	ets variant 5	140	0.97
chr21_44166870_44167151	0.36	AP001627.1		5142	0.26
chr4_2799841_2800188	0.36	SH3BP2	SH3-domain binding protein 2	277	0.92
chr11_35194712_35194909	0.36	CD44	CD44 molecule (Indian blood group)	3308	0.21
chrX_48793999_48794379	0.36	PIM2	pim-2 oncogene	17888	0.08
chr19_14477270_14477421	0.36	CD97	CD97 molecule	14623	0.15
chr5_66461571_66461722	0.36	MAST4	microtubule associated serine/threonine kinase family member 4	23384	0.22
chr10_82220206_82220414	0.35	TSPAN14	tetraspanin 14	1252	0.5
chr1_1136100_1136251	0.35	TNFRSF18	tumor necrosis factor receptor superfamily, member 18	4885	0.08
chr2_96986640_96986853	0.35	AC021188.4		723	0.57
chr2_197032904_197033284	0.35	STK17B	serine/threonine kinase 17b	2630	0.28
chr18_9107105_9107411	0.35	NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	3178	0.21
chr22_22089210_22089361	0.34	YPEL1	yippee-like 1 (Drosophila)	759	0.55
chr19_22605163_22605314	0.34	ZNF98	zinc finger protein 98	79	0.98
chr15_63798708_63798859	0.34	USP3	ubiquitin specific peptidase 3	1928	0.4
chr2_240302618_240303103	0.34	HDAC4	histone deacetylase 4	19783	0.17
chr14_99710276_99710624	0.34	AL109767.1		18835	0.2
chr19_12512149_12512361	0.34	ZNF799	zinc finger protein 799	170	0.92
chr3_30670169_30670603	0.34	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	22293	0.26
chr16_27413508_27414237	0.34	IL21R	interleukin 21 receptor	377	0.88
chrX_71321072_71321371	0.34	RGAG4	retrotransposon gag domain containing 4	30457	0.14
chr5_137416910_137417200	0.34	WNT8A	wingless-type MMTV integration site family, member 8A	2526	0.17
chr17_33541971_33542122	0.34	SLC35G3	solute carrier family 35, member G3	20634	0.11
chr2_74432517_74432668	0.34	MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	6849	0.14
chr14_106950202_106950486	0.34	IGHVII-44-2	immunoglobulin heavy variable (II)-44-2 (pseudogene)	53	0.89
chr8_91018652_91018803	0.34	DECR1	2,4-dienoyl CoA reductase 1, mitochondrial	4982	0.24
chr13_99856162_99856313	0.34	ENSG00000201793	.	1725	0.34
chr1_204941075_204941226	0.33	NFASC	neurofascin	9834	0.21
chr12_66662591_66662742	0.33	RP11-335I12.2		11452	0.15
chr2_27485345_27486489	0.33	SLC30A3	solute carrier family 30 (zinc transporter), member 3	178	0.89
chr9_82185992_82186420	0.33	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	482	0.9
chr14_75715883_75716034	0.33	RP11-293M10.2		10156	0.15
chr7_50345819_50346403	0.33	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1733	0.5
chr16_23846602_23847146	0.33	PRKCB	protein kinase C, beta	448	0.87
chr1_111423669_111423843	0.33	CD53	CD53 molecule	7980	0.2
chr17_43487096_43487739	0.33	ARHGAP27	Rho GTPase activating protein 27	335	0.82
chr7_21467616_21467934	0.33	SP4	Sp4 transcription factor	114	0.97
chr6_126153129_126153280	0.33	NCOA7-AS1	NCOA7 antisense RNA 1	13200	0.18
chr16_84582402_84582610	0.33	TLDC1	TBC/LysM-associated domain containing 1	5133	0.21
chr1_168390803_168391087	0.32	ENSG00000207974	.	46183	0.16
chr12_48551760_48551911	0.32	ASB8	ankyrin repeat and SOCS box containing 8	457	0.75
chr19_6926549_6926700	0.32	RP11-1137G4.3		26598	0.12
chr16_3116517_3116777	0.32	IL32	interleukin 32	834	0.3
chr12_57441357_57441508	0.32	MYO1A	myosin IA	182	0.9
chr22_17567910_17568443	0.32	IL17RA	interleukin 17 receptor A	2327	0.26
chr2_128395227_128395389	0.32	LIMS2	LIM and senescent cell antigen-like domains 2	4398	0.16
chr6_166954866_166955076	0.32	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	967	0.56
chr4_6928559_6928859	0.31	TBC1D14	TBC1 domain family, member 14	16734	0.16
chr1_26158794_26158945	0.31	RP1-317E23.7		244	0.84
chr1_84902979_84903163	0.31	DNASE2B	deoxyribonuclease II beta	29158	0.16
chr6_159074554_159074705	0.31	SYTL3	synaptotagmin-like 3	3583	0.22
chr17_45297902_45298194	0.31	ENSG00000252088	.	40	0.92
chr11_128566078_128566229	0.31	SENCR	smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA	235	0.91
chr2_198651086_198651566	0.31	BOLL	boule-like RNA-binding protein	28	0.98
chr9_117152254_117152405	0.31	AKNA	AT-hook transcription factor	1968	0.35
chr14_100533458_100533776	0.31	EVL	Enah/Vasp-like	843	0.55
chr15_74834439_74834753	0.31	ARID3B	AT rich interactive domain 3B (BRIGHT-like)	1078	0.48
chr16_68403596_68403824	0.30	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	1198	0.37
chr17_75606628_75606867	0.30	SEPT9	septin 9	128752	0.05
chr19_42703347_42703984	0.30	ENSG00000265122	.	6435	0.1
chr19_3036283_3036702	0.30	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	6880	0.13
chr17_43305439_43305590	0.30	CTD-2020K17.1		5925	0.1
chr4_184642687_184643147	0.30	ENSG00000251739	.	15833	0.17
chr18_24289152_24289303	0.30	ENSG00000265369	.	19734	0.21
chr7_50351765_50352753	0.30	IKZF1	IKAROS family zinc finger 1 (Ikaros)	3941	0.34
chrX_64917369_64917808	0.30	MSN	moesin	30051	0.25
chr6_135450306_135450457	0.30	HBS1L	HBS1-like (S. cerevisiae)	26187	0.17
chr5_39207439_39207590	0.30	FYB	FYN binding protein	4385	0.32
chr9_95945997_95946357	0.30	WNK2	WNK lysine deficient protein kinase 2	1021	0.58
chr10_126182799_126183006	0.29	LHPP	phospholysine phosphohistidine inorganic pyrophosphate phosphatase	32490	0.16
chr2_106572142_106572293	0.29	AC009505.2		98584	0.07
chr17_43302789_43303077	0.29	CTD-2020K17.1		3344	0.12
chr17_17654361_17654512	0.29	RAI1-AS1	RAI1 antisense RNA 1	19699	0.13
chrX_19815653_19816006	0.29	SH3KBP1	SH3-domain kinase binding protein 1	2040	0.46
chr1_156933589_156933740	0.29	ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	14858	0.14
chr1_231113171_231113322	0.29	TTC13	tetratricopeptide repeat domain 13	1296	0.3
chr14_20811572_20811723	0.29	RPPH1	ribonuclease P RNA component H1	81	0.5
chr6_2222017_2222664	0.29	GMDS	GDP-mannose 4,6-dehydratase	23586	0.28
chr16_1585013_1585440	0.29	TMEM204	transmembrane protein 204	1652	0.19
chrX_153267742_153268222	0.29	IRAK1	interleukin-1 receptor-associated kinase 1	11715	0.09
chr1_120642387_120642538	0.29	ENSG00000207149	.	27100	0.19
chr21_45579276_45579734	0.28	AP001055.1		14075	0.13
chr6_111180428_111180655	0.28	ENSG00000199360	.	2921	0.21
chr19_22193781_22193932	0.28	ZNF208	zinc finger protein 208	105	0.98
chr2_98279402_98280293	0.28	ACTR1B	ARP1 actin-related protein 1 homolog B, centractin beta (yeast)	723	0.38
chr1_89664664_89664873	0.28	GBP4	guanylate binding protein 4	153	0.96
chr22_42831151_42831302	0.28	NFAM1	NFAT activating protein with ITAM motif 1	2825	0.27
chr6_160241186_160241397	0.28	PNLDC1	poly(A)-specific ribonuclease (PARN)-like domain containing 1	19985	0.12
chr8_24151584_24151953	0.28	ADAM28	ADAM metallopeptidase domain 28	144	0.97
chr2_45168726_45169073	0.28	SIX3	SIX homeobox 3	3	0.61
chr1_207997626_207997777	0.28	ENSG00000203709	.	21833	0.22
chr17_72459271_72459541	0.28	CD300A	CD300a molecule	3149	0.19
chr1_160614457_160614608	0.28	SLAMF1	signaling lymphocytic activation molecule family member 1	2279	0.26
chr16_29611589_29612053	0.28	ENSG00000266758	.	1235	0.4
chr6_90120799_90121205	0.28	RRAGD	Ras-related GTP binding D	787	0.65
chr16_83760457_83760608	0.28	RP11-298D21.2		550	0.74
chr16_89043094_89043288	0.28	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	210	0.92
chr2_68966290_68966892	0.28	ARHGAP25	Rho GTPase activating protein 25	4577	0.29
chr4_186706311_186706462	0.28	SORBS2	sorbin and SH3 domain containing 2	9320	0.25
chr8_121744015_121744417	0.28	RP11-713M15.1		29277	0.22
chr11_128595669_128596120	0.28	SENCR	smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA	29976	0.16
chr9_66109751_66110085	0.28	ENSG00000202474	.	348344	0.01
chr15_45005178_45005397	0.28	B2M	beta-2-microglobulin	1572	0.31
chr2_197034753_197035766	0.27	STK17B	serine/threonine kinase 17b	465	0.83
chr12_9948574_9948725	0.27	KLRF1	killer cell lectin-like receptor subfamily F, member 1	31428	0.12
chr12_6570039_6570337	0.27	TAPBPL	TAP binding protein-like	8938	0.09
chr19_21182444_21182737	0.27	ZNF430	zinc finger protein 430	20836	0.19
chr10_26737911_26738372	0.27	APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	10787	0.27
chr10_81947502_81948014	0.27	ANXA11	annexin A11	14981	0.2
chr7_142180665_142180816	0.27	PRSS3P3	protease, serine, 3 pseudogene 3	191131	0.02
chr4_99124752_99124919	0.27	ENSG00000200658	.	29900	0.18

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.5	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.2	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.4	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.4	GO:1904035	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.1	0.4	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.3	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.2	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.2	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.5	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.2	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.2	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.5	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.1	0.8	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.3	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.1	0.2	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.3	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.1	0.2	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.1	0.4	GO:0042832	defense response to protozoan(GO:0042832)
0.1	0.2	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.2	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.1	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.2	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.0	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.1	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.2	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.1	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.2	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.0	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.4	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.2	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.3	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0002830	positive regulation of type 2 immune response(GO:0002830)
0.0	0.2	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.5	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.0	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.2	GO:0046033	AMP metabolic process(GO:0046033)
0.0	0.2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.2	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.4	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.6	GO:0030101	natural killer cell activation(GO:0030101)
0.0	1.7	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.2	GO:0036230	granulocyte activation(GO:0036230)
0.0	0.1	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.2	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.6	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.0	0.1	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.3	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.4	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.2	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.3	GO:0009309	amine biosynthetic process(GO:0009309)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0007343	egg activation(GO:0007343)
0.0	0.0	GO:0032621	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0	0.1	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.1	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.2	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.2	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.0	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.1	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.0	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0032747	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.4	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.2	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.0	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.0	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.2	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.2	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.0	GO:0014805	smooth muscle adaptation(GO:0014805)
0.0	0.0	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.0	GO:0006222	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0006863	purine nucleobase transport(GO:0006863)
0.0	0.1	GO:0033151	V(D)J recombination(GO:0033151)
0.0	0.0	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0014002	astrocyte development(GO:0014002)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.2	GO:0030903	notochord development(GO:0030903)
0.0	0.0	GO:0014742	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.1	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:1903077	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.0	GO:0042940	D-amino acid transport(GO:0042940)
0.0	0.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.0	GO:0060253	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) regulation of glial cell proliferation(GO:0060251) negative regulation of glial cell proliferation(GO:0060253)
0.0	0.0	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.0	0.1	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0	0.0	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.1	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.1	GO:0018065	protein-cofactor linkage(GO:0018065)
0.0	0.0	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.2	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.0	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0015669	gas transport(GO:0015669)
0.0	0.0	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.0	GO:0060437	lung growth(GO:0060437)
0.0	0.0	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.1	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.0	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.0	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.0	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.3	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.0	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.0	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.0	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.0	GO:0010988	regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.2	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.5	GO:0000346	transcription export complex(GO:0000346)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.2	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.4	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1	0.2	GO:0000124	SAGA complex(GO:0000124)
0.1	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0001739	sex chromatin(GO:0001739)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.7	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.2	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.3	GO:0046930	pore complex(GO:0046930)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.6	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.8	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.7	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.9	GO:0030027	lamellipodium(GO:0030027)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0043209	myelin sheath(GO:0043209)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.0	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0001740	Barr body(GO:0001740)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.3	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1	0.6	GO:0005522	profilin binding(GO:0005522)
0.1	0.5	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.3	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.4	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	0.4	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.2	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.3	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.2	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.1	0.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.2	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	0.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	1.2	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.2	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.3	GO:0015288	porin activity(GO:0015288)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.3	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.4	GO:0004697	protein kinase C activity(GO:0004697)
0.0	1.6	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.3	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.8	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.2	GO:0016885	ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.0	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.0	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.3	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.5	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.3	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.0	GO:0042287	MHC protein binding(GO:0042287)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.3	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.0	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.2	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.0	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.0	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.4	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.0	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	1.0	GO:0004519	endonuclease activity(GO:0004519)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.0	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.3	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.0	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.3	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.0	GO:0016803	ether hydrolase activity(GO:0016803)
0.0	0.1	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	2.5	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.8	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.6	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.2	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.4	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.5	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.2	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.2	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	2.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.3	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.0	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.8	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.9	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.0	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.3	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.0	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.1	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.0	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing