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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for PKNOX1_TGIF2

Z-value: 0.92

Motif logo

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Transcription factors associated with PKNOX1_TGIF2

Gene Symbol Gene ID Gene Info
PKNOX1
ENSG00000160199.10 PBX/knotted 1 homeobox 1
TGIF2
ENSG00000118707.5 TGFB induced factor homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr21_44395763_44396208PKNOX112340.4256880.235.4e-01Click!
chr21_44394961_44395127PKNOX12930.8889930.186.4e-01Click!
chr21_44395511_44395752PKNOX18800.5568190.019.8e-01Click!
chr21_44393727_44394254PKNOX16300.687024-0.009.9e-01Click!
chr20_35202977_35203807TGIF23170.5528980.402.9e-01Click!
chr20_35201957_35202480TGIF22080.6484610.304.3e-01Click!
chr20_35203812_35203967TGIF28140.3584010.255.2e-01Click!
chr20_35204810_35204961TGIF218100.204835-0.098.3e-01Click!

Activity of the PKNOX1_TGIF2 motif across conditions

Conditions sorted by the z-value of the PKNOX1_TGIF2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_50144599_50144750 0.39 RCBTB1
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
 3215
 0.28
chr19_1856469_1856846 0.39 CTB-31O20.8
3592
 0.1
chrX_78621891_78622920 0.38 ITM2A
 integral membrane protein 2A
 451
 0.91
chr17_17726041_17726867 0.37 SREBF1
 sterol regulatory element binding transcription factor 1
 478
 0.73
chr7_104908860_104909472 0.37 SRPK2
 SRSF protein kinase 2
 296
 0.92
chr8_60028293_60029059 0.36 RP11-25K19.1
2923
 0.25
chr1_193154702_193155811 0.36 B3GALT2
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
 528
 0.8
chr9_33446798_33447442 0.35 AQP3
 aquaporin 3 (Gill blood group)
 489
 0.76
chr20_39677452_39677945 0.34 TOP1
 topoisomerase (DNA) I
 20240
 0.19
chr3_132349108_132349259 0.34 UBA5
 ubiquitin-like modifier activating enzyme 5
 24107
 0.16
chr20_58512577_58512765 0.33 PPP1R3D
 protein phosphatase 1, regulatory subunit 3D
 2681
 0.21
chr4_157692249_157692489 0.33 RP11-154F14.2
70142
 0.11
chr4_30725920_30726277 0.33 PCDH7
 protocadherin 7
 2121
 0.46
chr21_35305075_35305226 0.33 LINC00649
 long intergenic non-protein coding RNA 649
 1632
 0.32
chr6_64972397_64972548 0.31 RP11-349P19.1
115216
 0.07
chr1_19278015_19278216 0.31 IFFO2
 intermediate filament family orphan 2
 4077
 0.23
chr5_146257425_146257826 0.31 PPP2R2B
 protein phosphatase 2, regulatory subunit B, beta
 580
 0.82
chr11_46581548_46581763 0.31 AMBRA1
 autophagy/beclin-1 regulator 1
 31259
 0.15
chr10_99442034_99442185 0.30 AVPI1
 arginine vasopressin-induced 1
 4971
 0.16
chr17_64464860_64465690 0.29 RP11-4F22.2
52303
 0.15
chr9_33447649_33448227 0.29 AQP3
 aquaporin 3 (Gill blood group)
 329
 0.86
chr1_78468921_78469158 0.29 RP11-386I14.4
1199
 0.35
chr13_22956879_22957030 0.29 ENSG00000253094
 .
 420330
 0.01
chr6_82732214_82732365 0.29 ENSG00000223044
 .
 187868
 0.03
chr18_55930027_55930178 0.28 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
 41299
 0.16
chr2_161994699_161994850 0.28 TANK
 TRAF family member-associated NFKB activator
 1308
 0.52
chr3_31575511_31576107 0.27 STT3B
 STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
 1527
 0.55
chr13_28494142_28494415 0.27 PDX1
 pancreatic and duodenal homeobox 1
 121
 0.93
chr4_54244645_54244895 0.27 FIP1L1
 factor interacting with PAPOLA and CPSF1
 764
 0.7
chr1_108584009_108584286 0.26 ENSG00000264753
 .
 22754
 0.22
chr22_25508803_25509083 0.26 CTA-221G9.11
284
 0.93
chr16_27413508_27414237 0.26 IL21R
 interleukin 21 receptor
 377
 0.88
chr12_54891563_54891796 0.26 NCKAP1L
 NCK-associated protein 1-like
 184
 0.93
chr3_15482302_15482608 0.26 EAF1-AS1
 EAF1 antisense RNA 1
 354
 0.48
chr17_18949450_18949786 0.25 GRAP
 GRB2-related adaptor protein
 692
 0.54
chr14_93674231_93674490 0.25 UBR7
 ubiquitin protein ligase E3 component n-recognin 7 (putative)
 721
 0.44
chr17_63060035_63060186 0.25 GNA13
 guanine nucleotide binding protein (G protein), alpha 13
 7153
 0.19
chrX_72434024_72434767 0.25 NAP1L2
 nucleosome assembly protein 1-like 2
 273
 0.94
chr19_42636826_42637026 0.25 CTC-378H22.1
219
 0.52
chr18_54318050_54319471 0.25 TXNL1
 thioredoxin-like 1
 64
 0.61
chr17_19031223_19031746 0.25 GRAPL
 GRB2-related adaptor protein-like
 636
 0.51
chr10_54759512_54759663 0.24 ENSG00000201196
 .
 147220
 0.05
chr16_30710458_30711178 0.24 SRCAP
 Snf2-related CREBBP activator protein
 356
 0.48
chr17_74749100_74749251 0.24 ENSG00000200257
 .
 181
 0.89
chr2_99955142_99955293 0.24 EIF5B
 eukaryotic translation initiation factor 5B
 1401
 0.34
chr7_142425930_142426124 0.24 PRSS1
 protease, serine, 1 (trypsin 1)
 31292
 0.16
chr21_45660106_45660362 0.24 ICOSLG
 inducible T-cell co-stimulator ligand
 489
 0.69
chr1_26453661_26453812 0.24 PDIK1L
 PDLIM1 interacting kinase 1 like
 15396
 0.1
chr1_185529229_185529380 0.24 ENSG00000207108
 .
 70356
 0.11
chr9_92111480_92111784 0.24 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 715
 0.59
chr11_64013126_64013464 0.24 PPP1R14B
 protein phosphatase 1, regulatory (inhibitor) subunit 14B
 7
 0.62
chr1_40851828_40852273 0.24 SMAP2
 small ArfGAP2
 10457
 0.17
chr1_161195725_161196723 0.23 TOMM40L
 translocase of outer mitochondrial membrane 40 homolog (yeast)-like
 130
 0.84
chr18_28779454_28779605 0.23 DSC1
 desmocollin 1
 36710
 0.15
chr1_208417858_208418217 0.23 PLXNA2
 plexin A2
 372
 0.93
chr5_162930555_162931177 0.23 MAT2B
 methionine adenosyltransferase II, beta
 746
 0.62
chr6_90896871_90897022 0.23 BACH2
 BTB and CNC homology 1, basic leucine zipper transcription factor 2
 109515
 0.06
chr18_18823015_18823269 0.23 GREB1L
 growth regulation by estrogen in breast cancer-like
 823
 0.71
chr16_85673169_85673320 0.23 GSE1
 Gse1 coiled-coil protein
 14794
 0.16
chr6_149386973_149387124 0.23 RP11-162J8.3
33339
 0.2
chr6_27858007_27858288 0.23 HIST1H3J
 histone cluster 1, H3j
 423
 0.61
chr10_35089896_35090047 0.23 PARD3
 par-3 family cell polarity regulator
 14278
 0.22
chr9_18569385_18569536 0.22 ENSG00000264638
 .
 3844
 0.33
chr20_48989399_48989550 0.22 ENSG00000244376
 .
 56546
 0.13
chr1_17379619_17379770 0.22 SDHB
 succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
 971
 0.54
chr2_4455409_4455560 0.22 ENSG00000215960
 .
 179376
 0.03
chr1_228362327_228362478 0.22 IBA57
 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
 151
 0.92
chr7_75933552_75933703 0.22 HSPB1
 heat shock 27kDa protein 1
 733
 0.62
chr1_16122451_16122602 0.22 FBLIM1
 filamin binding LIM protein 1
 31078
 0.1
chr1_121159703_121159854 0.22 FCGR1B
 Fc fragment of IgG, high affinity Ib, receptor (CD64)
 223841
 0.02
chr6_139868311_139868622 0.22 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 172709
 0.03
chr20_33867276_33867427 0.22 RP4-614O4.11
495
 0.56
chr18_53296660_53296811 0.21 TCF4
 transcription factor 4
 1858
 0.49
chr8_23145924_23146455 0.21 R3HCC1
 R3H domain and coiled-coil containing 1
 254
 0.9
chr13_30528667_30528971 0.21 LINC00572
 long intergenic non-protein coding RNA 572
 28031
 0.25
chr6_167536422_167536640 0.21 CCR6
 chemokine (C-C motif) receptor 6
 272
 0.91
chr1_205462241_205462485 0.21 CDK18
 cyclin-dependent kinase 18
 11360
 0.17
chr9_126234353_126234504 0.21 RP11-230L22.4
19735
 0.22
chr18_22911937_22912088 0.21 ZNF521
 zinc finger protein 521
 19145
 0.24
chr22_18640172_18640391 0.21 USP18
 ubiquitin specific peptidase 18
 7615
 0.17
chr6_128580481_128581088 0.21 PTPRK
 protein tyrosine phosphatase, receptor type, K
 62542
 0.14
chr15_80354539_80354690 0.21 ZFAND6
 zinc finger, AN1-type domain 6
 1848
 0.41
chr1_22463869_22464020 0.20 WNT4
 wingless-type MMTV integration site family, member 4
 5515
 0.23
chr12_89855825_89855993 0.20 POC1B
 POC1 centriolar protein B
 35125
 0.15
chr10_73532392_73533248 0.20 C10orf54
 chromosome 10 open reading frame 54
 435
 0.83
chr15_33300884_33301035 0.20 ENSG00000212415
 .
 38031
 0.18
chr8_68514800_68514982 0.20 ENSG00000221660
 .
 108976
 0.07
chr15_36872415_36872566 0.20 C15orf41
 chromosome 15 open reading frame 41
 441
 0.9
chr2_11887384_11888228 0.20 LPIN1
 lipin 1
 1042
 0.41
chr15_40532008_40532159 0.20 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
 12
 0.96
chr1_72470618_72470769 0.20 NEGR1
 neuronal growth regulator 1
 95920
 0.09
chr1_201290547_201290698 0.20 PKP1
 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
 37791
 0.13
chr4_52708225_52709084 0.20 DCUN1D4
 DCN1, defective in cullin neddylation 1, domain containing 4
 575
 0.86
chr3_16522365_16522516 0.19 RFTN1
 raftlin, lipid raft linker 1
 1932
 0.44
chr18_32660928_32661079 0.19 MAPRE2
 microtubule-associated protein, RP/EB family, member 2
 39389
 0.2
chr17_38803171_38803349 0.19 SMARCE1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
 633
 0.63
chr14_22988565_22988896 0.19 TRAJ15
 T cell receptor alpha joining 15
 9850
 0.11
chr7_29233941_29234476 0.19 CHN2
 chimerin 2
 87
 0.9
chr20_56275354_56275505 0.19 PMEPA1
 prostate transmembrane protein, androgen induced 1
 8543
 0.26
chr10_25869445_25869596 0.19 ENSG00000222543
 .
 186747
 0.03
chr10_134261699_134261957 0.19 C10orf91
 chromosome 10 open reading frame 91
 3135
 0.24
chr17_40274740_40274891 0.19 HSPB9
 heat shock protein, alpha-crystallin-related, B9
 59
 0.94
chr19_34717882_34718033 0.19 KIAA0355
 KIAA0355
 27485
 0.19
chr1_208418253_208418520 0.19 PLXNA2
 plexin A2
 721
 0.82
chr2_204801338_204802214 0.19 ICOS
 inducible T-cell co-stimulator
 273
 0.95
chr14_100842881_100843420 0.19 WARS
 tryptophanyl-tRNA synthetase
 8
 0.78
chr5_40685855_40686084 0.19 PTGER4
 prostaglandin E receptor 4 (subtype EP4)
 6369
 0.22
chr4_78743157_78743308 0.19 CNOT6L
 CCR4-NOT transcription complex, subunit 6-like
 2463
 0.37
chr5_176237821_176238145 0.19 UNC5A
 unc-5 homolog A (C. elegans)
 505
 0.84
chr17_72756037_72756203 0.19 SLC9A3R1
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
 2022
 0.18
chr6_106961305_106961653 0.19 AIM1
 absent in melanoma 1
 1749
 0.38
chr8_26249046_26249197 0.19 BNIP3L
 BCL2/adenovirus E1B 19kDa interacting protein 3-like
 1243
 0.5
chr2_129365909_129366162 0.19 ENSG00000238379
 .
 163263
 0.04
chr17_4762663_4762814 0.18 ENSG00000263599
 .
 16183
 0.08
chr6_13761461_13761614 0.18 MCUR1
 mitochondrial calcium uniporter regulator 1
 40040
 0.15
chr1_117910944_117911674 0.18 MAN1A2
 mannosidase, alpha, class 1A, member 2
 1238
 0.61
chr8_119452205_119452425 0.18 SAMD12
 sterile alpha motif domain containing 12
 140806
 0.05
chr12_92440588_92440837 0.18 C12orf79
 chromosome 12 open reading frame 79
 90085
 0.08
chr8_59718017_59718168 0.18 ENSG00000201231
 .
 9019
 0.29
chr22_27441616_27441767 0.18 ENSG00000200443
 .
 9841
 0.32
chr12_14525729_14525880 0.18 ATF7IP
 activating transcription factor 7 interacting protein
 5497
 0.26
chr15_71300550_71300701 0.18 LRRC49
 leucine rich repeat containing 49
 71751
 0.1
chr1_27028870_27029082 0.18 ARID1A
 AT rich interactive domain 1A (SWI-like)
 6081
 0.16
chr1_215020458_215020609 0.18 KCNK2
 potassium channel, subfamily K, member 2
 158665
 0.04
chr4_34195647_34195839 0.18 ENSG00000263814
 .
 192716
 0.03
chr22_31335429_31335580 0.18 MORC2
 MORC family CW-type zinc finger 2
 6623
 0.16
chr7_45614612_45614823 0.18 ADCY1
 adenylate cyclase 1 (brain)
 596
 0.84
chr5_139283271_139283734 0.18 NRG2
 neuregulin 2
 480
 0.84
chr4_83956375_83957237 0.18 COPS4
 COP9 signalosome subunit 4
 428
 0.82
chr1_4606573_4606724 0.18 AJAP1
 adherens junctions associated protein 1
 108144
 0.08
chr16_89381066_89381217 0.18 AC137932.6
6400
 0.14
chr2_229949087_229949238 0.18 PID1
 phosphotyrosine interaction domain containing 1
 147639
 0.05
chr1_17541747_17541898 0.18 PADI1
 peptidyl arginine deiminase, type I
 10201
 0.17
chr8_129005826_129005977 0.18 ENSG00000207110
 .
 5476
 0.19
chr1_6453925_6454377 0.17 ACOT7
 acyl-CoA thioesterase 7
 300
 0.65
chr11_77062251_77062402 0.17 PAK1
 p21 protein (Cdc42/Rac)-activated kinase 1
 1994
 0.4
chr2_23736447_23736598 0.17 AC011239.1
 Uncharacterized protein
 10692
 0.3
chr1_9653728_9653879 0.17 TMEM201
 transmembrane protein 201
 3152
 0.26
chr19_31830955_31831409 0.17 AC007796.1
8605
 0.25
chr7_48675933_48676084 0.17 ABCA13
 ATP-binding cassette, sub-family A (ABC1), member 13
 128540
 0.06
chr19_42626071_42626364 0.17 POU2F2
 POU class 2 homeobox 2
 515
 0.63
chr17_16944854_16945024 0.17 MPRIP
 myosin phosphatase Rho interacting protein
 920
 0.58
chr11_59473933_59474084 0.17 ENSG00000223223
 .
 152
 0.93
chr7_127023381_127023532 0.17 ZNF800
 zinc finger protein 800
 8716
 0.24
chr19_54676940_54677234 0.17 TMC4
 transmembrane channel-like 4
 143
 0.89
chr14_56662445_56662672 0.17 PELI2
 pellino E3 ubiquitin protein ligase family member 2
 76731
 0.11
chr12_118455272_118455463 0.17 RFC5
 replication factor C (activator 1) 5, 36.5kDa
 833
 0.64
chr18_13567514_13567726 0.17 RP11-53B2.4
2586
 0.2
chr16_56945671_56945822 0.17 HERPUD1
 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
 20214
 0.11
chr18_30049396_30050442 0.17 GAREM
 GRB2 associated, regulator of MAPK1
 476
 0.87
chr11_9272154_9272305 0.17 RP11-5L12.1
5173
 0.21
chr3_58012091_58012242 0.17 FLNB
 filamin B, beta
 18039
 0.25
chr11_62321822_62322177 0.17 AHNAK
 AHNAK nucleoprotein
 1708
 0.18
chr11_44588275_44588433 0.16 CD82
 CD82 molecule
 1081
 0.58
chr7_115850994_115851250 0.16 TES
 testis derived transcript (3 LIM domains)
 519
 0.82
chr9_100748941_100749092 0.16 RP11-535C21.3
922
 0.5
chr2_96812420_96812577 0.16 DUSP2
 dual specificity phosphatase 2
 1319
 0.38
chr3_107317640_107318380 0.16 BBX
 bobby sox homolog (Drosophila)
 150
 0.98
chr11_69079389_69079561 0.16 MYEOV
 myeloma overexpressed
 17850
 0.27
chrX_118071502_118071653 0.16 LONRF3
 LON peptidase N-terminal domain and ring finger 3
 37004
 0.2
chr16_88490951_88491102 0.16 ZNF469
 zinc finger protein 469
 2853
 0.26
chr3_182983612_182983806 0.16 B3GNT5
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
 577
 0.77
chr13_30267514_30267665 0.16 SLC7A1
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
 97764
 0.08
chr19_30792538_30792689 0.16 ZNF536
 zinc finger protein 536
 70706
 0.12
chr20_43150070_43150299 0.16 SERINC3
 serine incorporator 3
 467
 0.76
chrX_22153236_22153476 0.16 PHEX
 phosphate regulating endopeptidase homolog, X-linked
 37534
 0.16
chr16_57831320_57831471 0.16 KIFC3
 kinesin family member C3
 281
 0.88
chr20_47757335_47757486 0.16 STAU1
 staufen double-stranded RNA binding protein 1
 33390
 0.16
chr2_86114637_86114901 0.16 ST3GAL5
 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
 97
 0.97
chr12_51015115_51015266 0.16 ENSG00000207136
 .
 11866
 0.21
chr17_8907022_8907441 0.16 NTN1
 netrin 1
 17628
 0.22
chr2_175197056_175197207 0.16 SP9
 Sp9 transcription factor
 2543
 0.24
chr16_31076129_31076313 0.16 ZNF668
 zinc finger protein 668
 69
 0.86
chr2_64441847_64441998 0.16 AC074289.1
7813
 0.27
chr20_39786785_39786936 0.16 RP1-1J6.2
20217
 0.18
chr5_153416653_153416804 0.16 FAM114A2
 family with sequence similarity 114, member A2
 142
 0.95
chr4_40517752_40517903 0.16 RBM47
 RNA binding motif protein 47
 163
 0.96
chrX_130020204_130020367 0.16 ENOX2
 ecto-NOX disulfide-thiol exchanger 2
 16893
 0.28
chr8_62621050_62621416 0.16 ASPH
 aspartate beta-hydroxylase
 5851
 0.24
chr12_53781982_53782414 0.16 SP1
 Sp1 transcription factor
 7112
 0.13
chr10_126314631_126314782 0.16 FAM53B-AS1
 FAM53B antisense RNA 1
 77488
 0.09
chr1_156785141_156785328 0.16 NTRK1
 neurotrophic tyrosine kinase, receptor, type 1
 214
 0.87
chr13_103251895_103252050 0.16 TPP2
 tripeptidyl peptidase II
 2599
 0.29
chr4_31171719_31171870 0.16 RP11-619J20.1
376202
 0.01
chr11_1909549_1909755 0.16 C11orf89
 chromosome 11 open reading frame 89
 2432
 0.16
chr9_43133207_43133798 0.16 ANKRD20A3
 ankyrin repeat domain 20 family, member A3
 42
 0.97
chr1_36173086_36173270 0.16 ENSG00000239859
 .
 1303
 0.39
chr8_143443109_143443260 0.16 TSNARE1
 t-SNARE domain containing 1
 7060
 0.23
chr21_36562046_36562197 0.16 RUNX1
 runt-related transcription factor 1
 140480
 0.05
chr18_11487781_11487932 0.15 NPIPB1P
 nuclear pore complex interacting protein family, member B1, pseudogene
 151604
 0.04
chr17_3289151_3289302 0.15 RP11-64J4.2
361
 0.82
chr4_1228146_1228426 0.15 CTBP1
 C-terminal binding protein 1
 6214
 0.15
chr18_68267310_68267461 0.15 GTSCR1
 Gilles de la Tourette syndrome chromosome region, candidate 1
 50562
 0.17
chr5_112824477_112824726 0.15 MCC
 mutated in colorectal cancers
 74
 0.97
chr2_131798149_131798300 0.15 ARHGEF4
 Rho guanine nucleotide exchange factor (GEF) 4
 626
 0.76
chr1_67893569_67893720 0.15 SERBP1
 SERPINE1 mRNA binding protein 1
 2411
 0.31
chr8_1791296_1791447 0.15 ARHGEF10
 Rho guanine nucleotide exchange factor (GEF) 10
 17094
 0.2
chr10_104420612_104420763 0.15 TRIM8
 tripartite motif containing 8
 16043
 0.16
chr9_18689231_18689382 0.15 ENSG00000252960
 .
 38161
 0.2
chr3_150059920_150060071 0.15 TSC22D2
 TSC22 domain family, member 2
 66127
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0070295 renal water absorption(GO:0070295)
0.1 0.4 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.3 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.4 GO:0021535 cell migration in hindbrain(GO:0021535)
0.1 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.2 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.2 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.1 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0014889 muscle atrophy(GO:0014889)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.0 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.0 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.0 0.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.2 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0042482 positive regulation of odontogenesis(GO:0042482)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.2 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0045217 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.1 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.0 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.0 GO:0070293 renal absorption(GO:0070293)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.0 GO:0032351 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.3 GO:0009267 cellular response to starvation(GO:0009267)
0.0 0.0 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.0 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0071883 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0009067 aspartate family amino acid biosynthetic process(GO:0009067)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.0 GO:1901722 regulation of cell proliferation involved in kidney development(GO:1901722)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.0 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.0 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.0 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.0 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.0 GO:2000095 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.3 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.0 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.0 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.0 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.0 GO:0051379 alpha2-adrenergic receptor activity(GO:0004938) epinephrine binding(GO:0051379)
0.0 0.0 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0001067 regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 PID ATR PATHWAY ATR signaling pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated