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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for PLAG1

Z-value: 0.51

Motif logo

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Transcription factors associated with PLAG1

Gene Symbol Gene ID Gene Info
PLAG1
ENSG00000181690.3 PLAG1 zinc finger

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr8_57086542_57086822PLAG1371560.1216550.599.3e-02Click!
chr8_57122306_57122457PLAG114570.3536000.571.1e-01Click!
chr8_57123539_57123769PLAG11840.830733-0.521.5e-01Click!
chr8_57086200_57086351PLAG1375630.1206650.511.6e-01Click!
chr8_57122958_57123494PLAG16120.588802-0.412.7e-01Click!

Activity of the PLAG1 motif across conditions

Conditions sorted by the z-value of the PLAG1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chrX_54947220_54948504 0.29 TRO
 trophinin
 41
 0.97
chr14_105436556_105437076 0.21 AHNAK2
 AHNAK nucleoprotein 2
 7878
 0.16
chr2_74666737_74667617 0.19 RTKN
 rhotekin
 533
 0.54
chr5_131593477_131594185 0.19 PDLIM4
 PDZ and LIM domain 4
 431
 0.81
chr20_55204347_55205219 0.19 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
 425
 0.81
chr7_100464814_100466140 0.18 TRIP6
 thyroid hormone receptor interactor 6
 717
 0.47
chr16_4985840_4986055 0.18 PPL
 periplakin
 1118
 0.43
chr1_156073604_156073917 0.16 LMNA
 lamin A/C
 10701
 0.1
chr17_7308835_7309309 0.16 NLGN2
 neuroligin 2
 879
 0.24
chr18_10454899_10455524 0.15 APCDD1
 adenomatosis polyposis coli down-regulated 1
 232
 0.95
chr3_194494197_194494348 0.15 FAM43A
 family with sequence similarity 43, member A
 87650
 0.07
chr17_70116228_70116580 0.14 SOX9
 SRY (sex determining region Y)-box 9
 757
 0.79
chr11_62312562_62314176 0.14 RP11-864I4.4
102
 0.64
chr22_50783104_50783895 0.14 PPP6R2
 protein phosphatase 6, regulatory subunit 2
 1739
 0.21
chr6_44424385_44424803 0.14 ENSG00000266619
 .
 21216
 0.17
chr4_186560086_186560237 0.14 SORBS2
 sorbin and SH3 domain containing 2
 10599
 0.18
chr17_36861833_36863162 0.13 CTB-58E17.3
17
 0.9
chr3_24562978_24563646 0.13 ENSG00000265028
 .
 386
 0.87
chr14_79745937_79746359 0.13 NRXN3
 neurexin 3
 101
 0.98
chr3_64430574_64431219 0.12 PRICKLE2
 prickle homolog 2 (Drosophila)
 162
 0.97
chr2_189156294_189156511 0.12 GULP1
 GULP, engulfment adaptor PTB domain containing 1
 6
 0.98
chr17_59476045_59476898 0.12 RP11-332H18.4
260
 0.74
chr2_218843405_218844030 0.12 TNS1
 tensin 1
 60
 0.79
chr6_34205466_34206794 0.12 HMGA1
 high mobility group AT-hook 1
 438
 0.85
chr2_85505218_85505417 0.12 ENSG00000221579
 .
 20840
 0.12
chr16_3162631_3163041 0.12 ZNF205
 zinc finger protein 205
 40
 0.8
chr10_135148565_135149526 0.11 CALY
 calcyon neuron-specific vesicular protein
 1331
 0.22
chr11_118478413_118479735 0.11 PHLDB1
 pleckstrin homology-like domain, family B, member 1
 716
 0.54
chr9_130330127_130331202 0.11 FAM129B
 family with sequence similarity 129, member B
 703
 0.67
chr19_6740138_6741070 0.11 TRIP10
 thyroid hormone receptor interactor 10
 325
 0.81
chr3_49237110_49237583 0.11 CCDC36
 coiled-coil domain containing 36
 403
 0.74
chr11_131780761_131781452 0.10 NTM
 neurotrimin
 209
 0.95
chr6_129203821_129204789 0.10 LAMA2
 laminin, alpha 2
 37
 0.99
chrX_37430984_37431427 0.10 LANCL3
 LanC lantibiotic synthetase component C-like 3 (bacterial)
 300
 0.94
chr1_35246823_35247104 0.10 GJB3
 gap junction protein, beta 3, 31kDa
 173
 0.91
chr7_70159815_70160908 0.10 AUTS2
 autism susceptibility candidate 2
 33764
 0.25
chrX_110038687_110039773 0.10 CHRDL1
 chordin-like 1
 56
 0.99
chr7_555957_556150 0.10 PDGFA
 platelet-derived growth factor alpha polypeptide
 2092
 0.33
chr17_76879212_76879961 0.10 TIMP2
 TIMP metallopeptidase inhibitor 2
 9354
 0.14
chr7_95401616_95402462 0.10 DYNC1I1
 dynein, cytoplasmic 1, intermediate chain 1
 123
 0.98
chr17_41622177_41622554 0.10 RP11-392O1.4
212
 0.81
chrX_68348217_68348929 0.10 PJA1
 praja ring finger 1, E3 ubiquitin protein ligase
 33964
 0.24
chr20_51589535_51589784 0.10 TSHZ2
 teashirt zinc finger homeobox 2
 713
 0.79
chr8_145020311_145020609 0.10 PLEC
 plectin
 113
 0.91
chr5_139283809_139284341 0.10 NRG2
 neuregulin 2
 93
 0.98
chr15_61520624_61520983 0.10 RORA
 RAR-related orphan receptor A
 715
 0.73
chr15_80544489_80544852 0.10 FAH
 fumarylacetoacetate hydrolase (fumarylacetoacetase)
 96377
 0.07
chr1_3816010_3816785 0.10 C1orf174
 chromosome 1 open reading frame 174
 452
 0.8
chr2_1711742_1712354 0.09 PXDN
 peroxidasin homolog (Drosophila)
 15706
 0.26
chr1_34629900_34630098 0.09 CSMD2
 CUB and Sushi multiple domains 2
 876
 0.55
chr6_138427325_138427625 0.09 PERP
 PERP, TP53 apoptosis effector
 1173
 0.59
chr6_13924445_13925088 0.09 RNF182
 ring finger protein 182
 89
 0.98
chr1_199728481_199728632 0.09 ENSG00000200139
 .
 128731
 0.05
chr6_146755289_146755690 0.09 ENSG00000222971
 .
 93933
 0.09
chr14_101034010_101035263 0.09 BEGAIN
 brain-enriched guanylate kinase-associated
 192
 0.93
chr9_13568681_13569117 0.09 MPDZ
 multiple PDZ domain protein
 289310
 0.01
chr1_39598517_39598955 0.09 ENSG00000206654
 .
 12021
 0.17
chr7_2842191_2842738 0.09 GNA12
 guanine nucleotide binding protein (G protein) alpha 12
 12428
 0.25
chr18_5629293_5629838 0.09 ENSG00000252432
 .
 32484
 0.15
chr17_79317268_79317735 0.09 TMEM105
 transmembrane protein 105
 13027
 0.13
chr11_93063544_93063792 0.09 CCDC67
 coiled-coil domain containing 67
 143
 0.97
chr18_53253101_53253291 0.09 TCF4
 transcription factor 4
 1
 0.99
chr5_1110808_1112337 0.09 SLC12A7
 solute carrier family 12 (potassium/chloride transporter), member 7
 578
 0.75
chrX_153687680_153687951 0.09 PLXNA3
 plexin A3
 1194
 0.23
chr2_71127433_71128165 0.08 VAX2
 ventral anterior homeobox 2
 79
 0.96
chr17_1018223_1018374 0.08 ABR
 active BCR-related
 378
 0.88
chr1_27321840_27321991 0.08 TRNP1
 TMF1-regulated nuclear protein 1
 1105
 0.44
chr10_6780355_6780830 0.08 PRKCQ
 protein kinase C, theta
 158329
 0.04
chr16_576320_577633 0.08 CAPN15
 calpain 15
 741
 0.43
chr20_55205529_55205819 0.08 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
 264
 0.9
chr3_50194015_50194506 0.08 RP11-493K19.3
742
 0.47
chr16_86542600_86543872 0.08 FOXF1
 forkhead box F1
 897
 0.62
chr2_235353840_235353991 0.08 ARL4C
 ADP-ribosylation factor-like 4C
 51329
 0.19
chrX_135230110_135230418 0.08 FHL1
 four and a half LIM domains 1
 6
 0.98
chrX_114796055_114796359 0.08 PLS3
 plastin 3
 625
 0.52
chrX_56258780_56259711 0.08 KLF8
 Kruppel-like factor 8
 235
 0.96
chr2_220492846_220493097 0.08 SLC4A3
 solute carrier family 4 (anion exchanger), member 3
 588
 0.57
chr7_1497923_1498578 0.08 MICALL2
 MICAL-like 2
 712
 0.54
chr5_155107689_155108219 0.08 ENSG00000200275
 .
 164493
 0.04
chrX_48930794_48931951 0.08 PRAF2
 PRA1 domain family, member 2
 276
 0.78
chr7_45128395_45129126 0.08 NACAD
 NAC alpha domain containing
 247
 0.87
chr3_52566781_52567334 0.08 NT5DC2
 5'-nucleotidase domain containing 2
 490
 0.67
chr17_34998121_34998780 0.08 MRM1
 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
 40059
 0.13
chr9_132936080_132936268 0.08 NCS1
 neuronal calcium sensor 1
 1317
 0.47
chr15_41795749_41795900 0.08 ITPKA
 inositol-trisphosphate 3-kinase A
 9751
 0.13
chr11_63530349_63531105 0.08 ENSG00000264519
 .
 34816
 0.12
chr22_50744615_50744936 0.08 PLXNB2
 plexin B2
 1242
 0.27
chr19_39528811_39528970 0.07 FBXO27
 F-box protein 27
 5465
 0.12
chrX_122317435_122317817 0.07 GRIA3
 glutamate receptor, ionotropic, AMPA 3
 380
 0.93
chr8_125739093_125740062 0.07 MTSS1
 metastasis suppressor 1
 280
 0.94
chr12_127939879_127940274 0.07 ENSG00000253089
 .
 134176
 0.05
chr1_34631046_34631197 0.07 CSMD2
 CUB and Sushi multiple domains 2
 246
 0.89
chr17_34611752_34612896 0.07 CCL3L1
 chemokine (C-C motif) ligand 3-like 1
 13395
 0.14
chr13_113840712_113840863 0.07 RP11-98F14.11
21290
 0.11
chr8_68896954_68897148 0.07 PREX2
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
 32698
 0.23
chr19_13129320_13129532 0.07 CTC-239J10.1
4101
 0.11
chr8_99439239_99439631 0.07 KCNS2
 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
 185
 0.95
chr9_140785598_140785749 0.07 RP11-188C12.3
1349
 0.47
chr16_31076512_31076791 0.07 AC135050.5
165
 0.57
chr19_10341031_10341948 0.07 ENSG00000264266
 .
 400
 0.34
chr10_100027380_100027945 0.07 LOXL4
 lysyl oxidase-like 4
 345
 0.9
chr4_153274070_153274464 0.07 FBXW7
 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
 144
 0.97
chr11_66102741_66104078 0.07 RIN1
 Ras and Rab interactor 1
 468
 0.53
chr5_139126785_139127680 0.07 ENSG00000200756
 .
 29557
 0.16
chr7_158608170_158608321 0.07 ESYT2
 extended synaptotagmin-like protein 2
 13918
 0.24
chr1_196577305_196577474 0.07 KCNT2
 potassium channel, subfamily T, member 2
 100
 0.97
chr4_21949961_21950371 0.07 KCNIP4
 Kv channel interacting protein 4
 202
 0.77
chr7_150759622_150760148 0.07 SLC4A2
 solute carrier family 4 (anion exchanger), member 2
 164
 0.88
chr6_28511380_28512171 0.07 GPX5
 glutathione peroxidase 5 (epididymal androgen-related protein)
 17986
 0.16
chr6_113966553_113966868 0.07 ENSG00000266650
 .
 42593
 0.17
chr3_79815928_79816150 0.07 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
 926
 0.74
chr8_22224818_22225894 0.07 SLC39A14
 solute carrier family 39 (zinc transporter), member 14
 305
 0.9
chr3_173302379_173302636 0.07 NLGN1
 neuroligin 1
 162
 0.98
chr7_44185024_44185674 0.07 GCK
 glucokinase (hexokinase 4)
 394
 0.74
chr1_94091019_94091233 0.07 BCAR3
 breast cancer anti-estrogen resistance 3
 11472
 0.22
chr7_73868670_73869167 0.07 GTF2IRD1
 GTF2I repeat domain containing 1
 479
 0.83
chrX_107018688_107019917 0.07 TSC22D3
 TSC22 domain family, member 3
 43
 0.97
chr6_110679391_110679830 0.07 METTL24
 methyltransferase like 24
 135
 0.97
chr12_3308931_3310293 0.07 TSPAN9
 tetraspanin 9
 729
 0.75
chr6_154800458_154800845 0.07 CNKSR3
 CNKSR family member 3
 1026
 0.69
chr5_151065179_151065606 0.07 SPARC
 secreted protein, acidic, cysteine-rich (osteonectin)
 601
 0.67
chr8_94712271_94712761 0.07 FAM92A1
 family with sequence similarity 92, member A1
 36
 0.63
chr11_126872809_126873319 0.07 KIRREL3-AS3
 KIRREL3 antisense RNA 3
 259
 0.89
chr19_3097315_3097524 0.07 GNA11
 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
 3011
 0.15
chr1_180881914_180882730 0.07 KIAA1614
 KIAA1614
 3
 0.98
chr2_230845561_230845747 0.07 ENSG00000206725
 .
 7623
 0.17
chrX_51811538_51811884 0.07 MAGED4B
 melanoma antigen family D, 4B
 557
 0.75
chr1_16470072_16470223 0.07 RP11-276H7.2
11559
 0.12
chr14_50809347_50809713 0.07 CDKL1
 cyclin-dependent kinase-like 1 (CDC2-related kinase)
 1683
 0.33
chr2_113997514_113997878 0.07 RP11-65I12.1
611
 0.6
chr11_128760172_128761028 0.07 KCNJ5
 potassium inwardly-rectifying channel, subfamily J, member 5
 651
 0.68
chr19_1355185_1356018 0.07 MUM1
 melanoma associated antigen (mutated) 1
 625
 0.53
chr12_3069053_3070004 0.07 TEAD4
 TEA domain family member 4
 445
 0.77
chr9_91793130_91793737 0.07 SHC3
 SHC (Src homology 2 domain containing) transforming protein 3
 249
 0.95
chr5_167197787_167197938 0.07 TENM2
 teneurin transmembrane protein 2
 15854
 0.23
chr22_43115644_43116713 0.07 A4GALT
 alpha 1,4-galactosyltransferase
 24539
 0.15
chr19_51161641_51162497 0.07 C19orf81
 chromosome 19 open reading frame 81
 9024
 0.12
chr16_15529020_15529579 0.07 C16orf45
 chromosome 16 open reading frame 45
 967
 0.56
chr21_46875019_46875466 0.07 COL18A1
 collagen, type XVIII, alpha 1
 161
 0.95
chr3_52016673_52017699 0.07 ABHD14B
 abhydrolase domain containing 14B
 239
 0.49
chr19_45754620_45755932 0.06 MARK4
 MAP/microtubule affinity-regulating kinase 4
 726
 0.57
chr22_25348691_25349626 0.06 KIAA1671
 KIAA1671
 461
 0.83
chr17_42620836_42621052 0.06 FZD2
 frizzled family receptor 2
 13981
 0.17
chr17_48074174_48074657 0.06 DLX3
 distal-less homeobox 3
 1827
 0.28
chr14_31733126_31733307 0.06 ENSG00000199291
 .
 5301
 0.16
chr1_215256670_215256888 0.06 KCNK2
 potassium channel, subfamily K, member 2
 81
 0.99
chr16_88850139_88851147 0.06 PIEZO1
 piezo-type mechanosensitive ion channel component 1
 976
 0.35
chrX_135258076_135258227 0.06 FHL1
 four and a half LIM domains 1
 6066
 0.24
chr15_96865528_96865838 0.06 NR2F2-AS1
 NR2F2 antisense RNA 1
 191
 0.93
chr21_28214648_28215240 0.06 ADAMTS1
 ADAM metallopeptidase with thrombospondin type 1 motif, 1
 393
 0.9
chr18_48086527_48087582 0.06 MAPK4
 mitogen-activated protein kinase 4
 42
 0.99
chr10_102759781_102760726 0.06 LZTS2
 leucine zipper, putative tumor suppressor 2
 643
 0.52
chr14_101543718_101544133 0.06 ENSG00000207959
 .
 10864
 0.02
chr2_218874842_218875310 0.06 TNS1
 tensin 1
 7358
 0.19
chr10_64564066_64565253 0.06 ADO
 2-aminoethanethiol (cysteamine) dioxygenase
 143
 0.92
chr17_47075525_47076053 0.06 IGF2BP1
 insulin-like growth factor 2 mRNA binding protein 1
 681
 0.41
chr3_125690962_125691349 0.06 ROPN1B
 rhophilin associated tail protein 1B
 3098
 0.23
chr5_79252602_79252869 0.06 RP11-168A11.1
20333
 0.2
chr22_29703700_29703885 0.06 GAS2L1
 growth arrest-specific 2 like 1
 744
 0.49
chr12_81471441_81472090 0.06 ACSS3
 acyl-CoA synthetase short-chain family member 3
 71
 0.98
chr17_43483002_43483407 0.06 ARHGAP27
 Rho GTPase activating protein 27
 96
 0.95
chr10_33622786_33623487 0.06 NRP1
 neuropilin 1
 174
 0.97
chr17_21279729_21280949 0.06 KCNJ12
 potassium inwardly-rectifying channel, subfamily J, member 12
 830
 0.69
chr16_29690426_29691035 0.06 QPRT
 quinolinate phosphoribosyltransferase
 227
 0.89
chr16_55542879_55544136 0.06 LPCAT2
 lysophosphatidylcholine acyltransferase 2
 597
 0.77
chr7_2678463_2678614 0.06 TTYH3
 tweety family member 3
 6628
 0.2
chr14_77964628_77965267 0.06 ISM2
 isthmin 2
 212
 0.91
chr2_119592973_119593692 0.06 EN1
 engrailed homeobox 1
 11922
 0.28
chr19_37743129_37743340 0.06 ZNF383
 zinc finger protein 383
 24782
 0.13
chr1_113265808_113265959 0.06 FAM19A3
 family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
 2684
 0.16
chr6_44264722_44265466 0.06 TCTE1
 t-complex-associated-testis-expressed 1
 331
 0.81
chr12_116892640_116892791 0.06 ENSG00000264037
 .
 26592
 0.24
chr5_141744007_141744207 0.06 AC005592.2
10999
 0.25
chr19_41104181_41104507 0.06 LTBP4
 latent transforming growth factor beta binding protein 4
 1203
 0.38
chr17_26732645_26733444 0.06 SLC46A1
 solute carrier family 46 (folate transporter), member 1
 184
 0.8
chr17_79989895_79990665 0.06 RAC3
 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
 220
 0.81
chr11_2230168_2230319 0.06 ENSG00000265258
 .
 35950
 0.09
chr22_46299339_46299556 0.06 WNT7B
 wingless-type MMTV integration site family, member 7B
 69148
 0.09
chr20_62600161_62600928 0.06 ZNF512B
 zinc finger protein 512B
 674
 0.45
chr16_4422135_4423224 0.06 VASN
 vasorin
 830
 0.49
chr17_34059454_34059687 0.06 RASL10B
 RAS-like, family 10, member B
 902
 0.43
chr9_128729332_128729483 0.06 PBX3
 pre-B-cell leukemia homeobox 3
 101857
 0.08
chr16_85203170_85204140 0.06 CTC-786C10.1
1227
 0.55
chr10_112258642_112259418 0.06 DUSP5
 dual specificity phosphatase 5
 1434
 0.41
chr7_42533422_42533764 0.06 GLI3
 GLI family zinc finger 3
 256935
 0.02
chr6_43243068_43244292 0.06 SLC22A7
 solute carrier family 22 (organic anion transporter), member 7
 22056
 0.11
chr11_68451782_68452060 0.06 GAL
 galanin/GMAP prepropeptide
 22
 0.98
chr2_162931613_162931764 0.06 DPP4
 dipeptidyl-peptidase 4
 636
 0.69
chr12_50975264_50975415 0.06 ENSG00000207136
 .
 51717
 0.12
chr16_68679865_68680079 0.06 RP11-615I2.2
99
 0.91
chr3_170469573_170469724 0.06 ENSG00000222411
 .
 90313
 0.08
chr6_150740165_150740632 0.06 IYD
 iodotyrosine deiodinase
 49285
 0.16
chr21_38352575_38353327 0.06 HLCS
 holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
 23
 0.97
chr7_51383611_51384133 0.06 COBL
 cordon-bleu WH2 repeat protein
 296
 0.95
chr3_85007676_85007999 0.06 CADM2
 cell adhesion molecule 2
 295
 0.94
chr2_213401284_213401530 0.06 ERBB4
 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
 1846
 0.51
chr9_126761184_126761335 0.06 LHX2
 LIM homeobox 2
 2690
 0.23
chr11_106888657_106888832 0.06 GUCY1A2
 guanylate cyclase 1, soluble, alpha 2
 133
 0.98
chr19_41725635_41725911 0.06 AXL
 AXL receptor tyrosine kinase
 633
 0.58
chr14_105434049_105434298 0.06 AHNAK2
 AHNAK nucleoprotein 2
 10521
 0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of PLAG1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0072182 nephron tubule epithelial cell differentiation(GO:0072160) regulation of nephron tubule epithelial cell differentiation(GO:0072182) regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0072217 negative regulation of metanephros development(GO:0072217)
0.0 0.0 GO:0060463 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0 0.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.0 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.4 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0003181 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.0 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.0 0.1 GO:1901890 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.0 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.2 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.0 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.0 GO:0051590 positive regulation of neurotransmitter transport(GO:0051590)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0045683 negative regulation of epidermis development(GO:0045683)
0.0 0.0 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.0 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.0 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.0 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels