Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
Navigation
Downloads
Logo

Results for POU2F2_POU3F1

Z-value: 0.74

Motif logo

logo of logo of

Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
POU2F2
ENSG00000028277.16 POU class 2 homeobox 2
POU3F1
ENSG00000185668.5 POU class 3 homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr19_42617987_42618295POU2F228980.138953-0.723.0e-02Click!
chr19_42592755_42592969POU2F266950.106865-0.665.4e-02Click!
chr19_42618337_42618532POU2F226050.148628-0.521.5e-01Click!
chr19_42626536_42626691POU2F21190.9264350.491.8e-01Click!
chr19_42618636_42618787POU2F223280.160988-0.472.0e-01Click!
chr1_38504855_38505006POU3F175200.148058-0.561.1e-01Click!
chr1_38510021_38510235POU3F123220.237855-0.501.7e-01Click!
chr1_38512756_38512948POU3F14020.815332-0.432.5e-01Click!
chr1_38512142_38512303POU3F12280.913864-0.383.2e-01Click!
chr1_38513049_38513583POU3F18660.543140-0.353.5e-01Click!

Activity of the POU2F2_POU3F1 motif across conditions

Conditions sorted by the z-value of the POU2F2_POU3F1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_40551802_40551953 0.40 LRRK2
 leucine-rich repeat kinase 2
 38669
 0.17
chr20_47435196_47435347 0.34 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 9149
 0.27
chr7_36763519_36763817 0.34 AOAH
 acyloxyacyl hydrolase (neutrophil)
 386
 0.9
chr2_198756913_198757256 0.33 PLCL1
 phospholipase C-like 1
 82102
 0.1
chr7_50351765_50352753 0.32 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 3941
 0.34
chr17_8857533_8857684 0.31 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 11416
 0.24
chrX_153190817_153191535 0.30 ARHGAP4
 Rho GTPase activating protein 4
 522
 0.6
chrX_78407653_78407829 0.30 GPR174
 G protein-coupled receptor 174
 18728
 0.29
chr19_41808988_41809179 0.30 CCDC97
 coiled-coil domain containing 97
 7011
 0.11
chr11_118305386_118306890 0.30 RP11-770J1.4
217
 0.83
chr11_6766362_6766695 0.26 GVINP1
 GTPase, very large interferon inducible pseudogene 1
 23417
 0.11
chr8_27237031_27237182 0.26 PTK2B
 protein tyrosine kinase 2 beta
 1062
 0.59
chr4_113209604_113209755 0.26 TIFA
 TRAF-interacting protein with forkhead-associated domain
 2620
 0.23
chr9_95822109_95822464 0.26 SUSD3
 sushi domain containing 3
 1225
 0.45
chr17_29641266_29641417 0.26 EVI2B
 ecotropic viral integration site 2B
 211
 0.9
chr13_99911056_99911338 0.25 GPR18
 G protein-coupled receptor 18
 515
 0.8
chr4_165040749_165040900 0.25 MARCH1
 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
 264317
 0.02
chr5_56484038_56484189 0.25 GPBP1
 GC-rich promoter binding protein 1
 12340
 0.23
chr3_71632242_71632973 0.25 FOXP1
 forkhead box P1
 297
 0.91
chr5_10632325_10632658 0.24 ANKRD33B-AS1
 ANKRD33B antisense RNA 1
 4154
 0.28
chr2_231586611_231586796 0.24 CAB39
 calcium binding protein 39
 8440
 0.22
chr5_130883505_130884015 0.24 RAPGEF6
 Rap guanine nucleotide exchange factor (GEF) 6
 15034
 0.29
chr21_15916676_15916915 0.23 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
 1867
 0.42
chr7_33078848_33079779 0.23 NT5C3A
 5'-nucleotidase, cytosolic IIIA
 1208
 0.42
chr1_239883177_239883989 0.23 CHRM3
 cholinergic receptor, muscarinic 3
 740
 0.59
chr11_34649048_34649199 0.23 EHF
 ets homologous factor
 3300
 0.35
chr6_13397968_13398119 0.23 GFOD1
 glucose-fructose oxidoreductase domain containing 1
 10326
 0.22
chr7_137620232_137620510 0.23 CREB3L2
 cAMP responsive element binding protein 3-like 2
 1735
 0.39
chr1_6520196_6520500 0.22 TNFRSF25
 tumor necrosis factor receptor superfamily, member 25
 5342
 0.12
chr18_22045724_22045875 0.22 HRH4
 histamine receptor H4
 5106
 0.18
chr14_99701823_99701974 0.22 AL109767.1
27387
 0.19
chr2_175456254_175456405 0.22 WIPF1
 WAS/WASL interacting protein family, member 1
 6012
 0.19
chr7_26192485_26193339 0.22 NFE2L3
 nuclear factor, erythroid 2-like 3
 1052
 0.53
chr9_274295_274630 0.22 DOCK8
 dedicator of cytokinesis 8
 1392
 0.34
chrX_129218649_129218800 0.22 ELF4
 E74-like factor 4 (ets domain transcription factor)
 25612
 0.18
chr15_69074948_69075145 0.21 ENSG00000265195
 .
 19218
 0.22
chr1_169679248_169679951 0.21 SELL
 selectin L
 1240
 0.48
chr9_34957337_34957488 0.20 KIAA1045
 KIAA1045
 72
 0.97
chr18_60965137_60965288 0.20 RP11-28F1.2
16103
 0.17
chr15_75080868_75081404 0.20 ENSG00000264386
 .
 38
 0.76
chr22_27067492_27067685 0.20 CRYBA4
 crystallin, beta A4
 49660
 0.13
chr3_141129590_141129741 0.20 ZBTB38
 zinc finger and BTB domain containing 38
 8005
 0.24
chr17_73341947_73342237 0.20 RP11-16C1.3
1606
 0.24
chr17_75878240_75878391 0.20 FLJ45079
344
 0.91
chr17_58602582_58603600 0.20 APPBP2
 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
 393
 0.59
chr2_192014047_192014198 0.20 STAT4
 signal transducer and activator of transcription 4
 1575
 0.44
chr15_101786887_101787230 0.19 CHSY1
 chondroitin sulfate synthase 1
 5079
 0.19
chr19_44123855_44124353 0.19 ZNF428
 zinc finger protein 428
 78
 0.93
chr1_211780216_211780378 0.19 RP11-359E8.5
23230
 0.15
chr7_138729622_138729773 0.19 ZC3HAV1L
 zinc finger CCCH-type, antiviral 1-like
 8922
 0.21
chr2_233940706_233940970 0.19 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
 15649
 0.18
chr7_31851936_31852087 0.19 ENSG00000223070
 .
 18149
 0.28
chr6_35570444_35570718 0.19 ENSG00000212579
 .
 49014
 0.11
chr17_8801498_8801803 0.19 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 13174
 0.21
chr10_11218203_11218399 0.19 RP3-323N1.2
4962
 0.24
chr19_54873446_54873661 0.19 LAIR1
 leukocyte-associated immunoglobulin-like receptor 1
 997
 0.38
chr1_185663326_185663550 0.19 HMCN1
 hemicentin 1
 40245
 0.17
chr2_182176845_182176996 0.19 ENSG00000266705
 .
 6541
 0.33
chr3_151027973_151028124 0.19 GPR87
 G protein-coupled receptor 87
 6692
 0.18
chr19_6801414_6802010 0.19 VAV1
 vav 1 guanine nucleotide exchange factor
 17583
 0.13
chr20_52370448_52370599 0.18 ENSG00000238468
 .
 85226
 0.09
chr10_14227081_14227239 0.18 RP11-397C18.2
110877
 0.06
chrX_48776392_48776920 0.18 PIM2
 pim-2 oncogene
 355
 0.76
chr19_47378667_47378818 0.18 AP2S1
 adaptor-related protein complex 2, sigma 1 subunit
 24493
 0.14
chr1_29253817_29254129 0.18 EPB41
 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
 12882
 0.18
chr14_73885671_73885822 0.18 NUMB
 numb homolog (Drosophila)
 8967
 0.19
chr1_206729975_206731239 0.18 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 114
 0.96
chr3_3214293_3214763 0.18 CRBN
 cereblon
 6830
 0.19
chr14_35306917_35307068 0.18 ENSG00000251726
 .
 7574
 0.17
chr8_66748492_66748643 0.18 PDE7A
 phosphodiesterase 7A
 2416
 0.41
chr3_197875188_197875339 0.18 AC073135.3
38186
 0.14
chr18_45018917_45019068 0.18 ENSG00000266582
 .
 112125
 0.07
chr14_22747947_22748098 0.18 ENSG00000238634
 .
 137135
 0.04
chr15_100050578_100050729 0.17 AC015660.1
 HCG1993240; Serologically defined breast cancer antigen NY-BR-40; Uncharacterized protein
 12075
 0.22
chr11_9714574_9714725 0.17 ENSG00000201564
 .
 12178
 0.18
chr2_230198282_230198433 0.17 PID1
 phosphotyrosine interaction domain containing 1
 62356
 0.14
chr19_18507804_18508682 0.17 LRRC25
 leucine rich repeat containing 25
 178
 0.89
chr19_16461941_16462107 0.17 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 10740
 0.14
chr2_120687963_120688114 0.17 PTPN4
 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
 686
 0.74
chrX_1640522_1640673 0.17 P2RY8
 purinergic receptor P2Y, G-protein coupled, 8
 15403
 0.2
chr2_198143570_198143721 0.17 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 23598
 0.16
chr12_79960142_79960293 0.17 PAWR
 PRKC, apoptosis, WT1, regulator
 30097
 0.18
chr2_113945705_113945856 0.17 PSD4
 pleckstrin and Sec7 domain containing 4
 8077
 0.14
chrY_1590520_1590671 0.17 NA
 NA
 > 106
 NA
chr1_236056952_236057103 0.17 LYST
 lysosomal trafficking regulator
 10155
 0.17
chr7_37448490_37448719 0.17 ENSG00000200113
 .
 10627
 0.2
chr1_19789578_19789845 0.17 CAPZB
 capping protein (actin filament) muscle Z-line, beta
 20868
 0.15
chr2_158977628_158977779 0.17 UPP2-IT1
 UPP2 intronic transcript 1 (non-protein coding)
 6766
 0.22
chr11_121365458_121365609 0.17 RP11-730K11.1
41811
 0.18
chr13_46750556_46750707 0.17 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 5828
 0.17
chr3_172235814_172236037 0.16 TNFSF10
 tumor necrosis factor (ligand) superfamily, member 10
 5340
 0.27
chr2_198064690_198065196 0.16 ANKRD44
 ankyrin repeat domain 44
 2181
 0.29
chr10_59856470_59856621 0.16 ENSG00000238970
 .
 141976
 0.05
chr7_36327271_36327770 0.16 EEPD1
 endonuclease/exonuclease/phosphatase family domain containing 1
 9233
 0.18
chr11_121298288_121298439 0.16 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 24549
 0.21
chr7_25902012_25902163 0.16 ENSG00000199085
 .
 87519
 0.1
chr4_35416147_35416298 0.16 ENSG00000206665
 .
 81298
 0.12
chr8_90031831_90031982 0.16 RP11-586K2.1
319386
 0.01
chr1_167059294_167059481 0.16 GPA33
 glycoprotein A33 (transmembrane)
 481
 0.77
chr7_2550958_2551215 0.16 LFNG
 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
 1077
 0.47
chr11_128595669_128596120 0.16 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 29976
 0.16
chr14_106471583_106471884 0.16 IGHV1-3
 immunoglobulin heavy variable 1-3
 10
 0.91
chr17_17603690_17604249 0.16 RAI1
 retinoic acid induced 1
 18160
 0.17
chr6_70219788_70219939 0.16 ENSG00000265362
 .
 111402
 0.07
chr7_7960072_7960471 0.16 ENSG00000201747
 .
 14121
 0.18
chr2_201985007_201985268 0.16 CFLAR
 CASP8 and FADD-like apoptosis regulator
 1923
 0.24
chr6_90066974_90067553 0.16 UBE2J1
 ubiquitin-conjugating enzyme E2, J1
 4696
 0.23
chr10_97154601_97154752 0.15 SORBS1
 sorbin and SH3 domain containing 1
 20776
 0.25
chr1_36270069_36270220 0.15 AGO4
 argonaute RISC catalytic component 4
 3629
 0.22
chr1_15342375_15342526 0.15 KAZN
 kazrin, periplakin interacting protein
 70035
 0.12
chrX_12989756_12990021 0.15 TMSB4X
 thymosin beta 4, X-linked
 3339
 0.29
chr6_16687583_16687734 0.15 RP1-151F17.1
73711
 0.11
chr3_146258052_146258203 0.15 PLSCR1
 phospholipid scramblase 1
 4181
 0.23
chr22_36805845_36806656 0.15 MYH9
 myosin, heavy chain 9, non-muscle
 22187
 0.14
chr20_49073623_49073774 0.15 ENSG00000244376
 .
 27678
 0.17
chr6_170604225_170605407 0.15 FAM120B
 family with sequence similarity 120B
 407
 0.83
chr12_57636595_57636960 0.15 NDUFA4L2
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
 2302
 0.16
chr14_51280034_51280250 0.15 RP11-286O18.1
8456
 0.15
chr1_161523849_161524000 0.15 RP11-5K23.5
2944
 0.16
chr6_42513326_42513477 0.15 UBR2
 ubiquitin protein ligase E3 component n-recognin 2
 18399
 0.19
chr2_68995729_68995971 0.15 ARHGAP25
 Rho GTPase activating protein 25
 6083
 0.26
chr14_73931285_73931436 0.15 ENSG00000251393
 .
 2231
 0.24
chr1_25887785_25888064 0.15 LDLRAP1
 low density lipoprotein receptor adaptor protein 1
 17853
 0.19
chr4_55809328_55809479 0.15 ENSG00000264332
 .
 67696
 0.11
chr1_9711350_9712072 0.15 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 79
 0.97
chr8_82066026_82066177 0.15 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 41798
 0.19
chr3_39006420_39006571 0.15 SCN11A
 sodium channel, voltage-gated, type XI, alpha subunit
 14443
 0.19
chr13_50810191_50810488 0.15 ENSG00000221198
 .
 127034
 0.05
chr8_62604897_62605048 0.15 ASPH
 aspartate beta-hydroxylase
 2564
 0.34
chr7_133116374_133116525 0.15 EXOC4
 exocyst complex component 4
 144767
 0.05
chr11_40034818_40034969 0.15 ENSG00000221804
 .
 151749
 0.04
chr18_9559122_9559273 0.15 RP11-881L2.1
28187
 0.13
chr1_25889724_25889930 0.14 LDLRAP1
 low density lipoprotein receptor adaptor protein 1
 19756
 0.18
chr11_47386705_47386856 0.14 MYBPC3
 myosin binding protein C, cardiac
 12527
 0.09
chr6_43214536_43215130 0.14 TTBK1
 tau tubulin kinase 1
 894
 0.48
chr1_221927643_221927794 0.14 DUSP10
 dual specificity phosphatase 10
 12200
 0.29
chr20_33732566_33732717 0.14 EDEM2
 ER degradation enhancer, mannosidase alpha-like 2
 318
 0.85
chr12_76658709_76658860 0.14 ENSG00000223273
 .
 50747
 0.15
chr16_28235213_28235364 0.14 XPO6
 exportin 6
 12047
 0.18
chr4_2939568_2939719 0.14 NOP14-AS1
 NOP14 antisense RNA 1
 265
 0.88
chr9_97121768_97121919 0.14 HIATL1
 hippocampus abundant transcript-like 1
 14990
 0.2
chr14_61793464_61793615 0.14 PRKCH
 protein kinase C, eta
 92
 0.97
chr11_48041704_48041855 0.14 AC103828.1
4372
 0.25
chr16_3265391_3265542 0.14 OR1F1
 olfactory receptor, family 1, subfamily F, member 1
 11219
 0.1
chr16_50874988_50875494 0.14 ENSG00000199771
 .
 28245
 0.15
chr14_35754560_35754711 0.14 ENSG00000265530
 .
 6057
 0.23
chr20_55550076_55550227 0.14 ENSG00000251772
 .
 24992
 0.22
chr15_52023462_52024365 0.14 LYSMD2
 LysM, putative peptidoglycan-binding, domain containing 2
 6405
 0.15
chr1_161605235_161605386 0.14 FCGR3B
 Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
 3557
 0.15
chr6_130848326_130848477 0.14 ENSG00000202438
 .
 46856
 0.17
chr7_38392270_38392581 0.14 AMPH
 amphiphysin
 110288
 0.07
chr1_235120289_235120440 0.14 ENSG00000239690
 .
 80431
 0.1
chr3_172240144_172241280 0.14 TNFSF10
 tumor necrosis factor (ligand) superfamily, member 10
 553
 0.83
chr8_141607200_141607468 0.14 AGO2
 argonaute RISC catalytic component 2
 8653
 0.24
chrX_109351614_109351783 0.14 ENSG00000265584
 .
 26352
 0.2
chr5_125785966_125786206 0.14 GRAMD3
 GRAM domain containing 3
 11951
 0.22
chr20_48448748_48448899 0.14 ENSG00000252123
 .
 4294
 0.19
chr12_15102775_15102926 0.14 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
 779
 0.6
chr17_40425804_40425955 0.14 AC003104.1
1178
 0.32
chr16_17510234_17510944 0.13 XYLT1
 xylosyltransferase I
 54149
 0.18
chr1_206900182_206900333 0.13 ENSG00000199349
 .
 21180
 0.14
chr18_13465441_13465744 0.13 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
 578
 0.59
chr1_198896471_198896622 0.13 ENSG00000207759
 .
 68264
 0.12
chr2_175357999_175358525 0.13 GPR155
 G protein-coupled receptor 155
 6440
 0.21
chr1_81935804_81935955 0.13 RP5-837I24.6
34905
 0.21
chr8_129289122_129289410 0.13 ENSG00000201782
 .
 56516
 0.16
chr18_56307433_56307584 0.13 ALPK2
 alpha-kinase 2
 11319
 0.15
chr17_76714885_76715036 0.13 CYTH1
 cytohesin 1
 1853
 0.36
chr1_161154335_161154531 0.13 B4GALT3
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
 7146
 0.07
chr2_216922950_216923179 0.13 PECR
 peroxisomal trans-2-enoyl-CoA reductase
 23475
 0.15
chr2_198006679_198006830 0.13 ANKRD44
 ankyrin repeat domain 44
 5874
 0.27
chr15_101792013_101793187 0.13 CHSY1
 chondroitin sulfate synthase 1
 463
 0.8
chr8_49416567_49416718 0.13 RP11-770E5.1
47485
 0.19
chr7_130643743_130643906 0.13 LINC-PINT
 long intergenic non-protein coding RNA, p53 induced transcript
 25044
 0.22
chr13_111108512_111108663 0.13 COL4A2-AS2
 COL4A2 antisense RNA 2
 7047
 0.22
chr10_73512307_73512458 0.13 C10orf54
 chromosome 10 open reading frame 54
 5005
 0.22
chr11_14666941_14667162 0.13 PDE3B
 phosphodiesterase 3B, cGMP-inhibited
 1674
 0.36
chr8_55064954_55065105 0.13 ENSG00000251835
 .
 413
 0.86
chr4_90222893_90223044 0.13 GPRIN3
 GPRIN family member 3
 6193
 0.32
chr1_198651611_198651863 0.13 RP11-553K8.5
15547
 0.24
chr19_6890241_6890675 0.13 EMR1
 egf-like module containing, mucin-like, hormone receptor-like 1
 2868
 0.21
chrX_147462452_147462756 0.13 AC002368.4
119531
 0.06
chr3_45985242_45985393 0.13 CXCR6
 chemokine (C-X-C motif) receptor 6
 353
 0.85
chr8_21776103_21776686 0.13 XPO7
 exportin 7
 786
 0.64
chrX_118751905_118752056 0.13 NKRF
 NFKB repressing factor
 12122
 0.15
chr6_11986707_11986858 0.13 RP11-456H18.1
5463
 0.27
chr7_75085913_75086064 0.13 POM121C
 POM121 transmembrane nucleoporin C
 13995
 0.12
chr2_168252602_168252753 0.13 XIRP2
 xin actin-binding repeat containing 2
 208884
 0.03
chr3_53742016_53742167 0.12 CACNA1D
 calcium channel, voltage-dependent, L type, alpha 1D subunit
 41016
 0.16
chr12_98912505_98912656 0.12 TMPO-AS1
 TMPO antisense RNA 1
 2380
 0.2
chr14_52778923_52779116 0.12 PTGER2
 prostaglandin E receptor 2 (subtype EP2), 53kDa
 2004
 0.41
chr11_23251355_23251506 0.12 ENSG00000264478
 .
 241829
 0.02
chr3_39302441_39302592 0.12 CX3CR1
 chemokine (C-X3-C motif) receptor 1
 19009
 0.19
chr1_56111785_56112048 0.12 ENSG00000272051
 .
 161271
 0.04
chr5_32583768_32584065 0.12 SUB1
 SUB1 homolog (S. cerevisiae)
 1689
 0.49
chr14_99702038_99702570 0.12 AL109767.1
26981
 0.19
chr6_15882568_15882719 0.12 DTNBP1
 dystrobrevin binding protein 1
 219370
 0.02
chr2_32489606_32489792 0.12 NLRC4
 NLR family, CARD domain containing 4
 250
 0.92
chr12_125405765_125405916 0.12 UBC
 ubiquitin C
 3926
 0.19
chr1_181050920_181051071 0.12 IER5
 immediate early response 5
 6643
 0.23

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.3 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.2 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.0 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0002885 positive regulation of hypersensitivity(GO:0002885)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.0 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.0 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.0 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0016045 detection of bacterium(GO:0016045)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244)
0.0 0.0 GO:0045409 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.0 GO:0046643 regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.0 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle