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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for POU5F1_POU2F3

Z-value: 2.87

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol	Gene ID	Gene Info
POU5F1 Ensembl NCBI GeneCards UniProt	ENSG00000204531.11	POU class 5 homeobox 1
POU2F3 Ensembl NCBI GeneCards UniProt	ENSG00000137709.5	POU class 2 homeobox 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_120110982_120111133	POU2F3	154	0.951324	-0.50	1.7e-01	Click!
chr11_120095962_120096113	POU2F3	11312	0.160189	-0.44	2.4e-01	Click!
chr11_120119674_120119825	POU2F3	8846	0.171166	0.43	2.5e-01	Click!
chr11_120094706_120094857	POU2F3	12568	0.157293	-0.34	3.7e-01	Click!
chr11_120095512_120095663	POU2F3	11762	0.159136	-0.18	6.5e-01	Click!
chr6_31147991_31148192	POU5F1	417	0.674033	-0.25	5.1e-01	Click!
chr6_31148269_31148530	POU5F1	109	0.920496	-0.16	6.9e-01	Click!

Activity of the POU5F1_POU2F3 motif across conditions

Conditions sorted by the z-value of the POU5F1_POU2F3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_197825673_197826397	1.58	AC073135.3		11042	0.16
chr3_197831468_197832400	1.43	AC073135.3		5143	0.19
chr12_117420918_117421075	1.29	RP11-231I16.1		4146	0.28
chr11_118305386_118306890	1.17	RP11-770J1.4		217	0.83
chr21_28214648_28215240	1.15	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	393	0.9
chr11_126869922_126870139	1.02	KIRREL3	kin of IRRE like 3 (Drosophila)	386	0.81
chr2_216299376_216299642	0.97	FN1	fibronectin 1	1281	0.4
chr6_161860389_161860563	0.95	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4	165383	0.04
chr12_54611665_54611918	0.93	ENSG00000265371	.	13469	0.1
chr22_46423027_46423794	0.91	RP6-109B7.5		25563	0.09
chr5_126626527_126627025	0.90	MEGF10	multiple EGF-like-domains 10	225	0.95
chr13_30027327_30027478	0.89	MTUS2	microtubule associated tumor suppressor candidate 2	24556	0.22
chr3_190391964_190392141	0.88	ENSG00000223117	.	32100	0.21
chr5_134825154_134825603	0.88	TIFAB	TRAF-interacting protein with forkhead-associated domain, family member B	37289	0.11
chr7_19154676_19154916	0.87	TWIST1	twist family bHLH transcription factor 1	2499	0.21
chr4_71997150_71997347	0.87	SLC4A4	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	55755	0.16
chr5_121409447_121409998	0.86	LOX	lysyl oxidase	4258	0.27
chrX_69674453_69675874	0.85	DLG3	discs, large homolog 3 (Drosophila)	217	0.75
chr1_33358402_33358643	0.85	HPCA	hippocalcin	6486	0.13
chrX_128656025_128656195	0.84	SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	1350	0.49
chr8_49832237_49832502	0.83	SNAI2	snail family zinc finger 2	1619	0.54
chr4_177244788_177244939	0.83	RP11-87F15.2		3254	0.25
chr7_100464814_100466140	0.82	TRIP6	thyroid hormone receptor interactor 6	717	0.47
chr19_30719241_30719606	0.82	ZNF536	zinc finger protein 536	2	0.73
chr15_23931247_23932124	0.82	NDN	necdin, melanoma antigen (MAGE) family member	765	0.7
chrX_10587548_10588615	0.82	MID1	midline 1 (Opitz/BBB syndrome)	378	0.91
chr19_29492860_29493011	0.80	ENSG00000252272	.	358	0.93
chr4_113739356_113739869	0.79	ANK2	ankyrin 2, neuronal	347	0.9
chr14_27065895_27066046	0.78	NOVA1	neuro-oncological ventral antigen 1	318	0.85
chr11_57545200_57545645	0.77	CTNND1	catenin (cadherin-associated protein), delta 1	3653	0.19
chr13_65834890_65835427	0.77	ENSG00000221685	.	603147	0.0
chr8_42063953_42065062	0.77	PLAT	plasminogen activator, tissue	576	0.71
chr5_111091378_111091829	0.76	NREP	neuronal regeneration related protein	345	0.9
chrX_34673071_34673254	0.76	TMEM47	transmembrane protein 47	2243	0.48
chr12_52400775_52401965	0.76	GRASP	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein	646	0.62
chr6_16200733_16201077	0.76	ENSG00000251831	.	4340	0.21
chr11_64126691_64127568	0.74	RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	373	0.73
chr3_16219029_16219297	0.74	GALNT15	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15	2947	0.33
chr4_17060566_17060738	0.74	LDB2	LIM domain binding 2	160220	0.04
chr9_128521797_128522422	0.74	PBX3	pre-B-cell leukemia homeobox 3	11631	0.27
chr8_77599524_77599676	0.72	ZFHX4	zinc finger homeobox 4	3584	0.28
chr3_197828693_197828955	0.72	AC073135.3		8253	0.17
chr8_119963118_119963285	0.72	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	1238	0.55
chr7_77647061_77647212	0.72	RP5-1185I7.1		27399	0.25
chr6_138862905_138863056	0.72	NHSL1	NHS-like 1	3868	0.32
chr5_125475185_125475336	0.72	ENSG00000265637	.	57268	0.17
chrX_130962862_130963372	0.71	ENSG00000200587	.	109867	0.07
chr11_114237431_114237671	0.71	RP11-64D24.2		10258	0.16
chr7_102554933_102555219	0.71	LRRC17	leucine rich repeat containing 17	1624	0.38
chr10_123900999_123901504	0.71	TACC2	transforming, acidic coiled-coil containing protein 2	15022	0.26
chr6_19691587_19692480	0.70	ENSG00000200957	.	49273	0.18
chr2_66670252_66670507	0.70	MEIS1	Meis homeobox 1	282	0.85
chr13_102105579_102105898	0.70	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	720	0.77
chr9_12792360_12792511	0.69	LURAP1L	leucine rich adaptor protein 1-like	17415	0.18
chr4_81191052_81191243	0.69	FGF5	fibroblast growth factor 5	3354	0.31
chr10_116451084_116451252	0.69	ABLIM1	actin binding LIM protein 1	6754	0.26
chr12_13350846_13351208	0.68	EMP1	epithelial membrane protein 1	1307	0.55
chr1_196622943_196623164	0.68	CFH	complement factor H	1867	0.41
chr4_128545168_128545319	0.68	INTU	inturned planar cell polarity protein	817	0.75
chr10_95766689_95766956	0.67	PLCE1	phospholipase C, epsilon 1	13076	0.21
chr7_28111372_28111552	0.67	JAZF1	JAZF zinc finger 1	159	0.97
chr12_72669274_72669551	0.66	ENSG00000236333	.	725	0.69
chr10_114741340_114741544	0.66	RP11-57H14.2		29808	0.19
chr9_14098246_14098397	0.66	NFIB	nuclear factor I/B	82470	0.11
chr16_54970178_54971110	0.66	IRX5	iroquois homeobox 5	4660	0.36
chr12_115340794_115340945	0.65	ENSG00000252459	.	165360	0.04
chr7_106787828_106787991	0.65	CTA-360L10.1		13731	0.2
chr20_4129930_4130735	0.65	SMOX	spermine oxidase	750	0.71
chr5_87952392_87952543	0.65	ENSG00000245526	.	10290	0.21
chr3_114136352_114136558	0.65	ZBTB20-AS1	ZBTB20 antisense RNA 1	29939	0.18
chr10_98272514_98273588	0.64	TLL2	tolloid-like 2	617	0.79
chr16_64245174_64245639	0.64	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	848175	0.0
chr11_27276125_27276386	0.64	RP11-1L12.3		34595	0.21
chr15_83239771_83240251	0.64	CPEB1	cytoplasmic polyadenylation element binding protein 1	498	0.71
chr6_151648337_151648657	0.64	AKAP12	A kinase (PRKA) anchor protein 12	1674	0.27
chr2_175203994_175204145	0.64	AC018470.1	Uncharacterized protein FLJ46347	1918	0.29
chrX_122319779_122319930	0.63	GRIA3	glutamate receptor, ionotropic, AMPA 3	1089	0.69
chr5_92948054_92948286	0.63	ENSG00000251725	.	8324	0.21
chr4_153272766_153273041	0.63	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	1220	0.52
chr3_157053767_157053918	0.63	ENSG00000243176	.	49893	0.16
chr6_43214536_43215130	0.63	TTBK1	tau tubulin kinase 1	894	0.48
chr8_20126437_20126669	0.63	LZTS1	leucine zipper, putative tumor suppressor 1	13750	0.19
chr4_183890629_183890780	0.62	DCTD	dCMP deaminase	51615	0.15
chr3_116582620_116583104	0.62	ENSG00000265433	.	13648	0.25
chr13_24154580_24154749	0.62	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1145	0.64
chr4_54523037_54523201	0.62	RP11-317M11.1		2256	0.32
chr15_96878987_96879612	0.61	ENSG00000222651	.	2809	0.21
chr6_100316163_100316348	0.61	MCHR2-AS1	MCHR2 antisense RNA 1	125565	0.05
chr15_42749974_42750162	0.61	ZNF106	zinc finger protein 106	314	0.87
chr12_54591479_54591630	0.61	SMUG1	single-strand-selective monofunctional uracil-DNA glycosylase 1	8776	0.11
chr2_145235800_145235951	0.61	ZEB2	zinc finger E-box binding homeobox 2	39240	0.18
chr17_30658222_30658373	0.60	C17orf75	chromosome 17 open reading frame 75	3265	0.19
chr5_146835005_146835156	0.60	DPYSL3	dihydropyrimidinase-like 3	1251	0.58
chr4_116035249_116035478	0.60	NDST4	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4	331	0.94
chr6_45523951_45524153	0.60	ENSG00000252738	.	89789	0.09
chr2_161491867_161492018	0.60	RBMS1	RNA binding motif, single stranded interacting protein 1	141637	0.05
chr21_17444306_17444457	0.60	ENSG00000252273	.	36552	0.23
chr1_35914565_35914729	0.59	KIAA0319L	KIAA0319-like	5661	0.2
chr4_116194347_116194498	0.59	NDST4	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4	159390	0.04
chr14_90126270_90126545	0.59	ENSG00000252655	.	9160	0.16
chr8_146204034_146204185	0.59	RP5-1047A19.4		14191	0.15
chr11_78508450_78508601	0.58	TENM4	teneurin transmembrane protein 4	7931	0.27
chr7_63923820_63924465	0.58	ZNF680	zinc finger protein 680	99277	0.08
chr1_14219689_14219912	0.58	PRDM2	PR domain containing 2, with ZNF domain	121579	0.06
chr9_91653559_91653931	0.58	SHC3	SHC (Src homology 2 domain containing) transforming protein 3	3307	0.28
chr2_198126557_198126708	0.58	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	40611	0.13
chr1_244836322_244836473	0.58	DESI2	desumoylating isopeptidase 2	19344	0.23
chr2_243030793_243031816	0.58	AC093642.5		460	0.62
chr12_115250983_115251152	0.58	ENSG00000252459	.	75558	0.12
chr21_27607980_27608165	0.58	ENSG00000206802	.	45046	0.16
chr4_110223153_110224430	0.58	COL25A1	collagen, type XXV, alpha 1	8	0.99
chr13_76212170_76212445	0.57	LMO7	LIM domain 7	1848	0.28
chr17_58821066_58821723	0.57	ENSG00000252534	.	5013	0.22
chr13_74637272_74637666	0.57	KLF12	Kruppel-like factor 12	68283	0.14
chr6_144008458_144008841	0.57	PHACTR2	phosphatase and actin regulator 2	9444	0.27
chr4_7937771_7938061	0.57	AC097381.1		2812	0.26
chr5_159510482_159510643	0.57	PWWP2A	PWWP domain containing 2A	35867	0.14
chr1_236308030_236308327	0.57	GPR137B	G protein-coupled receptor 137B	2110	0.37
chrX_139793107_139793258	0.57	LINC00632	long intergenic non-protein coding RNA 632	1250	0.53
chr6_166419889_166420278	0.57	ENSG00000252196	.	64254	0.12
chr1_217263352_217263815	0.56	ESRRG	estrogen-related receptor gamma	607	0.86
chr9_20558698_20558876	0.56	ENSG00000252324	.	17429	0.2
chr1_196576976_196577127	0.56	KCNT2	potassium channel, subfamily T, member 2	438	0.86
chr18_18697656_18697875	0.56	ENSG00000251886	.	2702	0.29
chr2_66668625_66669005	0.56	AC092669.1		153	0.89
chr5_82577485_82577636	0.56	VCAN	versican	189724	0.03
chr3_181285218_181285513	0.56	SOX2-OT	SOX2 overlapping transcript (non-protein coding)	3856	0.36
chr8_72754626_72756069	0.56	RP11-383H13.1	Protein LOC100132891; cDNA FLJ53548	20	0.96
chr3_157154723_157155399	0.56	PTX3	pentraxin 3, long	483	0.86
chr3_87030882_87031292	0.56	VGLL3	vestigial like 3 (Drosophila)	8765	0.33
chr11_112848535_112848686	0.56	ENSG00000238998	.	535	0.79
chr12_52257745_52258098	0.56	ANKRD33	ankyrin repeat domain 33	23823	0.16
chr3_77091074_77091225	0.56	ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	1268	0.6
chr2_20648707_20648907	0.55	RHOB	ras homolog family member B	1972	0.34
chr2_3465758_3466116	0.55	TRAPPC12	trafficking protein particle complex 12	3507	0.21
chr4_151001634_151001785	0.55	DCLK2	doublecortin-like kinase 2	1529	0.55
chr7_120632386_120632537	0.55	CPED1	cadherin-like and PC-esterase domain containing 1	2785	0.27
chr17_73126799_73128080	0.55	NT5C	5', 3'-nucleotidase, cytosolic	23	0.94
chr8_41200524_41200675	0.55	SFRP1	secreted frizzled-related protein 1	33583	0.15
chr3_112798260_112798787	0.55	ENSG00000238593	.	12849	0.18
chr6_141884450_141884959	0.55	ENSG00000222764	.	77155	0.13
chr9_80638102_80638399	0.55	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	7270	0.32
chr3_187930915_187931066	0.55	LPP	LIM domain containing preferred translocation partner in lipoma	269	0.94
chr4_16897303_16897454	0.54	LDB2	LIM domain binding 2	2807	0.43
chr5_119782760_119782911	0.54	PRR16	proline rich 16	17138	0.29
chr21_39227684_39227918	0.54	KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6	57756	0.14
chr21_48080967_48081118	0.54	PRMT2	protein arginine methyltransferase 2	16787	0.23
chr5_39420318_39420469	0.54	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	4577	0.31
chr3_197829934_197830170	0.54	AC073135.3		7025	0.18
chr3_25470623_25470774	0.54	RARB	retinoic acid receptor, beta	896	0.71
chr6_132520617_132520826	0.53	ENSG00000265669	.	84318	0.1
chr10_76349397_76349548	0.53	ENSG00000206756	.	38322	0.19
chr4_163085121_163085733	0.53	FSTL5	follistatin-like 5	240	0.96
chr11_94528311_94528492	0.53	AMOTL1	angiomotin like 1	26864	0.2
chr17_63738678_63738916	0.53	CEP112	centrosomal protein 112kDa	8045	0.32
chrX_39949292_39950247	0.53	BCOR	BCL6 corepressor	6887	0.33
chr1_200343235_200343386	0.53	ZNF281	zinc finger protein 281	35810	0.22
chr2_72684771_72684922	0.53	ENSG00000222536	.	264089	0.02
chr7_120630679_120630951	0.53	CPED1	cadherin-like and PC-esterase domain containing 1	1139	0.51
chr4_3323595_3323746	0.53	RGS12	regulator of G-protein signaling 12	5875	0.26
chr3_133020578_133020729	0.53	RP11-402L6.1		44621	0.17
chr5_77147504_77148481	0.53	TBCA	tubulin folding cofactor A	16612	0.28
chr1_164546141_164546408	0.53	PBX1	pre-B-cell leukemia homeobox 1	14232	0.25
chr6_149368169_149368320	0.53	RP11-162J8.3		14535	0.25
chr1_32230049_32230559	0.53	BAI2	brain-specific angiogenesis inhibitor 2	190	0.92
chr9_137097669_137097820	0.52	ENSG00000221676	.	68058	0.1
chr3_173460576_173460750	0.52	NLGN1	neuroligin 1	138274	0.05
chr10_89435565_89435716	0.52	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	14932	0.19
chr14_77491443_77491668	0.52	IRF2BPL	interferon regulatory factor 2 binding protein-like	3479	0.25
chr22_40845374_40845546	0.52	MKL1	megakaryoblastic leukemia (translocation) 1	13962	0.16
chr6_143508631_143508782	0.52	AIG1	androgen-induced 1	61319	0.13
chr21_17652021_17652264	0.52	ENSG00000201025	.	4947	0.35
chr9_16704056_16704545	0.52	BNC2	basonuclin 2	780	0.71
chr13_45145551_45145847	0.52	TSC22D1	TSC22 domain family, member 1	4693	0.31
chr12_3308931_3310293	0.51	TSPAN9	tetraspanin 9	729	0.75
chr7_111079006_111079157	0.51	IMMP2L	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)	46110	0.2
chr5_124194835_124194993	0.51	ZNF608	zinc finger protein 608	110414	0.06
chr11_10690622_10690773	0.51	MRVI1	murine retrovirus integration site 1 homolog	16774	0.18
chr19_9608666_9608918	0.51	ZNF560	zinc finger protein 560	491	0.79
chr1_201506374_201506568	0.51	CSRP1	cysteine and glycine-rich protein 1	27887	0.14
chr5_71453247_71453481	0.51	ENSG00000264099	.	11930	0.23
chr5_53444022_53444173	0.51	ENSG00000265421	.	72684	0.11
chr8_77317816_77317967	0.51	ENSG00000222231	.	139924	0.05
chr11_83392322_83392502	0.51	DLG2	discs, large homolog 2 (Drosophila)	637	0.8
chr6_139692606_139692757	0.51	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	2669	0.37
chr6_6752053_6752282	0.51	LY86-AS1	LY86 antisense RNA 1	129163	0.05
chr9_117658240_117658391	0.51	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	34382	0.2
chr15_66994787_66995642	0.51	SMAD6	SMAD family member 6	540	0.83
chr3_8561489_8561767	0.51	LMCD1	LIM and cysteine-rich domains 1	17241	0.2
chr11_111849006_111849202	0.51	DIXDC1	DIX domain containing 1	1071	0.39
chr2_217144138_217144289	0.51	AC012513.6		19895	0.17
chr1_186153285_186153546	0.51	GS1-174L6.4		6981	0.23
chr2_10122063_10122214	0.51	GRHL1	grainyhead-like 1 (Drosophila)	13296	0.16
chr15_42749089_42749416	0.51	ZNF106	zinc finger protein 106	459	0.78
chr8_93284767_93284918	0.51	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	169328	0.04
chr3_185531595_185531973	0.50	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	7065	0.24
chr21_17960305_17960805	0.50	ENSG00000207863	.	2002	0.4
chr6_22329035_22329186	0.50	PRL	prolactin	31380	0.23
chr5_167003606_167003757	0.50	CTB-78F1.1		83805	0.1
chr13_80705528_80705730	0.50	SPRY2	sprouty homolog 2 (Drosophila)	208165	0.03

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3	1.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3	1.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.3	0.8	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.2	0.7	GO:0008215	spermine metabolic process(GO:0008215)
0.2	0.7	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.2	0.7	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.2	0.7	GO:0030210	heparin biosynthetic process(GO:0030210)
0.2	0.6	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	0.6	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.2	0.8	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.2	0.6	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.2	0.2	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.2	1.3	GO:0060216	definitive hemopoiesis(GO:0060216)
0.2	0.5	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.2	1.2	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.2	0.3	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.2	0.8	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	0.3	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.2	0.5	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.2	1.1	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.2	0.3	GO:0061117	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.2	0.5	GO:0060677	ureteric bud elongation(GO:0060677)
0.1	0.4	GO:0048539	bone marrow development(GO:0048539)
0.1	0.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.4	GO:0051451	myoblast migration(GO:0051451)
0.1	0.7	GO:0007619	courtship behavior(GO:0007619)
0.1	0.4	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.3	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.1	0.6	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1	0.5	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	0.5	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	1.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.2	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1	0.6	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.1	0.6	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.5	GO:0001757	somite specification(GO:0001757)
0.1	0.3	GO:0060676	ureteric bud formation(GO:0060676)
0.1	0.5	GO:0034393	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	0.6	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.4	GO:0048840	otolith development(GO:0048840)
0.1	0.3	GO:0003323	type B pancreatic cell development(GO:0003323)
0.1	0.3	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.3	GO:0007412	axon target recognition(GO:0007412)
0.1	0.3	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.3	GO:0010159	specification of organ position(GO:0010159)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.1	0.3	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1	0.4	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.1	0.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.6	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.1	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.4	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.1	0.2	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.4	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.1	0.7	GO:0007413	axonal fasciculation(GO:0007413)
0.1	0.6	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.1	0.5	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.4	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1	0.7	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.3	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.2	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.2	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	0.1	GO:0072070	loop of Henle development(GO:0072070)
0.1	0.3	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.2	GO:0008354	germ cell migration(GO:0008354)
0.1	0.4	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1	0.5	GO:0008228	opsonization(GO:0008228)
0.1	0.3	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.5	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1	0.1	GO:0072189	ureter development(GO:0072189) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.1	0.4	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.1	1.0	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.1	0.2	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1	0.1	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.1	0.3	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.3	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.1	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.1	GO:0031033	myosin filament organization(GO:0031033)
0.1	0.4	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	0.3	GO:0008218	bioluminescence(GO:0008218)
0.1	0.4	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.1	0.2	GO:0010842	retina layer formation(GO:0010842)
0.1	0.2	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.1	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1	0.2	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.1	0.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.2	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1	0.4	GO:0098810	neurotransmitter reuptake(GO:0098810)
0.1	0.2	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.2	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.3	GO:0060039	pericardium development(GO:0060039)
0.1	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.2	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.1	0.1	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.1	0.1	GO:0010659	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.2	GO:0060061	Spemann organizer formation(GO:0060061)
0.1	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.6	GO:0042474	middle ear morphogenesis(GO:0042474)
0.1	0.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	1.0	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:2000831	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0	0.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.3	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.2	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.3	GO:0035065	regulation of histone acetylation(GO:0035065) regulation of protein acetylation(GO:1901983) regulation of peptidyl-lysine acetylation(GO:2000756)
0.0	0.1	GO:2000144	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.2	GO:0090177	establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0	0.1	GO:0014059	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.2	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.2	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.4	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.1	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.6	GO:0046697	decidualization(GO:0046697)
0.0	0.2	GO:0043649	dicarboxylic acid catabolic process(GO:0043649)
0.0	0.1	GO:0015824	proline transport(GO:0015824)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.6	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.2	GO:1900087	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.1	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.0	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:0034390	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.2	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.5	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.6	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0032652	regulation of interleukin-1 production(GO:0032652)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.3	GO:0050746	regulation of lipoprotein metabolic process(GO:0050746)
0.0	0.2	GO:0016246	RNA interference(GO:0016246)
0.0	0.2	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	0.2	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.8	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.0	GO:0072311	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.3	GO:0061515	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.1	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.2	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.2	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.0	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.2	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	1.5	GO:0030198	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.1	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.3	GO:0006972	hyperosmotic response(GO:0006972)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.2	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0009264	deoxyribonucleotide catabolic process(GO:0009264)
0.0	0.2	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.2	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0001779	natural killer cell differentiation(GO:0001779) regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.2	GO:0045176	apical protein localization(GO:0045176)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0014002	astrocyte development(GO:0014002)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.1	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.2	GO:0002076	osteoblast development(GO:0002076)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0090266	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.2	GO:0051058	negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.1	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.2	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.6	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.0	GO:0007442	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.6	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.0	0.5	GO:0014032	neural crest cell development(GO:0014032)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.0	GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.2	GO:0046040	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.2	GO:0030201	heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0	0.0	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.9	GO:0019233	sensory perception of pain(GO:0019233)
0.0	0.1	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.1	GO:0034405	response to fluid shear stress(GO:0034405)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.3	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.0	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.1	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.0	GO:0010922	positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.1	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.1	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.0	0.0	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.2	GO:0043113	receptor clustering(GO:0043113)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.2	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.2	GO:0008038	neuron recognition(GO:0008038)
0.0	0.0	GO:0007379	segment specification(GO:0007379)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0002068	glandular epithelial cell development(GO:0002068)
0.0	0.0	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.1	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.0	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.4	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.2	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.1	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.1	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.0	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.2	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
0.0	0.0	GO:0060911	cardiac cell fate commitment(GO:0060911)
0.0	0.3	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0042723	thiamine-containing compound metabolic process(GO:0042723)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.0	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.0	GO:0097576	vacuole fusion(GO:0097576)
0.0	2.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.2	GO:0046135	pyrimidine nucleoside catabolic process(GO:0046135)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.0	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.0	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.3	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.1	GO:0009948	anterior/posterior axis specification(GO:0009948)
0.0	0.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.0	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.0	GO:0048318	axial mesoderm development(GO:0048318)
0.0	0.0	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.1	GO:0050432	catecholamine secretion(GO:0050432)
0.0	0.3	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.0	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.2	GO:0016079	synaptic vesicle exocytosis(GO:0016079)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.0	GO:0033504	floor plate development(GO:0033504)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.9	GO:0007626	locomotory behavior(GO:0007626)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.0	GO:0007512	adult heart development(GO:0007512)
0.0	0.3	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.0	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.0	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.3	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.1	GO:0045916	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.2	GO:0050715	positive regulation of cytokine secretion(GO:0050715)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.1	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.0	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.0	1.0	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.2	GO:0008210	estrogen metabolic process(GO:0008210)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.1	GO:0098743	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.3	GO:1900046	regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.0	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.0	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.0	0.0	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.0	GO:0032106	positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.2	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.1	GO:0048265	response to pain(GO:0048265)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.2	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.0	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.0	GO:0021532	neural tube patterning(GO:0021532)
0.0	0.0	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0001967	suckling behavior(GO:0001967)
0.0	1.5	GO:0006936	muscle contraction(GO:0006936)
0.0	0.0	GO:0008347	glial cell migration(GO:0008347)
0.0	0.0	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0031670	cellular response to nutrient(GO:0031670)
0.0	0.0	GO:0046636	negative regulation of alpha-beta T cell activation(GO:0046636)
0.0	0.0	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.0	GO:0001974	blood vessel remodeling(GO:0001974)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.0	0.0	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.0	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.1	GO:0001759	organ induction(GO:0001759)
0.0	0.0	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.0	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.0	GO:0001706	endoderm formation(GO:0001706)
0.0	0.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0021885	forebrain cell migration(GO:0021885)
0.0	0.1	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0044803	multi-organism membrane organization(GO:0044803)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	0.5	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.2	1.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	0.6	GO:0030934	anchoring collagen complex(GO:0030934)
0.2	0.6	GO:0005588	collagen type V trimer(GO:0005588)
0.2	1.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.5	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.4	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.8	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.7	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.6	GO:0030673	axolemma(GO:0030673)
0.1	0.7	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.3	GO:0032059	bleb(GO:0032059)
0.1	0.2	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.2	GO:0070852	cell body fiber(GO:0070852)
0.1	1.0	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1	0.4	GO:0016589	NURF complex(GO:0016589)
0.1	0.5	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.5	GO:0002102	podosome(GO:0002102)
0.1	0.4	GO:0010369	chromocenter(GO:0010369)
0.1	0.3	GO:0000801	central element(GO:0000801)
0.1	0.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.2	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.1	0.5	GO:0008091	spectrin(GO:0008091)
0.1	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.2	GO:0045298	tubulin complex(GO:0045298)
0.0	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)
0.0	3.3	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	1.1	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.3	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.3	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.5	GO:0005581	collagen trimer(GO:0005581)
0.0	1.9	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.3	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.3	GO:0030897	HOPS complex(GO:0030897)
0.0	2.3	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.4	GO:0044420	extracellular matrix component(GO:0044420)
0.0	0.8	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0001939	female pronucleus(GO:0001939)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.0	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	2.2	GO:0005925	focal adhesion(GO:0005925)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.7	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.5	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.9	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	1.0	GO:0030027	lamellipodium(GO:0030027)
0.0	3.5	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.9	GO:0030426	growth cone(GO:0030426)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.4	GO:0030018	Z disc(GO:0030018)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.0	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0016235	aggresome(GO:0016235)
0.0	1.3	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.3	GO:0030666	endocytic vesicle membrane(GO:0030666)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.3	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.0	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0070069	cytochrome complex(GO:0070069)
0.0	0.7	GO:0043296	apical junction complex(GO:0043296)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.5	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.8	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3	0.9	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	0.7	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2	0.6	GO:0050682	AF-2 domain binding(GO:0050682)
0.2	0.7	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2	0.5	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.2	0.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.2	0.5	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	0.4	GO:0050693	LBD domain binding(GO:0050693)
0.1	1.5	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	0.4	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.5	GO:0050815	phosphoserine binding(GO:0050815)
0.1	0.4	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.8	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.5	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	1.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.8	GO:0005499	vitamin D binding(GO:0005499)
0.1	1.0	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.5	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.4	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.8	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.9	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.7	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.4	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.7	GO:0019966	interleukin-1 binding(GO:0019966)
0.1	0.1	GO:0070052	collagen V binding(GO:0070052)
0.1	0.3	GO:0035198	miRNA binding(GO:0035198)
0.1	0.7	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.7	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	1.3	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.2	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.6	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.4	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	0.4	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.1	0.6	GO:0030507	spectrin binding(GO:0030507)
0.1	0.5	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	0.3	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.9	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.4	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.3	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1	0.5	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.4	GO:0031491	nucleosome binding(GO:0031491)
0.1	0.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.7	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.3	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.1	0.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.2	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	1.1	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.1	1.0	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.8	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1	0.4	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.1	0.9	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	0.5	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	0.7	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	0.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.7	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	0.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	1.8	GO:0005518	collagen binding(GO:0005518)
0.1	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.2	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	1.0	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.3	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.5	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.5	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.2	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	2.8	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.2	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	2.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.2	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.2	GO:0051378	serotonin binding(GO:0051378)
0.0	0.3	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.3	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.7	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.3	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.0	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.0	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.2	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.0	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.1	GO:0008066	glutamate receptor activity(GO:0008066)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.1	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.0	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.3	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.0	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.0	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.0	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.0	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.3	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.0	GO:0008493	tetracycline transporter activity(GO:0008493)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.0	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.2	GO:0070888	E-box binding(GO:0070888)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.0	GO:0001848	complement binding(GO:0001848)
0.0	1.1	GO:0005179	hormone activity(GO:0005179)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.4	GO:0005178	integrin binding(GO:0005178)
0.0	1.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.0	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.1	1.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	4.1	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	0.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.0	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.9	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.3	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.2	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.3	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	4.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	3.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	2.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.2	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.6	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.3	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.2	1.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.9	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	0.9	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	1.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	4.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	2.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.8	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	0.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	0.3	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	0.9	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	0.8	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	0.9	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	0.6	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.1	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.6	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.1	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.4	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.4	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.2	REACTOME PI3K EVENTS IN ERBB4 SIGNALING	Genes involved in PI3K events in ERBB4 signaling
0.0	0.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.8	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.0	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.1	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism

Results for POU5F1_POU2F3

Z-value: 2.87

Motif logo

Transcription factors associated with POU5F1_POU2F3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the POU5F1_POU2F3 motif across conditions

Conditions sorted by the z-value of the POU5F1_POU2F3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: