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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PPARA

Z-value: 0.51

Motif logo

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Transcription factors associated with PPARA

Gene Symbol Gene ID Gene Info
PPARA
ENSG00000186951.12 PPARA

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
PPARAchr22_46544853_4654500414960.306121-0.324.0e-01Click!
PPARAchr22_46568570_4656872140000.183062-0.294.5e-01Click!
PPARAchr22_46544170_4654432121790.2217450.274.8e-01Click!
PPARAchr22_46569183_4656933433870.1964730.264.9e-01Click!
PPARAchr22_46546744_465478964670.7479160.255.1e-01Click!

Activity of the PPARA motif across conditions

Conditions sorted by the z-value of the PPARA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_60273912_60274168 0.15 BICC1
 bicaudal C homolog 1 (Drosophila)
 1140
 0.65
chr6_24743331_24743534 0.13 C6orf62
 chromosome 6 open reading frame 62
 22368
 0.12
chr16_89990293_89990742 0.13 TUBB3
 Tubulin beta-3 chain
 743
 0.44
chr16_70718792_70718985 0.12 MTSS1L
 metastasis suppressor 1-like
 1081
 0.43
chr13_114864635_114864856 0.12 RASA3-IT1
 RASA3 intronic transcript 1 (non-protein coding)
 9550
 0.23
chr14_55117584_55117850 0.11 SAMD4A
 sterile alpha motif domain containing 4A
 83080
 0.09
chr11_789656_789830 0.11 CEND1
 cell cycle exit and neuronal differentiation 1
 380
 0.63
chr4_157805304_157805513 0.10 PDGFC
 platelet derived growth factor C
 33984
 0.18
chr6_11795100_11795449 0.10 ADTRP
 androgen-dependent TFPI-regulating protein
 12005
 0.28
chr5_169172915_169173066 0.10 DOCK2
 dedicator of cytokinesis 2
 13731
 0.24
chr15_60688043_60688242 0.10 ANXA2
 annexin A2
 1395
 0.54
chr19_44139197_44139620 0.10 CADM4
 cell adhesion molecule 4
 4583
 0.1
chr11_130319616_130319897 0.09 ADAMTS15
 ADAM metallopeptidase with thrombospondin type 1 motif, 15
 887
 0.67
chr12_56513564_56513771 0.09 RP11-603J24.6
56
 0.9
chr17_13265618_13265967 0.09 ENSG00000266115
 .
 137853
 0.05
chr10_123871979_123872182 0.09 TACC2
 transforming, acidic coiled-coil containing protein 2
 474
 0.88
chr17_41478521_41478741 0.09 ARL4D
 ADP-ribosylation factor-like 4D
 2304
 0.18
chr9_132429402_132429765 0.09 PRRX2
 paired related homeobox 2
 1663
 0.28
chr4_17782468_17782786 0.09 FAM184B
 family with sequence similarity 184, member B
 508
 0.81
chr4_184797459_184798247 0.09 STOX2
 storkhead box 2
 28656
 0.22
chr1_227503732_227504041 0.09 CDC42BPA
 CDC42 binding protein kinase alpha (DMPK-like)
 997
 0.69
chr5_90458282_90458577 0.09 ENSG00000199643
 .
 108115
 0.08
chr3_159745160_159745451 0.09 LINC01100
 long intergenic non-protein coding RNA 1100
 11494
 0.19
chr20_43973524_43973810 0.08 SDC4
 syndecan 4
 3397
 0.15
chr15_48010788_48011252 0.08 SEMA6D
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
 334
 0.93
chr5_93222742_93222901 0.08 RP11-549J18.1
23290
 0.26
chr13_43843656_43843899 0.08 ENOX1
 ecto-NOX disulfide-thiol exchanger 1
 91436
 0.1
chr12_56236252_56236458 0.08 MMP19
 matrix metallopeptidase 19
 351
 0.76
chr3_12330541_12330692 0.08 PPARG
 peroxisome proliferator-activated receptor gamma
 46
 0.99
chr12_110720958_110721647 0.08 ATP2A2
 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
 1816
 0.41
chr3_134091064_134091340 0.08 AMOTL2
 angiomotin like 2
 448
 0.85
chr12_118745072_118745584 0.08 TAOK3
 TAO kinase 3
 51464
 0.15
chr17_19967741_19968028 0.08 SPECC1
 sperm antigen with calponin homology and coiled-coil domains 1
 22450
 0.18
chr1_156092284_156092708 0.08 LMNA
 lamin A/C
 3455
 0.14
chr4_41215270_41215769 0.08 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 956
 0.59
chr1_119522601_119522807 0.08 TBX15
 T-box 15
 7724
 0.28
chrX_74967065_74967404 0.08 MAGEE2
 melanoma antigen family E, 2
 37845
 0.23
chr6_147236233_147236440 0.08 STXBP5-AS1
 STXBP5 antisense RNA 1
 685
 0.82
chr13_52163965_52164370 0.08 ENSG00000206920
 .
 3499
 0.16
chr15_30112674_30113382 0.08 TJP1
 tight junction protein 1
 723
 0.64
chr10_30238566_30238767 0.08 KIAA1462
 KIAA1462
 109787
 0.07
chr5_98397075_98397538 0.07 ENSG00000200351
 .
 124855
 0.06
chr16_85205463_85205676 0.07 CTC-786C10.1
687
 0.76
chr9_113341179_113342041 0.07 SVEP1
 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
 213
 0.96
chr3_48646099_48647042 0.07 UQCRC1
 ubiquinol-cytochrome c reductase core protein I
 900
 0.38
chr11_62162542_62162710 0.07 CTD-2531D15.5
1782
 0.23
chr4_146018335_146018486 0.07 ANAPC10
 anaphase promoting complex subunit 10
 124
 0.9
chr2_216298275_216298426 0.07 FN1
 fibronectin 1
 2440
 0.3
chr9_104248314_104249564 0.07 TMEM246
 transmembrane protein 246
 460
 0.79
chr6_81974819_81975050 0.07 RP1-300G12.2
269696
 0.02
chr2_227590884_227591406 0.07 ENSG00000263363
 .
 67636
 0.11
chr10_105610252_105610446 0.07 SH3PXD2A
 SH3 and PX domains 2A
 4815
 0.22
chr1_163040363_163040678 0.07 RGS4
 regulator of G-protein signaling 4
 1314
 0.56
chr8_99956690_99957063 0.07 OSR2
 odd-skipped related transciption factor 2
 11
 0.97
chr22_46471692_46472277 0.07 FLJ27365
 hsa-mir-4763
 4208
 0.11
chr17_13503336_13503489 0.07 HS3ST3A1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
 1832
 0.45
chr3_50194015_50194506 0.07 RP11-493K19.3
742
 0.47
chr15_35014576_35014814 0.07 GJD2
 gap junction protein, delta 2, 36kDa
 32471
 0.16
chr7_95545859_95546042 0.07 DYNC1I1
 dynein, cytoplasmic 1, intermediate chain 1
 112354
 0.07
chr1_120191467_120191618 0.07 ZNF697
 zinc finger protein 697
 1146
 0.52
chr19_3384704_3384855 0.07 NFIC
 nuclear factor I/C (CCAAT-binding transcription factor)
 18195
 0.16
chr2_190075356_190075623 0.07 COL5A2
 collagen, type V, alpha 2
 30884
 0.2
chr4_17809379_17809707 0.07 DCAF16
 DDB1 and CUL4 associated factor 16
 2838
 0.25
chr17_15181945_15182253 0.07 PMP22
 peripheral myelin protein 22
 13456
 0.14
chr1_27357912_27358708 0.07 FAM46B
 family with sequence similarity 46, member B
 18983
 0.16
chr7_73443076_73443679 0.07 ELN
 elastin
 859
 0.62
chr2_208378036_208378402 0.07 CREB1
 cAMP responsive element binding protein 1
 16242
 0.2
chr8_74333530_74333818 0.07 RP11-434I12.2
64978
 0.13
chrX_3204067_3204297 0.07 CXorf28
 chromosome X open reading frame 28
 14321
 0.25
chr18_52968140_52968291 0.07 TCF4
 transcription factor 4
 1642
 0.52
chr1_240760678_240760859 0.07 RP11-467I20.6
6720
 0.21
chr1_20125793_20126331 0.07 TMCO4
 transmembrane and coiled-coil domains 4
 225
 0.92
chr17_79315981_79316442 0.07 TMEM105
 transmembrane protein 105
 11737
 0.13
chr4_81198150_81198317 0.07 FGF5
 fibroblast growth factor 5
 10440
 0.25
chr6_58148368_58148782 0.07 ENSG00000212017
 .
 893645
 0.0
chr7_15601189_15601685 0.07 AGMO
 alkylglycerol monooxygenase
 203
 0.97
chr17_1666629_1666885 0.07 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
 634
 0.58
chr13_100752699_100753069 0.07 PCCA
 propionyl CoA carboxylase, alpha polypeptide
 11547
 0.27
chr10_130991187_130991568 0.07 MGMT
 O-6-methylguanine-DNA methyltransferase
 274071
 0.02
chr3_149374923_149375174 0.07 WWTR1
 WW domain containing transcription regulator 1
 174
 0.54
chr11_77733968_77734525 0.07 KCTD14
 potassium channel tetramerization domain containing 14
 94
 0.72
chr6_27205685_27206711 0.07 PRSS16
 protease, serine, 16 (thymus)
 9282
 0.19
chr15_68573463_68573639 0.07 FEM1B
 fem-1 homolog b (C. elegans)
 1254
 0.47
chr1_109247037_109247211 0.07 FNDC7
 fibronectin type III domain containing 7
 8155
 0.16
chr3_15677814_15677988 0.07 BTD
 biotinidase
 34425
 0.13
chr3_69888019_69888170 0.07 MITF
 microphthalmia-associated transcription factor
 27269
 0.22
chr3_16939119_16939271 0.07 PLCL2
 phospholipase C-like 2
 12743
 0.25
chr3_194592423_194592920 0.07 FAM43A
 family with sequence similarity 43, member A
 186049
 0.02
chr17_46561109_46561276 0.06 ENSG00000206805
 .
 4733
 0.14
chr10_99441863_99442014 0.06 AVPI1
 arginine vasopressin-induced 1
 5142
 0.16
chr5_144624994_144625233 0.06 ENSG00000221467
 .
 47775
 0.2
chr15_96883153_96883304 0.06 ENSG00000222651
 .
 6738
 0.16
chr17_72868164_72868332 0.06 FDXR
 ferredoxin reductase
 838
 0.46
chr2_175863049_175863322 0.06 CHN1
 chimerin 1
 6769
 0.16
chr8_145022099_145022649 0.06 PLEC
 plectin
 1659
 0.22
chr4_166252557_166253372 0.06 MSMO1
 methylsterol monooxygenase 1
 3885
 0.25
chr20_10650822_10650973 0.06 RP11-103J8.1
2679
 0.32
chr3_8544328_8544516 0.06 LMCD1
 LIM and cysteine-rich domains 1
 850
 0.49
chr16_75150295_75150455 0.06 LDHD
 lactate dehydrogenase D
 290
 0.87
chr4_138531037_138531225 0.06 PCDH18
 protocadherin 18
 77483
 0.13
chr9_132949373_132949609 0.06 NCS1
 neuronal calcium sensor 1
 13381
 0.21
chrX_11456012_11456286 0.06 ARHGAP6
 Rho GTPase activating protein 6
 10256
 0.3
chr17_3379575_3379800 0.06 ASPA
 aspartoacylase
 391
 0.8
chr1_157980874_157981318 0.06 KIRREL-IT1
 KIRREL intronic transcript 1 (non-protein coding)
 14244
 0.2
chr8_32406806_32407051 0.06 NRG1
 neuregulin 1
 683
 0.82
chr1_113931913_113932064 0.06 MAGI3
 membrane associated guanylate kinase, WW and PDZ domain containing 3
 1383
 0.6
chr15_74232964_74233156 0.06 LOXL1-AS1
 LOXL1 antisense RNA 1
 12471
 0.14
chr15_52859194_52859345 0.06 ARPP19
 cAMP-regulated phosphoprotein, 19kDa
 1760
 0.33
chr19_48991098_48991290 0.06 CYTH2
 cytohesin 2
 15585
 0.09
chr10_93373658_93374073 0.06 PPP1R3C
 protein phosphatase 1, regulatory subunit 3C
 18946
 0.27
chr12_110210896_110211119 0.06 FAM222A-AS1
 FAM222A antisense RNA 1
 282
 0.9
chr8_122648522_122648761 0.06 HAS2-AS1
 HAS2 antisense RNA 1
 2892
 0.31
chr17_74697030_74697413 0.06 ENSG00000212418
 .
 2588
 0.13
chr11_95888990_95889540 0.06 ENSG00000266192
 .
 185337
 0.03
chr3_184037306_184037783 0.06 EIF4G1
 eukaryotic translation initiation factor 4 gamma, 1
 1
 0.95
chr20_54919132_54919450 0.06 FAM210B
 family with sequence similarity 210, member B
 14680
 0.17
chrX_115085279_115085526 0.06 ENSG00000266828
 .
 23698
 0.24
chr3_167780902_167781122 0.06 GOLIM4
 golgi integral membrane protein 4
 32120
 0.24
chr13_52164714_52165080 0.06 ENSG00000242893
 .
 3454
 0.16
chr16_30081137_30081369 0.06 ALDOA
 aldolase A, fructose-bisphosphate
 354
 0.71
chr1_41176173_41176466 0.06 NFYC
 nuclear transcription factor Y, gamma
 1104
 0.44
chr9_71746233_71746472 0.06 TJP2
 tight junction protein 2
 10128
 0.26
chr6_7468590_7468920 0.06 RP3-512B11.3
72816
 0.09
chr6_170053828_170054109 0.06 WDR27
 WD repeat domain 27
 6820
 0.18
chr6_17283021_17283300 0.06 RBM24
 RNA binding motif protein 24
 228
 0.96
chr6_26780154_26780414 0.06 GUSBP2
 glucuronidase, beta pseudogene 2
 66333
 0.11
chr3_143568633_143568784 0.06 SLC9A9
 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
 1335
 0.61
chr7_101579659_101580126 0.06 CTB-181H17.1
23504
 0.22
chr11_707284_707470 0.06 EPS8L2
 EPS8-like 2
 748
 0.42
chr2_42599068_42599219 0.06 COX7A2L
 cytochrome c oxidase subunit VIIa polypeptide 2 like
 2993
 0.32
chr7_116141667_116142184 0.06 CAV2
 caveolin 2
 2091
 0.24
chr4_26789379_26789589 0.06 STIM2
 stromal interaction molecule 2
 69816
 0.11
chr5_17359988_17360246 0.06 ENSG00000201715
 .
 14392
 0.27
chr3_116755540_116755902 0.06 ENSG00000200372
 .
 71647
 0.12
chr10_30346435_30346778 0.06 KIAA1462
 KIAA1462
 1847
 0.5
chr14_86002689_86002854 0.06 FLRT2
 fibronectin leucine rich transmembrane protein 2
 6199
 0.26
chr6_106049688_106050083 0.06 PREP
 prolyl endopeptidase
 198926
 0.03
chr6_21808747_21809320 0.06 SOX4
 SRY (sex determining region Y)-box 4
 214962
 0.02
chr1_162601787_162601952 0.06 DDR2
 discoidin domain receptor tyrosine kinase 2
 68
 0.98
chr6_158252834_158252985 0.06 RP11-52J3.3
1304
 0.44
chr11_118492062_118492969 0.06 PHLDB1
 pleckstrin homology-like domain, family B, member 1
 14157
 0.11
chr7_17719632_17719796 0.06 SNX13
 sorting nexin 13
 260377
 0.02
chr6_28641788_28642196 0.06 ENSG00000272278
 .
 25950
 0.18
chr15_74724718_74725429 0.06 SEMA7A
 semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
 928
 0.5
chr6_26721817_26722019 0.06 ZNF322
 zinc finger protein 322
 61938
 0.11
chr21_35133624_35133954 0.06 ITSN1
 intersectin 1 (SH3 domain protein)
 26443
 0.2
chr8_19148668_19149118 0.06 SH2D4A
 SH2 domain containing 4A
 22235
 0.28
chr1_119524620_119524878 0.06 TBX15
 T-box 15
 5679
 0.29
chr2_181849023_181849317 0.06 UBE2E3
 ubiquitin-conjugating enzyme E2E 3
 2420
 0.35
chr5_102202832_102203172 0.06 PAM
 peptidylglycine alpha-amidating monooxygenase
 1182
 0.66
chr6_27584810_27585278 0.06 ENSG00000238648
 .
 14144
 0.19
chr19_17797231_17797557 0.06 UNC13A
 unc-13 homolog A (C. elegans)
 1614
 0.31
chr4_30722001_30722807 0.06 PCDH7
 protocadherin 7
 367
 0.93
chr6_150465056_150465588 0.06 PPP1R14C
 protein phosphatase 1, regulatory (inhibitor) subunit 14C
 1110
 0.53
chr1_12124202_12124372 0.06 TNFRSF8
 tumor necrosis factor receptor superfamily, member 8
 760
 0.56
chr19_47366981_47367578 0.06 AP2S1
 adaptor-related protein complex 2, sigma 1 subunit
 13030
 0.17
chr7_66532196_66532424 0.06 ENSG00000266525
 .
 47074
 0.12
chr7_15723868_15724269 0.06 MEOX2
 mesenchyme homeobox 2
 2369
 0.37
chr12_96593279_96593430 0.06 ELK3
 ELK3, ETS-domain protein (SRF accessory protein 2)
 4962
 0.23
chr17_76879212_76879961 0.06 TIMP2
 TIMP metallopeptidase inhibitor 2
 9354
 0.14
chr12_52404839_52404990 0.06 GRASP
 GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
 53
 0.96
chr1_164724851_164725042 0.06 PBX1
 pre-B-cell leukemia homeobox 1
 17203
 0.18
chr1_16030367_16030679 0.06 ENSG00000264048
 .
 19556
 0.09
chr12_54417118_54417269 0.06 HOXC6
 homeobox C6
 4949
 0.07
chr6_27258471_27258730 0.06 POM121L2
 POM121 transmembrane nucleoporin-like 2
 20491
 0.18
chr4_20447726_20447877 0.06 SLIT2-IT1
 SLIT2 intronic transcript 1 (non-protein coding)
 53989
 0.15
chr4_56731523_56731723 0.06 EXOC1
 exocyst complex component 1
 11718
 0.19
chr11_8832007_8832297 0.06 ST5
 suppression of tumorigenicity 5
 44
 0.97
chr6_116571521_116571672 0.06 TSPYL4
 TSPY-like 4
 3665
 0.18
chr1_161992740_161992891 0.06 OLFML2B
 olfactomedin-like 2B
 615
 0.79
chr1_8772875_8773203 0.06 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 9761
 0.25
chr5_11903634_11904112 0.06 CTNND2
 catenin (cadherin-associated protein), delta 2
 237
 0.97
chr1_234792015_234792239 0.06 IRF2BP2
 interferon regulatory factor 2 binding protein 2
 46856
 0.14
chr5_87436294_87437103 0.06 TMEM161B
 transmembrane protein 161B
 79750
 0.11
chr12_57611971_57612122 0.06 NXPH4
 neurexophilin 4
 1468
 0.23
chr12_15049535_15049773 0.06 MGP
 matrix Gla protein
 10794
 0.15
chr2_67601751_67601914 0.06 ETAA1
 Ewing tumor-associated antigen 1
 22619
 0.29
chr11_6341290_6341712 0.06 PRKCDBP
 protein kinase C, delta binding protein
 261
 0.9
chr8_132869766_132869917 0.06 EFR3A
 EFR3 homolog A (S. cerevisiae)
 46494
 0.2
chr5_53765392_53765543 0.06 HSPB3
 heat shock 27kDa protein 3
 14022
 0.25
chr2_3699150_3699650 0.06 ALLC
 allantoicase
 6385
 0.16
chr17_2869341_2869540 0.06 CTD-3060P21.1
251
 0.94
chr8_71580499_71580692 0.06 LACTB2
 lactamase, beta 2
 797
 0.44
chr19_11203405_11203676 0.06 LDLR
 low density lipoprotein receptor
 2265
 0.24
chr12_58819523_58819907 0.06 RP11-362K2.2
 Protein LOC100506869
 118192
 0.06
chr5_158520357_158520666 0.05 EBF1
 early B-cell factor 1
 6190
 0.27
chr8_32407781_32407984 0.05 NRG1
 neuregulin 1
 1637
 0.54
chr16_89392054_89392556 0.05 AC137932.6
2673
 0.19
chr15_96879714_96879865 0.05 ENSG00000222651
 .
 3299
 0.19
chr6_27462859_27463076 0.05 ZNF184
 zinc finger protein 184
 22070
 0.21
chr8_27492286_27492503 0.05 SCARA3
 scavenger receptor class A, member 3
 696
 0.66
chrX_102940107_102940387 0.05 MORF4L2
 mortality factor 4 like 2
 902
 0.43
chr7_151433344_151433930 0.05 PRKAG2
 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
 237
 0.95
chr10_4813272_4813482 0.05 AKR1E2
 aldo-keto reductase family 1, member E2
 15444
 0.27
chr1_161168438_161168589 0.05 ADAMTS4
 ADAM metallopeptidase with thrombospondin type 1 motif, 4
 330
 0.57
chr17_6451663_6451961 0.05 PITPNM3
 PITPNM family member 3
 7968
 0.17
chr18_77746974_77747125 0.05 TXNL4A
 thioredoxin-like 4A
 1488
 0.39
chr10_33248964_33249203 0.05 ITGB1
 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 1923
 0.46
chr22_38145954_38146139 0.05 TRIOBP
 TRIO and F-actin binding protein
 958
 0.43
chr7_101525780_101526170 0.05 CTA-339C12.1
57966
 0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PPARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.0 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0090026 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.0 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0046980 tapasin binding(GO:0046980)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo