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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PRDM1

Z-value: 4.18

Motif logo

Transcription factors associated with PRDM1

Gene Symbol	Gene ID	Gene Info
PRDM1 Ensembl NCBI GeneCards UniProt	ENSG00000057657.10	PRDM1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
PRDM1	chr6_106474855_106475295	59120	0.133971	0.49	1.8e-01	Click!
PRDM1	chr6_106531584_106531735	2536	0.337820	0.44	2.4e-01	Click!
PRDM1	chr6_106533592_106533944	427	0.872279	0.41	2.7e-01	Click!
PRDM1	chr6_106445374_106445525	88746	0.084201	0.40	2.8e-01	Click!
PRDM1	chr6_106542111_106542262	4295	0.259146	0.39	3.0e-01	Click!

Activity of the PRDM1 motif across conditions

Conditions sorted by the z-value of the PRDM1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_15390844_15391029	2.55	FAM171A1	family with sequence similarity 171, member A1	22122	0.25
chr10_52984247_52984441	1.96	RP11-40C11.2		21222	0.19
chr17_78044749_78045392	1.83	CCDC40	coiled-coil domain containing 40	12346	0.15
chr18_40710046_40710304	1.62	RIT2	Ras-like without CAAX 2	14518	0.31
chr16_65566073_65566543	1.59	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	410040	0.01
chr2_40506166_40506540	1.53	AC007377.1		18206	0.24
chr6_151392247_151392482	1.43	RP1-292B18.3		15171	0.18
chr10_61927237_61927410	1.34	ANK3	ankyrin 3, node of Ranvier (ankyrin G)	669	0.8
chr4_99468302_99468540	1.34	RP11-724M22.1		50906	0.16
chr8_58660875_58661197	1.33	ENSG00000252057	.	191892	0.03
chr13_21289085_21289250	1.33	ENSG00000265710	.	11325	0.19
chr6_131290698_131290904	1.31	EPB41L2	erythrocyte membrane protein band 4.1-like 2	822	0.76
chr5_144624790_144624969	1.31	ENSG00000221467	.	47541	0.21
chr2_151343410_151343893	1.28	RND3	Rho family GTPase 3	530	0.88
chr1_163039657_163039882	1.25	RGS4	regulator of G-protein signaling 4	618	0.82
chr11_104788188_104788675	1.25	RP11-693N9.2		7789	0.2
chrX_83618810_83618981	1.23	ENSG00000221494	.	138059	0.05
chr4_160170135_160170337	1.23	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	17797	0.23
chr15_62916920_62917378	1.21	RP11-625H11.1	Uncharacterized protein	20231	0.19
chr7_92325122_92325607	1.21	ENSG00000206763	.	5764	0.28
chr11_2966476_2966712	1.21	PHLDA2	pleckstrin homology-like domain, family A, member 2	15909	0.11
chr8_123256270_123256596	1.21	ENSG00000238901	.	427097	0.01
chr6_6005898_6006049	1.21	NRN1	neuritin 1	1227	0.56
chr13_41013314_41013519	1.21	ENSG00000252812	.	31839	0.22
chr18_7460561_7460853	1.20	PTPRM	protein tyrosine phosphatase, receptor type, M	106073	0.07
chr12_65997242_65997414	1.18	HMGA2	high mobility group AT-hook 2	220583	0.02
chr1_174383473_174383626	1.18	GPR52	G protein-coupled receptor 52	33663	0.21
chr8_134203052_134203203	1.17	WISP1	WNT1 inducible signaling pathway protein 1	155	0.97
chr3_178787859_178788171	1.15	ZMAT3	zinc finger, matrin-type 3	1339	0.48
chr13_34061717_34062025	1.15	STARD13	StAR-related lipid transfer (START) domain containing 13	137104	0.05
chr12_120246787_120247132	1.14	CIT	citron (rho-interacting, serine/threonine kinase 21)	5772	0.26
chr6_132735691_132735842	1.13	MOXD1	monooxygenase, DBH-like 1	13082	0.25
chr3_187755166_187755324	1.13	LPP	LIM domain containing preferred translocation partner in lipoma	115827	0.06
chr11_46307450_46307608	1.13	CREB3L1	cAMP responsive element binding protein 3-like 1	8301	0.18
chr4_126541169_126541320	1.12	FAT4	FAT atypical cadherin 4	226153	0.02
chr11_88914566_88914721	1.10	TYR	tyrosinase	4023	0.33
chr1_116920744_116920998	1.09	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	4162	0.19
chr1_47119420_47119571	1.09	ATPAF1	ATP synthase mitochondrial F1 complex assembly factor 1	4904	0.15
chr2_161808984_161809250	1.07	ENSG00000244372	.	75059	0.12
chr1_201914577_201914874	1.06	LMOD1	leiomodin 1 (smooth muscle)	990	0.39
chr17_17863110_17863392	1.06	TOM1L2	target of myb1-like 2 (chicken)	12460	0.15
chr2_191511664_191511958	1.02	NAB1	NGFI-A binding protein 1 (EGR1 binding protein 1)	339	0.9
chr3_186822986_186823144	1.02	RPL39L	ribosomal protein L39-like	34207	0.17
chr1_180881031_180881376	1.01	KIAA1614	KIAA1614	1122	0.51
chr11_122072907_122073271	1.01	ENSG00000207994	.	50073	0.12
chr9_2126015_2126202	1.01	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	31572	0.18
chr10_30209872_30210248	1.00	KIAA1462	KIAA1462	138393	0.05
chr10_117740714_117740886	1.00	GFRA1	GDNF family receptor alpha 1	274507	0.02
chr2_134484497_134484648	1.00	ENSG00000200708	.	130910	0.05
chr1_219445701_219445873	0.99	RP11-135J2.4		98484	0.08
chr10_116157125_116157362	0.99	AFAP1L2	actin filament associated protein 1-like 2	6996	0.24
chr4_181928076_181928259	0.99	ENSG00000251742	.	828094	0.0
chr4_87503159_87503484	0.98	MAPK10	mitogen-activated protein kinase 10	11942	0.21
chr5_57368325_57368559	0.98	ENSG00000238899	.	2427	0.45
chr11_63713225_63713426	0.98	NAA40	N(alpha)-acetyltransferase 40, NatD catalytic subunit	6605	0.12
chr1_23894994_23895239	0.97	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	8831	0.18
chr1_216692804_216692955	0.97	USH2A	Usher syndrome 2A (autosomal recessive, mild)	96141	0.09
chr14_22848856_22849106	0.97	ENSG00000251002	.	52738	0.09
chr1_71831543_71831741	0.97	ENSG00000229956	.	35763	0.23
chr5_158524974_158525234	0.96	EBF1	early B-cell factor 1	1597	0.48
chr15_83870418_83870820	0.96	HDGFRP3	Hepatoma-derived growth factor-related protein 3	6151	0.19
chr14_55194961_55195128	0.96	SAMD4A	sterile alpha motif domain containing 4A	26507	0.23
chr10_4093321_4093737	0.95	KLF6	Kruppel-like factor 6	266056	0.02
chr6_161860014_161860217	0.95	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4	165022	0.04
chr9_113282590_113282762	0.95	ENSG00000212254	.	19402	0.24
chr12_91533014_91533165	0.95	DCN	decorin	6896	0.25
chr10_121209276_121209427	0.94	GRK5	G protein-coupled receptor kinase 5	71402	0.09
chr5_87798376_87798680	0.94	TMEM161B-AS1	TMEM161B antisense RNA 1	76016	0.11
chr7_116332995_116333296	0.93	MET	met proto-oncogene	5994	0.27
chr12_76376819_76377254	0.93	ENSG00000243420	.	25126	0.18
chr1_243517492_243517644	0.93	ENSG00000265201	.	8090	0.26
chr9_75708779_75709072	0.92	ALDH1A1	aldehyde dehydrogenase 1 family, member A1	13567	0.27
chr5_14449868_14450019	0.92	TRIO	trio Rho guanine nucleotide exchange factor	38614	0.21
chr8_92988247_92988452	0.92	GS1-5L10.1		213	0.96
chr10_90966269_90966420	0.91	CH25H	cholesterol 25-hydroxylase	727	0.67
chr9_112542645_112542955	0.91	AKAP2	A kinase (PRKA) anchor protein 2	31	0.37
chr8_77585853_77586055	0.89	ZFHX4	zinc finger homeobox 4	7500	0.24
chr8_16645234_16645451	0.89	ENSG00000264092	.	75663	0.12
chr7_25835612_25835941	0.89	ENSG00000199085	.	153830	0.04
chr9_18490908_18491217	0.89	ADAMTSL1	ADAMTS-like 1	16831	0.27
chr2_143773567_143773818	0.88	ENSG00000221169	.	10332	0.28
chr5_165798296_165798496	0.88	ENSG00000264903	.	211871	0.03
chr19_55598672_55599034	0.88	EPS8L1	EPS8-like 1	7093	0.1
chr10_124222195_124222452	0.88	HTRA1	HtrA serine peptidase 1	1282	0.44
chr15_49760511_49761130	0.88	FGF7	fibroblast growth factor 7	45363	0.16
chr6_134212007_134212270	0.88	RP3-323P13.2		936	0.53
chr8_122274743_122274894	0.88	ENSG00000221644	.	75686	0.12
chrY_21763188_21763339	0.87	TXLNG2P	taxilin gamma 2, pseudogene	4821	0.27
chr11_14467853_14468182	0.86	ENSG00000251991	.	32421	0.18
chr18_50434264_50434415	0.86	DCC	deleted in colorectal carcinoma	26803	0.22
chr18_53526273_53526597	0.85	TCF4	transcription factor 4	194417	0.03
chr5_78858830_78859073	0.84	ENSG00000207391	.	28275	0.18
chr3_152313885_152314285	0.84	RP11-362A9.3		99483	0.08
chr2_12129216_12129367	0.84	ENSG00000238503	.	41207	0.19
chr6_49294723_49295128	0.84	ENSG00000252457	.	17596	0.27
chr3_145616284_145616545	0.84	RP11-274H2.5		163052	0.04
chr18_53775687_53775874	0.84	ENSG00000201816	.	28955	0.27
chr8_50826499_50826650	0.84	SNTG1	syntrophin, gamma 1	1869	0.53
chr2_98630005_98630391	0.84	TMEM131	transmembrane protein 131	17810	0.24
chr18_67834074_67834322	0.84	RTTN	rotatin	38764	0.21
chr11_131487348_131487499	0.83	NTM	neurotrimin	35518	0.18
chr22_28174315_28174484	0.83	MN1	meningioma (disrupted in balanced translocation) 1	23087	0.23
chr20_49465299_49465721	0.83	ENSG00000265062	.	11935	0.18
chr1_78961568_78961719	0.83	PTGFR	prostaglandin F receptor (FP)	4886	0.31
chr13_32119960_32120148	0.83	RXFP2	relaxin/insulin-like family peptide receptor 2	193620	0.03
chr9_122707486_122707725	0.82	ENSG00000207814	.	299723	0.01
chr11_111445251_111445475	0.82	SIK2	salt-inducible kinase 2	27752	0.11
chr10_131761561_131761767	0.81	EBF3	early B-cell factor 3	441	0.9
chr5_120534956_120535178	0.81	ENSG00000222609	.	488532	0.01
chr2_199480864_199481015	0.81	ENSG00000252511	.	49486	0.2
chr18_53167832_53168083	0.81	RP11-619L19.2		8551	0.19
chr3_121151020_121151375	0.80	POLQ	polymerase (DNA directed), theta	113656	0.06
chr10_34630198_34630349	0.80	PARD3	par-3 family cell polarity regulator	31188	0.25
chrX_99900030_99900181	0.79	SRPX2	sushi-repeat containing protein, X-linked 2	890	0.57
chr6_47165564_47165740	0.79	TNFRSF21	tumor necrosis factor receptor superfamily, member 21	111989	0.07
chr6_88506291_88506649	0.79	ENSG00000207131	.	29533	0.16
chr17_13486518_13486693	0.79	HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	18639	0.23
chr7_16473361_16473576	0.78	ISPD	isoprenoid synthase domain containing	12521	0.23
chrX_83420601_83420752	0.78	RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	22239	0.25
chr8_11349538_11349737	0.78	BLK	B lymphoid tyrosine kinase	1873	0.29
chr2_205920685_205921182	0.78	PARD3B	par-3 family cell polarity regulator beta	510210	0.0
chr14_65273817_65273968	0.77	SPTB	spectrin, beta, erythrocytic	15920	0.19
chr4_87373379_87373575	0.77	MAPK10	mitogen-activated protein kinase 10	806	0.74
chr2_16831792_16832248	0.77	FAM49A	family with sequence similarity 49, member A	15076	0.3
chr6_11231077_11231290	0.77	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	1708	0.44
chr7_132765840_132766055	0.76	CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3	853	0.59
chr4_159574164_159574322	0.76	C4orf46	chromosome 4 open reading frame 46	18801	0.16
chr4_86745352_86745503	0.76	ARHGAP24	Rho GTPase activating protein 24	3471	0.34
chr5_80690086_80690663	0.76	ACOT12	acyl-CoA thioesterase 12	376	0.91
chr14_55796796_55797030	0.76	RP11-665C16.5		9306	0.24
chr2_145753160_145753596	0.76	ENSG00000253036	.	339260	0.01
chr5_102203960_102204196	0.76	PAM	peptidylglycine alpha-amidating monooxygenase	2258	0.46
chr6_12279974_12280135	0.75	EDN1	endothelin 1	10542	0.3
chr4_124776288_124776439	0.75	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	455240	0.01
chr8_95273934_95274493	0.75	GEM	GTP binding protein overexpressed in skeletal muscle	360	0.91
chr18_30310087_30311054	0.75	AC012123.1	Uncharacterized protein	39188	0.17
chr20_44699432_44699601	0.75	NCOA5	nuclear receptor coactivator 5	19075	0.14
chr1_214491340_214491539	0.75	SMYD2	SET and MYND domain containing 2	12881	0.25
chr4_138463714_138463954	0.75	PCDH18	protocadherin 18	10186	0.33
chr17_11852046_11852277	0.75	RP11-1096G20.5		28750	0.16
chr10_4425832_4426362	0.74	ENSG00000207124	.	131047	0.06
chr6_21916023_21916204	0.74	ENSG00000222515	.	169660	0.04
chr8_119115834_119115985	0.74	EXT1	exostosin glycosyltransferase 1	6744	0.34
chr10_51811950_51812150	0.74	RP11-324H6.5		11086	0.19
chr6_99212409_99212624	0.73	POU3F2	POU class 3 homeobox 2	70064	0.14
chr2_199639717_199640158	0.73	ENSG00000252511	.	208484	0.03
chr3_99679363_99679603	0.73	ENSG00000264897	.	3759	0.33
chr21_18376217_18376955	0.72	ENSG00000239023	.	285269	0.01
chr11_43598101_43598272	0.72	ENSG00000199077	.	4758	0.24
chr13_31271674_31272060	0.72	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	37778	0.19
chr11_32383224_32383375	0.72	WT1	Wilms tumor 1	38862	0.19
chr1_208260069_208260332	0.72	PLXNA2	plexin A2	157465	0.04
chr2_52632101_52632252	0.72	ENSG00000202195	.	107043	0.08
chr15_44485809_44485960	0.71	FRMD5	FERM domain containing 5	760	0.75
chr4_140737330_140737550	0.71	ENSG00000252233	.	21853	0.23
chr11_85429919_85430085	0.71	SYTL2	synaptotagmin-like 2	123	0.96
chr8_97505496_97505647	0.71	SDC2	syndecan 2	8	0.99
chr13_102965778_102965929	0.71	FGF14-AS1	FGF14 antisense RNA 1	54036	0.15
chr18_42366702_42366923	0.70	SETBP1	SET binding protein 1	89683	0.1
chr12_68246942_68247109	0.70	IFNG-AS1	IFNG antisense RNA 1	136200	0.05
chr7_84198152_84198303	0.70	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	76187	0.12
chr14_54605059_54605210	0.70	BMP4	bone morphogenetic protein 4	179655	0.03
chr5_54834427_54834797	0.69	PPAP2A	phosphatidic acid phosphatase type 2A	3734	0.27
chr5_111952744_111952991	0.69	APC	adenomatous polyposis coli	90328	0.09
chr1_161932087_161932899	0.69	OLFML2B	olfactomedin-like 2B	22529	0.22
chr11_96438289_96438578	0.69	ENSG00000200411	.	230577	0.02
chr22_40672320_40672471	0.69	TNRC6B	trinucleotide repeat containing 6B	11388	0.23
chr7_19155354_19155672	0.68	TWIST1	twist family bHLH transcription factor 1	1782	0.28
chr1_59522619_59522770	0.68	FGGY	FGGY carbohydrate kinase domain containing	239616	0.02
chr12_76426636_76426787	0.68	PHLDA1	pleckstrin homology-like domain, family A, member 1	1001	0.51
chr9_118917834_118918063	0.68	PAPPA	pregnancy-associated plasma protein A, pappalysin 1	1865	0.44
chr6_170768539_170768975	0.68	RP1-140C12.2		45530	0.15
chr2_128491483_128491650	0.68	SFT2D3	SFT2 domain containing 3	32969	0.13
chr11_88390713_88390864	0.68	ENSG00000207113	.	44709	0.2
chr17_77042563_77042714	0.67	C1QTNF1	C1q and tumor necrosis factor related protein 1	2963	0.2
chr2_136598368_136598551	0.67	LCT	lactase	3709	0.2
chr2_67801375_67801526	0.67	ETAA1	Ewing tumor-associated antigen 1	176999	0.03
chr12_17794706_17795007	0.67	ENSG00000206662	.	69012	0.15
chr10_53627774_53628104	0.67	CSTF2T	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant	168584	0.04
chr1_70916763_70916914	0.67	CTH	cystathionase (cystathionine gamma-lyase)	39772	0.17
chr4_184797459_184798247	0.67	STOX2	storkhead box 2	28656	0.22
chr3_120003475_120003938	0.67	GPR156	G protein-coupled receptor 156	235	0.94
chr15_74657875_74658107	0.66	CTD-2311M21.3		215	0.75
chr5_140430825_140431264	0.66	PCDHB1	protocadherin beta 1	65	0.96
chr4_19264306_19264465	0.66	ENSG00000251816	.	80906	0.12
chr17_56310096_56310247	0.66	LPO	lactoperoxidase	5616	0.14
chr9_110400851_110401256	0.66	ENSG00000202308	.	24474	0.24
chr5_89167593_89167744	0.66	ENSG00000264342	.	144869	0.05
chr6_134494547_134494698	0.65	SGK1	serum/glucocorticoid regulated kinase 1	1380	0.45
chr4_89730559_89730710	0.65	FAM13A	family with sequence similarity 13, member A	13718	0.24
chr18_72509515_72509666	0.65	ZNF407	zinc finger protein 407	166614	0.04
chr5_60599280_60599578	0.65	ZSWIM6	zinc finger, SWIM-type containing 6	28671	0.23
chr1_198092217_198092386	0.65	NEK7	NIMA-related kinase 7	33792	0.24
chr6_128799339_128799870	0.65	RP1-86D1.5		22068	0.14
chr18_19481957_19482108	0.65	ENSG00000252325	.	22270	0.15
chr3_105656990_105657196	0.64	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	68697	0.15
chr20_58004477_58004645	0.64	ENSG00000263903	.	83026	0.09
chr9_80985944_80986319	0.64	PSAT1	phosphoserine aminotransferase 1	74072	0.12
chr7_84292969_84293132	0.64	ENSG00000265050	.	2274	0.47
chr7_105134630_105134781	0.64	PUS7	pseudouridylate synthase 7 homolog (S. cerevisiae)	13877	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.2	0.8	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	0.5	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.3	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.3	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.3	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.3	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.3	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.4	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.3	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.1	0.3	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.2	GO:0060435	bronchiole development(GO:0060435)
0.1	0.2	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.4	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.4	GO:0006726	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.3	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1	0.3	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1	0.8	GO:0031000	response to caffeine(GO:0031000)
0.1	0.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.3	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.5	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.1	0.6	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.6	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.1	0.2	GO:0090195	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.1	0.2	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.9	GO:0014037	Schwann cell differentiation(GO:0014037)
0.1	0.2	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.9	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.1	0.4	GO:0008356	asymmetric cell division(GO:0008356)
0.1	0.2	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1	0.2	GO:0008354	germ cell migration(GO:0008354)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.3	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.1	0.2	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1	0.2	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.3	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1	0.2	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	0.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.3	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.1	0.2	GO:0014824	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1	0.3	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1	0.2	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0052167	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.2	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.6	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.4	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.3	GO:0045047	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.2	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.0	0.2	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.5	GO:0035329	hippo signaling(GO:0035329)
0.0	0.2	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.6	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.3	GO:0006911	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.1	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.2	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.9	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0097531	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:1901889	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0	0.1	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.0	GO:1903670	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0	0.2	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.7	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.1	GO:0002249	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.3	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.6	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.2	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.1	GO:0042819	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.2	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.2	GO:0031529	ruffle organization(GO:0031529)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.2	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.4	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.2	GO:0030903	notochord development(GO:0030903)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.0	GO:0060437	lung growth(GO:0060437)
0.0	0.2	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.3	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0	0.0	GO:0060526	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.5	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.0	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0051883	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.0	GO:0048278	vesicle docking(GO:0048278)
0.0	0.0	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.4	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.0	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0016198	axon choice point recognition(GO:0016198) axon midline choice point recognition(GO:0016199)
0.0	0.3	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.1	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.2	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	1.3	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.2	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	2.4	GO:0006184	obsolete GTP catabolic process(GO:0006184)
0.0	0.1	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.0	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.1	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.5	GO:0042552	myelination(GO:0042552)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0072178	nephric duct morphogenesis(GO:0072178)
0.0	0.0	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.2	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	0.0	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.0	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.0	GO:0033079	immature T cell proliferation(GO:0033079)
0.0	0.1	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.0	GO:0055057	neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0010873	positive regulation of cholesterol esterification(GO:0010873)
0.0	0.0	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.5	GO:0007368	determination of left/right symmetry(GO:0007368)
0.0	0.0	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.1	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.0	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.0	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.0	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	0.1	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure(GO:0003071)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.2	GO:0008542	visual learning(GO:0008542)
0.0	0.1	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.1	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.2	GO:1900076	regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.0	0.0	GO:0021794	thalamus development(GO:0021794)
0.0	0.1	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.0	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.1	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.2	GO:0008038	neuron recognition(GO:0008038)
0.0	0.2	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.0	GO:0045661	regulation of myoblast differentiation(GO:0045661)
0.0	0.0	GO:0097154	GABAergic neuron differentiation(GO:0097154)
0.0	0.0	GO:1903960	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.2	GO:0051693	actin filament capping(GO:0051693)
0.0	0.1	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	GO:0008091	spectrin(GO:0008091)
0.1	0.3	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.3	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.3	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.5	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.2	GO:0043218	compact myelin(GO:0043218)
0.1	0.6	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.2	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.4	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.3	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.4	GO:0030315	T-tubule(GO:0030315)
0.0	0.2	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.7	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.4	GO:0071203	WASH complex(GO:0071203)
0.0	0.2	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.5	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.4	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.5	GO:0045178	basal part of cell(GO:0045178)
0.0	0.1	GO:0044304	main axon(GO:0044304)
0.0	1.5	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.4	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	5.0	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	1.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.3	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	1.2	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.0	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	1.1	GO:0043025	neuronal cell body(GO:0043025)
0.0	0.2	GO:0016234	inclusion body(GO:0016234)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3	0.8	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	0.9	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2	0.6	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.2	0.8	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	1.0	GO:0030507	spectrin binding(GO:0030507)
0.1	0.5	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.7	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	2.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.3	GO:0005113	patched binding(GO:0005113)
0.1	0.3	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.4	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.6	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.3	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	0.2	GO:0048039	ubiquinone binding(GO:0048039)
0.1	0.5	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.6	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.3	GO:0008432	JUN kinase binding(GO:0008432)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.2	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1	0.2	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.1	0.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.2	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	0.7	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.3	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.3	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.6	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.4	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.2	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.4	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.4	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.7	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.3	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	1.2	GO:0005518	collagen binding(GO:0005518)
0.0	0.3	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.0	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.2	GO:0060229	lipase activator activity(GO:0060229)
0.0	0.2	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.3	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.2	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.3	GO:0070888	E-box binding(GO:0070888)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	1.6	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.3	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	1.1	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.2	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.4	GO:0019003	GDP binding(GO:0019003)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.2	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	1.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.0	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.0	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.3	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.0	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.5	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.3	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.6	GO:0005507	copper ion binding(GO:0005507)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	2.3	GO:0008237	metallopeptidase activity(GO:0008237)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.0	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0043176	amine binding(GO:0043176)
0.0	0.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	2.0	GO:0003924	GTPase activity(GO:0003924)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0016411	acylglycerol O-acyltransferase activity(GO:0016411)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	1.0	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	1.5	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	3.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	4.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.3	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.6	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.1	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.5	PID MTOR 4PATHWAY	mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.9	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.5	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.1	REACTOME SIGNALLING BY NGF	Genes involved in Signalling by NGF
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.0	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.0	0.0	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	1.0	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME PI3K EVENTS IN ERBB2 SIGNALING	Genes involved in PI3K events in ERBB2 signaling
0.0	0.2	REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	Genes involved in Negative regulation of FGFR signaling
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.3	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.0	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport