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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for PRDM1

Z-value: 4.18

Motif logo

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Transcription factors associated with PRDM1

Gene Symbol Gene ID Gene Info
PRDM1
ENSG00000057657.10 PR/SET domain 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_106474855_106475295PRDM1591200.1339710.491.8e-01Click!
chr6_106531584_106531735PRDM125360.3378200.442.4e-01Click!
chr6_106533592_106533944PRDM14270.8722790.412.7e-01Click!
chr6_106445374_106445525PRDM1887460.0842010.402.8e-01Click!
chr6_106542111_106542262PRDM142950.2591460.393.0e-01Click!

Activity of the PRDM1 motif across conditions

Conditions sorted by the z-value of the PRDM1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_15390844_15391029 2.55 FAM171A1
 family with sequence similarity 171, member A1
 22122
 0.25
chr10_52984247_52984441 1.96 RP11-40C11.2
21222
 0.19
chr17_78044749_78045392 1.83 CCDC40
 coiled-coil domain containing 40
 12346
 0.15
chr18_40710046_40710304 1.62 RIT2
 Ras-like without CAAX 2
 14518
 0.31
chr16_65566073_65566543 1.59 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 410040
 0.01
chr2_40506166_40506540 1.53 AC007377.1
18206
 0.24
chr6_151392247_151392482 1.43 RP1-292B18.3
15171
 0.18
chr10_61927237_61927410 1.34 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
 669
 0.8
chr4_99468302_99468540 1.34 RP11-724M22.1
50906
 0.16
chr8_58660875_58661197 1.33 ENSG00000252057
 .
 191892
 0.03
chr13_21289085_21289250 1.33 ENSG00000265710
 .
 11325
 0.19
chr6_131290698_131290904 1.31 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 822
 0.76
chr5_144624790_144624969 1.31 ENSG00000221467
 .
 47541
 0.21
chr2_151343410_151343893 1.28 RND3
 Rho family GTPase 3
 530
 0.88
chr1_163039657_163039882 1.25 RGS4
 regulator of G-protein signaling 4
 618
 0.82
chr11_104788188_104788675 1.25 RP11-693N9.2
7789
 0.2
chrX_83618810_83618981 1.23 ENSG00000221494
 .
 138059
 0.05
chr4_160170135_160170337 1.23 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
 17797
 0.23
chr15_62916920_62917378 1.21 RP11-625H11.1
 Uncharacterized protein
 20231
 0.19
chr7_92325122_92325607 1.21 ENSG00000206763
 .
 5764
 0.28
chr11_2966476_2966712 1.21 PHLDA2
 pleckstrin homology-like domain, family A, member 2
 15909
 0.11
chr8_123256270_123256596 1.21 ENSG00000238901
 .
 427097
 0.01
chr6_6005898_6006049 1.21 NRN1
 neuritin 1
 1227
 0.56
chr13_41013314_41013519 1.21 ENSG00000252812
 .
 31839
 0.22
chr18_7460561_7460853 1.20 PTPRM
 protein tyrosine phosphatase, receptor type, M
 106073
 0.07
chr12_65997242_65997414 1.18 HMGA2
 high mobility group AT-hook 2
 220583
 0.02
chr1_174383473_174383626 1.18 GPR52
 G protein-coupled receptor 52
 33663
 0.21
chr8_134203052_134203203 1.17 WISP1
 WNT1 inducible signaling pathway protein 1
 155
 0.97
chr3_178787859_178788171 1.15 ZMAT3
 zinc finger, matrin-type 3
 1339
 0.48
chr13_34061717_34062025 1.15 STARD13
 StAR-related lipid transfer (START) domain containing 13
 137104
 0.05
chr12_120246787_120247132 1.14 CIT
 citron (rho-interacting, serine/threonine kinase 21)
 5772
 0.26
chr6_132735691_132735842 1.13 MOXD1
 monooxygenase, DBH-like 1
 13082
 0.25
chr3_187755166_187755324 1.13 LPP
 LIM domain containing preferred translocation partner in lipoma
 115827
 0.06
chr11_46307450_46307608 1.13 CREB3L1
 cAMP responsive element binding protein 3-like 1
 8301
 0.18
chr4_126541169_126541320 1.12 FAT4
 FAT atypical cadherin 4
 226153
 0.02
chr11_88914566_88914721 1.10 TYR
 tyrosinase
 4023
 0.33
chr1_116920744_116920998 1.09 ATP1A1
 ATPase, Na+/K+ transporting, alpha 1 polypeptide
 4162
 0.19
chr1_47119420_47119571 1.09 ATPAF1
 ATP synthase mitochondrial F1 complex assembly factor 1
 4904
 0.15
chr2_161808984_161809250 1.07 ENSG00000244372
 .
 75059
 0.12
chr1_201914577_201914874 1.06 LMOD1
 leiomodin 1 (smooth muscle)
 990
 0.39
chr17_17863110_17863392 1.06 TOM1L2
 target of myb1-like 2 (chicken)
 12460
 0.15
chr2_191511664_191511958 1.02 NAB1
 NGFI-A binding protein 1 (EGR1 binding protein 1)
 339
 0.9
chr3_186822986_186823144 1.02 RPL39L
 ribosomal protein L39-like
 34207
 0.17
chr1_180881031_180881376 1.01 KIAA1614
 KIAA1614
 1122
 0.51
chr11_122072907_122073271 1.01 ENSG00000207994
 .
 50073
 0.12
chr9_2126015_2126202 1.01 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 31572
 0.18
chr10_30209872_30210248 1.00 KIAA1462
 KIAA1462
 138393
 0.05
chr10_117740714_117740886 1.00 GFRA1
 GDNF family receptor alpha 1
 274507
 0.02
chr2_134484497_134484648 1.00 ENSG00000200708
 .
 130910
 0.05
chr1_219445701_219445873 0.99 RP11-135J2.4
98484
 0.08
chr10_116157125_116157362 0.99 AFAP1L2
 actin filament associated protein 1-like 2
 6996
 0.24
chr4_181928076_181928259 0.99 ENSG00000251742
 .
 828094
 0.0
chr4_87503159_87503484 0.98 MAPK10
 mitogen-activated protein kinase 10
 11942
 0.21
chr5_57368325_57368559 0.98 ENSG00000238899
 .
 2427
 0.45
chr11_63713225_63713426 0.98 NAA40
 N(alpha)-acetyltransferase 40, NatD catalytic subunit
 6605
 0.12
chr1_23894994_23895239 0.97 ID3
 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
 8831
 0.18
chr1_216692804_216692955 0.97 USH2A
 Usher syndrome 2A (autosomal recessive, mild)
 96141
 0.09
chr14_22848856_22849106 0.97 ENSG00000251002
 .
 52738
 0.09
chr1_71831543_71831741 0.97 ENSG00000229956
 .
 35763
 0.23
chr5_158524974_158525234 0.96 EBF1
 early B-cell factor 1
 1597
 0.48
chr15_83870418_83870820 0.96 HDGFRP3
 Hepatoma-derived growth factor-related protein 3
 6151
 0.19
chr14_55194961_55195128 0.96 SAMD4A
 sterile alpha motif domain containing 4A
 26507
 0.23
chr10_4093321_4093737 0.95 KLF6
 Kruppel-like factor 6
 266056
 0.02
chr6_161860014_161860217 0.95 AGPAT4
 1-acylglycerol-3-phosphate O-acyltransferase 4
 165022
 0.04
chr9_113282590_113282762 0.95 ENSG00000212254
 .
 19402
 0.24
chr12_91533014_91533165 0.95 DCN
 decorin
 6896
 0.25
chr10_121209276_121209427 0.94 GRK5
 G protein-coupled receptor kinase 5
 71402
 0.09
chr5_87798376_87798680 0.94 TMEM161B-AS1
 TMEM161B antisense RNA 1
 76016
 0.11
chr7_116332995_116333296 0.93 MET
 met proto-oncogene
 5994
 0.27
chr12_76376819_76377254 0.93 ENSG00000243420
 .
 25126
 0.18
chr1_243517492_243517644 0.93 ENSG00000265201
 .
 8090
 0.26
chr9_75708779_75709072 0.92 ALDH1A1
 aldehyde dehydrogenase 1 family, member A1
 13567
 0.27
chr5_14449868_14450019 0.92 TRIO
 trio Rho guanine nucleotide exchange factor
 38614
 0.21
chr8_92988247_92988452 0.92 GS1-5L10.1
213
 0.96
chr10_90966269_90966420 0.91 CH25H
 cholesterol 25-hydroxylase
 727
 0.67
chr9_112542645_112542955 0.91 AKAP2
 A kinase (PRKA) anchor protein 2
 31
 0.37
chr8_77585853_77586055 0.89 ZFHX4
 zinc finger homeobox 4
 7500
 0.24
chr8_16645234_16645451 0.89 ENSG00000264092
 .
 75663
 0.12
chr7_25835612_25835941 0.89 ENSG00000199085
 .
 153830
 0.04
chr9_18490908_18491217 0.89 ADAMTSL1
 ADAMTS-like 1
 16831
 0.27
chr2_143773567_143773818 0.88 ENSG00000221169
 .
 10332
 0.28
chr5_165798296_165798496 0.88 ENSG00000264903
 .
 211871
 0.03
chr19_55598672_55599034 0.88 EPS8L1
 EPS8-like 1
 7093
 0.1
chr10_124222195_124222452 0.88 HTRA1
 HtrA serine peptidase 1
 1282
 0.44
chr15_49760511_49761130 0.88 FGF7
 fibroblast growth factor 7
 45363
 0.16
chr6_134212007_134212270 0.88 RP3-323P13.2
936
 0.53
chr8_122274743_122274894 0.88 ENSG00000221644
 .
 75686
 0.12
chrY_21763188_21763339 0.87 TXLNG2P
 taxilin gamma 2, pseudogene
 4821
 0.27
chr11_14467853_14468182 0.86 ENSG00000251991
 .
 32421
 0.18
chr18_50434264_50434415 0.86 DCC
 deleted in colorectal carcinoma
 26803
 0.22
chr18_53526273_53526597 0.85 TCF4
 transcription factor 4
 194417
 0.03
chr5_78858830_78859073 0.84 ENSG00000207391
 .
 28275
 0.18
chr3_152313885_152314285 0.84 RP11-362A9.3
99483
 0.08
chr2_12129216_12129367 0.84 ENSG00000238503
 .
 41207
 0.19
chr6_49294723_49295128 0.84 ENSG00000252457
 .
 17596
 0.27
chr3_145616284_145616545 0.84 RP11-274H2.5
163052
 0.04
chr18_53775687_53775874 0.84 ENSG00000201816
 .
 28955
 0.27
chr8_50826499_50826650 0.84 SNTG1
 syntrophin, gamma 1
 1869
 0.53
chr2_98630005_98630391 0.84 TMEM131
 transmembrane protein 131
 17810
 0.24
chr18_67834074_67834322 0.84 RTTN
 rotatin
 38764
 0.21
chr11_131487348_131487499 0.83 NTM
 neurotrimin
 35518
 0.18
chr22_28174315_28174484 0.83 MN1
 meningioma (disrupted in balanced translocation) 1
 23087
 0.23
chr20_49465299_49465721 0.83 ENSG00000265062
 .
 11935
 0.18
chr1_78961568_78961719 0.83 PTGFR
 prostaglandin F receptor (FP)
 4886
 0.31
chr13_32119960_32120148 0.83 RXFP2
 relaxin/insulin-like family peptide receptor 2
 193620
 0.03
chr9_122707486_122707725 0.82 ENSG00000207814
 .
 299723
 0.01
chr11_111445251_111445475 0.82 SIK2
 salt-inducible kinase 2
 27752
 0.11
chr10_131761561_131761767 0.81 EBF3
 early B-cell factor 3
 441
 0.9
chr5_120534956_120535178 0.81 ENSG00000222609
 .
 488532
 0.01
chr2_199480864_199481015 0.81 ENSG00000252511
 .
 49486
 0.2
chr18_53167832_53168083 0.81 RP11-619L19.2
8551
 0.19
chr3_121151020_121151375 0.80 POLQ
 polymerase (DNA directed), theta
 113656
 0.06
chr10_34630198_34630349 0.80 PARD3
 par-3 family cell polarity regulator
 31188
 0.25
chrX_99900030_99900181 0.79 SRPX2
 sushi-repeat containing protein, X-linked 2
 890
 0.57
chr6_47165564_47165740 0.79 TNFRSF21
 tumor necrosis factor receptor superfamily, member 21
 111989
 0.07
chr6_88506291_88506649 0.79 ENSG00000207131
 .
 29533
 0.16
chr17_13486518_13486693 0.79 HS3ST3A1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
 18639
 0.23
chr7_16473361_16473576 0.78 ISPD
 isoprenoid synthase domain containing
 12521
 0.23
chrX_83420601_83420752 0.78 RPS6KA6
 ribosomal protein S6 kinase, 90kDa, polypeptide 6
 22239
 0.25
chr8_11349538_11349737 0.78 BLK
 B lymphoid tyrosine kinase
 1873
 0.29
chr2_205920685_205921182 0.78 PARD3B
 par-3 family cell polarity regulator beta
 510210
 0.0
chr14_65273817_65273968 0.77 SPTB
 spectrin, beta, erythrocytic
 15920
 0.19
chr4_87373379_87373575 0.77 MAPK10
 mitogen-activated protein kinase 10
 806
 0.74
chr2_16831792_16832248 0.77 FAM49A
 family with sequence similarity 49, member A
 15076
 0.3
chr6_11231077_11231290 0.77 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 1708
 0.44
chr7_132765840_132766055 0.76 CHCHD3
 coiled-coil-helix-coiled-coil-helix domain containing 3
 853
 0.59
chr4_159574164_159574322 0.76 C4orf46
 chromosome 4 open reading frame 46
 18801
 0.16
chr4_86745352_86745503 0.76 ARHGAP24
 Rho GTPase activating protein 24
 3471
 0.34
chr5_80690086_80690663 0.76 ACOT12
 acyl-CoA thioesterase 12
 376
 0.91
chr14_55796796_55797030 0.76 RP11-665C16.5
9306
 0.24
chr2_145753160_145753596 0.76 ENSG00000253036
 .
 339260
 0.01
chr5_102203960_102204196 0.76 PAM
 peptidylglycine alpha-amidating monooxygenase
 2258
 0.46
chr6_12279974_12280135 0.75 EDN1
 endothelin 1
 10542
 0.3
chr4_124776288_124776439 0.75 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 455240
 0.01
chr8_95273934_95274493 0.75 GEM
 GTP binding protein overexpressed in skeletal muscle
 360
 0.91
chr18_30310087_30311054 0.75 AC012123.1
 Uncharacterized protein
 39188
 0.17
chr20_44699432_44699601 0.75 NCOA5
 nuclear receptor coactivator 5
 19075
 0.14
chr1_214491340_214491539 0.75 SMYD2
 SET and MYND domain containing 2
 12881
 0.25
chr4_138463714_138463954 0.75 PCDH18
 protocadherin 18
 10186
 0.33
chr17_11852046_11852277 0.75 RP11-1096G20.5
28750
 0.16
chr10_4425832_4426362 0.74 ENSG00000207124
 .
 131047
 0.06
chr6_21916023_21916204 0.74 ENSG00000222515
 .
 169660
 0.04
chr8_119115834_119115985 0.74 EXT1
 exostosin glycosyltransferase 1
 6744
 0.34
chr10_51811950_51812150 0.74 RP11-324H6.5
11086
 0.19
chr6_99212409_99212624 0.73 POU3F2
 POU class 3 homeobox 2
 70064
 0.14
chr2_199639717_199640158 0.73 ENSG00000252511
 .
 208484
 0.03
chr3_99679363_99679603 0.73 ENSG00000264897
 .
 3759
 0.33
chr21_18376217_18376955 0.72 ENSG00000239023
 .
 285269
 0.01
chr11_43598101_43598272 0.72 ENSG00000199077
 .
 4758
 0.24
chr13_31271674_31272060 0.72 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
 37778
 0.19
chr11_32383224_32383375 0.72 WT1
 Wilms tumor 1
 38862
 0.19
chr1_208260069_208260332 0.72 PLXNA2
 plexin A2
 157465
 0.04
chr2_52632101_52632252 0.72 ENSG00000202195
 .
 107043
 0.08
chr15_44485809_44485960 0.71 FRMD5
 FERM domain containing 5
 760
 0.75
chr4_140737330_140737550 0.71 ENSG00000252233
 .
 21853
 0.23
chr11_85429919_85430085 0.71 SYTL2
 synaptotagmin-like 2
 123
 0.96
chr8_97505496_97505647 0.71 SDC2
 syndecan 2
 8
 0.99
chr13_102965778_102965929 0.71 FGF14-AS1
 FGF14 antisense RNA 1
 54036
 0.15
chr18_42366702_42366923 0.70 SETBP1
 SET binding protein 1
 89683
 0.1
chr12_68246942_68247109 0.70 IFNG-AS1
 IFNG antisense RNA 1
 136200
 0.05
chr7_84198152_84198303 0.70 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
 76187
 0.12
chr14_54605059_54605210 0.70 BMP4
 bone morphogenetic protein 4
 179655
 0.03
chr5_54834427_54834797 0.69 PPAP2A
 phosphatidic acid phosphatase type 2A
 3734
 0.27
chr5_111952744_111952991 0.69 APC
 adenomatous polyposis coli
 90328
 0.09
chr1_161932087_161932899 0.69 OLFML2B
 olfactomedin-like 2B
 22529
 0.22
chr11_96438289_96438578 0.69 ENSG00000200411
 .
 230577
 0.02
chr22_40672320_40672471 0.69 TNRC6B
 trinucleotide repeat containing 6B
 11388
 0.23
chr7_19155354_19155672 0.68 TWIST1
 twist family bHLH transcription factor 1
 1782
 0.28
chr1_59522619_59522770 0.68 FGGY
 FGGY carbohydrate kinase domain containing
 239616
 0.02
chr12_76426636_76426787 0.68 PHLDA1
 pleckstrin homology-like domain, family A, member 1
 1001
 0.51
chr9_118917834_118918063 0.68 PAPPA
 pregnancy-associated plasma protein A, pappalysin 1
 1865
 0.44
chr6_170768539_170768975 0.68 RP1-140C12.2
45530
 0.15
chr2_128491483_128491650 0.68 SFT2D3
 SFT2 domain containing 3
 32969
 0.13
chr11_88390713_88390864 0.68 ENSG00000207113
 .
 44709
 0.2
chr17_77042563_77042714 0.67 C1QTNF1
 C1q and tumor necrosis factor related protein 1
 2963
 0.2
chr2_136598368_136598551 0.67 LCT
 lactase
 3709
 0.2
chr2_67801375_67801526 0.67 ETAA1
 Ewing tumor-associated antigen 1
 176999
 0.03
chr12_17794706_17795007 0.67 ENSG00000206662
 .
 69012
 0.15
chr10_53627774_53628104 0.67 CSTF2T
 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
 168584
 0.04
chr1_70916763_70916914 0.67 CTH
 cystathionase (cystathionine gamma-lyase)
 39772
 0.17
chr4_184797459_184798247 0.67 STOX2
 storkhead box 2
 28656
 0.22
chr3_120003475_120003938 0.67 GPR156
 G protein-coupled receptor 156
 235
 0.94
chr15_74657875_74658107 0.66 CTD-2311M21.3
215
 0.75
chr5_140430825_140431264 0.66 PCDHB1
 protocadherin beta 1
 65
 0.96
chr4_19264306_19264465 0.66 ENSG00000251816
 .
 80906
 0.12
chr17_56310096_56310247 0.66 LPO
 lactoperoxidase
 5616
 0.14
chr9_110400851_110401256 0.66 ENSG00000202308
 .
 24474
 0.24
chr5_89167593_89167744 0.66 ENSG00000264342
 .
 144869
 0.05
chr6_134494547_134494698 0.65 SGK1
 serum/glucocorticoid regulated kinase 1
 1380
 0.45
chr4_89730559_89730710 0.65 FAM13A
 family with sequence similarity 13, member A
 13718
 0.24
chr18_72509515_72509666 0.65 ZNF407
 zinc finger protein 407
 166614
 0.04
chr5_60599280_60599578 0.65 ZSWIM6
 zinc finger, SWIM-type containing 6
 28671
 0.23
chr1_198092217_198092386 0.65 NEK7
 NIMA-related kinase 7
 33792
 0.24
chr6_128799339_128799870 0.65 RP1-86D1.5
22068
 0.14
chr18_19481957_19482108 0.65 ENSG00000252325
 .
 22270
 0.15
chr3_105656990_105657196 0.64 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 68697
 0.15
chr20_58004477_58004645 0.64 ENSG00000263903
 .
 83026
 0.09
chr9_80985944_80986319 0.64 PSAT1
 phosphoserine aminotransferase 1
 74072
 0.12
chr7_84292969_84293132 0.64 ENSG00000265050
 .
 2274
 0.47
chr7_105134630_105134781 0.64 PUS7
 pseudouridylate synthase 7 homolog (S. cerevisiae)
 13877
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.2 0.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 0.5 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.3 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.3 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.3 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.3 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 0.4 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.3 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.3 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.2 GO:0060435 bronchiole development(GO:0060435)
0.1 0.2 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.4 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.4 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1 0.3 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 0.8 GO:0031000 response to caffeine(GO:0031000)
0.1 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.6 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.2 GO:0090195 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.1 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.9 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 0.2 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.4 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.2 GO:0008354 germ cell migration(GO:0008354)
0.1 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.3 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.1 0.2 GO:0032351 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.3 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.3 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.2 GO:0014824 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1 0.3 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 0.2 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0052167 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.6 GO:0043616 keratinocyte proliferation(GO:0043616)
0.0 0.4 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.6 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.3 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:1901889 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:1903670 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.6 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.2 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.2 GO:0031529 ruffle organization(GO:0031529)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.2 GO:0016556 mRNA modification(GO:0016556)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.2 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.2 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.3 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 0.0 GO:0060526 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.0 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0051883 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.0 GO:0048278 vesicle docking(GO:0048278)
0.0 0.0 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0006385 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198) axon midline choice point recognition(GO:0016199)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 1.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.2 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 2.4 GO:0006184 obsolete GTP catabolic process(GO:0006184)
0.0 0.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.0 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.5 GO:0042552 myelination(GO:0042552)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.0 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.0 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.0 GO:0033079 immature T cell proliferation(GO:0033079)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:0055057 neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0010873 positive regulation of cholesterol esterification(GO:0010873)
0.0 0.0 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.5 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.0 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.0 0.0 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure(GO:0003071)
0.0 0.0 GO:0048867 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.2 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.1 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.2 GO:1900076 regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.0 0.0 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0008038 neuron recognition(GO:0008038)
0.0 0.2 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.0 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 0.0 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 0.0 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.2 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0008091 spectrin(GO:0008091)
0.1 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.2 GO:0043218 compact myelin(GO:0043218)
0.1 0.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0044304 main axon(GO:0044304)
0.0 1.5 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 5.0 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.0 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 1.1 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.2 GO:0016234 inclusion body(GO:0016234)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3 0.8 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 0.9 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 0.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 0.8 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.0 GO:0030507 spectrin binding(GO:0030507)
0.1 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.3 GO:0005113 patched binding(GO:0005113)
0.1 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.6 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1 0.2 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.4 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.7 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.0 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.0 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 2.3 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.0 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.0 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0043176 amine binding(GO:0043176)
0.0 0.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 2.0 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 4.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.0 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.0 0.2 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.0 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport