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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PRDM14

Z-value: 0.90

Motif logo

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Transcription factors associated with PRDM14

Gene Symbol Gene ID Gene Info
PRDM14
ENSG00000147596.3 PRDM14

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
PRDM14chr8_70984934_7098508510810.541383-0.608.5e-02Click!
PRDM14chr8_70984555_709847067020.707363-0.551.2e-01Click!
PRDM14chr8_70982226_7098237712610.4903650.462.1e-01Click!
PRDM14chr8_70947239_70947390362480.1555870.137.4e-01Click!
PRDM14chr8_70984004_709842752110.9445060.039.5e-01Click!

Activity of the PRDM14 motif across conditions

Conditions sorted by the z-value of the PRDM14 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr22_40297430_40297673 1.09 GRAP2
 GRB2-related adaptor protein 2
 438
 0.81
chr4_109085952_109086103 0.80 LEF1
 lymphoid enhancer-binding factor 1
 1430
 0.44
chr6_501893_502410 0.74 RP1-20B11.2
22020
 0.26
chr5_133455627_133455909 0.71 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 3541
 0.27
chr10_11208288_11208755 0.69 CELF2
 CUGBP, Elav-like family member 2
 1030
 0.57
chr1_118149801_118150025 0.64 FAM46C
 family with sequence similarity 46, member C
 1357
 0.38
chr14_22993528_22993679 0.60 TRAJ15
 T cell receptor alpha joining 15
 4977
 0.12
chr15_86126717_86127003 0.58 RP11-815J21.2
3451
 0.22
chr8_134509191_134509342 0.57 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 2338
 0.44
chr5_133454026_133454256 0.57 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 2825
 0.3
chr17_78845601_78845793 0.56 RPTOR
 regulatory associated protein of MTOR, complex 1
 50827
 0.1
chr17_38716835_38717173 0.53 CCR7
 chemokine (C-C motif) receptor 7
 261
 0.91
chr20_56202934_56203085 0.53 ZBP1
 Z-DNA binding protein 1
 7377
 0.24
chr10_82228022_82228360 0.51 TSPAN14
 tetraspanin 14
 9133
 0.21
chr15_75080868_75081404 0.50 ENSG00000264386
 .
 38
 0.76
chr2_27072177_27072340 0.49 DPYSL5
 dihydropyrimidinase-like 5
 882
 0.61
chr1_160737807_160738093 0.48 LY9
 lymphocyte antigen 9
 27914
 0.13
chr17_80274181_80274428 0.48 CD7
 CD7 molecule
 1124
 0.35
chr19_1029334_1029485 0.47 CNN2
 calponin 2
 1727
 0.16
chr12_51318719_51318989 0.47 METTL7A
 methyltransferase like 7A
 320
 0.86
chr6_2222017_2222664 0.46 GMDS
 GDP-mannose 4,6-dehydratase
 23586
 0.28
chr9_6414096_6414470 0.45 UHRF2
 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
 865
 0.64
chr6_24910150_24910301 0.45 FAM65B
 family with sequence similarity 65, member B
 970
 0.62
chr20_822528_822694 0.42 FAM110A
 family with sequence similarity 110, member A
 2674
 0.33
chr8_30776682_30776833 0.42 TEX15
 testis expressed 15
 70149
 0.11
chr9_96341921_96342072 0.40 PHF2
 PHD finger protein 2
 3087
 0.26
chr11_46353937_46354088 0.40 DGKZ
 diacylglycerol kinase, zeta
 443
 0.79
chr3_46995163_46995374 0.39 CCDC12
 coiled-coil domain containing 12
 23002
 0.14
chr6_32605503_32605654 0.39 HLA-DQA1
 major histocompatibility complex, class II, DQ alpha 1
 381
 0.81
chr2_182322868_182323440 0.38 ITGA4
 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
 999
 0.69
chr4_109062684_109062835 0.38 LEF1
 lymphoid enhancer-binding factor 1
 24698
 0.2
chr6_159465648_159465970 0.38 TAGAP
 T-cell activation RhoGTPase activating protein
 241
 0.93
chr1_175157943_175158108 0.37 KIAA0040
 KIAA0040
 3865
 0.32
chr1_47133001_47133167 0.37 ATPAF1
 ATP synthase mitochondrial F1 complex assembly factor 1
 1015
 0.38
chr4_103266826_103266980 0.37 SLC39A8
 solute carrier family 39 (zinc transporter), member 8
 272
 0.92
chr10_104195058_104195350 0.36 ENSG00000202569
 .
 1065
 0.31
chr14_95785313_95785520 0.36 CLMN
 calmin (calponin-like, transmembrane)
 827
 0.72
chr18_45526509_45526660 0.36 ZBTB7C
 zinc finger and BTB domain containing 7C
 40910
 0.18
chr10_104571858_104572081 0.35 ENSG00000252994
 .
 8283
 0.13
chr14_69865476_69865674 0.34 SLC39A9
 solute carrier family 39, member 9
 166
 0.59
chrX_51636214_51636365 0.34 MAGED1
 melanoma antigen family D, 1
 340
 0.91
chr15_65592203_65592532 0.34 ENSG00000199568
 .
 3978
 0.15
chr15_31652269_31652420 0.34 KLF13
 Kruppel-like factor 13
 6013
 0.32
chr13_74339708_74339938 0.33 KLF12
 Kruppel-like factor 12
 229363
 0.02
chr13_97874593_97875664 0.33 MBNL2
 muscleblind-like splicing regulator 2
 519
 0.87
chr11_62571959_62572195 0.32 NXF1
 nuclear RNA export factor 1
 420
 0.56
chr16_53986265_53986480 0.32 FTO
 fat mass and obesity associated
 18430
 0.19
chr1_32718292_32718517 0.32 LCK
 lymphocyte-specific protein tyrosine kinase
 1529
 0.2
chr16_18033135_18033286 0.31 NPIPA8
 nuclear pore complex interacting protein family, member A8
 384882
 0.01
chr12_48499913_48500348 0.31 SENP1
 SUMO1/sentrin specific peptidase 1
 39
 0.49
chr8_82024010_82024221 0.30 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 188
 0.97
chr20_54998016_54998238 0.30 CASS4
 Cas scaffolding protein family member 4
 10810
 0.13
chr9_133643618_133643769 0.30 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 54326
 0.12
chr13_49721188_49721557 0.30 FNDC3A
 fibronectin type III domain containing 3A
 36923
 0.16
chr18_43267753_43268033 0.29 SLC14A2
 solute carrier family 14 (urea transporter), member 2
 21786
 0.17
chr14_52739518_52739669 0.29 PTGDR
 prostaglandin D2 receptor (DP)
 5063
 0.28
chr22_17567534_17567787 0.29 IL17RA
 interleukin 17 receptor A
 1811
 0.31
chr6_143250907_143251058 0.29 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 15356
 0.25
chr22_27070409_27070560 0.28 CRYBA4
 crystallin, beta A4
 52556
 0.12
chr11_85773706_85774153 0.28 PICALM
 phosphatidylinositol binding clathrin assembly protein
 5893
 0.24
chr12_49760663_49760953 0.28 SPATS2
 spermatogenesis associated, serine-rich 2
 63
 0.96
chr19_39728332_39728587 0.28 IFNL3
 interferon, lambda 3
 7187
 0.12
chr16_67517309_67517460 0.28 AGRP
 agouti related protein homolog (mouse)
 332
 0.75
chrY_1604612_1604993 0.27 NA
 NA
 > 106
 NA
chr6_20206769_20207068 0.27 RP11-239H6.2
5400
 0.25
chr7_92875407_92875558 0.27 CCDC132
 coiled-coil domain containing 132
 13444
 0.22
chr17_73073685_73074098 0.27 SLC16A5
 solute carrier family 16 (monocarboxylate transporter), member 5
 9931
 0.08
chr19_3986525_3986905 0.27 EEF2
 eukaryotic translation elongation factor 2
 1248
 0.29
chr9_132098681_132099276 0.27 ENSG00000242281
 .
 33762
 0.17
chr5_98369155_98369504 0.27 ENSG00000200351
 .
 96878
 0.08
chr2_113033235_113033667 0.27 ZC3H6
 zinc finger CCCH-type containing 6
 273
 0.91
chrX_1654663_1654996 0.27 P2RY8
 purinergic receptor P2Y, G-protein coupled, 8
 1171
 0.53
chr8_22398297_22398465 0.27 RP11-582J16.4
4537
 0.13
chr7_50348888_50349341 0.27 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 796
 0.76
chr8_38758238_38758438 0.27 PLEKHA2
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
 415
 0.84
chr7_7297838_7297989 0.26 C1GALT1
 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
 23962
 0.22
chr7_141437790_141437995 0.26 WEE2-AS1
 WEE2 antisense RNA 1
 128
 0.63
chr12_120967079_120967294 0.26 COQ5
 coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
 201
 0.89
chr19_1028850_1029154 0.26 CNN2
 calponin 2
 2134
 0.13
chr15_101788492_101788643 0.26 CHSY1
 chondroitin sulfate synthase 1
 3570
 0.21
chr22_21771228_21771443 0.26 HIC2
 hypermethylated in cancer 2
 358
 0.79
chr16_56968887_56969454 0.26 HERPUD1
 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
 144
 0.93
chr10_100227763_100227980 0.25 HPS1
 Hermansky-Pudlak syndrome 1
 21188
 0.19
chr7_55778225_55778376 0.25 FKBP9L
 FK506 binding protein 9-like
 2645
 0.29
chr1_36620951_36621452 0.25 MAP7D1
 MAP7 domain containing 1
 21
 0.97
chr7_50423750_50423901 0.25 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 56580
 0.14
chr9_123682878_123683088 0.25 TRAF1
 TNF receptor-associated factor 1
 6133
 0.22
chr7_44417747_44417898 0.25 CAMK2B
 calcium/calmodulin-dependent protein kinase II beta
 52567
 0.13
chr8_8747685_8748237 0.25 MFHAS1
 malignant fibrous histiocytoma amplified sequence 1
 3194
 0.25
chr1_36617295_36617817 0.25 TRAPPC3
 trafficking protein particle complex 3
 2458
 0.21
chr6_109802201_109802381 0.24 ZBTB24
 zinc finger and BTB domain containing 24
 2149
 0.19
chr2_113937983_113938134 0.24 AC016683.5
5121
 0.15
chr4_154418637_154418870 0.24 KIAA0922
 KIAA0922
 31252
 0.2
chr22_24109322_24109633 0.24 CHCHD10
 coiled-coil-helix-coiled-coil-helix domain containing 10
 586
 0.54
chr10_104956862_104957013 0.24 NT5C2
 5'-nucleotidase, cytosolic II
 3881
 0.25
chr12_92518025_92518176 0.24 C12orf79
 chromosome 12 open reading frame 79
 12697
 0.18
chr15_86037970_86038121 0.24 AKAP13
 A kinase (PRKA) anchor protein 13
 49226
 0.13
chr5_148727679_148728000 0.24 GRPEL2
 GrpE-like 2, mitochondrial (E. coli)
 2774
 0.17
chr7_127227981_127228310 0.23 ARF5
 ADP-ribosylation factor 5
 254
 0.89
chr10_99411142_99411293 0.23 PI4K2A
 phosphatidylinositol 4-kinase type 2 alpha
 10774
 0.13
chr2_74426850_74427050 0.23 MTHFD2
 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
 1207
 0.37
chr11_82461800_82462168 0.23 FAM181B
 family with sequence similarity 181, member B
 17078
 0.25
chr20_52204433_52204907 0.23 ZNF217
 zinc finger protein 217
 5034
 0.21
chrX_9801459_9801610 0.23 ENSG00000206844
 .
 41207
 0.15
chr1_155944536_155944687 0.23 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
 2500
 0.14
chr10_71905035_71905382 0.23 TYSND1
 trypsin domain containing 1
 1134
 0.47
chr15_91137292_91137443 0.23 CRTC3
 CREB regulated transcription coactivator 3
 422
 0.79
chr1_9715239_9715390 0.22 C1orf200
 chromosome 1 open reading frame 200
 670
 0.66
chr6_16135670_16135821 0.22 ENSG00000263712
 .
 6042
 0.19
chr12_114404344_114404564 0.22 RBM19
 RNA binding motif protein 19
 278
 0.94
chr11_62493191_62493431 0.22 HNRNPUL2
 heterogeneous nuclear ribonucleoprotein U-like 2
 1510
 0.15
chr9_132600041_132600192 0.22 USP20
 ubiquitin specific peptidase 20
 2359
 0.21
chr7_72721296_72721447 0.22 NSUN5
 NOP2/Sun domain family, member 5
 1430
 0.32
chr5_156569538_156569746 0.22 MED7
 mediator complex subunit 7
 144
 0.5
chr6_24949661_24949812 0.22 FAM65B
 family with sequence similarity 65, member B
 13548
 0.22
chr16_28890546_28890697 0.22 ATP2A1
 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
 57
 0.87
chr19_46018300_46018451 0.22 VASP
 vasodilator-stimulated phosphoprotein
 7626
 0.11
chr1_35659030_35659365 0.22 SFPQ
 splicing factor proline/glutamine-rich
 448
 0.79
chr20_39905047_39905444 0.22 ZHX3
 zinc fingers and homeoboxes 3
 4347
 0.24
chr11_65656225_65656433 0.22 FIBP
 fibroblast growth factor (acidic) intracellular binding protein
 319
 0.71
chr14_74416462_74416772 0.22 COQ6
 coenzyme Q6 monooxygenase
 12
 0.73
chr13_21714248_21714458 0.22 ENSG00000252128
 .
 257
 0.52
chr18_5295757_5296173 0.22 ZBTB14
 zinc finger and BTB domain containing 14
 74
 0.98
chr6_44041425_44041691 0.22 RP5-1120P11.1
831
 0.6
chr22_37822877_37823150 0.21 RP1-63G5.5
467
 0.46
chr11_575030_575208 0.21 PHRF1
 PHD and ring finger domains 1
 1367
 0.21
chrX_75371736_75371887 0.21 PBDC1
 polysaccharide biosynthesis domain containing 1
 20960
 0.27
chr6_152492731_152492882 0.21 SYNE1
 spectrin repeat containing, nuclear envelope 1
 3307
 0.38
chr2_11894079_11894417 0.21 LPIN1
 lipin 1
 7484
 0.14
chr3_46923397_46923551 0.21 MYL3
 myosin, light chain 3, alkali; ventricular, skeletal, slow
 185
 0.5
chrX_75362891_75363042 0.21 PBDC1
 polysaccharide biosynthesis domain containing 1
 29805
 0.25
chr6_20570918_20571069 0.21 CDKAL1
 CDK5 regulatory subunit associated protein 1-like 1
 24421
 0.21
chr1_185663326_185663550 0.21 HMCN1
 hemicentin 1
 40245
 0.17
chr22_21872004_21872399 0.21 PI4KAP2
 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
 379
 0.75
chr15_94774265_94774529 0.21 MCTP2
 multiple C2 domains, transmembrane 2
 370
 0.93
chr6_44899717_44900076 0.20 SUPT3H
 suppressor of Ty 3 homolog (S. cerevisiae)
 23351
 0.28
chr19_51873675_51874043 0.20 CLDND2
 claudin domain containing 2
 1602
 0.15
chr17_8026048_8026346 0.20 HES7
 hes family bHLH transcription factor 7
 1205
 0.26
chr8_42995208_42995412 0.20 HGSNAT
 heparan-alpha-glucosaminide N-acetyltransferase
 246
 0.93
chr9_123472752_123472978 0.20 MEGF9
 multiple EGF-like-domains 9
 3747
 0.3
chrY_1276930_1277081 0.20 NA
 NA
 > 106
 NA
chr18_60824857_60825062 0.20 RP11-299P2.1
6406
 0.25
chr10_126406911_126407062 0.20 FAM53B-AS1
 FAM53B antisense RNA 1
 14233
 0.17
chr2_226329681_226329881 0.20 NYAP2
 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
 56184
 0.18
chrX_1326928_1327079 0.20 CRLF2
 cytokine receptor-like factor 2
 4524
 0.21
chr8_23397961_23398112 0.20 SLC25A37
 solute carrier family 25 (mitochondrial iron transporter), member 37
 11463
 0.16
chr18_60823045_60823200 0.20 RP11-299P2.1
4569
 0.27
chrX_118369551_118369783 0.20 PGRMC1
 progesterone receptor membrane component 1
 549
 0.83
chr2_54786735_54787181 0.20 SPTBN1
 spectrin, beta, non-erythrocytic 1
 1427
 0.42
chr10_71929129_71929743 0.20 SAR1A
 SAR1 homolog A (S. cerevisiae)
 792
 0.63
chr17_75450125_75450790 0.20 SEPT9
 septin 9
 295
 0.88
chr1_155942988_155943139 0.20 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
 952
 0.36
chr11_85956297_85957260 0.20 EED
 embryonic ectoderm development
 502
 0.83
chr1_31234118_31234269 0.20 LAPTM5
 lysosomal protein transmembrane 5
 3526
 0.21
chr12_52346063_52346405 0.20 ACVR1B
 activin A receptor, type IB
 706
 0.62
chrX_129220262_129220541 0.20 ELF4
 E74-like factor 4 (ets domain transcription factor)
 23935
 0.18
chr8_67626578_67626729 0.20 SGK3
 serum/glucocorticoid regulated kinase family, member 3
 2000
 0.3
chr4_10459085_10459385 0.19 ZNF518B
 zinc finger protein 518B
 206
 0.96
chr18_13438227_13438398 0.19 LDLRAD4-AS1
 LDLRAD4 antisense RNA 1
 10833
 0.12
chr1_2163627_2164198 0.19 SKI
 v-ski avian sarcoma viral oncogene homolog
 3778
 0.16
chr6_43337603_43337930 0.19 ZNF318
 zinc finger protein 318
 585
 0.7
chr10_29096673_29096824 0.19 C10orf126
 chromosome 10 open reading frame 126
 38589
 0.16
chr17_66233779_66233987 0.19 AMZ2
 archaelysin family metallopeptidase 2
 9832
 0.16
chr9_104160646_104160869 0.19 MRPL50
 mitochondrial ribosomal protein L50
 129
 0.79
chr15_50644840_50645537 0.19 GABPB1
 GA binding protein transcription factor, beta subunit 1
 2133
 0.21
chr3_197353837_197354109 0.19 AC024560.3
746
 0.69
chr5_174905979_174906366 0.19 SFXN1
 sideroflexin 1
 577
 0.78
chr1_160548119_160548396 0.19 CD84
 CD84 molecule
 1006
 0.48
chr1_235805657_235805845 0.19 GNG4
 guanine nucleotide binding protein (G protein), gamma 4
 7542
 0.28
chr14_75800906_75801057 0.19 FOS
 FBJ murine osteosarcoma viral oncogene homolog
 54085
 0.1
chr2_97428078_97428820 0.19 CNNM4
 cyclin M4
 1810
 0.3
chr17_38490189_38490340 0.19 RARA
 retinoic acid receptor, alpha
 7376
 0.11
chr10_35775018_35775169 0.19 GJD4
 gap junction protein, delta 4, 40.1kDa
 119245
 0.05
chr10_73847731_73848399 0.19 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 21
 0.98
chr19_5624316_5624482 0.19 SAFB2
 scaffold attachment factor B2
 342
 0.77
chr17_57230990_57231141 0.19 SKA2
 spindle and kinetochore associated complex subunit 2
 1470
 0.21
chr17_74731558_74731709 0.19 MFSD11
 major facilitator superfamily domain containing 11
 314
 0.67
chr1_12139606_12139757 0.19 ENSG00000201135
 .
 1640
 0.3
chr14_39899307_39899586 0.18 FBXO33
 F-box protein 33
 1633
 0.47
chr10_102026913_102027138 0.18 CWF19L1
 CWF19-like 1, cell cycle control (S. pombe)
 412
 0.75
chr19_34663821_34664709 0.18 LSM14A
 LSM14A, SCD6 homolog A (S. cerevisiae)
 702
 0.77
chr12_57030254_57030540 0.18 BAZ2A
 bromodomain adjacent to zinc finger domain, 2A
 234
 0.88
chr13_47242269_47242651 0.18 LRCH1
 leucine-rich repeats and calponin homology (CH) domain containing 1
 11511
 0.28
chr20_52259090_52259799 0.18 ENSG00000238468
 .
 25853
 0.18
chrY_15017679_15018174 0.18 DDX3Y
 DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
 277
 0.95
chr13_99952403_99952624 0.18 GPR183
 G protein-coupled receptor 183
 7146
 0.21
chr7_90339651_90339847 0.18 CDK14
 cyclin-dependent kinase 14
 573
 0.85
chr1_32665798_32666702 0.18 CCDC28B
 coiled-coil domain containing 28B
 16
 0.94
chr1_209921149_209921488 0.18 TRAF3IP3
 TRAF3 interacting protein 3
 8059
 0.14
chr11_65342200_65342895 0.18 EHBP1L1
 EH domain binding protein 1-like 1
 962
 0.29
chr22_20428028_20428487 0.18 ENSG00000271796
 .
 5896
 0.13
chr1_21503574_21503811 0.18 EIF4G3
 eukaryotic translation initiation factor 4 gamma, 3
 315
 0.69
chr18_24867919_24868070 0.18 CHST9
 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
 102713
 0.09
chr1_165600518_165600732 0.18 MGST3
 microsomal glutathione S-transferase 3
 133
 0.96
chr11_133797734_133798200 0.18 IGSF9B
 immunoglobulin superfamily, member 9B
 18220
 0.18
chr11_62308687_62309106 0.18 RP11-864I4.3
4112
 0.1
chr2_29803342_29803493 0.18 ENSG00000266310
 .
 76558
 0.11
chr1_246280752_246281030 0.18 RP11-36N20.1
8963
 0.25
chr7_38389675_38390189 0.18 AMPH
 amphiphysin
 112781
 0.07
chr2_106362063_106362974 0.17 NCK2
 NCK adaptor protein 2
 330
 0.94

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PRDM14

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1 0.4 GO:0070670 response to interleukin-4(GO:0070670)
0.1 0.2 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.2 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.4 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.3 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.1 GO:0002335 mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.6 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.2 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 2.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.0 GO:0045588 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.1 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.0 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0051132 NK T cell activation(GO:0051132)
0.0 0.1 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0051000 positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.0 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.0 GO:0046471 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.0 GO:0002707 negative regulation of lymphocyte mediated immunity(GO:0002707)
0.0 0.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.0 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.0 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.0 GO:1903504 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.0 GO:0070431 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.1 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.0 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0071599 otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.0 0.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.0 0.1 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.0 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.0 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0070061 fructose binding(GO:0070061)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.0 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.0 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 SIG CHEMOTAXIS Genes related to chemotaxis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.0 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling