Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
Navigation
Downloads
Logo
CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PRDM4

Z-value: 0.80

Motif logo

logo of

Transcription factors associated with PRDM4

Gene Symbol Gene ID Gene Info
PRDM4
ENSG00000110851.7 PRDM4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
PRDM4chr12_108143303_10814347921610.269624-0.881.8e-03Click!
PRDM4chr12_108142710_10814287427600.230268-0.655.9e-02Click!
PRDM4chr12_108153036_10815320515850.344352-0.531.4e-01Click!
PRDM4chr12_108155132_1081556244410.8042660.363.4e-01Click!
PRDM4chr12_108153552_10815377710410.489436-0.324.0e-01Click!

Activity of the PRDM4 motif across conditions

Conditions sorted by the z-value of the PRDM4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_158274562_158274945 0.60 CYTIP
 cytohesin 1 interacting protein
 21173
 0.2
chr6_32159695_32160229 0.58 GPSM3
 G-protein signaling modulator 3
 683
 0.42
chr19_50003533_50003936 0.57 hsa-mir-150
 hsa-mir-150
 47
 0.8
chr1_9699551_9699702 0.56 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 12164
 0.16
chr15_33383427_33383578 0.56 FMN1
 formin 1
 23139
 0.25
chrX_153191913_153192277 0.54 ARHGAP4
 Rho GTPase activating protein 4
 116
 0.92
chr10_121276429_121276711 0.53 RGS10
 regulator of G-protein signaling 10
 10419
 0.24
chr14_22771842_22772128 0.51 ENSG00000251002
 .
 129734
 0.04
chr19_11640031_11640182 0.44 ECSIT
 ECSIT signalling integrator
 117
 0.92
chr6_15253008_15253181 0.44 JARID2
 jumonji, AT rich interactive domain 2
 3951
 0.23
chr7_38389357_38389573 0.44 AMPH
 amphiphysin
 113248
 0.07
chr7_147856085_147856236 0.41 CNTNAP2
 contactin associated protein-like 2
 25384
 0.26
chr14_105531964_105532391 0.41 GPR132
 G protein-coupled receptor 132
 395
 0.85
chr9_107591981_107592132 0.40 NIPSNAP3B
 nipsnap homolog 3B (C. elegans)
 65605
 0.11
chr1_111742376_111742661 0.39 DENND2D
 DENN/MADD domain containing 2D
 793
 0.38
chrX_9431281_9431551 0.39 TBL1X
 transducin (beta)-like 1X-linked
 45
 0.99
chr7_90893538_90893822 0.39 FZD1
 frizzled family receptor 1
 103
 0.99
chr3_170963778_170963929 0.38 TNIK
 TRAF2 and NCK interacting kinase
 20353
 0.26
chr5_1315569_1315720 0.38 ENSG00000263670
 .
 6152
 0.18
chr14_23010806_23011164 0.38 TRAJ15
 T cell receptor alpha joining 15
 12405
 0.1
chr2_231788728_231788879 0.37 GPR55
 G protein-coupled receptor 55
 1138
 0.46
chr1_198622996_198623151 0.37 RP11-553K8.5
13117
 0.23
chr1_159037657_159037949 0.36 ENSG00000265589
 .
 8764
 0.18
chr14_100537247_100537438 0.35 CTD-2376I20.1
3873
 0.18
chr10_88170804_88170968 0.34 GRID1
 glutamate receptor, ionotropic, delta 1
 44651
 0.14
chr15_101782791_101782964 0.34 CHSY1
 chondroitin sulfate synthase 1
 9260
 0.18
chrX_48776392_48776920 0.33 PIM2
 pim-2 oncogene
 355
 0.76
chr1_226066769_226066920 0.33 TMEM63A
 transmembrane protein 63A
 1465
 0.3
chr2_10169450_10169738 0.32 KLF11
 Kruppel-like factor 11
 13382
 0.13
chr22_31625511_31626031 0.31 ENSG00000202019
 .
 387
 0.76
chr6_41169596_41169747 0.31 TREML2
 triggering receptor expressed on myeloid cells-like 2
 739
 0.55
chr16_21519015_21519166 0.31 ENSG00000265462
 .
 1634
 0.33
chr22_50050359_50050996 0.31 C22orf34
 chromosome 22 open reading frame 34
 401
 0.87
chr10_112287695_112287846 0.30 DUSP5
 dual specificity phosphatase 5
 30174
 0.14
chr12_125477524_125477679 0.30 BRI3BP
 BRI3 binding protein
 645
 0.71
chr11_441689_441900 0.29 ANO9
 anoctamin 9
 217
 0.82
chr2_12862265_12862722 0.29 TRIB2
 tribbles pseudokinase 2
 4129
 0.3
chr5_17258045_17258196 0.29 ENSG00000252908
 .
 17400
 0.19
chr2_234296852_234297003 0.29 DGKD
 diacylglycerol kinase, delta 130kDa
 127
 0.96
chr9_99175747_99176261 0.29 ZNF367
 zinc finger protein 367
 4607
 0.23
chr3_16884765_16884916 0.29 PLCL2
 phospholipase C-like 2
 41612
 0.19
chr11_127910618_127910769 0.28 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 464596
 0.01
chr6_126067758_126068417 0.28 HEY2
 hes-related family bHLH transcription factor with YRPW motif 2
 723
 0.57
chr8_103136777_103137074 0.28 NCALD
 neurocalcin delta
 117
 0.91
chr17_80806215_80806449 0.28 ZNF750
 zinc finger protein 750
 7878
 0.16
chr1_147013251_147013702 0.27 BCL9
 B-cell CLL/lymphoma 9
 294
 0.94
chr2_146013147_146013298 0.27 ENSG00000253036
 .
 79416
 0.12
chr17_76254452_76254830 0.27 TMEM235
 transmembrane protein 235
 26519
 0.12
chrX_147583270_147583557 0.27 AFF2
 AF4/FMR2 family, member 2
 884
 0.51
chrX_30849195_30849346 0.26 TAB3-AS1
 TAB3 antisense RNA 1
 3470
 0.24
chr6_32408572_32408723 0.26 HLA-DRA
 major histocompatibility complex, class II, DR alpha
 992
 0.48
chr2_9613939_9614127 0.26 IAH1
 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
 86
 0.97
chr5_34916244_34916587 0.26 RAD1
 RAD1 homolog (S. pombe)
 456
 0.67
chr7_101784250_101784577 0.25 ENSG00000252824
 .
 53031
 0.12
chr1_172502667_172502917 0.25 SUCO
 SUN domain containing ossification factor
 435
 0.87
chr17_33640471_33640814 0.25 SLFN11
 schlafen family member 11
 39508
 0.12
chr6_42898071_42898286 0.25 CNPY3
 canopy FGF signaling regulator 3
 1196
 0.31
chr1_193153819_193153970 0.25 B3GALT2
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
 1890
 0.36
chr9_77762612_77762996 0.25 ENSG00000200041
 .
 33733
 0.15
chr4_107236640_107237312 0.25 AIMP1
 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
 123
 0.8
chr1_84902979_84903163 0.24 DNASE2B
 deoxyribonuclease II beta
 29158
 0.16
chr11_66887899_66888432 0.24 KDM2A
 lysine (K)-specific demethylase 2A
 1007
 0.52
chr2_26101893_26102047 0.24 ASXL2
 additional sex combs like 2 (Drosophila)
 585
 0.82
chr16_31548282_31548433 0.24 AHSP
 alpha hemoglobin stabilizing protein
 9059
 0.11
chr7_157306639_157306790 0.24 AC006372.6
726
 0.7
chr2_43438121_43438285 0.24 ZFP36L2
 ZFP36 ring finger protein-like 2
 15545
 0.22
chr14_103011281_103011526 0.24 ENSG00000266015
 .
 5422
 0.18
chr14_32030134_32030320 0.24 CTD-2213F21.3
313
 0.52
chr21_39844669_39844875 0.24 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
 25573
 0.26
chr12_58132957_58133143 0.23 AGAP2
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
 1021
 0.26
chr15_74286545_74286747 0.23 STOML1
 stomatin (EPB72)-like 1
 317
 0.52
chr9_134145569_134145886 0.23 FAM78A
 family with sequence similarity 78, member A
 153
 0.95
chr7_5729023_5729311 0.22 RNF216-IT1
 RNF216 intronic transcript 1 (non-protein coding)
 9075
 0.21
chr1_27114087_27114296 0.22 PIGV
 phosphatidylinositol glycan anchor biosynthesis, class V
 228
 0.89
chr17_32573755_32573906 0.21 CCL2
 chemokine (C-C motif) ligand 2
 8474
 0.13
chr8_67524543_67525469 0.21 MYBL1
 v-myb avian myeloblastosis viral oncogene homolog-like 1
 136
 0.96
chr17_73008873_73009557 0.21 ICT1
 immature colon carcinoma transcript 1
 446
 0.66
chr3_107818747_107818903 0.21 CD47
 CD47 molecule
 8953
 0.3
chr4_124542421_124542572 0.21 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 221373
 0.02
chr16_68104203_68104354 0.21 ENSG00000221789
 .
 14491
 0.09
chr1_3446831_3447137 0.21 MEGF6
 multiple EGF-like-domains 6
 1028
 0.53
chr3_171758588_171759081 0.21 FNDC3B
 fibronectin type III domain containing 3B
 489
 0.88
chr3_133291490_133292033 0.20 CDV3
 CDV3 homolog (mouse)
 813
 0.65
chrX_48544144_48544295 0.20 WAS
 Wiskott-Aldrich syndrome
 2051
 0.22
chr17_42634478_42634800 0.20 FZD2
 frizzled family receptor 2
 286
 0.91
chr17_75178693_75178860 0.20 SEC14L1
 SEC14-like 1 (S. cerevisiae)
 1657
 0.41
chr12_27038132_27038283 0.20 ASUN
 asunder spermatogenesis regulator
 32460
 0.15
chr3_56817061_56817212 0.20 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
 7451
 0.29
chr18_12703898_12704049 0.20 PSMG2
 proteasome (prosome, macropain) assembly chaperone 2
 951
 0.39
chr22_40743199_40743350 0.20 ADSL
 adenylosuccinate lyase
 738
 0.66
chr13_99740074_99740470 0.19 DOCK9-AS2
 DOCK9 antisense RNA 2 (head to head)
 199
 0.92
chrX_77359847_77360362 0.19 PGK1
 phosphoglycerate kinase 1
 352
 0.91
chr14_64010347_64011034 0.19 CTD-2302E22.4
403
 0.59
chr5_90478735_90478954 0.19 ENSG00000199643
 .
 87700
 0.1
chr12_29310650_29310817 0.19 FAR2
 fatty acyl CoA reductase 2
 8600
 0.26
chr19_54881402_54882266 0.19 LAIR1
 leukocyte-associated immunoglobulin-like receptor 1
 224
 0.88
chr1_32293954_32294105 0.18 SPOCD1
 SPOC domain containing 1
 12377
 0.16
chr10_30990441_30990915 0.18 SVILP1
 supervillin pseudogene 1
 5828
 0.28
chrX_24482692_24483178 0.18 PDK3
 pyruvate dehydrogenase kinase, isozyme 3
 403
 0.88
chr7_30068476_30069002 0.18 PLEKHA8
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
 438
 0.77
chr9_139559538_139560114 0.18 EGFL7
 EGF-like-domain, multiple 7
 418
 0.68
chr19_14358666_14358817 0.18 ENSG00000240803
 .
 34877
 0.12
chr10_63809082_63810748 0.18 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 945
 0.69
chr17_28995985_28996136 0.18 ENSG00000241631
 .
 33733
 0.12
chr15_75082012_75082172 0.17 ENSG00000264386
 .
 994
 0.33
chr3_169381606_169381757 0.17 MECOM
 MDS1 and EVI1 complex locus
 423
 0.83
chr19_46172257_46172467 0.17 GIPR
 gastric inhibitory polypeptide receptor
 847
 0.37
chr20_35823464_35823615 0.17 MROH8
 maestro heat-like repeat family member 8
 15548
 0.18
chr1_184794791_184794942 0.17 ENSG00000252222
 .
 4243
 0.26
chr19_55009541_55009776 0.17 LAIR2
 leukocyte-associated immunoglobulin-like receptor 2
 558
 0.61
chr7_103847754_103848404 0.17 ORC5
 origin recognition complex, subunit 5
 326
 0.94
chr1_28563316_28563564 0.17 ATPIF1
 ATPase inhibitory factor 1
 775
 0.48
chr15_56335461_56335612 0.17 ENSG00000239703
 .
 13357
 0.23
chr9_86593584_86594514 0.16 HNRNPK
 heterogeneous nuclear ribonucleoprotein K
 682
 0.51
chr5_72634404_72634555 0.16 FOXD1
 forkhead box D1
 109873
 0.06
chr7_156400256_156401034 0.16 ENSG00000182648
 .
 2187
 0.32
chr19_926201_926965 0.16 ARID3A
 AT rich interactive domain 3A (BRIGHT-like)
 583
 0.51
chr12_128850300_128850451 0.16 ENSG00000238895
 .
 32602
 0.2
chr12_92534627_92535592 0.16 C12orf79
 chromosome 12 open reading frame 79
 1335
 0.39
chr17_7741127_7741463 0.16 KDM6B
 lysine (K)-specific demethylase 6B
 1927
 0.19
chr3_53288573_53288749 0.16 TKT
 transketolase
 1355
 0.36
chr8_103801561_103801807 0.16 ENSG00000266799
 .
 55737
 0.11
chrX_48937651_48938132 0.16 WDR45
 WD repeat domain 45
 24
 0.81
chrX_75393364_75393724 0.15 PBDC1
 polysaccharide biosynthesis domain containing 1
 669
 0.81
chr10_29771962_29772274 0.15 SVIL
 supervillin
 13329
 0.23
chr19_52553655_52553806 0.15 ZNF432
 zinc finger protein 432
 1657
 0.24
chr15_98511098_98511399 0.15 ARRDC4
 arrestin domain containing 4
 7320
 0.25
chr1_46712530_46712975 0.15 RAD54L
 RAD54-like (S. cerevisiae)
 615
 0.66
chr13_30688522_30688966 0.15 ENSG00000266816
 .
 92092
 0.09
chrX_117767379_117767530 0.15 ENSG00000206862
 .
 63976
 0.12
chr14_70161155_70161306 0.15 SRSF5
 serine/arginine-rich splicing factor 5
 32387
 0.19
chr17_41324442_41324699 0.15 NBR1
 neighbor of BRCA1 gene 1
 1310
 0.36
chr5_179335042_179335255 0.15 TBC1D9B
 TBC1 domain family, member 9B (with GRAM domain)
 289
 0.88
chr5_100236594_100237334 0.15 ST8SIA4
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
 1954
 0.48
chr6_6724392_6724959 0.15 LY86-AS1
 LY86 antisense RNA 1
 101671
 0.08
chr1_43232974_43233556 0.15 C1orf50
 chromosome 1 open reading frame 50
 288
 0.65
chr7_961818_962008 0.14 ADAP1
 ArfGAP with dual PH domains 1
 1387
 0.35
chr3_37156794_37156945 0.14 ENSG00000206645
 .
 22144
 0.14
chr1_231748956_231749347 0.14 LINC00582
 long intergenic non-protein coding RNA 582
 1315
 0.46
chrX_56814440_56814591 0.14 ENSG00000204272
 .
 58823
 0.16
chrX_64888680_64889016 0.14 MSN
 moesin
 1311
 0.61
chr2_176237854_176238005 0.14 ENSG00000221347
 .
 42828
 0.19
chr17_5186908_5187121 0.14 RABEP1
 rabaptin, RAB GTPase binding effector protein 1
 1232
 0.43
chr12_97300286_97300520 0.14 NEDD1
 neural precursor cell expressed, developmentally down-regulated 1
 598
 0.84
chr7_32535632_32536288 0.14 AVL9
 AVL9 homolog (S. cerevisiase)
 638
 0.62
chr6_113201994_113202335 0.14 ENSG00000201386
 .
 90531
 0.1
chr16_77756424_77756870 0.13 NUDT7
 nudix (nucleoside diphosphate linked moiety X)-type motif 7
 205
 0.94
chr4_122722562_122723305 0.13 EXOSC9
 exosome component 9
 185
 0.94
chr2_239800244_239800395 0.13 TWIST2
 twist family bHLH transcription factor 2
 43646
 0.15
chr12_113494281_113494869 0.13 DTX1
 deltex homolog 1 (Drosophila)
 920
 0.55
chr15_57853592_57853743 0.13 GCOM1
 GRINL1A complex locus 1
 30439
 0.16
chr12_58240459_58240718 0.13 CTDSP2
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
 66
 0.95
chr10_75634514_75635168 0.13 CAMK2G
 calcium/calmodulin-dependent protein kinase II gamma
 498
 0.7
chr12_4380598_4381153 0.13 CCND2
 cyclin D2
 2063
 0.27
chr5_168278845_168278996 0.13 ENSG00000202345
 .
 60417
 0.13
chrX_69354363_69354644 0.13 IGBP1
 immunoglobulin (CD79A) binding protein 1
 1190
 0.39
chr8_21776103_21776686 0.13 XPO7
 exportin 7
 786
 0.64
chr2_204192506_204192763 0.13 ABI2
 abl-interactor 2
 308
 0.86
chr1_145516788_145517229 0.13 PEX11B
 peroxisomal biogenesis factor 11 beta
 448
 0.67
chr9_93569627_93569778 0.13 SYK
 spleen tyrosine kinase
 5493
 0.35
chr8_57423628_57423790 0.12 RP11-17A4.2
22052
 0.24
chr6_89791603_89792706 0.12 PNRC1
 proline-rich nuclear receptor coactivator 1
 599
 0.61
chr12_69979635_69980167 0.12 CCT2
 chaperonin containing TCP1, subunit 2 (beta)
 455
 0.72
chr3_63956535_63956875 0.12 ATXN7
 ataxin 7
 3285
 0.2
chr11_10480387_10480598 0.12 AMPD3
 adenosine monophosphate deaminase 3
 2195
 0.31
chr9_98078977_98079489 0.12 FANCC
 Fanconi anemia, complementation group C
 57
 0.98
chr11_72436543_72436694 0.12 ARAP1
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
 1555
 0.28
chr11_66792086_66792237 0.12 SYT12
 synaptotagmin XII
 1345
 0.36
chr1_171750817_171751440 0.12 METTL13
 methyltransferase like 13
 286
 0.89
chr5_133860075_133861084 0.12 JADE2
 jade family PHD finger 2
 576
 0.71
chr10_81204131_81204808 0.12 ZCCHC24
 zinc finger, CCHC domain containing 24
 494
 0.82
chr4_83719416_83720536 0.12 SCD5
 stearoyl-CoA desaturase 5
 34
 0.98
chr19_44281250_44281441 0.12 KCNN4
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
 4064
 0.15
chr21_35445889_35446081 0.12 SLC5A3
 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
 115
 0.57
chr19_16250491_16250727 0.12 CTD-2231E14.8
22
 0.96
chr17_59530124_59530284 0.12 TBX4
 T-box 4
 425
 0.8
chr17_56709506_56709776 0.12 ENSG00000212195
 .
 444
 0.75
chr1_198904942_198905093 0.12 ENSG00000207759
 .
 76735
 0.11
chr10_94608596_94609267 0.12 EXOC6
 exocyst complex component 6
 654
 0.81
chr6_4135067_4135363 0.12 RP3-400B16.4
442
 0.49
chr4_185570944_185571157 0.12 PRIMPOL
 primase and polymerase (DNA-directed)
 171
 0.75
chr16_87985408_87986210 0.12 BANP
 BTG3 associated nuclear protein
 716
 0.69
chrX_47054421_47054572 0.12 UBA1
 ubiquitin-like modifier activating enzyme 1
 1255
 0.34
chr5_134879041_134879292 0.12 NEUROG1
 neurogenin 1
 7527
 0.18
chr19_6108632_6109202 0.11 CTB-66B24.1
416
 0.75
chr19_16296249_16296834 0.11 FAM32A
 family with sequence similarity 32, member A
 275
 0.85
chr2_12859088_12859514 0.11 TRIB2
 tribbles pseudokinase 2
 937
 0.67
chr16_57168681_57168893 0.11 CPNE2
 copine II
 15676
 0.14
chr4_111532497_111532648 0.11 PITX2
 paired-like homeodomain 2
 11635
 0.27
chr5_131826766_131827319 0.11 IRF1
 interferon regulatory factor 1
 552
 0.69
chr11_61185467_61185618 0.11 CPSF7
 cleavage and polyadenylation specific factor 7, 59kDa
 11234
 0.1
chr20_46377193_46377344 0.11 SULF2
 sulfatase 2
 36965
 0.17
chr6_149082246_149082558 0.11 UST
 uronyl-2-sulfotransferase
 13938
 0.3
chr1_103731186_103731553 0.11 COL11A1
 collagen, type XI, alpha 1
 157317
 0.04
chr19_36398950_36399155 0.11 TYROBP
 TYRO protein tyrosine kinase binding protein
 97
 0.93
chr10_82260474_82260649 0.11 RP11-137H2.4
35137
 0.15
chr2_33174000_33174151 0.11 LTBP1
 latent transforming growth factor beta binding protein 1
 1706
 0.38
chr7_100450418_100451115 0.11 SLC12A9
 solute carrier family 12, member 9
 142
 0.81
chr19_872645_872938 0.11 CFD
 complement factor D (adipsin)
 13101
 0.07
chr17_45331851_45332126 0.11 ITGB3
 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
 725
 0.57

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PRDM4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.6 GO:0071305 cellular response to vitamin D(GO:0071305)
0.1 0.2 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0071025 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.1 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0060039 pericardium development(GO:0060039)
0.0 0.0 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.2 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.1 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.4 GO:0001707 mesoderm formation(GO:0001707)
0.0 0.1 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.7 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238) N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.5 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival