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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for PROX1

Z-value: 1.72

Motif logo

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Transcription factors associated with PROX1

Gene Symbol Gene ID Gene Info
PROX1
ENSG00000117707.11 prospero homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_214170628_214170779PROX18240.6604750.452.2e-01Click!
chr1_214156478_214156705PROX1670.975804-0.422.7e-01Click!
chr1_214161166_214161486PROX1400.8456130.245.4e-01Click!
chr1_214170321_214170472PROX15170.8124970.245.4e-01Click!
chr1_214156195_214156346PROX12540.928582-0.166.9e-01Click!

Activity of the PROX1 motif across conditions

Conditions sorted by the z-value of the PROX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr20_8835423_8835602 0.74 ENSG00000201348
 .
 23679
 0.24
chr2_108443697_108444171 0.68 RGPD4
 RANBP2-like and GRIP domain containing 4
 541
 0.87
chr6_42879136_42879323 0.67 PTCRA
 pre T-cell antigen receptor alpha
 4498
 0.12
chr2_108445323_108445660 0.65 RGPD4
 RANBP2-like and GRIP domain containing 4
 2098
 0.48
chr12_49503707_49503930 0.62 LMBR1L
 limb development membrane protein 1-like
 170
 0.89
chr14_63671686_63671939 0.57 RHOJ
 ras homolog family member J
 235
 0.95
chr2_101179059_101179268 0.57 PDCL3
 phosducin-like 3
 11
 0.97
chr9_98412049_98412205 0.54 DKFZP434H0512
 Protein LOC100506667; Putative uncharacterized protein DKFZp434H0512
 122478
 0.05
chr5_88028176_88028469 0.54 CTC-467M3.2
39854
 0.16
chr1_171454288_171454467 0.53 PRRC2C
 proline-rich coiled-coil 2C
 274
 0.88
chr1_120685462_120685613 0.52 ENSG00000207149
 .
 15975
 0.24
chr14_64663537_64663695 0.51 SYNE2
 spectrin repeat containing, nuclear envelope 2
 5295
 0.27
chr14_33194390_33194567 0.49 AKAP6
 A kinase (PRKA) anchor protein 6
 10579
 0.32
chr3_112356800_112357010 0.48 CCDC80
 coiled-coil domain containing 80
 39
 0.98
chr19_16188890_16189584 0.48 TPM4
 tropomyosin 4
 1406
 0.39
chr10_70847938_70848765 0.48 SRGN
 serglycin
 477
 0.82
chrX_153095524_153095861 0.48 PDZD4
 PDZ domain containing 4
 121
 0.93
chr16_4069505_4069681 0.47 RP11-462G12.4
12420
 0.19
chr1_198904372_198904917 0.45 ENSG00000207759
 .
 76362
 0.11
chr9_80262701_80263060 0.45 GNA14
 guanine nucleotide binding protein (G protein), alpha 14
 343
 0.91
chr12_29303115_29303266 0.45 FAR2
 fatty acyl CoA reductase 2
 1057
 0.62
chr5_5419342_5419575 0.44 KIAA0947
 KIAA0947
 3349
 0.39
chr4_1513980_1514175 0.44 NKX1-1
 NK1 homeobox 1
 113958
 0.05
chr2_98280710_98280922 0.43 LINC01125
 long intergenic non-protein coding RNA 1125
 81
 0.64
chr5_156570028_156570441 0.43 MED7
 mediator complex subunit 7
 39
 0.7
chr7_105494613_105494850 0.43 ATXN7L1
 ataxin 7-like 1
 22192
 0.26
chr10_65676733_65676884 0.43 REEP3
 receptor accessory protein 3
 395685
 0.01
chr14_93604450_93604601 0.42 ITPK1
 inositol-tetrakisphosphate 1-kinase
 21860
 0.14
chr20_57426029_57426307 0.42 GNAS-AS1
 GNAS antisense RNA 1
 210
 0.89
chr12_32832317_32832517 0.42 DNM1L
 dynamin 1-like
 147
 0.97
chr8_13370846_13370997 0.42 DLC1
 deleted in liver cancer 1
 1353
 0.48
chr12_94660827_94661045 0.41 PLXNC1
 plexin C1
 4639
 0.19
chr10_98443954_98444105 0.41 PIK3AP1
 phosphoinositide-3-kinase adaptor protein 1
 14661
 0.21
chr7_156432875_156433240 0.41 RNF32
 ring finger protein 32
 82
 0.57
chr20_53092813_53093232 0.40 DOK5
 docking protein 5
 765
 0.8
chr2_70140665_70140816 0.40 ENSG00000238465
 .
 913
 0.4
chr17_63590380_63590998 0.39 AXIN2
 axin 2
 32924
 0.2
chr1_240816316_240816467 0.39 ENSG00000251750
 .
 276
 0.92
chr4_159691379_159691530 0.39 FNIP2
 folliculin interacting protein 2
 1164
 0.49
chr22_42666087_42666289 0.39 TCF20
 transcription factor 20 (AR1)
 54740
 0.11
chr11_47270476_47271047 0.38 NR1H3
 nuclear receptor subfamily 1, group H, member 3
 254
 0.52
chr2_9615136_9615532 0.38 IAH1
 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
 150
 0.95
chr18_22864434_22864674 0.38 CTD-2006O16.2
17536
 0.26
chrX_48659526_48659734 0.38 HDAC6
 histone deacetylase 6
 154
 0.91
chr11_85429273_85429899 0.38 SYTL2
 synaptotagmin-like 2
 55
 0.97
chr12_131364699_131365309 0.37 RAN
 RAN, member RAS oncogene family
 8363
 0.16
chr8_90915010_90915840 0.37 OSGIN2
 oxidative stress induced growth inhibitor family member 2
 436
 0.83
chr22_28181066_28181439 0.37 MN1
 meningioma (disrupted in balanced translocation) 1
 16234
 0.25
chr12_68759315_68759468 0.37 MDM1
 Mdm1 nuclear protein homolog (mouse)
 33230
 0.21
chr2_231084808_231085018 0.37 SP110
 SP110 nuclear body protein
 86
 0.97
chr16_51184162_51184313 0.36 SALL1
 spalt-like transcription factor 1
 271
 0.87
chr5_157893628_157893779 0.36 ENSG00000222626
 .
 489739
 0.0
chr11_120468534_120468685 0.36 GRIK4
 glutamate receptor, ionotropic, kainate 4
 33466
 0.21
chr8_116681536_116682020 0.36 TRPS1
 trichorhinophalangeal syndrome I
 68
 0.99
chrY_15591562_15591785 0.35 UTY
 ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
 122
 0.98
chr12_11323609_11324192 0.35 RP11-785H5.2
52
 0.97
chr2_107084278_107084429 0.35 RGPD3
 RANBP2-like and GRIP domain containing 3
 473
 0.82
chr7_5465601_5465997 0.35 TNRC18
 trinucleotide repeat containing 18
 754
 0.57
chr6_127835815_127835966 0.35 SOGA3
 SOGA family member 3
 1869
 0.42
chr9_35691198_35691509 0.35 TPM2
 tropomyosin 2 (beta)
 336
 0.72
chr6_16586317_16586686 0.35 ENSG00000265642
 .
 157747
 0.04
chr6_131382971_131383273 0.34 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 594
 0.84
chr15_26105615_26105919 0.34 ATP10A
 ATPase, class V, type 10A
 2588
 0.28
chr12_7848081_7848232 0.34 GDF3
 growth differentiation factor 3
 216
 0.91
chr17_40424420_40424618 0.34 AC003104.1
182
 0.9
chrX_128974400_128974551 0.34 ZDHHC9
 zinc finger, DHHC-type containing 9
 1325
 0.44
chr12_72665965_72666270 0.34 ENSG00000236333
 .
 189
 0.69
chr14_81931293_81931471 0.34 STON2
 stonin 2
 28573
 0.23
chr19_1367548_1367699 0.34 AC004623.2
9614
 0.08
chr2_109151249_109151412 0.34 LIMS1
 LIM and senescent cell antigen-like domains 1
 418
 0.64
chr2_102654423_102654574 0.34 IL1R1
 interleukin 1 receptor, type I
 26506
 0.19
chr16_19728705_19729100 0.34 KNOP1
 lysine-rich nucleolar protein 1
 551
 0.5
chr13_24612503_24612731 0.34 SPATA13
 spermatogenesis associated 13
 58673
 0.12
chr2_108444784_108444988 0.34 RGPD4
 RANBP2-like and GRIP domain containing 4
 1493
 0.58
chr4_79697241_79697410 0.33 RP11-109G23.3
198
 0.5
chr9_93570933_93571084 0.33 SYK
 spleen tyrosine kinase
 6799
 0.34
chr7_128809270_128809816 0.33 RP11-286H14.6
1490
 0.31
chr20_31260807_31260958 0.33 COMMD7
 COMM domain containing 7
 70330
 0.08
chr3_73769050_73769270 0.33 PDZRN3
 PDZ domain containing ring finger 3
 95069
 0.08
chr16_27412028_27412277 0.33 IL21R
 interleukin 21 receptor
 1331
 0.47
chr13_106704671_106704822 0.33 ENSG00000222643
 .
 75974
 0.12
chr18_34273309_34273594 0.33 FHOD3
 formin homology 2 domain containing 3
 25069
 0.22
chr8_22342638_22342826 0.32 PPP3CC
 protein phosphatase 3, catalytic subunit, gamma isozyme
 9627
 0.15
chr14_90320865_90321016 0.32 EFCAB11
 EF-hand calcium binding domain 11
 99927
 0.07
chr6_114405713_114405864 0.32 RP3-399L15.3
55
 0.98
chr11_116658822_116659171 0.32 ZNF259
 zinc finger protein 259
 230
 0.87
chr5_88178054_88178448 0.32 MEF2C
 myocyte enhancer factor 2C
 713
 0.52
chr3_159706229_159707171 0.32 IL12A
 interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
 41
 0.98
chr14_92941981_92942132 0.32 SLC24A4
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
 36348
 0.18
chr12_85674997_85675148 0.32 ALX1
 ALX homeobox 1
 1187
 0.65
chr17_772598_772950 0.32 NXN
 nucleoredoxin
 5423
 0.17
chr5_149380800_149381041 0.32 TIGD6
 tigger transposable element derived 6
 190
 0.82
chr8_21770420_21771232 0.32 DOK2
 docking protein 2, 56kDa
 348
 0.88
chr1_179335166_179335697 0.31 AXDND1
 axonemal dynein light chain domain containing 1
 324
 0.87
chr7_1578236_1578521 0.31 MAFK
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
 34
 0.97
chr20_58637452_58637603 0.31 C20orf197
 chromosome 20 open reading frame 197
 6547
 0.27
chr7_130645974_130646155 0.31 LINC-PINT
 long intergenic non-protein coding RNA, p53 induced transcript
 22804
 0.23
chr21_34863285_34863752 0.31 DNAJC28
 DnaJ (Hsp40) homolog, subfamily C, member 28
 262
 0.87
chr4_7832917_7833068 0.31 AFAP1
 actin filament associated protein 1
 40817
 0.16
chr15_77708252_77708450 0.31 PEAK1
 pseudopodium-enriched atypical kinase 1
 4091
 0.26
chr1_43147265_43147870 0.31 YBX1
 Y box binding protein 1
 531
 0.75
chr4_56047702_56047853 0.31 ENSG00000239545
 .
 34302
 0.16
chr1_202775672_202775981 0.31 KDM5B
 lysine (K)-specific demethylase 5B
 601
 0.63
chr12_123284077_123284228 0.31 CCDC62
 coiled-coil domain containing 62
 18365
 0.13
chr11_6411170_6411483 0.30 SMPD1
 sphingomyelin phosphodiesterase 1, acid lysosomal
 329
 0.85
chr4_95374257_95374632 0.30 PDLIM5
 PDZ and LIM domain 5
 1350
 0.6
chr11_72504918_72505117 0.30 STARD10
 StAR-related lipid transfer (START) domain containing 10
 291
 0.55
chrX_149905180_149905331 0.30 MTMR1
 myotubularin related protein 1
 18106
 0.25
chr7_87849519_87850007 0.30 SRI
 sorcin
 369
 0.77
chr19_53324249_53324569 0.30 ZNF28
 zinc finger protein 28
 476
 0.77
chr6_17212771_17212995 0.30 RBM24
 RNA binding motif protein 24
 68694
 0.13
chr4_71702728_71702883 0.29 GRSF1
 G-rich RNA sequence binding factor 1
 1913
 0.26
chr2_114341836_114342054 0.29 WASH2P
 WAS protein family homolog 2 pseudogene
 281
 0.85
chr6_39759892_39760124 0.29 DAAM2
 dishevelled associated activator of morphogenesis 2
 134
 0.98
chr2_85536945_85537100 0.29 ENSG00000221579
 .
 10865
 0.11
chr6_117997172_117997416 0.29 NUS1
 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
 629
 0.81
chr5_172296489_172296640 0.29 ERGIC1
 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
 35150
 0.14
chrX_108975342_108975600 0.29 ACSL4
 acyl-CoA synthetase long-chain family member 4
 971
 0.63
chr2_26401607_26402234 0.29 GAREML
 GRB2 associated, regulator of MAPK1-like
 1665
 0.38
chr8_26370640_26370791 0.29 PNMA2
 paraneoplastic Ma antigen 2
 893
 0.46
chr4_154179778_154180018 0.29 TRIM2
 tripartite motif containing 2
 1336
 0.41
chr21_18983747_18983987 0.29 BTG3
 BTG family, member 3
 1295
 0.49
chr14_21540226_21540377 0.29 NDRG2
 NDRG family member 2
 1270
 0.23
chr20_34208992_34209143 0.29 SPAG4
 sperm associated antigen 4
 1560
 0.25
chr1_3563687_3563838 0.29 WRAP73
 WD repeat containing, antisense to TP73
 2828
 0.16
chr1_207226273_207226577 0.29 YOD1
 YOD1 deubiquitinase
 100
 0.61
chr19_42745746_42746329 0.29 GSK3A
 glycogen synthase kinase 3 alpha
 8
 0.92
chr9_93970956_93971107 0.29 AUH
 AU RNA binding protein/enoyl-CoA hydratase
 153146
 0.04
chr5_33892545_33892868 0.28 ADAMTS12
 ADAM metallopeptidase with thrombospondin type 1 motif, 12
 409
 0.85
chr17_7477286_7477712 0.28 EIF4A1
 eukaryotic translation initiation factor 4A1
 337
 0.48
chr7_136831101_136831290 0.28 hsa-mir-490
 hsa-mir-490
 17822
 0.28
chr10_31996328_31996772 0.28 ENSG00000222412
 .
 48514
 0.18
chr8_123439435_123439791 0.28 ENSG00000238901
 .
 243917
 0.02
chr9_14098246_14098397 0.28 NFIB
 nuclear factor I/B
 82470
 0.11
chr10_31446412_31446660 0.28 ENSG00000263578
 .
 91560
 0.08
chr1_154150371_154150685 0.28 TPM3
 tropomyosin 3
 131
 0.92
chr10_13343824_13344114 0.28 PHYH
 phytanoyl-CoA 2-hydroxylase
 443
 0.81
chr11_123374923_123375196 0.28 GRAMD1B
 GRAM domain containing 1B
 21285
 0.22
chr19_15752519_15752670 0.28 CYP4F3
 cytochrome P450, family 4, subfamily F, polypeptide 3
 475
 0.8
chr2_201577972_201578363 0.28 AOX1
 aldehyde oxidase 1
 50537
 0.11
chr11_35965857_35966431 0.28 LDLRAD3
 low density lipoprotein receptor class A domain containing 3
 516
 0.78
chr3_99369768_99369919 0.28 COL8A1
 collagen, type VIII, alpha 1
 12389
 0.25
chr5_180234522_180234938 0.28 MGAT1
 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
 1028
 0.5
chr11_65121571_65122031 0.28 TIGD3
 tigger transposable element derived 3
 437
 0.71
chr19_13044137_13044551 0.28 FARSA
 phenylalanyl-tRNA synthetase, alpha subunit
 150
 0.86
chr1_42801336_42801700 0.27 FOXJ3
 forkhead box J3
 30
 0.97
chr11_60611740_60611891 0.27 RP11-804A23.2
1377
 0.22
chr12_49525985_49526136 0.27 RP11-386G11.10
567
 0.36
chr13_101173468_101173697 0.27 PCCA
 propionyl CoA carboxylase, alpha polypeptide
 5901
 0.19
chr4_134071254_134071890 0.27 PCDH10
 protocadherin 10
 1102
 0.7
chr7_5184079_5184242 0.27 ZNF890P
 zinc finger protein 890, pseudogene
 16734
 0.17
chr16_16092499_16092731 0.27 ABCC1
 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
 11098
 0.24
chr7_142490891_142491049 0.26 PRSS3P2
 protease, serine, 3 pseudogene 2
 9839
 0.18
chr6_8101764_8102105 0.26 EEF1E1
 eukaryotic translation elongation factor 1 epsilon 1
 345
 0.91
chr3_46035020_46035171 0.26 FYCO1
 FYVE and coiled-coil domain containing 1
 2212
 0.3
chr6_36952765_36953398 0.26 MTCH1
 mitochondrial carrier 1
 752
 0.63
chr4_141419201_141419573 0.26 RP11-542P2.1
 Glycosyltransferase 54 domain-containing protein
 11
 0.98
chr11_73019949_73020282 0.26 RP11-800A3.7
291
 0.76
chr12_62860096_62860418 0.26 MON2
 MON2 homolog (S. cerevisiae)
 340
 0.89
chr1_150779976_150780304 0.26 CTSK
 cathepsin K
 230
 0.9
chrX_120337999_120338191 0.26 ENSG00000212032
 .
 128397
 0.05
chr3_8359644_8359795 0.26 ENSG00000253081
 .
 46615
 0.19
chr2_208482240_208482391 0.26 METTL21A
 methyltransferase like 21A
 6789
 0.2
chr8_10696654_10696859 0.26 PINX1
 PIN2/TERF1 interacting, telomerase inhibitor 1
 525
 0.45
chr2_232826006_232826949 0.26 DIS3L2
 DIS3 mitotic control homolog (S. cerevisiae)-like 2
 59
 0.98
chr12_21926599_21927146 0.26 KCNJ8
 potassium inwardly-rectifying channel, subfamily J, member 8
 883
 0.57
chr19_32006893_32007044 0.26 ENSG00000252780
 .
 139399
 0.05
chr3_14513811_14513962 0.25 SLC6A6
 solute carrier family 6 (neurotransmitter transporter), member 6
 136
 0.97
chr22_41844915_41845188 0.25 TOB2
 transducer of ERBB2, 2
 2024
 0.25
chr19_3186026_3186436 0.25 NCLN
 nicalin
 297
 0.85
chr3_47324358_47324645 0.25 KLHL18
 kelch-like family member 18
 64
 0.64
chr6_35635788_35636125 0.25 ENSG00000265527
 .
 3390
 0.18
chr5_131131799_131132359 0.25 FNIP1
 folliculin interacting protein 1
 535
 0.5
chr5_111510621_111510791 0.25 CTC-459M5.1
1439
 0.4
chr1_1293449_1293856 0.25 MXRA8
 matrix-remodelling associated 8
 263
 0.78
chr7_102157613_102157887 0.25 RASA4B
 RAS p21 protein activator 4B
 407
 0.7
chr20_55936781_55936932 0.25 MTRNR2L3
 MT-RNR2-like 3
 1978
 0.23
chr1_52083072_52083707 0.25 OSBPL9
 oxysterol binding protein-like 9
 608
 0.77
chr2_198120374_198120867 0.25 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 46623
 0.12
chr10_14879452_14879992 0.25 CDNF
 cerebral dopamine neurotrophic factor
 349
 0.56
chr2_175854784_175854957 0.25 ENSG00000201425
 .
 12339
 0.15
chr9_35646178_35646825 0.25 RP11-331F9.4
234
 0.81
chr11_5711907_5712253 0.25 TRIM22
 tripartite motif containing 22
 177
 0.91
chr7_91510205_91510446 0.25 MTERF
 mitochondrial transcription termination factor
 291
 0.94
chr12_96529900_96530051 0.25 ENSG00000266889
 .
 33948
 0.15
chr17_16472637_16472847 0.25 ZNF287
 zinc finger protein 287
 222
 0.93
chr11_2468791_2468942 0.25 KCNQ1
 potassium voltage-gated channel, KQT-like subfamily, member 1
 2645
 0.21
chr18_47793998_47794618 0.25 CCDC11
 coiled-coil domain containing 11
 1416
 0.36
chr15_80445342_80445551 0.25 FAH
 fumarylacetoacetate hydrolase (fumarylacetoacetase)
 207
 0.95
chr11_77530634_77531102 0.25 RSF1
 remodeling and spacing factor 1
 884
 0.42
chr5_68903659_68903865 0.24 RP11-848G14.2
10378
 0.18
chr16_87498544_87498873 0.24 ZCCHC14
 zinc finger, CCHC domain containing 14
 26943
 0.15
chr17_1686722_1687045 0.24 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
 11870
 0.11
chr14_50863724_50864050 0.24 CDKL1
 cyclin-dependent kinase-like 1 (CDC2-related kinase)
 235
 0.94
chr3_160281811_160282588 0.24 KPNA4
 karyopherin alpha 4 (importin alpha 3)
 1177
 0.52
chr1_168329622_168329773 0.24 ENSG00000207974
 .
 15065
 0.23
chr17_7464555_7465071 0.24 SENP3
 SUMO1/sentrin/SMT3 specific peptidase 3
 459
 0.5
chr20_48294953_48295215 0.24 B4GALT5
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
 35331
 0.15
chr7_112578777_112579037 0.24 C7orf60
 chromosome 7 open reading frame 60
 766
 0.77
chr6_149637823_149638060 0.24 TAB2
 TGF-beta activated kinase 1/MAP3K7 binding protein 2
 1122
 0.52

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of PROX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.5 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.3 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.1 0.3 GO:0072033 renal vesicle formation(GO:0072033)
0.1 0.4 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.3 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.3 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.2 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.4 GO:1903020 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.2 GO:2000189 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.3 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.2 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.1 0.2 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1 0.2 GO:0006591 ornithine metabolic process(GO:0006591)
0.1 0.2 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.1 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.2 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0050942 regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636) regulation of pigment cell differentiation(GO:0050932) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.2 GO:0051458 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.4 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.2 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.2 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.2 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.2 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.2 GO:0000959 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.1 GO:0021610 cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.0 GO:0021561 facial nerve development(GO:0021561)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.2 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.1 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.4 GO:0043631 RNA polyadenylation(GO:0043631)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0071025 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0031645 negative regulation of neurological system process(GO:0031645) negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.0 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.2 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.3 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0048194 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.0 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.0 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.0 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.0 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.0 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0090181 regulation of cholesterol metabolic process(GO:0090181)
0.0 0.0 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.0 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.0 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.0 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.2 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.0 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.2 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.2 GO:0048489 synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0 0.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0072698 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.1 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.0 0.1 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.0 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.1 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701) regulation of gastric acid secretion(GO:0060453)
0.0 0.1 GO:0003341 cilium movement(GO:0003341)
0.0 0.1 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.0 GO:1901796 regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516) regulation of signal transduction by p53 class mediator(GO:1901796)
0.0 0.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.6 GO:0010827 regulation of glucose transport(GO:0010827)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.2 GO:0032570 response to progesterone(GO:0032570)
0.0 0.0 GO:0051307 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.1 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.0 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0009414 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.1 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.0 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.0 0.0 GO:0052509 modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0 0.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0033483 gas homeostasis(GO:0033483)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0019682 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.4 GO:0042629 mast cell granule(GO:0042629)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.3 GO:0010369 chromocenter(GO:0010369)
0.1 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0016235 aggresome(GO:0016235)
0.1 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0016342 catenin complex(GO:0016342)
0.1 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 1.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.0 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.0 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.0 GO:0043656 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.5 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.5 GO:0031674 I band(GO:0031674)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.0 GO:0042405 nuclear inclusion body(GO:0042405)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1 0.2 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.3 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.1 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.3 GO:0048156 tau protein binding(GO:0048156)
0.1 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.2 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0032357 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.3 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.0 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.0 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.5 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.6 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.8 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.0 GO:0002060 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0017069 snRNA binding(GO:0017069)
0.0 0.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.0 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.2 GO:0016878 acid-thiol ligase activity(GO:0016878)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.6 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.0 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME ADAPTIVE IMMUNE SYSTEM Genes involved in Adaptive Immune System
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane