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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PROX1

Z-value: 1.72

Motif logo

Transcription factors associated with PROX1

Gene Symbol	Gene ID	Gene Info
PROX1 Ensembl NCBI GeneCards UniProt	ENSG00000117707.11	PROX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
PROX1	chr1_214170628_214170779	824	0.660475	0.45	2.2e-01	Click!
PROX1	chr1_214156478_214156705	67	0.975804	-0.42	2.7e-01	Click!
PROX1	chr1_214161166_214161486	40	0.845613	0.24	5.4e-01	Click!
PROX1	chr1_214170321_214170472	517	0.812497	0.24	5.4e-01	Click!
PROX1	chr1_214156195_214156346	254	0.928582	-0.16	6.9e-01	Click!

Activity of the PROX1 motif across conditions

Conditions sorted by the z-value of the PROX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr20_8835423_8835602	0.74	ENSG00000201348	.	23679	0.24
chr2_108443697_108444171	0.68	RGPD4	RANBP2-like and GRIP domain containing 4	541	0.87
chr6_42879136_42879323	0.67	PTCRA	pre T-cell antigen receptor alpha	4498	0.12
chr2_108445323_108445660	0.65	RGPD4	RANBP2-like and GRIP domain containing 4	2098	0.48
chr12_49503707_49503930	0.62	LMBR1L	limb development membrane protein 1-like	170	0.89
chr14_63671686_63671939	0.57	RHOJ	ras homolog family member J	235	0.95
chr2_101179059_101179268	0.57	PDCL3	phosducin-like 3	11	0.97
chr9_98412049_98412205	0.54	DKFZP434H0512	Protein LOC100506667; Putative uncharacterized protein DKFZp434H0512	122478	0.05
chr5_88028176_88028469	0.54	CTC-467M3.2		39854	0.16
chr1_171454288_171454467	0.53	PRRC2C	proline-rich coiled-coil 2C	274	0.88
chr1_120685462_120685613	0.52	ENSG00000207149	.	15975	0.24
chr14_64663537_64663695	0.51	SYNE2	spectrin repeat containing, nuclear envelope 2	5295	0.27
chr14_33194390_33194567	0.49	AKAP6	A kinase (PRKA) anchor protein 6	10579	0.32
chr3_112356800_112357010	0.48	CCDC80	coiled-coil domain containing 80	39	0.98
chr19_16188890_16189584	0.48	TPM4	tropomyosin 4	1406	0.39
chr10_70847938_70848765	0.48	SRGN	serglycin	477	0.82
chrX_153095524_153095861	0.48	PDZD4	PDZ domain containing 4	121	0.93
chr16_4069505_4069681	0.47	RP11-462G12.4		12420	0.19
chr1_198904372_198904917	0.45	ENSG00000207759	.	76362	0.11
chr9_80262701_80263060	0.45	GNA14	guanine nucleotide binding protein (G protein), alpha 14	343	0.91
chr12_29303115_29303266	0.45	FAR2	fatty acyl CoA reductase 2	1057	0.62
chr5_5419342_5419575	0.44	KIAA0947	KIAA0947	3349	0.39
chr4_1513980_1514175	0.44	NKX1-1	NK1 homeobox 1	113958	0.05
chr2_98280710_98280922	0.43	LINC01125	long intergenic non-protein coding RNA 1125	81	0.64
chr5_156570028_156570441	0.43	MED7	mediator complex subunit 7	39	0.7
chr7_105494613_105494850	0.43	ATXN7L1	ataxin 7-like 1	22192	0.26
chr10_65676733_65676884	0.43	REEP3	receptor accessory protein 3	395685	0.01
chr14_93604450_93604601	0.42	ITPK1	inositol-tetrakisphosphate 1-kinase	21860	0.14
chr20_57426029_57426307	0.42	GNAS-AS1	GNAS antisense RNA 1	210	0.89
chr12_32832317_32832517	0.42	DNM1L	dynamin 1-like	147	0.97
chr8_13370846_13370997	0.42	DLC1	deleted in liver cancer 1	1353	0.48
chr12_94660827_94661045	0.41	PLXNC1	plexin C1	4639	0.19
chr10_98443954_98444105	0.41	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	14661	0.21
chr7_156432875_156433240	0.41	RNF32	ring finger protein 32	82	0.57
chr20_53092813_53093232	0.40	DOK5	docking protein 5	765	0.8
chr2_70140665_70140816	0.40	ENSG00000238465	.	913	0.4
chr17_63590380_63590998	0.39	AXIN2	axin 2	32924	0.2
chr1_240816316_240816467	0.39	ENSG00000251750	.	276	0.92
chr4_159691379_159691530	0.39	FNIP2	folliculin interacting protein 2	1164	0.49
chr22_42666087_42666289	0.39	TCF20	transcription factor 20 (AR1)	54740	0.11
chr11_47270476_47271047	0.38	NR1H3	nuclear receptor subfamily 1, group H, member 3	254	0.52
chr2_9615136_9615532	0.38	IAH1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)	150	0.95
chr18_22864434_22864674	0.38	CTD-2006O16.2		17536	0.26
chrX_48659526_48659734	0.38	HDAC6	histone deacetylase 6	154	0.91
chr11_85429273_85429899	0.38	SYTL2	synaptotagmin-like 2	55	0.97
chr12_131364699_131365309	0.37	RAN	RAN, member RAS oncogene family	8363	0.16
chr8_90915010_90915840	0.37	OSGIN2	oxidative stress induced growth inhibitor family member 2	436	0.83
chr22_28181066_28181439	0.37	MN1	meningioma (disrupted in balanced translocation) 1	16234	0.25
chr12_68759315_68759468	0.37	MDM1	Mdm1 nuclear protein homolog (mouse)	33230	0.21
chr2_231084808_231085018	0.37	SP110	SP110 nuclear body protein	86	0.97
chr16_51184162_51184313	0.36	SALL1	spalt-like transcription factor 1	271	0.87
chr5_157893628_157893779	0.36	ENSG00000222626	.	489739	0.0
chr11_120468534_120468685	0.36	GRIK4	glutamate receptor, ionotropic, kainate 4	33466	0.21
chr8_116681536_116682020	0.36	TRPS1	trichorhinophalangeal syndrome I	68	0.99
chrY_15591562_15591785	0.35	UTY	ubiquitously transcribed tetratricopeptide repeat containing, Y-linked	122	0.98
chr12_11323609_11324192	0.35	RP11-785H5.2		52	0.97
chr2_107084278_107084429	0.35	RGPD3	RANBP2-like and GRIP domain containing 3	473	0.82
chr7_5465601_5465997	0.35	TNRC18	trinucleotide repeat containing 18	754	0.57
chr6_127835815_127835966	0.35	SOGA3	SOGA family member 3	1869	0.42
chr9_35691198_35691509	0.35	TPM2	tropomyosin 2 (beta)	336	0.72
chr6_16586317_16586686	0.35	ENSG00000265642	.	157747	0.04
chr6_131382971_131383273	0.34	EPB41L2	erythrocyte membrane protein band 4.1-like 2	594	0.84
chr15_26105615_26105919	0.34	ATP10A	ATPase, class V, type 10A	2588	0.28
chr12_7848081_7848232	0.34	GDF3	growth differentiation factor 3	216	0.91
chr17_40424420_40424618	0.34	AC003104.1		182	0.9
chrX_128974400_128974551	0.34	ZDHHC9	zinc finger, DHHC-type containing 9	1325	0.44
chr12_72665965_72666270	0.34	ENSG00000236333	.	189	0.69
chr14_81931293_81931471	0.34	STON2	stonin 2	28573	0.23
chr19_1367548_1367699	0.34	AC004623.2		9614	0.08
chr2_109151249_109151412	0.34	LIMS1	LIM and senescent cell antigen-like domains 1	418	0.64
chr2_102654423_102654574	0.34	IL1R1	interleukin 1 receptor, type I	26506	0.19
chr16_19728705_19729100	0.34	KNOP1	lysine-rich nucleolar protein 1	551	0.5
chr13_24612503_24612731	0.34	SPATA13	spermatogenesis associated 13	58673	0.12
chr2_108444784_108444988	0.34	RGPD4	RANBP2-like and GRIP domain containing 4	1493	0.58
chr4_79697241_79697410	0.33	RP11-109G23.3		198	0.5
chr9_93570933_93571084	0.33	SYK	spleen tyrosine kinase	6799	0.34
chr7_128809270_128809816	0.33	RP11-286H14.6		1490	0.31
chr20_31260807_31260958	0.33	COMMD7	COMM domain containing 7	70330	0.08
chr3_73769050_73769270	0.33	PDZRN3	PDZ domain containing ring finger 3	95069	0.08
chr16_27412028_27412277	0.33	IL21R	interleukin 21 receptor	1331	0.47
chr13_106704671_106704822	0.33	ENSG00000222643	.	75974	0.12
chr18_34273309_34273594	0.33	FHOD3	formin homology 2 domain containing 3	25069	0.22
chr8_22342638_22342826	0.32	PPP3CC	protein phosphatase 3, catalytic subunit, gamma isozyme	9627	0.15
chr14_90320865_90321016	0.32	EFCAB11	EF-hand calcium binding domain 11	99927	0.07
chr6_114405713_114405864	0.32	RP3-399L15.3		55	0.98
chr11_116658822_116659171	0.32	ZNF259	zinc finger protein 259	230	0.87
chr5_88178054_88178448	0.32	MEF2C	myocyte enhancer factor 2C	713	0.52
chr3_159706229_159707171	0.32	IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	41	0.98
chr14_92941981_92942132	0.32	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	36348	0.18
chr12_85674997_85675148	0.32	ALX1	ALX homeobox 1	1187	0.65
chr17_772598_772950	0.32	NXN	nucleoredoxin	5423	0.17
chr5_149380800_149381041	0.32	TIGD6	tigger transposable element derived 6	190	0.82
chr8_21770420_21771232	0.32	DOK2	docking protein 2, 56kDa	348	0.88
chr1_179335166_179335697	0.31	AXDND1	axonemal dynein light chain domain containing 1	324	0.87
chr7_1578236_1578521	0.31	MAFK	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	34	0.97
chr20_58637452_58637603	0.31	C20orf197	chromosome 20 open reading frame 197	6547	0.27
chr7_130645974_130646155	0.31	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	22804	0.23
chr21_34863285_34863752	0.31	DNAJC28	DnaJ (Hsp40) homolog, subfamily C, member 28	262	0.87
chr4_7832917_7833068	0.31	AFAP1	actin filament associated protein 1	40817	0.16
chr15_77708252_77708450	0.31	PEAK1	pseudopodium-enriched atypical kinase 1	4091	0.26
chr1_43147265_43147870	0.31	YBX1	Y box binding protein 1	531	0.75
chr4_56047702_56047853	0.31	ENSG00000239545	.	34302	0.16
chr1_202775672_202775981	0.31	KDM5B	lysine (K)-specific demethylase 5B	601	0.63
chr12_123284077_123284228	0.31	CCDC62	coiled-coil domain containing 62	18365	0.13
chr11_6411170_6411483	0.30	SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	329	0.85
chr4_95374257_95374632	0.30	PDLIM5	PDZ and LIM domain 5	1350	0.6
chr11_72504918_72505117	0.30	STARD10	StAR-related lipid transfer (START) domain containing 10	291	0.55
chrX_149905180_149905331	0.30	MTMR1	myotubularin related protein 1	18106	0.25
chr7_87849519_87850007	0.30	SRI	sorcin	369	0.77
chr19_53324249_53324569	0.30	ZNF28	zinc finger protein 28	476	0.77
chr6_17212771_17212995	0.30	RBM24	RNA binding motif protein 24	68694	0.13
chr4_71702728_71702883	0.29	GRSF1	G-rich RNA sequence binding factor 1	1913	0.26
chr2_114341836_114342054	0.29	WASH2P	WAS protein family homolog 2 pseudogene	281	0.85
chr6_39759892_39760124	0.29	DAAM2	dishevelled associated activator of morphogenesis 2	134	0.98
chr2_85536945_85537100	0.29	ENSG00000221579	.	10865	0.11
chr6_117997172_117997416	0.29	NUS1	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	629	0.81
chr5_172296489_172296640	0.29	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	35150	0.14
chrX_108975342_108975600	0.29	ACSL4	acyl-CoA synthetase long-chain family member 4	971	0.63
chr2_26401607_26402234	0.29	GAREML	GRB2 associated, regulator of MAPK1-like	1665	0.38
chr8_26370640_26370791	0.29	PNMA2	paraneoplastic Ma antigen 2	893	0.46
chr4_154179778_154180018	0.29	TRIM2	tripartite motif containing 2	1336	0.41
chr21_18983747_18983987	0.29	BTG3	BTG family, member 3	1295	0.49
chr14_21540226_21540377	0.29	NDRG2	NDRG family member 2	1270	0.23
chr20_34208992_34209143	0.29	SPAG4	sperm associated antigen 4	1560	0.25
chr1_3563687_3563838	0.29	WRAP73	WD repeat containing, antisense to TP73	2828	0.16
chr1_207226273_207226577	0.29	YOD1	YOD1 deubiquitinase	100	0.61
chr19_42745746_42746329	0.29	GSK3A	glycogen synthase kinase 3 alpha	8	0.92
chr9_93970956_93971107	0.29	AUH	AU RNA binding protein/enoyl-CoA hydratase	153146	0.04
chr5_33892545_33892868	0.28	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12	409	0.85
chr17_7477286_7477712	0.28	EIF4A1	eukaryotic translation initiation factor 4A1	337	0.48
chr7_136831101_136831290	0.28	hsa-mir-490	hsa-mir-490	17822	0.28
chr10_31996328_31996772	0.28	ENSG00000222412	.	48514	0.18
chr8_123439435_123439791	0.28	ENSG00000238901	.	243917	0.02
chr9_14098246_14098397	0.28	NFIB	nuclear factor I/B	82470	0.11
chr10_31446412_31446660	0.28	ENSG00000263578	.	91560	0.08
chr1_154150371_154150685	0.28	TPM3	tropomyosin 3	131	0.92
chr10_13343824_13344114	0.28	PHYH	phytanoyl-CoA 2-hydroxylase	443	0.81
chr11_123374923_123375196	0.28	GRAMD1B	GRAM domain containing 1B	21285	0.22
chr19_15752519_15752670	0.28	CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	475	0.8
chr2_201577972_201578363	0.28	AOX1	aldehyde oxidase 1	50537	0.11
chr11_35965857_35966431	0.28	LDLRAD3	low density lipoprotein receptor class A domain containing 3	516	0.78
chr3_99369768_99369919	0.28	COL8A1	collagen, type VIII, alpha 1	12389	0.25
chr5_180234522_180234938	0.28	MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	1028	0.5
chr11_65121571_65122031	0.28	TIGD3	tigger transposable element derived 3	437	0.71
chr19_13044137_13044551	0.28	FARSA	phenylalanyl-tRNA synthetase, alpha subunit	150	0.86
chr1_42801336_42801700	0.27	FOXJ3	forkhead box J3	30	0.97
chr11_60611740_60611891	0.27	RP11-804A23.2		1377	0.22
chr12_49525985_49526136	0.27	RP11-386G11.10		567	0.36
chr13_101173468_101173697	0.27	PCCA	propionyl CoA carboxylase, alpha polypeptide	5901	0.19
chr4_134071254_134071890	0.27	PCDH10	protocadherin 10	1102	0.7
chr7_5184079_5184242	0.27	ZNF890P	zinc finger protein 890, pseudogene	16734	0.17
chr16_16092499_16092731	0.27	ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	11098	0.24
chr7_142490891_142491049	0.26	PRSS3P2	protease, serine, 3 pseudogene 2	9839	0.18
chr6_8101764_8102105	0.26	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1	345	0.91
chr3_46035020_46035171	0.26	FYCO1	FYVE and coiled-coil domain containing 1	2212	0.3
chr6_36952765_36953398	0.26	MTCH1	mitochondrial carrier 1	752	0.63
chr4_141419201_141419573	0.26	RP11-542P2.1	Glycosyltransferase 54 domain-containing protein	11	0.98
chr11_73019949_73020282	0.26	RP11-800A3.7		291	0.76
chr12_62860096_62860418	0.26	MON2	MON2 homolog (S. cerevisiae)	340	0.89
chr1_150779976_150780304	0.26	CTSK	cathepsin K	230	0.9
chrX_120337999_120338191	0.26	ENSG00000212032	.	128397	0.05
chr3_8359644_8359795	0.26	ENSG00000253081	.	46615	0.19
chr2_208482240_208482391	0.26	METTL21A	methyltransferase like 21A	6789	0.2
chr8_10696654_10696859	0.26	PINX1	PIN2/TERF1 interacting, telomerase inhibitor 1	525	0.45
chr2_232826006_232826949	0.26	DIS3L2	DIS3 mitotic control homolog (S. cerevisiae)-like 2	59	0.98
chr12_21926599_21927146	0.26	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8	883	0.57
chr19_32006893_32007044	0.26	ENSG00000252780	.	139399	0.05
chr3_14513811_14513962	0.25	SLC6A6	solute carrier family 6 (neurotransmitter transporter), member 6	136	0.97
chr22_41844915_41845188	0.25	TOB2	transducer of ERBB2, 2	2024	0.25
chr19_3186026_3186436	0.25	NCLN	nicalin	297	0.85
chr3_47324358_47324645	0.25	KLHL18	kelch-like family member 18	64	0.64
chr6_35635788_35636125	0.25	ENSG00000265527	.	3390	0.18
chr5_131131799_131132359	0.25	FNIP1	folliculin interacting protein 1	535	0.5
chr5_111510621_111510791	0.25	CTC-459M5.1		1439	0.4
chr1_1293449_1293856	0.25	MXRA8	matrix-remodelling associated 8	263	0.78
chr7_102157613_102157887	0.25	RASA4B	RAS p21 protein activator 4B	407	0.7
chr20_55936781_55936932	0.25	MTRNR2L3	MT-RNR2-like 3	1978	0.23
chr1_52083072_52083707	0.25	OSBPL9	oxysterol binding protein-like 9	608	0.77
chr2_198120374_198120867	0.25	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	46623	0.12
chr10_14879452_14879992	0.25	CDNF	cerebral dopamine neurotrophic factor	349	0.56
chr2_175854784_175854957	0.25	ENSG00000201425	.	12339	0.15
chr9_35646178_35646825	0.25	RP11-331F9.4		234	0.81
chr11_5711907_5712253	0.25	TRIM22	tripartite motif containing 22	177	0.91
chr7_91510205_91510446	0.25	MTERF	mitochondrial transcription termination factor	291	0.94
chr12_96529900_96530051	0.25	ENSG00000266889	.	33948	0.15
chr17_16472637_16472847	0.25	ZNF287	zinc finger protein 287	222	0.93
chr11_2468791_2468942	0.25	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	2645	0.21
chr18_47793998_47794618	0.25	CCDC11	coiled-coil domain containing 11	1416	0.36
chr15_80445342_80445551	0.25	FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)	207	0.95
chr11_77530634_77531102	0.25	RSF1	remodeling and spacing factor 1	884	0.42
chr5_68903659_68903865	0.24	RP11-848G14.2		10378	0.18
chr16_87498544_87498873	0.24	ZCCHC14	zinc finger, CCHC domain containing 14	26943	0.15
chr17_1686722_1687045	0.24	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	11870	0.11
chr14_50863724_50864050	0.24	CDKL1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	235	0.94
chr3_160281811_160282588	0.24	KPNA4	karyopherin alpha 4 (importin alpha 3)	1177	0.52
chr1_168329622_168329773	0.24	ENSG00000207974	.	15065	0.23
chr17_7464555_7465071	0.24	SENP3	SUMO1/sentrin/SMT3 specific peptidase 3	459	0.5
chr20_48294953_48295215	0.24	B4GALT5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	35331	0.15
chr7_112578777_112579037	0.24	C7orf60	chromosome 7 open reading frame 60	766	0.77
chr6_149637823_149638060	0.24	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	1122	0.52

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PROX1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.5	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.1	0.3	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.1	0.3	GO:0072033	renal vesicle formation(GO:0072033)
0.1	0.4	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.3	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.3	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	0.4	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.1	0.1	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.1	0.2	GO:1901798	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1	0.5	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.4	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1	0.4	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1	0.2	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.3	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.1	0.5	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.1	0.3	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.2	GO:2000189	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.1	0.2	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	0.3	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.2	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1	0.4	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.1	0.1	GO:0046931	pore complex assembly(GO:0046931)
0.1	0.2	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1	0.2	GO:0006591	ornithine metabolic process(GO:0006591)
0.1	0.2	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.1	0.2	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.1	0.2	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1	0.2	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	0.2	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.1	0.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.2	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.1	GO:0050942	regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636) regulation of pigment cell differentiation(GO:0050932) positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.2	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.4	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.2	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.2	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.3	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.2	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.2	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.2	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.2	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.2	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.2	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.8	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.2	GO:0000959	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.2	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.1	GO:0021610	cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.0	GO:0021561	facial nerve development(GO:0021561)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.2	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.2	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.2	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.1	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.2	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.3	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.1	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.2	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.4	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.0	GO:0031645	negative regulation of neurological system process(GO:0031645) negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.0	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.1	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.2	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.0	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0061756	leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0	0.2	GO:0051310	metaphase plate congression(GO:0051310)
0.0	0.1	GO:0016139	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.3	GO:0070206	protein trimerization(GO:0070206)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.2	GO:0048194	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.2	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.0	GO:0046321	positive regulation of fatty acid oxidation(GO:0046321)
0.0	0.0	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.0	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.0	GO:0006111	regulation of gluconeogenesis(GO:0006111)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.0	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.2	GO:0090181	regulation of cholesterol metabolic process(GO:0090181)
0.0	0.0	GO:1901984	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.0	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.4	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.2	GO:0043462	regulation of ATPase activity(GO:0043462)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.0	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0	0.1	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.3	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.0	0.2	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.2	GO:0006942	regulation of striated muscle contraction(GO:0006942)
0.0	0.0	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.2	GO:0048489	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0072698	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.2	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.2	GO:0001502	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.1	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.0	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.1	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.0	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.0	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701) regulation of gastric acid secretion(GO:0060453)
0.0	0.1	GO:0003341	cilium movement(GO:0003341)
0.0	0.1	GO:0030201	heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.0	GO:1901796	regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516) regulation of signal transduction by p53 class mediator(GO:1901796)
0.0	0.0	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.6	GO:0010827	regulation of glucose transport(GO:0010827)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.2	GO:0032570	response to progesterone(GO:0032570)
0.0	0.0	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.1	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.0	GO:0007549	dosage compensation(GO:0007549)
0.0	0.0	GO:0009414	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.0	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.0	GO:0052509	modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0	0.0	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0033483	gas homeostasis(GO:0033483)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.1	GO:0019682	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.4	GO:0042629	mast cell granule(GO:0042629)
0.1	0.4	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	0.3	GO:0010369	chromocenter(GO:0010369)
0.1	0.5	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	0.5	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.7	GO:0016235	aggresome(GO:0016235)
0.1	0.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.4	GO:0016342	catenin complex(GO:0016342)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.2	GO:0030904	retromer complex(GO:0030904)
0.0	0.3	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.4	GO:0008091	spectrin(GO:0008091)
0.0	0.5	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.2	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	1.0	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.4	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.0	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	1.0	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.3	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.0	GO:0043656	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.3	GO:0044438	microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0	0.5	GO:0005884	actin filament(GO:0005884)
0.0	0.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.4	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.0	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.5	GO:0031674	I band(GO:0031674)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.4	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.0	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.0	GO:0042405	nuclear inclusion body(GO:0042405)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.2	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.6	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.2	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1	0.2	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	0.3	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.1	0.3	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.1	0.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.3	GO:0048156	tau protein binding(GO:0048156)
0.1	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.2	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1	0.2	GO:0030911	TPR domain binding(GO:0030911)
0.1	0.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1	0.2	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.3	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.3	GO:0030507	spectrin binding(GO:0030507)
0.0	0.3	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.2	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.2	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.5	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.1	GO:0032357	single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.5	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0042805	actinin binding(GO:0042805)
0.0	0.3	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.3	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.0	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.5	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.0	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.3	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.6	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.5	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.2	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.6	GO:0005518	collagen binding(GO:0005518)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.5	GO:0005343	organic acid:sodium symporter activity(GO:0005343)
0.0	0.6	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.2	GO:0045296	cadherin binding(GO:0045296)
0.0	0.0	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.3	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.2	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.0	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.8	GO:0044389	ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0	0.2	GO:0017022	myosin binding(GO:0017022)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.0	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.0	GO:0002060	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	0.0	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.0	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.0	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0017069	snRNA binding(GO:0017069)
0.0	0.4	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.3	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.2	GO:0010181	FMN binding(GO:0010181)
0.0	0.0	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.0	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.4	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.0	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	1.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.0	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.2	GO:0016878	acid-thiol ligase activity(GO:0016878)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.7	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.2	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.3	PID BARD1 PATHWAY	BARD1 signaling events
0.7	PID BMP PATHWAY	BMP receptor signaling
0.2	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.5	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.3	PID INSULIN PATHWAY	Insulin Pathway
0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.4	PID TNF PATHWAY	TNF receptor signaling pathway
0.3	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.3	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.8	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.1	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.6	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.8	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.0	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.0	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.0	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME ADAPTIVE IMMUNE SYSTEM	Genes involved in Adaptive Immune System
0.0	0.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.1	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane