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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PTF1A

Z-value: 1.71

Motif logo

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Transcription factors associated with PTF1A

Gene Symbol Gene ID Gene Info
ENSG00000168267.5 PTF1A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
PTF1Achr10_23483170_2348332119890.336661-0.599.5e-02Click!

Activity of the PTF1A motif across conditions

Conditions sorted by the z-value of the PTF1A motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_152080538_152081099 1.17 TCHH
trichohyalin
5738
0.15
chr1_56943511_56943702 0.89 ENSG00000223307
.
100516
0.08
chr1_14924992_14926197 0.86 KAZN
kazrin, periplakin interacting protein
381
0.93
chr10_114714851_114715858 0.86 RP11-57H14.2

3720
0.26
chr17_76879212_76879961 0.81 TIMP2
TIMP metallopeptidase inhibitor 2
9354
0.14
chr10_123900999_123901504 0.80 TACC2
transforming, acidic coiled-coil containing protein 2
15022
0.26
chr10_105408364_105408783 0.80 SH3PXD2A
SH3 and PX domains 2A
12889
0.17
chr5_121412982_121413537 0.74 LOX
lysyl oxidase
721
0.73
chr5_153990189_153990659 0.73 ENSG00000264760
.
14792
0.21
chr11_22214479_22215097 0.72 ANO5
anoctamin 5
66
0.98
chr2_37116896_37117561 0.69 ENSG00000252756
.
22590
0.18
chr3_106059964_106060303 0.68 ENSG00000200610
.
174611
0.04
chr4_140925773_140926068 0.68 MAML3
mastermind-like 3 (Drosophila)
113799
0.06
chr19_41726536_41726687 0.68 CTD-2195B23.3

1345
0.26
chr12_63545508_63545951 0.67 AVPR1A
arginine vasopressin receptor 1A
1007
0.7
chr12_125002282_125002834 0.67 NCOR2
nuclear receptor corepressor 2
282
0.95
chr5_400345_400580 0.66 AHRR
aryl-hydrocarbon receptor repressor
20573
0.14
chr19_41195138_41195302 0.66 NUMBL
numb homolog (Drosophila)-like
277
0.86
chr5_149867086_149867391 0.66 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
1381
0.42
chr6_16741612_16741995 0.65 RP1-151F17.1

19566
0.23
chr17_2310404_2311021 0.65 MNT
MAX network transcriptional repressor
6300
0.12
chr1_61668583_61669016 0.65 RP4-802A10.1

78394
0.11
chr12_13353569_13354032 0.64 EMP1
epithelial membrane protein 1
4080
0.3
chr16_69998972_69999655 0.63 CLEC18A
C-type lectin domain family 18, member A
13669
0.14
chr5_121411093_121411244 0.62 LOX
lysyl oxidase
2812
0.31
chrX_47881179_47881404 0.62 SPACA5
sperm acrosome associated 5
14097
0.14
chr13_23948361_23948651 0.62 SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
1176
0.64
chr1_205648469_205649627 0.62 SLC45A3
solute carrier family 45, member 3
539
0.74
chr9_25677269_25678110 0.61 TUSC1
tumor suppressor candidate 1
1167
0.68
chr5_15500636_15500842 0.61 FBXL7
F-box and leucine-rich repeat protein 7
434
0.91
chr2_27301899_27302732 0.59 EMILIN1
elastin microfibril interfacer 1
880
0.32
chr7_100424107_100424380 0.59 EPHB4
EPH receptor B4
494
0.66
chr12_20522500_20522819 0.58 PDE3A
phosphodiesterase 3A, cGMP-inhibited
480
0.52
chr8_25042452_25043634 0.58 DOCK5
dedicator of cytokinesis 5
663
0.75
chr9_118917055_118917469 0.58 PAPPA
pregnancy-associated plasma protein A, pappalysin 1
1179
0.59
chr21_17566581_17566826 0.57 ENSG00000201025
.
90386
0.1
chr18_57364074_57364448 0.56 CCBE1
collagen and calcium binding EGF domains 1
351
0.64
chr18_32172945_32173175 0.56 DTNA
dystrobrevin, alpha
222
0.97
chr11_113061246_113061662 0.56 NCAM1
neural cell adhesion molecule 1
6461
0.26
chr14_23307170_23307406 0.55 MMP14
matrix metallopeptidase 14 (membrane-inserted)
767
0.41
chr12_10871040_10871278 0.55 YBX3
Y box binding protein 3
4747
0.2
chr16_3162631_3163041 0.54 ZNF205
zinc finger protein 205
40
0.8
chr7_121776912_121777110 0.54 AASS
aminoadipate-semialdehyde synthase
3135
0.34
chr9_89952337_89952906 0.53 ENSG00000212421
.
77256
0.11
chr15_90357053_90357234 0.53 ANPEP
alanyl (membrane) aminopeptidase
951
0.46
chr9_113341179_113342041 0.53 SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
213
0.96
chr1_215180647_215181021 0.53 KCNK2
potassium channel, subfamily K, member 2
1636
0.56
chr21_30714711_30715089 0.52 BACH1-IT1
BACH1 intronic transcript 1 (non-protein coding)
9055
0.17
chr11_85396326_85396540 0.52 CCDC89
coiled-coil domain containing 89
887
0.51
chr15_33011706_33011883 0.52 GREM1
gremlin 1, DAN family BMP antagonist
1589
0.4
chr3_57529834_57530279 0.52 DNAH12
dynein, axonemal, heavy chain 12
12
0.96
chr4_138045655_138046009 0.52 ENSG00000222526
.
103450
0.09
chr2_162275011_162275548 0.51 TBR1
T-box, brain, 1
873
0.56
chr10_81058972_81059213 0.51 ZMIZ1
zinc finger, MIZ-type containing 1
6883
0.25
chr5_172754207_172754714 0.50 STC2
stanniocalcin 2
596
0.75
chr1_209823926_209824302 0.50 LAMB3
laminin, beta 3
565
0.7
chr11_111606115_111606547 0.50 PPP2R1B
protein phosphatase 2, regulatory subunit A, beta
19431
0.17
chr7_95107815_95108198 0.49 ASB4
ankyrin repeat and SOCS box containing 4
7207
0.2
chr6_163681477_163682017 0.49 ENSG00000239136
.
33805
0.21
chr10_72973576_72973936 0.49 UNC5B
unc-5 homolog B (C. elegans)
1072
0.43
chr13_80912572_80913077 0.49 SPRY2
sprouty homolog 2 (Drosophila)
970
0.67
chr2_241519242_241519542 0.49 RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
4473
0.13
chr4_22517802_22518220 0.49 GPR125
G protein-coupled receptor 125
334
0.94
chr15_64231749_64232239 0.49 RP11-111E14.1

11521
0.22
chr1_8523343_8523612 0.49 RP5-1115A15.1

37779
0.14
chr3_61548960_61549133 0.49 PTPRG
protein tyrosine phosphatase, receptor type, G
1461
0.59
chr15_66999211_66999494 0.48 SMAD6
SMAD family member 6
1578
0.48
chr10_3087908_3088170 0.47 PFKP
phosphofructokinase, platelet
20486
0.26
chr3_87007555_87007776 0.47 VGLL3
vestigial like 3 (Drosophila)
32187
0.25
chr12_56100408_56100559 0.46 ITGA7
integrin, alpha 7
1002
0.31
chr16_70221940_70222878 0.46 CLEC18C
C-type lectin domain family 18, member C
14349
0.1
chr3_98605225_98605614 0.46 DCBLD2
discoidin, CUB and LCCL domain containing 2
14596
0.17
chr7_152219742_152220164 0.46 ENSG00000199404
.
70223
0.09
chr7_65742141_65742476 0.46 TPST1
tyrosylprotein sulfotransferase 1
55717
0.12
chr4_81157116_81157324 0.46 FGF5
fibroblast growth factor 5
30533
0.17
chr10_94958545_94959442 0.46 CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
125346
0.05
chr1_156659032_156659371 0.46 NES
nestin
12012
0.08
chr3_64253622_64253921 0.45 PRICKLE2
prickle homolog 2 (Drosophila)
116
0.98
chr1_1676260_1677404 0.45 SLC35E2
solute carrier family 35, member E2
526
0.68
chr14_24838154_24838623 0.45 NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
15
0.95
chr10_830968_831170 0.45 LARP4B
La ribonucleoprotein domain family, member 4B
32717
0.18
chr2_109210392_109210708 0.45 LIMS1
LIM and senescent cell antigen-like domains 1
5628
0.26
chr8_58660710_58660861 0.45 ENSG00000252057
.
191641
0.03
chr3_127540841_127541975 0.45 MGLL
monoglyceride lipase
214
0.96
chr10_21625398_21625641 0.45 ENSG00000207264
.
14629
0.25
chr16_74440490_74441404 0.44 CLEC18B
C-type lectin domain family 18, member B
14343
0.14
chr9_110253387_110253828 0.44 KLF4
Kruppel-like factor 4 (gut)
844
0.66
chr5_163723747_163723929 0.44 CTC-340A15.2

86
0.99
chr11_129183232_129183395 0.44 ARHGAP32
Rho GTPase activating protein 32
34094
0.2
chr2_9815742_9816384 0.44 YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
44920
0.13
chr10_990422_990912 0.44 RP11-363N22.2

11701
0.15
chr1_68214173_68214559 0.44 ENSG00000238778
.
23970
0.19
chr4_159042061_159042299 0.43 FAM198B
family with sequence similarity 198, member B
38653
0.16
chr18_53446598_53447540 0.43 TCF4
transcription factor 4
115051
0.07
chr12_22094270_22094690 0.43 ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
144
0.97
chr6_53934757_53935103 0.43 MLIP-AS1
MLIP antisense RNA 1
9594
0.22
chr6_76645073_76645368 0.43 IMPG1
interphotoreceptor matrix proteoglycan 1
454
0.81
chr7_80548112_80548336 0.43 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
275
0.96
chr2_238111061_238111273 0.43 AC112715.2
Uncharacterized protein
54567
0.14
chr3_133613529_133613925 0.43 RAB6B
RAB6B, member RAS oncogene family
164
0.96
chr4_186456818_186456988 0.43 PDLIM3
PDZ and LIM domain 3
137
0.96
chr1_87239567_87240110 0.43 SH3GLB1
SH3-domain GRB2-like endophilin B1
69260
0.09
chr2_220777171_220777508 0.42 ENSG00000266518
.
6053
0.3
chr11_1769744_1769994 0.42 IFITM10
interferon induced transmembrane protein 10
1952
0.17
chr2_25121479_25121715 0.42 ADCY3
adenylate cyclase 3
20701
0.17
chr11_89867867_89868379 0.42 NAALAD2
N-acetylated alpha-linked acidic dipeptidase 2
109
0.97
chr11_503866_504897 0.42 RNH1
ribonuclease/angiogenin inhibitor 1
171
0.89
chr12_91575190_91575391 0.42 DCN
decorin
537
0.85
chr11_118779768_118779967 0.42 ENSG00000264211
.
1550
0.19
chr3_32619082_32619439 0.41 DYNC1LI1
dynein, cytoplasmic 1, light intermediate chain 1
6894
0.25
chr12_3069053_3070004 0.41 TEAD4
TEA domain family member 4
445
0.77
chr3_125985987_125986785 0.41 ALDH1L1-AS2
ALDH1L1 antisense RNA 2
60288
0.1
chr2_167395803_167395954 0.41 SCN7A
sodium channel, voltage-gated, type VII, alpha subunit
45121
0.2
chr8_122652196_122652655 0.41 HAS2-AS1
HAS2 antisense RNA 1
283
0.88
chr17_27043546_27044298 0.41 RAB34
RAB34, member RAS oncogene family
844
0.24
chr8_101635798_101636113 0.41 KB-1083B1.1

5145
0.18
chr7_151123543_151123787 0.41 RP4-555L14.4

1104
0.36
chr8_101522522_101522795 0.41 KB-1615E4.3

17902
0.16
chr11_123064762_123065022 0.41 CLMP
CXADR-like membrane protein
1097
0.52
chr17_76880061_76880570 0.41 TIMP2
TIMP metallopeptidase inhibitor 2
10083
0.14
chr16_49677980_49678248 0.41 ZNF423
zinc finger protein 423
3351
0.32
chr8_105600205_105600588 0.41 LRP12
low density lipoprotein receptor-related protein 12
838
0.62
chr3_64673863_64674037 0.40 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
274
0.92
chr1_152081115_152081371 0.40 TCHH
trichohyalin
5313
0.15
chr7_95225262_95225474 0.40 PDK4
pyruvate dehydrogenase kinase, isozyme 4
435
0.6
chr6_27173563_27173801 0.40 PRSS16
protease, serine, 16 (thymus)
41798
0.1
chr4_177713602_177713811 0.40 VEGFC
vascular endothelial growth factor C
175
0.97
chr21_44499975_44500459 0.40 CBS
cystathionine-beta-synthase
3164
0.22
chr6_150246697_150247451 0.40 RAET1G
retinoic acid early transcript 1G
2817
0.17
chr5_59783926_59784223 0.40 PDE4D
phosphodiesterase 4D, cAMP-specific
171
0.97
chr1_147781215_147781516 0.39 ENSG00000252744
.
21031
0.14
chr12_52627039_52627830 0.39 KRT7
keratin 7
536
0.63
chr10_52751128_52751393 0.39 PRKG1
protein kinase, cGMP-dependent, type I
142
0.97
chr7_137671468_137671947 0.39 CREB3L2
cAMP responsive element binding protein 3-like 2
15086
0.19
chr20_48602538_48602821 0.39 SNAI1
snail family zinc finger 1
3143
0.21
chr6_15505544_15505788 0.39 DTNBP1
dystrobrevin binding protein 1
42927
0.19
chr17_59474132_59474398 0.39 RP11-332H18.4

1457
0.28
chr11_19736431_19736825 0.39 NAV2
neuron navigator 2
1485
0.49
chr7_75921090_75921672 0.39 ENSG00000263569
.
3273
0.2
chr7_101579659_101580126 0.39 CTB-181H17.1

23504
0.22
chr2_230133986_230134183 0.39 PID1
phosphotyrosine interaction domain containing 1
1897
0.44
chr12_16500618_16501134 0.39 MGST1
microsomal glutathione S-transferase 1
145
0.97
chr3_106954974_106955246 0.39 ENSG00000220989
.
128919
0.06
chr7_41740779_41741576 0.39 INHBA
inhibin, beta A
970
0.56
chr8_123625355_123625506 0.38 ENSG00000238901
.
58100
0.15
chr3_141379125_141379497 0.38 RNF7
ring finger protein 7
77735
0.09
chr21_37304382_37305022 0.38 FKSG68

33975
0.16
chr3_16216188_16216711 0.38 GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
233
0.95
chr5_123121441_123121770 0.38 CSNK1G3
casein kinase 1, gamma 3
197486
0.03
chr9_131486459_131486739 0.38 RP11-545E17.3

125
0.59
chr1_245461989_245462162 0.38 RP11-62I21.1

64272
0.12
chr10_13924116_13924710 0.38 FRMD4A
FERM domain containing 4A
23501
0.22
chr6_146864295_146864606 0.38 RAB32
RAB32, member RAS oncogene family
379
0.91
chr1_79306379_79306727 0.38 ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
77017
0.11
chr11_44054106_44054508 0.38 ACCSL
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like
15224
0.17
chr5_34657573_34657939 0.37 CTD-2024P10.1

401
0.72
chr20_17917274_17917458 0.37 ENSG00000212232
.
26223
0.13
chr11_65260025_65260256 0.37 SCYL1
SCY1-like 1 (S. cerevisiae)
32408
0.08
chr11_94473290_94474384 0.37 RP11-867G2.8

316
0.92
chr11_12309017_12309498 0.37 MICALCL
MICAL C-terminal like
810
0.62
chr12_108699646_108700021 0.37 CMKLR1
chemokine-like receptor 1
11861
0.27
chr4_81951926_81952331 0.37 BMP3
bone morphogenetic protein 3
9
0.99
chr12_46759532_46760006 0.37 SLC38A2
solute carrier family 38, member 2
679
0.75
chr11_27739578_27739815 0.37 BDNF
brain-derived neurotrophic factor
1598
0.49
chr12_95779577_95779767 0.37 RP11-167N24.6
Uncharacterized protein
5000
0.22
chr5_77943226_77943942 0.37 LHFPL2
lipoma HMGIC fusion partner-like 2
1064
0.69
chr2_74875258_74875460 0.37 M1AP
meiosis 1 associated protein
98
0.96
chr19_44860491_44860902 0.37 ZNF112
zinc finger protein 112
130
0.96
chr1_159111648_159111897 0.37 AIM2
absent in melanoma 2
1474
0.37
chr8_8175034_8175211 0.37 SGK223
Tyrosine-protein kinase SgK223
64135
0.1
chr18_74331565_74332218 0.37 LINC00908
long intergenic non-protein coding RNA 908
91017
0.08
chr10_102759781_102760726 0.37 LZTS2
leucine zipper, putative tumor suppressor 2
643
0.52
chr1_153584096_153584410 0.36 S100A16
S100 calcium binding protein A16
1306
0.22
chr2_98765349_98765752 0.36 VWA3B
von Willebrand factor A domain containing 3B
61851
0.13
chr20_49347136_49348386 0.36 PARD6B
par-6 family cell polarity regulator beta
320
0.89
chr5_39399204_39399669 0.36 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
4934
0.29
chr7_128171824_128173030 0.36 RP11-274B21.1

1279
0.43
chr11_121593168_121593875 0.36 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
132393
0.05
chr8_126354311_126354524 0.36 RP11-550A5.2

9241
0.25
chr2_217234156_217234543 0.36 MARCH4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
2401
0.25
chr5_32505591_32505798 0.36 SUB1
SUB1 homolog (S. cerevisiae)
26045
0.2
chr4_148402515_148403207 0.36 EDNRA
endothelin receptor type A
777
0.76
chr4_175041496_175041671 0.36 FBXO8
F-box protein 8
163231
0.04
chr5_113390839_113391098 0.36 ENSG00000222706
.
198242
0.03
chr11_47431074_47431348 0.36 SLC39A13
solute carrier family 39 (zinc transporter), member 13
69
0.85
chr11_132813237_132813595 0.36 OPCML
opioid binding protein/cell adhesion molecule-like
150
0.98
chr8_20060548_20060978 0.36 ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
5813
0.2
chr1_44287968_44288172 0.36 ST3GAL3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
77190
0.07
chr10_39023998_39024149 0.35 LINC00999
long intergenic non-protein coding RNA 999
306999
0.01
chr15_96878049_96878255 0.35 ENSG00000222651
.
1662
0.27
chr6_1596418_1596605 0.35 FOXC1
forkhead box C1
14170
0.28
chr15_37175433_37176047 0.35 ENSG00000212511
.
30899
0.23
chr22_50698815_50699396 0.35 MAPK12
mitogen-activated protein kinase 12
632
0.49
chr20_33759810_33760395 0.35 PROCR
protein C receptor, endothelial
226
0.9
chr5_158521759_158522243 0.35 EBF1
early B-cell factor 1
4700
0.29
chr21_17680198_17680437 0.35 ENSG00000201025
.
23228
0.27
chr10_21688030_21688514 0.35 ENSG00000207264
.
77382
0.08
chr18_77245045_77245203 0.35 AC018445.1
Uncharacterized protein
30933
0.21
chr19_2962281_2962480 0.35 TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
15064
0.12
chr2_219646650_219647418 0.35 CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
555
0.7

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PTF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 0.9 GO:0060437 lung growth(GO:0060437)
0.2 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 0.4 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.2 0.8 GO:0060841 venous blood vessel development(GO:0060841)
0.2 0.4 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.2 0.3 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.2 0.5 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2 0.7 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.2 0.7 GO:0060068 vagina development(GO:0060068)
0.2 0.5 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.2 0.5 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.2 0.5 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.2 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2 0.3 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.7 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.1 GO:0060430 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.1 0.4 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.3 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.4 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.5 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.2 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.1 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.4 GO:0010107 potassium ion import(GO:0010107)
0.1 0.9 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.5 GO:0036303 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1 0.4 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 0.3 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.3 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 0.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.3 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.3 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.1 0.2 GO:0060677 ureteric bud elongation(GO:0060677)
0.1 0.1 GO:0003161 cardiac conduction system development(GO:0003161)
0.1 0.1 GO:0060976 coronary vasculature development(GO:0060976)
0.1 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.2 GO:0050955 thermoception(GO:0050955)
0.1 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.2 GO:2000095 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.2 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1 0.2 GO:0085029 extracellular matrix assembly(GO:0085029)
0.1 0.2 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.4 GO:0060039 pericardium development(GO:0060039)
0.1 0.2 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.3 GO:0014824 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1 0.4 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.1 0.1 GO:0042637 catagen(GO:0042637)
0.1 0.2 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.5 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.2 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.3 GO:0003309 type B pancreatic cell differentiation(GO:0003309)
0.1 0.1 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.1 0.1 GO:0010996 response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.1 0.2 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1 0.3 GO:0070230 positive regulation of lymphocyte apoptotic process(GO:0070230) positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.2 GO:0021794 thalamus development(GO:0021794)
0.1 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.1 0.2 GO:0060687 regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.1 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.1 GO:0060242 contact inhibition(GO:0060242)
0.1 0.2 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1 0.2 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.2 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 1.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0071320 cellular response to cAMP(GO:0071320)
0.0 0.3 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:0014821 phasic smooth muscle contraction(GO:0014821)
0.0 0.1 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.3 GO:0008347 glial cell migration(GO:0008347)
0.0 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0021892 cerebral cortex GABAergic interneuron differentiation(GO:0021892)
0.0 0.4 GO:0071456 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.3 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0022601 menstrual cycle phase(GO:0022601)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0043954 cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.4 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.3 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.2 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.0 0.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.3 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0050951 sensory perception of temperature stimulus(GO:0050951) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0048293 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.3 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 1.4 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.0 GO:0070091 glucagon secretion(GO:0070091)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:0090232 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 1.3 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.2 GO:0001660 fever generation(GO:0001660)
0.0 0.0 GO:0016241 regulation of macroautophagy(GO:0016241)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0051818 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.5 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
0.0 0.1 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.1 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.2 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.3 GO:0048566 embryonic digestive tract development(GO:0048566)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0001743 optic placode formation(GO:0001743)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.0 0.1 GO:0050922 negative regulation of chemotaxis(GO:0050922)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0010460 positive regulation of heart rate(GO:0010460)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.1 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.0 GO:0003157 endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.1 GO:0032026 response to magnesium ion(GO:0032026)
0.0 0.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:1901655 cellular response to ketone(GO:1901655)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0 0.0 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.0 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.1 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0055094 response to lipoprotein particle(GO:0055094)
0.0 0.0 GO:0014808 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.0 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.0 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.1 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.6 GO:0016358 dendrite development(GO:0016358)
0.0 0.2 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.2 GO:0021766 hippocampus development(GO:0021766)
0.0 0.0 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0071675 mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.0 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.0 GO:0003207 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.1 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.0 GO:0048820 hair cycle phase(GO:0044851) hair follicle maturation(GO:0048820)
0.0 0.0 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.0 0.1 GO:0010224 response to UV-B(GO:0010224)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.3 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0021779 oligodendrocyte cell fate commitment(GO:0021779)
0.0 0.0 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.1 GO:0007215 glutamate receptor signaling pathway(GO:0007215)
0.0 0.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0008595 blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.0 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.0 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.0 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.0 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:1903318 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.1 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0021543 pallium development(GO:0021543)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.0 GO:0021889 olfactory bulb interneuron differentiation(GO:0021889)
0.0 0.2 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0015810 C4-dicarboxylate transport(GO:0015740) aspartate transport(GO:0015810)
0.0 0.1 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.1 GO:0019430 removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.0 GO:0031054 pre-miRNA processing(GO:0031054)
0.0 0.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:0006907 pinocytosis(GO:0006907)
0.0 0.0 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0042748 circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188) positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.0 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.0 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:2000192 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.0 GO:0043302 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.0 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.0 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.3 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0070852 cell body fiber(GO:0070852)
0.2 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 0.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.5 GO:0001527 microfibril(GO:0001527)
0.1 0.8 GO:0030315 T-tubule(GO:0030315)
0.1 0.4 GO:0071437 invadopodium(GO:0071437)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0043256 laminin complex(GO:0043256)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0030673 axolemma(GO:0030673)
0.1 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.4 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.3 GO:0010369 chromocenter(GO:0010369)
0.1 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0032589 neuron projection membrane(GO:0032589)
0.0 2.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0033643 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 4.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0030286 dynein complex(GO:0030286)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0 0.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0060198 clathrin-sculpted vesicle(GO:0060198)
0.0 0.9 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 2.0 GO:0005912 adherens junction(GO:0005912)
0.0 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.3 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.0 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.2 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.5 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.5 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.3 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.8 GO:0070628 proteasome binding(GO:0070628)
0.1 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.2 GO:0045545 syndecan binding(GO:0045545)
0.1 0.2 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1 0.2 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.7 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.8 GO:0030553 cGMP binding(GO:0030553)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0004470 malic enzyme activity(GO:0004470)
0.1 0.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.2 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 1.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 2.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0001077 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.0 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.0 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.2 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0035240 dopamine binding(GO:0035240)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.0 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.0 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.7 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.0 GO:0001515 opioid peptide activity(GO:0001515)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 6.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 5.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID IGF1 PATHWAY IGF1 pathway
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.1 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.8 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC