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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for RARB

Z-value: 1.32

Motif logo

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Transcription factors associated with RARB

Gene Symbol Gene ID Gene Info
RARB
ENSG00000077092.14 retinoic acid receptor beta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr3_25496127_25496278RARB35990.335449-0.891.2e-03Click!
chr3_25497685_25497836RARB20410.437538-0.863.1e-03Click!
chr3_25469781_25469984RARB800.983222-0.863.2e-03Click!
chr3_25465504_25465718RARB41430.319253-0.863.3e-03Click!
chr3_25495752_25495903RARB39740.324844-0.853.9e-03Click!

Activity of the RARB motif across conditions

Conditions sorted by the z-value of the RARB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_98334070_98334346 0.86 ZAP70
 zeta-chain (TCR) associated protein kinase 70kDa
 4185
 0.2
chr14_22961374_22961769 0.84 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 5400
 0.11
chr2_173327465_173327877 0.82 AC078883.3
3069
 0.24
chrX_70330282_70330478 0.81 IL2RG
 interleukin 2 receptor, gamma
 368
 0.76
chr6_143189309_143189460 0.77 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 31200
 0.22
chr6_152504718_152504928 0.73 SYNE1
 spectrin repeat containing, nuclear envelope 1
 15324
 0.29
chr3_183273082_183273407 0.73 KLHL6
 kelch-like family member 6
 233
 0.92
chr14_22950797_22950948 0.72 TRAJ55
 T cell receptor alpha joining 55 (pseudogene)
 186
 0.79
chr17_76127167_76127361 0.71 TMC8
 transmembrane channel-like 8
 395
 0.51
chr13_52397765_52397916 0.68 RP11-327P2.5
19407
 0.17
chrX_11780001_11780185 0.66 MSL3
 male-specific lethal 3 homolog (Drosophila)
 2346
 0.44
chr6_128221812_128222507 0.66 THEMIS
 thymocyte selection associated
 56
 0.99
chr3_16329814_16329965 0.65 OXNAD1
 oxidoreductase NAD-binding domain containing 1
 19141
 0.15
chr2_120687736_120687954 0.65 PTPN4
 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
 493
 0.83
chr14_22949623_22949774 0.64 ENSG00000251002
 .
 580
 0.49
chr9_139990412_139990681 0.64 ENSG00000199411
 .
 1749
 0.12
chr17_59981888_59982128 0.63 INTS2
 integrator complex subunit 2
 22779
 0.17
chr19_23984835_23985137 0.63 RP11-255H23.2
11412
 0.19
chr3_196368779_196369009 0.62 PIGX
 phosphatidylinositol glycan anchor biosynthesis, class X
 2248
 0.2
chr10_73843197_73843461 0.60 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 4757
 0.26
chrX_48772131_48772362 0.60 PIM2
 pim-2 oncogene
 766
 0.45
chr22_37680309_37680627 0.59 CYTH4
 cytohesin 4
 1940
 0.3
chrX_78202204_78202379 0.58 P2RY10
 purinergic receptor P2Y, G-protein coupled, 10
 1373
 0.61
chr2_175460517_175460758 0.58 WIPF1
 WAS/WASL interacting protein family, member 1
 1856
 0.33
chr3_121378552_121379115 0.58 HCLS1
 hematopoietic cell-specific Lyn substrate 1
 912
 0.5
chr21_15917471_15917848 0.58 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
 1003
 0.63
chr1_151129872_151130112 0.58 SCNM1
 sodium channel modifier 1
 852
 0.29
chr22_39639623_39639926 0.55 PDGFB
 platelet-derived growth factor beta polypeptide
 753
 0.58
chr13_99959249_99959863 0.55 GPR183
 G protein-coupled receptor 183
 103
 0.97
chr6_90788160_90788311 0.54 ENSG00000222078
 .
 77010
 0.1
chr19_42061527_42061721 0.54 CEACAM21
 carcinoembryonic antigen-related cell adhesion molecule 21
 5738
 0.18
chrX_78406189_78406340 0.54 GPR174
 G protein-coupled receptor 174
 20205
 0.29
chr4_40202563_40202865 0.53 RHOH
 ras homolog family member H
 750
 0.7
chr5_130881605_130881983 0.53 RAPGEF6
 Rap guanine nucleotide exchange factor (GEF) 6
 13068
 0.29
chr7_138779169_138779413 0.53 ZC3HAV1
 zinc finger CCCH-type, antiviral 1
 14809
 0.2
chr13_75890123_75890274 0.53 TBC1D4
 TBC1 domain family, member 4
 25469
 0.22
chr8_8727283_8727434 0.52 MFHAS1
 malignant fibrous histiocytoma amplified sequence 1
 23797
 0.18
chr10_14606149_14606418 0.52 FAM107B
 family with sequence similarity 107, member B
 7746
 0.26
chr2_87830138_87830289 0.52 RP11-1399P15.1
52660
 0.16
chr11_128387865_128388196 0.51 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 4066
 0.27
chr7_138778953_138779104 0.50 ZC3HAV1
 zinc finger CCCH-type, antiviral 1
 15015
 0.2
chr2_120988902_120989053 0.50 TMEM185B
 transmembrane protein 185B
 7993
 0.17
chr5_130849992_130850161 0.50 RAPGEF6
 Rap guanine nucleotide exchange factor (GEF) 6
 6226
 0.32
chr3_107844575_107844939 0.50 CD47
 CD47 molecule
 34885
 0.22
chr18_56105832_56106078 0.49 ENSG00000207778
 .
 12351
 0.17
chr2_112177530_112177803 0.49 ENSG00000266139
 .
 98998
 0.09
chr19_10449910_10450285 0.48 ICAM3
 intercellular adhesion molecule 3
 198
 0.86
chr3_109525427_109525578 0.47 ENSG00000265956
 .
 203827
 0.03
chr16_27414444_27414647 0.47 IL21R
 interleukin 21 receptor
 122
 0.97
chr2_213976639_213976790 0.47 IKZF2
 IKAROS family zinc finger 2 (Helios)
 36639
 0.21
chr5_156611761_156611912 0.47 ITK
 IL2-inducible T-cell kinase
 3999
 0.16
chr5_79484995_79485498 0.47 ENSG00000239159
 .
 50162
 0.12
chr14_22996017_22996172 0.47 TRAJ15
 T cell receptor alpha joining 15
 2486
 0.17
chr1_32718292_32718517 0.46 LCK
 lymphocyte-specific protein tyrosine kinase
 1529
 0.2
chr12_123560353_123560523 0.46 PITPNM2
 phosphatidylinositol transfer protein, membrane-associated 2
 204
 0.94
chr3_152000711_152000862 0.45 MBNL1-AS1
 MBNL1 antisense RNA 1
 13442
 0.21
chr6_15340960_15341111 0.45 ENSG00000201519
 .
 16332
 0.2
chrX_153361307_153361458 0.44 MECP2
 methyl CpG binding protein 2 (Rett syndrome)
 1054
 0.45
chr12_22485870_22486021 0.44 ST8SIA1
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
 1152
 0.64
chr6_154567141_154567292 0.44 IPCEF1
 interaction protein for cytohesin exchange factors 1
 774
 0.79
chr15_26095881_26096079 0.43 ENSG00000266517
 .
 2008
 0.32
chrX_78417451_78417673 0.43 GPR174
 G protein-coupled receptor 174
 8907
 0.32
chr9_138981896_138982047 0.43 NACC2
 NACC family member 2, BEN and BTB (POZ) domain containing
 5160
 0.22
chr20_62199083_62199345 0.43 HELZ2
 helicase with zinc finger 2, transcriptional coactivator
 213
 0.88
chr13_74807358_74807666 0.43 ENSG00000206617
 .
 55839
 0.16
chr17_10603321_10603720 0.43 ADPRM
 ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
 2609
 0.18
chr1_154300198_154300512 0.42 ATP8B2
 ATPase, aminophospholipid transporter, class I, type 8B, member 2
 79
 0.94
chr11_122722660_122722811 0.42 CRTAM
 cytotoxic and regulatory T cell molecule
 10276
 0.21
chr1_39684129_39684368 0.42 RP11-416A14.1
12064
 0.17
chr5_40515444_40515595 0.42 ENSG00000199552
 .
 139546
 0.05
chr14_99735608_99735969 0.42 BCL11B
 B-cell CLL/lymphoma 11B (zinc finger protein)
 1777
 0.38
chr3_195267203_195267354 0.41 PPP1R2
 protein phosphatase 1, regulatory (inhibitor) subunit 2
 2898
 0.21
chr1_198632029_198632471 0.41 RP11-553K8.5
3940
 0.29
chr11_128379892_128380047 0.41 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 4680
 0.27
chr2_225265820_225265971 0.41 FAM124B
 family with sequence similarity 124B
 816
 0.76
chr2_227703538_227703689 0.41 RHBDD1
 rhomboid domain containing 1
 1349
 0.49
chr2_231090336_231091061 0.40 SP140
 SP140 nuclear body protein
 219
 0.54
chr2_201331503_201331739 0.40 SPATS2L
 spermatogenesis associated, serine-rich 2-like
 26249
 0.16
chr8_21769513_21769765 0.40 DOK2
 docking protein 2, 56kDa
 1535
 0.4
chr5_14676474_14676736 0.40 FAM105B
 family with sequence similarity 105, member B
 5054
 0.24
chr13_79967234_79967432 0.40 ENSG00000252496
 .
 3567
 0.23
chr1_156785458_156785677 0.39 NTRK1
 neurotrophic tyrosine kinase, receptor, type 1
 119
 0.91
chr7_123603687_123603838 0.39 SPAM1
 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
 16008
 0.19
chr17_66196156_66196600 0.39 AMZ2
 archaelysin family metallopeptidase 2
 47337
 0.11
chr12_3861008_3861159 0.39 EFCAB4B
 EF-hand calcium binding domain 4B
 1180
 0.56
chr10_70444201_70444500 0.39 RP11-119F7.5
13907
 0.15
chr2_109237700_109238010 0.39 LIMS1
 LIM and senescent cell antigen-like domains 1
 133
 0.97
chr3_128507459_128507964 0.39 ENSG00000244232
 .
 3721
 0.22
chr16_87241773_87241924 0.39 RP11-899L11.3
7673
 0.23
chr6_11852612_11852763 0.39 ADTRP
 androgen-dependent TFPI-regulating protein
 45408
 0.18
chr17_4618141_4618477 0.39 ARRB2
 arrestin, beta 2
 575
 0.53
chr1_158978812_158979065 0.38 IFI16
 interferon, gamma-inducible protein 16
 153
 0.96
chr2_99386487_99386649 0.38 ENSG00000201070
 .
 12305
 0.21
chr15_63483779_63483976 0.38 RAB8B
 RAB8B, member RAS oncogene family
 2072
 0.34
chr2_143886988_143887259 0.38 ARHGAP15
 Rho GTPase activating protein 15
 240
 0.95
chr7_87318553_87318704 0.38 ABCB1
 ATP-binding cassette, sub-family B (MDR/TAP), member 1
 23936
 0.21
chr4_90224526_90224677 0.38 GPRIN3
 GPRIN family member 3
 4560
 0.34
chr15_61012992_61013143 0.38 ENSG00000212625
 .
 15901
 0.2
chr12_15112961_15113206 0.38 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
 1117
 0.46
chr2_212476372_212476523 0.38 ENSG00000199585
 .
 76069
 0.13
chr15_81584764_81585010 0.37 IL16
 interleukin 16
 4367
 0.24
chr1_12533236_12533387 0.37 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 5293
 0.24
chr14_99710942_99711195 0.37 AL109767.1
18217
 0.2
chr7_104584232_104584453 0.37 ENSG00000251911
 .
 27392
 0.16
chr21_46332173_46332515 0.37 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 969
 0.4
chr1_9882638_9884014 0.37 CLSTN1
 calsyntenin 1
 716
 0.65
chr19_50002038_50002189 0.36 ENSG00000200530
 .
 1136
 0.16
chr19_50062782_50062933 0.36 NOSIP
 nitric oxide synthase interacting protein
 1030
 0.27
chr5_141467902_141468053 0.36 NDFIP1
 Nedd4 family interacting protein 1
 20093
 0.2
chr1_160547631_160547822 0.36 CD84
 CD84 molecule
 1537
 0.33
chr21_30204306_30204701 0.36 N6AMT1
 N-6 adenine-specific DNA methyltransferase 1 (putative)
 53190
 0.14
chr19_18414393_18414628 0.36 LSM4
 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
 12559
 0.09
chr14_100534053_100534268 0.36 EVL
 Enah/Vasp-like
 1386
 0.36
chr1_12230241_12230523 0.36 TNFRSF1B
 tumor necrosis factor receptor superfamily, member 1B
 3322
 0.2
chr3_71351252_71351403 0.35 FOXP1
 forkhead box P1
 2584
 0.35
chr1_100866151_100866481 0.35 ENSG00000216067
 .
 21985
 0.18
chr9_36485594_36485745 0.35 RNF38
 ring finger protein 38
 84474
 0.09
chrX_40430227_40430433 0.35 ATP6AP2
 ATPase, H+ transporting, lysosomal accessory protein 2
 9816
 0.21
chr11_14722182_14722400 0.35 PDE3B
 phosphodiesterase 3B, cGMP-inhibited
 56914
 0.14
chr14_22947593_22947744 0.35 TRAJ60
 T cell receptor alpha joining 60 (pseudogene)
 2372
 0.15
chr2_106392629_106392859 0.35 NCK2
 NCK adaptor protein 2
 30556
 0.23
chr17_56404642_56404793 0.35 BZRAP1
 benzodiazepine receptor (peripheral) associated protein 1
 728
 0.47
chr7_92744983_92745334 0.35 SAMD9
 sterile alpha motif domain containing 9
 2117
 0.37
chr1_207088744_207089040 0.35 FAIM3
 Fas apoptotic inhibitory molecule 3
 6320
 0.15
chr6_128214596_128214747 0.35 THEMIS
 thymocyte selection associated
 7432
 0.31
chr9_117353596_117353986 0.34 ATP6V1G1
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
 3765
 0.18
chr1_160635203_160635434 0.34 RP11-404F10.2
5250
 0.17
chr13_46753268_46753419 0.34 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 3116
 0.21
chr7_26704596_26704975 0.34 C7orf71
 chromosome 7 open reading frame 71
 27295
 0.23
chr22_44391651_44392034 0.34 PARVB
 parvin, beta
 3249
 0.27
chr19_16482178_16482409 0.34 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 9529
 0.15
chr1_24832184_24832335 0.34 RCAN3
 RCAN family member 3
 1798
 0.32
chr6_36171723_36172059 0.34 BRPF3
 bromodomain and PHD finger containing, 3
 300
 0.89
chr14_32672059_32672251 0.33 ENSG00000202337
 .
 320
 0.8
chr14_99737865_99738043 0.33 BCL11B
 B-cell CLL/lymphoma 11B (zinc finger protein)
 93
 0.97
chr6_154983150_154983301 0.33 SCAF8
 SR-related CTD-associated factor 8
 71234
 0.12
chr19_17136985_17137234 0.33 CPAMD8
 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
 516
 0.7
chr5_103287875_103288026 0.33 ENSG00000201910
 .
 146625
 0.05
chr2_191883276_191883427 0.33 AC067945.2
671
 0.6
chrX_56792324_56792475 0.33 ENSG00000204272
 .
 36707
 0.23
chr1_111162215_111162656 0.32 KCNA2
 potassium voltage-gated channel, shaker-related subfamily, member 2
 11661
 0.19
chr5_171610252_171610403 0.32 STK10
 serine/threonine kinase 10
 5063
 0.21
chr15_37350605_37350756 0.32 ENSG00000206676
 .
 7549
 0.24
chr11_128566255_128566406 0.32 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 412
 0.82
chr13_100072035_100072186 0.32 ENSG00000266207
 .
 33613
 0.16
chr11_128380151_128380303 0.32 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 4938
 0.27
chr1_29253197_29253478 0.32 EPB41
 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
 12246
 0.18
chr2_8655557_8655708 0.32 AC011747.7
160264
 0.04
chr1_198632521_198632794 0.32 RP11-553K8.5
3533
 0.3
chr3_18484841_18485200 0.32 SATB1
 SATB homeobox 1
 1345
 0.38
chr2_68964970_68965234 0.31 ARHGAP25
 Rho GTPase activating protein 25
 3088
 0.33
chr11_118743547_118743698 0.31 CXCR5
 chemokine (C-X-C motif) receptor 5
 10853
 0.1
chr7_129546585_129546878 0.31 UBE2H
 ubiquitin-conjugating enzyme E2H
 44436
 0.1
chr1_160548800_160549253 0.31 CD84
 CD84 molecule
 237
 0.91
chr10_26727488_26728306 0.31 APBB1IP
 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
 543
 0.85
chr2_219762346_219762497 0.31 WNT10A
 wingless-type MMTV integration site family, member 10A
 15538
 0.1
chr18_12838026_12838271 0.31 PTPN2
 protein tyrosine phosphatase, non-receptor type 2
 1325
 0.51
chr21_26945811_26946271 0.31 ENSG00000234883
 .
 251
 0.92
chr18_60198500_60198651 0.30 ZCCHC2
 zinc finger, CCHC domain containing 2
 7723
 0.28
chr10_135203313_135203500 0.30 RP11-108K14.8
 Mitochondrial GTPase 1
 932
 0.33
chr5_79032666_79032916 0.30 CMYA5
 cardiomyopathy associated 5
 47091
 0.16
chr3_4867321_4867754 0.30 ENSG00000239126
 .
 52849
 0.14
chr2_86080820_86081072 0.30 ST3GAL5
 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
 13831
 0.17
chr7_2559806_2560865 0.30 LFNG
 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
 839
 0.55
chr20_5574610_5574761 0.30 GPCPD1
 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
 16987
 0.24
chrX_147463091_147463259 0.30 AC002368.4
118960
 0.06
chr12_55376808_55376997 0.29 TESPA1
 thymocyte expressed, positive selection associated 1
 1280
 0.52
chr11_67008860_67009245 0.29 KDM2A
 lysine (K)-specific demethylase 2A
 1534
 0.28
chr20_47443528_47443935 0.29 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 689
 0.79
chr1_226921103_226921254 0.29 ITPKB
 inositol-trisphosphate 3-kinase B
 3981
 0.28
chr16_49497467_49497618 0.29 C16orf78
 chromosome 16 open reading frame 78
 89808
 0.09
chr4_71862773_71862924 0.29 DCK
 deoxycytidine kinase
 3493
 0.32
chr6_10529624_10529892 0.29 GCNT2
 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
 1169
 0.49
chr9_21444522_21444673 0.29 IFNA1
 interferon, alpha 1
 4157
 0.18
chr9_82239099_82239364 0.29 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 28277
 0.28
chr1_207090442_207090593 0.29 FAIM3
 Fas apoptotic inhibitory molecule 3
 4695
 0.16
chr7_76541809_76541980 0.29 ENSG00000231183
 .
 1472
 0.46
chr1_9690042_9690512 0.29 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 21513
 0.15
chr9_114836879_114837030 0.29 RP11-4O1.2
36944
 0.14
chr11_128161993_128162144 0.29 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 213221
 0.02
chr20_3137726_3137992 0.29 UBOX5
 U-box domain containing 5
 2663
 0.16
chr6_152506299_152506551 0.28 SYNE1
 spectrin repeat containing, nuclear envelope 1
 16926
 0.28
chr11_94801551_94801758 0.28 ENDOD1
 endonuclease domain containing 1
 21320
 0.19
chr2_10523080_10523233 0.28 HPCAL1
 hippocalcin-like 1
 36991
 0.15
chr8_22301822_22301996 0.28 PPP3CC
 protein phosphatase 3, catalytic subunit, gamma isozyme
 3031
 0.21
chr17_35860978_35861129 0.28 DUSP14
 dual specificity phosphatase 14
 8928
 0.19
chr17_80063977_80064793 0.28 CCDC57
 coiled-coil domain containing 57
 4659
 0.1
chr10_17726067_17726351 0.28 ENSG00000251959
 .
 5022
 0.18
chr1_160174806_160174972 0.28 PEA15
 phosphoprotein enriched in astrocytes 15
 238
 0.51
chr4_109571201_109571501 0.28 OSTC
 oligosaccharyltransferase complex subunit (non-catalytic)
 389
 0.83
chr6_144980546_144980779 0.28 UTRN
 utrophin
 318
 0.95
chr6_45465042_45465193 0.28 RUNX2
 runt-related transcription factor 2
 74895
 0.11
chr15_32634653_32635232 0.28 ENSG00000221444
 .
 50731
 0.09
chr10_5333412_5333586 0.28 AKR1C7P
 aldo-keto reductase family 1, member C7, pseudogene
 3066
 0.27
chr10_111817998_111818272 0.27 ADD3
 adducin 3 (gamma)
 50413
 0.13
chr10_90519770_90519921 0.27 LIPN
 lipase, family member N
 1318
 0.44
chrX_70328757_70329094 0.27 IL2RG
 interleukin 2 receptor, gamma
 193
 0.89
chr16_67399178_67399329 0.27 LRRC36
 leucine rich repeat containing 36
 17947
 0.09
chr12_15104110_15104261 0.27 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
 100
 0.96
chr9_77635535_77635794 0.27 RP11-197P3.5
4712
 0.19

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of RARB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.4 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.6 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.3 GO:0072239 metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.1 0.3 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 1.0 GO:0043368 positive T cell selection(GO:0043368)
0.1 0.7 GO:0002467 germinal center formation(GO:0002467)
0.1 0.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.8 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.2 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.1 0.2 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1 0.3 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.6 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.2 GO:0051458 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:1900121 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0016242 regulation of macroautophagy(GO:0016241) negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.5 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.1 GO:0046325 negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.4 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0002834 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0 0.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.4 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.2 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.2 GO:0042423 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:1902019 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0070076 histone lysine demethylation(GO:0070076)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.0 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.4 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.1 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.1 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0 0.1 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.1 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:0002246 wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0021894 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.0 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.0 GO:0015669 gas transport(GO:0015669)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0001662 behavioral fear response(GO:0001662)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.2 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.0 GO:0042508 tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.0 0.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.0 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.0 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.0 GO:1902803 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.0 GO:0009191 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.0 GO:0032372 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0 0.1 GO:0051828 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.0 GO:0043620 regulation of DNA-templated transcription in response to stress(GO:0043620)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.0 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.1 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.1 GO:0032607 interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727)
0.0 0.1 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.1 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.0 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.0 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0043218 compact myelin(GO:0043218)
0.1 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.3 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0044217 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.2 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.4 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.5 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0032405 MutLalpha complex binding(GO:0032405)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 2.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus