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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for RBPJ

Z-value: 0.45

Motif logo

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Transcription factors associated with RBPJ

Gene Symbol Gene ID Gene Info
RBPJ
ENSG00000168214.16 recombination signal binding protein for immunoglobulin kappa J region

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_26321348_26322561RBPJ2310.964158-0.703.6e-02Click!
chr4_26208180_26208331RBPJ431780.209272-0.646.2e-02Click!
chr4_26095849_26096000RBPJ691530.1335670.637.1e-02Click!
chr4_26301131_26301282RBPJ200780.283044-0.627.3e-02Click!
chr4_26325438_26325589RBPJ10210.699475-0.618.1e-02Click!

Activity of the RBPJ motif across conditions

Conditions sorted by the z-value of the RBPJ motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_119953003_119953290 0.19 TRIM29
 tripartite motif containing 29
 38462
 0.18
chr11_119954900_119955051 0.12 TRIM29
 tripartite motif containing 29
 36633
 0.19
chr11_119954548_119954699 0.12 TRIM29
 tripartite motif containing 29
 36985
 0.19
chr5_63461313_63462499 0.09 RNF180
 ring finger protein 180
 83
 0.99
chr2_54682726_54683239 0.08 SPTBN1
 spectrin, beta, non-erythrocytic 1
 440
 0.88
chr7_99128907_99129569 0.08 FAM200A
 family with sequence similarity 200, member A
 20519
 0.09
chr6_27205685_27206711 0.07 PRSS16
 protease, serine, 16 (thymus)
 9282
 0.19
chrX_84499187_84500398 0.07 ZNF711
 zinc finger protein 711
 21
 0.94
chr19_10218994_10219145 0.06 ENSG00000209645
 .
 742
 0.32
chr9_96108355_96109117 0.06 C9orf129
 chromosome 9 open reading frame 129
 40
 0.98
chr18_7116438_7116788 0.06 LAMA1
 laminin, alpha 1
 1200
 0.55
chr21_46875019_46875466 0.06 COL18A1
 collagen, type XVIII, alpha 1
 161
 0.95
chr19_9524094_9524245 0.06 ZNF266
 zinc finger protein 266
 5588
 0.18
chr13_78493097_78493683 0.06 EDNRB
 endothelin receptor type B
 424
 0.48
chr4_17618154_17618319 0.06 MED28
 mediator complex subunit 28
 1982
 0.25
chr3_64672065_64672629 0.06 ADAMTS9
 ADAM metallopeptidase with thrombospondin type 1 motif, 9
 1008
 0.5
chrX_130036036_130037401 0.06 ENOX2
 ecto-NOX disulfide-thiol exchanger 2
 460
 0.9
chr19_12502733_12502884 0.06 CTD-3105H18.4
8307
 0.12
chr3_140769768_140770253 0.06 SPSB4
 splA/ryanodine receptor domain and SOCS box containing 4
 234
 0.95
chr4_176922498_176923243 0.06 GPM6A
 glycoprotein M6A
 613
 0.78
chr3_71586010_71586190 0.06 ENSG00000221264
 .
 5140
 0.23
chr21_46530236_46530387 0.06 PRED58
4562
 0.17
chr2_105275388_105275738 0.05 ENSG00000207249
 .
 74129
 0.1
chr21_35897414_35897754 0.05 RCAN1
 regulator of calcineurin 1
 102
 0.97
chr6_41605286_41606011 0.05 MDFI
 MyoD family inhibitor
 528
 0.74
chr8_145689855_145691101 0.05 CYHR1
 cysteine/histidine-rich 1
 60
 0.88
chr1_234041439_234041955 0.05 SLC35F3
 solute carrier family 35, member F3
 1018
 0.65
chr12_122460681_122461523 0.05 BCL7A
 B-cell CLL/lymphoma 7A
 1310
 0.49
chr2_159825200_159826543 0.05 TANC1
 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
 688
 0.73
chr2_177392551_177392702 0.05 ENSG00000252027
 .
 136778
 0.04
chr1_173175995_173176483 0.05 TNFSF4
 tumor necrosis factor (ligand) superfamily, member 4
 213
 0.96
chr4_30718989_30719310 0.05 PCDH7
 protocadherin 7
 2888
 0.4
chr8_146156057_146156445 0.05 ZNF16
 zinc finger protein 16
 19730
 0.14
chr4_118904778_118905073 0.05 NDST3
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
 50575
 0.19
chr19_11891380_11891531 0.05 ZNF441
 zinc finger protein 441
 13548
 0.11
chr9_8718682_8718836 0.05 PTPRD
 protein tyrosine phosphatase, receptor type, D
 15135
 0.22
chr16_31438814_31439148 0.05 COX6A2
 cytochrome c oxidase subunit VIa polypeptide 2
 768
 0.46
chr14_104582609_104583337 0.05 ENSG00000207568
 .
 769
 0.59
chr6_24779816_24779967 0.05 GMNN
 geminin, DNA replication inhibitor
 2797
 0.21
chr6_72129322_72130506 0.05 ENSG00000207827
 .
 16590
 0.22
chr16_3273990_3274238 0.05 ZNF200
 zinc finger protein 200
 10956
 0.1
chr4_57973648_57973950 0.05 ENSG00000238541
 .
 1288
 0.36
chr18_25754690_25754841 0.05 CDH2
 cadherin 2, type 1, N-cadherin (neuronal)
 2645
 0.44
chr19_58132756_58132907 0.05 ZNF134
 zinc finger protein 134
 7207
 0.1
chrX_47272886_47273037 0.05 ENSG00000221459
 .
 24913
 0.14
chr13_24607852_24608071 0.05 SPATA13
 spermatogenesis associated 13
 54017
 0.13
chr19_12637235_12637523 0.05 CTD-2192J16.21
6408
 0.12
chr20_2260809_2260960 0.05 TGM3
 transglutaminase 3
 15763
 0.23
chr3_133710186_133710337 0.05 SLCO2A1
 solute carrier organic anion transporter family, member 2A1
 38497
 0.17
chr22_20119477_20120671 0.05 ZDHHC8
 zinc finger, DHHC-type containing 8
 603
 0.53
chr9_128652555_128652706 0.05 PBX3
 pre-B-cell leukemia homeobox 3
 25080
 0.27
chr2_182675706_182676117 0.04 ENSG00000221023
 .
 72578
 0.09
chr1_223351484_223351635 0.04 TLR5
 toll-like receptor 5
 34935
 0.22
chr16_69140450_69141374 0.04 HAS3
 hyaluronan synthase 3
 400
 0.81
chr17_5086107_5086258 0.04 ZNF594
 zinc finger protein 594
 1510
 0.3
chr18_908458_909079 0.04 RP11-672L10.3
1087
 0.42
chr2_28565345_28565858 0.04 AC093690.1
32275
 0.15
chr12_122884907_122885085 0.04 CLIP1
 CAP-GLY domain containing linker protein 1
 435
 0.86
chr4_11652300_11652527 0.04 HS3ST1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
 221024
 0.02
chr19_58050211_58050362 0.04 ZNF550
 zinc finger protein 550
 9075
 0.1
chr19_12256353_12256531 0.04 ZNF625
 zinc finger protein 625
 2175
 0.18
chr4_187648163_187648374 0.04 FAT1
 FAT atypical cadherin 1
 392
 0.92
chr6_79902044_79902327 0.04 HMGN3-AS1
 HMGN3 antisense RNA 1
 41250
 0.16
chr4_186130212_186131033 0.04 KIAA1430
 KIAA1430
 36
 0.92
chr18_21198891_21199952 0.04 ANKRD29
 ankyrin repeat domain 29
 30065
 0.14
chr10_25836306_25836457 0.04 ENSG00000222543
 .
 153608
 0.04
chr10_115860454_115861476 0.04 ENSG00000253066
 .
 10208
 0.2
chr12_133780930_133781187 0.04 AC226150.4
 Uncharacterized protein
 6714
 0.13
chr11_66153976_66154134 0.04 ENSG00000202317
 .
 6865
 0.08
chr11_119953470_119953621 0.04 TRIM29
 tripartite motif containing 29
 38063
 0.18
chr11_8615266_8616201 0.04 STK33
 serine/threonine kinase 33
 26
 0.97
chr2_105475725_105475876 0.04 POU3F3
 POU class 3 homeobox 3
 3831
 0.16
chr10_72217935_72218559 0.04 NODAL
 nodal growth differentiation factor
 10540
 0.17
chr13_88329839_88330831 0.04 SLITRK5
 SLIT and NTRK-like family, member 5
 4837
 0.33
chr3_46263422_46263573 0.04 CCR1
 chemokine (C-C motif) receptor 1
 13610
 0.2
chr19_58774047_58774198 0.04 CTD-3138B18.6
3879
 0.12
chr19_46572119_46572325 0.04 IGFL4
 IGF-like family member 4
 8130
 0.15
chr19_58265433_58265584 0.04 ZNF776
 zinc finger protein 776
 3336
 0.12
chrX_19140154_19140583 0.04 GPR64
 G protein-coupled receptor 64
 211
 0.97
chr5_180277181_180277332 0.04 ZFP62
 ZFP62 zinc finger protein
 10407
 0.16
chr19_460012_460518 0.04 SHC2
 SHC (Src homology 2 domain containing) transforming protein 2
 731
 0.5
chr5_68788670_68789791 0.04 OCLN
 occludin
 612
 0.62
chr13_20175736_20176974 0.04 MPHOSPH8
 M-phase phosphoprotein 8
 31433
 0.18
chr1_218672576_218672996 0.04 C1orf143
 chromosome 1 open reading frame 143
 10652
 0.26
chr19_52469059_52469210 0.04 ZNF350
 zinc finger protein 350
 8972
 0.12
chr19_58945059_58945210 0.04 ZNF132
 zinc finger protein 132
 6455
 0.08
chr12_120142120_120142271 0.04 RP1-127H14.3
 Uncharacterized protein
 4622
 0.19
chr8_61193398_61193986 0.04 CA8
 carbonic anhydrase VIII
 279
 0.95
chr19_12016806_12016962 0.04 ZNF69
 zinc finger protein 69
 18214
 0.1
chr2_145210039_145210510 0.04 ZEB2
 zinc finger E-box binding homeobox 2
 22137
 0.25
chr19_11833281_11833438 0.04 CTC-499B15.6
8239
 0.13
chr12_32135997_32136148 0.04 KIAA1551
 KIAA1551
 20649
 0.22
chr18_64307786_64307937 0.04 ENSG00000221536
 .
 12877
 0.26
chr1_178063691_178064117 0.04 RASAL2
 RAS protein activator like 2
 628
 0.84
chr21_48087065_48088237 0.04 PRMT2
 protein arginine methyltransferase 2
 23396
 0.22
chr19_58773538_58773689 0.04 CTD-3138B18.6
4388
 0.11
chr7_5634981_5635198 0.04 FSCN1
 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
 772
 0.6
chr21_16424202_16424355 0.04 NRIP1
 nuclear receptor interacting protein 1
 12848
 0.26
chr7_93519153_93519436 0.04 TFPI2
 tissue factor pathway inhibitor 2
 188
 0.88
chr5_123985243_123985413 0.04 RP11-436H11.2
79196
 0.08
chr2_153325586_153326000 0.04 FMNL2
 formin-like 2
 134042
 0.05
chr9_99521835_99521986 0.04 ZNF510
 zinc finger protein 510
 18418
 0.24
chr6_72206174_72206487 0.03 ENSG00000212099
 .
 42349
 0.17
chr2_232479090_232479920 0.03 C2orf57
 chromosome 2 open reading frame 57
 21930
 0.15
chr12_133779073_133779476 0.03 AC226150.4
 Uncharacterized protein
 8498
 0.13
chr19_58689540_58689691 0.03 ZNF274
 zinc finger protein 274
 4781
 0.15
chr10_60273912_60274168 0.03 BICC1
 bicaudal C homolog 1 (Drosophila)
 1140
 0.65
chr12_102225232_102225392 0.03 GNPTAB
 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
 596
 0.63
chr2_103235205_103235939 0.03 SLC9A2
 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
 594
 0.82
chr2_121103939_121104858 0.03 INHBB
 inhibin, beta B
 679
 0.78
chr13_45146605_45146867 0.03 TSC22D1
 TSC22 domain family, member 1
 3656
 0.33
chr19_2933699_2933850 0.03 AC006277.2
6969
 0.12
chr10_18655851_18656002 0.03 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
 26260
 0.24
chr12_13492233_13492384 0.03 C12orf36
 chromosome 12 open reading frame 36
 37056
 0.18
chr16_74734045_74735115 0.03 MLKL
 mixed lineage kinase domain-like
 108
 0.97
chr19_11892320_11892471 0.03 ZNF441
 zinc finger protein 441
 14488
 0.11
chr16_72459537_72459688 0.03 ENSG00000207514
 .
 49009
 0.17
chr2_48476024_48476175 0.03 ENSG00000201010
 .
 31385
 0.2
chr13_107572015_107572438 0.03 ENSG00000239050
 .
 55148
 0.17
chr15_83679247_83679398 0.03 C15orf40
 chromosome 15 open reading frame 40
 1015
 0.36
chr1_224686385_224686769 0.03 WDR26
 WD repeat domain 26
 61842
 0.11
chr3_141131899_141132175 0.03 ZBTB38
 zinc finger and BTB domain containing 38
 10377
 0.23
chr1_81137188_81137522 0.03 ENSG00000266033
 .
 342182
 0.01
chr19_9639561_9639712 0.03 ZNF426
 zinc finger protein 426
 7609
 0.17
chr16_3432968_3433133 0.03 MTRNR2L4
 MT-RNR2-like 4
 10767
 0.11
chr5_4082877_4083178 0.03 CTD-2012M11.3
482725
 0.01
chr19_44514850_44515001 0.03 ZNF230
 zinc finger protein 230
 4073
 0.12
chr5_149524115_149524266 0.03 PDGFRB
 platelet-derived growth factor receptor, beta polypeptide
 7190
 0.15
chr3_158508847_158509075 0.03 RP11-379F4.8
8625
 0.16
chr5_180278006_180278157 0.03 ZFP62
 ZFP62 zinc finger protein
 9582
 0.17
chr3_119030384_119030661 0.03 ARHGAP31-AS1
 ARHGAP31 antisense RNA 1
 11085
 0.16
chr9_110013679_110013830 0.03 RAD23B
 RAD23 homolog B (S. cerevisiae)
 31664
 0.23
chr17_5085116_5085307 0.03 ZNF594
 zinc finger protein 594
 2481
 0.2
chr5_159797706_159797884 0.03 C1QTNF2
 C1q and tumor necrosis factor related protein 2
 147
 0.95
chr6_10586335_10586486 0.03 GCNT2
 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
 431
 0.84
chr10_98455004_98455155 0.03 PIK3AP1
 phosphoinositide-3-kinase adaptor protein 1
 25192
 0.18
chr5_58958074_58958460 0.03 ENSG00000202601
 .
 41262
 0.2
chr15_75339241_75339413 0.03 PPCDC
 phosphopantothenoylcysteine decarboxylase
 3711
 0.2
chr11_12063788_12063939 0.03 DKK3
 dickkopf WNT signaling pathway inhibitor 3
 32547
 0.2
chr7_41740779_41741576 0.03 INHBA
 inhibin, beta A
 970
 0.56
chr1_236046770_236047092 0.03 LYST
 lysosomal trafficking regulator
 59
 0.97
chr5_124079913_124080218 0.03 ZNF608
 zinc finger protein 608
 149
 0.94
chr17_47987589_47988019 0.03 ENSG00000199492
 .
 55736
 0.08
chr17_60885608_60885921 0.03 MARCH10
 membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
 59
 0.98
chr10_91274995_91275346 0.03 SLC16A12
 solute carrier family 16, member 12
 20143
 0.18
chr16_3108546_3109349 0.03 RP11-473M20.7
139
 0.86
chr1_21900562_21900713 0.03 ALPL
 alkaline phosphatase, liver/bone/kidney
 334
 0.87
chr5_9544908_9545592 0.03 SEMA5A
 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
 937
 0.56
chr8_21914018_21914169 0.03 DMTN
 dematin actin binding protein
 323
 0.82
chr6_15297900_15298051 0.03 ENSG00000201367
 .
 17176
 0.18
chr15_58767167_58767318 0.03 ALDH1A2
 aldehyde dehydrogenase 1 family, member A2
 1130
 0.49
chr11_47586558_47587254 0.03 PTPMT1
 protein tyrosine phosphatase, mitochondrial 1
 76
 0.59
chr1_205343234_205343399 0.03 LEMD1-AS1
 LEMD1 antisense RNA 1
 936
 0.53
chr4_156681206_156681472 0.03 GUCY1B3
 guanylate cyclase 1, soluble, beta 3
 728
 0.72
chr9_34047108_34047259 0.03 UBAP2
 ubiquitin associated protein 2
 1700
 0.27
chr21_36594684_36594936 0.03 RUNX1
 runt-related transcription factor 1
 173169
 0.04
chr19_2933350_2933631 0.03 AC006277.2
6685
 0.12
chr7_50321625_50321823 0.03 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 22600
 0.25
chr4_70108820_70108971 0.03 UGT2B11
 UDP glucuronosyltransferase 2 family, polypeptide B11
 28446
 0.16
chr19_58772914_58773185 0.03 CTD-3138B18.6
4952
 0.11
chr8_1993393_1993636 0.03 MYOM2
 myomesin 2
 330
 0.93
chr19_58370756_58370907 0.03 ZNF587
 zinc finger protein 587
 3494
 0.13
chr18_42044646_42044797 0.03 SETBP1
 SET binding protein 1
 215417
 0.02
chr19_20117293_20117444 0.03 ZNF682
 zinc finger protein 682
 703
 0.66
chr19_38229308_38229579 0.03 ZNF607
 zinc finger protein 607
 18752
 0.15
chr6_142699302_142699594 0.03 GPR126
 G protein-coupled receptor 126
 12001
 0.29
chr19_35448920_35449083 0.03 ZNF792
 zinc finger protein 792
 2606
 0.2
chr14_65184455_65184704 0.03 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
 2158
 0.36
chr19_12541727_12541878 0.03 CTD-3105H18.16
 Uncharacterized protein
 10094
 0.11
chr6_28504701_28505374 0.03 GPX5
 glutathione peroxidase 5 (epididymal androgen-related protein)
 11248
 0.17
chr9_124414074_124414751 0.03 DAB2IP
 DAB2 interacting protein
 539
 0.84
chr4_149137803_149137954 0.03 RP11-76G10.1
70256
 0.13
chr1_15251371_15251898 0.03 KAZN
 kazrin, periplakin interacting protein
 1008
 0.7
chrX_19687578_19687729 0.03 SH3KBP1
 SH3-domain kinase binding protein 1
 827
 0.76
chr6_7469002_7469180 0.03 RP3-512B11.3
72480
 0.09
chr5_80716043_80716194 0.03 ACOT12
 acyl-CoA thioesterase 12
 26120
 0.23
chr3_14853690_14853962 0.03 FGD5
 FYVE, RhoGEF and PH domain containing 5
 6643
 0.24
chr15_62402344_62402495 0.03 C2CD4A
 C2 calcium-dependent domain containing 4A
 43243
 0.13
chr10_95333061_95333288 0.03 FFAR4
 free fatty acid receptor 4
 6735
 0.17
chr1_247201400_247201551 0.03 ZNF695
 zinc finger protein 695
 30080
 0.15
chr2_144499859_144500010 0.03 RP11-434H14.1
1071
 0.59
chr4_184826206_184826847 0.03 STOX2
 storkhead box 2
 17
 0.99
chr2_95880533_95880684 0.03 ZNF2
 zinc finger protein 2
 49046
 0.12
chr6_113953461_113953992 0.03 ENSG00000266650
 .
 29609
 0.21
chr5_92924582_92924758 0.03 ENSG00000237187
 .
 3316
 0.26
chr16_72882732_72883241 0.03 ENSG00000251868
 .
 27095
 0.17
chr6_90796198_90796349 0.03 ENSG00000222078
 .
 85048
 0.09
chr14_74222749_74222900 0.03 ELMSAN1
 ELM2 and Myb/SANT-like domain containing 1
 1105
 0.36
chr12_49392080_49393040 0.03 RP11-386G11.5
379
 0.49
chr2_220251514_220252585 0.03 DNPEP
 aspartyl aminopeptidase
 19
 0.94
chr19_58861430_58861581 0.03 A1BG-AS1
 A1BG antisense RNA 1
 1831
 0.13
chr9_112889621_112889772 0.03 AKAP2
 A kinase (PRKA) anchor protein 2
 1915
 0.45
chr7_36195246_36195841 0.03 EEPD1
 endonuclease/exonuclease/phosphatase family domain containing 1
 2666
 0.32
chr4_139941093_139941244 0.03 ENSG00000264953
 .
 2435
 0.22
chr9_12775957_12776199 0.03 LURAP1L
 leucine rich adaptor protein 1-like
 1058
 0.54
chr20_55363223_55363386 0.03 ENSG00000207158
 .
 2161
 0.37
chr5_159738704_159739455 0.03 CCNJL
 cyclin J-like
 404
 0.84
chr10_110225810_110226152 0.03 ENSG00000222436
 .
 475087
 0.01
chr9_129467466_129467647 0.03 ENSG00000266403
 .
 13056
 0.21
chr1_15575745_15575896 0.03 FHAD1
 forkhead-associated (FHA) phosphopeptide binding domain 1
 2044
 0.36

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)