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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for REL

Z-value: 1.07

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Transcription factors associated with REL

Gene Symbol	Gene ID	Gene Info
REL Ensembl NCBI GeneCards UniProt	ENSG00000162924.9	REL proto-oncogene, NF-kB subunit

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_61108808_61109533	REL	379	0.867969	0.69	4.1e-02	Click!
chr2_61109789_61110469	REL	1338	0.449024	0.57	1.1e-01	Click!
chr2_61094888_61095039	REL	13693	0.184224	-0.51	1.6e-01	Click!
chr2_61093725_61093876	REL	14856	0.181757	-0.51	1.6e-01	Click!
chr2_61111507_61111691	REL	2808	0.268150	0.49	1.9e-01	Click!

Activity of the REL motif across conditions

Conditions sorted by the z-value of the REL motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr20_4795121_4795462	0.70	RASSF2	Ras association (RalGDS/AF-6) domain family member 2	478	0.82
chr13_31309966_31310295	0.62	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	485	0.88
chr12_76425402_76425553	0.61	PHLDA1	pleckstrin homology-like domain, family A, member 1	93	0.95
chr9_117145261_117145418	0.56	AKNA	AT-hook transcription factor	4904	0.23
chr11_69065156_69065401	0.53	MYEOV	myeloma overexpressed	3653	0.34
chr4_100738641_100738957	0.52	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	796	0.72
chr9_123688442_123688941	0.52	TRAF1	TNF receptor-associated factor 1	2356	0.33
chr12_55375572_55375878	0.52	TESPA1	thymocyte expressed, positive selection associated 1	103	0.98
chr12_122228420_122228575	0.52	RHOF	ras homolog family member F (in filopodia)	2769	0.23
chr17_41738065_41738244	0.50	MEOX1	mesenchyme homeobox 1	777	0.64
chr21_32554686_32554857	0.50	TIAM1	T-cell lymphoma invasion and metastasis 1	52232	0.17
chr8_59717634_59717850	0.49	ENSG00000201231	.	9369	0.29
chr7_30766706_30766866	0.48	INMT	indolethylamine N-methyltransferase	24965	0.16
chr12_2977204_2977355	0.48	FOXM1	forkhead box M1	468	0.67
chr6_138028959_138029110	0.48	ENSG00000216097	.	9051	0.27
chr19_49362125_49362344	0.47	PLEKHA4	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	397	0.71
chr17_46506744_46506936	0.46	SKAP1	src kinase associated phosphoprotein 1	712	0.61
chr22_37881738_37882044	0.46	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	534	0.71
chr1_9688741_9688898	0.45	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	22971	0.15
chr14_22994691_22994955	0.44	TRAJ15	T cell receptor alpha joining 15	3757	0.14
chr20_48419063_48419214	0.43	ENSG00000252540	.	7790	0.16
chr1_160766445_160766727	0.43	LY9	lymphocyte antigen 9	609	0.72
chr3_50644253_50644482	0.43	CISH	cytokine inducible SH2-containing protein	4836	0.16
chr6_9521344_9521640	0.42	OFCC1	orofacial cleft 1 candidate 1	412008	0.01
chr1_31227757_31227908	0.42	LAPTM5	lysosomal protein transmembrane 5	2835	0.23
chr19_39106930_39107372	0.42	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	1413	0.27
chr16_28996496_28996848	0.41	LAT	linker for activation of T cells	11	0.94
chr22_17568454_17568717	0.41	IL17RA	interleukin 17 receptor A	2736	0.23
chr1_26316985_26317339	0.41	PAFAH2	platelet-activating factor acetylhydrolase 2, 40kDa	6950	0.1
chrX_76776329_76776480	0.40	FGF16	fibroblast growth factor 16	66756	0.13
chrX_53741093_53741244	0.39	HUWE1	HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase	27495	0.23
chr14_84023285_84023436	0.39	ENSG00000238561	.	193368	0.03
chrX_123480814_123480965	0.39	SH2D1A	SH2 domain containing 1A	450	0.9
chr15_81586254_81586487	0.38	IL16	interleukin 16	2884	0.28
chr9_134143747_134144006	0.38	FAM78A	family with sequence similarity 78, member A	2004	0.31
chr21_44036816_44036993	0.38	AP001626.2		34450	0.13
chr3_195913428_195913625	0.38	ENSG00000222335	.	15694	0.13
chr6_11852612_11852763	0.37	ADTRP	androgen-dependent TFPI-regulating protein	45408	0.18
chr21_42739358_42739509	0.37	MX2	myxovirus (influenza virus) resistance 2 (mouse)	2579	0.29
chr1_167599991_167600483	0.37	RP3-455J7.4		326	0.69
chr1_24830480_24830703	0.37	RCAN3	RCAN family member 3	1204	0.45
chr1_150737104_150737638	0.37	CTSS	cathepsin S	897	0.5
chr9_134154077_134154228	0.37	FAM78A	family with sequence similarity 78, member A	2218	0.29
chr12_9913587_9913738	0.37	CD69	CD69 molecule	165	0.94
chr13_34184837_34185306	0.37	RFC3	replication factor C (activator 1) 3, 38kDa	207115	0.02
chr1_8000859_8001010	0.37	TNFRSF9	tumor necrosis factor receptor superfamily, member 9	8	0.98
chr12_104856651_104856876	0.37	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	5984	0.3
chr9_134604865_134605016	0.37	ENSG00000240853	.	4086	0.24
chr16_80690406_80690960	0.36	ENSG00000265341	.	8777	0.18
chr13_74807358_74807666	0.36	ENSG00000206617	.	55839	0.16
chr5_40490586_40490737	0.36	ENSG00000199552	.	164404	0.03
chr22_50631230_50631436	0.36	TRABD	TraB domain containing	110	0.82
chr17_61920040_61920386	0.35	SMARCD2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2	87	0.94
chr7_44790648_44790799	0.35	ZMIZ2	zinc finger, MIZ-type containing 2	2193	0.28
chr17_8643854_8644020	0.35	CCDC42	coiled-coil domain containing 42	4168	0.22
chr17_72735282_72735631	0.35	RAB37	RAB37, member RAS oncogene family	2085	0.18
chr17_40440128_40440459	0.35	STAT5A	signal transducer and activator of transcription 5A	194	0.91
chr3_71833354_71833608	0.34	PROK2	prokineticin 2	731	0.68
chr11_64636867_64637025	0.34	EHD1	EH-domain containing 1	6192	0.1
chr3_33800152_33800303	0.34	PDCD6IP	programmed cell death 6 interacting protein	39617	0.18
chr17_56421831_56421982	0.34	SUPT4H1	suppressor of Ty 4 homolog 1 (S. cerevisiae)	7116	0.11
chr9_139927070_139927409	0.34	FUT7	fucosyltransferase 7 (alpha (1,3) fucosyltransferase)	223	0.78
chr6_119029777_119030724	0.34	CEP85L	centrosomal protein 85kDa-like	981	0.69
chr6_10532255_10532677	0.33	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)	3877	0.23
chr16_1013980_1014176	0.33	LMF1	lipase maturation factor 1	44	0.96
chr1_93443435_93443586	0.33	ENSG00000239710	.	2830	0.16
chr20_55967108_55967259	0.33	RBM38	RNA binding motif protein 38	103	0.93
chr1_66799510_66799957	0.33	PDE4B	phosphodiesterase 4B, cAMP-specific	1861	0.5
chr19_59077926_59078077	0.33	MZF1	myeloid zinc finger 1	6141	0.08
chr1_154926399_154926550	0.33	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	2106	0.14
chr1_166459489_166459697	0.33	FAM78B	family with sequence similarity 78, member B	323387	0.01
chr4_56814187_56814608	0.33	CEP135	centrosomal protein 135kDa	640	0.74
chr22_37563414_37563565	0.32	RP1-151B14.6		692	0.56
chr21_42741228_42741619	0.32	MX2	myxovirus (influenza virus) resistance 2 (mouse)	589	0.77
chr8_126964027_126964178	0.32	ENSG00000206695	.	50907	0.19
chr4_10734070_10734358	0.32	CLNK	cytokine-dependent hematopoietic cell linker	47725	0.2
chr2_87782164_87782461	0.32	RP11-1399P15.1		4759	0.34
chr3_49314185_49314445	0.32	C3orf62	chromosome 3 open reading frame 62	337	0.78
chr9_132650035_132650502	0.32	FNBP1	formin binding protein 1	31321	0.13
chr19_16439255_16439417	0.32	KLF2	Kruppel-like factor 2	3685	0.18
chr22_44392181_44392448	0.32	PARVB	parvin, beta	2777	0.29
chr21_35305474_35305968	0.31	LINC00649	long intergenic non-protein coding RNA 649	2203	0.25
chr17_3865236_3865510	0.31	ATP2A3	ATPase, Ca++ transporting, ubiquitous	2212	0.29
chr15_31638589_31638828	0.31	KLF13	Kruppel-like factor 13	6572	0.32
chr1_19254411_19254592	0.31	IFFO2	intermediate filament family orphan 2	16015	0.16
chr2_214108249_214108400	0.31	SPAG16	sperm associated antigen 16	40789	0.21
chr10_15367555_15367706	0.31	FAM171A1	family with sequence similarity 171, member A1	45428	0.17
chr2_113932280_113932569	0.31	AC016683.5		490	0.59
chr22_30475055_30475206	0.31	HORMAD2	HORMA domain containing 2	1033	0.38
chr17_14207181_14207332	0.31	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	2856	0.35
chr20_3888044_3888195	0.31	ENSG00000199024	.	10022	0.14
chr20_827167_827339	0.31	FAM110A	family with sequence similarity 110, member A	1486	0.47
chr11_46141542_46141818	0.31	PHF21A	PHD finger protein 21A	267	0.92
chrX_57936749_57936967	0.31	ZXDA	zinc finger, X-linked, duplicated A	209	0.97
chr5_39199802_39200193	0.30	FYB	FYN binding protein	3132	0.36
chr16_14109259_14109410	0.30	MKL2	MKL/myocardin-like 2	55844	0.14
chr3_150917377_150917528	0.30	GPR171	G protein-coupled receptor 171	3527	0.19
chr3_134515712_134515902	0.30	EPHB1	EPH receptor B1	824	0.64
chr9_35649649_35650491	0.30	SIT1	signaling threshold regulating transmembrane adaptor 1	867	0.32
chr5_1105065_1105874	0.30	SLC12A7	solute carrier family 12 (potassium/chloride transporter), member 7	6681	0.19
chrX_123373984_123374135	0.30	ENSG00000252693	.	42466	0.19
chr6_119450513_119450664	0.30	FAM184A	family with sequence similarity 184, member A	19764	0.22
chr20_11435441_11435592	0.30	ENSG00000222281	.	364223	0.01
chr18_46477576_46477867	0.30	SMAD7	SMAD family member 7	640	0.78
chr6_135501734_135502104	0.30	MYB	v-myb avian myeloblastosis viral oncogene homolog	534	0.78
chr8_23075544_23076103	0.30	ENSG00000246582	.	6161	0.12
chr19_46148940_46149188	0.30	EML2	echinoderm microtubule associated protein like 2	177	0.87
chr2_238604951_238605166	0.29	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	4076	0.27
chr16_14380187_14380356	0.29	ENSG00000201075	.	10909	0.18
chr8_79716569_79716762	0.29	IL7	interleukin 7	498	0.88
chr14_93427433_93427584	0.29	CHGA	chromogranin A (parathyroid secretory protein 1)	37987	0.18
chr1_156023968_156024197	0.29	LAMTOR2	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	461	0.42
chr2_202129112_202129390	0.29	CASP8	caspase 8, apoptosis-related cysteine peptidase	2572	0.28
chr8_37751638_37751789	0.29	RAB11FIP1	RAB11 family interacting protein 1 (class I)	5259	0.15
chr17_46969511_46969711	0.29	ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)	516	0.65
chr19_4338579_4338993	0.29	STAP2	signal transducing adaptor family member 2	20	0.91
chr17_70418844_70419055	0.29	ENSG00000200783	.	241342	0.02
chr1_147229260_147229411	0.29	RP11-433J22.2		91	0.97
chr2_96455429_96455580	0.29	AC008268.2		2464	0.4
chr6_135484621_135484772	0.29	MYB	v-myb avian myeloblastosis viral oncogene homolog	17757	0.18
chr15_45409056_45409207	0.28	DUOX2	dual oxidase 2	2589	0.14
chr16_26606103_26606254	0.28	ENSG00000264935	.	141372	0.05
chr21_45564255_45564539	0.28	C21orf33	chromosome 21 open reading frame 33	8396	0.15
chrX_40429955_40430133	0.28	ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2	10102	0.21
chr10_47640402_47640757	0.28	ANTXRLP1	anthrax toxin receptor-like pseudogene 1	4212	0.25
chr1_155220339_155220564	0.28	FAM189B	family with sequence similarity 189, member B	4248	0.07
chr2_10548224_10548465	0.28	HPCAL1	hippocalcin-like 1	11803	0.19
chr17_7819751_7819902	0.28	AC025335.1		555	0.56
chr16_83377985_83378136	0.28	RP11-543N12.1		53532	0.15
chr16_11678014_11678655	0.28	LITAF	lipopolysaccharide-induced TNF factor	1895	0.35
chr13_28363625_28363776	0.28	GSX1	GS homeobox 1	3080	0.29
chr9_100854419_100854570	0.28	TRIM14	tripartite motif containing 14	349	0.87
chr9_117969296_117969447	0.27	DEC1	deleted in esophageal cancer 1	65274	0.14
chr17_66286056_66286766	0.27	SLC16A6	solute carrier family 16, member 6	846	0.47
chr20_35272612_35272763	0.27	SLA2	Src-like-adaptor 2	1597	0.3
chr21_32930574_32931128	0.27	TIAM1	T-cell lymphoma invasion and metastasis 1	439	0.64
chr10_73119134_73119285	0.27	ENSG00000238918	.	34124	0.15
chrX_128915626_128915992	0.27	SASH3	SAM and SH3 domain containing 3	1849	0.35
chrX_9979270_9979421	0.27	WWC3	WWC family member 3	4257	0.22
chr18_13465441_13465744	0.27	LDLRAD4	low density lipoprotein receptor class A domain containing 4	578	0.59
chr10_15211128_15211858	0.27	NMT2	N-myristoyltransferase 2	801	0.67
chr12_56881156_56881307	0.27	GLS2	glutaminase 2 (liver, mitochondrial)	671	0.58
chr17_76642017_76642260	0.27	ENSG00000252391	.	50741	0.12
chr17_74523964_74524115	0.27	CYGB	cytoglobin	4108	0.1
chr11_2322055_2322323	0.27	C11orf21	chromosome 11 open reading frame 21	954	0.34
chr5_96232081_96232313	0.27	ERAP2	endoplasmic reticulum aminopeptidase 2	7276	0.18
chr6_138191751_138192709	0.26	RP11-356I2.4		2860	0.28
chr3_195839047_195839198	0.26	TFRC	transferrin receptor	30062	0.14
chr19_4015164_4015315	0.26	PIAS4	protein inhibitor of activated STAT, 4	7595	0.11
chr3_32502059_32502315	0.26	CMTM6	CKLF-like MARVEL transmembrane domain containing 6	42713	0.15
chr1_151735692_151735974	0.26	OAZ3	ornithine decarboxylase antizyme 3	123	0.48
chrX_102565057_102565303	0.26	BEX2	brain expressed X-linked 2	683	0.63
chr4_38320716_38321108	0.26	ENSG00000221495	.	80678	0.11
chr8_1953776_1953973	0.26	KBTBD11	kelch repeat and BTB (POZ) domain containing 11	31830	0.2
chr9_139424881_139425156	0.26	ENSG00000263403	.	10940	0.09
chr13_50698385_50698672	0.26	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	42221	0.15
chr8_8202203_8202575	0.26	SGK223	Tyrosine-protein kinase SgK223	36868	0.18
chr2_201987300_201987657	0.26	CFLAR	CASP8 and FADD-like apoptosis regulator	278	0.87
chr11_104971227_104972126	0.26	CASP1	caspase 1, apoptosis-related cysteine peptidase	482	0.32
chr18_43268798_43268949	0.26	SLC14A2	solute carrier family 14 (urea transporter), member 2	22766	0.16
chr18_42306038_42306201	0.26	SETBP1	SET binding protein 1	28990	0.26
chr11_65341832_65341983	0.26	EHBP1L1	EH domain binding protein 1-like 1	1602	0.16
chr11_441985_442183	0.26	ANO9	anoctamin 9	73	0.92
chr1_6520532_6520815	0.26	TNFRSF25	tumor necrosis factor receptor superfamily, member 25	5017	0.12
chr1_151030425_151030576	0.26	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	266	0.79
chr1_117297247_117297398	0.26	CD2	CD2 molecule	233	0.94
chr9_100820741_100820957	0.26	NANS	N-acetylneuraminic acid synthase	1828	0.32
chr9_140213393_140213574	0.26	NRARP	NOTCH-regulated ankyrin repeat protein	16780	0.09
chr2_179896702_179896868	0.26	ENSG00000252000	.	8680	0.23
chr15_45493492_45493643	0.26	SHF	Src homology 2 domain containing F	194	0.81
chr12_24893684_24893835	0.26	ENSG00000240481	.	34037	0.21
chr10_12085427_12085707	0.26	UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)	544	0.77
chr7_5863313_5863517	0.26	ZNF815P	zinc finger protein 815, pseudogene	577	0.73
chr16_32199480_32199834	0.25	HERC2P4	hect domain and RLD 2 pseudogene 4	223	0.95
chr7_74057672_74058172	0.25	GTF2I	general transcription factor IIi	14089	0.22
chrX_48793999_48794379	0.25	PIM2	pim-2 oncogene	17888	0.08
chr1_226922169_226922483	0.25	ITPKB	inositol-trisphosphate 3-kinase B	2833	0.32
chr9_37529043_37529220	0.25	RP11-613M10.6		19984	0.15
chr16_68798920_68799109	0.25	ENSG00000200558	.	22631	0.14
chr19_45271245_45271464	0.25	ENSG00000253027	.	3147	0.15
chr19_39825870_39826313	0.25	GMFG	glia maturation factor, gamma	554	0.58
chr1_40781658_40781894	0.25	COL9A2	collagen, type IX, alpha 2	586	0.72
chr9_38227227_38227501	0.25	ENSG00000238313	.	36960	0.19
chr19_41869552_41869735	0.25	TMEM91	transmembrane protein 91	318	0.54
chr12_109022749_109023024	0.25	RP11-689B22.2		423	0.76
chr9_116139439_116139752	0.25	HDHD3	haloacid dehalogenase-like hydrolase domain containing 3	316	0.84
chr2_202101089_202101263	0.25	CASP8	caspase 8, apoptosis-related cysteine peptidase	2947	0.25
chr11_34255826_34255987	0.25	ENSG00000201867	.	45185	0.17
chr11_69457554_69457705	0.25	CCND1	cyclin D1	1655	0.41
chr17_47819247_47819793	0.25	FAM117A	family with sequence similarity 117, member A	17631	0.14
chr1_113162566_113162826	0.24	ST7L	suppression of tumorigenicity 7 like	656	0.47
chr3_112215334_112215665	0.24	BTLA	B and T lymphocyte associated	2706	0.33
chr17_75103749_75103900	0.24	ENSG00000234912	.	18435	0.18
chr7_134855680_134855894	0.24	C7orf49	chromosome 7 open reading frame 49	240	0.89
chr7_5183512_5184010	0.24	ZNF890P	zinc finger protein 890, pseudogene	16335	0.17
chr17_4850386_4850673	0.24	PFN1	profilin 1	235	0.73
chr13_71865361_71865710	0.24	DACH1	dachshund homolog 1 (Drosophila)	575372	0.0
chr2_106363775_106364396	0.24	NCK2	NCK adaptor protein 2	1897	0.48
chrX_100183468_100183619	0.24	XKRX	XK, Kell blood group complex subunit-related, X-linked	355	0.88
chr16_28152825_28152997	0.24	XPO6	exportin 6	28311	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.4	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.4	GO:0072338	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.3	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.1	0.3	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.3	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.4	GO:0034629	cellular protein complex localization(GO:0034629)
0.1	0.3	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.5	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	0.3	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.2	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.1	0.2	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.2	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.2	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1	0.2	GO:0097205	regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.1	0.3	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.1	0.1	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1	0.3	GO:0001757	somite specification(GO:0001757)
0.1	0.3	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.1	0.2	GO:0016048	detection of temperature stimulus(GO:0016048)
0.1	0.1	GO:0070254	mucus secretion(GO:0070254)
0.1	0.3	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.1	0.2	GO:0032682	negative regulation of chemokine production(GO:0032682)
0.1	0.1	GO:0002830	positive regulation of type 2 immune response(GO:0002830) positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1	0.3	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.1	0.3	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.1	0.2	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.1	0.1	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	0.2	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.1	0.1	GO:1903519	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1	0.5	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1	0.1	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.1	0.2	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.1	0.2	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1	0.2	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.2	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1	0.2	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.1	0.2	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.1	0.2	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.1	0.2	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.1	0.2	GO:0070141	response to UV-A(GO:0070141)
0.0	0.2	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.2	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.3	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.2	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0052169	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.2	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0060087	relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.2	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.4	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.2	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.3	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.4	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.5	GO:0002279	mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0	0.1	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.0	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0	0.2	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.2	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0060872	semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0051323	metaphase(GO:0051323)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.4	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.0	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.1	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475)
0.0	0.1	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0021554	optic nerve development(GO:0021554)
0.0	0.2	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.3	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0032329	serine transport(GO:0032329)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.4	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.6	GO:0032873	negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.2	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.0	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.2	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.1	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.3	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.1	GO:0032649	regulation of interferon-gamma production(GO:0032649)
0.0	0.1	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.3	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0001820	serotonin secretion(GO:0001820)
0.0	0.2	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.1	GO:0016241	regulation of macroautophagy(GO:0016241) negative regulation of macroautophagy(GO:0016242)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.0	GO:0070076	histone lysine demethylation(GO:0070076)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.2	GO:0032735	positive regulation of interleukin-12 production(GO:0032735)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.5	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.4	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.2	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.2	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.4	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.0	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.0	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.2	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.1	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.0	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.0	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.0	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.5	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.0	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0035067	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.3	GO:0006541	glutamine metabolic process(GO:0006541)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.0	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.0	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.1	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.0	0.3	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.8	GO:0006968	cellular defense response(GO:0006968)
0.0	0.1	GO:0048302	regulation of isotype switching to IgG isotypes(GO:0048302)
0.0	0.1	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.1	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:0085020	protein K27-linked ubiquitination(GO:0044314) protein K6-linked ubiquitination(GO:0085020)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.2	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.0	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0018342	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.0	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.1	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.1	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.2	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.0	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.0	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.4	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.0	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.0	GO:0010939	regulation of necrotic cell death(GO:0010939)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.8	GO:0033238	regulation of cellular amine metabolic process(GO:0033238)
0.0	0.1	GO:0046629	gamma-delta T cell activation(GO:0046629)
0.0	0.1	GO:0046688	response to copper ion(GO:0046688)
0.0	0.0	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.3	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0	0.1	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.2	GO:0055070	copper ion homeostasis(GO:0055070)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0032091	negative regulation of protein binding(GO:0032091)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.0	GO:0002251	organ or tissue specific immune response(GO:0002251)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.4	GO:0006490	dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.5	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.1	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.1	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.2	GO:0042102	positive regulation of T cell proliferation(GO:0042102)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.5	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0045909	positive regulation of vasodilation(GO:0045909)
0.0	0.1	GO:0032401	establishment of melanosome localization(GO:0032401)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.2	GO:0007032	endosome organization(GO:0007032)
0.0	0.0	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.2	GO:0000956	nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0	0.2	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.0	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:1903299	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.1	GO:0034375	high-density lipoprotein particle remodeling(GO:0034375)
0.0	0.0	GO:0001865	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.2	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	1.2	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.3	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0050702	interleukin-1 beta secretion(GO:0050702)
0.0	0.3	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
0.0	0.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.3	GO:0036503	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.1	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.0	GO:0032418	lysosome localization(GO:0032418)
0.0	0.0	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0016577	histone demethylation(GO:0016577)
0.0	0.0	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.0	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.0	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.0	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.0	0.0	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.0	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.0	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.0	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0016098	monoterpenoid metabolic process(GO:0016098)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	1.1	GO:0001772	immunological synapse(GO:0001772)
0.1	0.2	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.2	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.2	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.3	GO:0000125	PCAF complex(GO:0000125)
0.0	0.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.6	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.3	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.2	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.2	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0038201	TORC1 complex(GO:0031931) TOR complex(GO:0038201)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.4	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.2	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.0	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.4	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.5	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.2	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.9	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0045273	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.2	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.4	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.0	GO:0043230	extracellular organelle(GO:0043230)
0.0	0.6	GO:0055037	recycling endosome(GO:0055037)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0022624	proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.9	GO:0005643	nuclear pore(GO:0005643)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.6	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.5	GO:0000922	spindle pole(GO:0000922)
0.0	0.8	GO:0000786	nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0	0.1	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.2	GO:0032155	cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0	0.5	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.5	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.3	GO:0005814	centriole(GO:0005814)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.0	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.0	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.4	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.4	GO:0005521	lamin binding(GO:0005521)
0.1	0.4	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.4	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.2	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1	0.6	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.2	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.3	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1	0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.1	0.2	GO:0045569	TRAIL binding(GO:0045569)
0.1	0.3	GO:0031013	troponin I binding(GO:0031013)
0.1	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.6	GO:0005035	death receptor activity(GO:0005035)
0.0	0.2	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	2.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.4	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.2	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.0	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.2	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.1	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.2	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.2	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0046977	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.3	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.4	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	1.9	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0009374	biotin binding(GO:0009374)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.6	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.3	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.3	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.2	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.3	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.2	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.0	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.0	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.5	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.0	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.0	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.3	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0046527	glucosyltransferase activity(GO:0046527)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.2	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.0	GO:0032138	single base insertion or deletion binding(GO:0032138)
0.0	0.1	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.3	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.1	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.0	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.4	GO:0003954	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.0	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0017069	snRNA binding(GO:0017069)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.6	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.0	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.3	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.0	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.0	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.2	GO:0002039	p53 binding(GO:0002039)
0.0	0.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0019201	nucleotide kinase activity(GO:0019201)
0.0	0.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.0	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.3	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.2	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.7	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.3	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.3	GO:0042393	histone binding(GO:0042393)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.0	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.9	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.2	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.7	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.8	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.9	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	1.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.7	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.5	PID MYC PATHWAY	C-MYC pathway
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.9	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.5	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.3	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.2	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.3	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.3	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.5	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	1.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.1	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.5	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.5	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.0	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.5	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	1.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.1	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.6	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.8	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.0	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.3	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.7	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.1	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.2	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.0	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.2	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.4	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.3	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.0	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.0	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.6	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.2	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0	0.2	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways

Results for REL

Z-value: 1.07

Motif logo

Transcription factors associated with REL

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the REL motif across conditions

Conditions sorted by the z-value of the REL motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: