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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for REL

Z-value: 1.07

Motif logo

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Transcription factors associated with REL

Gene Symbol Gene ID Gene Info
ENSG00000162924.9 REL

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
RELchr2_61108808_611095333790.8679690.694.1e-02Click!
RELchr2_61109789_6111046913380.4490240.571.1e-01Click!
RELchr2_61094888_61095039136930.184224-0.511.6e-01Click!
RELchr2_61093725_61093876148560.181757-0.511.6e-01Click!
RELchr2_61111507_6111169128080.2681500.491.9e-01Click!

Activity of the REL motif across conditions

Conditions sorted by the z-value of the REL motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr20_4795121_4795462 0.70 RASSF2
Ras association (RalGDS/AF-6) domain family member 2
478
0.82
chr13_31309966_31310295 0.62 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
485
0.88
chr12_76425402_76425553 0.61 PHLDA1
pleckstrin homology-like domain, family A, member 1
93
0.95
chr9_117145261_117145418 0.56 AKNA
AT-hook transcription factor
4904
0.23
chr11_69065156_69065401 0.53 MYEOV
myeloma overexpressed
3653
0.34
chr4_100738641_100738957 0.52 DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
796
0.72
chr9_123688442_123688941 0.52 TRAF1
TNF receptor-associated factor 1
2356
0.33
chr12_55375572_55375878 0.52 TESPA1
thymocyte expressed, positive selection associated 1
103
0.98
chr12_122228420_122228575 0.52 RHOF
ras homolog family member F (in filopodia)
2769
0.23
chr17_41738065_41738244 0.50 MEOX1
mesenchyme homeobox 1
777
0.64
chr21_32554686_32554857 0.50 TIAM1
T-cell lymphoma invasion and metastasis 1
52232
0.17
chr8_59717634_59717850 0.49 ENSG00000201231
.
9369
0.29
chr7_30766706_30766866 0.48 INMT
indolethylamine N-methyltransferase
24965
0.16
chr12_2977204_2977355 0.48 FOXM1
forkhead box M1
468
0.67
chr6_138028959_138029110 0.48 ENSG00000216097
.
9051
0.27
chr19_49362125_49362344 0.47 PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
397
0.71
chr17_46506744_46506936 0.46 SKAP1
src kinase associated phosphoprotein 1
712
0.61
chr22_37881738_37882044 0.46 MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
534
0.71
chr1_9688741_9688898 0.45 PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
22971
0.15
chr14_22994691_22994955 0.44 TRAJ15
T cell receptor alpha joining 15
3757
0.14
chr20_48419063_48419214 0.43 ENSG00000252540
.
7790
0.16
chr1_160766445_160766727 0.43 LY9
lymphocyte antigen 9
609
0.72
chr3_50644253_50644482 0.43 CISH
cytokine inducible SH2-containing protein
4836
0.16
chr6_9521344_9521640 0.42 OFCC1
orofacial cleft 1 candidate 1
412008
0.01
chr1_31227757_31227908 0.42 LAPTM5
lysosomal protein transmembrane 5
2835
0.23
chr19_39106930_39107372 0.42 MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
1413
0.27
chr16_28996496_28996848 0.41 LAT
linker for activation of T cells
11
0.94
chr22_17568454_17568717 0.41 IL17RA
interleukin 17 receptor A
2736
0.23
chr1_26316985_26317339 0.41 PAFAH2
platelet-activating factor acetylhydrolase 2, 40kDa
6950
0.1
chrX_76776329_76776480 0.40 FGF16
fibroblast growth factor 16
66756
0.13
chrX_53741093_53741244 0.39 HUWE1
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
27495
0.23
chr14_84023285_84023436 0.39 ENSG00000238561
.
193368
0.03
chrX_123480814_123480965 0.39 SH2D1A
SH2 domain containing 1A
450
0.9
chr15_81586254_81586487 0.38 IL16
interleukin 16
2884
0.28
chr9_134143747_134144006 0.38 FAM78A
family with sequence similarity 78, member A
2004
0.31
chr21_44036816_44036993 0.38 AP001626.2

34450
0.13
chr3_195913428_195913625 0.38 ENSG00000222335
.
15694
0.13
chr6_11852612_11852763 0.37 ADTRP
androgen-dependent TFPI-regulating protein
45408
0.18
chr21_42739358_42739509 0.37 MX2
myxovirus (influenza virus) resistance 2 (mouse)
2579
0.29
chr1_167599991_167600483 0.37 RP3-455J7.4

326
0.69
chr1_24830480_24830703 0.37 RCAN3
RCAN family member 3
1204
0.45
chr1_150737104_150737638 0.37 CTSS
cathepsin S
897
0.5
chr9_134154077_134154228 0.37 FAM78A
family with sequence similarity 78, member A
2218
0.29
chr12_9913587_9913738 0.37 CD69
CD69 molecule
165
0.94
chr13_34184837_34185306 0.37 RFC3
replication factor C (activator 1) 3, 38kDa
207115
0.02
chr1_8000859_8001010 0.37 TNFRSF9
tumor necrosis factor receptor superfamily, member 9
8
0.98
chr12_104856651_104856876 0.37 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
5984
0.3
chr9_134604865_134605016 0.37 ENSG00000240853
.
4086
0.24
chr16_80690406_80690960 0.36 ENSG00000265341
.
8777
0.18
chr13_74807358_74807666 0.36 ENSG00000206617
.
55839
0.16
chr5_40490586_40490737 0.36 ENSG00000199552
.
164404
0.03
chr22_50631230_50631436 0.36 TRABD
TraB domain containing
110
0.82
chr17_61920040_61920386 0.35 SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
87
0.94
chr7_44790648_44790799 0.35 ZMIZ2
zinc finger, MIZ-type containing 2
2193
0.28
chr17_8643854_8644020 0.35 CCDC42
coiled-coil domain containing 42
4168
0.22
chr17_72735282_72735631 0.35 RAB37
RAB37, member RAS oncogene family
2085
0.18
chr17_40440128_40440459 0.35 STAT5A
signal transducer and activator of transcription 5A
194
0.91
chr3_71833354_71833608 0.34 PROK2
prokineticin 2
731
0.68
chr11_64636867_64637025 0.34 EHD1
EH-domain containing 1
6192
0.1
chr3_33800152_33800303 0.34 PDCD6IP
programmed cell death 6 interacting protein
39617
0.18
chr17_56421831_56421982 0.34 SUPT4H1
suppressor of Ty 4 homolog 1 (S. cerevisiae)
7116
0.11
chr9_139927070_139927409 0.34 FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
223
0.78
chr6_119029777_119030724 0.34 CEP85L
centrosomal protein 85kDa-like
981
0.69
chr6_10532255_10532677 0.33 GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
3877
0.23
chr16_1013980_1014176 0.33 LMF1
lipase maturation factor 1
44
0.96
chr1_93443435_93443586 0.33 ENSG00000239710
.
2830
0.16
chr20_55967108_55967259 0.33 RBM38
RNA binding motif protein 38
103
0.93
chr1_66799510_66799957 0.33 PDE4B
phosphodiesterase 4B, cAMP-specific
1861
0.5
chr19_59077926_59078077 0.33 MZF1
myeloid zinc finger 1
6141
0.08
chr1_154926399_154926550 0.33 PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
2106
0.14
chr1_166459489_166459697 0.33 FAM78B
family with sequence similarity 78, member B
323387
0.01
chr4_56814187_56814608 0.33 CEP135
centrosomal protein 135kDa
640
0.74
chr22_37563414_37563565 0.32 RP1-151B14.6

692
0.56
chr21_42741228_42741619 0.32 MX2
myxovirus (influenza virus) resistance 2 (mouse)
589
0.77
chr8_126964027_126964178 0.32 ENSG00000206695
.
50907
0.19
chr4_10734070_10734358 0.32 CLNK
cytokine-dependent hematopoietic cell linker
47725
0.2
chr2_87782164_87782461 0.32 RP11-1399P15.1

4759
0.34
chr3_49314185_49314445 0.32 C3orf62
chromosome 3 open reading frame 62
337
0.78
chr9_132650035_132650502 0.32 FNBP1
formin binding protein 1
31321
0.13
chr19_16439255_16439417 0.32 KLF2
Kruppel-like factor 2
3685
0.18
chr22_44392181_44392448 0.32 PARVB
parvin, beta
2777
0.29
chr21_35305474_35305968 0.31 LINC00649
long intergenic non-protein coding RNA 649
2203
0.25
chr17_3865236_3865510 0.31 ATP2A3
ATPase, Ca++ transporting, ubiquitous
2212
0.29
chr15_31638589_31638828 0.31 KLF13
Kruppel-like factor 13
6572
0.32
chr1_19254411_19254592 0.31 IFFO2
intermediate filament family orphan 2
16015
0.16
chr2_214108249_214108400 0.31 SPAG16
sperm associated antigen 16
40789
0.21
chr10_15367555_15367706 0.31 FAM171A1
family with sequence similarity 171, member A1
45428
0.17
chr2_113932280_113932569 0.31 AC016683.5

490
0.59
chr22_30475055_30475206 0.31 HORMAD2
HORMA domain containing 2
1033
0.38
chr17_14207181_14207332 0.31 HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
2856
0.35
chr20_3888044_3888195 0.31 ENSG00000199024
.
10022
0.14
chr20_827167_827339 0.31 FAM110A
family with sequence similarity 110, member A
1486
0.47
chr11_46141542_46141818 0.31 PHF21A
PHD finger protein 21A
267
0.92
chrX_57936749_57936967 0.31 ZXDA
zinc finger, X-linked, duplicated A
209
0.97
chr5_39199802_39200193 0.30 FYB
FYN binding protein
3132
0.36
chr16_14109259_14109410 0.30 MKL2
MKL/myocardin-like 2
55844
0.14
chr3_150917377_150917528 0.30 GPR171
G protein-coupled receptor 171
3527
0.19
chr3_134515712_134515902 0.30 EPHB1
EPH receptor B1
824
0.64
chr9_35649649_35650491 0.30 SIT1
signaling threshold regulating transmembrane adaptor 1
867
0.32
chr5_1105065_1105874 0.30 SLC12A7
solute carrier family 12 (potassium/chloride transporter), member 7
6681
0.19
chrX_123373984_123374135 0.30 ENSG00000252693
.
42466
0.19
chr6_119450513_119450664 0.30 FAM184A
family with sequence similarity 184, member A
19764
0.22
chr20_11435441_11435592 0.30 ENSG00000222281
.
364223
0.01
chr18_46477576_46477867 0.30 SMAD7
SMAD family member 7
640
0.78
chr6_135501734_135502104 0.30 MYB
v-myb avian myeloblastosis viral oncogene homolog
534
0.78
chr8_23075544_23076103 0.30 ENSG00000246582
.
6161
0.12
chr19_46148940_46149188 0.30 EML2
echinoderm microtubule associated protein like 2
177
0.87
chr2_238604951_238605166 0.29 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
4076
0.27
chr16_14380187_14380356 0.29 ENSG00000201075
.
10909
0.18
chr8_79716569_79716762 0.29 IL7
interleukin 7
498
0.88
chr14_93427433_93427584 0.29 CHGA
chromogranin A (parathyroid secretory protein 1)
37987
0.18
chr1_156023968_156024197 0.29 LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
461
0.42
chr2_202129112_202129390 0.29 CASP8
caspase 8, apoptosis-related cysteine peptidase
2572
0.28
chr8_37751638_37751789 0.29 RAB11FIP1
RAB11 family interacting protein 1 (class I)
5259
0.15
chr17_46969511_46969711 0.29 ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
516
0.65
chr19_4338579_4338993 0.29 STAP2
signal transducing adaptor family member 2
20
0.91
chr17_70418844_70419055 0.29 ENSG00000200783
.
241342
0.02
chr1_147229260_147229411 0.29 RP11-433J22.2

91
0.97
chr2_96455429_96455580 0.29 AC008268.2

2464
0.4
chr6_135484621_135484772 0.29 MYB
v-myb avian myeloblastosis viral oncogene homolog
17757
0.18
chr15_45409056_45409207 0.28 DUOX2
dual oxidase 2
2589
0.14
chr16_26606103_26606254 0.28 ENSG00000264935
.
141372
0.05
chr21_45564255_45564539 0.28 C21orf33
chromosome 21 open reading frame 33
8396
0.15
chrX_40429955_40430133 0.28 ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
10102
0.21
chr10_47640402_47640757 0.28 ANTXRLP1
anthrax toxin receptor-like pseudogene 1
4212
0.25
chr1_155220339_155220564 0.28 FAM189B
family with sequence similarity 189, member B
4248
0.07
chr2_10548224_10548465 0.28 HPCAL1
hippocalcin-like 1
11803
0.19
chr17_7819751_7819902 0.28 AC025335.1

555
0.56
chr16_83377985_83378136 0.28 RP11-543N12.1

53532
0.15
chr16_11678014_11678655 0.28 LITAF
lipopolysaccharide-induced TNF factor
1895
0.35
chr13_28363625_28363776 0.28 GSX1
GS homeobox 1
3080
0.29
chr9_100854419_100854570 0.28 TRIM14
tripartite motif containing 14
349
0.87
chr9_117969296_117969447 0.27 DEC1
deleted in esophageal cancer 1
65274
0.14
chr17_66286056_66286766 0.27 SLC16A6
solute carrier family 16, member 6
846
0.47
chr20_35272612_35272763 0.27 SLA2
Src-like-adaptor 2
1597
0.3
chr21_32930574_32931128 0.27 TIAM1
T-cell lymphoma invasion and metastasis 1
439
0.64
chr10_73119134_73119285 0.27 ENSG00000238918
.
34124
0.15
chrX_128915626_128915992 0.27 SASH3
SAM and SH3 domain containing 3
1849
0.35
chrX_9979270_9979421 0.27 WWC3
WWC family member 3
4257
0.22
chr18_13465441_13465744 0.27 LDLRAD4
low density lipoprotein receptor class A domain containing 4
578
0.59
chr10_15211128_15211858 0.27 NMT2
N-myristoyltransferase 2
801
0.67
chr12_56881156_56881307 0.27 GLS2
glutaminase 2 (liver, mitochondrial)
671
0.58
chr17_76642017_76642260 0.27 ENSG00000252391
.
50741
0.12
chr17_74523964_74524115 0.27 CYGB
cytoglobin
4108
0.1
chr11_2322055_2322323 0.27 C11orf21
chromosome 11 open reading frame 21
954
0.34
chr5_96232081_96232313 0.27 ERAP2
endoplasmic reticulum aminopeptidase 2
7276
0.18
chr6_138191751_138192709 0.26 RP11-356I2.4

2860
0.28
chr3_195839047_195839198 0.26 TFRC
transferrin receptor
30062
0.14
chr19_4015164_4015315 0.26 PIAS4
protein inhibitor of activated STAT, 4
7595
0.11
chr3_32502059_32502315 0.26 CMTM6
CKLF-like MARVEL transmembrane domain containing 6
42713
0.15
chr1_151735692_151735974 0.26 OAZ3
ornithine decarboxylase antizyme 3
123
0.48
chrX_102565057_102565303 0.26 BEX2
brain expressed X-linked 2
683
0.63
chr4_38320716_38321108 0.26 ENSG00000221495
.
80678
0.11
chr8_1953776_1953973 0.26 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
31830
0.2
chr9_139424881_139425156 0.26 ENSG00000263403
.
10940
0.09
chr13_50698385_50698672 0.26 DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
42221
0.15
chr8_8202203_8202575 0.26 SGK223
Tyrosine-protein kinase SgK223
36868
0.18
chr2_201987300_201987657 0.26 CFLAR
CASP8 and FADD-like apoptosis regulator
278
0.87
chr11_104971227_104972126 0.26 CASP1
caspase 1, apoptosis-related cysteine peptidase
482
0.32
chr18_43268798_43268949 0.26 SLC14A2
solute carrier family 14 (urea transporter), member 2
22766
0.16
chr18_42306038_42306201 0.26 SETBP1
SET binding protein 1
28990
0.26
chr11_65341832_65341983 0.26 EHBP1L1
EH domain binding protein 1-like 1
1602
0.16
chr11_441985_442183 0.26 ANO9
anoctamin 9
73
0.92
chr1_6520532_6520815 0.26 TNFRSF25
tumor necrosis factor receptor superfamily, member 25
5017
0.12
chr1_151030425_151030576 0.26 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
266
0.79
chr1_117297247_117297398 0.26 CD2
CD2 molecule
233
0.94
chr9_100820741_100820957 0.26 NANS
N-acetylneuraminic acid synthase
1828
0.32
chr9_140213393_140213574 0.26 NRARP
NOTCH-regulated ankyrin repeat protein
16780
0.09
chr2_179896702_179896868 0.26 ENSG00000252000
.
8680
0.23
chr15_45493492_45493643 0.26 SHF
Src homology 2 domain containing F
194
0.81
chr12_24893684_24893835 0.26 ENSG00000240481
.
34037
0.21
chr10_12085427_12085707 0.26 UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
544
0.77
chr7_5863313_5863517 0.26 ZNF815P
zinc finger protein 815, pseudogene
577
0.73
chr16_32199480_32199834 0.25 HERC2P4
hect domain and RLD 2 pseudogene 4
223
0.95
chr7_74057672_74058172 0.25 GTF2I
general transcription factor IIi
14089
0.22
chrX_48793999_48794379 0.25 PIM2
pim-2 oncogene
17888
0.08
chr1_226922169_226922483 0.25 ITPKB
inositol-trisphosphate 3-kinase B
2833
0.32
chr9_37529043_37529220 0.25 RP11-613M10.6

19984
0.15
chr16_68798920_68799109 0.25 ENSG00000200558
.
22631
0.14
chr19_45271245_45271464 0.25 ENSG00000253027
.
3147
0.15
chr19_39825870_39826313 0.25 GMFG
glia maturation factor, gamma
554
0.58
chr1_40781658_40781894 0.25 COL9A2
collagen, type IX, alpha 2
586
0.72
chr9_38227227_38227501 0.25 ENSG00000238313
.
36960
0.19
chr19_41869552_41869735 0.25 TMEM91
transmembrane protein 91
318
0.54
chr12_109022749_109023024 0.25 RP11-689B22.2

423
0.76
chr9_116139439_116139752 0.25 HDHD3
haloacid dehalogenase-like hydrolase domain containing 3
316
0.84
chr2_202101089_202101263 0.25 CASP8
caspase 8, apoptosis-related cysteine peptidase
2947
0.25
chr11_34255826_34255987 0.25 ENSG00000201867
.
45185
0.17
chr11_69457554_69457705 0.25 CCND1
cyclin D1
1655
0.41
chr17_47819247_47819793 0.25 FAM117A
family with sequence similarity 117, member A
17631
0.14
chr1_113162566_113162826 0.24 ST7L
suppression of tumorigenicity 7 like
656
0.47
chr3_112215334_112215665 0.24 BTLA
B and T lymphocyte associated
2706
0.33
chr17_75103749_75103900 0.24 ENSG00000234912
.
18435
0.18
chr7_134855680_134855894 0.24 C7orf49
chromosome 7 open reading frame 49
240
0.89
chr7_5183512_5184010 0.24 ZNF890P
zinc finger protein 890, pseudogene
16335
0.17
chr17_4850386_4850673 0.24 PFN1
profilin 1
235
0.73
chr13_71865361_71865710 0.24 DACH1
dachshund homolog 1 (Drosophila)
575372
0.0
chr2_106363775_106364396 0.24 NCK2
NCK adaptor protein 2
1897
0.48
chrX_100183468_100183619 0.24 XKRX
XK, Kell blood group complex subunit-related, X-linked
355
0.88
chr16_28152825_28152997 0.24 XPO6
exportin 6
28311
0.15

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of REL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.4 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.4 GO:0072338 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1 0.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.3 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.4 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 0.3 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.2 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 0.2 GO:0097205 regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.1 0.3 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.1 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.1 0.3 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 0.2 GO:0016048 detection of temperature stimulus(GO:0016048)
0.1 0.1 GO:0070254 mucus secretion(GO:0070254)
0.1 0.3 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.2 GO:0032682 negative regulation of chemokine production(GO:0032682)
0.1 0.1 GO:0002830 positive regulation of type 2 immune response(GO:0002830) positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1 0.3 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.1 0.3 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.1 GO:0071025 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.1 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1 0.5 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.1 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.1 0.2 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.1 0.2 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1 0.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.2 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.1 0.2 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.1 0.2 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 0.2 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.1 0.2 GO:0070141 response to UV-A(GO:0070141)
0.0 0.2 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.0 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.2 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.3 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.2 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0052169 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0060087 relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.4 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.5 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.1 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0 0.2 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0060872 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0 0.0 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0051323 metaphase(GO:0051323)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.0 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.1 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475)
0.0 0.1 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.1 GO:0021554 optic nerve development(GO:0021554)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.3 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.6 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.0 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.2 GO:1903078 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.0 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0032649 regulation of interferon-gamma production(GO:0032649)
0.0 0.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0016241 regulation of macroautophagy(GO:0016241) negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.0 GO:0070076 histone lysine demethylation(GO:0070076)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0032735 positive regulation of interleukin-12 production(GO:0032735)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.5 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.4 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0070828 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0048548 regulation of pinocytosis(GO:0048548)
0.0 0.2 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.2 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.0 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.0 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.0 GO:0035751 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0035067 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0002467 germinal center formation(GO:0002467)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.3 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.0 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.0 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.8 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0048302 regulation of isotype switching to IgG isotypes(GO:0048302)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.1 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0 0.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0085020 protein K27-linked ubiquitination(GO:0044314) protein K6-linked ubiquitination(GO:0085020)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.0 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.0 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.0 0.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.0 GO:0010939 regulation of necrotic cell death(GO:0010939)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.8 GO:0033238 regulation of cellular amine metabolic process(GO:0033238)
0.0 0.1 GO:0046629 gamma-delta T cell activation(GO:0046629)
0.0 0.1 GO:0046688 response to copper ion(GO:0046688)
0.0 0.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.1 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0002251 organ or tissue specific immune response(GO:0002251)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.4 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.1 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.5 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0045909 positive regulation of vasodilation(GO:0045909)
0.0 0.1 GO:0032401 establishment of melanosome localization(GO:0032401)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.0 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.2 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.0 GO:1903299 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.0 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 1.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.3 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0050702 interleukin-1 beta secretion(GO:0050702)
0.0 0.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.3 GO:0036503 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0 0.1 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.0 GO:0032418 lysosome localization(GO:0032418)
0.0 0.0 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.0 GO:0016577 histone demethylation(GO:0016577)
0.0 0.0 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.0 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.0 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.0 GO:0097384 cellular lipid biosynthetic process(GO:0097384)
0.0 0.0 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.0 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0001832 blastocyst growth(GO:0001832)
0.0 0.0 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.0 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.0 GO:0042772 DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 1.1 GO:0001772 immunological synapse(GO:0001772)
0.1 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0038201 TORC1 complex(GO:0031931) TOR complex(GO:0038201)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.0 GO:0043230 extracellular organelle(GO:0043230)
0.0 0.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0022624 proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.0 GO:0032059 bleb(GO:0032059)
0.0 0.6 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.8 GO:0000786 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0 0.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.0 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0032155 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.3 GO:0005814 centriole(GO:0005814)
0.0 0.0 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.2 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.3 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.3 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.6 GO:0005035 death receptor activity(GO:0005035)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 2.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0070061 fructose binding(GO:0070061)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0046977 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 1.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0009374 biotin binding(GO:0009374)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.3 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.0 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.0 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.0 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.4 GO:0003954 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0017069 snRNA binding(GO:0017069)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.6 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.0 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.0 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.0 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0019201 nucleotide kinase activity(GO:0019201)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.3 GO:0042393 histone binding(GO:0042393)
0.0 0.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.0 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.7 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 1.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.0 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.6 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.0 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.0 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.2 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways